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Search results for: acidic environment
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</div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: acidic environment</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9222</span> Different Methods Anthocyanins Extracted from Saffron</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hashem%20Barati">Hashem Barati</a>, <a href="https://publications.waset.org/abstracts/search?q=Afshin%20Farahbakhsh"> Afshin Farahbakhsh </a> </p> <p class="card-text"><strong>Abstract:</strong></p> The flowers of saffron contain anthocyanins. Generally, extraction of anthocyanins takes place at low temperatures (below 30 °C), preferably under vacuum (to minimize degradation) and in an acidic environment. In order to extract anthocyanins, the dried petals were added to 30 ml of acidic ethanol (pH=2). Amount of petals, extraction time, temperature, and ethanol percentage which were selected. Total anthocyanin content was a function of both variables of ethanol percent and extraction time.To prepare SW with pH of 3.5, different concentrations of 100, 400, 700, 1,000, and 2,000 ppm of sodium metabisulfite were added to aqueous sodium citrate. At this selected concentration, different extraction times of 20, 40, 60, 120, 180 min were tested to determine the optimum extraction time. When the extraction time was extended from 20 to 60 min, the total recovered anthocyanins of sulfur method changed from 650 to 710 mg/100 g. In the EW method Cellubrix and Pectinex enzymes were added separately to the buffer solution at different concentrations of 1%, 2.5%, 5%, 7%, 10%, and 12.5% and held for 2 hours reaction time at an ambient temperature of 40 °C. There was a considerable and significant difference in trends of Acys content of tepals extracted by pectinex enzymes at 5% concentration and AE solution. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=saffron" title="saffron">saffron</a>, <a href="https://publications.waset.org/abstracts/search?q=anthocyanins" title=" anthocyanins"> anthocyanins</a>, <a href="https://publications.waset.org/abstracts/search?q=acidic%20environment" title=" acidic environment"> acidic environment</a>, <a href="https://publications.waset.org/abstracts/search?q=acidic%20ethanol" title=" acidic ethanol"> acidic ethanol</a>, <a href="https://publications.waset.org/abstracts/search?q=pectinex%20enzymes" title=" pectinex enzymes"> pectinex enzymes</a>, <a href="https://publications.waset.org/abstracts/search?q=Cellubrix%20enzymes" title=" Cellubrix enzymes"> Cellubrix enzymes</a>, <a href="https://publications.waset.org/abstracts/search?q=sodium%20metabisulfite" title=" sodium metabisulfite"> sodium metabisulfite</a> </p> <a href="https://publications.waset.org/abstracts/48478/different-methods-anthocyanins-extracted-from-saffron" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/48478.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">513</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9221</span> Characteristic Composition and Sensory Contributions of Acidic Aroma in Mainstream Cigarette Smoke of Cherry-Red Tobacco</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Tian%20Yangyang">Tian Yangyang</a>, <a href="https://publications.waset.org/abstracts/search?q=Xu%20Zihe"> Xu Zihe</a>, <a href="https://publications.waset.org/abstracts/search?q=Lu%20Junping"> Lu Junping</a>, <a href="https://publications.waset.org/abstracts/search?q=Yang%20Jizhou"> Yang Jizhou</a>, <a href="https://publications.waset.org/abstracts/search?q=Xu%20Yiqun"> Xu Yiqun</a>, <a href="https://publications.waset.org/abstracts/search?q=Wang%20Jiansong"> Wang Jiansong</a>, <a href="https://publications.waset.org/abstracts/search?q=Chen%20Chao"> Chen Chao</a>, <a href="https://publications.waset.org/abstracts/search?q=Yang%20Mengmeng"> Yang Mengmeng</a>, <a href="https://publications.waset.org/abstracts/search?q=Guo%20Jianhua"> Guo Jianhua</a>, <a href="https://publications.waset.org/abstracts/search?q=Mu%20Wenjun"> Mu Wenjun</a>, <a href="https://publications.waset.org/abstracts/search?q=Wang%20Guiyao"> Wang Guiyao</a>, <a href="https://publications.waset.org/abstracts/search?q=Xue%20Chaoqun"> Xue Chaoqun</a>, <a href="https://publications.waset.org/abstracts/search?q=Liang%20Taibo"> Liang Taibo</a>, <a href="https://publications.waset.org/abstracts/search?q=Hu%20Liwei"> Hu Liwei</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Cherry-red tobacco is receiving constant attention from cigarette enterprises because of its special flavor. This study aims to explore the material basis for the formation of the characteristic flavor of cherry-red tobacco and to clarify the distribution characteristics of the acidic aroma component groups in its mainstream smoke. In order to reach the aims of current study, this study employs GC/MS to examine the differences of distribution characteristics in particulate matter of mainstream cigarette smoke between cherry-red and common tobacco, meanwhile the aroma activity values (OVA) was used to compare the contribution of acidic aroma of cherry-red tobacco. The results showed that: 1) Isovaleric acid, acetic acid and butyric acid were the key acidic components in the mainstream smoke of the samples, followed by 3-methylvaleric acid, 4-methylvaleric acid and n-valeric acid. 2)Analysis of the release of these key sour fragrance components showed that the acidic aroma of "YUN 85" mainstream smoke was stronger than the leaf group, cherry-red tobacco was the weakest. In addition, aging had the effect of reducing the acidic components of cherry-red tobacco and the addition of cherry-red tobacco had little effect on the acidic components of the original leaf group. 3) For 14 acidic aroma(OAV>1) in smoke of cherry-red tobacco, 3-methylpentanoic acid, 4-methylpentanoic acid, pentanoic acid, and isovaleric acid were very prominent in contributing to acidic aroma, while pyruvic acid, 2-methylbutyric acid, hydrogenated acid, and propionic acid were less contribution. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cherry-red%20tobacco" title="cherry-red tobacco">cherry-red tobacco</a>, <a href="https://publications.waset.org/abstracts/search?q=acidic%20aroma" title=" acidic aroma"> acidic aroma</a>, <a href="https://publications.waset.org/abstracts/search?q=GC%2FMS" title=" GC/MS"> GC/MS</a>, <a href="https://publications.waset.org/abstracts/search?q=mainstream%20cigarette%20smoke" title=" mainstream cigarette smoke"> mainstream cigarette smoke</a>, <a href="https://publications.waset.org/abstracts/search?q=odor%20activity%20value" title=" odor activity value"> odor activity value</a> </p> <a href="https://publications.waset.org/abstracts/157217/characteristic-composition-and-sensory-contributions-of-acidic-aroma-in-mainstream-cigarette-smoke-of-cherry-red-tobacco" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/157217.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">136</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9220</span> Modulation of Receptor-Activation Due to Hydrogen Bond Formation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sourav%20Ray">Sourav Ray</a>, <a href="https://publications.waset.org/abstracts/search?q=Christoph%20Stein"> Christoph Stein</a>, <a href="https://publications.waset.org/abstracts/search?q=Marcus%20Weber"> Marcus Weber</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A new class of drug candidates, initially derived from mathematical modeling of ligand-receptor interactions, activate the μ-opioid receptor (MOR) preferentially at acidic extracellular pH-levels, as present in injured tissues. This is of commercial interest because it may preclude the adverse effects of conventional MOR agonists like fentanyl, which include but are not limited to addiction, constipation, sedation, and apnea. Animal studies indicate the importance of taking the pH value of the chemical environment of MOR into account when designing new drugs. Hydrogen bonds (HBs) play a crucial role in stabilizing protein secondary structure and molecular interaction, such as ligand-protein interaction. These bonds may depend on the pH value of the chemical environment. For the MOR, antagonist naloxone and agonist [D-Ala2,N-Me-Phe4,Gly5-ol]-enkephalin (DAMGO) form HBs with ionizable residue HIS 297 at physiological pH to modulate signaling. However, such interactions were markedly reduced at acidic pH. Although fentanyl-induced signaling is also diminished at acidic pH, HBs with HIS 297 residue are not observed at either acidic or physiological pH for this strong agonist of the MOR. Molecular dynamics (MD) simulations can provide greater insight into the interaction between the ligand of interest and the HIS 297 residue. Amino acid protonation states are adjusted to the model difference in system acidity. Unbiased and unrestrained MD simulations were performed, with the ligand in the proximity of the HIS 297 residue. Ligand-receptor complexes were embedded in 1-palmitoyl-2-oleoyl-sn glycero-3-phosphatidylcholine (POPC) bilayer to mimic the membrane environment. The occurrence of HBs between the different ligands and the HIS 297 residue of MOR at acidic and physiological pH values were tracked across the various simulation trajectories. No HB formation was observed between fentanyl and HIS 297 residue at either acidic or physiological pH. Naloxone formed some HBs with HIS 297 at pH 5, but no such HBs were noted at pH 7. Interestingly, DAMGO displayed an opposite yet more pronounced HB formation trend compared to naloxone. Whereas a marginal number of HBs could be observed at even pH 5, HBs with HIS 297 were more stable and widely present at pH 7. The HB formation plays no and marginal role in the interaction of fentanyl and naloxone, respectively, with the HIS 297 residue of MOR. However, HBs play a significant role in the DAMGO and HIS 297 interaction. Post DAMGO administration, these HBs might be crucial for the remediation of opioid tolerance and restoration of opioid sensitivity. Although experimental studies concur with our observations regarding the influence of HB formation on the fentanyl and DAMGO interaction with HIS 297, the same could not be conclusively stated for naloxone. Therefore, some other supplementary interactions might be responsible for the modulation of the MOR activity by naloxone binding at pH 7 but not at pH 5. Further elucidation of the mechanism of naloxone action on the MOR could assist in the formulation of cost-effective naloxone-based treatment of opioid overdose or opioid-induced side effects. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=effect%20of%20system%20acidity" title="effect of system acidity">effect of system acidity</a>, <a href="https://publications.waset.org/abstracts/search?q=hydrogen%20bond%20formation" title=" hydrogen bond formation"> hydrogen bond formation</a>, <a href="https://publications.waset.org/abstracts/search?q=opioid%20action" title=" opioid action"> opioid action</a>, <a href="https://publications.waset.org/abstracts/search?q=receptor%20activation" title=" receptor activation"> receptor activation</a> </p> <a href="https://publications.waset.org/abstracts/138936/modulation-of-receptor-activation-due-to-hydrogen-bond-formation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/138936.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">175</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9219</span> The Effect of Solution pH of Chitosan on Antimicrobial Properties of Nylon 6,6 Fabrics</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nil%C3%BCfer%20Y%C4%B1ld%C4%B1z%20Varan">Nilüfer Yıldız Varan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The antimicrobial activities of chitosan against various bacteria and fungi are well known, and the antimicrobial activity of chitosan depends on pH. This study investigates the antimicrobial activity at different pH levels. Nylon 6,6 fabrics were treated with different chitosan solutions. Additionally, samples were treated also in basic conditions to see the antimicrobial activities. AATCC Test Method 100 was followed to evaluate the antimicrobial activity using Staphylococcus aureus ATCC 6538 test inoculum. The pH of the chitosan solutions was controlled below 6.5 since chitosan shows its antimicrobial activity only in acidic conditions because of its poor solubility above 6.5. In basic conditions, the samples did not show any antimicrobial activity. It appears from SEM images that the bonded chitosan in the structures exists. In acidic media (ph < 6.5), all samples showed antimicrobial activity. No correlation was found between pH levels and antimicrobial activity in acidic media. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=chitosan" title="chitosan">chitosan</a>, <a href="https://publications.waset.org/abstracts/search?q=nylon%206" title=" nylon 6"> nylon 6</a>, <a href="https://publications.waset.org/abstracts/search?q=6" title="6">6</a>, <a href="https://publications.waset.org/abstracts/search?q=crosslinking" title=" crosslinking"> crosslinking</a>, <a href="https://publications.waset.org/abstracts/search?q=pH%20stability" title=" pH stability"> pH stability</a>, <a href="https://publications.waset.org/abstracts/search?q=antimicrobial" title=" antimicrobial"> antimicrobial</a> </p> <a href="https://publications.waset.org/abstracts/74096/the-effect-of-solution-ph-of-chitosan-on-antimicrobial-properties-of-nylon-66-fabrics" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/74096.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">219</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9218</span> Effect of UV Radiation to Change the Properties of the Composite PA+GF</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Lenka%20Markovi%C4%8Dov%C3%A1">Lenka Markovičová</a>, <a href="https://publications.waset.org/abstracts/search?q=Viera%20Zatkal%C3%ADkov%C3%A1"> Viera Zatkalíková</a>, <a href="https://publications.waset.org/abstracts/search?q=Tomasz%20Garbacz"> Tomasz Garbacz</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The development of composite materials and the related design and manufacturing technologies is one of the most important advances in the history of materials. Composites are multifunctional materials having unprecedented mechanical and physical properties that can be tailored to meet the requirements of a particular application. Some composites also exhibit great resistance to high-temperature corrosion, oxidation, and wear. Polymers are widely used indoors and outdoors, therefore they are exposed to a chemical environment which may include atmospheric oxygen, acidic fumes, acidic rain, moisture heat and thermal shock, ultra-violet light, high energy radiation, etc. Different polymers are affected differently by these factors even though the amorphous polymers are more sensitive. Ageing is also important and it is defined as the process of deterioration of engineering materials resulting from the combined effects of atmospheric radiation, heat, oxygen, water, micro-organisms and other atmospheric factors. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=composites%20with%20glass%20fibers" title="composites with glass fibers">composites with glass fibers</a>, <a href="https://publications.waset.org/abstracts/search?q=mechanical%20properties" title=" mechanical properties"> mechanical properties</a>, <a href="https://publications.waset.org/abstracts/search?q=polyamides" title=" polyamides"> polyamides</a>, <a href="https://publications.waset.org/abstracts/search?q=UV%20degradation" title=" UV degradation"> UV degradation</a> </p> <a href="https://publications.waset.org/abstracts/31313/effect-of-uv-radiation-to-change-the-properties-of-the-composite-pagf" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/31313.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">288</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9217</span> Preparation of Magnetothermally Responsive Polymer Multilayer Films for Controlled Release Applications from Surfaces</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Eda%20Cagli">Eda Cagli</a>, <a href="https://publications.waset.org/abstracts/search?q=Irem%20Erel%20Goktepe"> Irem Erel Goktepe</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Externally triggered and effective release of therapeutics from polymer nanoplatforms is one of the key issues in cancer treatment. In this study, we aim to prepare polymer multilayer films which are stable at physiological conditions (little or no drug release) but release drug molecules at acidic pH and via application of AC magnetic field. First, novel stimuli responsive diblock copolymers composed of pH- and temperature-responsive blocks were synthesized. Then, block copolymer micelles with pH-responsive core and temperature responsive coronae will be obtained via pH-induced self-assembly of these block copolymers in aqueous environment. A model anticancer drug, e.g. Doxorubicin will be loaded in the micellar cores. Second, superparamagnetic nanoparticles will be synthesized. Magnetic nanoparticles and drug loaded block copolymer micelles will be used as building blocks to construct the multilayers. To mimic the acidic nature of the tumor tissues, Doxorubicin release from the micellar cores will be induced at acidic conditions. Moreover, Doxorubicin release from the multilayers will be facilitated via magnetothermal trigger. Application of AC magnetic field will induce the heating of magnetic nanoparticles resulting in an increase in the temperature of the polymer platform. This increase in temperature is expected to trigger conformational changes on the temperature-responsive micelle coronae and facilitate the release of Doxorubicin from the surface. Such polymer platform may find use in biomedical applications. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=layer-by-layer%20films" title="layer-by-layer films">layer-by-layer films</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetothermal%20trigger" title=" magnetothermal trigger"> magnetothermal trigger</a>, <a href="https://publications.waset.org/abstracts/search?q=smart%20polymers" title=" smart polymers"> smart polymers</a>, <a href="https://publications.waset.org/abstracts/search?q=stimuli%20responsive" title=" stimuli responsive"> stimuli responsive</a> </p> <a href="https://publications.waset.org/abstracts/44684/preparation-of-magnetothermally-responsive-polymer-multilayer-films-for-controlled-release-applications-from-surfaces" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/44684.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">364</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9216</span> Effect of the pH on the Degradation Kinetics of Biodegradable Mg-0.8Ca Orthopedic Implants</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=A.%20Mohamed">A. Mohamed</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20El-Aziz"> A. El-Aziz</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The pH of the body plays a great role in the degradation kinetics of biodegradable Mg-Ca orthopedic implants. At the location of fracture, the pH of the body becomes no longer neutral which draws the attention towards studying a range of different pH values of the body fluid. In this study, the pH of Hank’s balanced salt solution (HBSS) was modified by phosphate buffers into an aggressive acidic pH 1.8, a slightly acidic pH 5.3 and an alkaline pH 8.1. The biodegradation of Mg-0.8Ca implant was tested in those three different media using immersion test and electrochemical polarization means. It was proposed that the degradation rate has increased with decreasing the pH of HBSS. The immersion test revealed weight gain for all the samples followed by weight loss as the immersion time increased. The highest weight gain was pronounced for the acidic pH 1.8 and the least weight gain was observed for the alkaline pH 8.1. This was in agreement with the electrochemical polarization test results where the degradation rate was found to be high (7.29 ± 2.2 mm/year) in the aggressive acidic solution of pH 1.8 and relatively minimum (0.31 ± 0.06 mm/year) in the alkaline medium of pH 8.1. Furthermore, it was confirmed that the pH of HBSS has reached a steady state of an alkaline pH (~pH 11) at the end of the two-month immersion period regardless of the initial pH of the solution. Finally, the corrosion products formed on the samples’ surface were investigated by SEM, EDX and XRD analyses that revealed the formation of magnesium and calcium phosphates with different morphologies according to the pH. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biodegradable" title="biodegradable">biodegradable</a>, <a href="https://publications.waset.org/abstracts/search?q=electrochemical%20polarization%20means" title=" electrochemical polarization means"> electrochemical polarization means</a>, <a href="https://publications.waset.org/abstracts/search?q=orthopedics" title=" orthopedics"> orthopedics</a>, <a href="https://publications.waset.org/abstracts/search?q=immersion%20test" title=" immersion test"> immersion test</a>, <a href="https://publications.waset.org/abstracts/search?q=simulated%20body%20fluid" title=" simulated body fluid"> simulated body fluid</a> </p> <a href="https://publications.waset.org/abstracts/104188/effect-of-the-ph-on-the-degradation-kinetics-of-biodegradable-mg-08ca-orthopedic-implants" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/104188.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">123</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9215</span> The Impact of Low-Concentrated Acidic Electrolyzed Water on Foodborne Pathogens</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ewa%20Brychcy">Ewa Brychcy</a>, <a href="https://publications.waset.org/abstracts/search?q=Natalia%20Ulbin-Figlewicz"> Natalia Ulbin-Figlewicz</a>, <a href="https://publications.waset.org/abstracts/search?q=Dominika%20Kulig"> Dominika Kulig</a>, <a href="https://publications.waset.org/abstracts/search?q=%C5%BBaneta%20Kr%C3%B3l"> Żaneta Król</a>, <a href="https://publications.waset.org/abstracts/search?q=Andrzej%20Jarmoluk"> Andrzej Jarmoluk</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Acidic electrolyzed water (AEW) is an alternative with environmentally friendly broad spectrum microbial decontamination. It is produced by membrane electrolysis of a dilute NaCl solution in water ionizers. The aim of the study was to evaluate the effectiveness of low-concentrated AEW in reducing selected foodborne pathogens and to examine its bactericidal effect on cellular structures of Escherichia coli. E. coli and S. aureus cells were undetectable after 10 minutes of contact with electrolyzed salt solutions. Non-electrolyzed solutions did not inhibit the growth of bacteria. AE water was found to destroy the cellular structures of the E. coli. The use of more concentrated salt solutions and prolonged electrolysis time from 5 to 10 minutes resulted in a greater changes of rods shape as compared to the control and non-electrolyzed NaCl solutions. This research showed that low-concentrated acid electrolyzed water is an effective method to significantly reduce pathogenic microorganisms and indicated its potential application for decontamination of meat. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=acidic%20electrolyzed%20water" title="acidic electrolyzed water">acidic electrolyzed water</a>, <a href="https://publications.waset.org/abstracts/search?q=foodborne%20pathogens" title=" foodborne pathogens"> foodborne pathogens</a>, <a href="https://publications.waset.org/abstracts/search?q=meat%20decontamination" title=" meat decontamination"> meat decontamination</a>, <a href="https://publications.waset.org/abstracts/search?q=membrane%20electrolysis" title=" membrane electrolysis"> membrane electrolysis</a> </p> <a href="https://publications.waset.org/abstracts/7517/the-impact-of-low-concentrated-acidic-electrolyzed-water-on-foodborne-pathogens" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/7517.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">493</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9214</span> Shell Lime: An Eco-Friendly and Cost-Efficient Alternative for Agricultural Lime</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hene%20L.%20Hapinat">Hene L. Hapinat</a>, <a href="https://publications.waset.org/abstracts/search?q=Mae%20D.%20Dumapig"> Mae D. Dumapig</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study aimed to determine the lime potential of 3 mollusks, namely: Crassostrea iredalei (Oyster shell), Turritella terebra (Turret shell), and Anodontia edentula (Mangrove clam shell) as alternative for commercially produced agricultural lime. The hydrogen ion concentration (pH) and the lime concentration using Calcium Carbonate Equivalent (CCE) of each shellfish species were measured and tested for the enhancement of an acidic soil. The experiment was laid out in a Completely Randomized Design (CRD) with 4 treatments replicated 3 times. The treatments were as follows: Treatment A- 100 g agricultural lime; B- 100 g oyster shell lime; C- 100 g turret shell lime; and D- 100 g mangrove clam shell lime. Each treatment was combined to the acidic soil sample. The results were statistically analyzed using One-way Analysis of Variance (ANOVA) and Least Square Difference (LSD) at 0.01 and 0.05 levels of significance. Results revealed that lime produced from the 3 selected mollusks can be a potential source of alternative and/or supplement materials for agricultural lime in dealing with soil acidity, entailing lower cost of farm production. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=shell%20lime" title="shell lime">shell lime</a>, <a href="https://publications.waset.org/abstracts/search?q=pH" title=" pH"> pH</a>, <a href="https://publications.waset.org/abstracts/search?q=calcium%20carbonate%20concentrations" title=" calcium carbonate concentrations"> calcium carbonate concentrations</a>, <a href="https://publications.waset.org/abstracts/search?q=mollusks" title=" mollusks"> mollusks</a>, <a href="https://publications.waset.org/abstracts/search?q=agricultural%20lime" title=" agricultural lime"> agricultural lime</a>, <a href="https://publications.waset.org/abstracts/search?q=lime%20potential%20concentration" title=" lime potential concentration"> lime potential concentration</a>, <a href="https://publications.waset.org/abstracts/search?q=acidic%20soil" title=" acidic soil "> acidic soil </a> </p> <a href="https://publications.waset.org/abstracts/16781/shell-lime-an-eco-friendly-and-cost-efficient-alternative-for-agricultural-lime" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/16781.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">312</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9213</span> Impact of Ocean Acidification on Gene Expression Dynamics during Development of the Sea Urchin Species Heliocidaris erythrogramma</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hannah%20R.%20Devens">Hannah R. Devens</a>, <a href="https://publications.waset.org/abstracts/search?q=Phillip%20L.%20Davidson"> Phillip L. Davidson</a>, <a href="https://publications.waset.org/abstracts/search?q=Dione%20Deaker"> Dione Deaker</a>, <a href="https://publications.waset.org/abstracts/search?q=Kathryn%20E.%20Smith"> Kathryn E. Smith</a>, <a href="https://publications.waset.org/abstracts/search?q=Gregory%20A.%20Wray"> Gregory A. Wray</a>, <a href="https://publications.waset.org/abstracts/search?q=Maria%20Byrne"> Maria Byrne</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Marine invertebrate species with calcifying larvae are especially vulnerable to ocean acidification (OA) caused by rising atmospheric CO₂ levels. Acidic conditions can delay development, suppress metabolism, and decrease the availability of carbonate ions in the ocean environment for skeletogenesis. These stresses often result in increased larval mortality, which may lead to significant ecological consequences including alterations to the larval settlement, population distribution, and genetic connectivity. Importantly, many of these physiological and developmental effects are caused by genetic and molecular level changes. Although many studies have examined the effect of near-future oceanic pH levels on gene expression in marine invertebrates, little is known about the impact of OA on gene expression in a developmental context. Here, we performed mRNA-sequencing to investigate the impact of environmental acidity on gene expression across three developmental stages in the sea urchin Heliocidaris erythrogramma. We collected RNA from gastrula, early larva, and 1-day post-metamorphic juvenile sea urchins cultured at present-day and predicted future oceanic pH levels (pH 8.1 and 7.7, respectively). We assembled an annotated reference transcriptome encompassing development from egg to ten days post-metamorphosis by combining these data with datasets from two previous developmental transcriptomic studies of H. erythrogramma. Differential gene expression and time course analyses between pH conditions revealed significant alterations to developmental transcription that are potentially associated with pH stress. Consistent with previous investigations, genes involved in biomineralization and ion transport were significantly upregulated under acidic conditions. Differences in gene expression between the two pH conditions became more pronounced post-metamorphosis, suggesting a development-dependent effect of OA on gene expression. Furthermore, many differences in gene expression later in development appeared to be a result of broad downregulation at pH 7.7: of 539 genes differentially expressed at the juvenile stage, 519 of these were lower in the acidic condition. Time course comparisons between pH 8.1 and 7.7 samples also demonstrated over 500 genes were more lowly expressed in pH 7.7 samples throughout development. Of the genes exhibiting stage-dependent expression level changes, over 15% of these diverged from the expected temporal pattern of expression in the acidic condition. Through these analyses, we identify novel candidate genes involved in development, metabolism, and transcriptional regulation that are possibly affected by pH stress. Our results demonstrate that pH stress significantly alters gene expression dynamics throughout development. A large number of genes differentially expressed between pH conditions in juveniles relative to earlier stages may be attributed to the effects of acidity on transcriptional regulation, as a greater proportion of mRNA at this later stage has been nascent transcribed rather than maternally loaded. Also, the overall downregulation of many genes in the acidic condition suggests that OA-induced developmental delay manifests as suppressed mRNA expression, possibly from lower transcription rates or increased mRNA degradation in the acidic environment. Further studies will be necessary to determine in greater detail the extent of OA effects on early developing marine invertebrates. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=development" title="development">development</a>, <a href="https://publications.waset.org/abstracts/search?q=gene%20expression" title=" gene expression"> gene expression</a>, <a href="https://publications.waset.org/abstracts/search?q=ocean%20acidification" title=" ocean acidification"> ocean acidification</a>, <a href="https://publications.waset.org/abstracts/search?q=RNA-sequencing" title=" RNA-sequencing"> RNA-sequencing</a>, <a href="https://publications.waset.org/abstracts/search?q=sea%20urchins" title=" sea urchins"> sea urchins</a> </p> <a href="https://publications.waset.org/abstracts/98537/impact-of-ocean-acidification-on-gene-expression-dynamics-during-development-of-the-sea-urchin-species-heliocidaris-erythrogramma" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/98537.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">168</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9212</span> Computer Simulations of Stress Corrosion Studies of Quartz Particulate Reinforced ZA-27 Metal Matrix Composites</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=K.%20Vinutha">K. Vinutha</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The stress corrosion resistance of ZA-27 / TiO2 metal matrix composites (MMC’s) in high temperature acidic media has been evaluated using an autoclave. The liquid melt metallurgy technique using vortex method was used to fabricate MMC’s. TiO2 particulates of 50-80 µm in size are added to the matrix. ZA-27 containing 2,4,6 weight percentage of TiO2 are prepared. Stress corrosion tests were conducted by weight loss method for different exposure time, normality and temperature of the acidic medium. The corrosion rates of composites were lower to that of matrix ZA-27 alloy under all conditions. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=autoclave" title="autoclave">autoclave</a>, <a href="https://publications.waset.org/abstracts/search?q=MMC%E2%80%99s" title=" MMC’s"> MMC’s</a>, <a href="https://publications.waset.org/abstracts/search?q=stress%20corrosion" title=" stress corrosion"> stress corrosion</a>, <a href="https://publications.waset.org/abstracts/search?q=vortex%20method" title=" vortex method"> vortex method</a> </p> <a href="https://publications.waset.org/abstracts/28848/computer-simulations-of-stress-corrosion-studies-of-quartz-particulate-reinforced-za-27-metal-matrix-composites" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/28848.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">476</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9211</span> Performance of a Lytic Bacteriophage Cocktail against Pseudomonas aeruginosa in Conditions That Simulate the Cystic Fibrosis Lung Environment</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Isaac%20Martin">Isaac Martin</a>, <a href="https://publications.waset.org/abstracts/search?q=Abigail%20Lark"> Abigail Lark</a>, <a href="https://publications.waset.org/abstracts/search?q=Sandra%20Morales"> Sandra Morales</a>, <a href="https://publications.waset.org/abstracts/search?q=Eric%20W.%20Alton"> Eric W. Alton</a>, <a href="https://publications.waset.org/abstracts/search?q=Jane%20C.%20Davies"> Jane C. Davies</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objectives: The cystic fibrosis (CF) lung is a unique microbiological niche, wherein harmful bacteria persist for many years despite antibiotic therapy. Pseudomonas aeruginosa (Pa), the major culprit leading to lung decline and increased mortality, thrives in the lungs of patients with CF due to several factors that have been linked with poor antibiotic performance. Our group is investigating alternative therapies including bacteriophage cocktails with which we have previously demonstrated efficacy against planktonic organisms. In this study, we explored the effects of a 4-phage cocktail on Pa grown in two different conditions, intended to mirror the CF lung: a) alongside standard antibiotic treatment in pre-formed biofilms (structures formed by Pa-secreted exopolysaccharides which provide both physical and cell division barriers to antimicrobials and host defenses and b) in an acidic environment postulated to be present in the CF airway due both to the primary defect in bicarbonate secretion and secondary effects of inflammation. Methods: 16 Pa strains from CF patients at the Royal Brompton Hospital were selected based on sensitivity to a) ceftazidime/ tobramycin and b) the phage cocktail in a conventional plaque assay. To assess efficacy of phage in biofilms, 96 well plates with Pa (5x10⁷ CFU/ ml) were incubated in static conditions, allowing adherent bacterial colonies to form for 24 hr. Ceftazidime and tobramycin (both at 2 × MIC) were added, +/- bacteriophage (4x10⁸ PFU/mL) for a further 24 hr. Cell viability and biomass were estimated using fluorescent resazurin and crystal violet assays, respectively. To evaluate the effect of pH, strains were grown planktonically in shaking 96 well plates at pH 6.0, 6.6, 7.0 and 7.5 with tobramycin or phage, at varying concentrations. Cell viability was quantified by fluorescent resazurin assay. Results: For the biofilm assay, treatment groups were compared with untreated controls and expressed as percent reduction in cell viability and biomass. Addition of the 4-phage cocktail resulted in a 1.3-fold reduction in cell viability and 1.7-fold reduction in biomass (p < 0.001) when compared to standard antibiotic treatment alone. Notably, there was a 50 ± 15% reduction in cell viability and 60 ± 12% reduction in biomass (95% CI) for the 4 biofilms demonstrating the most resistance to antibiotic treatment. 83% of strains tested (n=6) showed decreased bacterial killing by tobramycin at acidic pHs (p < 0.01). However, 25% of strains (n=12) showed improved phage killing at acidic pHs (p < 0.05), with none showing the pattern of reduced efficacy at acidic pH demonstrated by tobramycin. Conclusion: The 4-phage anti-Pa cocktail tested against Pa performs well in pre-formed biofilms and in acidic environments; two conditions intended to mimic the CF lung. To our knowledge, these are the first data looking at the effects of subtle pH changes on phage-mediated bacterial killing in the context of Pa infection. These findings contribute to a growing body of evidence supporting the use of nebulised lytic bacteriophage as a treatment in the context of lung infection. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biofilm" title="biofilm">biofilm</a>, <a href="https://publications.waset.org/abstracts/search?q=cystic%20fibrosis" title=" cystic fibrosis"> cystic fibrosis</a>, <a href="https://publications.waset.org/abstracts/search?q=pH" title=" pH"> pH</a>, <a href="https://publications.waset.org/abstracts/search?q=Pseudomonas%20aeruginosa" title=" Pseudomonas aeruginosa"> Pseudomonas aeruginosa</a>, <a href="https://publications.waset.org/abstracts/search?q=lytic%20bacteriophage" title=" lytic bacteriophage"> lytic bacteriophage</a> </p> <a href="https://publications.waset.org/abstracts/80548/performance-of-a-lytic-bacteriophage-cocktail-against-pseudomonas-aeruginosa-in-conditions-that-simulate-the-cystic-fibrosis-lung-environment" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/80548.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">173</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9210</span> Studies of Heavy Metal Ions Removal Efficiency in the Presence of Anionic Surfactant Using Ion Exchangers</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Anna%20Wolowicz">Anna Wolowicz</a>, <a href="https://publications.waset.org/abstracts/search?q=Katarzyna%20Staszak"> Katarzyna Staszak</a>, <a href="https://publications.waset.org/abstracts/search?q=Zbigniew%20Hubicki"> Zbigniew Hubicki</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Nowadays heavy metal ions as well as surfactants are widely used throughout the world due to their useful properties. The consequence of such widespread use is their significant production. On the other hand, the increasing demand for surfactants and heavy metal ions results in production of large amounts of wastewaters which are discharged to the environment from mining, metal plating, pharmaceutical, cosmetic, fertilizer, paper, pesticide and electronic industries, pigments producing, petroleum refining and from autocatalyst, fibers, food, polymer industries etc. Heavy metal ions are non-biodegradable in the environment, cable of accumulation in living organisms and organs, toxic and carcinogenic. On the other hand, not only heavy metal ions but also surfactants affect the purity of water and soils. Some of surfactants are also toxic, harmful and dangerous because they are able to penetrate into surface waters causing foaming, blocked diffusion of oxygen from the atmosphere and act as emulsifiers of hydrophobic substances and increase solubility of many the dangerous pollutants. Among surfactants the anionic ones dominate and their share in the global production of surfactants is around 50 ÷ 60%. Due to the negative impact of heavy metals and surfactants on aquatic ecosystems and living organisms, removal and monitoring of their concentration in the environment is extremely important. Surfactants and heavy metal ions removal can be achieved by different biological and physicochemical methods. The adsorption as well as the ion-exchange methods play here a significant role. The aim of this study was heavy metal ions removal from aqueous solutions using different types of ion exchangers in the presence of anionic surfactants. Preliminary studies of copper(II), nickel(II), zinc(II) and cobalt(II) removal from acidic solutions using ion exchangers (Lewatit MonoPlus TP 220, Lewatit MonoPlus SR 7, Purolite A 400 TL, Purolite A 830, Purolite S 984, Dowex PSR 2, Dowex PSR3, Lewatit AF-5) allowed to select the most effective ones for the above mentioned sorbates and then to checking their removal efficiency in the presence of anionic surfactants. As it was found out Lewatit MonoPlus TP 220 of the chelating type, show the highest sorption capacities for copper(II) ions in comparison with the other ion exchangers under discussion, e.g. 9.98 mg/g (0.1 M HCl); 9.12 mg/g (6 M HCl). Moreover, cobalt(II) removal efficiency was the highest in 0.1 M HCl using also Lewatit MonoPlus TP 220 (6.9 mg/g) similar to zinc(II) (9.1 mg/g) and nickiel(II) (6.2 mg/g). As the anionic surfactant sodium dodecyl sulphate (SDS) was used and surfactant parameters such as viscosity (η), density (ρ) and critical micelle concentration (CMC) were obtained: η = 1.13 ± 0,01 mPa·s; ρ = 999.76 mg/cm3; CMC = 2.26 g/cm3. The studies of copper(II) removal from acidic solutions in the presence of SDS of different concentration show negligible effects on copper(II) removal efficiency. The sorption capacity of Cu(II) from 0.1 M acidic solution of 500 mg/L initial concentration was equal to 46.8 mg/g whereas in the presence of SDS 45.3 mg/g (0.1 mg SDS/L), 47.1 mg/g (0.5 mg SDS/L), 46.6 mg/g (1 mg SDS/L). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=anionic%20surfactant" title="anionic surfactant">anionic surfactant</a>, <a href="https://publications.waset.org/abstracts/search?q=heavy%20metal%20ions" title=" heavy metal ions"> heavy metal ions</a>, <a href="https://publications.waset.org/abstracts/search?q=ion%20exchanger" title=" ion exchanger"> ion exchanger</a>, <a href="https://publications.waset.org/abstracts/search?q=removal" title=" removal"> removal</a> </p> <a href="https://publications.waset.org/abstracts/89510/studies-of-heavy-metal-ions-removal-efficiency-in-the-presence-of-anionic-surfactant-using-ion-exchangers" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/89510.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">142</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9209</span> Acid-Responsive Polymer Conjugates as a New Generation of Corrosion Protecting Materials </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Naruphorn%20Dararatana">Naruphorn Dararatana</a>, <a href="https://publications.waset.org/abstracts/search?q=Farzad%20Seidi"> Farzad Seidi</a>, <a href="https://publications.waset.org/abstracts/search?q=Daniel%20Crespy"> Daniel Crespy</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Protection of metals is a critical issue in industry. The annual cost of corrosion in the world is estimated to be about 2.5 trillion dollars and continuously increases. Therefore, there is a need for developing novel protection approaches to improve corrosion protection. We designed and synthesized smart polymer/corrosion inhibitor conjugates as new generations of corrosion protecting materials. Firstly, a polymerizable acrylate derivative of 8-hydroxyquinoline (8HQ), an effective corrosion inhibitor, containing acid-labile β-thiopropionate linkage was prepared in three steps. Then, it was copolymerized with ethyl acrylate in the presence of 1,1′-azobis(cyclohexanecarbonitrile) (ABCN) by radical polymerization. Nanoparticles with an average diameter of 140 nm were prepared from the polymer conjugate by the miniemulsion-solvent evaporation process. The release behavior of 8HQ from the the nanoparticles was studied in acidic (pH 3.5) and neutral media (pH 7.0). The release profile showed a faster release of 8HQ in acidic medium in comparison with neutral medium. Indeed 100% of 8HQ was released after 14 days in acidic medium whereas only around 15% of 8HQ was released during the same period at neutral pH. Therefore, the polymer conjugate nanoparticles are suitable materials as additives or to form coatings on metal substrates for corrosion protection. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Corrosion%20inhibitor" title="Corrosion inhibitor">Corrosion inhibitor</a>, <a href="https://publications.waset.org/abstracts/search?q=8-Hydroxyquinoline" title=" 8-Hydroxyquinoline"> 8-Hydroxyquinoline</a>, <a href="https://publications.waset.org/abstracts/search?q=Polymer%20conjugated" title=" Polymer conjugated"> Polymer conjugated</a>, <a href="https://publications.waset.org/abstracts/search?q=%CE%B2-Thiopropionate" title=" β-Thiopropionate"> β-Thiopropionate</a> </p> <a href="https://publications.waset.org/abstracts/80403/acid-responsive-polymer-conjugates-as-a-new-generation-of-corrosion-protecting-materials" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/80403.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">192</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9208</span> Selection of Indigenous Tree Species and Microbial Inoculation for the Restoration of Degraded Uplands</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nelly%20S.%20Aggangan">Nelly S. Aggangan</a>, <a href="https://publications.waset.org/abstracts/search?q=Julieta%20A.%20Anarna"> Julieta A. Anarna</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Indigenous tree species are priority planting materials for the National Greening Program of the Department of Environment and Natural Resources. Areas for reforestation are marginal grasslands where plant growth is stunted and seedling survival is low. This experiment was conducted to compare growth rates and seedling survival of seven indigenous reforestation species. Narra (Pterocarpus indicus), salago (Wikstroemia lanceolata), kisubeng (Sapindus saponaria), tuai (Biscofia javanica), batino (Alstonia macrophylla), bani (Pongamina pinnata) and ipil (Intsia bijuga) were inoculated with Mykovam® (mycorrhizal fungi) and Bio-N® (N2-fixing bacteria) during pricking. After five months in the nursery, the treated seedlings were planted in degraded upland acidic red soil in Cavinti, Laguna (Luzon). During outplanting, all mycorrhiza inoculated seedlings had 50-80% mycorrhizal roots while the control ones had 5-10% mycorrhizal roots. Mykovam increased height of narra, salago and kisubeng. Stem diameter was bigger in mycorrhizal salago than the control. After two years in the field, Mykovam®+Bio-N® inoculated narra, salago and bani gave 95% survival while non-mycorrhizal tuai gave the lowest survival (25%). Inoculated seedlings grew faster than the control. Highest height increase was in batino (103%), followed by bani (95%), ipil (59%), narra (58%), tuai (53%) and kisubeng was the lowest (10%). Stem diameter was increased by Mykovam® from 13-39% over the control. Highest stem diameter was obtained from narra (50%), followed by bani (40%), batino (36%), ipil (33%), salago (28%), kisubeng and tuai (12%) had the lowest. In conclusion, Mykovam® inoculated batino, bani, narra, salago and ipil can be selected to restore degraded upland acidic red soil in the Philippines. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Azospirillum%20spp." title="Azospirillum spp.">Azospirillum spp.</a>, <a href="https://publications.waset.org/abstracts/search?q=Bio-N%C2%AE" title=" Bio-N®"> Bio-N®</a>, <a href="https://publications.waset.org/abstracts/search?q=Mykovam%C2%AE" title=" Mykovam®"> Mykovam®</a>, <a href="https://publications.waset.org/abstracts/search?q=nitrogen%20fixing%20bacteria" title=" nitrogen fixing bacteria"> nitrogen fixing bacteria</a>, <a href="https://publications.waset.org/abstracts/search?q=acidic%20red%20soil" title=" acidic red soil "> acidic red soil </a> </p> <a href="https://publications.waset.org/abstracts/44484/selection-of-indigenous-tree-species-and-microbial-inoculation-for-the-restoration-of-degraded-uplands" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/44484.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">309</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9207</span> Meticulous Doxorubicin Release from pH-Responsive Nanoparticles Entrapped within an Injectable Thermoresponsive Depot </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Huayang%20Yu">Huayang Yu</a>, <a href="https://publications.waset.org/abstracts/search?q=Nicola%20Ingram"> Nicola Ingram</a>, <a href="https://publications.waset.org/abstracts/search?q=David%20C.%20Green"> David C. Green</a>, <a href="https://publications.waset.org/abstracts/search?q=Paul%20D.%20Thornton"> Paul D. Thornton</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The dual stimuli-controlled release of doxorubicin from gel-embedded nanoparticles is reported. Non-cytotoxic polymer nanoparticles are formed from poly(ethylene glycol)-b-poly(benzyl glutamate) that, uniquely, contain a central ester link. This connection renders the nanoparticles pH-responsive, enabling extensive doxorubicin release in acidic solutions (pH 6.5), but not in solutions of physiological pH (pH 7.4). Doxorubicin loaded nanoparticles were found to be stable for at least 31 days and lethal against the three breast cancer cell lines tested. Furthermore, doxorubicin-loaded nanoparticles could be incorporated within a thermoresponsive poly(2-hydroxypropyl methacrylate) gel depot, which forms immediately upon injection of poly(2-hydroxypropyl methacrylate) into aqueous solution. The combination of the poly(2-hydroxypropyl methacrylate) gel and poly(ethylene glycol)-b-poly(benzyl glutamate) nanoparticles yields an injectable doxorubicin delivery system that facilities near-complete drug release when maintained at elevated temperatures (37 °C) in acidic solution (pH 6.5). In contrast, negligible payload release occurs when the material is stored at room temperature in a non-acidic solution (pH 7.4). The system has great potential as a vehicle for the prolonged, site-specific release of chemotherapeutics. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biodegradable" title="biodegradable">biodegradable</a>, <a href="https://publications.waset.org/abstracts/search?q=nanoparticle" title=" nanoparticle"> nanoparticle</a>, <a href="https://publications.waset.org/abstracts/search?q=polymer" title=" polymer"> polymer</a>, <a href="https://publications.waset.org/abstracts/search?q=thermoresponsive" title=" thermoresponsive"> thermoresponsive</a> </p> <a href="https://publications.waset.org/abstracts/123917/meticulous-doxorubicin-release-from-ph-responsive-nanoparticles-entrapped-within-an-injectable-thermoresponsive-depot" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/123917.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">136</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9206</span> Preparation and Characterization of Calcium Phosphate Cement</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=W.%20Thepsuwan">W. Thepsuwan</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Monmaturapoj"> N. Monmaturapoj</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Calcium phosphate cements (CPCs) is one of the most attractive bioceramics due to its moldable and shape ability to fill complicated bony cavities or small dental defect positions. In this study, CPCs were produced by using mixtures of tetracalcium phosphate (TTCP, Ca4O(PO4)2) and dicalcium phosphate anhydrous (DCPA, CaHPO4) in equimolar ratio (1/1) with aqueous solutions of acetic acid (C2H4O2) and disodium hydrogen phosphate dehydrate (Na2HPO4.2H2O) in combination with sodium alginate in order to improve theirs moldable characteristic. The concentrations of the aqueous solutions and sodium alginate were varied to investigate the effects of different aqueous solution and alginate on properties of the cements. The cement paste was prepared by mixing cement powder (P) with aqueous solution (L) in a P/L ratio of 1.0 g/ 0.35 ml. X-ray diffraction (XRD) was used to analyses phase formation of the cements. Setting times and compressive strength of the set CPCs were measured using the Gilmore apparatus and Universal testing machine, respectively. The results showed that CPCs could be produced by using both basic (Na2HPO4.2H2O) and acidic (C2H4O2) solutions. XRD results show the precipitation of hydroxyapatite in all cement samples. No change in phase formation among cements using difference concentrations of Na2HPO4.2H2O solutions. With increasing concentration of acidic solutions, samples obtained less hydroxyapatite with a high dicalcium phosphate dehydrate leaded to a shorter setting time. Samples with sodium alginate exhibited higher crystallization of hydroxyapatite than that of without alginate as a result of shorten setting time in basic solution but a longer setting time in acidic solution. The stronger cement was attained from samples using acidic solution with sodium alginate; however it was lower than using the basic solution. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=calcium%20phosphate%20cements" title="calcium phosphate cements">calcium phosphate cements</a>, <a href="https://publications.waset.org/abstracts/search?q=TTCP" title=" TTCP"> TTCP</a>, <a href="https://publications.waset.org/abstracts/search?q=DCPA" title=" DCPA"> DCPA</a>, <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite" title=" hydroxyapatite"> hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=properties" title=" properties"> properties</a> </p> <a href="https://publications.waset.org/abstracts/17449/preparation-and-characterization-of-calcium-phosphate-cement" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/17449.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">390</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9205</span> Characterization of Crustin from Litopenaeus vannamei</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Suchao%20Donpudsa">Suchao Donpudsa</a>, <a href="https://publications.waset.org/abstracts/search?q=Anchalee%20Tassanakajon"> Anchalee Tassanakajon</a>, <a href="https://publications.waset.org/abstracts/search?q=Vichien%20Rimphanitchayakit"> Vichien Rimphanitchayakit</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A crustin gene, LV-SWD1, previously found in the hemocyte cDNA library of Litopenaeus vannamei, contains the open reading frames of 288 bp encoding a putative protein of 96 amino acid residues. The putative signal peptides of the LV-SWD1 were identified using the online SignalP 3.0 with predicted cleavage sites between Ala24-Val25, resulting in 72 residue mature protein with calculated molecular mass of 7.4 kDa and predicted pI of 8.5. This crustin contains a Arg-Pro rich region at the amino-terminus and a single whey acidic protein (WAP) domain at the carboxyl-terminus. In order to characterize their properties and biological activities, the recombinant crustin protein was produced in the Escherichia coli expression system. Antimicrobial assays showed that the growth of Bacillus subtilis was inhibited by this recombinant crustin with MIC of about 25-50 µM. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=crustin" title="crustin">crustin</a>, <a href="https://publications.waset.org/abstracts/search?q=single%20whey%20acidic%20protein" title=" single whey acidic protein"> single whey acidic protein</a>, <a href="https://publications.waset.org/abstracts/search?q=Litopenaeus%20vannamei" title=" Litopenaeus vannamei"> Litopenaeus vannamei</a>, <a href="https://publications.waset.org/abstracts/search?q=antimicrobial%20activity" title=" antimicrobial activity"> antimicrobial activity</a> </p> <a href="https://publications.waset.org/abstracts/40824/characterization-of-crustin-from-litopenaeus-vannamei" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/40824.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">244</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9204</span> Enzymatic Esterification of Sardine Oil Processed in Morocco</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20Kharroubi">M. Kharroubi</a>, <a href="https://publications.waset.org/abstracts/search?q=Y.%20Rady"> Y. Rady</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20Bellali"> F. Bellali</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Himmi"> S. Himmi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The global objective of this study is to upgrade the sardine oil processed in Morocco by using enzymatic solutions. The specific objective of this part of study is to optimize the various parameters involved in enzymatic deacidification of fish oil processed in Morocco: pressure, ratio of oil/novozymes 435, ratio of oil/glycerol, temperature. The best deacidification yields were obtained with: -A temperature of 70 °C; -A ratio -Oil/Glycerol: 2% (% P); -A ratio -Oil/Novozyme 435: 1% (% P); -A pressure: 15 to 25 mbar. On the other hand, the study of the effect of initial oil acidity showed that whatever the acidity of the oil studied (very acidic, or low acidic), the final yields are high. Acidity does not reduce the reaction efficiency. From an industrial point of view, this represents a competitive advantage to consider. This eco-friend enzymatic solution may allows Moroccan fish oil producers to achieve acid number values that meet the standard. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=sardine%20oil" title="sardine oil">sardine oil</a>, <a href="https://publications.waset.org/abstracts/search?q=enzymatic%20esterfication" title=" enzymatic esterfication"> enzymatic esterfication</a>, <a href="https://publications.waset.org/abstracts/search?q=desacidification" title=" desacidification"> desacidification</a>, <a href="https://publications.waset.org/abstracts/search?q=acid%20number" title=" acid number"> acid number</a> </p> <a href="https://publications.waset.org/abstracts/17956/enzymatic-esterification-of-sardine-oil-processed-in-morocco" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/17956.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">385</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9203</span> Mineralized Nanoparticles as a Contrast Agent for Ultrasound and Magnetic Resonance Imaging</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jae%20Won%20Lee">Jae Won Lee</a>, <a href="https://publications.waset.org/abstracts/search?q=Kyung%20Hyun%20Min"> Kyung Hyun Min</a>, <a href="https://publications.waset.org/abstracts/search?q=Hong%20Jae%20Lee"> Hong Jae Lee</a>, <a href="https://publications.waset.org/abstracts/search?q=Sang%20Cheon%20Lee"> Sang Cheon Lee</a> </p> <p class="card-text"><strong>Abstract:</strong></p> To date, imaging techniques have attracted much attention in medicine because the detection of diseases at an early stage provides greater opportunities for successful treatment. Consequently, over the past few decades, diverse imaging modalities including magnetic resonance (MR), positron emission tomography, computed tomography, and ultrasound (US) have been developed and applied widely in the field of clinical diagnosis. However, each of the above-mentioned imaging modalities possesses unique strengths and intrinsic weaknesses, which limit their abilities to provide accurate information. Therefore, multimodal imaging systems may be a solution that can provide improved diagnostic performance. Among the current medical imaging modalities, US is a widely available real-time imaging modality. It has many advantages including safety, low cost and easy access for patients. However, its low spatial resolution precludes accurate discrimination of diseased region such as cancer sites. In contrast, MR has no tissue-penetrating limit and can provide images possessing exquisite soft tissue contrast and high spatial resolution. However, it cannot offer real-time images and needs a comparatively long imaging time. The characteristics of these imaging modalities may be considered complementary, and the modalities have been frequently combined for the clinical diagnostic process. Biominerals such as calcium carbonate (CaCO3) and calcium phosphate (CaP) exhibit pH-dependent dissolution behavior. They demonstrate pH-controlled drug release due to the dissolution of minerals in acidic pH conditions. In particular, the application of this mineralization technique to a US contrast agent has been reported recently. The CaCO3 mineral reacts with acids and decomposes to generate calcium dioxide (CO2) gas in an acidic environment. These gas-generating mineralized nanoparticles generated CO2 bubbles in the acidic environment of the tumor, thereby allowing for strong echogenic US imaging of tumor tissues. On the basis of this previous work, it was hypothesized that the loading of MR contrast agents into the CaCO3 mineralized nanoparticles may be a novel strategy in designing a contrast agent for dual imaging. Herein, CaCO3 mineralized nanoparticles that were capable of generating CO2 bubbles to trigger the release of entrapped MR contrast agents in response to tumoral acidic pH were developed for the purposes of US and MR dual-modality imaging of tumors. Gd2O3 nanoparticles were selected as an MR contrast agent. A key strategy employed in this study was to prepare Gd2O3 nanoparticle-loaded mineralized nanoparticles (Gd2O3-MNPs) using block copolymer-templated CaCO3 mineralization in the presence of calcium cations (Ca2+), carbonate anions (CO32-) and positively charged Gd2O3 nanoparticles. The CaCO3 core was considered suitable because it may effectively shield Gd2O3 nanoparticles from water molecules in the blood (pH 7.4) before decomposing to generate CO2 gas, triggering the release of Gd2O3 nanoparticles in tumor tissues (pH 6.4~7.4). The kinetics of CaCO3 dissolution and CO2 generation from the Gd2O3-MNPs were examined as a function of pH and pH-dependent in vitro magnetic relaxation; additionally, the echogenic properties were estimated to demonstrate the potential of the particles for the tumor-specific US and MR imaging. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=calcium%20carbonate" title="calcium carbonate">calcium carbonate</a>, <a href="https://publications.waset.org/abstracts/search?q=mineralization" title=" mineralization"> mineralization</a>, <a href="https://publications.waset.org/abstracts/search?q=ultrasound%20imaging" title=" ultrasound imaging"> ultrasound imaging</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20resonance%20imaging" title=" magnetic resonance imaging"> magnetic resonance imaging</a> </p> <a href="https://publications.waset.org/abstracts/45843/mineralized-nanoparticles-as-a-contrast-agent-for-ultrasound-and-magnetic-resonance-imaging" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/45843.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">236</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9202</span> Geopolymer Concrete: A Review of Properties, Applications and Limitations</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Abbas%20Ahmed%20Albu%20Shaqraa">Abbas Ahmed Albu Shaqraa</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The concept of a safe environment and low greenhouse gas emissions is a common concern especially in the construction industry. The produced carbon dioxide (CO2) emissions are nearly a ton in producing only one ton of Portland cement, which is the primary ingredient of concrete. Current studies had investigated the utilization of several waste materials in producing a cement free concrete. The geopolymer concrete is a green material that results from the reaction of aluminosilicate material with an alkaline liquid. A summary of several recent researches in geopolymer concrete will be presented in this manuscript. In addition, the offered presented review considers the use of several waste materials including fly ash, granulated blast furnace slag, cement kiln dust, kaolin, metakaolin, and limestone powder as binding materials in making geopolymer concrete. Moreover, the mechanical, chemical and thermal properties of geopolymer concrete will be reviewed. In addition, the geopolymer concrete applications and limitations will be discussed as well. The results showed a high early compressive strength gain in geopolymer concrete when dry- heating or steam curing was performed. Also, it was stated that the outstanding acidic resistance of the geopolymer concrete made it possible to be used where the ordinary Portland cement concrete was doubtable. Thus, the commercial geopolymer concrete pipes were favored for sewer system in case of high acidic conditions. Furthermore, it was reported that the geopolymer concrete could stand up to 1200 °C in fire without losing its strength integrity whereas the Portland cement concrete was losing its function upon heating to some 100s °C only. However, the geopolymer concrete still considered as an emerging field and occupied mainly by the precast industries. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=geopolymer%20concrete" title="geopolymer concrete">geopolymer concrete</a>, <a href="https://publications.waset.org/abstracts/search?q=Portland%20cement%20concrete" title=" Portland cement concrete"> Portland cement concrete</a>, <a href="https://publications.waset.org/abstracts/search?q=alkaline%20liquid" title=" alkaline liquid"> alkaline liquid</a>, <a href="https://publications.waset.org/abstracts/search?q=compressive%20strength" title=" compressive strength"> compressive strength</a> </p> <a href="https://publications.waset.org/abstracts/44283/geopolymer-concrete-a-review-of-properties-applications-and-limitations" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/44283.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">221</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9201</span> Effect of Temperature on the Structural and Optical Properties of ZnS Thin Films Obtained by Chemical Bath Deposition in Acidic Medium</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hamid%20Merzouk">Hamid Merzouk</a>, <a href="https://publications.waset.org/abstracts/search?q=Dajhida%20Talantikite"> Dajhida Talantikite</a>, <a href="https://publications.waset.org/abstracts/search?q=Amel%20Tounsi"> Amel Tounsi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Thin films of ZnS have been deposited by chemical route into acidic medium. The deposition time fixed at 5 hours, and the bath temperature varied from 80° C to 95°C with an interval of 5°C. The X-ray diffraction (XRD), UV/ visible spectrophotometry, Fourier Transform Infrared spectroscopy (FTIR) have been used to study the effect of temperature on the structural and optical properties of ZnS thin films. The XRD spectrum of the ZnS layer obtained shows an increase of peaks intensity of ZnS with increasing bath temperature. The study of optical properties exhibit good transmittance (60–80% in the visible region), and the band gap energy of the ZnS thin film decrease from 3.71 eV to 3.64 eV while the refractive index (n) increase with increasing temperature bath. The FTIR analyze confirm our studies and show characteristics bands of vibration of Zn-S. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ZnS%20thin%20films" title="ZnS thin films">ZnS thin films</a>, <a href="https://publications.waset.org/abstracts/search?q=XRD%20spectra" title=" XRD spectra"> XRD spectra</a>, <a href="https://publications.waset.org/abstracts/search?q=optical%20gap" title=" optical gap"> optical gap</a>, <a href="https://publications.waset.org/abstracts/search?q=XRD" title=" XRD"> XRD</a> </p> <a href="https://publications.waset.org/abstracts/143498/effect-of-temperature-on-the-structural-and-optical-properties-of-zns-thin-films-obtained-by-chemical-bath-deposition-in-acidic-medium" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/143498.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">155</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9200</span> The Effects of pH on p53 Phosphorylation by Ataxia Telangiectasia Mutated Kinase</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Serap%20Pektas">Serap Pektas</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Ataxia telangiectasia mutated (ATM) is a serine-threonine kinase, which is the major regulator of the DNA damage response. ATM is activated upon the formation of DNA double-strand breaks (DSBs) in the cells. ATM phosphorylates the proteins involved in apoptotic responses, cell cycle checkpoint control, DNA repair, etc. Tumor protein p53, known as p53 is one of these proteins that phosphorylated by ATM. Phosphorylation of p53 at Ser15 residue leads to p53 stabilization in the cells. Often enzymes activity is affected by hydrogen ion concentration (pH). In order to find the optimal pH range for ATM activity, steady-state kinetic assays were performed at acidic and basic pH ranges. Ser15 phosphorylation of p53 is determined by using ELISA. The results indicated that the phosphorylation rate was better at basic pH range compared with the acidic pH range. This could be due to enzyme stability, or enzyme-substrate interaction is pH dependent. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ataxia%20telangiectasia%20mutated" title="ataxia telangiectasia mutated">ataxia telangiectasia mutated</a>, <a href="https://publications.waset.org/abstracts/search?q=DNA%20double%20strand%20breaks" title=" DNA double strand breaks"> DNA double strand breaks</a>, <a href="https://publications.waset.org/abstracts/search?q=DNA%20repair" title=" DNA repair"> DNA repair</a>, <a href="https://publications.waset.org/abstracts/search?q=tumor%20protein%20p53" title=" tumor protein p53"> tumor protein p53</a> </p> <a href="https://publications.waset.org/abstracts/109929/the-effects-of-ph-on-p53-phosphorylation-by-ataxia-telangiectasia-mutated-kinase" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/109929.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">134</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9199</span> Nanoparticle Based Green Inhibitor for Corrosion Protection of Zinc in Acidic Medium</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Neha%20Parekh">Neha Parekh</a>, <a href="https://publications.waset.org/abstracts/search?q=Divya%20Ladha"> Divya Ladha</a>, <a href="https://publications.waset.org/abstracts/search?q=Poonam%20Wadhwani"> Poonam Wadhwani</a>, <a href="https://publications.waset.org/abstracts/search?q=Nisha%20Shah"> Nisha Shah </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Nano scaled materials have attracted tremendous interest as corrosion inhibitor due to their high surface area on the metal surfaces. It is well known that the zinc oxide nanoparticles have higher reactivity towards aqueous acidic solution. This work presents a new method to incorporate zinc oxide nanoparticles with white sesame seeds extract (nano-green inhibitor) for corrosion protection of zinc in acidic medium. The morphology of the zinc oxide nanoparticles was investigated by TEM and DLS. The corrosion inhibition efficiency of the green inhibitor and nano-green inhibitor was determined by Gravimetric and electrochemical impedance spectroscopy (EIS) methods. Gravimetric measurements suggested that nano-green inhibitor is more effective than green inhibitor. Furthermore, with the increasing temperature, inhibition efficiency increases for both the inhibitors. In addition, it was established the Temkin adsorption isotherm fits well with the experimental data for both the inhibitors. The effect of temperature and Temkin adsorption isotherm revealed Chemisorption mechanism occurring in the system. The activation energy (Ea) and other thermodynamic parameters for inhibition process were calculated. The data of EIS showed that the charge transfer controls the corrosion process. The surface morphology of zinc metal (specimen) in absence and presence of green inhibitor and nano-green inhibitor were performed using Scanning Electron Microscopy (SEM) and Atomic Force Microscopy (AFM) techniques. The outcomes indicated a formation of a protective layer over zinc metal (specimen). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=corrosion" title="corrosion">corrosion</a>, <a href="https://publications.waset.org/abstracts/search?q=green%20inhibitor" title=" green inhibitor"> green inhibitor</a>, <a href="https://publications.waset.org/abstracts/search?q=nanoparticles" title=" nanoparticles"> nanoparticles</a>, <a href="https://publications.waset.org/abstracts/search?q=zinc" title=" zinc "> zinc </a> </p> <a href="https://publications.waset.org/abstracts/40529/nanoparticle-based-green-inhibitor-for-corrosion-protection-of-zinc-in-acidic-medium" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/40529.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">454</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9198</span> Acid Mine Drainage Remediation Using Silane and Phosphate Coatings</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20Chiliza">M. Chiliza</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20P.%20Mbukwane"> H. P. Mbukwane</a>, <a href="https://publications.waset.org/abstracts/search?q=P%20Masita"> P Masita</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20Rutto"> H. Rutto</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Acid mine drainage (AMD) one of the main pollutants of water in many countries that have mining activities. AMD results from the oxidation of pyrite and other metal sulfides. When these metals gets exposed to moisture and oxygen, leaching takes place releasing sulphate and Iron. Acid drainage is often noted by 'yellow boy,' an orange-yellow substance that occurs when the pH of acidic mine-influenced water raises above pH 3, so that the previously dissolved iron precipitates out. The possibility of using environmentally friendly silane and phosphate based coatings on pyrite to remediate acid mine drainage and prevention at source was investigated. The results showed that both coatings reduced chemical oxidation of pyrite based on Fe and sulphate release. Furthermore, it was found that silane based coating performs better when coating synthesis take place in a basic hydrolysis than in an acidic state. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=acid%20mine%20drainage" title="acid mine drainage">acid mine drainage</a>, <a href="https://publications.waset.org/abstracts/search?q=pyrite" title=" pyrite"> pyrite</a>, <a href="https://publications.waset.org/abstracts/search?q=silane" title=" silane"> silane</a>, <a href="https://publications.waset.org/abstracts/search?q=phosphate" title=" phosphate"> phosphate</a> </p> <a href="https://publications.waset.org/abstracts/59866/acid-mine-drainage-remediation-using-silane-and-phosphate-coatings" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/59866.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">342</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9197</span> Development of an Erodable Matrix Drug Delivery Platform for Controled Delivery of Non Steroidal Anti Inflamatory Drugs Using Melt Granulation Process</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=A.%20Hilsana">A. Hilsana</a>, <a href="https://publications.waset.org/abstracts/search?q=Vinay%20U.%20Rao"> Vinay U. Rao</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Sudhakar"> M. Sudhakar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Even though a number of non-steroidal anti-inflammatory drugs (NSAIDS) are available with different chemistries, they share a common solubility characteristic that is they are relatively more soluble in alkaline environment and practically insoluble in acidic environment. This work deals with developing a wax matrix drug delivery platform for controlled delivery of three model NSAIDS, Diclofenac sodium (DNa), Mefenamic acid (MA) and Naproxen (NPX) using the melt granulation technique. The aim of developing the platform was to have a general understanding on how an erodible matrix system modulates drug delivery rate and extent and how it can be optimized to give a delivery system which shall release the drug as per a common target product profile (TPP). Commonly used waxes like Cetostearyl alcohol and stearic acid were used singly an in combination to achieve a TPP of not 15 to 35% in 1 hour and not less than 80% Q in 24 hours. Full factorial design of experiments was followed for optimization of the formulation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=NSAIDs" title="NSAIDs">NSAIDs</a>, <a href="https://publications.waset.org/abstracts/search?q=controlled%20delivery" title=" controlled delivery"> controlled delivery</a>, <a href="https://publications.waset.org/abstracts/search?q=target%20product%20profile" title=" target product profile"> target product profile</a>, <a href="https://publications.waset.org/abstracts/search?q=melt%20granulation" title=" melt granulation"> melt granulation</a> </p> <a href="https://publications.waset.org/abstracts/9021/development-of-an-erodable-matrix-drug-delivery-platform-for-controled-delivery-of-non-steroidal-anti-inflamatory-drugs-using-melt-granulation-process" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/9021.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">334</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9196</span> Catalytic Effect on Eco Friendly Functional Material in Flame Retardancy of Cellulose</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Md.%20Abdul%20Hannan">Md. Abdul Hannan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Two organophosphorus compounds, namely diethyloxymethyl-9-oxa-10- phosphaphenanthrene-10-oxide (DOPAC) and diethyl (2,2-diethoxyethyl) phosphonate (DPAC) were applied on cotton cellulose to impart non-carcinogenic and durable (in alkaline washing) flame retardant property to it. Some acidic catalysts, sodium dihydrogen phosphate (NaH2PO4), ammonium dihydrogen phosphate (NH4H2PO4) and phosphoric acid (H3PO4) were successfully used. Synergistic acidic catalyzing effect of NaH2PO4+H3PO4 and NaH2PO4+NH4H2PO4 was also investigated. Appreciable limiting oxygen index (LOI) value of 23.2% was achieved in case of the samples treated with flame retardant (FR) compound DPAC along with the combined acidic catalyzing effect. A distinguishing outcome of total heat of combustion (THC) 3.27 KJ/g was revealed during pyrolysis combustion flow calorimetry (PCFC) test of the treated sample. In respect of thermal degradation, low temperature dehydration in conjugation with sufficient amount of char residue (30.5%) was obtained in case of DPAC treated sample. Consistently, the temperature of peak heat release rate (TPHRR) (325°C) of DPAC treated sample supported the expected low temperature pyrolysis in condensed phase mechanism. Subsequent thermogravimetric analysis (TGA) also reported inspiring weight retention% of the treated samples. Furthermore, for both of the flame retardant compounds, effect of different catalysts, considering both individual and combined, effect of solvents and overall the optimization of the process parameters were studied in detail. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cotton%20cellulose" title="cotton cellulose">cotton cellulose</a>, <a href="https://publications.waset.org/abstracts/search?q=organophosphorus%20flame%20retardant" title=" organophosphorus flame retardant"> organophosphorus flame retardant</a>, <a href="https://publications.waset.org/abstracts/search?q=acetal%20linkage" title=" acetal linkage"> acetal linkage</a>, <a href="https://publications.waset.org/abstracts/search?q=THC" title=" THC"> THC</a>, <a href="https://publications.waset.org/abstracts/search?q=HRR" title=" HRR"> HRR</a>, <a href="https://publications.waset.org/abstracts/search?q=PHHR" title=" PHHR"> PHHR</a>, <a href="https://publications.waset.org/abstracts/search?q=char%20residue" title=" char residue"> char residue</a>, <a href="https://publications.waset.org/abstracts/search?q=LOI" title=" LOI"> LOI</a> </p> <a href="https://publications.waset.org/abstracts/3013/catalytic-effect-on-eco-friendly-functional-material-in-flame-retardancy-of-cellulose" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/3013.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">266</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9195</span> Study of the Efficiency of a Synthetic Wax for Corrosion Protection of Steel in Aggressive Environments</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Laidi%20Babouri">Laidi Babouri</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The remarkable properties of steel, such as hardness and impact resistance, motivate their use in the automotive manufacturing industry. However, due to the very vulnerable environmental conditions of use, the steel that makes up the car body can corrode. This situation is motivating more and more automobile manufacturers to develop research to develop processes minimizing the rate of degradation of the physicomechanical properties of these materials. The present work falls within this perspective; it presents the results of a research study focused on the use of synthetic wax for the protection of steel, type XES (DC04), against corrosion in aggressive environments. The media used in this study are an acid medium with a pH=5.6, a 3% chloride medium, and a dry medium. Evaluation of the protective power of synthetic wax in different environments was carried out using mass loss techniques (immersion), completed by electrochemical techniques (stationary and transient). The results of the immersion of the steel samples, with a surface area of (1.44 cm²), in the various media, for a period of 30 days, using the immersion technique, showed high protective efficiency of synthetic wax in acidic and saline environments, with a lesser degree in a dry environment. Moreover, the study of the protective power, using electrochemical techniques, confirmed the results obtained in static mode (loss of mass), the protective efficiency of synthetic wax, against the corrosion of steel, in different environments, which reaches a maximum rate of 99.87% in a saline environment. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=corrosion" title="corrosion">corrosion</a>, <a href="https://publications.waset.org/abstracts/search?q=steel" title=" steel"> steel</a>, <a href="https://publications.waset.org/abstracts/search?q=industrial%20wax" title=" industrial wax"> industrial wax</a>, <a href="https://publications.waset.org/abstracts/search?q=environment" title=" environment"> environment</a>, <a href="https://publications.waset.org/abstracts/search?q=mass%20loss" title=" mass loss"> mass loss</a>, <a href="https://publications.waset.org/abstracts/search?q=electrochemical%20techniques" title=" electrochemical techniques"> electrochemical techniques</a> </p> <a href="https://publications.waset.org/abstracts/165660/study-of-the-efficiency-of-a-synthetic-wax-for-corrosion-protection-of-steel-in-aggressive-environments" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/165660.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">75</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9194</span> Canned Sealless Pumps for Hazardous Applications</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shuja%20Alharbi">Shuja Alharbi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Oil and Gas industry has many applications considered as toxic or hazardous, where process fluid leakage is not permitted and leads to health, safety, and environmental impacts. Caustic/Acidic applications, High Benzene Concentrations, Hydrogen sulfide rich oil/gas as well as liquids operating above their auto-ignition temperatures are examples of such liquids that pose as a risk to the industry operation, and for those, special arrangements are in place to allow for the safe operation environment. Pumps in the industry requires special attention, specifically in the interface between the fluid and the environment, where the potential of leakages are foreseen. Mechanical Seals are used to contain the fluid within the equipment, but the prices are ever increasing for such seals, along with maintenance, design, and operating requirements. Several alternatives to seals are being employed nowadays, such as Sealless systems, which is hermitically sealed from the atmosphere and does not require sealing. This technology is considered relatively new and requires more studies to understand the limitations and factors associated from an owner and design perspective. Things like financial factors, maintenance factors, and design limitation should be studies further in order to have a mature and reliable technical solution available to end users. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=pump" title="pump">pump</a>, <a href="https://publications.waset.org/abstracts/search?q=sealless" title=" sealless"> sealless</a>, <a href="https://publications.waset.org/abstracts/search?q=selection" title=" selection"> selection</a>, <a href="https://publications.waset.org/abstracts/search?q=failure" title=" failure"> failure</a> </p> <a href="https://publications.waset.org/abstracts/155431/canned-sealless-pumps-for-hazardous-applications" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/155431.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">100</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9193</span> Forced Degradation Study of Rifaximin Formulated Tablets to Determine Stability Indicating Nature of High-Performance Liquid Chromatography Analytical Method </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Abid%20Fida%20Masih">Abid Fida Masih</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Forced degradation study of Rifaximin was conducted to determine the stability indicating potential of HPLC testing method for detection of Rifaximin in formulated tablets to be employed for quality control and stability testing. The questioned method applied with mobile phase methanol: water (70:30), 5µm, 250 x 4.6mm, C18 column, wavelength 293nm and flow rate of 1.0 ml/min. Forced degradation study was performed under oxidative, acidic, basic, thermal and photolytic conditions. The applied method successfully determined the degradation products after acidic and basic degradation without interfering with Rifaximin detection. Therefore, the method was said to be stability indicating and can be applied for quality control and stability testing of Rifaxmin tablets during its shelf life. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=forced%20degradation" title="forced degradation">forced degradation</a>, <a href="https://publications.waset.org/abstracts/search?q=high-performance%20liquid%20chromatography" title=" high-performance liquid chromatography"> high-performance liquid chromatography</a>, <a href="https://publications.waset.org/abstracts/search?q=method%20validation" title=" method validation"> method validation</a>, <a href="https://publications.waset.org/abstracts/search?q=rifaximin" title=" rifaximin"> rifaximin</a>, <a href="https://publications.waset.org/abstracts/search?q=stability%20indicating%20method" title=" stability indicating method"> stability indicating method</a> </p> <a href="https://publications.waset.org/abstracts/76445/forced-degradation-study-of-rifaximin-formulated-tablets-to-determine-stability-indicating-nature-of-high-performance-liquid-chromatography-analytical-method" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/76445.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">313</span> </span> </div> </div> <ul class="pagination"> <li class="page-item disabled"><span class="page-link">‹</span></li> <li class="page-item active"><span class="page-link">1</span></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=acidic%20environment&page=2">2</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=acidic%20environment&page=3">3</a></li> <li class="page-item"><a class="page-link" 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