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Genetic testing supporting personalized cancer care

<!DOCTYPE html><html lang="en"><head><meta charSet="utf-8"/><meta name="viewport" content="width=device-width"/><title>Genetic testing supporting personalized cancer care</title><link href="https://www.invitae.com/us/providers/oncology/personalize-cancer-treatment" rel="canonical"/><meta content="Patients that have a hereditary genetic variant may benefit from personalized cancer treatments. Get a more complete story with genetic testing from Invitae." name="description"/><meta content="Patients that have a hereditary genetic variant may benefit from personalized cancer treatments. 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srcSet="//images.ctfassets.net/6at1y2gofdxy/5EAqVV5YNCdMHNt14WWQyR/1b58ac2d85ae482eca6fee6c205c0432/Logo_Labcorp_White.svg?fit=pad&amp;q=66&amp;w=300" type="image/svg+xml"/><source media="(min-width: 320px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/5EAqVV5YNCdMHNt14WWQyR/1b58ac2d85ae482eca6fee6c205c0432/Logo_Labcorp_White.svg?fit=pad&amp;q=66&amp;w=300" type="image/svg+xml"/><img alt="White labcorp logo" loading="lazy" src="//images.ctfassets.net/6at1y2gofdxy/5EAqVV5YNCdMHNt14WWQyR/1b58ac2d85ae482eca6fee6c205c0432/Logo_Labcorp_White.svg?fit=pad&amp;q=66&amp;w=300" data-testid="image"/></picture></div><p class="notification-banner--body"><span class="nv-markdown nv-markdown-inline"><strong>Exciting news:</strong> Invitae joins Labcorp to expand the future of genetic testing.</span><span class="notification-banner--link"> <a href="https://www.labcorp.com/labcorp-finalizes-acquisition-select-assets-invitae" rel="noreferrer noopener" target="_blank"><span class="">Learn more</span></a></span></p></div></div></dialog><main><section class="hero-shape-block--root hero-shape-block--cyprus-alt" id="2To7mobSoZWQHaNstvMBNn" data-cy="section-leadspaceWithShape-0"><div class="hero-shape-block--text-grid grid--grid nv-container"><div class="hero-shape-block--text"><h1 class="hero-shape-block--heading hero-shape-block--cyprus-alt nv-markdown nv-markdown-inline nv-headline">Help personalize your patients’ cancer treatment</h1><div class="hero-shape-block--actions"><a class="nv-button hero-shape-block--link" href="/us/providers/test-catalog/oncology" target="_self"><span class="">Explore tests</span></a><a class="nv-button nv-button-secondary hero-shape-block--link hero-shape-block--secondary-link" href="https://cloud.insights.invitae.com/oncology-rep-outreach" rel="noreferrer noopener" target="_blank"><span class="">Contact us</span></a></div></div></div><div class="hero-shape-block--img-grid grid--grid"><div class="hero-shape-block--picture hero-shape-block--img-overlay-wrapper-shape-outwards"><picture class="default-image--component-styles"><source media="(min-width: 1260px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/10z8Jt6UC5GwZgH4zFNvyI/a1be7fbdb30582925c1fba70b36479bb/doctor-and-patient.jpg?fit=pad&amp;q=66&amp;w=3780&amp;fm=webp" type="image/webp"/><source media="(min-width: 1260px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/10z8Jt6UC5GwZgH4zFNvyI/a1be7fbdb30582925c1fba70b36479bb/doctor-and-patient.jpg?fit=pad&amp;q=66&amp;w=3780" type="image/jpeg"/><source media="(min-width: 1020px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/10z8Jt6UC5GwZgH4zFNvyI/a1be7fbdb30582925c1fba70b36479bb/doctor-and-patient.jpg?fit=pad&amp;q=66&amp;w=3060&amp;fm=webp" type="image/webp"/><source media="(min-width: 1020px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/10z8Jt6UC5GwZgH4zFNvyI/a1be7fbdb30582925c1fba70b36479bb/doctor-and-patient.jpg?fit=pad&amp;q=66&amp;w=3060" type="image/jpeg"/><source media="(min-width: 720px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/10z8Jt6UC5GwZgH4zFNvyI/a1be7fbdb30582925c1fba70b36479bb/doctor-and-patient.jpg?fit=pad&amp;q=66&amp;w=2160&amp;fm=webp" type="image/webp"/><source media="(min-width: 720px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/10z8Jt6UC5GwZgH4zFNvyI/a1be7fbdb30582925c1fba70b36479bb/doctor-and-patient.jpg?fit=pad&amp;q=66&amp;w=2160" type="image/jpeg"/><source media="(min-width: 375px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/10z8Jt6UC5GwZgH4zFNvyI/a1be7fbdb30582925c1fba70b36479bb/doctor-and-patient.jpg?fit=pad&amp;q=66&amp;w=1125&amp;fm=webp" type="image/webp"/><source media="(min-width: 375px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/10z8Jt6UC5GwZgH4zFNvyI/a1be7fbdb30582925c1fba70b36479bb/doctor-and-patient.jpg?fit=pad&amp;q=66&amp;w=1125" type="image/jpeg"/><source media="(min-width: 360px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/10z8Jt6UC5GwZgH4zFNvyI/a1be7fbdb30582925c1fba70b36479bb/doctor-and-patient.jpg?fit=pad&amp;q=66&amp;w=1080&amp;fm=webp" type="image/webp"/><source media="(min-width: 360px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/10z8Jt6UC5GwZgH4zFNvyI/a1be7fbdb30582925c1fba70b36479bb/doctor-and-patient.jpg?fit=pad&amp;q=66&amp;w=1080" type="image/jpeg"/><source media="(min-width: 320px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/10z8Jt6UC5GwZgH4zFNvyI/a1be7fbdb30582925c1fba70b36479bb/doctor-and-patient.jpg?fit=pad&amp;q=66&amp;w=960&amp;fm=webp" type="image/webp"/><source media="(min-width: 320px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/10z8Jt6UC5GwZgH4zFNvyI/a1be7fbdb30582925c1fba70b36479bb/doctor-and-patient.jpg?fit=pad&amp;q=66&amp;w=960" type="image/jpeg"/><img alt="Woman receiving personalized treatment" class="animation-fade-in" loading="lazy" src="//images.ctfassets.net/6at1y2gofdxy/10z8Jt6UC5GwZgH4zFNvyI/a1be7fbdb30582925c1fba70b36479bb/doctor-and-patient.jpg?fit=pad&amp;q=66&amp;fm=webp&amp;w=3060" data-testid="image"/></picture></div></div></section><section class="stepper-hover-section--section stepper-hover-section--gray" id="wvgQMg4REQ2jkzT8nii73" data-cy="section-sectionStepperHover-1"><div class="stepper-hover-section--grid grid--grid nv-container"><header class="nv-container base-heading--center base-heading--base-heading stepper-hover-section--header"><h2 class="nv-mh2 stepper-hover-section--heading nv-markdown nv-markdown-inline">Across cancer types, universal hereditary cancer genetic testing can help personalize your care approach<sup>1</sup></h2></header><div class="stepper-hover-section--wrap-items"><div class="stepper-hover-section--items" role="list"><div class="stepper-hover-item--item stepper-hover-item--selected" id="4batkwoMVqTFmA1aWFNoLx" role="listitem"><button class="stepper-hover-item--header"><h3 class="nv-mh3 stepper-hover-item--heading nv-markdown nv-markdown-inline">Breast cancer</h3><div class="stepper-hover-item--caret"><svg height="13" viewBox="0 0 19 13" width="19" xmlns="http://www.w3.org/2000/svg"><title>Toggle</title><path d="M9.838 12.332l9.03-9.741c.176-.225.176-.609 0-.865L18.044.668c-.175-.224-.475-.224-.675 0L9.513 8.903 1.633.7C1.456.476 1.156.476.956.7L.13 1.758c-.175.224-.175.608 0 .865l9.031 9.709c.2.224.5.224.676 0z" fill-rule="evenodd"></path></svg></div></button><div class="stepper-hover-item--body-container"><div class="stepper-hover-item--body-content nv-markdown nv-body"><p>Genetic testing informs breast cancer patient care.</p><p><a href="https://www.invitae.com/us/providers/oncology/inform-breast-cancer-treatment">Learn more</a></p></div></div></div><div class="stepper-hover-item--item" id="X4zCxzclxPmwUQX2Xi7vl" role="listitem"><button class="stepper-hover-item--header"><h3 class="nv-mh3 stepper-hover-item--heading nv-markdown nv-markdown-inline">Colorectal cancer</h3><div class="stepper-hover-item--caret"><svg height="13" viewBox="0 0 19 13" width="19" xmlns="http://www.w3.org/2000/svg"><title>Toggle</title><path d="M9.838 12.332l9.03-9.741c.176-.225.176-.609 0-.865L18.044.668c-.175-.224-.475-.224-.675 0L9.513 8.903 1.633.7C1.456.476 1.156.476.956.7L.13 1.758c-.175.224-.175.608 0 .865l9.031 9.709c.2.224.5.224.676 0z" fill-rule="evenodd"></path></svg></div></button><div class="stepper-hover-item--body-container"><div class="stepper-hover-item--body-content nv-markdown nv-body"><p>Genetic testing can help optimize colorectal cancer patient care.</p><p><a href="https://www.invitae.com/us/providers/oncology/inform-colorectal-cancer-care">Learn more</a></p></div></div></div><div class="stepper-hover-item--item" id="ILDxoj4izhJePgy39DoeT" role="listitem"><button class="stepper-hover-item--header"><h3 class="nv-mh3 stepper-hover-item--heading nv-markdown nv-markdown-inline">Ovarian cancer</h3><div class="stepper-hover-item--caret"><svg height="13" viewBox="0 0 19 13" width="19" xmlns="http://www.w3.org/2000/svg"><title>Toggle</title><path d="M9.838 12.332l9.03-9.741c.176-.225.176-.609 0-.865L18.044.668c-.175-.224-.475-.224-.675 0L9.513 8.903 1.633.7C1.456.476 1.156.476.956.7L.13 1.758c-.175.224-.175.608 0 .865l9.031 9.709c.2.224.5.224.676 0z" fill-rule="evenodd"></path></svg></div></button><div class="stepper-hover-item--body-container"><div class="stepper-hover-item--body-content nv-markdown nv-body"><p>Over 20% of ovarian cancer patients have an inherited gene variant.<sup>1,2</sup> Hereditary genetic test results are important for identifying patients who need targeted therapy. Targeted treatments such as PARP inhibitors (sometimes preceded by platinum-based chemotherapy) can improve progression-free survival outcomes in both frontline and recurrent settings.<sup>3</sup></p><p>The <a href="https://www.invitae.com/en/providers/test-catalog/test-01101">Invitae Multi-Cancer Panel</a> is a cross-cancer test with 13 genes linked to ovarian cancer that can help guide treatment plans.</p></div></div></div><div class="stepper-hover-item--item" id="2jgPwv1kAwnQGwL6T5MvtS" role="listitem"><button class="stepper-hover-item--header"><h3 class="nv-mh3 stepper-hover-item--heading nv-markdown nv-markdown-inline">Pancreatic cancer</h3><div class="stepper-hover-item--caret"><svg height="13" viewBox="0 0 19 13" width="19" xmlns="http://www.w3.org/2000/svg"><title>Toggle</title><path d="M9.838 12.332l9.03-9.741c.176-.225.176-.609 0-.865L18.044.668c-.175-.224-.475-.224-.675 0L9.513 8.903 1.633.7C1.456.476 1.156.476.956.7L.13 1.758c-.175.224-.175.608 0 .865l9.031 9.709c.2.224.5.224.676 0z" fill-rule="evenodd"></path></svg></div></button><div class="stepper-hover-item--body-container"><div class="stepper-hover-item--body-content nv-markdown nv-body"><p>Up to 15% of pancreatic cancer patients have an inherited gene variant.<sup>1,4,5</sup> In a 2021 study, the majority (68%) of positive genetic results conferred eligibility for DNA damage repair (DDR) gene-specific precision therapies or clinical treatment trials.<sup>6</sup></p><p>The <a href="https://www.invitae.com/en/providers/test-catalog/test-01101">Invitae Multi-Cancer Panel</a> is a cross-cancer test with 20 genes linked to pancreatic cancer and may help guide treatment plans.</p></div></div></div><div class="stepper-hover-item--item" id="Dvs2OpbICkXm4YKKq3IVS" role="listitem"><button class="stepper-hover-item--header"><h3 class="nv-mh3 stepper-hover-item--heading nv-markdown nv-markdown-inline">Prostate cancer</h3><div class="stepper-hover-item--caret"><svg height="13" viewBox="0 0 19 13" width="19" xmlns="http://www.w3.org/2000/svg"><title>Toggle</title><path d="M9.838 12.332l9.03-9.741c.176-.225.176-.609 0-.865L18.044.668c-.175-.224-.475-.224-.675 0L9.513 8.903 1.633.7C1.456.476 1.156.476.956.7L.13 1.758c-.175.224-.175.608 0 .865l9.031 9.709c.2.224.5.224.676 0z" fill-rule="evenodd"></path></svg></div></button><div class="stepper-hover-item--body-container"><div class="stepper-hover-item--body-content nv-markdown nv-body"><p>Get actionable insights for prostate cancer.</p><p><a href="https://www.invitae.com/us/providers/urology/genetic-testing">Learn more</a></p></div></div></div></div></div></div></section><section class="banner-block--root banner-block--cyprus-light banner-block--full-width" id="67GFiMmYVieo2zzc8yBYpe" data-cy="section-bannerSection-2"><div class="nv-container"><div><h2 class="banner-block--heading nv-markdown nv-markdown-inline">Offer genetic testing without overwhelming your staff and patients</h2></div><div class="banner-block--body nv-markdown nv-body"><p>Invitae Reach<sup>TM</sup> partners with you and your genetic expert (if you have one) to streamline the genetic testing process with customizable solutions that easily integrate into your existing workflow. From the earliest point in your patient’s care to results and consultation, we’re with you in the here and now.</p><p>More information coming soon.</p></div><div></div></div></section><section class="text-and-media-section--root text-and-media-section--white text-and-media-section--text-and-media-section-root" id="5b81JHX3pk9HndhowCDA3Y" data-cy="section-textAndMediaSection-3"><div class="text-and-media-section--grid grid--grid nv-container"><div class="text-and-media-section--column text-and-media-section--media text-and-media-section--mobile-column-2 text-and-media-section--desktop-column-5 text-and-media-section--mobile-position-bottom text-and-media-section--desktop-position-left text-and-media-section--media-alignment-center text-and-media-section--video" data-testid="media"><div><div class=""><div aria-hidden="false" aria-label="Loading" class="nv-spinner nv-spinner-size--large" role="alert"><svg display="block" height="200" preserveAspectRatio="xMidYMid" 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style="animation-delay:0s;animation-play-state:running;-webkit-animation-delay:0s;-webkit-animation-play-state:running"><animate attributeName="r" begin="-1.9166666666666663s" dur="1.6666666666666665s" repeatCount="indefinite" values="2.4000000000000004;3.5999999999999996;2.4000000000000004"></animate><animate attributeName="cy" begin="-1.4999999999999998s" calcMode="spline" dur="1.6666666666666665s" keySplines="0.5 0 0.5 1;0.5 0 0.5 1" keyTimes="0;0.5;1" repeatCount="indefinite" values="36;64;36"></animate><animate attributeName="fill" begin="-1.9166666666666663s" dur="1.6666666666666665s" keyTimes="0;0.5;1" repeatCount="indefinite" values="#66bf7e;#9bca6e;#66bf7e"></animate></circle><circle cx="93.548" cy="36.608" fill="#80d1ca" r="2.855" style="animation-delay:0s;animation-play-state:running;-webkit-animation-delay:0s;-webkit-animation-play-state:running"><animate attributeName="r" begin="-2.7499999999999996s" dur="1.6666666666666665s" repeatCount="indefinite" values="2.4000000000000004;3.5999999999999996;2.4000000000000004"></animate><animate attributeName="cy" begin="-2.333333333333333s" calcMode="spline" dur="1.6666666666666665s" keySplines="0.5 0 0.5 1;0.5 0 0.5 1" keyTimes="0;0.5;1" repeatCount="indefinite" values="36;64;36"></animate><animate attributeName="fill" begin="-1.9166666666666663s" dur="1.6666666666666665s" keyTimes="0;0.5;1" repeatCount="indefinite" values="#80d1ca;#128279;#80d1ca"></animate></circle></svg></div></div></div></div><div class="text-and-media-section--column text-and-media-section--text text-and-media-section--mobile-column-2 text-and-media-section--desktop-column-5 text-and-media-section--mobile-position-bottom text-and-media-section--desktop-position-left text-and-media-section--media-alignment-center"><h2 class="nv-mh2 text-and-media-section--heading nv-markdown nv-markdown-inline">Shaping the world of genetic testing</h2><div class="text-and-media-section--body nv-markdown nv-body"><p>With groundbreaking research and over 2 million unique gene variants identified, we’re not waiting for the world to catch up; we’re shaping it with you. Universal hereditary cancer genetic testing can help transform care for your oncology patients.<sup>1,7-9</sup></p></div><div class="text-and-media-section--actions"></div></div></div></section><section class="columns-section--columns-section-container columns-section--white columns-section--columns-section-root" id="2oCpdfcps7cF5JjxPO6dwF" data-cy="section-columnsSection-4"><div class="grid--grid nv-container"><ul class="columns-section--columns-section-items-container" data-testid="columns-items"><li class="column-section-item--root columns-section--grid-item-1" data-testid="columns-item-6GTcFKVBmIjjbeBbCvkRJq" id="6GTcFKVBmIjjbeBbCvkRJq"><div class="column-section-item--image-body-container"><div class="column-section-item--text-container"><h3 class="nv-mh3 column-section-item--alignment column-section-item--header columns-section--text-left nv-markdown nv-markdown-inline">Without hereditary cancer genetic testing, a crucial part of their cancer puzzle may be missing</h3><div class="column-section-item--alignment column-section-item--body columns-section--text-left columns-section--items-list nv-markdown nv-body"><p>Patients who harbor hereditary variants could benefit from tailored management, including colorectal (<span style="font-family:&#x27;Times New Roman&#x27;;:">~</span>15%), breast (<span style="font-family:&#x27;Times New Roman&#x27;;:">~</span>12%), ovarian (<span style="font-family:&#x27;Times New Roman&#x27;;:">~</span>20%), prostate (<span style="font-family:&#x27;Times New Roman&#x27;;:">~</span>13%), and pancreatic (<span style="font-family:&#x27;Times New Roman&#x27;;:">~</span>15%) cancer.<sup>1</sup></p></div></div></div></li></ul></div></section><section class="banner-block--root banner-block--cyprus-light banner-block--no-body-root banner-block--full-width" id="OnwedHHMHcdguZ7HRy0Hp" data-cy="section-bannerSection-5"><div class="nv-container"><div><h2 class="banner-block--heading nv-markdown nv-markdown-inline">Data presented at the American Society of Clinical Oncology suggest hereditary cancer genetic testing is underutilized in cancer care<sup>10</sup></h2></div><div></div></div></section><section class="banner-fact-block--root banner-fact-block--white banner-fact-block--root" id="HacqQp2CB9UL4xvy6OznG" data-cy="section-sectionFactBanner-6"><div class="shape-component--root shape-component--shape-bottom-right shape-component--shape-curved-crop-corner" id="l51LOtNU4lasFKjJAL1Ei"><svg height="100%" id="curvedCropCornerShape" width="100%" xmlns="http://www.w3.org/2000/svg" class="shape-component--shape-teal"><path d="M0 238.468c119.333 35.688 232.03-6.086 338.092-125.323C386.597 58.615 452.566 20.9 536 0H0v238.468z" fill="#2C6BAA" fill-rule="evenodd"></path></svg></div><div class="banner-fact-block--grid grid--grid nv-container"><picture class="banner-fact-block--image default-image--component-styles"><source media="(min-width: 1260px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/4VHqHRrvGzj2KsbehQH28b/254461d9d46ca877b192056d24e56982/info-graphic.svg?fit=pad&amp;q=66&amp;w=500" type="image/svg+xml"/><source media="(min-width: 1020px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/4VHqHRrvGzj2KsbehQH28b/254461d9d46ca877b192056d24e56982/info-graphic.svg?fit=pad&amp;q=66&amp;w=500" type="image/svg+xml"/><source media="(min-width: 720px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/4VHqHRrvGzj2KsbehQH28b/254461d9d46ca877b192056d24e56982/info-graphic.svg?fit=pad&amp;q=66&amp;w=500" type="image/svg+xml"/><source media="(min-width: 375px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/4VHqHRrvGzj2KsbehQH28b/254461d9d46ca877b192056d24e56982/info-graphic.svg?fit=pad&amp;q=66&amp;w=500" type="image/svg+xml"/><source media="(min-width: 360px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/4VHqHRrvGzj2KsbehQH28b/254461d9d46ca877b192056d24e56982/info-graphic.svg?fit=pad&amp;q=66&amp;w=500" type="image/svg+xml"/><source media="(min-width: 320px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/4VHqHRrvGzj2KsbehQH28b/254461d9d46ca877b192056d24e56982/info-graphic.svg?fit=pad&amp;q=66&amp;w=500" type="image/svg+xml"/><img alt="1 in 8 – breast cancer patients have genetic variant" class="animation-fade-in" loading="lazy" src="//images.ctfassets.net/6at1y2gofdxy/4VHqHRrvGzj2KsbehQH28b/254461d9d46ca877b192056d24e56982/info-graphic.svg?fit=pad&amp;q=66&amp;w=500" data-testid="image"/></picture><div class="banner-fact-block--content banner-fact-block--content-left banner-fact-block--mobile-text-center"><h2 class="banner-fact-block--heading banner-fact-block--heading-large nv-markdown nv-markdown-inline">1 in 8 </h2><h3 class="banner-fact-block--subheading nv-markdown nv-markdown-inline">cancer patients may have an inherited gene variant</h3><div data-testid="fact-banner-body" class="banner-fact-block--body nv-markdown nv-body"><p>A <em>JAMA Oncology</em> study found that hereditary cancer genetic testing for all patients with cancer—including colorectal, breast, ovarian, prostate, and pancreatic—uncovered disease-causing (pathogenic) inherited variants in 13.3% of patients.<sup>1</sup></p></div></div></div></section><section class="text-and-media-section--root text-and-media-section--gray text-and-media-section--text-and-media-section-root" id="7GqjnHEKVPu8dwY4DZwXda" data-cy="section-textAndMediaSection-7"><div class="text-and-media-section--grid grid--grid nv-container"><div class="text-and-media-section--column text-and-media-section--media text-and-media-section--mobile-column-2 text-and-media-section--desktop-column-4 text-and-media-section--mobile-position-bottom text-and-media-section--desktop-position-left text-and-media-section--media-alignment-top" data-testid="media"><picture class="default-image--component-styles"><source media="(min-width: 1260px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/2EuGBXuwYFWVVcjAXWt4WR/0641d7a68f3fe96d4f4e2d73a99f83b1/42_Percent_Graphic.svg?fit=pad&amp;q=66&amp;w=500" type="image/svg+xml"/><source media="(min-width: 1020px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/2EuGBXuwYFWVVcjAXWt4WR/0641d7a68f3fe96d4f4e2d73a99f83b1/42_Percent_Graphic.svg?fit=pad&amp;q=66&amp;w=500" type="image/svg+xml"/><source media="(min-width: 720px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/2EuGBXuwYFWVVcjAXWt4WR/0641d7a68f3fe96d4f4e2d73a99f83b1/42_Percent_Graphic.svg?fit=pad&amp;q=66&amp;w=500" type="image/svg+xml"/><source media="(min-width: 375px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/2EuGBXuwYFWVVcjAXWt4WR/0641d7a68f3fe96d4f4e2d73a99f83b1/42_Percent_Graphic.svg?fit=pad&amp;q=66&amp;w=500" type="image/svg+xml"/><source media="(min-width: 360px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/2EuGBXuwYFWVVcjAXWt4WR/0641d7a68f3fe96d4f4e2d73a99f83b1/42_Percent_Graphic.svg?fit=pad&amp;q=66&amp;w=500" type="image/svg+xml"/><source media="(min-width: 320px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/2EuGBXuwYFWVVcjAXWt4WR/0641d7a68f3fe96d4f4e2d73a99f83b1/42_Percent_Graphic.svg?fit=pad&amp;q=66&amp;w=500" type="image/svg+xml"/><img alt="42%" class="animation-fade-in" loading="lazy" src="//images.ctfassets.net/6at1y2gofdxy/2EuGBXuwYFWVVcjAXWt4WR/0641d7a68f3fe96d4f4e2d73a99f83b1/42_Percent_Graphic.svg?fit=pad&amp;q=66&amp;w=500" data-testid="image"/></picture></div><div class="text-and-media-section--column text-and-media-section--text text-and-media-section--mobile-column-2 text-and-media-section--desktop-column-4 text-and-media-section--mobile-position-bottom text-and-media-section--desktop-position-left text-and-media-section--media-alignment-top"><h2 class="nv-mh2 text-and-media-section--heading nv-markdown nv-markdown-inline">Nearly half of those patients didn’t have a suggestive family history</h2><div class="text-and-media-section--body nv-markdown nv-body"><p>Testing only patients who meet guidelines criteria may lead to missing up to 42% of patients with an inherited disease-causing (pathogenic) variant.<sup>1</sup> Genetic testing for all cancer patients helps ensure you don’t miss genetic information that can guide their treatment.<sup>1</sup> Invitae’s simple workflow makes ordering tests easy.</p></div><div class="text-and-media-section--actions"></div></div></div></section><section class="banner-fact-block--root banner-fact-block--white banner-fact-block--image-bottom banner-fact-block--root" id="3do7i0KwBmFVIn7FIAT3be" data-cy="section-sectionFactBanner-8"><div class="banner-fact-block--grid grid--grid nv-container"><picture class="banner-fact-block--image banner-fact-block--image-bottom default-image--component-styles"><source media="(min-width: 1260px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/2Qa2uU2dOlp4nJlLAL5EMz/750fd141c488cb9f0ce790a0c9f02ef2/HI_RES_3r-section_3x.png?fit=pad&amp;q=66&amp;w=500&amp;fm=webp" type="image/webp"/><source media="(min-width: 1260px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/2Qa2uU2dOlp4nJlLAL5EMz/750fd141c488cb9f0ce790a0c9f02ef2/HI_RES_3r-section_3x.png?fit=pad&amp;q=66&amp;w=500" type="image/png"/><source media="(min-width: 1020px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/2Qa2uU2dOlp4nJlLAL5EMz/750fd141c488cb9f0ce790a0c9f02ef2/HI_RES_3r-section_3x.png?fit=pad&amp;q=66&amp;w=500&amp;fm=webp" type="image/webp"/><source media="(min-width: 1020px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/2Qa2uU2dOlp4nJlLAL5EMz/750fd141c488cb9f0ce790a0c9f02ef2/HI_RES_3r-section_3x.png?fit=pad&amp;q=66&amp;w=500" type="image/png"/><source media="(min-width: 720px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/2Qa2uU2dOlp4nJlLAL5EMz/750fd141c488cb9f0ce790a0c9f02ef2/HI_RES_3r-section_3x.png?fit=pad&amp;q=66&amp;w=500&amp;fm=webp" type="image/webp"/><source media="(min-width: 720px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/2Qa2uU2dOlp4nJlLAL5EMz/750fd141c488cb9f0ce790a0c9f02ef2/HI_RES_3r-section_3x.png?fit=pad&amp;q=66&amp;w=500" type="image/png"/><source media="(min-width: 375px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/2Qa2uU2dOlp4nJlLAL5EMz/750fd141c488cb9f0ce790a0c9f02ef2/HI_RES_3r-section_3x.png?fit=pad&amp;q=66&amp;w=500&amp;fm=webp" type="image/webp"/><source media="(min-width: 375px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/2Qa2uU2dOlp4nJlLAL5EMz/750fd141c488cb9f0ce790a0c9f02ef2/HI_RES_3r-section_3x.png?fit=pad&amp;q=66&amp;w=500" type="image/png"/><source media="(min-width: 360px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/2Qa2uU2dOlp4nJlLAL5EMz/750fd141c488cb9f0ce790a0c9f02ef2/HI_RES_3r-section_3x.png?fit=pad&amp;q=66&amp;w=500&amp;fm=webp" type="image/webp"/><source media="(min-width: 360px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/2Qa2uU2dOlp4nJlLAL5EMz/750fd141c488cb9f0ce790a0c9f02ef2/HI_RES_3r-section_3x.png?fit=pad&amp;q=66&amp;w=500" type="image/png"/><source media="(min-width: 320px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/2Qa2uU2dOlp4nJlLAL5EMz/750fd141c488cb9f0ce790a0c9f02ef2/HI_RES_3r-section_3x.png?fit=pad&amp;q=66&amp;w=500&amp;fm=webp" type="image/webp"/><source media="(min-width: 320px)" srcSet="//images.ctfassets.net/6at1y2gofdxy/2Qa2uU2dOlp4nJlLAL5EMz/750fd141c488cb9f0ce790a0c9f02ef2/HI_RES_3r-section_3x.png?fit=pad&amp;q=66&amp;w=500" type="image/png"/><img alt="Group of three people" class="animation-fade-in" loading="lazy" src="//images.ctfassets.net/6at1y2gofdxy/2Qa2uU2dOlp4nJlLAL5EMz/750fd141c488cb9f0ce790a0c9f02ef2/HI_RES_3r-section_3x.png?fit=pad&amp;q=66&amp;fm=webp&amp;w=500" data-testid="image"/></picture><div class="banner-fact-block--content banner-fact-block--content-left banner-fact-block--mobile-text-center"><h2 class="banner-fact-block--heading banner-fact-block--heading-large nv-markdown nv-markdown-inline">28%</h2><h3 class="banner-fact-block--subheading nv-markdown nv-markdown-inline">of patients with disease-causing (pathogenic) variants found in the highest-risk cancer genes had changes to medical management.<sup>1</sup></h3><div data-testid="fact-banner-body" class="banner-fact-block--body nv-markdown nv-body"><p>In the <em>JAMA Oncology</em> study, 1 in 4 patients with a high-risk positive genetic result received genetics-based personalized cancer care.<sup>1</sup></p></div></div></div></section><section class="icon-card-section--home-test-catalog-cards icon-card-section--gray icon-card-section--icon-card-section-root" id="12Mp85c7WG57sHi0wxaKMz" data-cy="section-sectionIconCards-9"><header class="nv-container base-heading--center base-heading--base-heading"><h2 class="nv-mh2 nv-markdown nv-markdown-inline">Test today for their tomorrow</h2></header><div 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groundbreaking research that helped show the life-changing potential of universal genetic testing for many cancer types.<sup>1</sup></h2><div class="banner-action-block--button-wrapper"><a class="nv-button nv-button-white" href="https://view.publitas.com/invitae/f400_intercept_study_overview/page/1" rel="noreferrer noopener" target="_blank"><span class="">View study summary</span></a></div></div></div></section><footer class="nv-container nv-fine-print-2 footnote-section--root" id="2TFq6bnGl2kJGeqEJ37tKh"><div class="nv-markdown nv-body"><p><strong>ASCO</strong>=American Society of Clinical Oncology<br/><strong>JAMA</strong>=Journal of the American Medical Association<br/></p><p><strong>References</strong></p><p><strong>1.</strong> Samadder NJ, <em>et al. JAMA Oncol.</em> 2021 Feb 1;7(2):230–237.<br/><strong>2.</strong> Walsh T, <em>et al. Proc Natl Acad Sci USA.</em> 2011;108(44):18032–18037.<br/><strong>3.</strong> Kurnit KC, <em>et al. Obstet Gynecol.</em> 2021;137(1):108–121.<br/><strong>4.</strong> Esplin ED, <em>et al. J Clin Oncol.</em> 2020;38(15_suppl):e16783-e16783.<br/><strong>5.</strong> Salo-Mullen EE, <em>et al. Cancer.</em> 2015;121(24):4382–4388.<br/><strong>6.</strong> Uson PLS Jr, <em>et al. Clin Transl Gastroenterol.</em> 2021 Oct 8;12(10):e00414.<br/><strong>7.</strong> Invitae data on file.<br/><strong>8.</strong> Whitworth PW, <em>et al. JAMA Network Open.</em> 2022;5(9).<br/><strong>9.</strong> Esplin ED, <em>et al. JCO Precis Oncol.</em> 2022;6:e2100516.<br/><strong>10.</strong> Kurian AW, <em>et al.</em> <em>JAMA.</em> 2023 Jul 3;330(1):43-51.</p></div></footer></main><footer class="global-footer--root" data-cy="footer_root"><div class="nv-container global-footer--footer-container"><div class="nv-grid global-footer--footer-content"><div class="nv-fine-print-1 global-footer--about global-footer--grid-child" data-cy="footer_logo"><svg aria-labelledby="invitae-logo-light-footer" height="54" role="img" viewBox="0 0 190 52" width="197" xmlns="http://www.w3.org/2000/svg"><title id="invitae-logo-light-footer">Invitae</title><path d="M67.3367 34.4077V17.3842H70.0417V34.4077H67.3367Z" fill="white"></path><path d="M123.746 34.4077V17.3842H126.451V34.4077H123.746Z" fill="white"></path><path d="M142.068 19.6203V34.3716H139.399V19.6203H133.339V17.3842H148.091V19.6203H142.068Z" fill="white"></path><path d="M173.302 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