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Prime Medicine | Delivering on the promise of Prime Editing

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style="background-image:url('https://primemedicine.com/wp-content/uploads/2022/07/banner-home.png');"> <div class="container-fluid"> <div class="row"> <div class="col-lg-5 col-md-7 content"> <h1>Delivering on the promise of <span class="nodelete">Prime Editing</span></h1> </div> </div> </div> </div> <div class="section section-padding" id="section-1"> <div class="container-fluid"> <h2 class="section-label">about</h2> <div class="row"> <div class="col-md-12"> <div class="content"> <p class="headline">Prime Medicine™ was founded with a goal of transforming the lives of patients with debilitating diseases through the application of our groundbreaking Prime Editing platform and technology. We use Prime Editing, a next-generation gene editing approach that we believe can<br /> address the genetic cause of disease and potentially provide patients with long-lasting cures. Prime Editing searches to find the precise place in the genome to edit and replaces the segment of faulty DNA with a correct copy of DNA.</p> <p class="headline">We envision a world where this approach can change the course of how disease is treated to provide potentially lifelong benefit to patients and shape the future of gene editing.</p> <p style="text-align: right;"><a class="btn btn-blue" href="/about">learn more_</a></p> </div> </div> </div> </div> </div> <div class="section section-padding" id="section-2"> <div class="sub-section section-padding-sm"> <div class="container-fluid"> <h2 class="section-label">science</h2> <div class="row"> <div class="col-md-4"> <div class="content"> <h2>next- generation gene editing</h2> </div> </div> </div> </div> </div> <div class="sub-section section-padding-sm bg-purple"> <div class="container-fluid"> <div class="row"> <div class="col-md-4 dark"> <div class="content"> <p>We believe Prime Editing technology has broad potential – that it could theoretically address about 90% of known disease-causing mutations across many organisms, organs and cell types. Versatile, precise and efficient, Prime Editing is designed to work broadly across most types of gene mutations at the natural genomic location, while minimizing unwanted DNA modifications. This approach uses a process designed to produce a wide variety of precise, predictable and efficient genetic outcomes at the targeted sequence, which we believe will dramatically increase the impact of gene editing for a broad range of therapeutic applications.</p> </div> </div> </div> </div> </div> <div class="sub-section"> <div class="container-fluid"> <div class="row"> <div class="col-md-8 col-md-offset-4"> <div class="content box-padding bg-gray" id="approach-wrapper"> <p><img decoding="async" class="alignnone size-full wp-image-191" style="width: 575px; margin: 0 auto; display: block;" src="https://primemedicine.wpengine.com/wp-content/uploads/2022/07/Prime_step-3_Graphic_062121_transparent.png" alt="" width="1000" height="774" srcset="https://primemedicine.com/wp-content/uploads/2022/07/Prime_step-3_Graphic_062121_transparent.png 1000w, https://primemedicine.com/wp-content/uploads/2022/07/Prime_step-3_Graphic_062121_transparent-300x232.png 300w, https://primemedicine.com/wp-content/uploads/2022/07/Prime_step-3_Graphic_062121_transparent-768x594.png 768w" sizes="(max-width: 1000px) 100vw, 1000px" /></p> <h3>Approach</h3> <p>Prime Editing is a technology that acts like a DNA word processor to “search and replace” disease-causing genetic sequences at their precise location in the genome, without causing double-strand DNA breakage.</p> <p style="margin-bottom: 0;"><a class="btn btn-blue" href="/science">our science_</a></p> </div> </div> </div> </div> </div> </div> <div class="section section-padding" id="section-3"> <div class="container-fluid"> <h2 class="section-label">Media</h2> <!-- IR feed --> <div class="row news flex flex-boxes"> <div class="col-md-4 content flex flex-boxes"> <a class="news-titles" href="https://investors.primemedicine.com/news-releases/news-release-details/prime-medicine-reports-third-quarter-2024-financial-results-and"> <h4>11_12_24</h4> <h3>Prime Medicine Reports Third Quarter 2024 Financial Results and Provides Business Updates</h3> </a> </div> <div class="col-md-4 content flex flex-boxes"> <a class="news-titles" href="https://investors.primemedicine.com/news-releases/news-release-details/prime-medicine-participate-upcoming-investor-conferences-1"> <h4>11_6_24</h4> <h3>Prime Medicine to Participate in Upcoming Investor Conferences</h3> </a> </div> <div class="col-md-4 content flex flex-boxes"> <a class="news-titles" href="https://investors.primemedicine.com/news-releases/news-release-details/prime-medicine-presents-vivo-proof-concept-data-highlighting"> <h4>10_24_24</h4> <h3>Prime Medicine Presents In Vivo Proof-of-Concept Data Highlighting Interim Preclinical Advances in its Wilson’s Disease Program and the Broad Potential of its Universal Liver-Targeted LNP at ESGCT 31st Annual Congress</h3> </a> </div> </div> <div class="row"> <div class="col-md-12 content"> <p class="text-center"><a class="btn btn-blue" href="https://primemedicine.gcs-web.com/news-events/news-releases">View More_</a></p> </div> </div> </div> </div> <div class="section bg-yellow" id="section-4"> <div class="container-fluid"> <h2 class="section-label">careers</h2> <div class="row"> <div class="col-md-6"> <img class="img-responsive image-shift" src="https://primemedicine.com/wp-content/uploads/2022/07/Candid-for-home-page.png" alt="" /> </div> <div class="col-md-6"> <div class="content"> <h2>join us</h2> <p>Realizing the promise of Prime Editing requires a great team. Prime team members are dedicated, scientifically curious and passionate about helping patients live longer, healthier lives. A career at Prime Medicine is an opportunity to shape the future of gene editing.</p> <p><a class="btn btn-blue" href="/careers">current opportunities_</a></p> </div> </div> </div> </div> </div> </div> <footer class="dark"> <div class="container"> <div class="row"> <div class="col-md-12 content"> <a href="https://primemedicine.com"><h1 class="text-center">prime_</h1></a> </div> </div> <div class="row"> <div class="col-md-12"> <ul id="menu-footer-menu" class="nav navbar-nav"><li id="menu-item-211" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-211"><a href="https://primemedicine.com/about/"><span class="nav-label">About<span class="underscore">_</span></span></a></li> <li id="menu-item-214" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-214"><a href="https://primemedicine.com/science/"><span class="nav-label">Science<span class="underscore">_</span></span></a></li> <li id="menu-item-482" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-482"><a href="https://investors.primemedicine.com"><span class="nav-label">Investors<span class="underscore">_</span></span></a></li> <li id="menu-item-212" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-212"><a href="https://primemedicine.com/careers/"><span class="nav-label">Careers<span class="underscore">_</span></span></a></li> <li id="menu-item-215" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-215"><a target="_blank" href="https://www.linkedin.com/company/prime-medicine/"><span class="nav-label"><i class="fab fa-linkedin-in"></i><span class="underscore">_</span></span></a></li> <li id="menu-item-571" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-571"><a target="_blank" href="https://twitter.com/PrimeMedicine"><span class="nav-label"><i class="fab fa-twitter"></i><span class="underscore">_</span></span></a></li> </ul> </div> </div> <div class="row"> <div class="col-md-12 content"> <p class="text-center"><a href="mailto:info@primemedicine.com">Contact Us</a> | <a href="/privacy-policy">Privacy Policy</a> | <a href="/terms-of-use">Terms of Use</a></p> </div> </div> <div class="row"> <div class="col-md-12 content"> <p class="text-center">© 2021-2023 Prime Medicine, Inc. 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