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Life Science Posters | Tocris Bioscience
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leading experts in the field, and summarizing key areas of research, the following range of life science posters provide a colorful and informative source of information. We invite you to request* or download your copy today.</p> <p class="small">*Please note that Tocris will only send literature to established scientific business / institute addresses.</p> <hr> <div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/posters/fullsize/494370.jpg" data-toggle="lightbox" data-title="Addiction Life Science Poster" data-footer="<a href='/literature/literature-request/494370' rel='nofollow' title='Request copy of the Addiction Life Science Poster'>Request copy</a> or <a class=' pdf-download' href='https://resources.tocris.com/pdfs/literature/posters/addiction-poster-2016.pdf' download='https://resources.tocris.com/pdfs/literature/posters/addiction-poster-2016.pdf' target='_blank' rel='nofollow' title='Download PDF of the Addiction Life Science Poster' data-title='Addiction Life Science Poster'>Download PDF</a> today"><img src="https://resources.tocris.com/images/literature/posters/regular/494370.jpg" alt="Addiction Life Science Poster" class="img-fluid"></a> </div><!-- /lit_image --> <h3>Addiction</h3> <h4>Mechanisms of Addiction</h4> <p class="small">Prof David Nutt, Imperial College London</p> <p>The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.</p> <ul class="lit_buttons"> <li><a class="btn btn-quinary" href="/literature/literature-request/494370" rel="nofollow" title="Request copy of the Addiction Life Science Poster">Request copy</a></li> <li><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/addiction-poster-2016.pdf" download="https://resources.tocris.com/pdfs/literature/posters/addiction-poster-2016.pdf" target="_blank" rel="nofollow" title="Download PDF of the Addiction Life Science Poster" data-title="Addiction Life Science Poster">Download PDF<div class="lit_pdf"></div></a></li> </ul> </div><!-- /lit_content --></div><!-- /row lit_item --><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/posters/fullsize/636206.jpg" data-toggle="lightbox" data-title="Allosteric GPCR Pharmacology Life Science Poster" data-footer="<a href='/literature/literature-request/636206' rel='nofollow' title='Request copy of the Allosteric GPCR Pharmacology Life Science Poster'>Request copy</a> or <a class=' pdf-download' href='https://resources.tocris.com/pdfs/literature/posters/allosteric-gpcr-pharmacology-poster-2019.pdf' download='https://resources.tocris.com/pdfs/literature/posters/allosteric-gpcr-pharmacology-poster-2019.pdf' target='_blank' rel='nofollow' title='Download PDF of the Allosteric GPCR Pharmacology Life Science Poster' data-title='Allosteric GPCR Pharmacology Life Science Poster'>Download PDF</a> today"><img src="https://resources.tocris.com/images/literature/posters/regular/636206.jpg" alt="Allosteric GPCR Pharmacology Life Science Poster" class="img-fluid"></a> </div><!-- /lit_image --> <h3>Allosteric GPCR Pharmacology</h3> <p class="small">Arthur Christopoulos, David Thal, Denise Wootten and Patrick M. Sexton. Monash University</p> <p>G protein-coupled receptors (GPCRs) are intrinsically allosteric proteins. This poster provides insights into allosteric mechanisms of GPCR biology, highlighting key facets of GPCR allostery and therapeutic applications of allosteric modulators.</p> <ul class="lit_buttons"> <li><a class="btn btn-quinary" href="/literature/literature-request/636206" rel="nofollow" title="Request copy of the Allosteric GPCR Pharmacology Life Science Poster">Request copy</a></li> <li><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/allosteric-gpcr-pharmacology-poster-2019.pdf" download="https://resources.tocris.com/pdfs/literature/posters/allosteric-gpcr-pharmacology-poster-2019.pdf" target="_blank" rel="nofollow" title="Download PDF of the Allosteric GPCR Pharmacology Life Science Poster" data-title="Allosteric GPCR Pharmacology Life Science Poster">Download PDF<div class="lit_pdf"></div></a></li> </ul> </div><!-- /lit_content --></div><!-- /row lit_item --><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/posters/fullsize/244891.jpg?v=1" data-toggle="lightbox" data-title="Alzheimer's Disease Life Science Poster" data-footer="<a href='/literature/literature-request/244891' rel='nofollow' title='Request copy of the Alzheimer's Disease Life Science Poster'>Request copy</a> or <a class=' pdf-download' href='https://resources.tocris.com/pdfs/literature/posters/alzheimers-poster-2023.pdf' download='https://resources.tocris.com/pdfs/literature/posters/alzheimers-poster-2023.pdf' target='_blank' rel='nofollow' title='Download PDF of the Alzheimer's Disease Life Science Poster' data-title='Alzheimer's Disease Life Science Poster'>Download PDF</a> today"><img loading="lazy" src="https://resources.tocris.com/images/literature/posters/regular/244891.jpg?v=1" alt="Alzheimer's Disease Life Science Poster" class="img-fluid"></a> </div><!-- /lit_image --> <h3>Alzheimer's Disease</h3> <h4>Alzheimer's Disease Neuropathology and Epidemiology</h4> <p class="small">Dimitra Sokolova and Soyon Hong, University College London</p> <p>Alzheimer's disease (AD) is a debilitating and progressive neurodegenerative disease and the most common cause of dementia, affecting approximately 30% of individuals aged over 85 years. This poster summarizes the cellular and molecular mechanisms of AD.</p> <ul class="lit_buttons"> <li><a class="btn btn-quinary" href="/literature/literature-request/244891" rel="nofollow" title="Request copy of the Alzheimer's Disease Life Science Poster">Request copy</a></li> <li><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/alzheimers-poster-2023.pdf" download="https://resources.tocris.com/pdfs/literature/posters/alzheimers-poster-2023.pdf" target="_blank" rel="nofollow" title="Download PDF of the Alzheimer's Disease Life Science Poster" data-title="Alzheimer's Disease Life Science Poster">Download PDF<div class="lit_pdf"></div></a></li> </ul> </div><!-- /lit_content --></div><!-- /row lit_item --><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/posters/fullsize/525564.jpg?v=2" data-toggle="lightbox" data-title="Angiogenesis in Cancer Life Science Poster" data-footer="<a href='/literature/literature-request/525564' rel='nofollow' title='Request copy of the Angiogenesis in Cancer Life Science Poster'>Request copy</a> or <a class=' pdf-download' href='https://resources.tocris.com/pdfs/literature/posters/angiogenesis-cancer-2023-poster.pdf' download='https://resources.tocris.com/pdfs/literature/posters/angiogenesis-cancer-2023-poster.pdf' target='_blank' rel='nofollow' title='Download PDF of the Angiogenesis in Cancer Life Science Poster' data-title='Angiogenesis in Cancer Life Science Poster'>Download PDF</a> today"><img loading="lazy" src="https://resources.tocris.com/images/literature/posters/regular/525564.jpg?v=2" alt="Angiogenesis in Cancer Life Science Poster" class="img-fluid"></a> </div><!-- /lit_image --> <h3>Angiogenesis in Cancer</h3> <p>This poster summarizes the pathogenesis of angiogenesis in cancer, as well as some of the main angiogenesis therapeutic targets. </p> <ul class="lit_buttons"> <li><a class="btn btn-quinary" href="/literature/literature-request/525564" rel="nofollow" title="Request copy of the Angiogenesis in Cancer Life Science Poster">Request copy</a></li> <li><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/angiogenesis-cancer-2023-poster.pdf" download="https://resources.tocris.com/pdfs/literature/posters/angiogenesis-cancer-2023-poster.pdf" target="_blank" rel="nofollow" title="Download PDF of the Angiogenesis in Cancer Life Science Poster" data-title="Angiogenesis in Cancer Life Science Poster">Download PDF<div class="lit_pdf"></div></a></li> </ul> </div><!-- /lit_content --></div><!-- /row lit_item --><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/posters/fullsize/368180.jpg" data-toggle="lightbox" data-title="Autophagy Life Science Poster" data-footer="<a href='/literature/literature-request/368180' rel='nofollow' title='Request copy of the Autophagy Life Science Poster'>Request copy</a> or <a class=' pdf-download' href='https://resources.tocris.com/pdfs/literature/posters/autophagy-poster-2014.pdf' download='https://resources.tocris.com/pdfs/literature/posters/autophagy-poster-2014.pdf' target='_blank' rel='nofollow' title='Download PDF of the Autophagy Life Science Poster' data-title='Autophagy Life Science Poster'>Download PDF</a> today"><img loading="lazy" src="https://resources.tocris.com/images/literature/posters/regular/368180.jpg" alt="Autophagy Life Science Poster" class="img-fluid"></a> </div><!-- /lit_image --> <h3>Autophagy</h3> <h4>Autophagy: Mechanisms and Function</h4> <p class="small">Patricia Boya, CSIC<br>Patrice Codogno, University Paris-Descartes</p> <p>Autophagy is a cellular process used by cells for degradation and recycling. Written by Patricia Boya and Patrice Codogno, this poster summarizes the molecular machinery, physiology and pathology of autophagy. Compounds available from Tocris are listed.</p> <ul class="lit_buttons"> <li><a class="btn btn-quinary" href="/literature/literature-request/368180" rel="nofollow" title="Request copy of the Autophagy Life Science Poster">Request copy</a></li> <li><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/autophagy-poster-2014.pdf" download="https://resources.tocris.com/pdfs/literature/posters/autophagy-poster-2014.pdf" target="_blank" rel="nofollow" title="Download PDF of the Autophagy Life Science Poster" data-title="Autophagy Life Science Poster">Download PDF<div class="lit_pdf"></div></a></li> </ul> </div><!-- /lit_content --></div><!-- /row lit_item --><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/posters/fullsize/482944.jpg?v=1" data-toggle="lightbox" data-title="Cancer Metabolism Life Science Poster" data-footer="<a href='/literature/literature-request/482944' rel='nofollow' title='Request copy of the Cancer Metabolism Life Science Poster'>Request copy</a> or <a class=' pdf-download' href='https://resources.tocris.com/pdfs/literature/posters/cancer-metabolism-poster-2022.pdf' download='https://resources.tocris.com/pdfs/literature/posters/cancer-metabolism-poster-2022.pdf' target='_blank' rel='nofollow' title='Download PDF of the Cancer Metabolism Life Science Poster' data-title='Cancer Metabolism Life Science Poster'>Download PDF</a> today"><img loading="lazy" src="https://resources.tocris.com/images/literature/posters/regular/482944.jpg?v=1" alt="Cancer Metabolism Life Science Poster" class="img-fluid"></a> </div><!-- /lit_image --> <h3>Cancer Metabolism</h3> <p>This poster summarizes the main metabolic pathways in cancer cells and highlights potential targets for cancer therapeutics. Genetic changes and epigenetic modifications in cancer cells alter the regulation of cellular metabolic pathways providing potential cancer therapeutic targets.</p> <ul class="lit_buttons"> <li><a class="btn btn-quinary" href="/literature/literature-request/482944" rel="nofollow" title="Request copy of the Cancer Metabolism Life Science Poster">Request copy</a></li> <li><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/cancer-metabolism-poster-2022.pdf" download="https://resources.tocris.com/pdfs/literature/posters/cancer-metabolism-poster-2022.pdf" target="_blank" rel="nofollow" title="Download PDF of the Cancer Metabolism Life Science Poster" data-title="Cancer Metabolism Life Science Poster">Download PDF<div class="lit_pdf"></div></a></li> </ul> </div><!-- /lit_content --></div><!-- /row lit_item --><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/posters/fullsize/508457.jpg?v=2" data-toggle="lightbox" data-title="Cell Cycle & DNA Damage Repair Life Science Poster" data-footer="<a href='/literature/literature-request/508457' rel='nofollow' title='Request copy of the Cell Cycle & DNA Damage Repair Life Science Poster'>Request copy</a> or <a class=' pdf-download' href='https://resources.tocris.com/pdfs/literature/posters/cell-cycle-dna-poster-2023.pdf' download='https://resources.tocris.com/pdfs/literature/posters/cell-cycle-dna-poster-2023.pdf' target='_blank' rel='nofollow' title='Download PDF of the Cell Cycle & DNA Damage Repair Life Science Poster' data-title='Cell Cycle & DNA Damage Repair Life Science Poster'>Download PDF</a> today"><img loading="lazy" src="https://resources.tocris.com/images/literature/posters/regular/508457.jpg?v=2" alt="Cell Cycle & DNA Damage Repair Life Science Poster" class="img-fluid"></a> </div><!-- /lit_image --> <h3>Cell Cycle & DNA Damage Repair</h3> <p>In normal cells, each stage of the cell cycle is tightly regulated, however in cancer cells many genes and proteins that are involved in the regulation of the cell cycle are mutated or over expressed. This poster summarizes the stages of the cell cycle and DNA repair. It also highlights strategies for enhancing replicative stress in cancer cells to force mitotic catastrophe and cell death.</p> <ul class="lit_buttons"> <li><a class="btn btn-quinary" href="/literature/literature-request/508457" rel="nofollow" title="Request copy of the Cell Cycle & DNA Damage Repair Life Science Poster">Request copy</a></li> <li><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/cell-cycle-dna-poster-2023.pdf" download="https://resources.tocris.com/pdfs/literature/posters/cell-cycle-dna-poster-2023.pdf" target="_blank" rel="nofollow" title="Download PDF of the Cell Cycle & DNA Damage Repair Life Science Poster" data-title="Cell Cycle & DNA Damage Repair Life Science Poster">Download PDF<div class="lit_pdf"></div></a></li> </ul> </div><!-- /lit_content --></div><!-- /row lit_item --><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/posters/fullsize/234528.jpg" data-toggle="lightbox" data-title="Depression Life Science Poster" data-footer="<a href='/literature/literature-request/234528' rel='nofollow' title='Request copy of the Depression Life Science Poster'>Request copy</a> or <a class=' pdf-download' href='https://resources.tocris.com/pdfs/literature/posters/depression-poster-2015.pdf' download='https://resources.tocris.com/pdfs/literature/posters/depression-poster-2015.pdf' target='_blank' rel='nofollow' title='Download PDF of the Depression Life Science Poster' data-title='Depression Life Science Poster'>Download PDF</a> today"><img loading="lazy" src="https://resources.tocris.com/images/literature/posters/regular/234528.jpg" alt="Depression Life Science Poster" class="img-fluid"></a> </div><!-- /lit_image --> <h3>Depression</h3> <h4>Antidepressants - Current and Future Targets</h4> <p class="small">Phil Skolnick, National Institutes of Health<br>Piotr Popik, Jagiellonian University<br>Ramon Trullas, Consejo Superior de Investigaciones Científicas (CSIC)</p> <p>Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.</p> <ul class="lit_buttons"> <li><a class="btn btn-quinary" href="/literature/literature-request/234528" rel="nofollow" title="Request copy of the Depression Life Science Poster">Request copy</a></li> <li><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/depression-poster-2015.pdf" download="https://resources.tocris.com/pdfs/literature/posters/depression-poster-2015.pdf" target="_blank" rel="nofollow" title="Download PDF of the Depression Life Science Poster" data-title="Depression Life Science Poster">Download PDF<div class="lit_pdf"></div></a></li> </ul> </div><!-- /lit_content --></div><!-- /row lit_item --><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/posters/fullsize/482945.jpg?v=2" data-toggle="lightbox" data-title="Epigenetics in Cancer Life Science Poster" data-footer="<a href='/literature/literature-request/482945' rel='nofollow' title='Request copy of the Epigenetics in Cancer Life Science Poster'>Request copy</a> or <a class=' pdf-download' href='https://resources.tocris.com/pdfs/literature/posters/epigenetics-cancer-poster-2023.pdf' download='https://resources.tocris.com/pdfs/literature/posters/epigenetics-cancer-poster-2023.pdf' target='_blank' rel='nofollow' title='Download PDF of the Epigenetics in Cancer Life Science Poster' data-title='Epigenetics in Cancer Life Science Poster'>Download PDF</a> today"><img loading="lazy" src="https://resources.tocris.com/images/literature/posters/regular/482945.jpg?v=2" alt="Epigenetics in Cancer Life Science Poster" class="img-fluid"></a> </div><!-- /lit_image --> <h3>Epigenetics in Cancer</h3> <p>This poster summarizes the main epigenetic targets in cancer. The dysregulation of epigenetic modifications has been shown to result in oncogenesis and cancer progression. Unlike genetic mutations, epigenetic alterations are considered to be reversible and thus make promising therapeutic targets.</p> <ul class="lit_buttons"> <li><a class="btn btn-quinary" href="/literature/literature-request/482945" rel="nofollow" title="Request copy of the Epigenetics in Cancer Life Science Poster">Request copy</a></li> <li><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/epigenetics-cancer-poster-2023.pdf" download="https://resources.tocris.com/pdfs/literature/posters/epigenetics-cancer-poster-2023.pdf" target="_blank" rel="nofollow" title="Download PDF of the Epigenetics in Cancer Life Science Poster" data-title="Epigenetics in Cancer Life Science Poster">Download PDF<div class="lit_pdf"></div></a></li> </ul> </div><!-- /lit_content --></div><!-- /row lit_item --><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/posters/fullsize/629782.jpg" data-toggle="lightbox" data-title="GPCR Efficacy and Biased Agonism Life Science Poster" data-footer="<a href='/literature/literature-request/629782' rel='nofollow' title='Request copy of the GPCR Efficacy and Biased Agonism Life Science Poster'>Request copy</a> or <a class=' pdf-download' href='https://resources.tocris.com/pdfs/literature/posters/gpcr-efficacy-biased-agonism-poster-v1-2019.pdf' download='https://resources.tocris.com/pdfs/literature/posters/gpcr-efficacy-biased-agonism-poster-v1-2019.pdf' target='_blank' rel='nofollow' title='Download PDF of the GPCR Efficacy and Biased Agonism Life Science Poster' data-title='GPCR Efficacy and Biased Agonism Life Science Poster'>Download PDF</a> today"><img loading="lazy" src="https://resources.tocris.com/images/literature/posters/regular/629782.jpg" alt="GPCR Efficacy and Biased Agonism Life Science Poster" class="img-fluid"></a> </div><!-- /lit_image --> <h3>GPCR Efficacy and Biased Agonism</h3> <p class="small">Patrick M. Sexton, Arthur Christopoulos and Denise Wootten, Monash University and Fudan University</p> <p>GPCRs can interact with multiple distinct transducers or regulatory proteins and these can be preferentially engaged in an agonist-specific manner giving rise to biased agonism. This poster discusses cutting edge GPCR signaling pharmacology and highlights therapeutic applications of biased agonism.</p> <ul class="lit_buttons"> <li><a class="btn btn-quinary" href="/literature/literature-request/629782" rel="nofollow" title="Request copy of the GPCR Efficacy and Biased Agonism Life Science Poster">Request copy</a></li> <li><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/gpcr-efficacy-biased-agonism-poster-v1-2019.pdf" download="https://resources.tocris.com/pdfs/literature/posters/gpcr-efficacy-biased-agonism-poster-v1-2019.pdf" target="_blank" rel="nofollow" title="Download PDF of the GPCR Efficacy and Biased Agonism Life Science Poster" data-title="GPCR Efficacy and Biased Agonism Life Science Poster">Download PDF<div class="lit_pdf"></div></a></li> </ul> </div><!-- /lit_content --></div><!-- /row lit_item --><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/posters/fullsize/494492.jpg" data-toggle="lightbox" data-title="Gut Hormones Life Science Poster" data-footer="<a href='/literature/literature-request/494492' rel='nofollow' title='Request copy of the Gut Hormones Life Science Poster'>Request copy</a> or <a class=' pdf-download' href='https://resources.tocris.com/pdfs/literature/posters/gut-hormone-poster-2017.pdf' download='https://resources.tocris.com/pdfs/literature/posters/gut-hormone-poster-2017.pdf' target='_blank' rel='nofollow' title='Download PDF of the Gut Hormones Life Science Poster' data-title='Gut Hormones Life Science Poster'>Download PDF</a> today"><img loading="lazy" src="https://resources.tocris.com/images/literature/posters/regular/494492.jpg" alt="Gut Hormones Life Science Poster" class="img-fluid"></a> </div><!-- /lit_image --> <h3>Gut Hormones</h3> <h4>Gut Hormones and Metabolism</h4> <p class="small">Rebeccca Scott and Stephen R. Bloom, Imperial College London</p> <p>The gastrointestinal tract is the largest endocrine gland in the human body, secreting hormones that affect digestion, appetite and energy expenditure. Neuropeptide modulators and gut hormones that influence appetite are reviewed in this poster.</p> <ul class="lit_buttons"> <li><a class="btn btn-quinary" href="/literature/literature-request/494492" rel="nofollow" title="Request copy of the Gut Hormones Life Science Poster">Request copy</a></li> <li><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/gut-hormone-poster-2017.pdf" download="https://resources.tocris.com/pdfs/literature/posters/gut-hormone-poster-2017.pdf" target="_blank" rel="nofollow" title="Download PDF of the Gut Hormones Life Science Poster" data-title="Gut Hormones Life Science Poster">Download PDF<div class="lit_pdf"></div></a></li> </ul> </div><!-- /lit_content --></div><!-- /row lit_item --><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/posters/fullsize/499073.jpg?v=1" data-toggle="lightbox" data-title="Huntington's Disease Life Science Poster" data-footer="<a href='/literature/literature-request/499073' rel='nofollow' title='Request copy of the Huntington's Disease Life Science Poster'>Request copy</a> or <a class=' pdf-download' href='https://resources.tocris.com/pdfs/literature/posters/huntingtons-poster-2022.pdf' download='https://resources.tocris.com/pdfs/literature/posters/huntingtons-poster-2022.pdf' target='_blank' rel='nofollow' title='Download PDF of the Huntington's Disease Life Science Poster' data-title='Huntington's Disease Life Science Poster'>Download PDF</a> today"><img loading="lazy" src="https://resources.tocris.com/images/literature/posters/regular/499073.jpg?v=1" alt="Huntington's Disease Life Science Poster" class="img-fluid"></a> </div><!-- /lit_image --> <h3>Huntington's Disease</h3> <h4>Huntington's Disease: Pathophysiology and Clinical Prospects</h4> <p class="small">Nina Stöberl and Nicholas Allen, University of Cardiff</p> <p>Huntington's disease (HD) is a severe monogenic neurodegenerative disorder, which is characterized by the prevalent loss of GABAergic medium spiny neurons (MSN) in the striatum. This poster summarizes the effects of mutant huntingtin aggregation implicated in the pathology of HD, as well as highlighting the use of iPSCs for HD modeling.</p> <ul class="lit_buttons"> <li><a class="btn btn-quinary" href="/literature/literature-request/499073" rel="nofollow" title="Request copy of the Huntington's Disease Life Science Poster">Request copy</a></li> <li><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/huntingtons-poster-2022.pdf" download="https://resources.tocris.com/pdfs/literature/posters/huntingtons-poster-2022.pdf" target="_blank" rel="nofollow" title="Download PDF of the Huntington's Disease Life Science Poster" data-title="Huntington's Disease Life Science Poster">Download PDF<div class="lit_pdf"></div></a></li> </ul> </div><!-- /lit_content --></div><!-- /row lit_item --><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/posters/fullsize/494493.jpg" data-toggle="lightbox" data-title="Multiple Sclerosis Life Science Poster" data-footer="<a href='/literature/literature-request/494493' rel='nofollow' title='Request copy of the Multiple Sclerosis Life Science Poster'>Request copy</a> or <a class=' pdf-download' href='https://resources.tocris.com/pdfs/literature/posters/multiple-sclerosis-2016.pdf' download='https://resources.tocris.com/pdfs/literature/posters/multiple-sclerosis-2016.pdf' target='_blank' rel='nofollow' title='Download PDF of the Multiple Sclerosis Life Science Poster' data-title='Multiple Sclerosis Life Science Poster'>Download PDF</a> today"><img loading="lazy" src="https://resources.tocris.com/images/literature/posters/regular/494493.jpg" alt="Multiple Sclerosis Life Science Poster" class="img-fluid"></a> </div><!-- /lit_image --> <h3>Multiple Sclerosis</h3> <h4>Multiple Sclerosis: from Neurobiology to Therapy</h4> <p class="small">Alastair Wilkins and Richard Ibitoye</p> <p>Multiple sclerosis (MS) is an autoimmune disease that is characterized by focal demyelination and axon degeneration in the central nervous system. This poster summarizes the neurobiology and current therapies of MS.</p> <ul class="lit_buttons"> <li><a class="btn btn-quinary" href="/literature/literature-request/494493" rel="nofollow" title="Request copy of the Multiple Sclerosis Life Science Poster">Request copy</a></li> <li><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/multiple-sclerosis-2016.pdf" download="https://resources.tocris.com/pdfs/literature/posters/multiple-sclerosis-2016.pdf" target="_blank" rel="nofollow" title="Download PDF of the Multiple Sclerosis Life Science Poster" data-title="Multiple Sclerosis Life Science Poster">Download PDF<div class="lit_pdf"></div></a></li> </ul> </div><!-- /lit_content --></div><!-- /row lit_item --><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/posters/fullsize/234507.jpg?v=2" data-toggle="lightbox" data-title="Parkinson's Disease Life Science Poster" data-footer="<a href='/literature/literature-request/234507' rel='nofollow' title='Request copy of the Parkinson's Disease Life Science Poster'>Request copy</a> or <a class=' pdf-download' href='https://resources.tocris.com/pdfs/literature/posters/parkinsons-poster-2022.pdf' download='https://resources.tocris.com/pdfs/literature/posters/parkinsons-poster-2022.pdf' target='_blank' rel='nofollow' title='Download PDF of the Parkinson's Disease Life Science Poster' data-title='Parkinson's Disease Life Science Poster'>Download PDF</a> today"><img loading="lazy" src="https://resources.tocris.com/images/literature/posters/regular/234507.jpg?v=2" alt="Parkinson's Disease Life Science Poster" class="img-fluid"></a> </div><!-- /lit_image --> <h3>Parkinson's Disease</h3> <h4>Parkinson's Disease: Neurobiology and Therapeutic Strategies</h4> <p class="small">Anthony H.V. Schapira, University College London</p> <p>Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.</p> <ul class="lit_buttons"> <li><a class="btn btn-quinary" href="/literature/literature-request/234507" rel="nofollow" title="Request copy of the Parkinson's Disease Life Science Poster">Request copy</a></li> <li><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/parkinsons-poster-2022.pdf" download="https://resources.tocris.com/pdfs/literature/posters/parkinsons-poster-2022.pdf" target="_blank" rel="nofollow" title="Download PDF of the Parkinson's Disease Life Science Poster" data-title="Parkinson's Disease Life Science Poster">Download PDF<div class="lit_pdf"></div></a></li> </ul> </div><!-- /lit_content --></div><!-- /row lit_item --><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/posters/fullsize/234501.jpg" data-toggle="lightbox" data-title="Programmed Cell Death Life Science Poster" data-footer="<a href='/literature/literature-request/234501' rel='nofollow' title='Request copy of the Programmed Cell Death Life Science Poster'>Request copy</a> or <a class=' pdf-download' href='https://resources.tocris.com/pdfs/literature/posters/programmed-cell-death-poster-2014.pdf' download='https://resources.tocris.com/pdfs/literature/posters/programmed-cell-death-poster-2014.pdf' target='_blank' rel='nofollow' title='Download PDF of the Programmed Cell Death Life Science Poster' data-title='Programmed Cell Death Life Science Poster'>Download PDF</a> today"><img loading="lazy" src="https://resources.tocris.com/images/literature/posters/regular/234501.jpg" alt="Programmed Cell Death Life Science Poster" class="img-fluid"></a> </div><!-- /lit_image --> <h3>Programmed Cell Death</h3> <h4>Apoptosis, Necroptosis and Cell Survival</h4> <p class="small">Bram van Raam, Universiteit Gent<br>Guy Salvesen, Sanford-Burnham Medical Research Institute</p> <p>There are two currently recognized forms of programmed cell death: apoptosis and necroptosis. This poster summarizes the signaling pathways involved in apoptosis, necroptosis and cell survival following death receptor activation, and highlights the influence of the molecular switch, cFLIP, on cell fate.</p> <ul class="lit_buttons"> <li><a class="btn btn-quinary" href="/literature/literature-request/234501" rel="nofollow" title="Request copy of the Programmed Cell Death Life Science Poster">Request copy</a></li> <li><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/programmed-cell-death-poster-2014.pdf" download="https://resources.tocris.com/pdfs/literature/posters/programmed-cell-death-poster-2014.pdf" target="_blank" rel="nofollow" title="Download PDF of the Programmed Cell Death Life Science Poster" data-title="Programmed Cell Death Life Science Poster">Download PDF<div class="lit_pdf"></div></a></li> </ul> </div><!-- /lit_content --></div><!-- /row lit_item --><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/posters/fullsize/522525.jpg" data-toggle="lightbox" data-title="Rheumatoid Arthritis Life Science Poster" data-footer="<a href='/literature/literature-request/522525' rel='nofollow' title='Request copy of the Rheumatoid Arthritis Life Science Poster'>Request copy</a> or <a class=' pdf-download' href='https://resources.tocris.com/pdfs/literature/posters/rheumatoide-arthritis-poster-2016.pdf' download='https://resources.tocris.com/pdfs/literature/posters/rheumatoide-arthritis-poster-2016.pdf' target='_blank' rel='nofollow' title='Download PDF of the Rheumatoid Arthritis Life Science Poster' data-title='Rheumatoid Arthritis Life Science Poster'>Download PDF</a> today"><img loading="lazy" src="https://resources.tocris.com/images/literature/posters/regular/522525.jpg" alt="Rheumatoid Arthritis Life Science Poster" class="img-fluid"></a> </div><!-- /lit_image --> <h3>Rheumatoid Arthritis</h3> <h4>Epigenetic Drug Targets</h4> <p class="small">Adam P. Cribbs, Marc Feldmann and Udo Oppermann, University of Oxford</p> <p>Rheumatoid arthritis (RA) is a chronic destructive inflammatory autoimmune disease that results from a breakdown in immune tolerance, for reasons that are as yet unknown. This poster summarizes the pathology of RA and the inflammatory processes involved, as well as describing some of the epigenetic modifications associated with the disease and the potential for targeting these changes in the discovery of new treatments.</p> <ul class="lit_buttons"> <li><a class="btn btn-quinary" href="/literature/literature-request/522525" rel="nofollow" title="Request copy of the Rheumatoid Arthritis Life Science Poster">Request copy</a></li> <li><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/rheumatoide-arthritis-poster-2016.pdf" download="https://resources.tocris.com/pdfs/literature/posters/rheumatoide-arthritis-poster-2016.pdf" target="_blank" rel="nofollow" title="Download PDF of the Rheumatoid Arthritis Life Science Poster" data-title="Rheumatoid Arthritis Life Science Poster">Download PDF<div class="lit_pdf"></div></a></li> </ul> </div><!-- /lit_content --></div><!-- /row lit_item --><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/posters/fullsize/630620.jpg" data-toggle="lightbox" data-title="Stem Cell Workflow Life Science Poster" data-footer="<a href='/literature/literature-request/630620' rel='nofollow' title='Request copy of the Stem Cell Workflow Life Science Poster'>Request copy</a> or <a class=' pdf-download' href='https://resources.tocris.com/pdfs/literature/posters/stem-cell-workflow-poster-v1-2019.pdf' download='https://resources.tocris.com/pdfs/literature/posters/stem-cell-workflow-poster-v1-2019.pdf' target='_blank' rel='nofollow' title='Download PDF of the Stem Cell Workflow Life Science Poster' data-title='Stem Cell Workflow Life Science Poster'>Download PDF</a> today"><img loading="lazy" src="https://resources.tocris.com/images/literature/posters/regular/630620.jpg" alt="Stem Cell Workflow Life Science Poster" class="img-fluid"></a> </div><!-- /lit_image --> <h3>Stem Cell Workflow</h3> <h4>Using Small Molecules</h4> <p>Stem cells have potential as a source of cells and tissues for research and treatment of disease. This poster summarizes some key protocols demonstrating the use of small molecules across the stem cell workflow, from reprogramming, through self-renewal, storage and differentiation to verification. Advantages of using small molecules are also highlighted.</p> <ul class="lit_buttons"> <li><a class="btn btn-quinary" href="/literature/literature-request/630620" rel="nofollow" title="Request copy of the Stem Cell Workflow Life Science Poster">Request copy</a></li> <li><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/stem-cell-workflow-poster-v1-2019.pdf" download="https://resources.tocris.com/pdfs/literature/posters/stem-cell-workflow-poster-v1-2019.pdf" target="_blank" rel="nofollow" title="Download PDF of the Stem Cell Workflow Life Science Poster" data-title="Stem Cell Workflow Life Science Poster">Download PDF<div class="lit_pdf"></div></a></li> </ul> </div><!-- /lit_content --></div><!-- /row lit_item --><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/posters/fullsize/571184.jpg?v=2" data-toggle="lightbox" data-title="Stem Cells Life Science Poster" data-footer="<a href='/literature/literature-request/571184' rel='nofollow' title='Request copy of the Stem Cells Life Science Poster'>Request copy</a> or <a class=' pdf-download' href='https://resources.tocris.com/pdfs/literature/posters/stem-cell-differentiation-poster-2022.pdf' download='https://resources.tocris.com/pdfs/literature/posters/stem-cell-differentiation-poster-2022.pdf' target='_blank' rel='nofollow' title='Download PDF of the Stem Cells Life Science Poster' data-title='Stem Cells Life Science Poster'>Download PDF</a> today"><img loading="lazy" src="https://resources.tocris.com/images/literature/posters/regular/571184.jpg?v=2" alt="Stem Cells Life Science Poster" class="img-fluid"></a> </div><!-- /lit_image --> <h3>Stem Cells</h3> <h4>Stem Cells and Differentiation</h4> <p class="small">Rebecca Quelch and Stefan Przyborski</p> <p>Written by Rebecca Quelch and Stefan Przyborski from Durham University (UK), this poster describes the isolation of pluripotent stem cells, their maintenance in culture, differentiation, and the generation and potential uses of organoids.</p> <ul class="lit_buttons"> <li><a class="btn btn-quinary" href="/literature/literature-request/571184" rel="nofollow" title="Request copy of the Stem Cells Life Science Poster">Request copy</a></li> <li><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/stem-cell-differentiation-poster-2022.pdf" download="https://resources.tocris.com/pdfs/literature/posters/stem-cell-differentiation-poster-2022.pdf" target="_blank" rel="nofollow" title="Download PDF of the Stem Cells Life Science Poster" data-title="Stem Cells Life Science Poster">Download PDF<div class="lit_pdf"></div></a></li> </ul> </div><!-- /lit_content --></div><!-- /row lit_item --> </div> <div id="sidebar" class="col-xs-12 col-sm-4 col-md-3 col-lg-3 col-xl-3"> <div class="distributor_region"></div> </div> </section> <section id="block-block-16" class="block block-block clearfix"> 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