MRS 1754 (CAS 264622-58-4): R&D Systems

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class="ds_title_table"> <h1 class="ds_title">MRS 1754 </h1> <div class="dsSprite_tocris ds_brand_logo ds_tocris_logo"></div> </div> <div class="product_meta"> <span class="category_number">Catalog #: 2752</span> <br/> <span class="citations"> <a href="#product-citations" id="citation_count" class="jump_to" data-tab="3" data-tabname="product-citations"> 16 Citations </a> </span> <a href="/reviews/2752" rel="nofollow"><span class="submit_review"><button class="btn btn-quaternary">Submit a Review</button></span></a> <span class="datasheet_link"> <a href="#product-datasheets">Datasheet / COA / SDS</a> </span> </div>  <div class="product_wrapper row"> <div class="product_ordering_wrapper col-xs-12 col-md-8 col-md-push-4"> <div class="product_ordering"> <form action="/products/mrs-1754_2752" method="post" id="atc-datasheet-form" accept-charset="UTF-8"><div><div id="atc_datasheet_block">     <table class="add_to_cart"> <thead> <tr> <th class="ds_catalog">Catalog #</th> <th class="ds_availability_column mobile-hide">Availability</th> <th class="ds_size_price_column">Size / Price</th> <th class="ds_quantity_column">Qty</th> </tr> </thead> <tbody> <tr class="et_atc_product" data-sku="2752/10"> <td class="dat_catalog_column">2752/10</td> <td class="et_atc_results" colspan="2"></td> <td class="ds_quantity ds_quantity_column"><div class="form-item form-item-catnum-27522f10 form-type-textfield form-group"><input class="atc_quantity atc_hidden atc_qty form-control form-text" placeholder="0" style="display:none;" type="text" id="edit-catnum-27522f10" name="catnum-2752%2F10" value="" size="5" maxlength="3" /></div></td> </tr> </tbody> </table> <div class="ds_atc_pre_buttons"></div> <div class="ds_atc_buttons"> <a href="/quote/instruments/ella-automated-immunoassay-system" class="btn btn-secondary atc_request_quote_simple_plex_assay" style="display:none" rel="nofollow">Request a Quote</a> <a href="/services/bulk-quote-request?catnum=2752&product=MRS 1754" class="btn btn-secondary atc_hidden bulk_btn" style="display:none;" rel="nofollow" title="Competitive discounts on products purchased in bulk quantities">Bulk Orders</a> <button class="btn btn-primary atc_hidden atc_btn form-submit icon-before" style="display:none;" title="Enter quantities above and click to add to cart" type="submit" id="edit-add-to-cart" name="add_to_cart_btn" value="Add to Cart"><span class="icon glyphicon glyphicon-plus" aria-hidden="true"></span> Add to Cart</button> </div> <div class="ds_atc_post_buttons"></div> </div> <input type="hidden" name="form_build_id" value="form-ffkZHyaixMGUbcvu_FkVKpOF2eXZSDR2koII16oWAKE" /> <input type="hidden" name="form_id" value="atc_datasheet_form" /> </div></form> </div> </div> <div class="product_image_wrapper col-xs-12 col-md-4 col-md-pull-8"> <div class="product_image tocris_product_image"> <span class="product_image_label"> </span> <a class="ds-image overview-images" data-toggle="lightbox" data-gallery="overview-images" onClick="event.preventDefault();" data-title="MRS 1754 | CAS No. 264622-58-4 | Adenosine A2b Receptor Antagonists" data-footer="MRS 1754 | CAS No. 264622-58-4" title="Cat. No. 2752 - MRS 1754" href="https://resources.rndsystems.com/images/datasheets/structures/mrs-1754_2752.png"> <img fetchpriority="high" src="https://resources.rndsystems.com/images/datasheets/structures/mrs-1754_2752.png" class="img-fluid" alt="MRS 1754 | CAS No. 264622-58-4 | Adenosine A2b Receptor Antagonists" title="MRS 1754 | CAS No. 264622-58-4 | Adenosine A2b Receptor Antagonists"> </a> <div class="search_image_other_count"> <span class="search_more_images">1 Image</span> </div> </div> </div> <div id="extra_images overview-images" class="hidden"> </div> </div> <div class="product_info_wrapper"> <div class="product_info"> <strong>Description:</strong> Selective A2B antagonist </div> <p class="extended_details_chemical_name"> <strong>Chemical Name:</strong> <em>N</em>-(4-Cyanophenyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1<em>H</em>-purin-8-yl)phenoxy]-acetamide </p> <p class="extended_details_purity"> <strong>Purity:</strong> ≥98%</p> </div> <div id="view-more-target" class="datasheet_section_element"> View <a href="/target/adenosine-a2b-receptor-antagonists">All Products for Adenosine A2b Receptor Antagonists</a> </div> </div> <div class="tabbed_content" id="rnd_tocris"> <div id="ds_tabs" class="tab_menu"> <div class="tab tab_1 tab_open" data-tab="1" data-tabname="product-details" id="dsTabs_product-details"> <span>Product Details</span> </div> <div class="tab tab_3" data-tab="3" data-tabname="product-citations" id="dsTabs_product-citations"> <span>Citations (16)</span> </div> <div class="tab tab_5" data-tab="5" data-tabname="supplemental-products" id="dsTabs_supplemental-products"> <span>Supplemental Products</span> </div> <div class="tab tab_6" data-tab="6" data-tabname="product-reviews" id="dsTabs_product-reviews"> <span> Reviews </span> </div> </div> <div class="tab_content tab_1 tab_open" data-tab="1" data-tabname="product-details" id="product-details"> <div class="datasheet_section_element"> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_biological_activity" id="product-anchor-ds_biological_activity">Biological Activity</a> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_technical_data" id="product-anchor-ds_technical_data"> Technical Data</a> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_additional_information" id="product-anchor-ds_additional_information">Additional Information</a> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_background" id="product-anchor-ds_background">Background</a> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_datasheets" id="product-anchor-ds_datasheets"> Product Datasheets</a> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_calculator" id="product-anchor-ds_calculator">Calculators</a> </div> <div id="ds_biological_activity" class="datasheet_section"> <h2>Biological Activity</h2> MRS 1754 is a selective adenosine A<sub>2B</sub> receptor antagonist (K<sub>i</sub> values are 1.97, 16.8, 403, 503, 570 and 612 nM for hA<sub>2B</sub>, rA<sub>1</sub>, hA<sub>1</sub>, hA<sub>2A</sub>, hA<sub>3</sub> and rA<sub>2A</sub> receptors respectively). </div> <div id="ds_technical_data" class="datasheet_section"> <h2>Technical Data</h2> <div class="ds_table summary_table"> <div class="ds_table_body"> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">M.Wt:</div> <div class="ds_table_cell summary_table_data">486.52</div> </div> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">Formula:</div> <div class="ds_table_cell summary_table_data">C<sub>26</sub>H<sub>26</sub>N<sub>6</sub>O<sub>4</sub></div> </div> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">Solubility:</div> <div class="ds_table_cell summary_table_data">Soluble to 5 mM in DMSO with gentle warming</div> </div> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">Purity:</div> <div class="ds_table_cell summary_table_data">≥98%</div> </div> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">Storage:</div> <div class="ds_table_cell summary_table_data">Desiccate at RT</div> </div> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">CAS No:</div> <div class="ds_table_cell summary_table_data">264622-58-4</div> </div> </div> </div> <p class="small"> The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.<br/> Tocris products are intended for laboratory research use only, unless stated otherwise. </p> </div> <div id="customer_also_purchased_block" class="loader" data-catalogId="2752"></div> <div id="ds_additional_information" class="datasheet_section"> <h2>Additional Information</h2> <div class="ds_table summary_table"> <div class="ds_table_body"> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">Licensing Caveats:</div> <div class="ds_table_cell summary_table_data">Sold with the permission of the University of Virginia Patent Foundation</div> </div> </div> </div > </div> <div id="ds_background" class="datasheet_section"> <h2>Background References</h2> <ol class="tocris_background_refs"> <li> <a href="http://www.ncbi.nlm.nih.gov/pubmed/29771938" target="_blank" rel="noreferrer nofollow" class="safe_link"> Ability of ?? T cells to modulate the Foxp3 T cell response is dependent on adenosine </a> <br/> D Liang, JI Woo, H Shao, WK Born, RL O'Brien, HJ Kaplan, D Sun<br/> PLoS ONE, 2018;13(5):e0197189. </li> <li> <a href="http://www.ncbi.nlm.nih.gov/pubmed/26355158" target="_blank" rel="noreferrer nofollow" class="safe_link"> IFN-gamma Prevents Adenosine Receptor (A2bR) Upregulation To Sustain the Macrophage Activation Response. </a> <br/> Cohen H, Ward A, Hamidzadeh K, Ravid K, Mosser D<br/> J Immunol, 2015;195(8):3828-37. </li> <li> <a href="http://www.ncbi.nlm.nih.gov/pubmed/23682121" target="_blank" rel="noreferrer nofollow" class="safe_link"> Adenosine regulates bone metabolism via A1, A2A, and A2B receptors in bone marrow cells from normal humans and patients with multiple myeloma. </a> <br/> He W, Mazumder A, Wilder T, Cronstein B<br/> FASEB J, 2013;27(9):3446-54. </li> <li> <a href="http://www.ncbi.nlm.nih.gov/pubmed/10737749" target="_blank" rel="noreferrer nofollow" class="safe_link"> Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent and selective antagonists at human A<sub>2B</sub> adenosine receptors. </a> <br/> Kim et al.<br/> J.Med.Chem., 2000;43:1165 </li> <li> <a href="http://www.ncbi.nlm.nih.gov/pubmed/11266650" target="_blank" rel="noreferrer nofollow" class="safe_link"> [<sup>3</sup>H]MRS 1754, a selective antagonist radioligand for A<sub>2B</sub> adenosine receptors. </a> <br/> Ji et al.<br/> Biochem.Pharmacol., 2001;61:657 </li> <li> Adenosine receptor activation ameliorates type I diabetes. <br/> Nemeth et al.<br/> FASEB J., 2007;21:2380 </li> </ol> </div> <div class="datasheet_section" id="product-datasheets"> <h2 id="ds_datasheets">Product Datasheets</h2> <div class="product_datasheets tocris_docs" id="product-datasheets"> <div class="row"> <div class="col-sm-12 col-md-6"> <div class="ds_document"> <a class="coa_url safe_link" href="//resources.rndsystems.com/pdfs/tocris_coa/2752_6_coa.pdf?t=1732691810" target="_blank">COA view current batch</a> </div> <div class="ds_document"> <span class="tocris_cofa_select"> Or select another batch: <div class="select_wrapper"> <select id="cofasel"> <option value="//resources.rndsystems.com/pdfs/tocris_coa/2752_6_coa.pdf?1732691810">6</option> <option value="//resources.rndsystems.com/pdfs/tocris_coa/2752_5_coa.pdf?1732691810">5</option> <option value="//resources.rndsystems.com/pdfs/tocris_coa/2752_4_coa.pdf?1732691810">4</option> <option value="//resources.rndsystems.com/pdfs/tocris_coa/2752_3_coa.pdf?1732691810">3</option> <option value="//resources.rndsystems.com/pdfs/tocris_coa/2752_2_coa.pdf?1732691810">2</option> <option value="//resources.rndsystems.com/pdfs/tocris_coa/2752_1_coa.pdf?1732691810">1</option> </select> </div> <a class="btn btn-quinary coa_rnd_button safe_link" id="coa_view_batch" href="//resources.rndsystems.com/pdfs/tocris_coa/2752_6_coa.pdf?t=1732691810" target="blank">View Batch</a> </span> </div> <div class="visible-xs-block visible-sm-block datasheet_section_element"></div> </div> <div class="col-sm-12 col-md-6"> <div class="ds_document sds_link"> <a href="//resources.rndsystems.com/pdfs/tocris_msds/2752_sds.pdf?1732691810" class="safe_link" id="tocris_sds_lnk" target="_blank">SDS</a> </div> </div> </div> </div> </div> <div id="ds_calculator" class="datasheet_section"> <div id="btn_calculator_wrapper"><div class="datasheet_calculator_toggle btn btn-secondary" id="btn_reconstitution">Reconstitution Calculator</div><div class="datasheet_calculator_toggle btn btn-secondary" id="btn_molarity">Molarity Calculator</div></div><div id="datasheet_calculators"><div id="btn_reconstitution_calc" class="datasheet_calculator"><h2>Reconstitution Calculator</h2><div id="reconstitution_calculator" class="calculator"> <form id="recCalc"> <div class="reconstitution_calculator_text" id="reconstitution_calculator_instructions"> <p>The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.</p> </div> <div class="calc_section"> <label for="reconstitution_calculator_volume" class="calculator_label">Volume (to add to vial)</label> <input id="reconstitution_calculator_volume" name="reconstitution_calculator_volume" type="text" maxlength="16" placeholder="volume" class="calculator_input calculator_text"/> <span class="select_wrapper"> <select id="reconstitution_calculator_volume_unit" class="calculator_input calculator_select"> <option value="ml">ml</option> <option value="ul" selected="selected">ul</option> </select> </span> </div> <span class="calculator_equals calculator_operator">=</span> <div class="calc_section"> <label for="reconstitution_calculator_mass" class="calculator_label">Mass (in vial)</label> <input id="reconstitution_calculator_mass" name="reconstitution_calculator_mass" type="text" maxlength="16" placeholder="mass" class="calculator_input calculator_text"/> <span class="select_wrapper"> <select id="reconstitution_calculator_mass_unit" class="calculator_input calculator_select"> <option value="mg">mg</option> <option value="ug" selected="selected">ug</option> <option value="ng">ng</option> </select> </span> </div> <span class="calculator_divide calculator_operator">÷</span> <div class="calc_section"> <label for="reconstitution_calculator_concentration" class="calculator_label">Desired Reconstitution Concentration</label> <input id="reconstitution_calculator_concentration" name="reconstitution_calculator_concentration" type="text" maxlength="16" placeholder="conc." class="calculator_input calculator_text"/> <span class="select_wrapper"> <select id="reconstitution_calculator_concentration_unit" class="calculator_input calculator_select"> <option value="mg/ml">mg/ml</option> <option value="ug/ml" selected="selected">ug/ml</option> <option value="ng/ml">ng/ml</option> </select> </span> </div> <div id="reconstitution_foot" class="calc_section"> <input type="submit" value="Calculate" id="button_reconstitution_calculator_calculate" class="calculator_button btn btn-secondary"/> </div> </form> </div> </div><div id="btn_molarity_calc" class="datasheet_calculator"><h2>Molarity Calculator</h2><div class="molarity_framework"> <div id="molarity_calculator" class="calculator"> <form id="molCalc"> <div class="calc_section"> <label for="molarity_calculator_mass" class="calculator_label">Mass</label> <input id="molarity_calculator_mass" name="molarity_calculator_mass" type="text" maxlength="6" placeholder="mass" class="calculator_input calculator_text"/> <span class="select_wrapper"> <select id="molarity_calculator_mass_unit" class="calculator_input calculator_select" name="molarity_calculator_mass_unit"> <option value="-12">picograms</option> <option value="-9">nanograms</option> <option value="-6">micrograms</option> <option value="-3" selected>milligrams</option> <option value="0">grams</option> <option value="3">kilograms</option> </select> </span> </div> <span class="calculator_equals calculator_operator">=</span> <div class="calc_section"> <label for="molarity_calculator_concentration" class="calculator_label">Concentration</label> <input id="molarity_calculator_concentration" name="molarity_calculator_concentration" type="text" maxlength="6" placeholder="conc." class="calculator_input calculator_text"/> <span class="select_wrapper"> <select id="molarity_calculator_concentration_unit" class="calculator_input calculator_select" name="molarity_calculator_concentration_unit"> <option value="-15">femtomolar</option> <option value="-12">picomolar</option> <option value="-9">nanomolar</option> <option value="-6">micromolar</option> <option value="-3" selected>millimolar</option> <option value="0">molar</option> </select> </span> </div> <span class="calculator_multiply calculator_operator">x</span> <div class="calc_section"> <label for="molarity_calculator_volume" class="calculator_label">Volume</label> <input id="molarity_calculator_volume" name="molarity_calculator_volume" type="text" maxlength="6" placeholder="volume" class="calculator_input calculator_text"/> <span class="select_wrapper"> <select id="molarity_calculator_volume_unit" class="calculator_input calculator_select" name="molarity_calculator_volume_unit"> <option value="-9">nanoliter</option> <option value="-6">microliter</option> <option value="-3" Selected>milliliter</option> <option value="0">liter</option> </select> </span> </div> <span class="calculator_multiply calculator_operator">x</span> <div class="calc_section"> <label for="molarity_calculator_molecular_weight" class="calculator_label">M. Wt*</label> <input id="molarity_calculator_molecular_weight" name="molarity_calculator_molecular_weight" type="text" maxlength="6" placeholder="mwt" class="calculator_input calculator_text" value="486.52"/> <span class="calculator_unit_label">g/mol</span> </div> <div id="molarity_foot" class="calc_section"> <input type="submit" value="Calculate" id="button_molarity_calculator_calculate" class="calculator_button btn btn-secondary"/> </div> <div> <p>*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).</p> </div> </form> </div> </div> </div></div> </div> </div> <div class="tab_content tab_3" data-tab="3" data-tabname="product-citations" id="citations"> <a id="citations_section"></a> <h2><span class="citations">Citations for MRS 1754</h2> <div id="citation"> <a id="dsTabCitations"></a> <p> The citations listed below are publications that use Tocris products. Selected citations for MRS 1754 include: </p> <p> <strong><span id="maxcitations">16</span> Citations: Showing <span id="showfrom">1</span> - <span id="showto">10</span> </strong> </p> <div class="row"> <ol id="citations" class="col-xs-12" data-expandall="false" data-max-citations="16" data-max-show="10"> <li class="top-lined" data-species="" data-application="" data-sampletype=""> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/29935155"> Adenosine binds predominantly to adenosine receptor A<sub>1</sub> subtype in astrocytes and mediates an immunosuppressive effect. </a> </span><br/> Authors: Liu Et al.<br/> Brain Res  2018;1700:47 <br/> </li> <li class="top-lined" data-species="" data-application="" data-sampletype=""> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/28054654"> Aminophylline suppresses stress-induced visceral hypersensitivity and defecation in irritable bowel syndrome. </a> </span><br/> Authors: Asano<br/> Scientific Reports  2017;7:40214 <br/> </li> <li class="top-lined" data-species="" data-application="" data-sampletype=""> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/28502661"> An Adenosine Receptor for Olfaction in Fish. </a> </span><br/> Authors: Wakisaka Et al.<br/> Curr Biol  2017;27:1437 <br/> </li> <li class="top-lined" data-species="" data-application="" data-sampletype=""> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/27577957"> Adenosine arrests breast cancer cell motility by A3 receptor stimulation. </a> </span><br/> Authors: Ledderose Et al.<br/> Purinergic Signalling  2016; <br/> </li> <li class="top-lined" data-species="" data-application="" data-sampletype=""> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/25632271"> Anti-inflammatory effects of adenosine N1-oxide. </a> </span><br/> Authors: Kohno Et al.<br/> Am J Physiol Lung Cell Mol Physiol  2015;12:2 <br/> </li> <li class="top-lined" data-species="" data-application="" data-sampletype=""> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/26446689"> Adenosine A2B receptor activation stimulates glucose uptake in the mouse forebrain. </a> </span><br/> Authors: Lemos Et al.<br/> Purinergic Signal  2015;11:561 <br/> </li> <li class="top-lined" data-species="" data-application="" data-sampletype=""> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/25473378"> Positive allosteric modulation of the adenosine A2a receptor attenuates inflammation. </a> </span><br/> Authors: Welihinda and Amento<br/> J Inflamm (Lond)  2014;11:37 <br/> </li> <li class="top-lined" data-species="" data-application="" data-sampletype=""> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/23682121"> Adenosine regulates bone metabolism via A1, A2A, and A2B receptors in bone marrow cells from normal humans and patients with multiple myeloma. </a> </span><br/> Authors: He Et al.<br/> FASEB J  2013;27:3446 <br/> </li> <li class="top-lined" data-species="" data-application="" data-sampletype=""> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/23638679"> Functional interaction between pre-synaptic α6β2-containing nicotinic and adenosine A2A receptors in the control of DA release in the rat striatum. </a> </span><br/> Authors: Gar&ccedil;&atilde;o Et al.<br/> Br J Pharmacol  2013;169:1600 <br/> </li> <li class="top-lined" data-species="" data-application="" data-sampletype=""> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/22787201"> Imiquimod suppresses propagation of herpes simplex virus 1 by upregulation of cystatin A via the adenosine receptor A1 pathway. </a> </span><br/> Authors: Kan Et al.<br/> J Virol  2012;86:10338 <br/> </li> <div id="ds_extra_cits"> <li class="top-lined" data-species="" data-application="" data-sampletype=""> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/21966389"> IL-4 amplifies the pro-inflammatory effect of adenosine in human mast cells by changing expression levels of adenosine receptors. </a> </span><br/> Authors: Hua Et al.<br/> PLoS One  2011;6:e24947 <br/> </li> <li class="top-lined" data-species="" data-application="" data-sampletype=""> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/21799929"> Interleukin-6 contributes to inflammation and remodeling in a model of adenosine mediated lung injury. </a> </span><br/> Authors: Pedroza Et al.<br/> Mol Vis  2011;6:e22667 <br/> </li> <li class="top-lined" data-species="" data-application="" data-sampletype=""> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/21743001"> Adenosine A2A and A2B receptors are both required for adenosine A1 receptor-mediated cardioprotection. </a> </span><br/> Authors: Zhan Et al.<br/> Am J Physiol Heart Circ Physiol  2011;301:H1183 <br/> </li> <li class="top-lined" data-species="" data-application="" data-sampletype=""> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/20531463"> Adenosine can mediate its actions through generation of reactive oxygen species. </a> </span><br/> Authors: Gebremedhin Et al.<br/> J Cereb Blood Flow Metab  2010;30:1777 <br/> </li> <li class="top-lined" data-species="" data-application="" data-sampletype=""> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/19684202"> Effect of ventilation pressure on alveolar fluid clearance and β-agonist responses in mice. </a> </span><br/> Authors: Yu Et al.<br/> Am J Respir Crit Care Med  2009;297:L785 <br/> </li> <li class="top-lined" data-species="" data-application="" data-sampletype=""> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/18689466"> Influenza A virus inhibits alveolar fluid clearance in BALB/c mice. </a> </span><br/> Authors: Wolk Et al.<br/> PLoS One  2008;178:969 <br/> </li> </div> </ol> </div> <div class="clearfix"><button class="btn btn-quinary ds_extra_cits pull-right toggle_cits_down" id="toggle_cits"></button></div> </div> </div> <div class="tab_content tab_4" data-tab="4" data-tabname="product-faqs" id="product-faqs"> <h2>FAQs</h2> 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MRS 1754 (CAS 264622-58-4): R&D Systems