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Search results for: sensitivity analysis
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28884</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: sensitivity analysis</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28674</span> Chemical Fingerprinting of Complex Samples With the Aid of Parallel Outlet Flow Chromatography</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Xavier%20A.%20Conlan">Xavier A. Conlan </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Speed of analysis is a significant limitation to current high-performance liquid chromatography/mass spectrometry (HPLC/MS) and ultra-high-pressure liquid chromatography (UHPLC)/MS systems both of which are used in many forensic investigations. The flow rate limitations of MS detection require a compromise in the chromatographic flow rate, which in turn reduces throughput, and when using modern columns, a reduction in separation efficiency. Commonly, this restriction is combated through the post-column splitting of flow prior to entry into the mass spectrometer. However, this results in a loss of sensitivity and a loss in efficiency due to the post-extra column dead volume. A new chromatographic column format known as 'parallel segmented flow' involves the splitting of eluent flow within the column outlet end fitting, and in this study we present its application in order to interrogate the provenience of methamphetamine samples with mass spectrometry detection. Using parallel segmented flow, column flow rates as high as 3 mL/min were employed in the analysis of amino acids without post-column splitting to the mass spectrometer. Furthermore, when parallel segmented flow chromatography columns were employed, the sensitivity was more than twice that of conventional systems with post-column splitting when the same volume of mobile phase was passed through the detector. These finding suggest that this type of column technology will particularly enhance the capabilities of modern LC/MS enabling both high-throughput and sensitive mass spectral detection. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=chromatography" title="chromatography">chromatography</a>, <a href="https://publications.waset.org/abstracts/search?q=mass%20spectrometry%20methamphetamine" title=" mass spectrometry methamphetamine"> mass spectrometry methamphetamine</a>, <a href="https://publications.waset.org/abstracts/search?q=parallel%20segmented%20outlet%20flow%20column" title=" parallel segmented outlet flow column"> parallel segmented outlet flow column</a>, <a href="https://publications.waset.org/abstracts/search?q=forensic%20sciences" title=" forensic sciences"> forensic sciences</a> </p> <a href="https://publications.waset.org/abstracts/23798/chemical-fingerprinting-of-complex-samples-with-the-aid-of-parallel-outlet-flow-chromatography" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/23798.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">490</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28673</span> Non-Linear Assessment of Chromatographic Lipophilicity of Selected Steroid Derivatives</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Milica%20Karad%C5%BEi%C4%87">Milica Karadžić</a>, <a href="https://publications.waset.org/abstracts/search?q=Lidija%20Jevri%C4%87"> Lidija Jevrić</a>, <a href="https://publications.waset.org/abstracts/search?q=Sanja%20Podunavac-Kuzmanovi%C4%87"> Sanja Podunavac-Kuzmanović</a>, <a href="https://publications.waset.org/abstracts/search?q=Strahinja%20Kova%C4%8Devi%C4%87"> Strahinja Kovačević</a>, <a href="https://publications.waset.org/abstracts/search?q=Anamarija%20Mandi%C4%87"> Anamarija Mandić</a>, <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20Oklje%C5%A1a"> Aleksandar Oklješa</a>, <a href="https://publications.waset.org/abstracts/search?q=Andrea%20Nikoli%C4%87"> Andrea Nikolić</a>, <a href="https://publications.waset.org/abstracts/search?q=Marija%20Saka%C4%8D"> Marija Sakač</a>, <a href="https://publications.waset.org/abstracts/search?q=Katarina%20Penov%20Ga%C5%A1i"> Katarina Penov Gaši</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Using chemometric approach, the relationships between the chromatographic lipophilicity and in silico molecular descriptors for twenty-nine selected steroid derivatives were studied. The chromatographic lipophilicity was predicted using artificial neural networks (ANNs) method. The most important in silico molecular descriptors were selected applying stepwise selection (SS) paired with partial least squares (PLS) method. Molecular descriptors with satisfactory variable importance in projection (VIP) values were selected for ANN modeling. The usefulness of generated models was confirmed by detailed statistical validation. High agreement between experimental and predicted values indicated that obtained models have good quality and high predictive ability. Global sensitivity analysis (GSA) confirmed the importance of each molecular descriptor used as an input variable. High-quality networks indicate a strong non-linear relationship between chromatographic lipophilicity and used in silico molecular descriptors. Applying selected molecular descriptors and generated ANNs the good prediction of chromatographic lipophilicity of the studied steroid derivatives can be obtained. This article is based upon work from COST Actions (CM1306 and CA15222), supported by COST (European Cooperation and Science and Technology). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=artificial%20neural%20networks" title="artificial neural networks">artificial neural networks</a>, <a href="https://publications.waset.org/abstracts/search?q=chemometrics" title=" chemometrics"> chemometrics</a>, <a href="https://publications.waset.org/abstracts/search?q=global%20sensitivity%20analysis" title=" global sensitivity analysis"> global sensitivity analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=liquid%20chromatography" title=" liquid chromatography"> liquid chromatography</a>, <a href="https://publications.waset.org/abstracts/search?q=steroids" title=" steroids"> steroids</a> </p> <a href="https://publications.waset.org/abstracts/60203/non-linear-assessment-of-chromatographic-lipophilicity-of-selected-steroid-derivatives" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/60203.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">345</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28672</span> The MoEDAL-MAPP* Experiment - Expanding the Discovery Horizon of the Large Hadron Collider</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=James%20Pinfold">James Pinfold</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The MoEDAL (Monopole and Exotics Detector at the LHC) experiment deployed at IP8 on the Large Hadron Collider ring was the first dedicated search experiment to take data at the Large Hadron Collider (LHC) in 2010. It was designed to search for Highly Ionizing Particle (HIP) avatars of new physics such as magnetic monopoles, dyons, Q-balls, multiply charged particles, massive, slowly moving charged particles and long-lived massive charge SUSY particles. We shall report on our search at LHC’s Run-2 for Magnetic monopoles and dyons produced in p-p and photon-fusion. In more detail, we will report our most recent result in this arena: the search for magnetic monopoles via the Schwinger Mechanism in Pb-Pb collisions. The MoEDAL detector, originally the first dedicated search detector at the LHC, is being reinstalled for LHC’s Run-3 to continue the search for electrically and magnetically charged HIPs with enhanced instantaneous luminosity, detector efficiency and a factor of ten lower thresholds for HIPs. As part of this effort, we will search for massive l long-lived, singly and multiply charged particles from various scenarios for which MoEDAL has a competitive sensitivity. An upgrade to MoEDAL, the MoEDAL Apparatus for Penetrating Particles (MAPP), is now the LHC’s newest detector. The MAPP detector, positioned in UA83, expands the physics reach of MoEDAL to include sensitivity to feebly-charged particles with charge, or effective charge, as low as 10-3 e (where e is the electron charge). Also, In conjunction with MoEDAL’s trapping detector, the MAPP detector gives us a unique sensitivity to extremely long-lived charged particles. MAPP also has some sensitivity to long-lived neutral particles. The addition of an Outrigger detector for MAPP-1 to increase its acceptance for more massive milli-charged particles is currently in the Technical Proposal stage. Additionally, we will briefly report on the plans for the MAPP-2 upgrade to the MoEDAL-MAPP experiment for the High Luminosity LHC (HL-LHC). This experiment phase is designed to maximize MoEDAL-MAPP’s sensitivity to very long-lived neutral messengers of physics beyond the Standard Model. We envisage this detector being deployed in the UGC1 gallery near IP8. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=LHC" title="LHC">LHC</a>, <a href="https://publications.waset.org/abstracts/search?q=beyond%20the%20standard%20model" title=" beyond the standard model"> beyond the standard model</a>, <a href="https://publications.waset.org/abstracts/search?q=dedicated%20search%20experiment" title=" dedicated search experiment"> dedicated search experiment</a>, <a href="https://publications.waset.org/abstracts/search?q=highly%20ionizing%20particles" title=" highly ionizing particles"> highly ionizing particles</a>, <a href="https://publications.waset.org/abstracts/search?q=long-lived%20particles" title=" long-lived particles"> long-lived particles</a>, <a href="https://publications.waset.org/abstracts/search?q=milli-charged%20particles" title=" milli-charged particles"> milli-charged particles</a> </p> <a href="https://publications.waset.org/abstracts/167524/the-moedal-mapp-experiment-expanding-the-discovery-horizon-of-the-large-hadron-collider" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/167524.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">68</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28671</span> Functional Poly(Hedral Oligomeric Silsesquioxane) Nano-Spacer to Boost Quantum Resistive Vapour Sensors’ Sensitivity and Selectivity</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jean-Francois%20Feller">Jean-Francois Feller</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The analysis of the volatolome emitted by the human body with a sensor array (e-nose) is a method for clinical applications full of promises to make an olfactive fingerprint characteristic of people's health state. But the amount of volatile organic compounds (VOC) to detect, being in the range of parts per billion (ppb), and their diversity (several hundred) justifies developing ever more sensitive and selective vapor sensors to improve the discrimination ability of the e-nose, is still of interest. Quantum resistive vapour sensors (vQRS) made with nanostructured conductive polymer nanocomposite transducers have shown a great versatility in both their fabrication and operation to detect volatiles of interest such as cancer biomarkers. However, it has been shown that their chemo-resistive response was highly dependent on the quality of the inter-particular junctions in the percolated architecture. The present work investigates the effectiveness of poly(hedral oligomeric silsesquioxane) acting as a nanospacer to amplify the disconnectability of the conducting network and thus maximize the vQRS's sensitivity to VOC. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=volatolome" title="volatolome">volatolome</a>, <a href="https://publications.waset.org/abstracts/search?q=quantum%20resistive%20vapour%20sensor" title=" quantum resistive vapour sensor"> quantum resistive vapour sensor</a>, <a href="https://publications.waset.org/abstracts/search?q=nanostructured%20conductive%20polymer%20nanocomposites" title=" nanostructured conductive polymer nanocomposites"> nanostructured conductive polymer nanocomposites</a>, <a href="https://publications.waset.org/abstracts/search?q=olfactive%20diagnosis" title=" olfactive diagnosis"> olfactive diagnosis</a> </p> <a href="https://publications.waset.org/abstracts/192210/functional-polyhedral-oligomeric-silsesquioxane-nano-spacer-to-boost-quantum-resistive-vapour-sensors-sensitivity-and-selectivity" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/192210.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">20</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28670</span> Coordinated Voltage Control in a Radial Distribution System</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shivarudraswamy">Shivarudraswamy</a>, <a href="https://publications.waset.org/abstracts/search?q=Anubhav%20Shrivastava"> Anubhav Shrivastava</a>, <a href="https://publications.waset.org/abstracts/search?q=Lakshya%20Bhat"> Lakshya Bhat</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Distributed generation has indeed become a major area of interest in recent years. Distributed Generation can address large number of loads in a power line and hence has better efficiency over the conventional methods. However there are certain drawbacks associated with it, increase in voltage being the major one. This paper addresses the voltage control at the buses for an IEEE 30 bus system by regulating reactive power. For carrying out the analysis, the suitable location for placing distributed generators (DG) is identified through load flow analysis and seeing where the voltage profile is dipping. MATLAB programming is used to regulate the voltage at all buses within +/-5% of the base value even after the introduction of DG’s. Three methods for regulation of voltage are discussed. A sensitivity based analysis is later carried out to determine the priority among the various methods listed in the paper. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=distributed%20generators" title="distributed generators">distributed generators</a>, <a href="https://publications.waset.org/abstracts/search?q=distributed%20system" title=" distributed system"> distributed system</a>, <a href="https://publications.waset.org/abstracts/search?q=reactive%20power" title=" reactive power"> reactive power</a>, <a href="https://publications.waset.org/abstracts/search?q=voltage%20control" title=" voltage control"> voltage control</a> </p> <a href="https://publications.waset.org/abstracts/28710/coordinated-voltage-control-in-a-radial-distribution-system" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/28710.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">500</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28669</span> Carbon Nanofilms on Diamond for All-Carbon Chemical Sensors</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Vivek%20Kumar">Vivek Kumar</a>, <a href="https://publications.waset.org/abstracts/search?q=Alexander%20M.%20Zaitsev"> Alexander M. Zaitsev</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A study on chemical sensing properties of carbon nanofilms on diamond for developing all-carbon chemical sensors is presented. The films were obtained by high temperature graphitization of diamond followed by successive plasma etchings. Characterization of the films was done by Raman spectroscopy, atomic force microscopy, and electrical measurements. Fast and selective response to common organic vapors as seen as sensitivity of electrical conductance was observed. The phenomenological description of the chemical sensitivity is proposed as a function of the surface and bulk material properties of the films. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=chemical%20sensor" title="chemical sensor">chemical sensor</a>, <a href="https://publications.waset.org/abstracts/search?q=carbon%20nanofilm" title=" carbon nanofilm"> carbon nanofilm</a>, <a href="https://publications.waset.org/abstracts/search?q=graphitization%20of%20diamond" title=" graphitization of diamond"> graphitization of diamond</a>, <a href="https://publications.waset.org/abstracts/search?q=plasma%20etching" title=" plasma etching"> plasma etching</a>, <a href="https://publications.waset.org/abstracts/search?q=Raman%20spectroscopy" title=" Raman spectroscopy"> Raman spectroscopy</a>, <a href="https://publications.waset.org/abstracts/search?q=atomic%20force%20microscopy" title=" atomic force microscopy"> atomic force microscopy</a> </p> <a href="https://publications.waset.org/abstracts/20783/carbon-nanofilms-on-diamond-for-all-carbon-chemical-sensors" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/20783.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">446</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28668</span> The Next Generation Neutrinoless Double-Beta Decay Experiment nEXO</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ryan%20Maclellan">Ryan Maclellan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The nEXO Collaboration is designing a very large detector for neutrinoless double beta decay of Xe-136. The nEXO detector is rooted in the current EXO-200 program, which has reached a sensitivity for the half-life of the decay of 1.9x10^25 years with an exposure of 99.8 kg-y. The baseline nEXO design assumes 5 tonnes of liquid xenon, enriched in the mass 136 isotope, within a time projection chamber. The detector is being designed to reach a half-life sensitivity of > 5x10^27 years covering the inverted neutrino mass hierarchy, with 5 years of data. We present the nEXO detector design, the current status of R&D efforts, and the physics case for the experiment. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=double-beta" title="double-beta">double-beta</a>, <a href="https://publications.waset.org/abstracts/search?q=Majorana" title=" Majorana"> Majorana</a>, <a href="https://publications.waset.org/abstracts/search?q=neutrino" title=" neutrino"> neutrino</a>, <a href="https://publications.waset.org/abstracts/search?q=neutrinoless" title=" neutrinoless"> neutrinoless</a> </p> <a href="https://publications.waset.org/abstracts/34405/the-next-generation-neutrinoless-double-beta-decay-experiment-nexo" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/34405.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">423</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28667</span> The Role of Macroeconomic Condition and Volatility in Credit Risk: An Empirical Analysis of Credit Default Swap Index Spread on Structural Models in U.S. Market during Post-Crisis Period</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Xu%20Wang">Xu Wang</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This research builds linear regressions of U.S. macroeconomic condition and volatility measures in the investment grade and high yield Credit Default Swap index spreads using monthly data from March 2009 to July 2016, to study the relationship between different dimensions of macroeconomy and overall credit risk quality. The most significant contribution of this research is systematically examining individual and joint effects of macroeconomic condition and volatility on CDX spreads by including macroeconomic time series that captures different dimensions of the U.S. economy. The industrial production index growth, non-farm payroll growth, consumer price index growth, 3-month treasury rate and consumer sentiment are introduced to capture the condition of real economic activity, employment, inflation, monetary policy and risk aversion respectively. The conditional variance of the macroeconomic series is constructed using ARMA-GARCH model and is used to measure macroeconomic volatility. The linear regression model is conducted to capture relationships between monthly average CDX spreads and macroeconomic variables. The Newey–West estimator is used to control for autocorrelation and heteroskedasticity in error terms. Furthermore, the sensitivity factor analysis and standardized coefficients analysis are conducted to compare the sensitivity of CDX spreads to different macroeconomic variables and to compare relative effects of macroeconomic condition versus macroeconomic uncertainty respectively. This research shows that macroeconomic condition can have a negative effect on CDX spread while macroeconomic volatility has a positive effect on determining CDX spread. Macroeconomic condition and volatility variables can jointly explain more than 70% of the whole variation of the CDX spread. In addition, sensitivity factor analysis shows that the CDX spread is the most sensitive to Consumer Sentiment index. Finally, the standardized coefficients analysis shows that both macroeconomic condition and volatility variables are important in determining CDX spread but macroeconomic condition category of variables have more relative importance in determining CDX spread than macroeconomic volatility category of variables. This research shows that the CDX spread can reflect the individual and joint effects of macroeconomic condition and volatility, which suggests that individual investors or government should carefully regard CDX spread as a measure of overall credit risk because the CDX spread is influenced by macroeconomy. In addition, the significance of macroeconomic condition and volatility variables, such as Non-farm Payroll growth rate and Industrial Production Index growth volatility suggests that the government, should pay more attention to the overall credit quality in the market when macroecnomy is low or volatile. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=autoregressive%20moving%20average%20model" title="autoregressive moving average model">autoregressive moving average model</a>, <a href="https://publications.waset.org/abstracts/search?q=credit%20spread%20puzzle" title=" credit spread puzzle"> credit spread puzzle</a>, <a href="https://publications.waset.org/abstracts/search?q=credit%20default%20swap%20spread" title=" credit default swap spread"> credit default swap spread</a>, <a href="https://publications.waset.org/abstracts/search?q=generalized%20autoregressive%20conditional%20heteroskedasticity%20model" title=" generalized autoregressive conditional heteroskedasticity model"> generalized autoregressive conditional heteroskedasticity model</a>, <a href="https://publications.waset.org/abstracts/search?q=macroeconomic%20conditions" title=" macroeconomic conditions"> macroeconomic conditions</a>, <a href="https://publications.waset.org/abstracts/search?q=macroeconomic%20uncertainty" title=" macroeconomic uncertainty"> macroeconomic uncertainty</a> </p> <a href="https://publications.waset.org/abstracts/89673/the-role-of-macroeconomic-condition-and-volatility-in-credit-risk-an-empirical-analysis-of-credit-default-swap-index-spread-on-structural-models-in-us-market-during-post-crisis-period" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/89673.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">166</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28666</span> Sensing Endocrine Disrupting Chemicals by Virus-Based Structural Colour Nanostructure</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Lee%20Yujin">Lee Yujin</a>, <a href="https://publications.waset.org/abstracts/search?q=Han%20Jiye"> Han Jiye</a>, <a href="https://publications.waset.org/abstracts/search?q=Oh%20Jin-Woo"> Oh Jin-Woo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The adverse effects of endocrine disrupting chemicals (EDCs) has attracted considerable public interests. The benzene-like EDCs structure mimics the mechanisms of hormones naturally occurring in vivo, and alters physiological function of the endocrine system. Although, some of the most representative EDCs such as polychlorinated biphenyls (PCBs) and phthalates compounds already have been prohibited to produce and use in many countries, however, PCBs and phthalates in plastic products as flame retardant and plasticizer are still circulated nowadays. EDCs can be released from products while using and discarding, and it causes serious environmental and health issues. Here, we developed virus-based structurally coloured nanostructure that can detect minute EDCs concentration sensitively and selectively. These structurally coloured nanostructure exhibits characteristic angel-independent colors due to the regular virus bundle structure formation through simple pulling technique. The designed number of different colour bands can be formed through controlling concentration of virus solution and pulling speed. The virus, M-13 bacteriophage, was genetically engineered to react with specific ECDs, typically PCBs and phthalates. M-13 bacteriophage surface (pVIII major coat protein) was decorated with benzene derivative binding peptides (WHW) through phage library method. In the initial assessment, virus-based color sensor was exposed to several organic chemicals including benzene, toluene, phenol, chlorobenzene, and phthalic anhydride. Along with the selectivity evaluation of virus-based colour sensor, it also been tested for sensitivity. 10 to 300 ppm of phthalic anhydride and chlorobenzene were detected by colour sensor, and showed the significant sensitivity with about 90 of dissociation constant. Noteworthy, all measurements were analyzed through principal component analysis (PCA) and linear discrimination analysis (LDA), and exhibited clear discrimination ability upon exposure to 2 categories of EDCs (PCBs and phthalates). Because of its easy fabrication, high sensitivity, and the superior selectivity, M-13 bacteriophage-based color sensor could be a simple and reliable portable sensing system for environmental monitoring, healthcare, social security, and so on. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=M-13%20bacteriophage" title="M-13 bacteriophage">M-13 bacteriophage</a>, <a href="https://publications.waset.org/abstracts/search?q=colour%20sensor" title=" colour sensor"> colour sensor</a>, <a href="https://publications.waset.org/abstracts/search?q=genetic%20engineering" title=" genetic engineering"> genetic engineering</a>, <a href="https://publications.waset.org/abstracts/search?q=EDCs" title=" EDCs"> EDCs</a> </p> <a href="https://publications.waset.org/abstracts/68383/sensing-endocrine-disrupting-chemicals-by-virus-based-structural-colour-nanostructure" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/68383.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">242</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28665</span> Convergence Analysis of Reactive Power Based Schemes Used in Sensorless Control of Induction Motors</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=N.%20Ben%20Si%20Ali">N. Ben Si Ali</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Benalia"> N. Benalia</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Zerzouri"> N. Zerzouri </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Many electronic drivers for the induction motor control are based on sensorless technologies. Speed and torque control is usually attained by application of a speed or position sensor which requires the additional mounting space, reduce the reliability and increase the cost. This paper seeks to analyze dynamical performances and sensitivity to motor parameter changes of reactive power based technique used in sensorless control of induction motors. Validity of theoretical results is verified by simulation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=adaptive%20observers" title="adaptive observers">adaptive observers</a>, <a href="https://publications.waset.org/abstracts/search?q=model%20reference%20adaptive%20system" title=" model reference adaptive system"> model reference adaptive system</a>, <a href="https://publications.waset.org/abstracts/search?q=RP-based%20estimator" title=" RP-based estimator"> RP-based estimator</a>, <a href="https://publications.waset.org/abstracts/search?q=sensorless%20control" title=" sensorless control"> sensorless control</a>, <a href="https://publications.waset.org/abstracts/search?q=stability%20analysis" title=" stability analysis"> stability analysis</a> </p> <a href="https://publications.waset.org/abstracts/21490/convergence-analysis-of-reactive-power-based-schemes-used-in-sensorless-control-of-induction-motors" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/21490.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">546</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28664</span> Performance Parameters of an Abbreviated Breast MRI Protocol</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Andy%20Ho">Andy Ho</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Breast cancer is a common cancer in Australia. Early diagnosis is crucial for improving patient outcomes, as later-stage detection correlates with poorer prognoses. While multiparametric MRI offers superior sensitivity in detecting invasive and high-grade breast cancers compared to conventional mammography, its extended scan duration and high costs limit widespread application. As a result, full protocol MRI screening is typically reserved for patients at elevated risk. Recent advancements in imaging technology have facilitated the development of Abbreviated MRI protocols, which dramatically reduce scan times (<10 minutes compared to >30 minutes for full protocol). The potential for Abbreviated MRI to offer a more time- and cost-efficient alternative has implications for improving patient accessibility, reducing appointment durations, and enhancing compliance—especially relevant for individuals requiring regular annual screening over several decades. The purpose of this study is to assess the diagnostic efficacy of Abbreviated MRI for breast cancer screening among high-risk patients at the Royal Prince Alfred Hospital (RPA). This study aims to determine the sensitivity, specificity, and inter-reader variability of Abbreviated MRI protocols when interpreted by subspecialty-trained Breast Radiologists. A systematic review of the RPA’s electronic Picture Archive and Communication System identified high-risk patients, defined by Australian ‘Medicare Benefits Schedule’ criteria, who underwent Breast MRI from 2021 to 2022. Eligible participants included asymptomatic patients under 50 years old and referred by the High-Risk Clinic due to a high-risk genetic profile or relevant familial history. The MRIs were anonymized, randomized, and interpreted by four Breast Radiologists, each independently completing standardized proforma evaluations. Radiological findings were compared against histopathology as the gold standard or follow-up imaging if biopsies were unavailable. Statistical metrics, including sensitivity, specificity, and inter-reader variability, were assessed. The Fleiss-Kappa analysis demonstrated a fair inter-reader agreement (kappa = 0.25; 95% CI: 0.19–0.32; p < 0.0001). The sensitivity for detecting malignancies was 0.72, with a specificity of 0.92. For benign lesions, sensitivity and specificity were 0.844 and 0.73, respectively. These findings underline the potential of Abbreviated MRI as a reliable screening tool for malignancies with significant specificity, though reduced sensitivity highlights the importance of robust radiologist training and consistent evaluation standards. Abbreviated MRI protocols exhibit promise as a viable screening option for high-risk patients, combining reduced scan times and acceptable diagnostic accuracy. Further work to refine interpretation practices and optimize training is essential to maximize the protocol’s utility in routine clinical screening and facilitate broader accessibility. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=abbreviated" title="abbreviated">abbreviated</a>, <a href="https://publications.waset.org/abstracts/search?q=breast" title=" breast"> breast</a>, <a href="https://publications.waset.org/abstracts/search?q=cancer" title=" cancer"> cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=MRI" title=" MRI"> MRI</a> </p> <a href="https://publications.waset.org/abstracts/194426/performance-parameters-of-an-abbreviated-breast-mri-protocol" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/194426.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">10</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28663</span> Evaluation of the Accuracy of a ‘Two Question Screening Tool’ in the Detection of Intimate Partner Violence in a Primary Healthcare Setting in South Africa</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=A.%20Saimen">A. Saimen</a>, <a href="https://publications.waset.org/abstracts/search?q=E.%20Armstrong"> E. Armstrong</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20Manitshana"> C. Manitshana</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Intimate partner violence (IPV) has been recognised as a global human rights violation. It is universally under diagnosed and the institution of timeous multi-faceted interventions has been noted to benefit IPV victims. Currently, the concept of using a screening tool to detect IPV has not been widely explored in a primary healthcare setting in South Africa, and it was for this reason that this study has been undertaken. A systematic random sampling of 1 in 8 women over a period of 3 months was conducted prospectively at the OPD of a Level 1 Hospital. Participants were asked about their experience of IPV during the past 12 months. The WAST-short, a two-question tool, was used to screen patients for IPV. To verify the result of the screening, women were also asked the remaining questions from the WAST. Data was collected from 400 participants, with a response rate of 99.3%. The prevalence of IPV in the sample was 32%. The WAST-short was shown to have the following operating characteristics: sensitivity 45.2%, specificity 98%,positive predictive value 98%, negative predictive value 79%. The WAST-short lacks sufficient sensitivity and therefore is not an ideal screening tool for this setting. Improvement in the sensitivity of the WAST-short in this setting may be achieved by lowering the threshold for a positive result for IPV screening, and modification of the screening questions to better reflect IPV as understood by the local population. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=domestic%20violence" title="domestic violence">domestic violence</a>, <a href="https://publications.waset.org/abstracts/search?q=intimate%20partner%20violence" title=" intimate partner violence"> intimate partner violence</a>, <a href="https://publications.waset.org/abstracts/search?q=screening" title=" screening"> screening</a>, <a href="https://publications.waset.org/abstracts/search?q=screening%20tools" title=" screening tools"> screening tools</a> </p> <a href="https://publications.waset.org/abstracts/19157/evaluation-of-the-accuracy-of-a-two-question-screening-tool-in-the-detection-of-intimate-partner-violence-in-a-primary-healthcare-setting-in-south-africa" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/19157.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">305</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28662</span> Investigation of the Multiaxial Pedicle Screw Tulip Design Using Finite Element Analysis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=S.%20Daqiqeh%20Rezaei">S. Daqiqeh Rezaei</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Mohajerzadeh"> S. Mohajerzadeh</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20R.%20Sharifi"> M. R. Sharifi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Pedicle screws are used to stabilize vertebrae and treat several types of spinal diseases and injuries. Multiaxial pedicle screws are a type of pedicle screw that increase surgical versatility, but they also increase design complexity. Failure of multiaxial pedicle screws caused by static loading, dynamic loading and fatigue can lead to irreparable damage to the patient. Inappropriate deformation of the multiaxial pedicle screw tulip can cause system failure. Investigation of deformation and stress in these tulips can be employed to optimize multiaxial pedicle screw design. The sensitivity of this matter necessitates precise analyzing and modeling of pedicle screws. In this work, three commercial multiaxial pedicle screw tulips and a newly designed tulip are investigated using finite element analysis. Employing video measuring machine (VMM), tulips are modeled. Afterwards, utilizing ANSYS, static analysis is performed on these models. In the end, stresses and displacements of the models are compared. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=pedicle%20screw" title="pedicle screw">pedicle screw</a>, <a href="https://publications.waset.org/abstracts/search?q=multiaxial%20pedicle%20screw" title=" multiaxial pedicle screw"> multiaxial pedicle screw</a>, <a href="https://publications.waset.org/abstracts/search?q=finite%20element%20analysis" title=" finite element analysis"> finite element analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=static%20analysis" title=" static analysis"> static analysis</a> </p> <a href="https://publications.waset.org/abstracts/29320/investigation-of-the-multiaxial-pedicle-screw-tulip-design-using-finite-element-analysis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/29320.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">368</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28661</span> A Theoretical Modelling and Simulation of a Surface Plasmon Resonance Biosensor for the Detection of Glucose Concentration in Blood and Urine</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Natasha%20Mandal">Natasha Mandal</a>, <a href="https://publications.waset.org/abstracts/search?q=Rakesh%20Singh%20Moirangthem"> Rakesh Singh Moirangthem</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The present work reports a theoretical model to develop a plasmonic biosensor for the detection of glucose concentrations in human blood and urine as the abnormality of glucose label is the major cause of diabetes which becomes a life-threatening disease worldwide. This study is based on the surface plasmon resonance (SPR) sensor applications which is a well-established, highly sensitive, label-free, rapid optical sensing tool. Here we have introduced a sandwich assay of two dielectric spacer layers of MgF2 and BaTiO3which gives better performance compared to commonly used SiO2 and TiO2 dielectric spacers due to their low dielectric loss and higher refractive index. The sensitivity of our proposed sensor was found as 3242 nm/RIU approximately, with an excellent linear response of 0.958, which is higher than the conventional single-layer Au SPR sensor. Further, the sensitivity enhancement is also optimized by coating a few layers of two-dimensional (2D) nanomaterials (e.g., Graphene, h-BN, MXene, MoS2, WS2, etc.) on the sensor chip. Hence, our proposed SPR sensor has the potential for the detection of glucose concentration in blood and urine with enhanced sensitivity and high affinity and could be utilized as a reliable platform for the optical biosensing application in the field of medical diagnosis. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biosensor" title="biosensor">biosensor</a>, <a href="https://publications.waset.org/abstracts/search?q=surface%20plasmon%20resonance" title=" surface plasmon resonance"> surface plasmon resonance</a>, <a href="https://publications.waset.org/abstracts/search?q=dielectric%20spacer" title=" dielectric spacer"> dielectric spacer</a>, <a href="https://publications.waset.org/abstracts/search?q=2D%20nanomaterials" title=" 2D nanomaterials"> 2D nanomaterials</a> </p> <a href="https://publications.waset.org/abstracts/152759/a-theoretical-modelling-and-simulation-of-a-surface-plasmon-resonance-biosensor-for-the-detection-of-glucose-concentration-in-blood-and-urine" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/152759.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">106</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28660</span> Sensitivity Analysis of the Heat Exchanger Design in Net Power Oxy-Combustion Cycle for Carbon Capture</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hirbod%20Varasteh">Hirbod Varasteh</a>, <a href="https://publications.waset.org/abstracts/search?q=Hamidreza%20Gohari%20Darabkhani"> Hamidreza Gohari Darabkhani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The global warming and its impact on climate change is one of main challenges for current century. Global warming is mainly due to the emission of greenhouse gases (GHG) and carbon dioxide (CO<sub>2</sub>) is known to be the major contributor to the GHG emission profile. Whilst the energy sector is the primary source for CO<sub>2</sub> emission, Carbon Capture and Storage (CCS) are believed to be the solution for controlling this emission. Oxyfuel combustion (Oxy-combustion) is one of the major technologies for capturing CO<sub>2</sub> from power plants. For gas turbines, several Oxy-combustion power cycles (Oxyturbine cycles) have been investigated by means of thermodynamic analysis. NetPower cycle is one of the leading oxyturbine power cycles with almost full carbon capture capability from a natural gas fired power plant. In this manuscript, sensitivity analysis of the heat exchanger design in NetPower cycle is completed by means of process modelling. The heat capacity variation and supercritical CO<sub>2 </sub>with gaseous admixtures are considered for multi-zone analysis with Aspen Plus software. It is found that the heat exchanger design has a major role to increase the efficiency of NetPower cycle. The pinch-point analysis is done to extract the composite and grand composite curve for the heat exchanger. In this paper, relationship between the cycle efficiency and the minimum approach temperature (∆Tmin) of the heat exchanger has also been evaluated. Increase in ∆Tmin causes a decrease in the temperature of the recycle flue gases (RFG) and an overall decrease in the required power for the recycled gas compressor. The main challenge in the design of heat exchangers in power plants is a tradeoff between the capital and operational costs. To achieve lower ∆Tmin, larger size of heat exchanger is required. This means a higher capital cost but leading to a better heat recovery and lower operational cost. To achieve this, ∆Tmin is selected from the minimum point in the diagrams of capital and operational costs. This study provides an insight into the NetPower Oxy-combustion cycle’s performance analysis and operational condition based on its heat exchanger design. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=carbon%20capture%20and%20storage" title="carbon capture and storage">carbon capture and storage</a>, <a href="https://publications.waset.org/abstracts/search?q=oxy-combustion" title=" oxy-combustion"> oxy-combustion</a>, <a href="https://publications.waset.org/abstracts/search?q=netpower%20cycle" title=" netpower cycle"> netpower cycle</a>, <a href="https://publications.waset.org/abstracts/search?q=oxy%20turbine%20cycles" title=" oxy turbine cycles"> oxy turbine cycles</a>, <a href="https://publications.waset.org/abstracts/search?q=zero%20emission" title=" zero emission"> zero emission</a>, <a href="https://publications.waset.org/abstracts/search?q=heat%20exchanger%20design" title=" heat exchanger design"> heat exchanger design</a>, <a href="https://publications.waset.org/abstracts/search?q=supercritical%20carbon%20dioxide" title=" supercritical carbon dioxide"> supercritical carbon dioxide</a>, <a href="https://publications.waset.org/abstracts/search?q=oxy-fuel%20power%20plant" title=" oxy-fuel power plant"> oxy-fuel power plant</a>, <a href="https://publications.waset.org/abstracts/search?q=pinch%20point%20analysis" title=" pinch point analysis"> pinch point analysis</a> </p> <a href="https://publications.waset.org/abstracts/85218/sensitivity-analysis-of-the-heat-exchanger-design-in-net-power-oxy-combustion-cycle-for-carbon-capture" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/85218.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">204</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28659</span> Influence of Silicon Carbide Particle Size and Thermo-Mechanical Processing on Dimensional Stability of Al 2124SiC Nanocomposite</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20M.%20Emara">Mohamed M. Emara</a>, <a href="https://publications.waset.org/abstracts/search?q=Heba%20Ashraf"> Heba Ashraf</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study is to investigation the effect of silicon carbide (SiC) particle size and thermo-mechanical processing on dimensional stability of aluminum alloy 2124. Three combinations of SiC weight fractions are investigated, 2.5, 5, and 10 wt. % with different SiC particle sizes (25 μm, 5 μm, and 100nm) were produced using mechanical ball mill. The standard testing samples were fabricated using powder metallurgy technique. Both samples, prior and after extrusion, were heated from room temperature up to 400ºC in a dilatometer at different heating rates, that is, 10, 20, and 40ºC/min. The analysis showed that for all materials, there was an increase in length change as temperature increased and the temperature sensitivity of aluminum alloy decreased in the presence of both micro and nano-sized silicon carbide. For all conditions, nanocomposites showed better dimensional stability compared to conventional Al 2124/SiC composites. The after extrusion samples showed better thermal stability and less temperature sensitivity for the aluminum alloy for both micro and nano-sized silicon carbide. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=aluminum%202124%20metal%20matrix%20composite" title="aluminum 2124 metal matrix composite">aluminum 2124 metal matrix composite</a>, <a href="https://publications.waset.org/abstracts/search?q=SiC%20nano-sized%20reinforcements" title=" SiC nano-sized reinforcements"> SiC nano-sized reinforcements</a>, <a href="https://publications.waset.org/abstracts/search?q=powder%20metallurgy" title=" powder metallurgy"> powder metallurgy</a>, <a href="https://publications.waset.org/abstracts/search?q=extrusion%20mechanical%20ball%20mill" title=" extrusion mechanical ball mill"> extrusion mechanical ball mill</a>, <a href="https://publications.waset.org/abstracts/search?q=dimensional%20stability" title=" dimensional stability"> dimensional stability</a> </p> <a href="https://publications.waset.org/abstracts/20367/influence-of-silicon-carbide-particle-size-and-thermo-mechanical-processing-on-dimensional-stability-of-al-2124sic-nanocomposite" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/20367.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">526</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28658</span> Biopsy or Biomarkers: Which Is the Sample of Choice in Assessment of Liver Fibrosis?</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=S.%20H.%20Atef">S. H. Atef</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20H.%20Mahmoud"> N. H. Mahmoud</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Abdrahman"> S. Abdrahman</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Fattoh"> A. Fattoh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: The aim of the study is to assess the diagnostic value of fibrotest and hyaluronic acid in discriminate between insignificant and significant fibrosis. Also, to find out if these parameters could replace liver biopsy which is currently used for selection of chronic hepatitis C patients eligible for antiviral therapy. Study design: This study was conducted on 52 patients with HCV RNA detected by polymerase chain reaction (PCR) who had undergone liver biopsy and attending the internal medicine clinic at Ain Shams University Hospital. Liver fibrosis was evaluated according to the METAVIR scoring system on a scale of F0 to F4. Biochemical markers assessed were: alpha-2 macroglobulin (α2-MG), apolipoprotein A1 (Apo-A1), haptoglobin, gamma-glutamyl transferase (GGT), total bilirubin (TB) and hyaluronic acid (HA). The fibrotest score was computed after adjusting for age and gender. Predictive values and ROC curves were used to assess the accuracy of fibrotest and HA results. Results: For fibrotest, the observed area under curve for the discrimination between minimal or no fibrosis (F0-F1) and significant fibrosis (F2-F4) was 0.6736 for cutoff value 0.19 with sensitivity of 84.2% and specificity of 85.7%. For HA, the sensitivity was 89.5% and specificity was 85.7% and area under curve was 0.540 at the best cutoff value 71 mg/dL. Multi-use of both parameters, HA at 71 mg/dL with fibrotest score at 0.22 give a sensitivity 89.5%, specificity 100 and efficacy 92.3% (AUC 0.895). Conclusion: The use of both fibrotest score and HA could be as alternative to biopsy in most patients with chronic hepaitis C putting in consideration some limitations of the proposed markers in evaluating liver fibrosis. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=fibrotest" title="fibrotest">fibrotest</a>, <a href="https://publications.waset.org/abstracts/search?q=liver%20fibrosis" title=" liver fibrosis"> liver fibrosis</a>, <a href="https://publications.waset.org/abstracts/search?q=HCV%20RNA" title=" HCV RNA"> HCV RNA</a>, <a href="https://publications.waset.org/abstracts/search?q=biochemical%20markers" title=" biochemical markers"> biochemical markers</a> </p> <a href="https://publications.waset.org/abstracts/37231/biopsy-or-biomarkers-which-is-the-sample-of-choice-in-assessment-of-liver-fibrosis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/37231.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">287</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28657</span> Optimal Rotor Design of an 150kW-Class IPMSM through the 3D Voltage-Inductance Map Analysis Method</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Eung-Seok%20Park">Eung-Seok Park</a>, <a href="https://publications.waset.org/abstracts/search?q=Tae-Chul%20Jeong"> Tae-Chul Jeong</a>, <a href="https://publications.waset.org/abstracts/search?q=Hyun-Jong%20Park"> Hyun-Jong Park</a>, <a href="https://publications.waset.org/abstracts/search?q=Hyun-Woo%20Jun"> Hyun-Woo Jun</a>, <a href="https://publications.waset.org/abstracts/search?q=Dong-Woo%20Kang"> Dong-Woo Kang</a>, <a href="https://publications.waset.org/abstracts/search?q=Ju%20Lee"> Ju Lee </a> </p> <p class="card-text"><strong>Abstract:</strong></p> This presents a methodology to determine detail design directions of an 150kW-class IPMSM (interior permanent magnet synchronous motor) and its detail design. The basic design of the stator and rotor was conducted. After dividing the designed models into the best cases and the worst cases based on rotor shape parameters, Sensitivity analysis and 3D Voltage-Inductance Map (3D EL-Map) parameters were analyzed. Then, the design direction for the final model was predicted. Based on the prediction, the final model was extracted with Trend analysis. Lastly, the final model was validated with experiments. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=PMSM" title="PMSM">PMSM</a>, <a href="https://publications.waset.org/abstracts/search?q=optimal%20design" title=" optimal design"> optimal design</a>, <a href="https://publications.waset.org/abstracts/search?q=rotor%20design" title=" rotor design"> rotor design</a>, <a href="https://publications.waset.org/abstracts/search?q=voltage-inductance%20map" title=" voltage-inductance map"> voltage-inductance map</a> </p> <a href="https://publications.waset.org/abstracts/25639/optimal-rotor-design-of-an-150kw-class-ipmsm-through-the-3d-voltage-inductance-map-analysis-method" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/25639.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">673</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28656</span> Effect of Removing Hub Domain on Human CaMKII Isoforms Sensitivity to Calcium/Calmodulin</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ravid%20Inbar">Ravid Inbar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> CaMKII (calcium-calmodulin dependent protein kinase II) makes up 2% of the protein in our brain and has a critical role in memory formation and long-term potentiation of neurons. Despite this, research has yet to uncover the role of one of the domains on the activation of this kinase. The following proposes to express the protein without the hub domain in E. coli, leaving only the kinase and regulatory segment of the protein. Next, a series of kinase assays will be conducted to elucidate the role the hub domain plays on CaMKII sensitivity to calcium/calmodulin activation. The hub domain may be important for activation; however, it may also be a variety of domains working together to influence protein activation and not the hub alone. Characterization of a protein is critical to the future understanding of the protein's function, as well as for producing pharmacological targets in cases of patients with diseases. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=CaMKII" title="CaMKII">CaMKII</a>, <a href="https://publications.waset.org/abstracts/search?q=hub%20domain" title=" hub domain"> hub domain</a>, <a href="https://publications.waset.org/abstracts/search?q=kinase%20assays" title=" kinase assays"> kinase assays</a>, <a href="https://publications.waset.org/abstracts/search?q=kinase%20%2B%20reg%20seg" title=" kinase + reg seg"> kinase + reg seg</a> </p> <a href="https://publications.waset.org/abstracts/157748/effect-of-removing-hub-domain-on-human-camkii-isoforms-sensitivity-to-calciumcalmodulin" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/157748.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">89</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28655</span> Stabilizing a Failed Slope in Islamabad, Pakistan</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Muhammad%20Umer%20Zubair">Muhammad Umer Zubair</a>, <a href="https://publications.waset.org/abstracts/search?q=Kamran%20Akhtar"> Kamran Akhtar</a>, <a href="https://publications.waset.org/abstracts/search?q=Muhammad%20Arsalan%20Khan"> Muhammad Arsalan Khan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper is based on a research carried out on a failed slope in Defence Housing Authority (DHA) Phase I, Islamabad. The research included determination of Soil parameters, Site Surveying and Cost Estimation. Apart from these, the use of three dimensional (3D) slope stability analysis in conjunction with two dimensional (2D) analysis was used determination of slope conditions. In addition collection of soil reports, a detailed survey was carried out to create a 3D model in Surfer 8 software. 2D cross-sections that needed to be analyzed for stability were generated from 3D model. Slope stability softwares, Rocscience Slide 6.0 and Clara-W were employed for 2D and 3D Analyses respectively which have the ability to solve complex mathematical functions. Results of the analyses were used to confirm site conditions and the threats were identified to recommend suitable remedies.The most effective remedy was suggested for slope stability after analyzing all remedies in software Slide 6 and its feasibility was determined through cost benefit analysis. This paper should be helpful to Geotechnical engineers, design engineers and the organizations working with slope stability. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=slope%20stability" title="slope stability">slope stability</a>, <a href="https://publications.waset.org/abstracts/search?q=Rocscience" title=" Rocscience"> Rocscience</a>, <a href="https://publications.waset.org/abstracts/search?q=Clara%20W." title=" Clara W."> Clara W.</a>, <a href="https://publications.waset.org/abstracts/search?q=2d%20analysis" title=" 2d analysis"> 2d analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=3D%20analysis" title=" 3D analysis"> 3D analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=sensitivity%20analysis" title=" sensitivity analysis"> sensitivity analysis</a> </p> <a href="https://publications.waset.org/abstracts/18441/stabilizing-a-failed-slope-in-islamabad-pakistan" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/18441.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">522</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28654</span> Modeling and Analysis of Laser Sintering Process Scanning Time for Optimal Planning and Control</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Agarana%20Michael%20C.">Agarana Michael C.</a>, <a href="https://publications.waset.org/abstracts/search?q=Akinlabi%20Esther%20T."> Akinlabi Esther T.</a>, <a href="https://publications.waset.org/abstracts/search?q=Pule%20Kholopane"> Pule Kholopane</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In order to sustain the advantages of an advanced manufacturing technique, such as laser sintering, minimization of total processing cost of the parts being produced is very important. An efficient time management would usually very important in optimal cost attainment which would ultimately result in an efficient advanced manufacturing process planning and control. During Laser Scanning Process Scanning (SLS) procedures it is possible to adjust various manufacturing parameters which are used to influence the improvement of various mechanical and other properties of the products. In this study, Modelling and mathematical analysis, including sensitivity analysis, of the laser sintering process time were carried out. The results of the analyses were represented with graphs, from where conclusions were drawn. It was specifically observed that achievement of optimal total scanning time is key for economic efficiency which is required for sustainability of the process. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=modeling%20and%20analysis" title="modeling and analysis">modeling and analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=optimal%20planning%20and%20control" title=" optimal planning and control"> optimal planning and control</a>, <a href="https://publications.waset.org/abstracts/search?q=laser%20sintering%20process" title=" laser sintering process"> laser sintering process</a>, <a href="https://publications.waset.org/abstracts/search?q=scanning%20time" title=" scanning time"> scanning time</a> </p> <a href="https://publications.waset.org/abstracts/158820/modeling-and-analysis-of-laser-sintering-process-scanning-time-for-optimal-planning-and-control" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/158820.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">98</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28653</span> Evaluating Gender Sensitivity and Policy: Case Study of an EFL Textbook in Armenia </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ani%20Kojoyan">Ani Kojoyan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Linguistic studies have been investigating a connection between gender and linguistic development since 1970s. Scholars claim that gender differences in first and second language learning are socially constructed. Recent studies to language learning and gender reveal that second language acquisition is also a social phenomenon directly influencing one’s gender identity. Those responsible for designing language learning-teaching materials should be encouraged to understand the importance of and address the gender sensitivity accurately in textbooks. Writing or compiling a textbook is not an easy task; it requires strong academic abilities, patience, and experience. For a long period of time Armenia has been involved in the compilation process of a number of foreign language textbooks. However, there have been very few discussions or evaluations of those textbooks which will allow specialists to theorize that practice. The present paper focuses on the analysis of gender sensitivity issues and policy aspects involved in an EFL textbook. For the research the following material has been considered – “A Basic English Grammar: Morphology”, first printed in 2011. The selection of the material is not accidental. First, the mentioned textbook has been widely used in university teaching over years. Secondly, in Armenia “A Basic English Grammar: Morphology” has considered one of the most successful English grammar textbooks in a university teaching environment and served a source-book for other authors to compile and design their textbooks. The present paper aims to find out whether an EFL textbook is gendered in the Armenian teaching environment, and whether the textbook compilers are aware of gendered messages while compiling educational materials. It also aims at investigating students’ attitude toward the gendered messages in those materials. And finally, it also aims at increasing the gender sensitivity among book compilers and educators in various educational settings. For this study qualitative and quantitative research methods of analyses have been applied, the quantitative – in terms of carrying out surveys among students (45 university students, 18-25 age group), and the qualitative one – by discourse analysis of the material and conducting in-depth and semi-structured interviews with the Armenian compilers of the textbook (interviews with 3 authors). The study is based on passive and active observations and teaching experience done in a university classroom environment in 2014-2015, 2015-2016. The findings suggest that the discussed and analyzed teaching materials (145 extracts and examples) include traditional examples of intensive use of language and role-modelling, particularly, men are mostly portrayed as active, progressive, aggressive, whereas women are often depicted as passive and weak. These modeled often serve as a ‘reliable basis’ for reinforcing the traditional roles that have been projected on female and male students. The survey results also show that such materials contribute directly to shaping learners’ social attitudes and expectations around issues of gender. The applied techniques and discussed issues can be generalized and applied to other foreign language textbook compilation processes, since those principles, regardless of a language, are mostly the same. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=EFL%20textbooks" title="EFL textbooks">EFL textbooks</a>, <a href="https://publications.waset.org/abstracts/search?q=gender%20policy" title=" gender policy"> gender policy</a>, <a href="https://publications.waset.org/abstracts/search?q=gender%20sensitivity" title=" gender sensitivity"> gender sensitivity</a>, <a href="https://publications.waset.org/abstracts/search?q=qualitative%20and%20quantitative%20research%20methods" title=" qualitative and quantitative research methods "> qualitative and quantitative research methods </a> </p> <a href="https://publications.waset.org/abstracts/69228/evaluating-gender-sensitivity-and-policy-case-study-of-an-efl-textbook-in-armenia" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/69228.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">195</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28652</span> Assessment of Occupational Exposure and Individual Radio-Sensitivity in People Subjected to Ionizing Radiation </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Oksana%20G.%20Cherednichenko">Oksana G. Cherednichenko</a>, <a href="https://publications.waset.org/abstracts/search?q=Anastasia%20L.%20Pilyugina"> Anastasia L. Pilyugina</a>, <a href="https://publications.waset.org/abstracts/search?q=Sergey%20N.Lukashenko"> Sergey N.Lukashenko</a>, <a href="https://publications.waset.org/abstracts/search?q=Elena%20G.%20Gubitskaya"> Elena G. Gubitskaya</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The estimation of accumulated radiation doses in people professionally exposed to ionizing radiation was performed using methods of biological (chromosomal aberrations frequency in lymphocytes) and physical (radionuclides analysis in urine, whole-body radiation meter, individual thermoluminescent dosimeters) dosimetry. A group of 84 "A" category employees after their work in the territory of former Semipalatinsk test site (Kazakhstan) was investigated. The dose rate in some funnels exceeds 40 μSv/h. After radionuclides determination in urine using radiochemical and WBC methods, it was shown that the total effective dose of personnel internal exposure did not exceed 0.2 mSv/year, while an acceptable dose limit for staff is 20 mSv/year. The range of external radiation doses measured with individual thermo-luminescent dosimeters was 0.3-1.406 µSv. The cytogenetic examination showed that chromosomal aberrations frequency in staff was 4.27±0.22%, which is significantly higher than at the people from non-polluting settlement Tausugur (0.87±0.1%) (р ≤ 0.01) and citizens of Almaty (1.6±0.12%) (р≤ 0.01). Chromosomal type aberrations accounted for 2.32±0.16%, 0.27±0.06% of which were dicentrics and centric rings. The cytogenetic analysis of different types group radiosensitivity among «professionals» (age, sex, ethnic group, epidemiological data) revealed no significant differences between the compared values. Using various techniques by frequency of dicentrics and centric rings, the average cumulative radiation dose for group was calculated, and that was 0.084-0.143 Gy. To perform comparative individual dosimetry using physical and biological methods of dose assessment, calibration curves (including own ones) and regression equations based on general frequency of chromosomal aberrations obtained after irradiation of blood samples by gamma-radiation with the dose rate of 0,1 Gy/min were used. Herewith, on the assumption of individual variation of chromosomal aberrations frequency (1–10%), the accumulated dose of radiation varied 0-0.3 Gy. The main problem in the interpretation of individual dosimetry results is reduced to different reaction of the objects to irradiation - radiosensitivity, which dictates the need of quantitative definition of this individual reaction and its consideration in the calculation of the received radiation dose. The entire examined contingent was assigned to a group based on the received dose and detected cytogenetic aberrations. Radiosensitive individuals, at the lowest received dose in a year, showed the highest frequency of chromosomal aberrations (5.72%). In opposite, radioresistant individuals showed the lowest frequency of chromosomal aberrations (2.8%). The cohort correlation according to the criterion of radio-sensitivity in our research was distributed as follows: radio-sensitive (26.2%) — medium radio-sensitivity (57.1%), radioresistant (16.7%). Herewith, the dispersion for radioresistant individuals is 2.3; for the group with medium radio-sensitivity — 3.3; and for radio-sensitive group — 9. These data indicate the highest variation of characteristic (reactions to radiation effect) in the group of radio-sensitive individuals. People with medium radio-sensitivity show significant long-term correlation (0.66; n=48, β ≥ 0.999) between the values of doses defined according to the results of cytogenetic analysis and dose of external radiation obtained with the help of thermoluminescent dosimeters. Mathematical models based on the type of violation of the radiation dose according to the professionals radiosensitivity level were offered. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biodosimetry" title="biodosimetry">biodosimetry</a>, <a href="https://publications.waset.org/abstracts/search?q=chromosomal%20aberrations" title=" chromosomal aberrations"> chromosomal aberrations</a>, <a href="https://publications.waset.org/abstracts/search?q=ionizing%20radiation" title=" ionizing radiation"> ionizing radiation</a>, <a href="https://publications.waset.org/abstracts/search?q=radiosensitivity" title=" radiosensitivity"> radiosensitivity</a> </p> <a href="https://publications.waset.org/abstracts/74455/assessment-of-occupational-exposure-and-individual-radio-sensitivity-in-people-subjected-to-ionizing-radiation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/74455.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">184</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28651</span> Using HABIT to Estimate the Concentration of CO2 and H2SO4 for Kuosheng Nuclear Power Plant</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Y.%20Chiang">Y. Chiang</a>, <a href="https://publications.waset.org/abstracts/search?q=W.%20Y.%20Li"> W. Y. Li</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20R.%20Wang"> J. R. Wang</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20W.%20Chen"> S. W. Chen</a>, <a href="https://publications.waset.org/abstracts/search?q=W.%20S.%20Hsu"> W. S. Hsu</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20H.%20Yang"> J. H. Yang</a>, <a href="https://publications.waset.org/abstracts/search?q=Y.%20S.%20Tseng"> Y. S. Tseng</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20Shih"> C. Shih </a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this research, the HABIT code was used to estimate the concentration under the CO<sub>2</sub> and H<sub>2</sub>SO<sub>4</sub> storage burst conditions for Kuosheng nuclear power plant (NPP). The Final Safety Analysis Report (FSAR) and reports were used in this research. In addition, to evaluate the control room habitability for these cases, the HABIT analysis results were compared with the R.G. 1.78 failure criteria. The comparison results show that the HABIT results are below the criteria. Additionally, some sensitivity studies (stability classification, wind speed and control room intake rate) were performed in this study. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=BWR" title="BWR">BWR</a>, <a href="https://publications.waset.org/abstracts/search?q=HABIT" title=" HABIT"> HABIT</a>, <a href="https://publications.waset.org/abstracts/search?q=habitability" title=" habitability"> habitability</a>, <a href="https://publications.waset.org/abstracts/search?q=Kuosheng" title=" Kuosheng"> Kuosheng</a> </p> <a href="https://publications.waset.org/abstracts/83491/using-habit-to-estimate-the-concentration-of-co2-and-h2so4-for-kuosheng-nuclear-power-plant" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/83491.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">489</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28650</span> Investigation of Airship Motion Sensitivity to Geometric Parameters</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Han%20Ding">Han Ding</a>, <a href="https://publications.waset.org/abstracts/search?q=Wang%20Xiaoliang"> Wang Xiaoliang</a>, <a href="https://publications.waset.org/abstracts/search?q=Duan%20Dengping"> Duan Dengping</a> </p> <p class="card-text"><strong>Abstract:</strong></p> During the process of airship design, the layout and the geometric shape of the hull and fins are crucial to the motion characteristics of the airship. In this paper, we obtained the quantification motion sensitivity of the airship to geometric parameters through turning circles and horizontal/vertical zigzag maneuvers by the parameterization of airship shape and building the dynamic model using Lagrangian approach and MATLAB Simulink program. In the dynamics simulation program, the affection of geometric parameters to the mass, center of gravity, moments of inertia, product of inertia, added mass and the aerodynamic forces and moments have been considered. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=airship" title="airship">airship</a>, <a href="https://publications.waset.org/abstracts/search?q=Lagrangian%20approach" title=" Lagrangian approach"> Lagrangian approach</a>, <a href="https://publications.waset.org/abstracts/search?q=turning%20circles" title=" turning circles"> turning circles</a>, <a href="https://publications.waset.org/abstracts/search?q=horizontal%2Fvertical%20zigzag%20maneuvers" title=" horizontal/vertical zigzag maneuvers"> horizontal/vertical zigzag maneuvers</a> </p> <a href="https://publications.waset.org/abstracts/40146/investigation-of-airship-motion-sensitivity-to-geometric-parameters" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/40146.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">425</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28649</span> Effect of a Single Injection of hCG on Testosterone Concentration in Male Alpacas</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=A.%20ElZawam">A. ElZawam</a>, <a href="https://publications.waset.org/abstracts/search?q=D.%20McLean"> D. McLean</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Tibary"> A. Tibary</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In alpaca, age at puberty is variable and the factors regulating the pattern of puberty and sexual maturation are a subject of controversy. Plasma testosterone level is often used as an indicator of sexual maturity. Our hypothesis is that hCG treatment will cause an increase in testosterone level that is correlated with animal age. The specific aim was to investigate the testicular tissue response to a single hCG injection by monitoring the serum testosterone concentration. Eighty four (n=84) males ranging in age from 6 to 60 months were used. Alpacas were grouped based on their ages into 15 groups. Each group had three to five male animals. Blood samples were collected from the jugular vein before treatment with hCG and 2 hours after intravenous administration of 3000 IU of hCG (Chorulon®). The serum was harvested and stored at -20ºC until the analysis. The effect of age on basal testosterone level and response to hCG treatment was evaluated by Analysis of Variance. As a result, basal serum testosterone concentrations were very low (<0.1ng/ml) until 9 months of age. Although basal serum testosterone concentrations increased steadily with age there was a significant variation amongst males within the same age group. Administration of 3000 IU of hCG, resulted in an average increase of 50% (P<0.05) in serum testosterone concentration after 2 hours. The percentage increase in serum testosterone in response to hCG stimulation varied from 51 to 81%. There was no correlation between the degree of response and age. However, the response to hCG injection presented two modes of increase depending on the age of animals. The first mode occurred at ages 9 to 14 months and the second mode was observed between 22 and 36 months. In conclusion, our results suggest that testicular growth and sensitivity to LH stimulation may be bimodal in the male alpaca with a rapid increase in growth and sensitivity between 9 and 14 months of age and a second phase of increased responsiveness after 21 months of ages. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=alpaca" title="alpaca">alpaca</a>, <a href="https://publications.waset.org/abstracts/search?q=testosterone" title=" testosterone"> testosterone</a>, <a href="https://publications.waset.org/abstracts/search?q=hCG" title=" hCG"> hCG</a>, <a href="https://publications.waset.org/abstracts/search?q=animal%20science" title=" animal science"> animal science</a> </p> <a href="https://publications.waset.org/abstracts/19284/effect-of-a-single-injection-of-hcg-on-testosterone-concentration-in-male-alpacas" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/19284.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">570</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28648</span> Ethylene Sensitivity in Orchids and Its Control Using 1-MCP: A Review</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Parviz%20Almasi">Parviz Almasi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Ethylene is produced as a gaseous growth regulator in all plants and their constructive parts such as roots, stems, leaves, flowers and fruits. It is considered a multifunctional phytohormone that regulates both growths including flowering, fruit ripening, inhibition of root growth, and senescence such as senescence of leaves and flowers and etc. In addition, exposure to external ethylene is caused some changes that are often undesirable and harmful. Some flowers are more sensitive to others and when exposed to ethylene; their aging process is hastened. 1-MCP is an exogenous and endogenous ethylene action inhibitor, which binds to the ethylene receptors in the plants and prevents ethylene-dependent reactions. The binding affinity of 1- MCP for the receptors is about 10 times more than ethylene. Hence, 1-MCP can be a potential candidate for controlling of ethylene injury in horticultural crops. This review integrates knowledge of ethylene biosynthesis in the plants and also a mode of action of 1-MCP in preventing of ethylene injury. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ethylene%20injury" title="ethylene injury">ethylene injury</a>, <a href="https://publications.waset.org/abstracts/search?q=biosynthesis" title=" biosynthesis"> biosynthesis</a>, <a href="https://publications.waset.org/abstracts/search?q=ethylene%20sensitivity" title=" ethylene sensitivity"> ethylene sensitivity</a>, <a href="https://publications.waset.org/abstracts/search?q=1-MCP" title=" 1-MCP"> 1-MCP</a> </p> <a href="https://publications.waset.org/abstracts/151840/ethylene-sensitivity-in-orchids-and-its-control-using-1-mcp-a-review" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/151840.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">100</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28647</span> Perspective of Community Health Workers on The Sustainability of Primary Health Care</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Dan%20Richard%20D.%20Fernandez">Dan Richard D. Fernandez</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study determined the perspectives of community health workers’ perspectives in the sustainability of primary health care. Eight community health workers, two community officials and a rural health midwife in a rural community in the in the Philippines were enjoined to share their perspectives in the sustainability of primary health care. The study utilized the critical research method. The critical research assumes that there are ‘dominated’ or ‘marginalized’ groups whose interests are not best served by existing societal structures. Their experiences highlighted that the challenges of their role include unkind and uncooperative patients, the lack of institutional support mechanisms and conflict of their roles with their family responsibilities. Their most revealing insight is the belief that primary health care is within their grasp. Finally, they believe that the burden to sustain primary health care rests on their shoulders alone. This study establishes that Multi-stakeholder participation is and Gender-sensitivity is integral to the sustainability of Primary Health Care. It also observed that the ingrained Expert-Novice or Top-down Management Culture and the marginalisation of BHWs within the system is a threat to PHC sustainability. This study also recommends to expand the study and to involve the local government units and academe in lobbying the integration of gender-sensitivity and multi-stake participatory approaches to health workforce policies. Finally, this study recognised that the CHWs’ role is indispensable to the sustainability of primary health care. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=community%20health%20workers" title="community health workers">community health workers</a>, <a href="https://publications.waset.org/abstracts/search?q=multi-stakeholder%20participation" title=" multi-stakeholder participation"> multi-stakeholder participation</a>, <a href="https://publications.waset.org/abstracts/search?q=sustainability" title=" sustainability"> sustainability</a>, <a href="https://publications.waset.org/abstracts/search?q=gender-sensitivity" title=" gender-sensitivity"> gender-sensitivity</a> </p> <a href="https://publications.waset.org/abstracts/33335/perspective-of-community-health-workers-on-the-sustainability-of-primary-health-care" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/33335.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">544</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28646</span> Prevalence of Uropathogens in Diabetic Patients with Urinary Tract Infection and Antimicrobial Sensitivity Pattern at Bangladesh</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohammad%20Saifuddin">Mohammad Saifuddin</a>, <a href="https://publications.waset.org/abstracts/search?q=Shahjada%20Selim"> Shahjada Selim</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Patients with diabetes mellitus (DM) are prone to develop infection, especially urinary tract infection (UTI) in comparison with non-diabetics. Due to the emergence of multidrug resistant (MDR) uropathogenic strains, the choice of antimicrobial agent is sometimes difficult. This study is designed to reveal the distribution of uropathogens in Diabetic patients and corresponding sensitivity patterns and to correlate the microbiological results with various clinical parameters. A nine-month retrospective review of 100 urine culture reports of Diabetic patients from January 2015 to September 2015 from semiurbanmultispeciality hospital of Feni, Bangladesh were analyzed. Only Diabetic patients were included in this study who were clinically diagnosed as UTI patients with a corresponding urine culture showing a bacterial count of ˃105cfu/ml.Out of 100 patients with UTI, 39 (39%) were male, and 61 (61%) were female. Organisms grown in urine culture were Escherichia coli (64) followed by Klebsiella (11), Proteus (7), Staph Aureus (4), Pseudomonas (4), Acinetobacter (3), Sreptococcus(3), Enterococcus (2 ) and one each of Enterobacter and Fungi. Overall sensitivity pattern in decreasing order of various commonly used antibiotics was Meropenem (89%), Nitrofurantoin (86%), Amikacin (81%), Ceftriaxone (68%), Cefuroxime (61%), Cefixime (39%), Quinolones (28%), Amoxicillin (16%). The significance of the study lies in the determination of common pathogens in diabetic patients with UTI and the resistance pattern of antibiotics so that physicians and pharmacists get the proper information rationalizing the rational use of antibiotics. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bangladesh" title="Bangladesh">Bangladesh</a>, <a href="https://publications.waset.org/abstracts/search?q=Diabetes%20Mellitus" title=" Diabetes Mellitus"> Diabetes Mellitus</a>, <a href="https://publications.waset.org/abstracts/search?q=E.%20coli" title=" E. coli"> E. coli</a>, <a href="https://publications.waset.org/abstracts/search?q=urinary%20tract%20infection" title=" urinary tract infection"> urinary tract infection</a> </p> <a href="https://publications.waset.org/abstracts/58708/prevalence-of-uropathogens-in-diabetic-patients-with-urinary-tract-infection-and-antimicrobial-sensitivity-pattern-at-bangladesh" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/58708.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">310</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28645</span> Surface-Enhanced Raman Spectroscopy on Gold Nanoparticles in the Kidney Disease</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Leonardo%20C.%20Pacheco-Londo%C3%B1o">Leonardo C. Pacheco-Londoño</a>, <a href="https://publications.waset.org/abstracts/search?q=Nataly%20J%20Galan-Freyle"> Nataly J Galan-Freyle</a>, <a href="https://publications.waset.org/abstracts/search?q=Lisandro%20Pacheco-Lugo"> Lisandro Pacheco-Lugo</a>, <a href="https://publications.waset.org/abstracts/search?q=Antonio%20Acosta-Hoyos"> Antonio Acosta-Hoyos</a>, <a href="https://publications.waset.org/abstracts/search?q=Elkin%20Navarro"> Elkin Navarro</a>, <a href="https://publications.waset.org/abstracts/search?q=Gustavo%20Aroca-Martinez"> Gustavo Aroca-Martinez</a>, <a href="https://publications.waset.org/abstracts/search?q=Karin%20Rond%C3%B3n-Payares"> Karin Rondón-Payares</a>, <a href="https://publications.waset.org/abstracts/search?q=Alberto%20C.%20Espinosa-Garavito"> Alberto C. Espinosa-Garavito</a>, <a href="https://publications.waset.org/abstracts/search?q=Samuel%20P.%20Hern%C3%A1ndez-Rivera"> Samuel P. Hernández-Rivera</a> </p> <p class="card-text"><strong>Abstract:</strong></p> At the Life Science Research Center at Simon Bolivar University, a primary focus is the diagnosis of various diseases, and the use of gold nanoparticles (Au-NPs) in diverse biomedical applications is continually expanding. In the present study, Au-NPs were employed as substrates for Surface-Enhanced Raman Spectroscopy (SERS) aimed at diagnosing kidney diseases arising from Lupus Nephritis (LN), preeclampsia (PC), and Hypertension (H). Discrimination models were developed for distinguishing patients with and without kidney diseases based on the SERS signals from urine samples by partial least squares-discriminant analysis (PLS-DA). A comparative study of the Raman signals across the three conditions was conducted, leading to the identification of potential metabolite signals. Model performance was assessed through cross-validation and external validation, determining parameters like sensitivity and specificity. Additionally, a secondary analysis was performed using machine learning (ML) models, wherein different ML algorithms were evaluated for their efficiency. Models’ validation was carried out using cross-validation and external validation, and other parameters were determined, such as sensitivity and specificity; the models showed average values of 0.9 for both parameters. Additionally, it is not possible to highlight this collaborative effort involved two university research centers and two healthcare institutions, ensuring ethical treatment and informed consent of patient samples. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=SERS" title="SERS">SERS</a>, <a href="https://publications.waset.org/abstracts/search?q=Raman" title=" Raman"> Raman</a>, <a href="https://publications.waset.org/abstracts/search?q=PLS-DA" title=" PLS-DA"> PLS-DA</a>, <a href="https://publications.waset.org/abstracts/search?q=kidney%20diseases" title=" kidney diseases"> kidney diseases</a> </p> <a href="https://publications.waset.org/abstracts/174893/surface-enhanced-raman-spectroscopy-on-gold-nanoparticles-in-the-kidney-disease" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/174893.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light 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