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The mRNA vaccine technology transfer hub

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<section class="sf-content content" id="content" role="main" tabindex="-1"> <div id="PageContent_TA51A0481002_Col00" class="sf_colsIn container" data-sf-element="Container" data-placeholder-label="Container"> <!--noindex--><!--stopindex--> <nav id="2853fa37f6a04b418d6e55916037396f" aria-label="You are here"> <ul class="sf-breadscrumb breadcrumb"> <li><a href="/">Home</a><span aria-hidden="true">/</span></li> <li><a href="/initiatives">Initiatives</a><span aria-hidden="true">/</span></li> <li class="active">The mRNA vaccine technology transfer hub</li> </ul> </nav> <!--/noindex--><!--startindex--> <script type="application/ld+json"> {"itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https://www.who.int","name":"Home"}},{"@type":"ListItem","position":2,"item":{"@id":"https://www.who.int/initiatives","name":"Initiatives"}},{"@type":"ListItem","position":3,"item":{"@id":"https://www.who.int/initiatives/the-mrna-vaccine-technology-transfer-hub","name":"The mRNA vaccine technology transfer hub"}}],"itemListOrder":"ItemListOrderAscending","@context":"http://schema.org","@type":"BreadcrumbList"} </script> </div> <div class="row" data-sf-element="Row"> <div id="PageContent_TA51A0481001_Col00" class="sf_colsIn col-md-12" data-sf-element="Column 1" data-placeholder-label="Body content"> <div class="hero-image--wrapper hero-image--high-wrapper high has-caption" data-url=""> <div class="inner responsive-background-image high-1790700141 bg-top-position"> <img sizes="(max-width: 768px) 200px, (max-width: 1024px) 700px, (max-width: 1366px) 1000px, 1920px" srcset="https://cdn.who.int/media/images/default-source/initiatives/10-11afrigen281rb0-1462-mincrop-min.tmb-768v.jpg?sfvrsn=3aefbdd0_7 768w, https://cdn.who.int/media/images/default-source/initiatives/10-11afrigen281rb0-1462-mincrop-min.tmb-1024v.jpg?sfvrsn=3aefbdd0_7 1024w, https://cdn.who.int/media/images/default-source/initiatives/10-11afrigen281rb0-1462-mincrop-min.tmb-1366v.jpg?sfvrsn=3aefbdd0_7 1366w, https://cdn.who.int/media/images/default-source/initiatives/10-11afrigen281rb0-1462-mincrop-min.tmb-1920v.jpg?sfvrsn=3aefbdd0_7 1920w" alt="The mRNA vaccine technology transfer hub" /> <div class="sf_colsIn container"> <div class="hero-image--content bg-text-light"> <p class="title"><span>The mRNA vaccine technology transfer hub</span></p> </div> </div> </div> <div class="sf-image-credit"> <div class="sf-image-credit__content"> <div class="sf-image-credit__inner"> Rodger Bosch </div> </div> <div class="sf-image-credit__label"> <span class="sf-image-credit__copyright">&copy;</span> <span class="sf-image-credit__text">Credits </span> <i class="icon plus-icon"></i> </div> </div> <script> var imageCreditClass = document.getElementsByClassName("sf-image-credit"); var preventFunction = function () { event.preventDefault() }; for (var i = 0; i < imageCreditClass.length; i++) { imageCreditClass[i].addEventListener('click', preventFunction);; } </script> </div> <div id="PageContent_C024_Col00" class="sf_colsIn container" data-sf-element="Container" data-placeholder-label="Container"><div class="row" data-sf-element="Row"> <div id="PageContent_C070_Col00" class="sf_colsIn col-md-1" data-sf-element="Column 1" data-placeholder-label="Column 1"> </div> <div id="PageContent_C070_Col01" class="sf_colsIn col-md-10" data-sf-element="Column 2" data-placeholder-label="Column 2"><div class="row" data-sf-element="Row"> <div id="PageContent_C048_Col00" class="sf_colsIn col-md-1" data-sf-element="Column 1" data-placeholder-label="Column 1"> </div> <div id="PageContent_C048_Col01" class="sf_colsIn col-md-10" data-sf-element="Column 2" data-placeholder-label="Column 2"><div class="row" data-sf-element="Row"> <div id="PageContent_C049_Col00" class="sf_colsIn col-md-1" data-sf-element="Column 1" data-placeholder-label="Column 1"> </div> <div id="PageContent_C049_Col01" class="sf_colsIn col-md-10" data-sf-element="Column 2" data-placeholder-label="Column 2"> <div class="sf-content-block content-block" > <div ><p>Announced on 21 June 2021, the objective of the technology transfer hub is to build capacity in low- and middle-income countries to produce mRNA vaccines through a centre of excellence and training (the mRNA vaccine technology hub). The hub is located at Afrigen, Cape Town, South Africa, and will work with a network of technology recipients (spokes) in low- and middle-income countries.&nbsp;<o:p></o:p></p><p><br /></p></div> </div> </div> <div id="PageContent_C049_Col02" class="sf_colsIn col-md-1" data-sf-element="Column 3" data-placeholder-label="Column 3"> </div> </div> </div> <div id="PageContent_C048_Col02" class="sf_colsIn col-md-1" data-sf-element="Column 3" data-placeholder-label="Column 3"> </div> </div> </div> <div id="PageContent_C070_Col02" class="sf_colsIn col-md-1" data-sf-element="Column 3" data-placeholder-label="Column 3"> </div> </div> </div> <div id="PageContent_C075_Col00" class="sf_colsIn background-widget bg-light-gray bg-image" data-sf-element="Background widget" data-placeholder-label="Background widget"><div id="PageContent_C076_Col00" class="sf_colsIn container" data-sf-element="Container" data-placeholder-label="Container"><div class="row" data-sf-element="Row"> <div id="PageContent_C077_Col00" class="sf_colsIn col-md-6" data-sf-element="Column 1" data-placeholder-label="Column 1"> <div class="section-heading"> <h2>How it will work</h2> </div> <div class="sf-content-block content-block" > <div ><p>Concretely, the Hub at Afrigen will share technology and technical know-how with local producers. WHO and partners will bring training and financial support to build the necessary human capital for production know-how, quality control and product regulation, and will assist where needed with the necessary licenses.<o:p></o:p></p><p>The Hub and partners create a global common good for the benefit of all by providing a range of services along the entire vaccine value chain. Recipients will be able to contribute to the global effort to increase local vaccine production capacity, and may sign agreements with producers or develop vaccines locally.<o:p></o:p></p></div> </div> </div> <div id="PageContent_C077_Col01" class="sf_colsIn col-md-6" data-sf-element="Column 2" data-placeholder-label="Column 2"> <div class="section-heading"> <p>Key achievements to date</p> </div> <div class="sf-content-block content-block" > <div ><ul><li>Launched in July 2021, the South African Hub at Afrigen is fully ready to operate, with the main equipment in place;</li><li>The first batches of COVID-19 mRNA vaccines have already been produced;</li><li>WHO, with the support of an expert group, has selected a number of beneficiaries in all regions to receive technology transfer on mRNA vaccines;</li><li>Specialized training will be provided through training centres and by WHO so that beneficiary countries can start producing safe and effective vaccines as soon as possible.</li></ul></div> </div> </div> </div> <div class="section-heading"> <p>Partners</p> </div> <div class="row" data-sf-element="Row"> <div id="PageContent_C078_Col00" class="sf_colsIn col-md-6" data-sf-element="Column 1" data-placeholder-label="Column 1"> <div class="sf-content-block content-block" > <div ><p>The initiative is supported by WHO, the Medicines Patent Pool and the Act-Accelerator/COVAX</p><p>The South African hub comprises Afrigen Biologics, the South African Medical Research Council (SAMRC) and Biovac, a South African vaccine producer. Within this consortium, Afrigen is the entity mandated to establish mRNA vaccine production technology, SAMRC is providing the research and Biovac is the first manufacturing spoke.&nbsp;<o:p></o:p></p></div> </div> </div> <div id="PageContent_C078_Col01" class="sf_colsIn col-md-6" data-sf-element="Column 2" data-placeholder-label="Column 2"> <div class="sf-image thumb"> <img class="lazy" data-src="https://cdn.who.int/media/images/default-source/initiatives/mrna_init_logos_partners.tmb-1920v.png?sfvrsn=f3fb1b5f_5" data-image="https://cdn.who.int/media/images/default-source/initiatives/mrna_init_logos_partners.tmb-1920v.png?sfvrsn=f3fb1b5f_5" title="Mrna_Init_logos_partners" /> </div> </div> </div> </div> </div> <div id="PageContent_C079_Col00" class="sf_colsIn container" data-sf-element="Container" data-placeholder-label="Container"><div class="row" data-sf-element="Row"> <div id="PageContent_C087_Col00" class="sf_colsIn col-md-8" data-sf-element="Column 1" data-placeholder-label="Column 1"> <div class="section-heading"> <h2>News</h2> </div> <div class="row" data-sf-element="Row"> <div id="PageContent_C088_Col00" class="sf_colsIn col-md-6" data-sf-element="Column 1" data-placeholder-label="Column 1"> <div class="list-view vertical-list"> <div class="list-view--item vertical-list-item vertical-list-item--hightlight-image"> <a href="https://www.who.int/news/item/20-04-2023-mrna-technology-transfer-programme-moves-to-the-next-phase-of-its-development" class="link-container" aria-label="mRNA Technology Transfer Programme moves to the next phase of its development" role="link"> <div class="thumb"> <div class="background-image" data-image="/images/default-source/departments/department-of-communications/img_1430.tmb-479v.jpg?Culture=en&amp;sfvrsn=ea0de54d_1" style="background-image: url('/images/default-source/departments/department-of-communications/img_1430.tmb-479v.jpg?Culture=en&amp;sfvrsn=ea0de54d_1')"></div> </div> <div class="info"> <div class="date"> <span class="timestamp">20 April 2023</span> <div class="sf-tags-list"> <div class="sf-tags-list-item">Statement</div> </div> </div> <p class="heading text-underline">mRNA Technology Transfer Programme moves to the next phase of its development</p> </div> </a> </div> </div> </div> <div id="PageContent_C088_Col01" class="sf_colsIn col-md-6" data-sf-element="Column 2" data-placeholder-label="Column 2"> <div class="mdc-card mdc-card--horizontal" role="article"> <div class="mdc-card__primary-action "> <a href="https://www.paho.org/en/news/24-3-2022-latin-american-manufacturers-complete-first-training-mrna-technology-bid-improve" class="link" rel="noopener" target="_self"> <div class="mdc-card__media"> <img src="/images/default-source/thumbnails-global/paho-mrna-hub.jpeg?sfvrsn=960bb78d_2" title="PAHO-mRNA-hub" alt="PAHO-mRNA-hub"> </div> <div class="card-media--item"> <div class="card-media-primary"> <div id="3a5fa21ab881410c9c8a96a086e9f559" class="item--title">Latin American manufacturers complete first training in mRNA technology in bid to improve regional vaccine production</div> <div class="item--subtitle"></div> </div> <div class="card-media-secondary"> <div class="item--abstract"> 24 March 2022 </div> </div> </div> </a> </div> </div> <div class="list-view vertical-list"> <div class="list-view--item vertical-list-item"> <a href="https://www.who.int/news/item/13-04-2022-ukraine-next-country-to-receive-technology-from-the-who-mrna-technology-transfer-hub" class="link-container" aria-label="Ukraine next country to receive technology from the WHO mRNA technology transfer hub" role="link"> <div class="info"> <div class="date"> <span class="timestamp">13 April 2022</span> <div class="sf-tags-list"> <div class="sf-tags-list-item">Departmental update</div> </div> </div> <p class="heading text-underline">Ukraine next country to receive technology from the WHO mRNA technology transfer hub</p> </div> </a> </div> <div class="list-view--item vertical-list-item"> <a href="https://www.who.int/news/item/31-03-2022-indian-manufacturer-new-recipient-of-mrna-technology-through-the-mrna-technology-transfer-hub" class="link-container" aria-label="Indian manufacturer new recipient of mRNA technology through the mRNA technology transfer hub" role="link"> <div class="info"> <div class="date"> <span class="timestamp">31 March 2022</span> <div class="sf-tags-list"> <div class="sf-tags-list-item">News release</div> </div> </div> <p class="heading text-underline">Indian manufacturer new recipient of mRNA technology through the mRNA technology transfer hub</p> </div> </a> </div> <div class="list-view--item vertical-list-item"> <a href="https://www.who.int/news/item/23-02-2022-moving-forward-on-goal-to-boost-local-pharmaceutical-production-who-establishes-global-biomanufacturing-training-hub-in-republic-of-korea" class="link-container" aria-label="Moving forward on goal to boost local pharmaceutical production, WHO establishes global biomanufacturing training hub in Republic of Korea" role="link"> <div class="info"> <div class="date"> <span class="timestamp">23 February 2022</span> <div class="sf-tags-list"> <div class="sf-tags-list-item">News release</div> </div> </div> <p class="heading text-underline">Moving forward on goal to boost local pharmaceutical production, WHO establishes global biomanufacturing training hub in Republic of Korea</p> </div> </a> </div> <div class="list-view--item vertical-list-item"> <a href="https://www.who.int/news/item/18-02-2022-who-announces-first-technology-recipients-of-mrna-vaccine-hub-with-strong-support-from-african-and-european-partners" class="link-container" aria-label="WHO announces first technology recipients of mRNA vaccine hub with strong support from African and European partners" role="link"> <div class="info"> <div class="date"> <span class="timestamp">18 February 2022</span> <div class="sf-tags-list"> <div class="sf-tags-list-item">News release</div> </div> </div> <p class="heading text-underline">WHO announces first technology recipients of mRNA vaccine hub with strong support from African and European partners</p> </div> </a> </div> <div class="list-view--item vertical-list-item"> <a href="https://www.who.int/news/item/21-06-2021-who-supporting-south-african-consortium-to-establish-first-covid-mrna-vaccine-technology-transfer-hub" class="link-container" aria-label="WHO supporting South African consortium to establish first COVID mRNA vaccine technology transfer hub" role="link"> <div class="info"> <div class="date"> <span class="timestamp">21 June 2021</span> <div class="sf-tags-list"> <div class="sf-tags-list-item">News release</div> </div> </div> <p class="heading text-underline">WHO supporting South African consortium to establish first COVID mRNA vaccine technology transfer hub</p> </div> </a> </div> </div> </div> </div> </div> <div id="PageContent_C087_Col01" class="sf_colsIn col-md-4" data-sf-element="Column 2" data-placeholder-label="Column 2"> <div class="section-heading"> <h2>Related Links</h2> </div> <div class="mdc-card mdc-card--horizontal" role="article"> <div class="mdc-card__primary-action "> <a href="/initiatives/the-mrna-vaccine-technology-transfer-hub/faq" class="link" rel="noopener" target="_self"> <div class="card-media--item"> <div class="card-media-primary"> <div id="b1d5af4f26e94e8c869835bf7b5d3057" class="item--title">FAQ - The mRNA vaccine technology transfer hub</div> <div class="item--subtitle"></div> </div> <div class="card-media-secondary"> </div> </div> </a> </div> </div> <div class="mdc-card mdc-card--horizontal" role="article"> <div class="mdc-card__primary-action "> <a href="/initiatives/the-mrna-vaccine-technology-transfer-hub/recipients-of-mrna-technology-from-the-who-mrna-technology-transfer-hub" class="link" rel="noopener" target="_self"> <div class="card-media--item"> <div class="card-media-primary"> <div id="b575705b7ff14202baa536083b8a6a74" class="item--title">Full list of mRNA technology recipients</div> <div class="item--subtitle"></div> </div> <div class="card-media-secondary"> </div> </div> </a> </div> </div> <div class="section-heading"> <h2>Expression of interest</h2> </div> <div class="list-view vertical-list"> <div class="list-view--item vertical-list-item"> <a href="https://www.who.int/news-room/articles-detail/biologics-development---manufacturing---introductory-course-on-standard-practice-(gxp)-available-for-the-biomanufacturing-workforce" class="link-container" aria-label="Biologics Development &amp; Manufacturing - Introductory course on standard practice (GxP) available for the biomanufacturing workforce" role="link"> <div class="info"> <div class="date"> <span class="timestamp">11 May 2023</span> <div class="sf-tags-list"> <div class="sf-tags-list-item">Call for submissions</div> </div> </div> <p class="heading text-underline">Biologics Development &amp; Manufacturing - Introductory course on standard practice (GxP) available for the biomanufacturing workforce</p> </div> </a> </div> <div class="list-view--item vertical-list-item"> <a href="https://www.who.int/news-room/articles-detail/establishment-of-a-covid-19-mrna-vaccine-technology-transfer-hub-to-scale-up-global-manufacturing" class="link-container" aria-label="Establishment of a COVID-19 mRNA vaccine technology transfer hub to scale up global manufacturing" role="link"> <div class="info"> <div class="date"> <span class="timestamp">16 April 2021</span> <div class="sf-tags-list"> <div class="sf-tags-list-item">Expression of interest</div> </div> </div> <p class="heading text-underline">Establishment of a COVID-19 mRNA vaccine technology transfer hub to scale up global manufacturing</p> </div> </a> </div> </div> <div class="section-heading"> <p>Events</p> </div> <div class="list-view vertical-list sf-events-wrapper sf-events-list"> <div class="list-view--item vertical-list-item"> <a href="https://www.who.int/news-room/events/detail/2024/03/18/default-calendar/who-mpp-mrna-r-d-consortia-in-south-east-asia" class="link-container table event-table" aria-label="WHO/MPP mRNA R&amp;D consortia in South East Asia" role="link"> <div class="table-cell info"> <span class="timestamp"> <i class="fa fa-calendar" aria-hidden="true"></i> 18 – 19 March 2024 </span> <p class="heading text-underline">WHO/MPP mRNA R&amp;D consortia in South East Asia</p> </div> </a> </div> <div class="list-view--item vertical-list-item"> <a href="https://www.who.int/news-room/events/detail/2023/10/31/default-calendar/who-mpp-regional-mrna-meeting-in-searo-wpro" class="link-container table event-table" aria-label="WHO/MPP regional mRNA meeting in SEARO/WPRO" role="link"> <div class="table-cell info"> <span class="timestamp"> <i class="fa fa-calendar" aria-hidden="true"></i> 31 October – 1 November 2023 </span> <p class="heading text-underline">WHO/MPP regional mRNA meeting in SEARO/WPRO</p> </div> </a> </div> <div class="list-view--item vertical-list-item"> <a href="https://www.who.int/news-room/events/detail/2023/04/17/default-calendar/who-mpp-mrna-technology-transfer-programme-17-21-april-2023" class="link-container table event-table" aria-label="WHO/MPP mRNA Technology Transfer Programme" role="link"> <div class="table-cell info"> <span class="timestamp"> <i class="fa fa-calendar" aria-hidden="true"></i> 17 – 21 April 2023 </span> <p class="heading text-underline">WHO/MPP mRNA Technology Transfer Programme</p> </div> </a> </div> </div> </div> </div> <div class="row" data-sf-element="Row"> <div id="PageContent_C071_Col00" class="sf_colsIn col-md-4" data-sf-element="Column 1" data-placeholder-label="Column 1"> </div> <div id="PageContent_C071_Col01" class="sf_colsIn col-md-4" data-sf-element="Column 2" data-placeholder-label="Column 2"> </div> <div id="PageContent_C071_Col02" class="sf_colsIn col-md-4" data-sf-element="Column 3" data-placeholder-label="Column 3"> </div> </div> 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