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vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Patogeneza_i_simptomi"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Patogeneza i simptomi</span> </div> </a> <ul id="toc-Patogeneza_i_simptomi-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Povezano" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Povezano"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Povezano</span> </div> </a> <ul id="toc-Povezano-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Literatura" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Literatura"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Literatura</span> </div> </a> <ul id="toc-Literatura-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Sadržaj" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" lang="sh-Latn" dir="ltr"> <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Prikaži/sakrij sadržaj" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Prikaži/sakrij sadržaj</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading" lang="sh-Latn" dir="ltr"><span class="mw-page-title-main">Tetanus</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" lang="sh-Latn" dir="ltr"> <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Prijedi na druge jezične varijante članka. Dostupno je na 93 jezika" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-93" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">93 jezika</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-af mw-list-item"><a href="https://af.wikipedia.org/wiki/Klem-in-die-kaak" title="Klem-in-die-kaak — Afrikanerski" lang="af" hreflang="af" data-title="Klem-in-die-kaak" data-language-autonym="Afrikaans" data-language-local-name="Afrikanerski" class="interlanguage-link-target"><span>Afrikaans</span></a></li><li class="interlanguage-link interwiki-an mw-list-item"><a href="https://an.wikipedia.org/wiki/Tetanos" title="Tetanos — Aragonežanski" lang="an" hreflang="an" data-title="Tetanos" data-language-autonym="Aragonés" data-language-local-name="Aragonežanski" class="interlanguage-link-target"><span>Aragonés</span></a></li><li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D9%83%D8%B2%D8%A7%D8%B2" title="كزاز — Arapski" lang="ar" hreflang="ar" data-title="كزاز" data-language-autonym="العربية" data-language-local-name="Arapski" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-as mw-list-item"><a href="https://as.wikipedia.org/wiki/%E0%A6%A7%E0%A6%A8%E0%A7%81%E0%A6%B7%E0%A7%8D%E0%A6%9F%E0%A6%82%E0%A6%95%E0%A6%BE%E0%A7%B0" title="ধনুষ্টংকাৰ — Asemijski" lang="as" hreflang="as" data-title="ধনুষ্টংকাৰ" data-language-autonym="অসমীয়া" data-language-local-name="Asemijski" class="interlanguage-link-target"><span>অসমীয়া</span></a></li><li class="interlanguage-link interwiki-ast mw-list-item"><a href="https://ast.wikipedia.org/wiki/T%C3%A9tanu" title="Tétanu — Asturijski" lang="ast" hreflang="ast" data-title="Tétanu" data-language-autonym="Asturianu" data-language-local-name="Asturijski" class="interlanguage-link-target"><span>Asturianu</span></a></li><li class="interlanguage-link interwiki-az mw-list-item"><a href="https://az.wikipedia.org/wiki/Tetanus" title="Tetanus — Azerbejdžanski" lang="az" hreflang="az" data-title="Tetanus" data-language-autonym="Azərbaycanca" data-language-local-name="Azerbejdžanski" class="interlanguage-link-target"><span>Azərbaycanca</span></a></li><li class="interlanguage-link interwiki-azb mw-list-item"><a href="https://azb.wikipedia.org/wiki/%DA%A9%D9%88%D8%B2%D8%A7%D8%B2" title="کوزاز — South Azerbaijani" lang="azb" hreflang="azb" data-title="کوزاز" data-language-autonym="تۆرکجه" data-language-local-name="South Azerbaijani" class="interlanguage-link-target"><span>تۆرکجه</span></a></li><li class="interlanguage-link interwiki-bcl mw-list-item"><a href="https://bcl.wikipedia.org/wiki/Tetanus" title="Tetanus — Central Bikol" lang="bcl" hreflang="bcl" data-title="Tetanus" data-language-autonym="Bikol Central" data-language-local-name="Central Bikol" class="interlanguage-link-target"><span>Bikol Central</span></a></li><li class="interlanguage-link interwiki-be mw-list-item"><a href="https://be.wikipedia.org/wiki/%D0%A1%D0%BB%D1%83%D0%BF%D0%BD%D1%8F%D0%BA" title="Слупняк — Beloruski" lang="be" hreflang="be" data-title="Слупняк" data-language-autonym="Беларуская" data-language-local-name="Beloruski" class="interlanguage-link-target"><span>Беларуская</span></a></li><li class="interlanguage-link interwiki-be-x-old mw-list-item"><a href="https://be-tarask.wikipedia.org/wiki/%D0%A1%D0%BB%D1%83%D0%BF%D0%BD%D1%8F%D0%BA" title="Слупняк — Belarusian (Taraškievica orthography)" lang="be-tarask" hreflang="be-tarask" data-title="Слупняк" data-language-autonym="Беларуская (тарашкевіца)" data-language-local-name="Belarusian (Taraškievica orthography)" class="interlanguage-link-target"><span>Беларуская (тарашкевіца)</span></a></li><li class="interlanguage-link interwiki-bg mw-list-item"><a href="https://bg.wikipedia.org/wiki/%D0%A2%D0%B5%D1%82%D0%B0%D0%BD%D1%83%D1%81" title="Тетанус — Bugarski" lang="bg" hreflang="bg" data-title="Тетанус" data-language-autonym="Български" data-language-local-name="Bugarski" class="interlanguage-link-target"><span>Български</span></a></li><li class="interlanguage-link interwiki-bn mw-list-item"><a href="https://bn.wikipedia.org/wiki/%E0%A6%A7%E0%A6%A8%E0%A7%81%E0%A6%B7%E0%A7%8D%E0%A6%9F%E0%A6%99%E0%A7%8D%E0%A6%95%E0%A6%BE%E0%A6%B0" title="ধনুষ্টঙ্কার — Bengalski" lang="bn" hreflang="bn" data-title="ধনুষ্টঙ্কার" data-language-autonym="বাংলা" data-language-local-name="Bengalski" class="interlanguage-link-target"><span>বাংলা</span></a></li><li class="interlanguage-link interwiki-bo mw-list-item"><a href="https://bo.wikipedia.org/wiki/%E0%BD%A2%E0%BE%A9%E0%BC%8B%E0%BD%A0%E0%BD%81%E0%BD%B4%E0%BD%98%E0%BC%8B%E0%BD%93%E0%BD%91%E0%BC%8D" title="རྩ་འཁུམ་ནད། — Tibetanski" lang="bo" hreflang="bo" data-title="རྩ་འཁུམ་ནད།" data-language-autonym="བོད་ཡིག" data-language-local-name="Tibetanski" class="interlanguage-link-target"><span>བོད་ཡིག</span></a></li><li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/Tetanus" title="Tetanus — Bosanski" lang="bs" hreflang="bs" data-title="Tetanus" data-language-autonym="Bosanski" data-language-local-name="Bosanski" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/T%C3%A8tanus" title="Tètanus — Katalonski" lang="ca" hreflang="ca" data-title="Tètanus" data-language-autonym="Català" data-language-local-name="Katalonski" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-ckb mw-list-item"><a href="https://ckb.wikipedia.org/wiki/%D8%AF%DB%95%D8%B1%D8%AF%DB%95%DA%A9%DB%86%D9%BE%D8%A7%D9%86" title="دەردەکۆپان — centralnokurdski" lang="ckb" hreflang="ckb" data-title="دەردەکۆپان" data-language-autonym="کوردی" data-language-local-name="centralnokurdski" class="interlanguage-link-target"><span>کوردی</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Tetanus" title="Tetanus — Češki" lang="cs" hreflang="cs" data-title="Tetanus" data-language-autonym="Čeština" data-language-local-name="Češki" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-cy mw-list-item"><a href="https://cy.wikipedia.org/wiki/Tetanws" title="Tetanws — Velški" lang="cy" hreflang="cy" data-title="Tetanws" data-language-autonym="Cymraeg" data-language-local-name="Velški" class="interlanguage-link-target"><span>Cymraeg</span></a></li><li class="interlanguage-link interwiki-da mw-list-item"><a href="https://da.wikipedia.org/wiki/Stivkrampe" title="Stivkrampe — Danski" lang="da" hreflang="da" data-title="Stivkrampe" data-language-autonym="Dansk" data-language-local-name="Danski" class="interlanguage-link-target"><span>Dansk</span></a></li><li class="interlanguage-link interwiki-dag mw-list-item"><a href="https://dag.wikipedia.org/wiki/Daridari" title="Daridari — Dagbani" lang="dag" hreflang="dag" data-title="Daridari" data-language-autonym="Dagbanli" data-language-local-name="Dagbani" class="interlanguage-link-target"><span>Dagbanli</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Tetanus" title="Tetanus — Nemački" lang="de" hreflang="de" data-title="Tetanus" data-language-autonym="Deutsch" data-language-local-name="Nemački" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-dv mw-list-item"><a href="https://dv.wikipedia.org/wiki/%DE%87%DE%A8%DE%8B%DE%A8%DE%8A%DE%AA%DE%81%DE%A6%DE%81%DE%B0%DE%8B%DE%A6%DE%89%DE%A7_%DE%84%DE%A6%DE%8D%DE%A8" title="އިދިފުށަށްދަމާ ބަލި — Divehijski" lang="dv" hreflang="dv" data-title="އިދިފުށަށްދަމާ ބަލި" data-language-autonym="ދިވެހިބަސް" data-language-local-name="Divehijski" class="interlanguage-link-target"><span>ދިވެހިބަސް</span></a></li><li class="interlanguage-link interwiki-el mw-list-item"><a href="https://el.wikipedia.org/wiki/%CE%A4%CE%AD%CF%84%CE%B1%CE%BD%CE%BF%CF%82" title="Τέτανος — Grčki" lang="el" hreflang="el" data-title="Τέτανος" data-language-autonym="Ελληνικά" data-language-local-name="Grčki" class="interlanguage-link-target"><span>Ελληνικά</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Tetanus" title="Tetanus — Engleski" lang="en" hreflang="en" data-title="Tetanus" data-language-autonym="English" data-language-local-name="Engleski" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-eo mw-list-item"><a href="https://eo.wikipedia.org/wiki/Tetanoso" title="Tetanoso — Esperanto" lang="eo" hreflang="eo" data-title="Tetanoso" data-language-autonym="Esperanto" data-language-local-name="Esperanto" class="interlanguage-link-target"><span>Esperanto</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/T%C3%A9tanos" title="Tétanos — Španski" lang="es" hreflang="es" data-title="Tétanos" data-language-autonym="Español" data-language-local-name="Španski" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-et mw-list-item"><a href="https://et.wikipedia.org/wiki/Teetanus" title="Teetanus — Estonski" lang="et" hreflang="et" data-title="Teetanus" data-language-autonym="Eesti" data-language-local-name="Estonski" class="interlanguage-link-target"><span>Eesti</span></a></li><li class="interlanguage-link interwiki-eu mw-list-item"><a href="https://eu.wikipedia.org/wiki/Tetanos" title="Tetanos — Baskijski" lang="eu" hreflang="eu" data-title="Tetanos" data-language-autonym="Euskara" data-language-local-name="Baskijski" class="interlanguage-link-target"><span>Euskara</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%DA%A9%D8%B2%D8%A7%D8%B2" title="کزاز — Persijski" lang="fa" hreflang="fa" data-title="کزاز" data-language-autonym="فارسی" data-language-local-name="Persijski" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/J%C3%A4ykk%C3%A4kouristus" title="Jäykkäkouristus — Finski" lang="fi" hreflang="fi" data-title="Jäykkäkouristus" data-language-autonym="Suomi" data-language-local-name="Finski" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/T%C3%A9tanos" title="Tétanos — Francuski" lang="fr" hreflang="fr" data-title="Tétanos" data-language-autonym="Français" data-language-local-name="Francuski" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-ga mw-list-item"><a href="https://ga.wikipedia.org/wiki/Teiteanas" title="Teiteanas — Irski" lang="ga" hreflang="ga" data-title="Teiteanas" data-language-autonym="Gaeilge" data-language-local-name="Irski" class="interlanguage-link-target"><span>Gaeilge</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/T%C3%A9tano" title="Tétano — Galski" lang="gl" hreflang="gl" data-title="Tétano" data-language-autonym="Galego" data-language-local-name="Galski" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-gn mw-list-item"><a href="https://gn.wikipedia.org/wiki/T%C3%A9tano" title="Tétano — Gvarani" lang="gn" hreflang="gn" data-title="Tétano" data-language-autonym="Avañe'ẽ" data-language-local-name="Gvarani" class="interlanguage-link-target"><span>Avañe'ẽ</span></a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%98%D7%98%D7%A0%D7%95%D7%A1" title="טטנוס — Hebrejski" lang="he" hreflang="he" data-title="טטנוס" data-language-autonym="עברית" data-language-local-name="Hebrejski" class="interlanguage-link-target"><span>עברית</span></a></li><li class="interlanguage-link interwiki-hi mw-list-item"><a href="https://hi.wikipedia.org/wiki/%E0%A4%A7%E0%A4%A8%E0%A5%81%E0%A4%B8%E0%A5%8D%E0%A4%A4%E0%A4%AE%E0%A5%8D%E0%A4%AD" title="धनुस्तम्भ — Hindi" lang="hi" hreflang="hi" data-title="धनुस्तम्भ" data-language-autonym="हिन्दी" data-language-local-name="Hindi" class="interlanguage-link-target"><span>हिन्दी</span></a></li><li class="interlanguage-link interwiki-hr mw-list-item"><a href="https://hr.wikipedia.org/wiki/Tetanus" title="Tetanus — Hrvatski" lang="hr" hreflang="hr" data-title="Tetanus" data-language-autonym="Hrvatski" data-language-local-name="Hrvatski" class="interlanguage-link-target"><span>Hrvatski</span></a></li><li class="interlanguage-link interwiki-hu mw-list-item"><a href="https://hu.wikipedia.org/wiki/Tetanusz" title="Tetanusz — Mađarski" lang="hu" hreflang="hu" data-title="Tetanusz" data-language-autonym="Magyar" data-language-local-name="Mađarski" class="interlanguage-link-target"><span>Magyar</span></a></li><li class="interlanguage-link interwiki-hy mw-list-item"><a href="https://hy.wikipedia.org/wiki/%D5%93%D5%A1%D5%B5%D5%BF%D5%A1%D6%81%D5%B8%D6%82%D5%B4" title="Փայտացում — Jermenski" lang="hy" hreflang="hy" data-title="Փայտացում" data-language-autonym="Հայերեն" data-language-local-name="Jermenski" class="interlanguage-link-target"><span>Հայերեն</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Tetanus" title="Tetanus — Indonezijski" lang="id" hreflang="id" data-title="Tetanus" data-language-autonym="Bahasa Indonesia" data-language-local-name="Indonezijski" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-is mw-list-item"><a href="https://is.wikipedia.org/wiki/St%C3%ADfkrampi" title="Stífkrampi — Islandski" lang="is" hreflang="is" data-title="Stífkrampi" data-language-autonym="Íslenska" data-language-local-name="Islandski" class="interlanguage-link-target"><span>Íslenska</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Tetano" title="Tetano — Italijanski" lang="it" hreflang="it" data-title="Tetano" data-language-autonym="Italiano" data-language-local-name="Italijanski" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E7%A0%B4%E5%82%B7%E9%A2%A8" title="破傷風 — Japanski" lang="ja" hreflang="ja" data-title="破傷風" data-language-autonym="日本語" data-language-local-name="Japanski" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-jv mw-list-item"><a href="https://jv.wikipedia.org/wiki/T%C3%A9tanus" title="Tétanus — Javanski" lang="jv" hreflang="jv" data-title="Tétanus" data-language-autonym="Jawa" data-language-local-name="Javanski" class="interlanguage-link-target"><span>Jawa</span></a></li><li class="interlanguage-link interwiki-ka mw-list-item"><a href="https://ka.wikipedia.org/wiki/%E1%83%A2%E1%83%94%E1%83%A2%E1%83%90%E1%83%9C%E1%83%A3%E1%83%A1%E1%83%98" title="ტეტანუსი — Gruzijski" lang="ka" hreflang="ka" data-title="ტეტანუსი" data-language-autonym="ქართული" data-language-local-name="Gruzijski" class="interlanguage-link-target"><span>ქართული</span></a></li><li class="interlanguage-link interwiki-kk mw-list-item"><a href="https://kk.wikipedia.org/wiki/%D0%A1%D1%96%D1%80%D0%B5%D1%81%D0%BF%D0%B5" title="Сіреспе — Kozački" lang="kk" hreflang="kk" data-title="Сіреспе" data-language-autonym="Қазақша" data-language-local-name="Kozački" class="interlanguage-link-target"><span>Қазақша</span></a></li><li class="interlanguage-link interwiki-kn mw-list-item"><a href="https://kn.wikipedia.org/wiki/%E0%B2%A7%E0%B2%A8%E0%B3%81%E0%B2%B0%E0%B3%8D%E0%B2%B5%E0%B2%BE%E0%B2%A4" title="ಧನುರ್ವಾತ — Kanada" lang="kn" hreflang="kn" data-title="ಧನುರ್ವಾತ" data-language-autonym="ಕನ್ನಡ" data-language-local-name="Kanada" class="interlanguage-link-target"><span>ಕನ್ನಡ</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%ED%8C%8C%EC%83%81%ED%92%8D" title="파상풍 — Korejski" lang="ko" hreflang="ko" data-title="파상풍" data-language-autonym="한국어" data-language-local-name="Korejski" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-ku mw-list-item"><a href="https://ku.wikipedia.org/wiki/Derd%C3%AA_kopan" title="Derdê kopan — Kurdski" lang="ku" hreflang="ku" data-title="Derdê kopan" data-language-autonym="Kurdî" data-language-local-name="Kurdski" class="interlanguage-link-target"><span>Kurdî</span></a></li><li class="interlanguage-link interwiki-la mw-list-item"><a href="https://la.wikipedia.org/wiki/Tetanus" title="Tetanus — Latinski" lang="la" hreflang="la" data-title="Tetanus" data-language-autonym="Latina" data-language-local-name="Latinski" class="interlanguage-link-target"><span>Latina</span></a></li><li class="interlanguage-link interwiki-lg mw-list-item"><a href="https://lg.wikipedia.org/wiki/Okutana" title="Okutana — Ganda" lang="lg" hreflang="lg" data-title="Okutana" data-language-autonym="Luganda" data-language-local-name="Ganda" class="interlanguage-link-target"><span>Luganda</span></a></li><li class="interlanguage-link interwiki-lmo mw-list-item"><a href="https://lmo.wikipedia.org/wiki/Tetan" title="Tetan — lombardski" lang="lmo" hreflang="lmo" data-title="Tetan" data-language-autonym="Lombard" data-language-local-name="lombardski" class="interlanguage-link-target"><span>Lombard</span></a></li><li class="interlanguage-link interwiki-ln mw-list-item"><a href="https://ln.wikipedia.org/wiki/Tetan%C9%94%CC%81si" title="Tetanɔ́si — Lingala" lang="ln" hreflang="ln" data-title="Tetanɔ́si" data-language-autonym="Lingála" data-language-local-name="Lingala" class="interlanguage-link-target"><span>Lingála</span></a></li><li class="interlanguage-link interwiki-lt mw-list-item"><a href="https://lt.wikipedia.org/wiki/Stablig%C4%97" title="Stabligė — Litvanski" lang="lt" hreflang="lt" data-title="Stabligė" data-language-autonym="Lietuvių" data-language-local-name="Litvanski" class="interlanguage-link-target"><span>Lietuvių</span></a></li><li class="interlanguage-link interwiki-lv mw-list-item"><a href="https://lv.wikipedia.org/wiki/Stingumkrampji" title="Stingumkrampji — Letonski" lang="lv" hreflang="lv" data-title="Stingumkrampji" data-language-autonym="Latviešu" data-language-local-name="Letonski" class="interlanguage-link-target"><span>Latviešu</span></a></li><li class="interlanguage-link interwiki-mk mw-list-item"><a href="https://mk.wikipedia.org/wiki/%D0%A2%D0%B5%D1%82%D0%B0%D0%BD%D1%83%D1%81" title="Тетанус — Makedonski" lang="mk" hreflang="mk" data-title="Тетанус" data-language-autonym="Македонски" data-language-local-name="Makedonski" class="interlanguage-link-target"><span>Македонски</span></a></li><li class="interlanguage-link interwiki-ml mw-list-item"><a href="https://ml.wikipedia.org/wiki/%E0%B4%9F%E0%B5%86%E0%B4%B1%E0%B5%8D%E0%B4%B1%E0%B4%A8%E0%B4%B8%E0%B5%8D" title="ടെറ്റനസ് — Malajalam" lang="ml" hreflang="ml" data-title="ടെറ്റനസ്" data-language-autonym="മലയാളം" data-language-local-name="Malajalam" class="interlanguage-link-target"><span>മലയാളം</span></a></li><li class="interlanguage-link interwiki-mr mw-list-item"><a href="https://mr.wikipedia.org/wiki/%E0%A4%A7%E0%A4%A8%E0%A5%81%E0%A4%B0%E0%A5%8D%E0%A4%B5%E0%A4%BE%E0%A4%A4" title="धनुर्वात — Marati" lang="mr" hreflang="mr" data-title="धनुर्वात" data-language-autonym="मराठी" data-language-local-name="Marati" class="interlanguage-link-target"><span>मराठी</span></a></li><li class="interlanguage-link interwiki-ms mw-list-item"><a href="https://ms.wikipedia.org/wiki/Kancing_gigi" title="Kancing gigi — Malajski" lang="ms" hreflang="ms" data-title="Kancing gigi" data-language-autonym="Bahasa Melayu" data-language-local-name="Malajski" class="interlanguage-link-target"><span>Bahasa Melayu</span></a></li><li class="interlanguage-link interwiki-ne mw-list-item"><a href="https://ne.wikipedia.org/wiki/%E0%A4%A7%E0%A4%A8%E0%A5%81%E0%A4%B7%E0%A5%8D%E0%A4%9F%E0%A4%99%E0%A5%8D%E0%A4%95%E0%A4%BE%E0%A4%B0" title="धनुष्टङ्कार — Nepalski" lang="ne" hreflang="ne" data-title="धनुष्टङ्कार" data-language-autonym="नेपाली" data-language-local-name="Nepalski" class="interlanguage-link-target"><span>नेपाली</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Tetanus" title="Tetanus — Holandski" lang="nl" hreflang="nl" data-title="Tetanus" data-language-autonym="Nederlands" data-language-local-name="Holandski" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-no mw-list-item"><a href="https://no.wikipedia.org/wiki/Stivkrampe" title="Stivkrampe — Norveški bokmål" lang="nb" hreflang="nb" data-title="Stivkrampe" data-language-autonym="Norsk bokmål" data-language-local-name="Norveški bokmål" class="interlanguage-link-target"><span>Norsk bokmål</span></a></li><li class="interlanguage-link interwiki-oc mw-list-item"><a href="https://oc.wikipedia.org/wiki/Tetan%C3%B2s" title="Tetanòs — Provansalski" lang="oc" hreflang="oc" data-title="Tetanòs" data-language-autonym="Occitan" data-language-local-name="Provansalski" class="interlanguage-link-target"><span>Occitan</span></a></li><li class="interlanguage-link interwiki-or mw-list-item"><a href="https://or.wikipedia.org/wiki/%E0%AC%A7%E0%AC%A8%E0%AD%81%E0%AC%B7%E0%AD%8D%E0%AC%9F%E0%AC%99%E0%AD%8D%E0%AC%95%E0%AC%BE%E0%AC%B0" title="ଧନୁଷ୍ଟଙ୍କାର — Orijski" lang="or" hreflang="or" data-title="ଧନୁଷ୍ଟଙ୍କାର" data-language-autonym="ଓଡ଼ିଆ" data-language-local-name="Orijski" class="interlanguage-link-target"><span>ଓଡ଼ିଆ</span></a></li><li class="interlanguage-link interwiki-pa mw-list-item"><a href="https://pa.wikipedia.org/wiki/%E0%A8%A7%E0%A9%81%E0%A8%A3%E0%A8%96%E0%A8%B5%E0%A8%BE" title="ਧੁਣਖਵਾ — Pandžabski" lang="pa" hreflang="pa" data-title="ਧੁਣਖਵਾ" data-language-autonym="ਪੰਜਾਬੀ" data-language-local-name="Pandžabski" class="interlanguage-link-target"><span>ਪੰਜਾਬੀ</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/T%C4%99%C5%BCec" title="Tężec — Poljski" lang="pl" hreflang="pl" data-title="Tężec" data-language-autonym="Polski" data-language-local-name="Poljski" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/T%C3%A9tano" title="Tétano — Portugalski" lang="pt" hreflang="pt" data-title="Tétano" data-language-autonym="Português" data-language-local-name="Portugalski" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Tetanos" title="Tetanos — Rumunski" lang="ro" hreflang="ro" data-title="Tetanos" data-language-autonym="Română" data-language-local-name="Rumunski" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%A1%D1%82%D0%BE%D0%BB%D0%B1%D0%BD%D1%8F%D0%BA" title="Столбняк — Ruski" lang="ru" hreflang="ru" data-title="Столбняк" data-language-autonym="Русский" data-language-local-name="Ruski" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-se mw-list-item"><a href="https://se.wikipedia.org/wiki/Doa%C5%8Bgegeas%C3%A1hat" title="Doaŋgegeasáhat — Severni sami" lang="se" hreflang="se" data-title="Doaŋgegeasáhat" data-language-autonym="Davvisámegiella" data-language-local-name="Severni sami" class="interlanguage-link-target"><span>Davvisámegiella</span></a></li><li class="interlanguage-link interwiki-simple mw-list-item"><a href="https://simple.wikipedia.org/wiki/Tetanus" title="Tetanus — Simple English" lang="en-simple" hreflang="en-simple" data-title="Tetanus" data-language-autonym="Simple English" data-language-local-name="Simple English" class="interlanguage-link-target"><span>Simple English</span></a></li><li class="interlanguage-link interwiki-sk mw-list-item"><a href="https://sk.wikipedia.org/wiki/Tetanus" title="Tetanus — Slovački" lang="sk" hreflang="sk" data-title="Tetanus" data-language-autonym="Slovenčina" data-language-local-name="Slovački" class="interlanguage-link-target"><span>Slovenčina</span></a></li><li class="interlanguage-link interwiki-sl mw-list-item"><a href="https://sl.wikipedia.org/wiki/Tetanus" title="Tetanus — Slovenački" lang="sl" hreflang="sl" data-title="Tetanus" data-language-autonym="Slovenščina" data-language-local-name="Slovenački" class="interlanguage-link-target"><span>Slovenščina</span></a></li><li class="interlanguage-link interwiki-sq mw-list-item"><a href="https://sq.wikipedia.org/wiki/Tetanosi" title="Tetanosi — Albanski" lang="sq" hreflang="sq" data-title="Tetanosi" data-language-autonym="Shqip" data-language-local-name="Albanski" class="interlanguage-link-target"><span>Shqip</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/%D0%A2%D0%B5%D1%82%D0%B0%D0%BD%D1%83%D1%81" title="Тетанус — Srpski" lang="sr" hreflang="sr" data-title="Тетанус" data-language-autonym="Српски / srpski" data-language-local-name="Srpski" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-su mw-list-item"><a href="https://su.wikipedia.org/wiki/T%C3%A9tanus" title="Tétanus — Sudanski" lang="su" hreflang="su" data-title="Tétanus" data-language-autonym="Sunda" data-language-local-name="Sudanski" class="interlanguage-link-target"><span>Sunda</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Stelkramp" title="Stelkramp — Švedski" lang="sv" hreflang="sv" data-title="Stelkramp" data-language-autonym="Svenska" data-language-local-name="Švedski" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-sw mw-list-item"><a href="https://sw.wikipedia.org/wiki/Pepopunda" title="Pepopunda — Svahili" lang="sw" hreflang="sw" data-title="Pepopunda" data-language-autonym="Kiswahili" data-language-local-name="Svahili" class="interlanguage-link-target"><span>Kiswahili</span></a></li><li class="interlanguage-link interwiki-ta mw-list-item"><a href="https://ta.wikipedia.org/wiki/%E0%AE%87%E0%AE%B0%E0%AE%A3%E0%AE%9C%E0%AE%A9%E0%AF%8D%E0%AE%A9%E0%AE%BF" title="இரணஜன்னி — Tamilski" lang="ta" hreflang="ta" data-title="இரணஜன்னி" data-language-autonym="தமிழ்" data-language-local-name="Tamilski" class="interlanguage-link-target"><span>தமிழ்</span></a></li><li class="interlanguage-link interwiki-te mw-list-item"><a href="https://te.wikipedia.org/wiki/%E0%B0%A7%E0%B0%A8%E0%B1%81%E0%B0%B0%E0%B1%8D%E0%B0%B5%E0%B0%BE%E0%B0%A4%E0%B0%AE%E0%B1%81" title="ధనుర్వాతము — Telugu" lang="te" hreflang="te" data-title="ధనుర్వాతము" data-language-autonym="తెలుగు" data-language-local-name="Telugu" class="interlanguage-link-target"><span>తెలుగు</span></a></li><li class="interlanguage-link interwiki-th mw-list-item"><a href="https://th.wikipedia.org/wiki/%E0%B8%9A%E0%B8%B2%E0%B8%94%E0%B8%97%E0%B8%B0%E0%B8%A2%E0%B8%B1%E0%B8%81" title="บาดทะยัก — Tajlandski" lang="th" hreflang="th" data-title="บาดทะยัก" data-language-autonym="ไทย" data-language-local-name="Tajlandski" class="interlanguage-link-target"><span>ไทย</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Tetanos" title="Tetanos — Turski" lang="tr" hreflang="tr" data-title="Tetanos" data-language-autonym="Türkçe" data-language-local-name="Turski" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%9F%D1%80%D0%B0%D0%B2%D0%B5%D1%86%D1%8C" title="Правець — Ukrajinski" lang="uk" hreflang="uk" data-title="Правець" data-language-autonym="Українська" data-language-local-name="Ukrajinski" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-ur mw-list-item"><a href="https://ur.wikipedia.org/wiki/%D8%AA%D8%B4%D9%86%D8%AC" title="تشنج — Urdu" lang="ur" hreflang="ur" data-title="تشنج" data-language-autonym="اردو" data-language-local-name="Urdu" class="interlanguage-link-target"><span>اردو</span></a></li><li class="interlanguage-link interwiki-uz mw-list-item"><a href="https://uz.wikipedia.org/wiki/Qoqshol" title="Qoqshol — Uzbečki" lang="uz" hreflang="uz" data-title="Qoqshol" data-language-autonym="Oʻzbekcha / ўзбекча" data-language-local-name="Uzbečki" class="interlanguage-link-target"><span>Oʻzbekcha / ўзбекча</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/U%E1%BB%91n_v%C3%A1n" title="Uốn ván — Vijetnamski" lang="vi" hreflang="vi" data-title="Uốn ván" data-language-autonym="Tiếng Việt" data-language-local-name="Vijetnamski" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li><li class="interlanguage-link interwiki-wa mw-list-item"><a href="https://wa.wikipedia.org/wiki/Tetanosse" title="Tetanosse — Valun" lang="wa" hreflang="wa" data-title="Tetanosse" data-language-autonym="Walon" data-language-local-name="Valun" class="interlanguage-link-target"><span>Walon</span></a></li><li class="interlanguage-link interwiki-war mw-list-item"><a href="https://war.wikipedia.org/wiki/Tetanus" title="Tetanus — Varej" lang="war" hreflang="war" data-title="Tetanus" data-language-autonym="Winaray" data-language-local-name="Varej" class="interlanguage-link-target"><span>Winaray</span></a></li><li class="interlanguage-link interwiki-wuu mw-list-item"><a href="https://wuu.wikipedia.org/wiki/%E7%A0%B4%E4%BC%A4%E9%A3%8E" title="破伤风 — Wu kineski" lang="wuu" hreflang="wuu" data-title="破伤风" data-language-autonym="吴语" data-language-local-name="Wu kineski" class="interlanguage-link-target"><span>吴语</span></a></li><li class="interlanguage-link interwiki-xmf mw-list-item"><a href="https://xmf.wikipedia.org/wiki/%E1%83%A2%E1%83%94%E1%83%A2%E1%83%90%E1%83%9C%E1%83%A3%E1%83%A1%E1%83%98" title="ტეტანუსი — Mingrelian" lang="xmf" hreflang="xmf" data-title="ტეტანუსი" data-language-autonym="მარგალური" data-language-local-name="Mingrelian" class="interlanguage-link-target"><span>მარგალური</span></a></li><li class="interlanguage-link interwiki-zea mw-list-item"><a href="https://zea.wikipedia.org/wiki/Tetanus" title="Tetanus — Zeelandic" lang="zea" hreflang="zea" data-title="Tetanus" data-language-autonym="Zeêuws" data-language-local-name="Zeelandic" class="interlanguage-link-target"><span>Zeêuws</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E7%A0%B4%E5%82%B7%E9%A2%A8" title="破傷風 — Kineski" lang="zh" hreflang="zh" data-title="破傷風" data-language-autonym="中文" data-language-local-name="Kineski" class="interlanguage-link-target"><span>中文</span></a></li><li class="interlanguage-link interwiki-zh-yue mw-list-item"><a href="https://zh-yue.wikipedia.org/wiki/%E7%A0%B4%E5%82%B7%E9%A2%A8" title="破傷風 — kantonski" lang="yue" hreflang="yue" data-title="破傷風" data-language-autonym="粵語" data-language-local-name="kantonski" class="interlanguage-link-target"><span>粵語</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q47790#sitelinks-wikipedia" title="Uredi međujezične poveznice" class="wbc-editpage">Uredi veze</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Imenski prostori"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet 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href="/wiki/Posebno:Povezane_izmjene/Tetanus" rel="nofollow" title="Prelistajte nedavne izmjene stranica koje su povezane s ovom [k]" accesskey="k"><span>Povezane izmjene</span></a></li><li id="t-specialpages" class="mw-list-item"><a href="/wiki/Posebno:Posebne_stranice" title="Pregledajte listu svih posebnih stranica [q]" accesskey="q"><span>Posebne stranice</span></a></li><li id="t-permalink" class="mw-list-item"><a href="/w/index.php?title=Tetanus&oldid=42178994" title="Nabavite trajnu vezu do ove verzije stranice"><span>Trajna veza</span></a></li><li id="t-info" class="mw-list-item"><a href="/w/index.php?title=Tetanus&action=info" title="Pronađite više informacija o ovoj stranici"><span>Podaci o stranici</span></a></li><li id="t-cite" class="mw-list-item"><a href="/w/index.php?title=Posebno:Citiraj&page=Tetanus&id=42178994&wpFormIdentifier=titleform" title="Saznajte kako da citirate ovu stranicu"><span>Citiraj stranicu</span></a></li><li id="t-urlshortener" class="mw-list-item"><a href="/w/index.php?title=Posebno:Skra%C4%87iva%C4%8D_adresa&url=https%3A%2F%2Fsh.wikipedia.org%2Fwiki%2FTetanus"><span>Skrati URL</span></a></li><li id="t-urlshortener-qrcode" class="mw-list-item"><a href="/w/index.php?title=Posebno:QrCode&url=https%3A%2F%2Fsh.wikipedia.org%2Fwiki%2FTetanus"><span>Preuzmi QR kod</span></a></li> </ul> </div> </div> <div id="p-coll-print_export" class="vector-menu mw-portlet mw-portlet-coll-print_export" lang="sh-Latn" dir="ltr"> <div class="vector-menu-heading"> Štampanje/izvoz </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="coll-create_a_book" class="mw-list-item"><a href="/w/index.php?title=Posebno:Kolekcija&bookcmd=book_creator&referer=Tetanus"><span>Napravi knjigu</span></a></li><li id="coll-download-as-rl" class="mw-list-item"><a href="/w/index.php?title=Posebno:DownloadAsPdf&page=Tetanus&action=show-download-screen"><span>Preuzmi kao PDF</span></a></li><li id="t-print" class="mw-list-item"><a href="/w/index.php?title=Tetanus&printable=yes" title="Odštampajte ovu stranicu [p]" accesskey="p"><span>Odštampaj</span></a></li> </ul> </div> </div> <div id="p-wikibase-otherprojects" class="vector-menu mw-portlet mw-portlet-wikibase-otherprojects" lang="sh-Latn" dir="ltr"> <div class="vector-menu-heading"> Na drugim projektima </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="wb-otherproject-link wb-otherproject-commons mw-list-item"><a href="https://commons.wikimedia.org/wiki/Tetanus" hreflang="en"><span>Wikimedia Commons</span></a></li><li id="t-wikibase" class="wb-otherproject-link wb-otherproject-wikibase-dataitem mw-list-item"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q47790" title="Pogledajte povezanu stavku u skladištu podataka [g]" accesskey="g"><span>Stavka na Wikipodacima</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> </div> </div> </div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="Pomagala"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="Izgled"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Izgled</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">premjesti na bočnu traku</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">sakrij</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">Izvor: Wikipedija</div> </div> <div id="contentSub" lang="sh-Latn" dir="ltr"><div id="mw-content-subtitle" lang="sh-Latn" dir="ltr"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="sh-Latn" dir="ltr"><p><b>Tetanus</b> je akutno oboljenje izazvano <a href="/wiki/Toksin" class="mw-redirect" title="Toksin">toksinima</a> bakterije <a href="/wiki/Klostridije" class="mw-redirect" title="Klostridije">klostridujum tetani</a> (<a href="/wiki/Latinski_jezik" title="Latinski jezik">lat</a>. <i>Clostridium tetani</i>). Klostridija tetanusa proizvodi jak neurotoksin, <a href="/wiki/Tetanospazmin" title="Tetanospazmin">tetanospazmin</a>, koji se vezuje za <a href="/wiki/Receptor" class="mw-redirect" title="Receptor">receptore</a> nervnih ćelija i sprečava prenošenje inhibitornih signala iz <a href="/wiki/Mali_mozak" title="Mali mozak">malog mozga</a> na mišićne motorne neurone. Kao posledica se javlja pojačana mišićna aktivnost u vidu <a href="/wiki/Gr%C4%8D" title="Grč">grčeva</a> i povećan <a href="/w/index.php?title=Mi%C5%A1i%C4%87ni_tonus&action=edit&redlink=1" class="new" title="Mišićni tonus (stranica ne postoji)">mišićni tonus</a>. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Uzročnik"><span id="Uzro.C4.8Dnik"></span>Uzročnik</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Tetanus&veaction=edit&section=1" title="Uredi odjeljak Uzročnik" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Tetanus&action=edit&section=1" title="Uredi kôd odjeljka Uzročnik"><span>uredi kod</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Tetanus je izazvan tetanospazminom, toksinom bakterije klostridijum tetani. To je relativno krupna, gram pozitivna, bakterija veličine 3-8 μm, štapićastog oblika. Klostridije su anaerobne bakterije i nalaze se svuda, posebno u zemlji i crevu čoveka. U nepovoljnim uslovima grade <a href="/wiki/Spore" title="Spore">spore</a>. Klostridija tetanusa poseduje treplje pomoću kojih se kreće. </p><p><a href="/wiki/Toksin" class="mw-redirect" title="Toksin">Toksin</a> tetanusa pripada grupi <a href="/w/index.php?title=AB_toksin&action=edit&redlink=1" class="new" title="AB toksin (stranica ne postoji)">AB toksina</a>. Sastoji se iz dve podjedinice A i B povezane disulfidnim mostom. Veća podjedinica B (<a href="/wiki/Engleski_jezik" title="Engleski jezik">engl.</a> <i><span lang="en">binding</span></i>vezujuća) se vezuje za receptore nervnih ćelija. Manja podjedinica A, je aktivna komponenta i to je <a href="/wiki/Enzim" title="Enzim">enzim</a> iz grupe <a href="/wiki/Cink" title="Cink">cink</a>-<a href="/w/index.php?title=Metaloproteinaza&action=edit&redlink=1" class="new" title="Metaloproteinaza (stranica ne postoji)">metaloproteinaza</a>. Ova komponenta razlaže proteine koji učestvuju u procesu <a href="/wiki/Sinapsa" title="Sinapsa">sekrecije inhibitornih neurotransmitera</a> u prednjim rogovima <a href="/wiki/Ki%C4%8Dmena_mo%C5%BEdina" title="Kičmena moždina">kičmene moždine</a>. Kao posledica javlja se povećan <a href="/w/index.php?title=Mi%C5%A1i%C4%87ni_tonus&action=edit&redlink=1" class="new" title="Mišićni tonus (stranica ne postoji)">mišićni tonus</a> i aktivnost u vidu <a href="/wiki/Gr%C4%8D" title="Grč">grčeva</a> mišića. </p> <div class="mw-heading mw-heading2"><h2 id="Patogeneza_i_simptomi">Patogeneza i simptomi</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Tetanus&veaction=edit&section=2" title="Uredi odjeljak Patogeneza i simptomi" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Tetanus&action=edit&section=2" title="Uredi kôd odjeljka Patogeneza i simptomi"><span>uredi kod</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Nakon povrede dolazi do naseljavana rane raznim bakterijama, između kojih je i klostridija tetanusa, koja je široko rasprostranjena. Ukoliko u rani postoje anaerobni uslovi dolazi do razmnožavanja ove bakterije i proizvodnje toksina, tetanospazmina. Tetanospazmin dolazi putem nervnih vlakana ili krvi do prednjih rogova kičmene moždine gde ispoljava svoje dejstvo. Ovaj toksin blokira oslobađanje inhibitornih <a href="/wiki/Neurotransmiter" title="Neurotransmiter">neurotransmitera</a>: <a href="/wiki/GABA" class="mw-redirect" title="GABA">GABA</a> i <a href="/wiki/Glicin" title="Glicin">glicina</a>, što za posledicu ima povećanje mišićnog tonusa i nekontrlisane mišićne kontrakcije u vidu grčeva izazvanih optičim i akustičkim dražima. Simptomi se najpre javljaju na mišiću <a href="/w/index.php?title=Maseter&action=edit&redlink=1" class="new" title="Maseter (stranica ne postoji)">maseteru</a> koji učestvuje u žvakanju u vidu povišenog tonusa i grča ovog mišića-trizmus. Zatim sledi ukočenost vrata i mišića leđa. Usled grča mišića lica javlja se sardonični (iskeženi) osmeh (<a href="/wiki/Latinski_jezik" title="Latinski jezik">lat</a>. <i>risus sardonicus</i>). Postoje i problemi sa gutanjem, ili sa disanjem ukoliko dođe do grča mišića <a href="/wiki/Grkljan" title="Grkljan">grkljana</a> ili <a href="/wiki/Dijafragma" class="mw-redirect" title="Dijafragma">dijafragme</a>. Na kraju dolazi do toničnih kontrakcije celokupne muskulature trupa-<a href="/w/index.php?title=Opistotonus&action=edit&redlink=1" class="new" title="Opistotonus (stranica ne postoji)">opistotonus</a>. Usled siline mišićnih kontrakcija može doći do istezanja i pucanja <a href="/w/index.php?title=Tetiva&action=edit&redlink=1" class="new" title="Tetiva (stranica ne postoji)">tetiva</a>, preloma kostiju... Telesna temperatura obolelih je takođe povišena, krvni pritisak može biti povišen i mogu se javiti poremećaji rada srca. Svest je očuvana. </p><p>Bolest se dijagnostikfikuje na osnovu kliničke slike, pronalaženja toksina putem PCR-a (jez-en|PCR) ili njegovim testiranjem na životinjama (npr. mišu). U terapiji je važna primena antitoksina, higijena rane, <a href="/w/index.php?title=Mi%C5%A1i%C4%87ni_relaksansi&action=edit&redlink=1" class="new" title="Mišićni relaksansi (stranica ne postoji)">mišićnih relaksanasa</a> itd. </p><p>Zahvaljujući vakcinaciji (<a href="/wiki/Difterija" title="Difterija">difterija</a>-<a href="/w/index.php?title=Pertusis&action=edit&redlink=1" class="new" title="Pertusis (stranica ne postoji)">pertusis</a>-tetanus <a href="/w/index.php?title=DTP&action=edit&redlink=1" class="new" title="DTP (stranica ne postoji)">DTP</a>) bolest je postala ređa. Ukoliko dođe do težih povreda 5 i više godina nakon vakcinacije, potrebno je primiti osvežavajuću dozu vakcine. </p> <div class="mw-heading mw-heading2"><h2 id="Povezano">Povezano</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Tetanus&veaction=edit&section=3" title="Uredi odjeljak Povezano" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Tetanus&action=edit&section=3" title="Uredi kôd odjeljka Povezano"><span>uredi kod</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/GABA" class="mw-redirect" title="GABA">GABA</a></li> <li><a href="/wiki/Glicin" title="Glicin">Glicin</a></li> <li><a href="/wiki/Gr%C4%8D" title="Grč">Grč</a></li> <li><a href="/w/index.php?title=Mi%C5%A1i%C4%87ni_tonus&action=edit&redlink=1" class="new" title="Mišićni tonus (stranica ne postoji)">Mišićni tonus</a></li> <li><a href="/w/index.php?title=DTP&action=edit&redlink=1" class="new" title="DTP (stranica ne postoji)">DTP</a></li> <li><a href="/wiki/Neurotransmiteri" class="mw-redirect" title="Neurotransmiteri">Neurotransmiteri</a></li> <li><a href="/wiki/Toksini" class="mw-redirect" title="Toksini">Toksini</a></li> <li><a href="/wiki/Klostridije" class="mw-redirect" title="Klostridije">Klostridije</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="Literatura">Literatura</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Tetanus&veaction=edit&section=4" title="Uredi odjeljak Literatura" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Tetanus&action=edit&section=4" title="Uredi kôd odjeljka Literatura"><span>uredi kod</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="infobox sisterproject" style="width: 300px"> <div style="float: left;"><figure class="mw-halign-none" typeof="mw:File"><a href="https://commons.wikimedia.org/wiki/Category:Tetanus" title="commons:Category:Tetanus"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/15px-Commons-logo.svg.png" decoding="async" width="15" height="20" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/23px-Commons-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/30px-Commons-logo.svg.png 2x" data-file-width="1024" data-file-height="1376" /></a><figcaption></figcaption></figure></div> <div style="margin-left: 20px;"><i><b><a href="https://commons.wikimedia.org/wiki/Category:Tetanus" class="extiw" title="commons:Category:Tetanus">Tetanus</a></b></i> na <a href="https://commons.wikimedia.org/wiki/Glavna_stranica_-_%D0%93%D0%BB%D0%B0%D0%B2%D0%BD%D0%B0_%D1%81%D1%82%D1%80%D0%B0%D0%BD%D0%B8%D1%86%D0%B0" class="extiw" title="commons:Glavna stranica - Главна страница">Wikimedijinoj ostavi</a> </div> </div> <ul><li>Fritz H. Keyser, Kurt A. Bienz <i>Medizinische Mikrobiologie</i> Thieme <a href="/wiki/ISBN" title="ISBN">ISBN</a> <a href="/wiki/Posebno:Tra%C5%BEi_ISBN/978-3-13-444810-8" title="Posebno:Traži ISBN/978-3-13-444810-8">978-3-13-444810-8</a></li></ul>    </div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?type=1x1&useformat=desktop" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="" lang="sh-Latn" dir="ltr">Izvor: <a dir="ltr" href="https://sh.wikipedia.org/w/index.php?title=Tetanus&oldid=42178994">https://sh.wikipedia.org/w/index.php?title=Tetanus&oldid=42178994</a></div></div> <div id="catlinks" class="catlinks" data-mw="interface"><div id="mw-normal-catlinks" class="mw-normal-catlinks"><a href="/wiki/Posebno:Kategorije" title="Posebno:Kategorije">Kategorije</a>: <ul><li><a href="/wiki/Kategorija:Infektivne_bolesti" title="Kategorija:Infektivne bolesti">Infektivne bolesti</a></li><li><a href="/wiki/Kategorija:Neurologija" title="Kategorija:Neurologija">Neurologija</a></li></ul></div></div> </div> </main> </div> <div class="mw-footer-container"> <footer id="footer" class="mw-footer" lang="sh-Latn" dir="ltr"> <ul id="footer-info"> <li id="footer-info-lastmod"> Ova stranica je posljednji put izmijenjena 18. augusta 2024. u 07:47.</li> <li id="footer-info-copyright">Tekst je dostupan pod licencom <a rel="nofollow" class="external text" href="https://creativecommons.org/licenses/by-sa/4.0/deed.en">Creative Commons Attribution-ShareAlike</a>; mogu se primijeniti i dodatni uslovi. 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