Cell Sorters and Single Cell Dispensers

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class="field_block:paragraph:h1_2_2_text_to_media:field_indv_h1"> <div><h1>Cell Sorter and Single Cell Dispensers</h1></div> </div> <div class="field_block:paragraph:h1_2_2_text_to_media:field_lg_sngl_frmtd_text_global"> <div><p>The Fastest Way to Single Cell Isolation</p></div> </div> <div class="field_block:paragraph:h1_2_2_text_to_media:field_call_to_action_global"> <a href="/p/instruments/cell-sorting-single-cell-dispensing/request-quote" class="btn btn-primary" type="link"> Request Pricing </a> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:h1_2_2_text_to_media:field_indv_media"> <div> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/obt-healthy-cell-hero-480x480-v1.png" alt="healthy cell" fetchpriority="high" > </div> </div> </div> </div> </div> </div> </div> </div> </div> </section> </div> </div> </header> </div> <div id="main" class="container-fluid 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class="field_block:paragraph:2_2_text_to_media:field_header_2_global"> <div><h2>Single Cell Isolation</h2></div> </div> <div class="field_block:paragraph:2_2_text_to_media:field_lg_sngl_frmtd_text_global"> <div><p><a name="pala"></a>The Pala Cell Sorter and Single Cell Dispenser is a platform that:</p><ul><li><strong>Boosts efficiency in the lab </strong>by isolating and dispensing cells in ≤ 7 minutes</li><li><strong>Gives you high-quality, viable cells </strong>through gentle sorting (<2 psi)</li><li><strong>Adapts to a wide range of cell densities</strong>, from as little as 100 cell/mL</li><li><strong>Ensures consistency and ease </strong>through full automation</li><li><strong>Fits into your budget and cell culture hood </strong>by being affordable, light-weight, and compact</li></ul></div> </div> <div class="field_block:paragraph:2_2_text_to_media:field_call_to_action_global"> <a href="/p/instruments/cell-sorting-single-cell-dispensing/request-quote" class="btn btn-primary" type="link"> Request More Information </a> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_text_to_media:field_indv_media"> <div> <img src="https://resources.bio-techne.com/bio-techne-assets/images/products/pala-dimensions-525x300.png" alt="Pala Cell Sorter image" loading="lazy" > </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--clickable-icons-container paragraph--view-mode--default"> <div class="container"> <div class="row"> <div class="col p-0 text-center"> <h2>Explore Cell Sorting and Single Cell Dispensers</h2> </div> </div> <div class="row"> <div class="col text-center"> </div> </div> <div class="row"> <div class="row justify-content-center"> <div class="col-xl-2 col-lg-2 col-md-4 col-sm-6 col-6 mb-4"> <div class="paragraph paragraph--type--indvidual-clickable-icon paragraph--view-mode--default card p-3 text-center h-100 mb-0"> <a href="#performance" > <div><article> <div><img src='https://resources.bio-techne.com/bio-techne-assets/images/icons/poster-icon-light-blue.png' alt='Scientific Poster icon'></div> </article> </div> <p><strong>Performance</strong></p> </a> </div> </div> <div class="col-xl-2 col-lg-2 col-md-4 col-sm-6 col-6 mb-4"> <div class="paragraph paragraph--type--indvidual-clickable-icon paragraph--view-mode--default card p-3 text-center h-100 mb-0"> <a href="#applications" > <div><article> <div><img src='https://resources.bio-techne.com/bio-techne-assets/images/about/CSR-update_icon-1.png' alt='CSR Icon 1'></div> </article> </div> <p><strong>Applications</strong></p> </a> </div> </div> <div class="col-xl-2 col-lg-2 col-md-4 col-sm-6 col-6 mb-4"> <div class="paragraph paragraph--type--indvidual-clickable-icon paragraph--view-mode--default card p-3 text-center h-100 mb-0"> <a href="#models" > <div><article> <div><img src='https://resources.bio-techne.com/bio-techne-assets/images/icons/namocell-light-blue-icon.png' alt='Namocell Icon'></div> </article> </div> <p><strong>Models</strong></p> </a> </div> </div> <div class="col-xl-2 col-lg-2 col-md-4 col-sm-6 col-6 mb-4"> <div class="paragraph paragraph--type--indvidual-clickable-icon paragraph--view-mode--default card p-3 text-center h-100 mb-0"> <a href="#resources" > <div><article> <div><img src='https://resources.bio-techne.com/bio-techne-assets/images/about/ISSCR-graphics_resource.png' alt='Literature Icon'></div> </article> </div> <p><strong>Resources</strong></p> </a> </div> </div> <div class="col-xl-2 col-lg-2 col-md-4 col-sm-6 col-6 mb-4"> <div class="paragraph paragraph--type--indvidual-clickable-icon paragraph--view-mode--default card p-3 text-center h-100 mb-0"> <a href="/resources/instrument-citations?instrument-platform=cell%20sorting%20and%20single%20cell%20dispensing" > <div><article> <div><img src='https://resources.bio-techne.com/bio-techne-assets/images/icons/task-check-list_Light_Blue.png' alt='Checklist icon'></div> </article> </div> <p><strong>Citations</strong></p> </a> </div> </div> <div class="col-xl-2 col-lg-2 col-md-4 col-sm-6 col-6 mb-4"> <div class="paragraph paragraph--type--indvidual-clickable-icon paragraph--view-mode--default card p-3 text-center h-100 mb-0"> <a href="https://resources.bio-techne.com/bio-techne-assets/docs/literature/bio-techne-cell-sorter-and-single-cell-dispenser-product-brochure.pdf" > <div><article> <div><img src='https://resources.bio-techne.com/bio-techne-assets/images/about/ISSCR-graphics_resource.png' alt='Literature Icon'></div> </article> </div> <p><strong>Brochure</strong></p> </a> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--header"> <div> <div><h2>Why Pala and Hana for your Single Cell Isolation needs?</h2></div> </div> </div> </div> <div> <div class="paragraph paragraph--type--_-2-media-to-text mb-4 paragraph--view-mode--default"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--50-50"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_indv_media"> <div> <article> <div class="youtube-video-place"> <lite-youtube videoid="xU0MAfe4clg" params="rel=0" style="background-image: url('https://img.youtube.com/vi/xU0MAfe4clg/maxresdefault.jpg');"> <a href="https://www.youtube.com/embed/xU0MAfe4clg?autoplay=1" class="lty-playbtn" title="Bio-Techne's Cell Sorting and Single Cell Dispensing Instruments"> <span class="lyt-visually-hidden">Bio-Techne's Cell Sorting and Single Cell Dispensing Instruments</span> </a> </lite-youtube> </div> </article> </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_header_2_global"> <div><h3>Sort Cells According to Your Requirements</h3></div> </div> <div class="field_block:paragraph:2_2_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p>Leverage the powerful combination of microfluidics, flow cytometry, and liquid dispensing in the Pala and Hana systems to:</p><ul><li><strong>Liquid Dispensing:</strong> Get single cells dispensed into 96- or 384-well plates in minutes</li><li><strong>Microfluidics in a Cartridge:</strong> Enables sterile single cell sorting</li><li><strong>Flow Cytometry:</strong> Gently sorting for maximum cell viability, no prior experience with flow cytometry needed</li></ul></div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--full-page-text-with-media mb-4 paragraph--view-mode--default"> <div><h2>Accelerate Your Workflow</h2></div> <div> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/single-cell-dispenser-workflow-1470x400-v3.png" alt="Pala Single Cell Sorting and Single Cell Dispensing instrument workflow vs. traditional FACS workflow" loading="lazy" > </div> <div><p><sup>*</sup>Chakrabarti, Lina, <em>et al.</em> “Simplifying Stable CHO Cell Line Generation with High Probability of Monoclonality by Using Microfluidic Dispensing as an Alternative to Fluorescence Activated Cell Sorting.” Biotechnology Progress, 10 Mar. 2024, <a href="https://doi.org/10.1002/btpr.3441" target="_blank">https://doi.org/10.1002/btpr.3441</a>. Accessed 11 Apr. 2024.</p></div> </div> </div> <div> <div class="paragraph paragraph--type--freeform mb-4 paragraph--view-mode--default"> <div><p><a name="performance"></a></p><h2>Performance</h2></div> </div> </div> <div> <div class="paragraph paragraph--type--_-2-media-to-text mb-4 paragraph--view-mode--default"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--50-50"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_indv_media"> <div> <a href="https://www.bio-techne.com/resources/literature/enrichment-of-high-titer-cho-cells-with-single-cell-dispenser" title="View Full Application Note" > <img src="https://resources.bio-techne.com/bio-techne-assets/images/applications/cell-line-development-cho-cloning-efficiency-fig-3.jpg" alt="Graph highlighting improved efficiency of CHO cell cloning efficiency with Bio-Techne's single cell sorters versus FACS and limited dilution" loading="lazy" > </a> </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p>Comparison of Pala Single Cell Dispenser with traditional methods of sorting cells for clonal outgrowth. Pala Single Cell Dispenser, was used alongside limiting dilution (LDC) and FACS sorting to sort CHO host cells for a single cell cloning protocol sorting. Results highlight the higher cloning efficiencies obtained with Pala compared with LDC and FACS.</p></div> </div> <div class="field_block:paragraph:2_2_media_to_text:field_call_to_action_global"> <a href="/resources/literature/enrichment-of-high-titer-cho-cells-with-single-cell-dispenser" class="btn btn-primary" type="link"> View Full Application Note </a> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--_-2-media-to-text mb-4 paragraph--view-mode--default"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--50-50"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_indv_media"> <div> <a href="https://www.bio-techne.com/resources/literature/single-cell-deposition-efficiency" title="View Full Application Note" > <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/reported-deposition-efficiencies-graph.png" alt="Reported Deposition Efficiencies" loading="lazy" > </a> </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p>Reliable deposition of single cells into tissue culture plates (one cell per well) is an essential consideration for clonal cell isolation and expansion. Pala and Hana Cell Sorter and Single Cell Dispensers provide a fast and reliable alternative for single cell isolation, alleviating the need for manual pipetting while preserving cell integrity by sorting at a gentle pressure of <2 psi.</p><p>Deposition rates were calculated for single cells, doublets, and empty wells after visual inspection scoring of seven plates in each condition.</p></div> </div> <div class="field_block:paragraph:2_2_media_to_text:field_call_to_action_global"> <a href="/resources/literature/single-cell-deposition-efficiency" class="btn btn-primary" type="link"> View Full Application Note </a> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--freeform mb-4 paragraph--view-mode--default"> <div><p><a name="applications"></a></p></div> </div> </div> <div> <div class="paragraph paragraph--type--clickable-icons-container paragraph--view-mode--default"> <div class="container"> <div class="row"> <div class="col p-0 text-center"> <h2>Applications</h2> </div> </div> <div class="row"> <div class="col text-center"> </div> </div> <div class="row"> <div class="row"> <div class="col-xl-2 col-lg-2 col-md-4 col-sm-6 col-6 mb-4"> <div class="paragraph paragraph--type--indvidual-clickable-icon paragraph--view-mode--default card p-3 text-center h-100 mb-0"> <a href="/resources/instrument-applications/crispr-cell-engineering-single-cell-dispenser" > <div><article> <div><img src='https://resources.bio-techne.com/bio-techne-assets/images/research-areas/single-cell-sorter-application-icon-1.png' alt='LG Application Teaser - CRISPR and iPSC cloning'></div> </article> </div> <p><strong>CRISPR and Cell Engineering</strong></p> </a> </div> </div> <div class="col-xl-2 col-lg-2 col-md-4 col-sm-6 col-6 mb-4"> <div class="paragraph paragraph--type--indvidual-clickable-icon paragraph--view-mode--default card p-3 text-center h-100 mb-0"> <a href="/resources/instrument-applications/cell-line-development-single-cell-dispenser" > <div><article> <div><img src='https://resources.bio-techne.com/bio-techne-assets/images/research-areas/single-cell-sorter-application-icon-2.png' alt='LG Application Teaser - cell line development'></div> </article> </div> <p><strong>Cell Line Development</strong></p> </a> </div> </div> <div class="col-xl-2 col-lg-2 col-md-4 col-sm-6 col-6 mb-4"> <div class="paragraph paragraph--type--indvidual-clickable-icon paragraph--view-mode--default card p-3 text-center h-100 mb-0"> <a href="/resources/instrument-applications/single-cell-genomics-single-cell-dispenser" > <div><article> <div><img src='https://resources.bio-techne.com/bio-techne-assets/images/research-areas/single-cell-sorter-application-icon-3.png' alt='LG Application Teaser - single cell genomics'></div> </article> </div> <p><strong>Single Cell Genomics</strong></p> </a> </div> </div> <div class="col-xl-2 col-lg-2 col-md-4 col-sm-6 col-6 mb-4"> <div class="paragraph paragraph--type--indvidual-clickable-icon paragraph--view-mode--default card p-3 text-center h-100 mb-0"> <a href="/resources/instrument-applications/antibody-discovery-single-cell-dispenser" > <div><article> <div><img src='https://resources.bio-techne.com/bio-techne-assets/images/research-areas/single-cell-sorter-application-icon-4.png' alt='LG Application Teaser - antibody development'></div> </article> </div> <p><strong>Antibody Discovery</strong></p> </a> </div> </div> <div class="col-xl-2 col-lg-2 col-md-4 col-sm-6 col-6 mb-4"> <div class="paragraph paragraph--type--indvidual-clickable-icon paragraph--view-mode--default card p-3 text-center h-100 mb-0"> <a href="/research-areas/immune-cell-therapy" > <div><article> <div><img src='https://resources.bio-techne.com/bio-techne-assets/images/research-areas/single-cell-sorter-application-icon-5.png' alt='LG Application Teaser - cell therapy'></div> </article> </div> <p><strong>Cell Therapy</strong></p> </a> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--section paragraph--view-mode--default mb-4"> <div> <div> <div class="paragraph paragraph--type--freeform mb-4 paragraph--view-mode--default"> <div><p><a name="models"></a></p><h2>Meet Our Single Cell Sorting Solutions</h2></div> </div> </div> <div> <div class="paragraph paragraph--type--card-paragraph paragraph--view-mode--default card-para-default"> <div class="row card_row"> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/p/cell-sorting-and-single-cell-dispensing/pala-cell-sorter-and-single-cell-dispenser_ni006" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: #f5f5f5; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/bt-pala-instrument-525x300-v2.png" alt="Bio-Techne Pala Cell Sorter and Single Cell Dispenser" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/p/cell-sorting-and-single-cell-dispensing/pala-cell-sorter-and-single-cell-dispenser_ni006" > <h3 class="card_title_htag"> <div>Pala Cell Sorter and Single Cell Dispenser</div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Configured with two lasers for up to 11 detection channels.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/p/cell-sorting-and-single-cell-dispensing/pala-cell-sorter-and-single-cell-dispenser_ni006" > View the Pala System </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/p/cell-sorting-and-single-cell-dispensing/hana-cell-sorter-and-single-cell-dispenser_ni004" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: #f5f5f5; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/bt-hana-instrument-525x300.png" alt="bio-techne hana instrument cell sorter and single cell dispenser" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/p/cell-sorting-and-single-cell-dispensing/hana-cell-sorter-and-single-cell-dispenser_ni004" > <h3 class="card_title_htag"> <div>Hana Cell Sorter and Single Cell Dispenser</div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Single laser for green and red channels.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/p/cell-sorting-and-single-cell-dispensing/hana-cell-sorter-and-single-cell-dispenser_ni004" > View the Hana System </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/search?keywords=Cell%20Sorting%20and%20Single%20Cell%20Dispensing%20Consumables&sub_category=Cell%20Sorting%20and%20Single%20Cell%20Dispensing%20Consumables&compatible_instrument=Hana&view=condensed" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: #f5f5f5; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/bt-microfluidic-cell-cartridge-525x300.png" alt="Disposable microfluidic cell cartridge used with the Bio-Techne Pala Cell Sorter and Single Cell Dispenser" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/search?keywords=Cell%20Sorting%20and%20Single%20Cell%20Dispensing%20Consumables&sub_category=Cell%20Sorting%20and%20Single%20Cell%20Dispensing%20Consumables&compatible_instrument=Hana&view=condensed" > <h3 class="card_title_htag"> <div>Microfluidic Cell Cartridges</div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Disposable cell cartridge preventing cross contamination.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/search?keywords=Cell%20Sorting%20and%20Single%20Cell%20Dispensing%20Consumables&sub_category=Cell%20Sorting%20and%20Single%20Cell%20Dispensing%20Consumables&compatible_instrument=Hana&view=condensed" > View Microfluidic Cell Cartridges </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--freeform mb-4 paragraph--view-mode--default"> <div><figure class="responsive-figure-table"><table class="table table-bordered overflow-auto"><thead><tr><th> </th><th>Hana</th><th>Pala</th></tr></thead><tbody><tr><td><strong>Laser 1</strong></td><td>488 nm</td><td>488 nm</td></tr><tr><td><strong>Laser 2</strong></td><td>N/A</td><td>405 nm or 561 nm</td></tr><tr><td><strong>Detection Channels</strong></td><td>FITC / GFP, PE / PI, Forward & Side Scatter</td><td>Up to 11 channels, Forward & Side Scatter</td></tr><tr><td><strong>Dimensions</strong></td><td>19 x 14 x 8"</td><td>25 x 14 x 9"</td></tr><tr><td><strong>Weight</strong></td><td>22 lbs</td><td>35 lbs</td></tr></tbody></table></figure></div> </div> </div> <div> <div class="paragraph paragraph--type--full-page-text-with-media mb-4 paragraph--view-mode--default"> <div> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/v2_hana-pala-model-graphic.png" alt="Hana Pala Models Graphic" loading="lazy" > </div> </div> </div> <div> <div class="paragraph paragraph--type--freeform mb-4 paragraph--view-mode--default"> <div><p><a name="resources"></a></p><h2>Featured Resources</h2></div> </div> </div> <div> <div class="paragraph paragraph--type--card-paragraph paragraph--view-mode--default card-para-default"> <div class="row card_row"> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/resources/literature/breaking-barriers-cell-engineering-with-single-cell-dispenser" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/breaking-barriers-cell-engineering-an.png" alt="Breaking Barriers in Cell Engineering" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/resources/literature/breaking-barriers-cell-engineering-with-single-cell-dispenser" > <h3 class="card_title_htag"> <div>Breaking Barriers in Cell Engineering with Single Cell Sorting Innovation</div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>This eBook, produced in collaboration with the team at Drug Target Review focuses on how advances in single cell sorting technology are furthering research in CRISPR gene editing and cell engineering. The team shares insights, looks at recent peer-reviewed publications, and talks one on one with the scientists.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/resources/literature/breaking-barriers-cell-engineering-with-single-cell-dispenser" > Download eBook </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/resources/literature/application-note-10x-genomics-workflows-with-pala-single-cell-dispenser" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/10x-genomics-workflows-an-mockup.png" alt="10x Genomics Workflow AN" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/resources/literature/application-note-10x-genomics-workflows-with-pala-single-cell-dispenser" > <h3 class="card_title_htag"> <div>10X Genomic Workflows</div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Single cell sequencing methods have emerged as powerful tools for identification of heterogeneous cell types. In this application note, we compared single-nucleus RNA sequencing (snRNA-seq) data from dissociated nuclei using traditional methods compared to sorting nuclei using the Pala cell sorter. The sequencing data showed the Pala system was able to sort nuclei to successfully clear debris from brain and kidney dissociated tissue, recover more cells for downstream 10X genomic workflows, and displays cleaner sequencing data with higher gene recognition and characterization of diverse cell types.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/resources/literature/application-note-10x-genomics-workflows-with-pala-single-cell-dispenser" > Download Application Note </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="https://resources.bio-techne.com/bio-techne-assets/docs/literature/single-cell-deposition-efficiency.pdf" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/v2_single-cell-deposition-efficiency-an.png" alt="Single Cell Deposition Efficiency AN" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="https://resources.bio-techne.com/bio-techne-assets/docs/literature/single-cell-deposition-efficiency.pdf" > <h3 class="card_title_htag"> <div>Single Cell Deposition Efficiency</div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>The limiting dilution method for deposition of single cells into well-plates is manual, low throughput and can be poorly efficient in seeding one cell per well. This can result in the need for handling of larger number of plates, making the process even more tedious and time- and reagent-consuming. Bio-techne’s single cell dispensers provide a fast and reliable alternative for single cell isolation with increased accuracy in dispensing single cells into each well while preserving cell integrity with gentle sorting pressure. The results of this comparative study serve as a reference for expected deposition efficiency with the Pala platform.</p></div> </div> <div class="card-bottom-link"> <div> <a href="https://resources.bio-techne.com/bio-techne-assets/docs/literature/single-cell-deposition-efficiency.pdf" > Download Application Note </a> </div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--section paragraph--view-mode--default mb-4"> <div> <div> <div class="paragraph paragraph--type--freeform mb-4 paragraph--view-mode--default"> <div><p><a name="scientists"></a></p></div> </div> </div> <div> <div class="paragraph paragraph--type--header"> <div> <div><h2>Hear From Other Scientists</h2></div> </div> </div> </div> <div> <div class="paragraph paragraph--type--card-paragraph paragraph--view-mode--default card-para-default"> <div class="row card_row"> <div class="col-md-6"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/resources/testimonials/from-your-peers-development-of-crispr-edited-cell-line-models-with-single-cell-dispenser" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: #f5f5f5; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/oscar-perez-leal-headshot-525x300.png" alt="Dr. Oscar Perez-Leal describes how his team leveraged a Bio-Techne Single Cell Sorter and Single Cell Dispenser to improve clonal outgrowth of CRISPR-edited cells. " loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/resources/testimonials/from-your-peers-development-of-crispr-edited-cell-line-models-with-single-cell-dispenser" > <h3 class="card_title_htag"></h3> </a> <div class="card_description flex-grow-1"> <div><p><strong>Dr. Oscar Perez-Leal from Temple University </strong>describes how his team leveraged a Bio-Techne Single Cell Dispenser to improve clonal outgrowth of CRISPR-edited cells.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/resources/testimonials/from-your-peers-development-of-crispr-edited-cell-line-models-with-single-cell-dispenser" > Read Article </a> </div> </div> </div> </div> </div> <div class="col-md-6"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/resources/literature/cell-line-development-for-biopharmaceutical-production-using-namocell-single-cell-dispenser" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: #f5f5f5; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/lina-chakrabarti-headshot-525x300.png" alt="Dr. Lina Chakrabarti from AstraZeneca discusses how the single cell sorting dispensing technology on the Pala™ system boosted cell line development workflows for biopharmaceutical manufacturing. " loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/resources/literature/cell-line-development-for-biopharmaceutical-production-using-namocell-single-cell-dispenser" > <h3 class="card_title_htag"></h3> </a> <div class="card_description flex-grow-1"> <div><p><strong>Dr. Lina Chakrabarti from AstraZeneca</strong> discusses how the single cell dispenser technology on the Pala™ system boosted cell line development workflows for biopharmaceutical manufacturing.<a name="technology"></a></p></div> </div> <div class="card-bottom-link"> <div> <a href="/resources/literature/cell-line-development-for-biopharmaceutical-production-using-namocell-single-cell-dispenser" > Read Article </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </article> </div> </div> </section> </main> </div> <div id="brandsbar-footer" class="bg-bt-primary"> <div class="container-wide container-fluid text-white"> <div class="row py-5"> <div 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