Understanding faulty proteins

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class="gdm-header__link-inner"> <strong class="gdm-header__title"> Events </strong> <span class="gdm-header__description"> <span class="glue-visually-hidden"> — </span>Meet our team and learn more about our research </span> </span> </a> </li><li class="glue-header__item"> <a class="glue-header__link" data-gtm-tag="header-selection" href="/discover/the-podcast/"> <span class="gdm-header__link-inner"> <strong class="gdm-header__title"> The Podcast </strong> <span class="gdm-header__description"> <span class="glue-visually-hidden"> — </span>Uncover the extraordinary ways AI is transforming our world </span> </span> </a> </li> </ul> <div class="gdm-header__featured"> <p class="gdm-header__featured-title glue-label">Latest posts</p> <ul class="gdm-header__featured-items glue-no-bullet"> <li> <a class="glue-header__link gdm-header__featured-item" data-gtm-tag="header-selection" href="https://blog.google/technology/google-deepmind/alphaqubit-quantum-error-correction/" rel="noopener" target="_blank"> <picture class="picture gdm-header__featured-image"> <source type="image/webp" width="264" height="156" srcset="https://lh3.googleusercontent.com/5E3cNGtS0t4rKlZ1BYBXU93xYwONyYQqIpmY-askDQ9jpTPVb-JH20Gk3wxcMdokGY2ygzjj_crFIy-MYFY-VnekgQVzbSs0Y64AwejEChybPTie8A=w264-h156-n-nu-rw 1x, https://lh3.googleusercontent.com/5E3cNGtS0t4rKlZ1BYBXU93xYwONyYQqIpmY-askDQ9jpTPVb-JH20Gk3wxcMdokGY2ygzjj_crFIy-MYFY-VnekgQVzbSs0Y64AwejEChybPTie8A=w528-h312-n-nu-rw 2x" /> <img alt="" class="picture__image" height="156" loading="lazy" role="presentation" src="https://lh3.googleusercontent.com/5E3cNGtS0t4rKlZ1BYBXU93xYwONyYQqIpmY-askDQ9jpTPVb-JH20Gk3wxcMdokGY2ygzjj_crFIy-MYFY-VnekgQVzbSs0Y64AwejEChybPTie8A=w264-h156-n-nu" width="264"> </picture> <strong class="gdm-header__title">AlphaQubit tackles one of quantum computing’s biggest challenges</strong> <time datetime="2024-11-20" class="glue-label gdm-header__featured-date">20 November 2024</time> <svg aria-hidden="true" class="glue-icon glue-icon--18px gdm-header__featured-icon" role="presentation"> <use href="/static/glue-icons.87e996bc684c.svg#open-in-new"></use> </svg> </a> </li> <li> <a class="glue-header__link gdm-header__featured-item" data-gtm-tag="header-selection" href="https://blog.google/technology/ai/ai-science-forum-2024/" rel="noopener" target="_blank"> <picture class="picture gdm-header__featured-image"> <source type="image/webp" width="264" height="156" srcset="https://lh3.googleusercontent.com/013uzey1mkIgSCsLZ_PieJORMUI5F6yviXI7baiAmkEf8FF1-TC8TMVNY7GY67dejQ8sKtPDJTEbCb_KSaSgdknavAHiqRnd3V1i9fkE4yzBS1R-IA=w264-h156-n-nu-rw 1x, https://lh3.googleusercontent.com/013uzey1mkIgSCsLZ_PieJORMUI5F6yviXI7baiAmkEf8FF1-TC8TMVNY7GY67dejQ8sKtPDJTEbCb_KSaSgdknavAHiqRnd3V1i9fkE4yzBS1R-IA=w528-h312-n-nu-rw 2x" /> <img alt="" class="picture__image" height="156" loading="lazy" role="presentation" src="https://lh3.googleusercontent.com/013uzey1mkIgSCsLZ_PieJORMUI5F6yviXI7baiAmkEf8FF1-TC8TMVNY7GY67dejQ8sKtPDJTEbCb_KSaSgdknavAHiqRnd3V1i9fkE4yzBS1R-IA=w264-h156-n-nu" width="264"> </picture> <strong class="gdm-header__title">The AI for Science Forum: A new era of discovery</strong> <time datetime="2024-11-18" class="glue-label gdm-header__featured-date">18 November 2024</time> <svg aria-hidden="true" class="glue-icon glue-icon--18px gdm-header__featured-icon" role="presentation"> <use href="/static/glue-icons.87e996bc684c.svg#open-in-new"></use> </svg> </a> </li> </ul> </div> </div> </nav> </div> </div> <div class="glue-header__drawer-backdrop gdm-header__backdrop" data-label="Close the navigation drawer"></div> </header> <div class="gdm-header-scrolling"></div> <main id="content" class=""> <h1 class="glue-visually-hidden">Understanding faulty proteins</h1> <div class="glue-page bookmark"> <div class="page-cover glue-grid page-cover--full"><div class="page-cover__content glue-grid__col glue-grid__col--span-12 glue-grid__col--span-12-md page-cover__content--centered page-cover__content--mono"> <h1 class="page-cover__title glue-headline glue-headline--headline-2">AlphaFold: Impact stories</h1> <div class="page-cover__description"><p data-block-key="guqo0">Scientists are using AlphaFold to accelerate research in nearly every field of biology.</p></div> </div> <picture class="picture page-cover__media page-cover__image glue-grid__col glue-grid__col--span-12 glue-grid__col--span-12-md"> <source media="(min-width: 1440px)" type="image/webp" width="1920" height="1200" srcset="https://lh3.googleusercontent.com/sR8osmIQgoZlOfgnA9KD_0rH2X8ccD3tBhyIxK05IQqn3JeiFKnqOQbJ6tamjUbX08Cbk8DZlh3gVC4sGqpL1foOSlzQ_wvc_0oOFHbvxQCizfLsMQ=w1920-h1200-n-nu-rw 1x, https://lh3.googleusercontent.com/sR8osmIQgoZlOfgnA9KD_0rH2X8ccD3tBhyIxK05IQqn3JeiFKnqOQbJ6tamjUbX08Cbk8DZlh3gVC4sGqpL1foOSlzQ_wvc_0oOFHbvxQCizfLsMQ=w3840-h2400-n-nu-rw 2x" /><source media="(min-width: 1024px)" type="image/webp" width="1440" height="1200" srcset="https://lh3.googleusercontent.com/sR8osmIQgoZlOfgnA9KD_0rH2X8ccD3tBhyIxK05IQqn3JeiFKnqOQbJ6tamjUbX08Cbk8DZlh3gVC4sGqpL1foOSlzQ_wvc_0oOFHbvxQCizfLsMQ=w1440-h1200-n-nu-rw 1x, https://lh3.googleusercontent.com/sR8osmIQgoZlOfgnA9KD_0rH2X8ccD3tBhyIxK05IQqn3JeiFKnqOQbJ6tamjUbX08Cbk8DZlh3gVC4sGqpL1foOSlzQ_wvc_0oOFHbvxQCizfLsMQ=w2880-h2400-n-nu-rw 2x" /><source media="(min-width: 600px)" type="image/webp" width="1024" height="1200" srcset="https://lh3.googleusercontent.com/sR8osmIQgoZlOfgnA9KD_0rH2X8ccD3tBhyIxK05IQqn3JeiFKnqOQbJ6tamjUbX08Cbk8DZlh3gVC4sGqpL1foOSlzQ_wvc_0oOFHbvxQCizfLsMQ=w1024-h1200-n-nu-rw 1x, https://lh3.googleusercontent.com/sR8osmIQgoZlOfgnA9KD_0rH2X8ccD3tBhyIxK05IQqn3JeiFKnqOQbJ6tamjUbX08Cbk8DZlh3gVC4sGqpL1foOSlzQ_wvc_0oOFHbvxQCizfLsMQ=w2048-h2400-n-nu-rw 2x" /><source type="image/webp" width="600" height="1200" srcset="https://lh3.googleusercontent.com/sR8osmIQgoZlOfgnA9KD_0rH2X8ccD3tBhyIxK05IQqn3JeiFKnqOQbJ6tamjUbX08Cbk8DZlh3gVC4sGqpL1foOSlzQ_wvc_0oOFHbvxQCizfLsMQ=w600-h1200-n-nu-rw 1x, https://lh3.googleusercontent.com/sR8osmIQgoZlOfgnA9KD_0rH2X8ccD3tBhyIxK05IQqn3JeiFKnqOQbJ6tamjUbX08Cbk8DZlh3gVC4sGqpL1foOSlzQ_wvc_0oOFHbvxQCizfLsMQ=w1200-h2400-n-nu-rw 2x" /> <img alt="" class="picture__image" height="1200" role="presentation" src="https://lh3.googleusercontent.com/sR8osmIQgoZlOfgnA9KD_0rH2X8ccD3tBhyIxK05IQqn3JeiFKnqOQbJ6tamjUbX08Cbk8DZlh3gVC4sGqpL1foOSlzQ_wvc_0oOFHbvxQCizfLsMQ=w1440-h1200-n-nu" width="1440"> </picture> </div> <gemini-large-text class="gemini-large-text"> <div class="gemini-large-text__headline glue-headline glue-headline--headline-2"> <p data-block-key="rt4vk">Over <strong>2 million researchers</strong> in over <strong>190 countries</strong> are using the AlphaFold Protein Structure Database to inform their research.</p> </div></gemini-large-text> <aside class="button-group button-group--centered"> <ul class="button-group__buttons glue-no-bullet"> <li> <gemini-button data-in-view> <a class="button glue-button glue-button--high-emphasis glue-button--icon-right" data-gtm-tag="cta-selection" href="https://alphafold.ebi.ac.uk/" rel="noopener" target="_blank"> <span class="button__text">Explore the database</span> <svg aria-hidden="true" class="glue-icon button__icon" role="presentation"> <use href="/static/glue-icons.87e996bc684c.svg#open-in-new"></use> </svg> </a> </gemini-button> </li> </ul> </aside> <section class="gemini-card-group"> <ul class="glue-grid glue-no-bullet gemini-card-group__grid cards" style="--span--md: 6; --offset--md: 3;"> <li class="glue-grid__col glue-grid__col--span-6-md glue-grid__col--span-4-lg glue-grid__col--span-4 "> <div class="glue-card card card--feature"><div class="glue-card__inner"> <picture class="picture glue-card__asset"> <source media="(min-width: 1440px)" type="image/webp" width="416" height="234" srcset="https://lh3.googleusercontent.com/aErKRLDTdGQEQjTv6zKO_cguD7UjGKiK7Sxx4JlOAodSbshvBPC_-yec5JqwpAhkCVe0zp--I7LfkmG8nbqXKZSfdrWGT_VxmwmCO7wvLs9cR7ZQog=w416-rw 1x, https://lh3.googleusercontent.com/aErKRLDTdGQEQjTv6zKO_cguD7UjGKiK7Sxx4JlOAodSbshvBPC_-yec5JqwpAhkCVe0zp--I7LfkmG8nbqXKZSfdrWGT_VxmwmCO7wvLs9cR7ZQog=w832-rw 2x" /><source media="(min-width: 1024px)" type="image/webp" width="415" height="233" srcset="https://lh3.googleusercontent.com/aErKRLDTdGQEQjTv6zKO_cguD7UjGKiK7Sxx4JlOAodSbshvBPC_-yec5JqwpAhkCVe0zp--I7LfkmG8nbqXKZSfdrWGT_VxmwmCO7wvLs9cR7ZQog=w415-rw 1x, https://lh3.googleusercontent.com/aErKRLDTdGQEQjTv6zKO_cguD7UjGKiK7Sxx4JlOAodSbshvBPC_-yec5JqwpAhkCVe0zp--I7LfkmG8nbqXKZSfdrWGT_VxmwmCO7wvLs9cR7ZQog=w830-rw 2x" /><source media="(min-width: 600px)" type="image/webp" width="460" height="258" srcset="https://lh3.googleusercontent.com/aErKRLDTdGQEQjTv6zKO_cguD7UjGKiK7Sxx4JlOAodSbshvBPC_-yec5JqwpAhkCVe0zp--I7LfkmG8nbqXKZSfdrWGT_VxmwmCO7wvLs9cR7ZQog=w460-rw 1x, https://lh3.googleusercontent.com/aErKRLDTdGQEQjTv6zKO_cguD7UjGKiK7Sxx4JlOAodSbshvBPC_-yec5JqwpAhkCVe0zp--I7LfkmG8nbqXKZSfdrWGT_VxmwmCO7wvLs9cR7ZQog=w920-rw 2x" /><source type="image/webp" width="500" height="281" srcset="https://lh3.googleusercontent.com/aErKRLDTdGQEQjTv6zKO_cguD7UjGKiK7Sxx4JlOAodSbshvBPC_-yec5JqwpAhkCVe0zp--I7LfkmG8nbqXKZSfdrWGT_VxmwmCO7wvLs9cR7ZQog=w500-rw 1x, https://lh3.googleusercontent.com/aErKRLDTdGQEQjTv6zKO_cguD7UjGKiK7Sxx4JlOAodSbshvBPC_-yec5JqwpAhkCVe0zp--I7LfkmG8nbqXKZSfdrWGT_VxmwmCO7wvLs9cR7ZQog=w1000-rw 2x" /> <img alt="" class="picture__image" height="233" loading="lazy" role="presentation" src="https://lh3.googleusercontent.com/aErKRLDTdGQEQjTv6zKO_cguD7UjGKiK7Sxx4JlOAodSbshvBPC_-yec5JqwpAhkCVe0zp--I7LfkmG8nbqXKZSfdrWGT_VxmwmCO7wvLs9cR7ZQog=w415" width="415"> </picture> <div class="glue-card__content"><p class="glue-headline glue-headline--headline-5">Up to 1 billion</p><div class="glue-card__description"><p data-block-key="cujx4">Research years saved by AlphaFold database structures</p></div></div></div></div> </li> <li class="glue-grid__col glue-grid__col--span-6-md glue-grid__col--span-4-lg glue-grid__col--span-4 "> <div class="glue-card card card--feature"><div class="glue-card__inner"> <picture class="picture glue-card__asset"> <source media="(min-width: 1440px)" type="image/webp" width="416" height="234" srcset="https://lh3.googleusercontent.com/FeYAd7falnIaDxaTxI0lzIARHKjWhL6oVMINoh14LJF9Eue-NgntV4IAVpfio9t4u2CRynVw9ZByCdzGklTfuahCALOk50j04qtEytkhst4ls1JSHKk=w416-rw 1x, https://lh3.googleusercontent.com/FeYAd7falnIaDxaTxI0lzIARHKjWhL6oVMINoh14LJF9Eue-NgntV4IAVpfio9t4u2CRynVw9ZByCdzGklTfuahCALOk50j04qtEytkhst4ls1JSHKk=w832-rw 2x" /><source media="(min-width: 1024px)" type="image/webp" width="415" height="233" srcset="https://lh3.googleusercontent.com/FeYAd7falnIaDxaTxI0lzIARHKjWhL6oVMINoh14LJF9Eue-NgntV4IAVpfio9t4u2CRynVw9ZByCdzGklTfuahCALOk50j04qtEytkhst4ls1JSHKk=w415-rw 1x, https://lh3.googleusercontent.com/FeYAd7falnIaDxaTxI0lzIARHKjWhL6oVMINoh14LJF9Eue-NgntV4IAVpfio9t4u2CRynVw9ZByCdzGklTfuahCALOk50j04qtEytkhst4ls1JSHKk=w830-rw 2x" /><source media="(min-width: 600px)" type="image/webp" width="460" height="258" srcset="https://lh3.googleusercontent.com/FeYAd7falnIaDxaTxI0lzIARHKjWhL6oVMINoh14LJF9Eue-NgntV4IAVpfio9t4u2CRynVw9ZByCdzGklTfuahCALOk50j04qtEytkhst4ls1JSHKk=w460-rw 1x, https://lh3.googleusercontent.com/FeYAd7falnIaDxaTxI0lzIARHKjWhL6oVMINoh14LJF9Eue-NgntV4IAVpfio9t4u2CRynVw9ZByCdzGklTfuahCALOk50j04qtEytkhst4ls1JSHKk=w920-rw 2x" /><source type="image/webp" width="500" height="281" srcset="https://lh3.googleusercontent.com/FeYAd7falnIaDxaTxI0lzIARHKjWhL6oVMINoh14LJF9Eue-NgntV4IAVpfio9t4u2CRynVw9ZByCdzGklTfuahCALOk50j04qtEytkhst4ls1JSHKk=w500-rw 1x, https://lh3.googleusercontent.com/FeYAd7falnIaDxaTxI0lzIARHKjWhL6oVMINoh14LJF9Eue-NgntV4IAVpfio9t4u2CRynVw9ZByCdzGklTfuahCALOk50j04qtEytkhst4ls1JSHKk=w1000-rw 2x" /> <img alt="" class="picture__image" height="233" loading="lazy" role="presentation" src="https://lh3.googleusercontent.com/FeYAd7falnIaDxaTxI0lzIARHKjWhL6oVMINoh14LJF9Eue-NgntV4IAVpfio9t4u2CRynVw9ZByCdzGklTfuahCALOk50j04qtEytkhst4ls1JSHKk=w415" width="415"> </picture> <div class="glue-card__content"><p class="glue-headline glue-headline--headline-5">Over 600,000</p><div class="glue-card__description"><p data-block-key="5xa31">Users in low and middle income countries</p></div></div></div></div> </li> <li class="glue-grid__col glue-grid__col--span-6-md glue-grid__col--span-4-lg glue-grid__col--span-4 cards--offset-md"> <div class="glue-card card card--feature"><div class="glue-card__inner"> <picture class="picture glue-card__asset"> <source media="(min-width: 1440px)" type="image/webp" width="416" height="234" srcset="https://lh3.googleusercontent.com/HSyd7TNIr9ren5RbcvLKiMmg4l9PS3KEWQofLpcn2uBP5Dg4N_ZONGAvlt1VPMn5VMGwZCcan6G3wHfQygFMChUnsGqfQWpaCw4C_x3qmf7WTH3g=w416-rw 1x, https://lh3.googleusercontent.com/HSyd7TNIr9ren5RbcvLKiMmg4l9PS3KEWQofLpcn2uBP5Dg4N_ZONGAvlt1VPMn5VMGwZCcan6G3wHfQygFMChUnsGqfQWpaCw4C_x3qmf7WTH3g=w832-rw 2x" /><source media="(min-width: 1024px)" type="image/webp" width="415" height="233" srcset="https://lh3.googleusercontent.com/HSyd7TNIr9ren5RbcvLKiMmg4l9PS3KEWQofLpcn2uBP5Dg4N_ZONGAvlt1VPMn5VMGwZCcan6G3wHfQygFMChUnsGqfQWpaCw4C_x3qmf7WTH3g=w415-rw 1x, https://lh3.googleusercontent.com/HSyd7TNIr9ren5RbcvLKiMmg4l9PS3KEWQofLpcn2uBP5Dg4N_ZONGAvlt1VPMn5VMGwZCcan6G3wHfQygFMChUnsGqfQWpaCw4C_x3qmf7WTH3g=w830-rw 2x" /><source media="(min-width: 600px)" type="image/webp" width="460" height="258" srcset="https://lh3.googleusercontent.com/HSyd7TNIr9ren5RbcvLKiMmg4l9PS3KEWQofLpcn2uBP5Dg4N_ZONGAvlt1VPMn5VMGwZCcan6G3wHfQygFMChUnsGqfQWpaCw4C_x3qmf7WTH3g=w460-rw 1x, https://lh3.googleusercontent.com/HSyd7TNIr9ren5RbcvLKiMmg4l9PS3KEWQofLpcn2uBP5Dg4N_ZONGAvlt1VPMn5VMGwZCcan6G3wHfQygFMChUnsGqfQWpaCw4C_x3qmf7WTH3g=w920-rw 2x" /><source type="image/webp" width="500" height="281" srcset="https://lh3.googleusercontent.com/HSyd7TNIr9ren5RbcvLKiMmg4l9PS3KEWQofLpcn2uBP5Dg4N_ZONGAvlt1VPMn5VMGwZCcan6G3wHfQygFMChUnsGqfQWpaCw4C_x3qmf7WTH3g=w500-rw 1x, https://lh3.googleusercontent.com/HSyd7TNIr9ren5RbcvLKiMmg4l9PS3KEWQofLpcn2uBP5Dg4N_ZONGAvlt1VPMn5VMGwZCcan6G3wHfQygFMChUnsGqfQWpaCw4C_x3qmf7WTH3g=w1000-rw 2x" /> <img alt="" class="picture__image" height="233" loading="lazy" role="presentation" src="https://lh3.googleusercontent.com/HSyd7TNIr9ren5RbcvLKiMmg4l9PS3KEWQofLpcn2uBP5Dg4N_ZONGAvlt1VPMn5VMGwZCcan6G3wHfQygFMChUnsGqfQWpaCw4C_x3qmf7WTH3g=w415" width="415"> </picture> <div class="glue-card__content"><p class="glue-headline glue-headline--headline-5">21%</p><div class="glue-card__description"><p data-block-key="5xa31">Of papers citing AlphaFold are related to the study of disease</p></div></div></div></div> </li> </ul> </section> <div class="section-title"> <h2 class="glue-headline glue-headline--headline-2 section-title__title">Explore some of their stories</h2> <div class="glue-body--large section-title__description"><p data-block-key="b1o6t">From building more effective malaria vaccines to breaking down single-use plastics, AlphaFold is helping scientists accelerate research in nearly every field of biology.</p></div> </div> <ul class="glue-grid glue-cards cards cards--compact"><li class="glue-grid__col glue-grid__col--span-12 glue-grid__col--span-6-lg glue-grid__col--span-4-xl"> <a class="glue-card card glue-card--list" data-gtm-tag="card-selection" href="/technologies/alphafold/impact-stories/accelerating-the-fight-against-malaria/" data-gdm-modal-trigger=""> <div class="glue-card__inner"> <picture class="picture glue-card__asset"> <source type="image/webp" width="132" height="132" srcset="https://lh3.googleusercontent.com/M11CUSEeJRK9gGvzCRgAtWaQreiSSDhvTJjXq7z4BSXUopRRbdqidVa44nhFaE7HahafHWUCBdz9IpatOzFBPsHOXv1sevYThHthRjpsBo06ug2qEw=w132-h132-n-nu-rw 1x, https://lh3.googleusercontent.com/M11CUSEeJRK9gGvzCRgAtWaQreiSSDhvTJjXq7z4BSXUopRRbdqidVa44nhFaE7HahafHWUCBdz9IpatOzFBPsHOXv1sevYThHthRjpsBo06ug2qEw=w264-h264-n-nu-rw 2x" /> <img alt="" class="picture__image" height="132" loading="lazy" role="presentation" src="https://lh3.googleusercontent.com/M11CUSEeJRK9gGvzCRgAtWaQreiSSDhvTJjXq7z4BSXUopRRbdqidVa44nhFaE7HahafHWUCBdz9IpatOzFBPsHOXv1sevYThHthRjpsBo06ug2qEw=w132-h132-n-nu" width="132"> </picture> <div class="glue-card__content"> <p class="glue-label">Case study</p> <p class="glue-headline glue-headline--headline-6">Accelerating the fight against malaria</p> </div> <div class="glue-card__cta"> <span class="glue-button glue-button--low-emphasis"> Learn more </span> </div> </div> <gemini-border-gradient class="gemini-border card__gradient"> <div class="gemini-border__sub-border"></div> </gemini-border-gradient> </a> </li><li class="glue-grid__col glue-grid__col--span-12 glue-grid__col--span-6-lg glue-grid__col--span-4-xl"> <a class="glue-card card glue-card--list" data-gtm-tag="card-selection" href="/technologies/alphafold/impact-stories/using-ai-to-spot-osteoporosis-earlier/" data-gdm-modal-trigger=""> <div class="glue-card__inner"> <picture class="picture glue-card__asset"> <source type="image/webp" width="132" height="132" srcset="https://lh3.googleusercontent.com/7M1ZATSmYi1uqzcKfNnPLUWw5tDgl4hL8NFKPwnPDN-IsrSD4GwMzbkedS5JVfvZvVfEu9FcCjK0W_DIMI6AyHmCRQ2UMJ1P3l1g8Qv76HuJnqxb7Fo=w132-h132-n-nu-rw 1x, https://lh3.googleusercontent.com/7M1ZATSmYi1uqzcKfNnPLUWw5tDgl4hL8NFKPwnPDN-IsrSD4GwMzbkedS5JVfvZvVfEu9FcCjK0W_DIMI6AyHmCRQ2UMJ1P3l1g8Qv76HuJnqxb7Fo=w264-h264-n-nu-rw 2x" /> <img alt="" class="picture__image" height="132" loading="lazy" role="presentation" src="https://lh3.googleusercontent.com/7M1ZATSmYi1uqzcKfNnPLUWw5tDgl4hL8NFKPwnPDN-IsrSD4GwMzbkedS5JVfvZvVfEu9FcCjK0W_DIMI6AyHmCRQ2UMJ1P3l1g8Qv76HuJnqxb7Fo=w132-h132-n-nu" width="132"> </picture> <div class="glue-card__content"> <p class="glue-label">Case study</p> <p class="glue-headline glue-headline--headline-6">Using AI to spot osteoporosis earlier</p> </div> <div class="glue-card__cta"> <span class="glue-button glue-button--low-emphasis"> Learn more </span> </div> </div> <gemini-border-gradient class="gemini-border card__gradient"> <div class="gemini-border__sub-border"></div> </gemini-border-gradient> </a> </li><li class="glue-grid__col glue-grid__col--span-12 glue-grid__col--span-6-lg glue-grid__col--span-4-xl"> <a class="glue-card card glue-card--list" data-gtm-tag="card-selection" href="/technologies/alphafold/impact-stories/understanding-faulty-proteins/" data-gdm-modal-trigger=""> <div class="glue-card__inner"> <picture class="picture glue-card__asset"> <source type="image/webp" width="132" height="132" srcset="https://lh3.googleusercontent.com/ddB3s-FVlzpqyAQSEgM3KcDY3JezaeFvWXx6Mm7y8U_BGlCvD-WqrtZpkTUhZ68_aGa_e2P31vxCmmAU0m0U-qMnEFC2pWW3AqwZ03chxcbNR3glTkg=w132-h132-n-nu-rw 1x, https://lh3.googleusercontent.com/ddB3s-FVlzpqyAQSEgM3KcDY3JezaeFvWXx6Mm7y8U_BGlCvD-WqrtZpkTUhZ68_aGa_e2P31vxCmmAU0m0U-qMnEFC2pWW3AqwZ03chxcbNR3glTkg=w264-h264-n-nu-rw 2x" /> <img alt="" class="picture__image" height="132" loading="lazy" role="presentation" src="https://lh3.googleusercontent.com/ddB3s-FVlzpqyAQSEgM3KcDY3JezaeFvWXx6Mm7y8U_BGlCvD-WqrtZpkTUhZ68_aGa_e2P31vxCmmAU0m0U-qMnEFC2pWW3AqwZ03chxcbNR3glTkg=w132-h132-n-nu" width="132"> </picture> <div class="glue-card__content"> <p class="glue-label">Case study</p> <p class="glue-headline glue-headline--headline-6">Understanding faulty proteins</p> </div> <div class="glue-card__cta"> <span class="glue-button glue-button--low-emphasis"> Learn more </span> </div> </div> <gemini-border-gradient class="gemini-border card__gradient"> <div class="gemini-border__sub-border"></div> </gemini-border-gradient> </a> </li><li class="glue-grid__col glue-grid__col--span-12 glue-grid__col--span-6-lg glue-grid__col--span-4-xl"> <a class="glue-card card glue-card--list" data-gtm-tag="card-selection" href="/technologies/alphafold/impact-stories/racing-against-drug-resistant-bacteria/" data-gdm-modal-trigger=""> <div class="glue-card__inner"> <picture class="picture glue-card__asset"> <source type="image/webp" width="132" height="132" srcset="https://lh3.googleusercontent.com/o-cNbHGnghsGqnHjj2Kfn_X6EUxKLoOjFz5de3K0uPtMNnEbj7buFFu4KDb4w5kszRShKgekzR_stT66YWnffXkCNOscPmH0JPnE9snSvcaLyJYH3Q=w132-h132-n-nu-rw 1x, https://lh3.googleusercontent.com/o-cNbHGnghsGqnHjj2Kfn_X6EUxKLoOjFz5de3K0uPtMNnEbj7buFFu4KDb4w5kszRShKgekzR_stT66YWnffXkCNOscPmH0JPnE9snSvcaLyJYH3Q=w264-h264-n-nu-rw 2x" /> <img alt="" class="picture__image" height="132" loading="lazy" role="presentation" src="https://lh3.googleusercontent.com/o-cNbHGnghsGqnHjj2Kfn_X6EUxKLoOjFz5de3K0uPtMNnEbj7buFFu4KDb4w5kszRShKgekzR_stT66YWnffXkCNOscPmH0JPnE9snSvcaLyJYH3Q=w132-h132-n-nu" width="132"> </picture> <div class="glue-card__content"> <p class="glue-label">Case study</p> <p class="glue-headline glue-headline--headline-6">Racing against drug-resistant bacteria</p> </div> <div class="glue-card__cta"> <span class="glue-button glue-button--low-emphasis"> Learn more </span> </div> </div> <gemini-border-gradient class="gemini-border card__gradient"> <div class="gemini-border__sub-border"></div> </gemini-border-gradient> </a> </li><li class="glue-grid__col glue-grid__col--span-12 glue-grid__col--span-6-lg glue-grid__col--span-4-xl"> <a class="glue-card card glue-card--list" data-gtm-tag="card-selection" href="/technologies/alphafold/impact-stories/solving-an-extinction-mystery/" data-gdm-modal-trigger=""> <div class="glue-card__inner"> <picture class="picture glue-card__asset"> <source type="image/webp" width="132" height="132" srcset="https://lh3.googleusercontent.com/QDnEDih_GC2i8jvM0Ko7DZU2tBCWYkbwX9TfggaLzCIKt1LC1DdAhaUKuXMnpjt7z84oSBCH4-lRaTkMZHlYo7cX2GCOzoZxDIwzLw0P6JMBrJ6L4fs=w132-h132-n-nu-rw 1x, https://lh3.googleusercontent.com/QDnEDih_GC2i8jvM0Ko7DZU2tBCWYkbwX9TfggaLzCIKt1LC1DdAhaUKuXMnpjt7z84oSBCH4-lRaTkMZHlYo7cX2GCOzoZxDIwzLw0P6JMBrJ6L4fs=w264-h264-n-nu-rw 2x" /> <img alt="" class="picture__image" height="132" loading="lazy" role="presentation" src="https://lh3.googleusercontent.com/QDnEDih_GC2i8jvM0Ko7DZU2tBCWYkbwX9TfggaLzCIKt1LC1DdAhaUKuXMnpjt7z84oSBCH4-lRaTkMZHlYo7cX2GCOzoZxDIwzLw0P6JMBrJ6L4fs=w132-h132-n-nu" width="132"> </picture> <div class="glue-card__content"> <p class="glue-label">Case study</p> <p class="glue-headline glue-headline--headline-6">Solving an extinction mystery</p> </div> <div class="glue-card__cta"> <span class="glue-button glue-button--low-emphasis"> Learn more </span> </div> </div> <gemini-border-gradient class="gemini-border card__gradient"> <div class="gemini-border__sub-border"></div> </gemini-border-gradient> </a> </li><li class="glue-grid__col glue-grid__col--span-12 glue-grid__col--span-6-lg glue-grid__col--span-4-xl"> <a class="glue-card card glue-card--list" data-gtm-tag="card-selection" href="/technologies/alphafold/impact-stories/paving-the-way-for-potential-parkinsons-treatments/" data-gdm-modal-trigger=""> <div class="glue-card__inner"> <picture class="picture glue-card__asset"> <source type="image/webp" width="132" height="132" srcset="https://lh3.googleusercontent.com/vjIDTG2gRjKo7Nnv9Jk7jLCpNqT7zIa9BW88Ps-OC8A0LxoBRWfgeNhMhro34xaJKAbDTTfZJgciPYfnR3XvRQLMLJboXxQfuqmeVTRxaVkg5q55oA=w132-h132-n-nu-rw 1x, https://lh3.googleusercontent.com/vjIDTG2gRjKo7Nnv9Jk7jLCpNqT7zIa9BW88Ps-OC8A0LxoBRWfgeNhMhro34xaJKAbDTTfZJgciPYfnR3XvRQLMLJboXxQfuqmeVTRxaVkg5q55oA=w264-h264-n-nu-rw 2x" /> <img alt="" class="picture__image" height="132" loading="lazy" role="presentation" src="https://lh3.googleusercontent.com/vjIDTG2gRjKo7Nnv9Jk7jLCpNqT7zIa9BW88Ps-OC8A0LxoBRWfgeNhMhro34xaJKAbDTTfZJgciPYfnR3XvRQLMLJboXxQfuqmeVTRxaVkg5q55oA=w132-h132-n-nu" width="132"> </picture> <div class="glue-card__content"> <p class="glue-label">Case study</p> <p class="glue-headline glue-headline--headline-6">Paving the way for potential Parkinson’s treatments</p> </div> <div class="glue-card__cta"> <span class="glue-button glue-button--low-emphasis"> Learn more </span> </div> </div> <gemini-border-gradient class="gemini-border card__gradient"> <div class="gemini-border__sub-border"></div> </gemini-border-gradient> </a> </li></ul> <div class="quote-breaker quote-breaker--grey050"> <picture class="picture quote-breaker__background-image"> <source media="(min-width: 1024px)" type="image/webp" width="1296" height="650" srcset="https://lh3.googleusercontent.com/w8MrOg5Yzd-D6197oLm1WSmUfLP25cGs8HDyPg4Qec68DVeiCVZ4Ijqlmq-DO0ymYL_KZScq6IBNXkecjbWPjzuRie02c21qbmrcM1r4XrqLR8Py=w1296-rw 1x, https://lh3.googleusercontent.com/w8MrOg5Yzd-D6197oLm1WSmUfLP25cGs8HDyPg4Qec68DVeiCVZ4Ijqlmq-DO0ymYL_KZScq6IBNXkecjbWPjzuRie02c21qbmrcM1r4XrqLR8Py=w2592-rw 2x" /><source media="(min-width: 600px)" type="image/webp" width="928" height="465" srcset="https://lh3.googleusercontent.com/w8MrOg5Yzd-D6197oLm1WSmUfLP25cGs8HDyPg4Qec68DVeiCVZ4Ijqlmq-DO0ymYL_KZScq6IBNXkecjbWPjzuRie02c21qbmrcM1r4XrqLR8Py=w928-rw 1x, https://lh3.googleusercontent.com/w8MrOg5Yzd-D6197oLm1WSmUfLP25cGs8HDyPg4Qec68DVeiCVZ4Ijqlmq-DO0ymYL_KZScq6IBNXkecjbWPjzuRie02c21qbmrcM1r4XrqLR8Py=w1856-rw 2x" /><source type="image/webp" width="528" height="264" srcset="https://lh3.googleusercontent.com/w8MrOg5Yzd-D6197oLm1WSmUfLP25cGs8HDyPg4Qec68DVeiCVZ4Ijqlmq-DO0ymYL_KZScq6IBNXkecjbWPjzuRie02c21qbmrcM1r4XrqLR8Py=w528-rw 1x, https://lh3.googleusercontent.com/w8MrOg5Yzd-D6197oLm1WSmUfLP25cGs8HDyPg4Qec68DVeiCVZ4Ijqlmq-DO0ymYL_KZScq6IBNXkecjbWPjzuRie02c21qbmrcM1r4XrqLR8Py=w1056-rw 2x" /> <img alt="" class="picture__image" height="650" loading="lazy" role="presentation" src="https://lh3.googleusercontent.com/w8MrOg5Yzd-D6197oLm1WSmUfLP25cGs8HDyPg4Qec68DVeiCVZ4Ijqlmq-DO0ymYL_KZScq6IBNXkecjbWPjzuRie02c21qbmrcM1r4XrqLR8Py=w1296" width="1296"> </picture> <figure class="quote-breaker__inner"> <blockquote class="quote-breaker__text"><p data-block-key="6t97v">It normally takes four years to identify and characterise one of these small proteins. With the help of AlphaFold we managed 23 in a few months.</p></blockquote><figcaption class="quote-breaker__attribution gdm-rich-text"><p data-block-key="spakd">Professor Renier van der Hoorn<br/>University of Oxford</p></figcaption></figure> </div> <ul class="glue-grid glue-cards cards cards--compact" style="--span--lg: 6; --offset--lg: 3; --span--xl: 4; --offset--xl: 4;"><li class="glue-grid__col glue-grid__col--span-12 glue-grid__col--span-6-lg glue-grid__col--span-4-xl"> <a class="glue-card card glue-card--list" data-gtm-tag="card-selection" href="/technologies/alphafold/impact-stories/solving-one-of-biologys-greatest-puzzles/" data-gdm-modal-trigger=""> <div class="glue-card__inner"> <picture class="picture glue-card__asset"> <source type="image/webp" width="132" height="132" srcset="https://lh3.googleusercontent.com/I_y9JvJrsvG5l9MsolJ8yRgCt_vPEa9yN1qIgfkusRj35Csn8PSc1HRjcHeuoIdMdZrtNlxg3siqF_g5PTENNAeOZH02RygvUNAi1cQqvp8gk6I58MA=w132-h132-n-nu-rw 1x, https://lh3.googleusercontent.com/I_y9JvJrsvG5l9MsolJ8yRgCt_vPEa9yN1qIgfkusRj35Csn8PSc1HRjcHeuoIdMdZrtNlxg3siqF_g5PTENNAeOZH02RygvUNAi1cQqvp8gk6I58MA=w264-h264-n-nu-rw 2x" /> <img alt="" class="picture__image" height="132" loading="lazy" role="presentation" src="https://lh3.googleusercontent.com/I_y9JvJrsvG5l9MsolJ8yRgCt_vPEa9yN1qIgfkusRj35Csn8PSc1HRjcHeuoIdMdZrtNlxg3siqF_g5PTENNAeOZH02RygvUNAi1cQqvp8gk6I58MA=w132-h132-n-nu" width="132"> </picture> <div class="glue-card__content"> <p class="glue-label">Case study</p> <p class="glue-headline glue-headline--headline-6">Solving one of biology’s greatest puzzles</p> </div> <div class="glue-card__cta"> <span class="glue-button glue-button--low-emphasis"> Learn more </span> </div> </div> <gemini-border-gradient class="gemini-border card__gradient"> <div class="gemini-border__sub-border"></div> </gemini-border-gradient> </a> </li><li class="glue-grid__col glue-grid__col--span-12 glue-grid__col--span-6-lg glue-grid__col--span-4-xl"> <a class="glue-card card glue-card--list" data-gtm-tag="card-selection" href="/technologies/alphafold/impact-stories/breaking-down-plastic-pollution/" data-gdm-modal-trigger=""> <div class="glue-card__inner"> <picture class="picture glue-card__asset"> <source type="image/webp" width="132" height="132" srcset="https://lh3.googleusercontent.com/dHGFQO1UjAzhkFiYEeIRj--1E-n_QYS3pfVMrNZu3JH6QzhwokpI4U46TXEs3QLkih43113CNm_NwqjW5mKscKINHAPuEv8yV6ZpQ_gevvQpX-JG7w=w132-h132-n-nu-rw 1x, https://lh3.googleusercontent.com/dHGFQO1UjAzhkFiYEeIRj--1E-n_QYS3pfVMrNZu3JH6QzhwokpI4U46TXEs3QLkih43113CNm_NwqjW5mKscKINHAPuEv8yV6ZpQ_gevvQpX-JG7w=w264-h264-n-nu-rw 2x" /> <img alt="" class="picture__image" height="132" loading="lazy" role="presentation" src="https://lh3.googleusercontent.com/dHGFQO1UjAzhkFiYEeIRj--1E-n_QYS3pfVMrNZu3JH6QzhwokpI4U46TXEs3QLkih43113CNm_NwqjW5mKscKINHAPuEv8yV6ZpQ_gevvQpX-JG7w=w132-h132-n-nu" width="132"> </picture> <div class="glue-card__content"> <p class="glue-label">Case study</p> <p class="glue-headline glue-headline--headline-6">Breaking down plastic pollution</p> </div> <div class="glue-card__cta"> <span class="glue-button glue-button--low-emphasis"> Learn more </span> </div> </div> <gemini-border-gradient class="gemini-border card__gradient"> <div class="gemini-border__sub-border"></div> </gemini-border-gradient> </a> </li><li class="glue-grid__col glue-grid__col--span-12 glue-grid__col--span-6-lg glue-grid__col--span-4-xl"> <a class="glue-card card glue-card--list" data-gtm-tag="card-selection" href="/technologies/alphafold/impact-stories/designing-more-effective-drugs/" data-gdm-modal-trigger=""> <div class="glue-card__inner"> <picture class="picture glue-card__asset"> <source type="image/webp" width="132" height="132" srcset="https://lh3.googleusercontent.com/JOrlAcoko66fipzyXhZIr9PKtJHv_QsGrr6m1TCAOtPKHO5bJ7dEyQd4fRgGpMh57tbnmdAZ7xH4IVAIVICdY6usxzB5xUCXequDjTzDJe3sSzkCdho=w132-h132-n-nu-rw 1x, https://lh3.googleusercontent.com/JOrlAcoko66fipzyXhZIr9PKtJHv_QsGrr6m1TCAOtPKHO5bJ7dEyQd4fRgGpMh57tbnmdAZ7xH4IVAIVICdY6usxzB5xUCXequDjTzDJe3sSzkCdho=w264-h264-n-nu-rw 2x" /> <img alt="" class="picture__image" height="132" loading="lazy" role="presentation" src="https://lh3.googleusercontent.com/JOrlAcoko66fipzyXhZIr9PKtJHv_QsGrr6m1TCAOtPKHO5bJ7dEyQd4fRgGpMh57tbnmdAZ7xH4IVAIVICdY6usxzB5xUCXequDjTzDJe3sSzkCdho=w132-h132-n-nu" width="132"> </picture> <div class="glue-card__content"> <p class="glue-label">Case study</p> <p class="glue-headline glue-headline--headline-6">Designing more effective drugs</p> </div> <div class="glue-card__cta"> <span class="glue-button glue-button--low-emphasis"> Learn more </span> </div> </div> <gemini-border-gradient class="gemini-border card__gradient"> <div class="gemini-border__sub-border"></div> </gemini-border-gradient> </a> </li><li class="glue-grid__col glue-grid__col--span-12 glue-grid__col--span-6-lg glue-grid__col--span-4-xl"> <a class="glue-card card glue-card--list" data-gtm-tag="card-selection" href="/technologies/alphafold/impact-stories/increasing-honeybees-chances-of-survival/" data-gdm-modal-trigger=""> <div class="glue-card__inner"> <picture class="picture glue-card__asset"> <source type="image/webp" width="132" height="132" srcset="https://lh3.googleusercontent.com/f4F6C9atwrYVHSSM6BnBstgT7Lzf_rFPCDwKR6mGr5S2QVj69YFnagK7zHgPrOzac0dXYQHRzCV0PlBM78pWTcWpjWuGmdESDzGwxGT4MxWekBXVNA=w132-h132-n-nu-rw 1x, https://lh3.googleusercontent.com/f4F6C9atwrYVHSSM6BnBstgT7Lzf_rFPCDwKR6mGr5S2QVj69YFnagK7zHgPrOzac0dXYQHRzCV0PlBM78pWTcWpjWuGmdESDzGwxGT4MxWekBXVNA=w264-h264-n-nu-rw 2x" /> <img alt="" class="picture__image" height="132" loading="lazy" role="presentation" src="https://lh3.googleusercontent.com/f4F6C9atwrYVHSSM6BnBstgT7Lzf_rFPCDwKR6mGr5S2QVj69YFnagK7zHgPrOzac0dXYQHRzCV0PlBM78pWTcWpjWuGmdESDzGwxGT4MxWekBXVNA=w132-h132-n-nu" width="132"> </picture> <div class="glue-card__content"> <p class="glue-label">Case study</p> <p class="glue-headline glue-headline--headline-6">Increasing honeybees’ chances of survival</p> </div> <div class="glue-card__cta"> <span class="glue-button glue-button--low-emphasis"> Learn more </span> </div> </div> <gemini-border-gradient class="gemini-border card__gradient"> <div class="gemini-border__sub-border"></div> </gemini-border-gradient> </a> </li><li class="glue-grid__col glue-grid__col--span-12 glue-grid__col--span-6-lg glue-grid__col--span-4-xl"> <a class="glue-card card glue-card--list" data-gtm-tag="card-selection" href="/technologies/alphafold/impact-stories/searching-for-life-changing-medicines/" data-gdm-modal-trigger=""> <div class="glue-card__inner"> <picture class="picture glue-card__asset"> <source type="image/webp" width="132" height="132" srcset="https://lh3.googleusercontent.com/T-Xh-xJk83D0zkaolRvfgrxSiXmiBYTclpc7hJbQHB2i0b6QbuK2lXWZhmlYGGrhVktZ0bU9IWl2QzPlYvV_EqqDEBJt-mE8FjUKgjiDtjvUxvrr=w132-h132-n-nu-rw 1x, https://lh3.googleusercontent.com/T-Xh-xJk83D0zkaolRvfgrxSiXmiBYTclpc7hJbQHB2i0b6QbuK2lXWZhmlYGGrhVktZ0bU9IWl2QzPlYvV_EqqDEBJt-mE8FjUKgjiDtjvUxvrr=w264-h264-n-nu-rw 2x" /> <img alt="" class="picture__image" height="132" loading="lazy" role="presentation" src="https://lh3.googleusercontent.com/T-Xh-xJk83D0zkaolRvfgrxSiXmiBYTclpc7hJbQHB2i0b6QbuK2lXWZhmlYGGrhVktZ0bU9IWl2QzPlYvV_EqqDEBJt-mE8FjUKgjiDtjvUxvrr=w132-h132-n-nu" width="132"> </picture> <div class="glue-card__content"> <p class="glue-label">Case study</p> <p class="glue-headline glue-headline--headline-6">Searching for life-changing medicines</p> </div> <div class="glue-card__cta"> <span class="glue-button glue-button--low-emphasis"> Learn more </span> </div> </div> <gemini-border-gradient class="gemini-border card__gradient"> <div class="gemini-border__sub-border"></div> </gemini-border-gradient> </a> </li><li class="glue-grid__col glue-grid__col--span-12 glue-grid__col--span-6-lg glue-grid__col--span-4-xl"> <a class="glue-card card glue-card--list" data-gtm-tag="card-selection" href="/technologies/alphafold/impact-stories/tracing-proteins-back-to-origins-of-life/" data-gdm-modal-trigger=""> <div class="glue-card__inner"> <picture class="picture glue-card__asset"> <source type="image/webp" width="132" height="132" srcset="https://lh3.googleusercontent.com/6TXa-nCiQWl-HAh9uUoOEEqSCecP7mAsjbyfb823PvMuq-wW56Xv4CNnMlBSXH-ck_JWp1C1d3onjXPc4J656_V2JFvpUJlTXAUyVTCcQRvv6D0i5Q=w132-h132-n-nu-rw 1x, https://lh3.googleusercontent.com/6TXa-nCiQWl-HAh9uUoOEEqSCecP7mAsjbyfb823PvMuq-wW56Xv4CNnMlBSXH-ck_JWp1C1d3onjXPc4J656_V2JFvpUJlTXAUyVTCcQRvv6D0i5Q=w264-h264-n-nu-rw 2x" /> <img alt="" class="picture__image" height="132" loading="lazy" role="presentation" src="https://lh3.googleusercontent.com/6TXa-nCiQWl-HAh9uUoOEEqSCecP7mAsjbyfb823PvMuq-wW56Xv4CNnMlBSXH-ck_JWp1C1d3onjXPc4J656_V2JFvpUJlTXAUyVTCcQRvv6D0i5Q=w132-h132-n-nu" width="132"> </picture> <div class="glue-card__content"> <p class="glue-label">Case study</p> <p class="glue-headline glue-headline--headline-6">Tracing proteins back to origins of life</p> </div> <div class="glue-card__cta"> <span class="glue-button glue-button--low-emphasis"> Learn more </span> </div> </div> <gemini-border-gradient class="gemini-border card__gradient"> <div class="gemini-border__sub-border"></div> </gemini-border-gradient> </a> </li><li class="glue-grid__col glue-grid__col--span-12 glue-grid__col--span-6-lg glue-grid__col--span-4-xl cards--offset-lg cards--offset-xl"> <a class="glue-card card glue-card--list" data-gtm-tag="card-selection" href="/technologies/alphafold/impact-stories/creating-a-protein-structure-database/" data-gdm-modal-trigger=""> <div class="glue-card__inner"> <picture class="picture glue-card__asset"> <source type="image/webp" width="132" height="132" srcset="https://lh3.googleusercontent.com/111sJtd5vYvstSGkv30sCGkYJFhsK_ZeFvugNuMydHEzBt1JIDcJJgPWbdESKFGj5g-CdPw1FrLrsLt8RUMPwPEsxwobWFgWTKALQtG7Rs7zA23RBw=w132-h132-n-nu-rw 1x, https://lh3.googleusercontent.com/111sJtd5vYvstSGkv30sCGkYJFhsK_ZeFvugNuMydHEzBt1JIDcJJgPWbdESKFGj5g-CdPw1FrLrsLt8RUMPwPEsxwobWFgWTKALQtG7Rs7zA23RBw=w264-h264-n-nu-rw 2x" /> <img alt="" class="picture__image" height="132" loading="lazy" role="presentation" src="https://lh3.googleusercontent.com/111sJtd5vYvstSGkv30sCGkYJFhsK_ZeFvugNuMydHEzBt1JIDcJJgPWbdESKFGj5g-CdPw1FrLrsLt8RUMPwPEsxwobWFgWTKALQtG7Rs7zA23RBw=w132-h132-n-nu" width="132"> </picture> <div class="glue-card__content"> <p class="glue-label">Case study</p> <p class="glue-headline glue-headline--headline-6">Creating a protein structure database</p> </div> <div class="glue-card__cta"> <span class="glue-button glue-button--low-emphasis"> Learn more </span> </div> </div> <gemini-border-gradient class="gemini-border card__gradient"> <div class="gemini-border__sub-border"></div> </gemini-border-gradient> </a> </li></ul> <figure class="quote quote--large"> <blockquote class="quote__text"> <div aria-hidden="true" class="quote__icon" role="presentation">“</div> <p data-block-key="6adwn">AlphaFold has allowed us to take our project to the next level, from a fundamental science stage to the preclinical and clinical development stage.</p> </blockquote> <figcaption class="quote__author"><p data-block-key="b6tgn">Professor Matthew Higgins<br/>Biochemist</p></figcaption> </figure> <div class="section-title"> <h2 class="glue-headline glue-headline--headline-2 section-title__title">AlphaFold tools</h2> <div class="glue-body--large section-title__description"><p data-block-key="b1o6t">AlphaFold Database and Server are freely available to the scientific community.</p></div> </div> <div class="gemini-card-group"> <div class="glue-grid gemini-card-group__grid"> <gemini-card class="gemini-card-group__card gemini-card gemini-card--large gemini-card--landscape"> <a class="glue-card card gemini-in-view-element" data-gtm-tag="card-selection" data-in-view="true" href="https://alphafold.ebi.ac.uk/" style="--delay: 0.0s" rel="noopener" target="_blank" > <div class="glue-card__inner"> <picture class="picture glue-card__asset"> <source media="(min-width: 1024px)" type="image/webp" width="650" height="365" srcset="https://lh3.googleusercontent.com/iDeN91R0ry137bPtVdkdtbS014buZHoEsN9vbL6ubUxXIphk-DslCNaRtVV73FhnnyPpnhoNMkAMKJGGPlenyIhySay3esLbv-Z8aqlDLCK4mu3dMg=w650-rw 1x, https://lh3.googleusercontent.com/iDeN91R0ry137bPtVdkdtbS014buZHoEsN9vbL6ubUxXIphk-DslCNaRtVV73FhnnyPpnhoNMkAMKJGGPlenyIhySay3esLbv-Z8aqlDLCK4mu3dMg=w1300-rw 2x" /><source media="(min-width: 600px)" type="image/webp" width="450" height="253" srcset="https://lh3.googleusercontent.com/iDeN91R0ry137bPtVdkdtbS014buZHoEsN9vbL6ubUxXIphk-DslCNaRtVV73FhnnyPpnhoNMkAMKJGGPlenyIhySay3esLbv-Z8aqlDLCK4mu3dMg=w450-rw 1x, https://lh3.googleusercontent.com/iDeN91R0ry137bPtVdkdtbS014buZHoEsN9vbL6ubUxXIphk-DslCNaRtVV73FhnnyPpnhoNMkAMKJGGPlenyIhySay3esLbv-Z8aqlDLCK4mu3dMg=w900-rw 2x" /><source type="image/webp" width="550" height="309" srcset="https://lh3.googleusercontent.com/iDeN91R0ry137bPtVdkdtbS014buZHoEsN9vbL6ubUxXIphk-DslCNaRtVV73FhnnyPpnhoNMkAMKJGGPlenyIhySay3esLbv-Z8aqlDLCK4mu3dMg=w550-rw 1x, https://lh3.googleusercontent.com/iDeN91R0ry137bPtVdkdtbS014buZHoEsN9vbL6ubUxXIphk-DslCNaRtVV73FhnnyPpnhoNMkAMKJGGPlenyIhySay3esLbv-Z8aqlDLCK4mu3dMg=w1100-rw 2x" /> <img alt="" class="picture__image" height="365" loading="lazy" role="presentation" src="https://lh3.googleusercontent.com/iDeN91R0ry137bPtVdkdtbS014buZHoEsN9vbL6ubUxXIphk-DslCNaRtVV73FhnnyPpnhoNMkAMKJGGPlenyIhySay3esLbv-Z8aqlDLCK4mu3dMg=w650" width="650"> </picture> <div class="glue-card__content"> <p class="glue-headline glue-headline--headline-4">AlphaFold Protein Structure Database</p> <p class="glue-card__description glue-body--large">View over 200 million protein structure predictions to support your research.</p> </div> <div class="glue-card__cta glue-card__cta--arrow"> <span class="glue-button glue-button--low-emphasis"> <svg aria-hidden="true" class="glue-icon" role="presentation"> <use href="/static/glue-icons.87e996bc684c.svg#open-in-new"></use> </svg> </span> </div> </div> <gemini-border-gradient class="gemini-border card__gradient"> <div class="gemini-border__sub-border"></div> </gemini-border-gradient> </a> </gemini-card> <gemini-card class="gemini-card-group__card gemini-card gemini-card--large gemini-card--landscape"> <a class="glue-card card gemini-in-view-element" data-gtm-tag="card-selection" data-in-view="true" href="/technologies/alphafold/alphafold-server/" style="--delay: 0.1s" > <div class="glue-card__inner"> <picture class="picture glue-card__asset"> <source media="(min-width: 1024px)" type="image/webp" width="650" height="365" srcset="https://lh3.googleusercontent.com/pQdtvOxBU4Dl69yjzRDZq2XQ8NiwAKtQcXPW9jOnOko_pERLEP4ousormd24DJbDtttdSh09X5OurvEmPMQ8aQzf7Z2jQX7P1YAVEXywhcnMu_1ARw=w650-rw 1x, 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height="365" loading="lazy" role="presentation" src="https://lh3.googleusercontent.com/pQdtvOxBU4Dl69yjzRDZq2XQ8NiwAKtQcXPW9jOnOko_pERLEP4ousormd24DJbDtttdSh09X5OurvEmPMQ8aQzf7Z2jQX7P1YAVEXywhcnMu_1ARw=w650" width="650"> </picture> <div class="glue-card__content"> <p class="glue-headline glue-headline--headline-4">AlphaFold Server</p> <p class="glue-card__description glue-body--large">Predict the structure and interactions of all life’s molecules with unprecedented accuracy.</p> </div> <div class="glue-card__cta glue-card__cta--arrow"> <span class="glue-button glue-button--low-emphasis"> <svg aria-hidden="true" class="glue-icon glue-icon--arrow-forward" role="presentation"> <use href="/static/glue-icons.87e996bc684c.svg#arrow-forward"></use> </svg> </span> </div> </div> <gemini-border-gradient class="gemini-border card__gradient"> <div class="gemini-border__sub-border"></div> </gemini-border-gradient> </a> </gemini-card> </div> </div> <div class="cross-linking glue-grid"> <div 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<div class="gdm-modal__backdrop"></div> <div class="gdm-modal__inner"> <span id="modal-label-understanding-faulty-proteins" class="glue-visually-hidden">Understanding faulty proteins</span> <article id="modal-content-understanding-faulty-proteins" class="gdm-modal__content" tabindex="-1"> <div class="glue-page bookmark"> <figure class="single-media single-media--fullbleed single-media--first"> <div class="single-media__media"> <picture class="picture"> <source media="(min-width: 1440px)" type="image/webp" width="1920" height="1080" srcset="https://lh3.googleusercontent.com/ddB3s-FVlzpqyAQSEgM3KcDY3JezaeFvWXx6Mm7y8U_BGlCvD-WqrtZpkTUhZ68_aGa_e2P31vxCmmAU0m0U-qMnEFC2pWW3AqwZ03chxcbNR3glTkg=w1920-rw 1x, https://lh3.googleusercontent.com/ddB3s-FVlzpqyAQSEgM3KcDY3JezaeFvWXx6Mm7y8U_BGlCvD-WqrtZpkTUhZ68_aGa_e2P31vxCmmAU0m0U-qMnEFC2pWW3AqwZ03chxcbNR3glTkg=w3840-rw 2x" /><source media="(min-width: 1024px)" type="image/webp" width="1440" height="810" srcset="https://lh3.googleusercontent.com/ddB3s-FVlzpqyAQSEgM3KcDY3JezaeFvWXx6Mm7y8U_BGlCvD-WqrtZpkTUhZ68_aGa_e2P31vxCmmAU0m0U-qMnEFC2pWW3AqwZ03chxcbNR3glTkg=w1440-rw 1x, https://lh3.googleusercontent.com/ddB3s-FVlzpqyAQSEgM3KcDY3JezaeFvWXx6Mm7y8U_BGlCvD-WqrtZpkTUhZ68_aGa_e2P31vxCmmAU0m0U-qMnEFC2pWW3AqwZ03chxcbNR3glTkg=w2880-rw 2x" /><source media="(min-width: 600px)" type="image/webp" width="1024" height="576" srcset="https://lh3.googleusercontent.com/ddB3s-FVlzpqyAQSEgM3KcDY3JezaeFvWXx6Mm7y8U_BGlCvD-WqrtZpkTUhZ68_aGa_e2P31vxCmmAU0m0U-qMnEFC2pWW3AqwZ03chxcbNR3glTkg=w1024-rw 1x, https://lh3.googleusercontent.com/ddB3s-FVlzpqyAQSEgM3KcDY3JezaeFvWXx6Mm7y8U_BGlCvD-WqrtZpkTUhZ68_aGa_e2P31vxCmmAU0m0U-qMnEFC2pWW3AqwZ03chxcbNR3glTkg=w2048-rw 2x" /><source type="image/webp" width="600" height="337" srcset="https://lh3.googleusercontent.com/ddB3s-FVlzpqyAQSEgM3KcDY3JezaeFvWXx6Mm7y8U_BGlCvD-WqrtZpkTUhZ68_aGa_e2P31vxCmmAU0m0U-qMnEFC2pWW3AqwZ03chxcbNR3glTkg=w600-rw 1x, https://lh3.googleusercontent.com/ddB3s-FVlzpqyAQSEgM3KcDY3JezaeFvWXx6Mm7y8U_BGlCvD-WqrtZpkTUhZ68_aGa_e2P31vxCmmAU0m0U-qMnEFC2pWW3AqwZ03chxcbNR3glTkg=w1200-rw 2x" /> <img alt="" class="picture__image" height="810" src="https://lh3.googleusercontent.com/ddB3s-FVlzpqyAQSEgM3KcDY3JezaeFvWXx6Mm7y8U_BGlCvD-WqrtZpkTUhZ68_aGa_e2P31vxCmmAU0m0U-qMnEFC2pWW3AqwZ03chxcbNR3glTkg=w1440" width="1440"> </picture> </div> </figure> <div class="modal-title"> <span class="glue-label modal-title__eyebrow">26 September 2022</span> <h1 class="glue-headline glue-headline--headline-4 modal-title__heading">Understanding faulty proteins</h1> <div class="gdm-rich-text"></div> </div> <div class="gdm-rich-text rich-text"> <p data-block-key="fxxvn">One family of human proteins is known as potassium channel tetramerisation domain (KTCD) proteins. When these don’t work properly, they are linked to a wide range of conditions including schizophrenia, leukaemia, and autism.</p><p data-block-key="990d4">Using AlphaFold, researchers have been able to build a new evolutionary family tree based on the shape of these proteins. This could help solve all kinds of mysteries, and one day, lead scientists towards new treatments for a range of health conditions.</p><p data-block-key="e9mqc"><strong>Research credits</strong></p><ul><li data-block-key="24ork">Luigi Vitagliano, Research Director, Institute of Biostructures and Bioimaging in Naples, Italy</li></ul> </div> <aside class="button-group button-group--stacked"> <ul class="button-group__buttons glue-no-bullet"> <li> <gemini-button data-in-view> <a class="button glue-button glue-button--tonal" data-gtm-tag="cta-selection" href="/discover/blog/understanding-the-faulty-proteins-linked-to-cancer-and-autism/"> <span class="button__text">Read more</span> </a> </gemini-button> </li> </ul> </aside> </div> </article> <button class="glue-modal__close-btn gdm-modal__close-btn" aria-label="Close the modal"></button> </div> </div> </div> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} function glueCookieNotificationBarLoaded(){(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-NRDHXJGK');} function setScrollbarWidth() { const element = document.createElement('div'); element.style = "overflow:scroll;position:absolute;visibility:hidden;"; document.body.appendChild(element); const width = element.getBoundingClientRect().width; document.documentElement.style.setProperty('--scrollbar-width', `${width}px`); element.remove(); } window.addEventListener('resize', setScrollbarWidth); setScrollbarWidth(); </script> <script src="https://www.gstatic.com/glue/cookienotificationbar/cookienotificationbar.min.js" data-glue-cookie-notification-bar-category="2A"></script> <script src="https://www.youtube.com/player_api"></script> <script src="/static/main.min.eac5b4e00f7e.js"></script> <script src="/static/gemini.min.0f81ce049fa4.js"></script> </body> </html>

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