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WHAT THIS STUDY ADDS: The use of high-dose IVIG for severe isoimmune hemolytic jaundice in late-preterm and term infants is associated with a higher incidence of necrotizing enterocolitis.","publication_date":"2010,,","publication_name":"PEDIATRICS","grobid_abstract_attachment_id":"72718243"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Intravenous Immunoglobulin and Necrotizing Enterocolitis in Newborns With Hemolytic Disease","broadcastable":false,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [42202147]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "control"; window.loswp.useOptimizedScribd4genScript = false; window.loginModal = {}; window.loginModal.appleClientId = 'edu.academia.applesignon'; window.userInChina = "false";</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div class="ds-loswp-container"><div class="ds-work-card--grid-container"><div class="ds-work-card--container js-loswp-work-card ds-work-card--no-bottom-spacing"><div class="ds-work-card--cover"><div class="ds-work-cover--wrapper"><div class="ds-work-cover--container"><button class="ds-work-cover--clickable js-swp-download-button" data-signup-modal="{"location":"swp-splash-paper-cover","attachmentId":72718243,"attachmentType":"pdf"}"><img alt="First page of “Intravenous Immunoglobulin and Necrotizing Enterocolitis in Newborns With Hemolytic Disease”" class="ds-work-cover--cover-thumbnail" src="https://0.academia-photos.com/attachment_thumbnails/72718243/mini_magick20211015-21056-guoage.png?1634333258" /><img alt="PDF Icon" class="ds-work-cover--file-icon" src="//a.academia-assets.com/images/single_work_splash/adobe_icon.svg" /><div class="ds-work-cover--hover-container"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span><p>Download Free PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">Intravenous Immunoglobulin and Necrotizing Enterocolitis in Newborns With Hemolytic Disease</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="42202147" href="https://independent.academia.edu/FBotetmussons"><img alt="Profile image of F. Botet-mussons" class="ds-work-card--author-avatar" src="//a.academia-assets.com/images/s65_no_pic.png" />F. Botet-mussons</a></div><div class="ds-work-card--detail"><p class="ds-work-card--detail ds2-5-body-sm">2010, PEDIATRICS</p><div class="ds-work-card--work-metadata"><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">visibility</span><p class="ds2-5-body-sm" id="work-metadata-view-count">…</p></div><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">description</span><p class="ds2-5-body-sm">8 pages</p></div><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">link</span><p class="ds2-5-body-sm">1 file</p></div></div><script>(async () => { const workId = 58184450; const worksViewsPath = "/v0/works/views?subdomain_param=api&work_ids%5B%5D=58184450"; const getWorkViews = async (workId) => { const response = await fetch(worksViewsPath); if (!response.ok) { throw new Error('Failed to load work views'); } const data = await response.json(); return data.views[workId]; }; // Get the view count for the work - we send this immediately rather than waiting for // the DOM to load, so it can be available as soon as possible (but without holding up // the backend or other resource requests, because it's a bit expensive and not critical). const viewCount = await getWorkViews(workId); const updateViewCount = (viewCount) => { try { const viewCountNumber = parseInt(viewCount, 10); if (viewCountNumber === 0) { // Remove the whole views element if there are zero views. document.getElementById('work-metadata-view-count')?.parentNode?.remove(); return; } const commaizedViewCount = viewCountNumber.toLocaleString(); const viewCountBody = document.getElementById('work-metadata-view-count'); if (!viewCountBody) { throw new Error('Failed to find work views element'); } viewCountBody.textContent = `${commaizedViewCount} views`; } catch (error) { // Remove the whole views element if there was some issue parsing. document.getElementById('work-metadata-view-count')?.parentNode?.remove(); throw new Error(`Failed to parse view count: ${viewCount}`, error); } }; // If the DOM is still loading, wait for it to be ready before updating the view count. if (document.readyState === "loading") { document.addEventListener('DOMContentLoaded', () => { updateViewCount(viewCount); }); // Otherwise, just update it immediately. } else { updateViewCount(viewCount); } })();</script></div><p class="ds-work-card--work-abstract ds-work-card--detail ds2-5-body-md">WHAT'S KNOWN ON THIS SUBJECT: Treatment with phototherapy and high-dose IVIG for newborns with significant hyperbilirubinemia caused by isoimmune hemolytic jaundice (Rh or ABO incompatibility) reduces the need for exchange transfusion. 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data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Intravenous Immunoglobulin in Neonates: Current Perspective","attachmentId":76888372,"attachmentType":"pdf","work_url":"https://www.academia.edu/65177755/Intravenous_Immunoglobulin_in_Neonates_Current_Perspective","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/65177755/Intravenous_Immunoglobulin_in_Neonates_Current_Perspective"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="7" data-entity-id="107599668" data-sort-order="default"><a 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Bar-oz</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Vox Sanguinis, 1995</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Carboxyhemoglobin Levels in Neonatal Immune Hemolytic Jaundice Treated with Intravenous Gammaglobulin","attachmentId":66857629,"attachmentType":"pdf","work_url":"https://www.academia.edu/48037300/Carboxyhemoglobin_Levels_in_Neonatal_Immune_Hemolytic_Jaundice_Treated_with_Intravenous_Gammaglobulin","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" 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haemolytic jaundice</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="36135314" href="https://independent.academia.edu/EduardoNobileorazio">Eduardo Nobile-orazio</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Acta Paediatrica, 2007</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"High-dose intravenous immunoglobulin therapy in neonatal immune haemolytic jaundice","attachmentId":73050572,"attachmentType":"pdf","work_url":"https://www.academia.edu/58823552/High_dose_intravenous_immunoglobulin_therapy_in_neonatal_immune_haemolytic_jaundice","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a 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href="https://www.academia.edu/92091147/Rhesus_Isoimmunization_Late_onset_Hemolytic_Disease_of_the_Newborn_Without_Jaundice"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="13" data-entity-id="101632316" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/101632316/Necrotizing_enterocolitis_following_the_use_of_intravenous_immunoglobulin_for_haemolytic_disease_of_the_newborn">Necrotizing enterocolitis following the use of intravenous immunoglobulin for haemolytic disease of the newborn</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="269326364" 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href="https://www.academia.edu/101632316/Necrotizing_enterocolitis_following_the_use_of_intravenous_immunoglobulin_for_haemolytic_disease_of_the_newborn"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="14" data-entity-id="81479829" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/81479829/Use_of_intravenous_immunoglobulin_in_neonates_with_haemolytic_disease_and_immune_thrombocytopenia">Use of intravenous immunoglobulin in neonates with haemolytic disease and immune thrombocytopenia</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="102250065" 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href="https://www.academia.edu/81479829/Use_of_intravenous_immunoglobulin_in_neonates_with_haemolytic_disease_and_immune_thrombocytopenia"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="15" data-entity-id="74364074" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/74364074/Evaluation_of_Neonatal_Hemolytic_Jaundice_Clinical_and_Laboratory_Parameters">Evaluation of Neonatal Hemolytic Jaundice: Clinical and Laboratory Parameters</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="139554038" href="https://ffst.academia.edu/AnetCherepnalkovski">Anet Papazovska Cherepnalkovski</a></div><p 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class="ds-related-work--metadata ds2-5-body-xs">American journal of obstetrics and gynecology, 2018</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Postponing Early intrauterine Transfusion with Intravenous immunoglobulin Treatment; the PETIT study on severe hemolytic disease of the fetus and newborn","attachmentId":84265746,"attachmentType":"pdf","work_url":"https://www.academia.edu/76613226/Postponing_Early_intrauterine_Transfusion_with_Intravenous_immunoglobulin_Treatment_the_PETIT_study_on_severe_hemolytic_disease_of_the_fetus_and_newborn","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" 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Pediatrics, 1950</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Hemolytic disease of the newborn","attachmentId":70908007,"attachmentType":"pdf","work_url":"https://www.academia.edu/54639957/Hemolytic_disease_of_the_newborn","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/54639957/Hemolytic_disease_of_the_newborn"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="20" data-entity-id="121017681" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/121017681/Standard_Versus_Hyperimmune_Intravenous_Immunoglobulin_in_Preventing_or_Treating_Neonatal_Bacterial_Infections">Standard Versus Hyperimmune Intravenous Immunoglobulin in Preventing or Treating Neonatal Bacterial Infections</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="34877209" href="https://trick-computer.academia.edu/DavidCruess">David Cruess</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Clinics in Perinatology, 1993</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Standard Versus Hyperimmune Intravenous Immunoglobulin in Preventing or Treating Neonatal 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data-collection-position="25" data-entity-id="8603225" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/8603225/Follow_up_of_neonatal_jaundice_in_term_and_late_premature_newborns">Follow-up of neonatal jaundice in term and late premature newborns</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="17810010" href="https://independent.academia.edu/abimaelaranhanetto">abimael aranha netto</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Jornal De Pediatria, 2007</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Follow-up of neonatal jaundice in term and late premature 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