CINXE.COM
Sign In
<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Strict//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-strict.dtd"> <html xmlns="http://www.w3.org/1999/xhtml" xml:lang="en" lang="en"> <head> <meta http-equiv="Content-Type" content="text/html; charset=UTF-8" /> <title>Sign In </title> <meta name="googlebot" content="NOODP" /> <meta name="description" content="An international, peer-reviewed genome sciences journal featuring outstanding original research that offers novel insights into the biology of all organisms" /> <link rel="stylesheet" type="text/css" media="all" href="/shared/css/hw-global.css" /> <link rel="stylesheet" type="text/css" media="all" href="/shared/css/standard-designs/design2/main.css" /> <link rel="stylesheet" type="text/css" media="all" href="/publisher/css/hw-cshljnls-global.css" /> <link rel="stylesheet" type="text/css" media="all" href="/local/css/hw-journal-global.css" /> <link rel="stylesheet" type="text/css" media="all" href="/shared/css/hw-citation-2.0-hacks.css" /> <link rel="stylesheet" type="text/css" media="print" href="/shared/css/hw-print.css" /> <link rel="stylesheet" type="text/css" media="print" href="/publisher/css/hw-cshljnls-print.css" /> <link rel="stylesheet" type="text/css" media="all" href="/shared/css/hw-page-login.css" /> <link rel="stylesheet" type="text/css" media="all" href="/shared/css/standard-designs/design2/login-page.css" /> <link rel="stylesheet" type="text/css" media="all" href="/publisher/css/hw-cshljnls-page-login.css" /> <link rel="stylesheet" type="text/css" media="all" href="/site/misc/custom-global.css" /><script type="text/javascript" id="session-d11691419e1">var callbackToken='515F3F88F86CA7A';</script><script type="text/javascript" src="/shared/js/jquery-min.js"></script><script type="text/javascript" src="/shared/js/fingerprint.js"></script><script type="text/javascript" src="/shared/js/hw-shared.js"></script><script type="text/javascript" src="/shared/js/design/hw-design1.js"></script><script type="text/javascript" src="/publisher/js/cshl-shared.js"></script><script type="text/javascript" async="async" src="https://scholar.google.com/scholar_js/casa.js"></script><script type="text/javascript" src="/site/misc/custom-global.js"></script></head> <body> <div class="hw-gen-page pagetype-content" id="pageid-login"> <div id="header"> <a href="http://www.cshlpress.com" rel="external-nw"><img src="/local/img/society_logo.gif" width="74" height="83" alt="Publisher Logo" id="main-logo" /></a><a href="/"><img title="Genome Research" alt="Genome Research" width="313" height="83" src="/local/img/journal_logo_standalone.gif" /></a> <p id="skip-link"> <a href="#content-block">Skip to main page content</a> </p> <ul class="button-list header-buttons"> <li class="first"><a href="/" title="HOME"><span>HOME</span></a></li> <li><a href="/site/misc/about.xhtml" title="ABOUT"><span>ABOUT</span></a></li> <li><a href="/content/by/year" title="ARCHIVE"><span>ARCHIVE</span></a></li> <li><a href="http://submit.genome.org/" title="SUBMIT"><span>SUBMIT</span></a></li> <li><a href="/site/subscriptions/" title="SUBSCRIBE"><span>SUBSCRIBE</span></a></li> <li><a href="/site/misc/adinfo.xhtml" title="ADVERTISE"><span>ADVERTISE</span></a></li> <li><a href="/site/misc/ifora.xhtml" title="AUTHOR INFO"><span>AUTHOR INFO</span></a></li> <li><a href="/feedback" title="CONTACT"><span>CONTACT</span></a></li> <li class="last"><a href="/help/" title="HELP"><span>HELP</span></a></li> </ul> <div class="header-qs"> <form class="searchbox" action="/search" method="get"> <div> <label for="header-qs-input" id="header-qs-search-label">Search for Keyword:</label> <input value="" title="Search Genome Research" type="text" name="fulltext" id="header-qs-input" /><input type="hidden" name="submit" value="yes" /><label for="header-qs-search" id="header-qs-search-label">GO</label><input value="GO" alt="Link: Go" type="image" id="header-qs-search-go" src="/shared/img/standard-design/design2/go.gif" /> </div> <div class="adv-search-link"><a href="/search">Advanced Search</a></div> </form> </div> <div class="header-ac-elements"> <div class="inst-branding"> </div> <div id="authstring" class="suppress-header-login"> </div> <div id="hdr-login" class="suppress-header-login"></div> </div> <div class="banner-ads"> <ul> <li><a href="/cgi/adclick/?ad=57883&adclick=true&url=https%3A%2F%2Fprograms.pacb.com%2Fl%2F1652%2F2024-10-14%2F44v4m7" target="_blank"><img class="adborder0" title="PacBio" src="//genome.cshlp.org/adsystem/graphics/45268010153785954/genome/PacBio%20LB%20Accuracy.jpg?ad=57883&adview=true" alt="PacBio" /></a></li> </ul> </div> <div class="bar"> <div class="bar-inner"></div> </div> </div><img src="/shared/img/pages/login/login_hit_hidden.gif?timestamp=2024-11-23T12:58:32.125-08:00" id="hw-login-tracking-gif" width="2" height="2" alt=" " /><div id="content-block"> <div id="hw-login-msg-box"> <div id="hw-login-msg-box-text"> <div> <span> <strong xmlns="">This item requires a subscription to Genome Research. </strong> </span> </div> </div> </div> <div id="hw-login-item-group"> <div id="hw-login-content-item-group"> <img src="/content/34/11.cover.gif" id="hw-login-cover-image" alt="Cover" width="59" height="80" /> <div id="hw-login-content-item"><span id="hw-login-item-view">Full Text (PDF)</span> <div class="cit creative-commons creative-commons-by-nc/4.0/ has-earlier-version from-current-issue"> <div class="cit-metadata"><span class="cit-first-element cit-section">Resource<span class="cit-sep cit-sep-after-article-section">:</span> </span><span class="cit-title">Chromosome-level subgenome-aware de novo assembly provides insight into <em>Saccharomyces bayanus</em> genome divergence after hybridization </span><ul class="cit-auth-list"> <li class="first-item"><span class="cit-auth cit-auth-type-author">Cory Gardner</span><span class="cit-sep cit-sep-separator">, </span></li> <li><span class="cit-auth cit-auth-type-author">Junhao Chen</span><span class="cit-sep cit-sep-separator">, </span></li> <li><span class="cit-auth cit-auth-type-author">Christina Hadfield</span><span class="cit-sep cit-sep-separator">, </span></li> <li><span class="cit-auth cit-auth-type-author">Zhaolian Lu</span><span class="cit-sep cit-sep-separator">, </span></li> <li><span class="cit-auth cit-auth-type-author">David Debruin</span><span class="cit-sep cit-sep-separator">, </span></li> <li><span class="cit-auth cit-auth-type-author">Yu Zhan</span><span class="cit-sep cit-sep-separator">, </span></li> <li><span class="cit-auth cit-auth-type-author">Maureen J. Donlin</span><span class="cit-sep cit-sep-separator">, </span></li> <li><span class="cit-auth cit-auth-type-author">Tae-Hyuk Ahn</span><span class="cit-sep cit-sep-separator">, </span></li> <li class="last-item"><span class="cit-sep cit-sep-last-separator">and </span><span class="cit-auth cit-auth-type-author">Zhenguo Lin</span></li> </ul> <cite><abbr title="Genome Research" class="site-title">Genome Res.</abbr> <span class="cit-print-date">November 2024 </span><span class="cit-vol">34<span class="cit-sep cit-sep-after-article-vol">: </span></span><span class="cit-pages"><span class="cit-first-page">2133</span><span class="cit-sep">-</span><span class="cit-last-page">2146</span></span><span class="cit-sep cit-sep-after-article-pages">; </span><span class="cit-ahead-of-print-date"><span class="cit-sep cit-sep-before-article-ahead-of-print-date">Published in Advance </span>September 17, 2024<span class="cit-sep cit-sep-after-article-ahead-of-print-date">, </span> </span><span class="cit-doi"><span class="cit-sep cit-sep-before-article-doi">doi:</span>10.1101/gr.279364.124 </span></cite> </div> <div class="cit-extra"> <ul class="cit-views"> <li class="first-item"><a href="/content/34/11/2133.abstract" rel="abstract">Abstract</a></li> <li><a href="/content/34/11/2133.full" rel="full-text">Full Text</a></li> <li><a href="/content/34/11/2133.full.pdf+html" rel="full-text.pdf">Full Text (PDF)</a></li> <li class="last-item"><a href="/content/34/11/2133/suppl/DC1" rel="supplemental-data" class="dslink-supplemental-material">Supplemental Material</a></li> </ul> </div> </div> </div> </div> </div> <div id="hw-login-instruction">To view this item, select one of the options below:</div> <div id="hw-login-sign-in-group"> <div id="hw-login-sign-in-header" class="hw-login-section-header"> <img alt="*" width="9" height="15" src="/shared/img/pages/login/redtri.gif" /> Sign In </div> <div id="hw-login-sign-in-box"> <form action="/content/34/11/2133.full.pdf" method="post" class="hw-ac-standalone-form hw-login-form"> <fieldset> <input value="" type="hidden" name="login_referer" /> <legend class="ext-legend">Sign In</legend> <span> <label for="username"> User Name </label> <input type="text" name="username" value="" size="10" maxlength="150" tabindex="1" id="username" /> </span> <span> <label for="password">Password</label> <input type="password" name="code" value="" size="10" maxlength="128" tabindex="2" id="password" /> </span> <span class="login-submit"> <input type="submit" name="signin" value="Sign In" tabindex="3" /></span> <span class="save-pwd"> <input type="checkbox" name="storepwd" value="yes" id="savepwd" /> <label for="savepwd">Remember my user name & password.</label> </span> </fieldset> <div id="hw-login-forgot-pwd"> <a href="http://www.cshlp.org/cgi/recnamepwd">Forgot</a> your user name or password? </div> <ul class="hw-login-option-list"> <li> <a href="/help/subscriptions/privacy-policy#cookie-problems">Can't get past this page?</a> </li> <li> <a href="/help/subscriptions/privacy-policy">Help with Cookies.</a> </li> <li> <a href="/site/subscriptions">Need to Activate?</a> </li> </ul> </form> </div> </div> <div id="hw-login-ppv-group" class="hw-login-extra-group"> <div id="hw-login-ppv-header" class="hw-login-section-header"><img alt="*" width="9" height="15" src="/shared/img/pages/login/redtri.gif" /> Purchase Short-Term Access </div> <ul id="hw-login-ppv-options" class="hw-login-option-list"> <li id="hw-login-ppa-option"><a href="/cookietest?for=ppv&uri=%2Fcgi%2Fsecure_ppv%3Fjcode%3Dgenome%26resource_id%3Dgenome%3Bgr.279364.124%26type%3Dppv%26ppv_type%3Darticle%26url%3Dhttp%253A%252F%252Fgenome.cshlp.org%252Fcontent%252F34%252F11%252F2133.full.pdf">Pay per Article </a> - You may access <strong>this article</strong> (from the computer you are currently using) for 1 <span>day</span> for US$20.00. </li> <li id="hw-login-ppv-regain-option"><a href="/cookietest?for=ppv&uri=%2Fcgi%2Fsecure_ppvregain%3Furl%3Dhttp%253A%252F%252Fgenome.cshlp.org%252Fcontent%252F34%252F11%252F2133.full.pdf">Regain Access</a> - You can regain access to a recent Pay per Article purchase if your access period has not yet expired. </li> </ul> </div> <div id="hw-login-sign-up-group" class="hw-login-extra-group"> <div id="hw-login-sign-up-header" class="hw-login-section-header"><img alt="*" width="9" height="15" src="/shared/img/pages/login/redtri.gif" /> Sign Up </div> <ul class="hw-login-option-list hw-login-section-body"> <li> <a href="/subscriptions"> Subscribe to the Journal </a> - Subscribe to the print and/or online journal. </li> </ul> </div> <div id="content-end-sb" class="sb-div"></div> </div> <div id="col-2"> <div class="content-box" id="article-cb-main"> <div class="cb-contents"> <h3 class="cb-contents-header"><span>This Article</span></h3> <div class="cb-section cb-slug"> <ol> <li> <div id="slugline"> <span class="slug-metadata-note ahead-of-print"> Published in Advance <span class="slug-ahead-of-print-date">September 17, 2024</span>, doi: <span title="10.1101/gr.279364.124" class="slug-doi">10.1101/gr.279364.124 </span> </span> <cite> <abbr title="Genome Research" class="slug-jnl-abbrev"> Genome Res.</abbr><span class="slug-pub-date"> 2024. </span> <span class="slug-vol"> 34: </span><span class="slug-pages"> 2133-2146 </span> </cite> <a href="/site/misc/terms.xhtml"> <nlm:copyright-statement xmlns:nlm="http://schema.highwire.org/NLM/Journal" xmlns:hwp="http://schema.highwire.org/Journal" hwp:id="copyright-statement-1"> <nlm:ext-link xmlns:l="http://schema.highwire.org/Linking" xmlns:xlink="http://www.w3.org/1999/xlink" l:rel="related" l:ref-type="uri" l:ref="http://genome.cshlp.org/site/misc/terms.xhtml" ext-link-type="uri" xlink:href="http://genome.cshlp.org/site/misc/terms.xhtml" hwp:id="ext-link-1">漏 2024 Gardner et al.; Published by Cold Spring Harbor Laboratory Press</nlm:ext-link> </nlm:copyright-statement></a> </div> </li> </ol> </div> <div class="cb-section" id="cb-art-links"> <ol> <li><a href="/content/34/11/2133.full.pdf" class="pdf-direct-link">Show PDF in full window</a></li> <li><a href="/content/34/11/2133.abstract" rel="view-abstract">Abstract</a><span class="free">Free</span></li> <li class="notice"><a href="/content/34/11/2133.full" rel="view-full-text">Full Text</a></li> <li class="notice"><span class="variant-indicator">禄 <span>Full Text (PDF)</span></span></li> <li><a href="/content/34/11/2133/suppl/DC1" rel="supplemental-data" class="dslink-supplemental-material">Supplemental Material</a></li> </ol> </div> <div class="cb-section collapsible" id="cb-art-cat"> <h4 class="cb-section-header"><span>Article Category</span></h4> <ol> <li> <ul class="subject-headings last-child"> <li><a class="tocsection-search" href="/search?tocsectionid=Resources&sortspec=date&submit=Submit">Resource</a></li> </ul> </li> </ol> </div> <div class="cb-section collapsible default-closed" id="cb-art-svcs"> <h4 class="cb-section-header"><span>Services</span></h4> <ol> <li><a href="/cgi/alerts/ctalert?alertType=citedby&addAlert=cited_by&cited_by_criteria_resid=genome%3B34%2F11%2F2133&saveAlert=no&return-type=article&return_url=http://genome.cshlp.org/content/34/11/2133.full.pdf">Alert me when this article is cited</a></li> <li><a href="/cgi/alerts/ctalert?alertType=correction&addAlert=correction&correction_criteria_value=34/11/2133&saveAlert=no&return-type=article&return_url=http://genome.cshlp.org/content/34/11/2133.full.pdf">Alert me if a correction is posted</a></li> <li><a href="/search?qbe=genome%3Bgr.279364.124&citation=Gardner%20et%20al.%2034%20%2811%29:%202133&submit=yes">Similar articles in this journal</a></li> <li><a href="/external-ref?access_num=genome%3B34%2F11%2F2133&link_type=ISI_RELATEDRECORDS" id="cb-isi-similar-articles">Similar articles in Web of Science</a></li> <li class="usage-stats-link icon-link"><a href="/articleusage?gca=genome;34/11/2133" rel="nofollow">Article Metrics</a></li> <li><a href="/external-ref?access_num=39288995&link_type=MED_NBRS">Similar articles in PubMed</a></li> <li><a href="/citmgr?gca=genome%3B34%2F11%2F2133">Download to citation manager</a></li> <li><a href="/site/misc/permissions_landing.xhtml"> Permissions </a></li> </ol> </div> <div class="cb-section collapsible default-closed" id="cb-art-cit"> <h4 class="cb-section-header"><span>Citing Articles</span></h4> <ol> <li><a href="/content/34/11/2133.full.pdf?cited-by=yes&legid=genome;34/11/2133#cited-by" id="cb-hw-citing-articles">Load citing article information</a></li> <li><a href="/external-ref?access_num=%2Fgenome%2F34%2F11%2F2133&link_type=ISI_CITING&accnum_type=native" rel="external-nw" id="cb-isi-citing-articles">Citing articles via Web of Science</a></li> </ol> </div> <div class="cb-section collapsible default-closed" id="cb-art-gs"> <h4 class="cb-section-header"><span>Google Scholar</span></h4> <ol> <li><a href="http://scholar.google.com/scholar?q=%22author%3AGardner%20author%3AC.%22">Articles by Gardner, C.</a></li> <li><a href="http://scholar.google.com/scholar?q=%22author%3ALin%20author%3AZ.%22">Articles by Lin, Z.</a></li> </ol> </div> <div class="cb-section collapsible default-closed" id="cb-art-pm"> <h4 class="cb-section-header"><span>PubMed/NCBI</span></h4> <ol> <li><a href="/external-ref?access_num=39288995&link_type=PUBMED">PubMed citation</a></li> <li><a href="/external-ref?access_num=Gardner%20C&link_type=AUTHORSEARCH">Articles by Gardner, C.</a></li> <li><a href="/external-ref?access_num=Lin%20Z&link_type=AUTHORSEARCH">Articles by Lin, Z.</a></li> <li> <div id="cb-entrez-links-placeholder"><a href="/entrez-links/39288995"></a></div> </li> </ol> </div> <div class="cb-section collapsible default-closed" id="cb-art-orcid"> <h4 class="cb-section-header"><span>ORCID</span></h4> <ol> <li class="cb-art-orcid-auth author-link"> <span xmlns="" class="orcid-author">Profile for Ahn, T. H.<a class="orcid-link" href="http://orcid.org/0000-0002-7281-9459">http://orcid.org/0000-0002-7281-9459</a></span> </li> <li class="cb-art-orcid-auth author-link"> <span xmlns="" class="orcid-author">Profile for Lin, Z.<a class="orcid-link" href="http://orcid.org/0000-0002-8400-9138">http://orcid.org/0000-0002-8400-9138</a></span> </li> </ol> </div> <div class="cb-section collapsible default-closed" id="cb-art-soc"> <h4 class="cb-section-header"><span>Share</span></h4> <ol> <li><a href="/email?gca=genome%3B34%2F11%2F2133&current-view-path=/content/34/11/2133.full.pdf"></a></li> </ol> </div> </div> </div> <div class="content-box" id="art-history-pane"> <div class="cb-contents"> <div class="cb-section collapsible default-closed" id="cb-art-gs"> <h4 class="cb-section-header"> <span>Preprint Server</span> </h4> <div id="art-history"></div> </div> </div> </div> <div class="content-box" id="article-cb-main"> <div class="cb-contents"> <div class="cb-section collapsible default-closed" id="cb-art-gs-cshl"></div> </div> </div> <div id="col-2-widget-placeholder"> <br /> <br /> </div> <ul class="tower-ads"> <li class="no-ad tower_col_2"><span> </span></li> </ul> </div> <div id="col-3"> <div class="content-box" id="sidebar-current-issue"> <div class="cb-contents"> <h3 class="cb-contents-header"><span>Current Issue</span></h3> <div class="cb-section"> <ol> <li><span><a href="/content/current" rel="current-issue">November 2024, 34 (11)</a></span></li> </ol> </div> <div class="cb-section"> <ol> <li> <div class="current-issue"><a href="/content/current" rel="current-issue"><img src="/content/34/11.cover.gif" width="67" height="89" alt="Current Issue" /></a></div> </li> </ol> </div> <cb:item xmlns:cb="http://schema.highwire.org/Site/Content-Box"> <div class="cb-section collapsible default-closed" id="sidebar-cur-issue-coverlines"> <h4 class="cb-section-header"> <span>From the Cover</span> </h4> <ul> <li> <a href="/site/cl/CL_34_11_dis_canc.xhtml">Rare disease and cancer genomics</a> </li> <li> <a href="/site/cl/CL_34_11_long_read.xhtml">Long-read RNA sequencing</a> </li> <li> <a href="/site/cl/CL_34_11_chrom_lev.xhtml">T2T and chromosome-level assemblies</a> </li> <li> <a href="/site/cl/CL_34_11_data_app.xhtml">Novel long-read sequencing data approaches</a> </li> <li> <a href="/site/cl/CL_34_11_det_char.xhtml">Rapid pathogen detection and characterization</a> </li> </ul> </div> </cb:item> <div class="cb-section sidebar-etoc-link"> <ol> <li><a href="/cgi/alerts/etoc">Alert me to new issues of <span class="journal-name"> Genome Research </span> </a></li> </ol> </div> </div> </div> <div id="sidebar-global-nav"> <ul class="button-list pub-links"> <li class="first"><a href="/content/early/recent" title="Advance Online Articles "><span>Advance Online Articles </span></a></li> <li><a href="http://submit.genome.org/" rel="external-nw" title="Submit a Manuscript"><span>Submit a Manuscript</span></a></li> <li><a href="/site/press/Announcements.xhtml" title="GR in the News "><span>GR in the News </span></a></li> <li><a href="/site/misc/about.xhtml" title="Editorial Board"><span>Editorial Board</span></a></li> <li><a href="/site/misc/permissions_landing.xhtml" title="Permissions"><span>Permissions</span></a></li> <li><a href="/site/misc/alertland.xhtml" title="E-mail Alerts & RSS Feeds"><span>E-mail Alerts & RSS Feeds</span></a></li> <li><a href="http://www.cshlpress.com/library/?hwinfo" title="Recommend to Your Library"><span>Recommend to Your Library</span></a></li> <li class="last"><a href="/site/misc/classifieds.xhtml" title="Job Opportunities"><span>Job Opportunities</span></a></li> </ul> </div> <ul class="tower-ads"> <li><a href="/cgi/adclick/?ad=57881&adclick=true&url=https%3A%2F%2Fbit.ly%2F3XReZAs" target="_blank"><img class="adborder0" title="Oxford Nanopore" src="//genome.cshlp.org/adsystem/graphics/45268010153785954/genome/ONT%20Tower%20Bolder.jpg?ad=57881&adview=true" alt="Oxford Nanopore" /></a></li> </ul> <div id="col-3-widget-placeholder" style="padding-top:12px;"></div> </div> <div id="footer"> <div class="bar"> <div class="footer-group footer-col-left"> <ul class="button-list footer-buttons"> <li class="first"><a href="/" title="Home"><span>Home</span></a></li> <li><a href="/site/misc/about.xhtml" title="About"><span>About</span></a></li> <li><a href="/content/by/year" title="Archive"><span>Archive</span></a></li> <li><a href="http://submit.genome.org/" title="Submit"><span>Submit</span></a></li> <li><a href="/site/subscriptions/" title="Subscribe"><span>Subscribe</span></a></li> <li><a href="/site/misc/adinfo.xhtml" title="Advertise"><span>Advertise</span></a></li> <li><a href="/site/misc/ifora.xhtml" title="Author Info"><span>Author Info</span></a></li> <li><a href="/feedback" title="Contact"><span>Contact</span></a></li> <li class="last"><a href="/help/" title="Help"><span>Help</span></a></li> </ul> <p class="copyright"><a href="http://www.cshlpress.com/" rel="external-nw">Copyright 漏 2024 by Cold Spring Harbor Laboratory Press</a></p> </div> <div class="footer-group footer-col-right"> <ul class="issns"> <li> <span>Print ISSN: </span> <span class="issn">1088-9051</span> </li> <li> <span>Online ISSN: </span> <span class="issn">1549-5469</span> </li> </ul> </div> </div> <div class="block-2 sb-div"></div> <script type="text/javascript"> document.write(unescape("%3Cscript async src='https://www.googletagmanager.com/gtag/js?id=G-R8GM9H68DV'%3E%3C/script%3E")); </script><script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-R8GM9H68DV'); </script> </div><script type="text/javascript"> document.write(unescape("%3Cscript async src='https://www.googletagmanager.com/gtag/js?id=G-1CWXPJ6EVC'%3E%3C/script%3E")); </script><script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-1CWXPJ6EVC'); </script></div> </body> </html>