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href="/ja/solutions/biofinder-discovery-platform/info-request" class="button is-small w-button">Request more information</a></div><div id="w-node-dba77307-38d0-8b3d-acc0-c999e805f56c-08e097ba" class="page-hero_video-wrapper"><div class="w-embed w-script"><div style="max-width: 960px;"> <style> video-js.video-js.vjs-fluid:not(.vjs-audio-only-mode) { padding-top: 56.25%; } </style><video-js data-account="6415844831001" data-player="default" data-embed="default" controls="" data-video-id="6354295360112" data-playlist-id="" data-application-id="" class="vjs-fluid"></video-js> </div> <script src="https://players.brightcove.net/6415844831001/default_default/index.min.js"> </script></div></div></div></div><div class="page-hero_background-overlay"><img width="1920" height="1080" alt="Close-up of transparent spherical capsules illuminated in blue, each containing intricate, embedded structures resembling cells or circuits." loading="eager" 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background_blue-grey"><div class="w-layout-blockcontainer container w-container"><div class="section__header"><h2 class="section__title">See the CAS Content Collection™ through a biological lens</h2><div class="section__header-subhead w-richtext"><p>Designed to support the needs of biology-based inquiry, the CAS BioFinder Discovery Platform adds new data types, connections, and visualizations to the CAS Content Collection. The platform includes a new CAS BioFinder™ solution with embedded predictive models, enhanced capabilities in CAS SciFinder®, and access to comprehensive bioactivity and biomarker data through an application programming interface (API).</p></div></div></div></section><section class="section"><div class="container"><div class="content-layout grid-column-2 margin-bottom-24"><div id="w-node-b3ebee64-a457-9b20-c033-6efd85e1e7ec-08e097ba"><img src="https://cdn.prod.website-files.com/650861f00f97fe8153979335/664bab80610f1b1a1c8a58c3_hex-biofinder.webp" loading="lazy" sizes="(max-width: 991px) 100vw, (max-width: 1439px) 50vw, 720px" srcset="https://cdn.prod.website-files.com/650861f00f97fe8153979335/664bab80610f1b1a1c8a58c3_hex-biofinder-p-500.webp 500w, https://cdn.prod.website-files.com/650861f00f97fe8153979335/664bab80610f1b1a1c8a58c3_hex-biofinder-p-800.webp 800w, https://cdn.prod.website-files.com/650861f00f97fe8153979335/664bab80610f1b1a1c8a58c3_hex-biofinder-p-1080.webp 1080w, https://cdn.prod.website-files.com/650861f00f97fe8153979335/664bab80610f1b1a1c8a58c3_hex-biofinder-p-1600.webp 1600w, https://cdn.prod.website-files.com/650861f00f97fe8153979335/664bab80610f1b1a1c8a58c3_hex-biofinder.webp 2048w" alt="Human cells"/></div><div class="content-blockquote_component"><blockquote class="content-blockquote">"CAS BioFinder provides a centralized database for drug discovery. It tells you everything that’s been published in patents and literature and has associated pharmacology pathways, metabolism, and nearby chemical neighbors. A lot of people in drug discovery are going to different databases for each line function, but CAS BioFinder is a nice way of centralizing that."</blockquote><div class="w-richtext"><p><strong>Structural biologist, CAS BioFinder development partner</strong></p></div></div></div></div></section><div class="section background_blue-grey"><div class="w-layout-blockcontainer container w-container"><h2>What is the CAS BioFinder Discovery Platform?‍</h2><h3>CAS BioFinder™<br/></h3><p>Working through the literature to find disease targets, plan structure-activity relationship studies, and assess the potential for off-target interactions takes time and risks missing key information. <br/><br/>With CAS BioFinder, you can quickly access the verified data you need along with predicted bioactivity data, all derived from the existing literature—ensuring confidence that you always have the most relevant results. <br/><br/>Our expert scientists have combed through the literature and patents, extracted the data relevant to drug discovery scientists, and connected related data points so that you can quickly answer your drug discovery questions. This commitment to manual curation by CAS experts means you can trust the quality of the insights you uncover. <br/><br/>Leverage existing and predicted bioactivity, ligand, sequence, and biomarker data, all accessible from the streamlined CAS BioFinder user interface, to save time and accelerate your drug discovery program. </p><a href="/ja/solutions/biofinder-discovery-platform/info-request" class="button is-small w-button">Request information about CAS BioFinder</a></div></div><section class="section"></section><section class="section"><div class="container"><div class="grid-column-2"><div id="w-node-_6c1bcb6d-dda1-296b-4ff9-6f54516825db-08e097ba"><h4>Move faster with API access </h4><div class="w-richtext"><p>Streamline your drug discovery workflows with API access to high-quality, harmonized, and renowned CAS data, including normalized bioactivity and biomarker data. </p></div></div><div><h4>Complete your workflows with CAS SciFinder</h4><div class="w-richtext"><p>Leverage the integrated capabilities of CAS SciFinder and CAS BioFinder for deep dives into reference material, biological sequence data, retrosynthesis planning, and analytical methods.</p></div></div></div></div></section><section class="section"><div class="container"><div class="cta__dark"><div class="cta__dark-content"><h2 class="cta__dark-title">Discover more about the world-class data powering this new platform.</h2><div class="cta__button-wrapper"><a href="/ja/cas-data/life-sciences-data" class="button is-small w-button">Explore CAS life sciences data</a></div></div><img src="https://cdn.prod.website-files.com/650861f00f97fe8153979335/655cf3c831d55db466d467e6_long-hex-left__bottom.svg" loading="lazy" width="141.5" alt="" class="cta__dark-accent_bottom-left"/><img src="https://cdn.prod.website-files.com/650861f00f97fe8153979335/655cf3c83233bc880f83e322_long-hex-right__top.svg" loading="lazy" width="145" alt="" class="cta__dark-accent_bottom-right"/></div></div></section><section class="section background_blue-grey"><div class="container"><div class="section__header"><h2 class="section__title">Answer critical drug discovery questions</h2></div><div class="w-layout-grid grid-column-2"><div class="card_video"><div id="w-node-cdd2753f-92ee-6545-cde7-b8916e0d9b56-08e097ba" class="video-wrapper"><div class="w-embed w-script"><div style="max-width: 960px;"> <style> video-js.video-js.vjs-fluid:not(.vjs-audio-only-mode) { padding-top: 56.25%; } </style><video-js data-account="6415844831001" data-player="default" data-embed="default" controls="" data-video-id="6354038219112" data-playlist-id="" data-application-id="" class="vjs-fluid"></video-js> </div> <script src="https://players.brightcove.net/6415844831001/default_default/index.min.js"> </script></div></div><div class="card_video-body"><h3 itemprop="name" class="card__title">What scaffolds and molecules are associated with this disease?</h3></div></div><div id="w-node-_82035e60-c8ea-f1fb-02c0-e45f61dc6f13-08e097ba" class="card_video"><div id="w-node-_82035e60-c8ea-f1fb-02c0-e45f61dc6f14-08e097ba" class="video-wrapper"><div class="w-embed w-script"><div style="max-width: 960px;"> <style> video-js.video-js.vjs-fluid:not(.vjs-audio-only-mode) { padding-top: 56.25%; } </style><video-js data-account="6415844831001" data-player="default" data-embed="default" controls="" data-video-id="6354944434112" data-playlist-id="" data-application-id="" class="vjs-fluid"></video-js> </div> <script src="https://players.brightcove.net/6415844831001/default_default/index.min.js"> </script></div></div><div class="card_video-body"><h3 itemprop="name" class="card__title">What molecules are likely to interact with this target?</h3></div></div><div id="w-node-b5c33ca7-8a12-acad-ff8d-88b73229e819-08e097ba" class="card_video"><div id="w-node-b5c33ca7-8a12-acad-ff8d-88b73229e81a-08e097ba" class="video-wrapper"><div class="w-embed w-script"><div style="max-width: 960px;"> <style> video-js.video-js.vjs-fluid:not(.vjs-audio-only-mode) { padding-top: 56.25%; } </style><video-js data-account="6415844831001" data-player="default" data-embed="default" controls="" data-video-id="6354036843112" data-playlist-id="" data-application-id="" class="vjs-fluid"></video-js> </div> <script src="https://players.brightcove.net/6415844831001/default_default/index.min.js"> </script></div></div><div class="card_video-body"><h3 itemprop="name" class="card__title">What targets are likely to interact with this molecule?</h3></div></div><div id="w-node-_427b7ffc-5da1-c0c2-b8ab-8e86e678c280-08e097ba" class="card_video"><div id="w-node-_427b7ffc-5da1-c0c2-b8ab-8e86e678c281-08e097ba" class="video-wrapper"><div class="w-embed w-script"><div style="max-width: 960px;"> <style> video-js.video-js.vjs-fluid:not(.vjs-audio-only-mode) { padding-top: 56.25%; } </style><video-js data-account="6415844831001" data-player="default" data-embed="default" controls="" data-video-id="6354298655112" data-playlist-id="" data-application-id="" class="vjs-fluid"></video-js> </div> <script src="https://players.brightcove.net/6415844831001/default_default/index.min.js"> </script></div></div><div class="card_video-body"><h3 itemprop="name" class="card__title">What biomarkers are relevant to this disease?</h3></div></div></div></div></section><section class="section testimonial-section-dark"><div class="testimonial__container"><div class="testimonial__wrapper"><blockquote class="testimonial__blockquote">"CAS BioFinder has been a very useful tool, especially for identifying ligands or scaffolds of interest and discovering similar ligands and the targets that they inhibit. The ease of finding references for compounds actually helped us understand more about a possible new target on which our ligand acted in phenotypic assays."</blockquote><div class="w-layout-vflex"><div class="testimonial__author-name">CAS BioFinder development partner</div></div></div></div></section><section class="section section-features"><div class="container"><h2 class="text-color-light_blue">Capabilities designed for your drug discovery success<br/></h2><div class="grid-column-3"><div class="card__feature"><div class="card__feature--left-border"></div><div class="card__feature--content"><div class="card__feature-icon-wrapper"><img src="https://cdn.prod.website-files.com/650861f00f97fe8153979335/665f6336fe67c9e8b23a2c99_Discover-Biological-BioFinder-ico.svg" loading="lazy" width="92" height="92" alt="" class="card__feature-icon"/></div><div class="rich-text_features w-richtext"><p>Search by target, disease, ligand, or molecular structure to analyze detailed bioactivity data and identify new drug development opportunities. </p></div></div></div><div class="card__feature"><div class="card__feature--left-border"></div><div class="card__feature--content"><div class="card__feature-icon-wrapper"><img src="https://cdn.prod.website-files.com/650861f00f97fe8153979335/665f751dadd5ea0d449987d8_DECIPHER-BioFinder-icon.svg" loading="lazy" width="92" height="92" alt="" class="card__feature-icon"/></div><div class="rich-text_features w-richtext"><p>Find and explore targets quickly with a detailed breakdown of the relationships between diseases, pathways, targets, and ligands.</p></div></div></div><div class="card__feature"><div class="card__feature--left-border"></div><div class="card__feature--content"><div class="card__feature-icon-wrapper"><img src="https://cdn.prod.website-files.com/650861f00f97fe8153979335/665f62dceee229fc07092100_scaffold-BioFinder-icon.svg" loading="lazy" width="92" height="92" alt="" class="card__feature-icon"/></div><div class="rich-text_features w-richtext"><p>Drive efficient SAR exploration with a comprehensive scaffold search to help you identify ligands linked to published and predicted bioactivity data.</p></div></div></div><div class="card__feature"><div class="card__feature--left-border"></div><div class="card__feature--content"><div class="card__feature-icon-wrapper"><img src="https://cdn.prod.website-files.com/650861f00f97fe8153979335/665f7552c95d680bd4147742_Ai-BioFinder-ico.svg" loading="lazy" width="92" height="92" alt="" class="card__feature-icon"/></div><div class="rich-text_features w-richtext"><p>Expose hidden interactions between ligands and their protein targets and connected pathways by leveraging predictive analytics, machine learning, and neural networks.</p></div></div></div><div class="card__feature"><div class="card__feature--left-border"></div><div class="card__feature--content"><div class="card__feature-icon-wrapper"><img src="https://cdn.prod.website-files.com/650861f00f97fe8153979335/665f75d740dc93c9075a31d6_Analyze-BioFinder-ico.svg" loading="lazy" width="92" height="92" alt="" class="card__feature-icon"/></div><div class="rich-text_features w-richtext"><p>Identify targets and associated pharmacology data for any known or novel molecule, and filter results by functions like inhibitor, modulator, and agonist.</p></div></div></div><div class="card__feature"><div class="card__feature--left-border"></div><div class="card__feature--content"><div class="card__feature-icon-wrapper"><img src="https://cdn.prod.website-files.com/650861f00f97fe8153979335/665f76534e07f61753752573_Off-Target-BioFinder-icon.svg" loading="lazy" width="92" height="92" alt="" class="card__feature-icon"/></div><div class="rich-text_features w-richtext"><p>Advance drug candidates confidently with innovative prediction models that forecast off-target interactions for any ligand to maximize safety and minimize 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class="section__header"><h2 class="section__title">See how we’re thinking about drug discovery</h2></div><div class="grid-column-3"><div typeof="Article" vocab="" id="w-node-a20cb0dd-b9df-6a0b-dbc5-c6732757fde8-2757fde8" class="card"><img class="card__image" src="https://cdn.prod.website-files.com/650861f00f97fe8153979335/664ba2a124b22ee9cdd27f1f_CAS_INSIGHTS_20231201143622_5DA_0776%20(1).webp" width="1024" height="576" alt="" sizes="(max-width: 767px) 100vw, (max-width: 991px) 50vw, (max-width: 1439px) 33vw, 480px" property="image" loading="lazy" srcset="https://cdn.prod.website-files.com/650861f00f97fe8153979335/664ba2a124b22ee9cdd27f1f_CAS_INSIGHTS_20231201143622_5DA_0776%20(1)-p-500.webp 500w, https://cdn.prod.website-files.com/650861f00f97fe8153979335/664ba2a124b22ee9cdd27f1f_CAS_INSIGHTS_20231201143622_5DA_0776%20(1)-p-800.webp 800w, https://cdn.prod.website-files.com/650861f00f97fe8153979335/664ba2a124b22ee9cdd27f1f_CAS_INSIGHTS_20231201143622_5DA_0776%20(1)-p-1080.webp 1080w, 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https://cdn.prod.website-files.com/650861f00f97fe8153979335/664ba3718ceb3e807c069a67_jefferson_parker_1920x1080_0.webp 1600w"/><div class="card__body"><div class="card__webinar-block"></div><a itemprop="url" href="https://www.cas.org/resources/cas-insights/challenges-and-opportunities-in-sequence-analysis-during-drug-discovery" target="_blank" class="card__title-link w-inline-block"><h2 property="headline" class="card__title">Challenges and opportunities of sequence analysis during drug discovery</h2></a><div itemprop="description" class="card__summary-text-field">Jefferson Parker, Ph.D., NullSet Informatics Solutions, shares the importance of sequence analysis, how AI technologies could improve it, and the key problems that remain.</div><div class="card__date-meta-block"></div><div class="card__feature-solution--wrapper"></div></div><div class="button-wrapper button-wrapper-full-width"><a 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https://cdn.prod.website-files.com/650861f00f97fe8153979335/664ba373b60fae3a0b330085_ben-r-taft-1920x1080.webp 1600w"/><div class="card__body"><div class="card__webinar-block"></div><a itemprop="url" href="https://www.cas.org/resources/cas-insights/challenges-and-opportunities-in-structure-activity-relationship-sar-studies" target="_blank" class="card__title-link w-inline-block"><h2 property="headline" class="card__title">Challenges and opportunities of structure-activity-relationship (SAR) studies</h2></a><div itemprop="description" class="card__summary-text-field">Ben R. 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