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Search results for: onset of action

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text-center" style="font-size:1.6rem;">Search results for: onset of action</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3044</span> 5-[Aryloxypyridyl (or Nitrophenyl)]-4H-1,2,4-Triazoles as Flexible Benzodiazepine Analogs: Synthesis, Receptor Binding Affinity and the Lipophilicity-Dependent Anti-Seizure Onset of Action</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Latifeh%20Navidpour">Latifeh Navidpour</a>, <a href="https://publications.waset.org/abstracts/search?q=Shabnam%20Shabani"> Shabnam Shabani</a>, <a href="https://publications.waset.org/abstracts/search?q=Alireza%20Heidari"> Alireza Heidari</a>, <a href="https://publications.waset.org/abstracts/search?q=Manouchehr%20Bashiri"> Manouchehr Bashiri</a>, <a href="https://publications.waset.org/abstracts/search?q=Azadeh%20Ebrahim-Habibi"> Azadeh Ebrahim-Habibi</a>, <a href="https://publications.waset.org/abstracts/search?q=Soraya%20Shahhosseini"> Soraya Shahhosseini</a>, <a href="https://publications.waset.org/abstracts/search?q=Hamed%20Shafaroodi"> Hamed Shafaroodi</a>, <a href="https://publications.waset.org/abstracts/search?q=Sayyed%20Abbas%20Tabatabai"> Sayyed Abbas Tabatabai</a>, <a href="https://publications.waset.org/abstracts/search?q=Mahsa%20Toolabi"> Mahsa Toolabi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A new series of 5-(2-aryloxy-4-nitrophenyl)-4H-1,2,4-triazoles and 5-(2-aryloxy-3-pyridyl)-4H-1,2,4-triazoles, possessing C-3 thio or alkylthio substituents, was synthesized and evaluated for their benzodiazepine receptor affinity and anti-seizure activity. These analogues revealed similar to significantly superior affinity to GABAA/ benzodiazepine receptor complex (IC50 values of 0.04–4.1 nM), relative to diazepam as the reference drug (IC50 value of 2.4 nM). To determine the onset of anti-seizure activity, the time-dependent effectiveness of i.p. administration of compounds on pentylenetetrazole induced seizure threshold was studied and a very good relationship was observed between the lipophilicity (cLogP) and onset of action of studied analogues (r2 = 0.964). The minimum effective dose of the compounds, determined at the time the analogues showed their highest activity, was demonstrated to be 0.025–0.1 mg/kg, relative to diazepam (0.025 mg/kg). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=1" title="1">1</a>, <a href="https://publications.waset.org/abstracts/search?q=2" title="2">2</a>, <a href="https://publications.waset.org/abstracts/search?q=4-triazole" title="4-triazole">4-triazole</a>, <a href="https://publications.waset.org/abstracts/search?q=flexible%20benzodiazepines" title=" flexible benzodiazepines"> flexible benzodiazepines</a>, <a href="https://publications.waset.org/abstracts/search?q=GABAA%2Fbezodiazepine%20receptor%20complex" title=" GABAA/bezodiazepine receptor complex"> GABAA/bezodiazepine receptor complex</a>, <a href="https://publications.waset.org/abstracts/search?q=onset%20of%20action" title=" onset of action"> onset of action</a>, <a href="https://publications.waset.org/abstracts/search?q=PTZ%20induced%20seizure%20threshold" title=" PTZ induced seizure threshold"> PTZ induced seizure threshold</a> </p> <a href="https://publications.waset.org/abstracts/136418/5-aryloxypyridyl-or-nitrophenyl-4h-124-triazoles-as-flexible-benzodiazepine-analogs-synthesis-receptor-binding-affinity-and-the-lipophilicity-dependent-anti-seizure-onset-of-action" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/136418.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">104</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3043</span> Thiopental-Fentanyl versus Midazolam-Fentanyl for Emergency Department Procedural Sedation and Analgesia in Patients with Shoulder Dislocation and Distal Radial Fracture-Dislocation: A Randomized Double-Blind Controlled Trial</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=D.%20Farsi">D. Farsi</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20Dokhtvasi"> G. Dokhtvasi</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Abbasi"> S. Abbasi</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Shafiee%20Ardestani"> S. Shafiee Ardestani</a>, <a href="https://publications.waset.org/abstracts/search?q=E.%20Payani"> E. Payani </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background and aim:It has not been well studied whether fentanyl-thiopental (FT) is effective and safe for PSA in orthopedic procedures in Emergency Department (ED). The aim of this trial was to evaluate the effectiveness of intravenous FTversusfentanyl-midazolam (FM)in patients who suffered from shoulder dislocation or distal radial fracture-dislocation. Methods:In this randomized double-blinded study, Seventy-six eligible patients were entered the study and randomly received intravenous FT or FM. The success rate, onset of action and recovery time, pain score, physicians’ satisfaction and adverse events were assessed and recorded by treating emergency physicians. The statistical analysis was intention to treat. Results: The success rate after administrating loading dose in FT group was significantly higher than FM group (71.7% vs. 48.9%, p=0.04); however, the ultimate unsuccess rate after 3 doses of drugs in the FT group was higher than the FM group (3 to 1) but it did not reach to significant level (p=0.61). Despite near equal onset of action time in two study group (P=0.464), the recovery period in patients receiving FT was markedly shorter than FM group (P<0.001). The occurrence of adverse effects was low in both groups (p=0.31). Conclusion: PSA using FT is effective and appears to be safe for orthopedic procedures in the ED. Therefore, regarding the prompt onset of action, short recovery period of thiopental, it seems that this combination can be considered more for performing PSA in orthopedic procedures in ED. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=procedural%20sedation%20and%20analgesia" title="procedural sedation and analgesia">procedural sedation and analgesia</a>, <a href="https://publications.waset.org/abstracts/search?q=thiopental" title=" thiopental"> thiopental</a>, <a href="https://publications.waset.org/abstracts/search?q=fentanyl" title=" fentanyl"> fentanyl</a>, <a href="https://publications.waset.org/abstracts/search?q=midazolam" title=" midazolam"> midazolam</a>, <a href="https://publications.waset.org/abstracts/search?q=orthopedic%20procedure" title=" orthopedic procedure"> orthopedic procedure</a>, <a href="https://publications.waset.org/abstracts/search?q=emergency%20department" title=" emergency department"> emergency department</a>, <a href="https://publications.waset.org/abstracts/search?q=pain" title=" pain"> pain</a> </p> <a href="https://publications.waset.org/abstracts/18225/thiopental-fentanyl-versus-midazolam-fentanyl-for-emergency-department-procedural-sedation-and-analgesia-in-patients-with-shoulder-dislocation-and-distal-radial-fracture-dislocation-a-randomized-double-blind-controlled-trial" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/18225.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">252</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3042</span> Physiotherapy Program for Frozen Shoulder on Pain, Onset of Symptom and Obtaining Modalities</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Narupon%20Kunbootsri">Narupon Kunbootsri</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20Kraipoj"> J. Kraipoj</a>, <a href="https://publications.waset.org/abstracts/search?q=K.%20Phandech"> K. Phandech</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20Sirasaporn"> P. Sirasaporn</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Physiotherapy is one of the treatments for frozen shoulder but there was no data about the treatment of physiotherapy. Moreover, it is question about onset of symptom before physiotherapy program and obtaining physical modalities and delayed start physiotherapy program lead to delayed improvement. Thus the aim of this study was to investigate physiotherapy program for frozen shoulder on pain score, onset of symptom and obtaining physical modalities. A retrospective study design was conducted. 182 medical records of patients with frozen shoulder were reviewed. These frozen shoulders were treated at physiotherapy unit, department of Rehabilitation last 3 years (January, 2014- December, 2016). The data consist of onset of symptom, pain score and obtaining physical modalities were recorded. There was a statistically significant improve in pain score, pretreatment score mean 7.24±1.52 and the last follow up pain score mean 3.88± 1.0 [mean difference 3.18 with 95%CI were [2.45- 3.92]. In addition, the onset of symptoms was 145 days before obtaining physiotherapy program. The physical modalities used frequently were hot pack 14.8% and ultrasound diathermy 13.7%. In conclusion, the retrospective study show physiotherapy program including, hot pack and ultrasound diathermy seem to be useful for frozen shoulder in term of pain score. But onset of symptom is too long to start physiotherapy programs. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=frozen%20shoulder" title="frozen shoulder">frozen shoulder</a>, <a href="https://publications.waset.org/abstracts/search?q=physiotherapy" title=" physiotherapy"> physiotherapy</a>, <a href="https://publications.waset.org/abstracts/search?q=pain%20score" title=" pain score"> pain score</a>, <a href="https://publications.waset.org/abstracts/search?q=onset%20of%20symptom" title=" onset of symptom"> onset of symptom</a>, <a href="https://publications.waset.org/abstracts/search?q=physical%20modality" title=" physical modality"> physical modality</a> </p> <a href="https://publications.waset.org/abstracts/87988/physiotherapy-program-for-frozen-shoulder-on-pain-onset-of-symptom-and-obtaining-modalities" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/87988.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">176</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3041</span> Antenatal Factors Associated with Early Onset Neonatal Sepsis among Neonates 0-7 Days at Fort Portal Regional Referral Hospital</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Moses%20Balina">Moses Balina</a>, <a href="https://publications.waset.org/abstracts/search?q=Archbald%20Bahizi"> Archbald Bahizi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Early onset neonatal sepsis is a systemic infection in a newborn baby during the first week after birth and contributes to 50% of neonatal deaths each year. Risk factors for early onset neonatal sepsis, which can be maternal, health care provider, or health care facility associated, can be prevented with access to quality antenatal care. Objective: The objective of the study was to assess early onset neonatal sepsis and antenatal factors associated with Fort Portal Regional Referral Hospital. Methodology: A cross sectional study design was used. The study involved 60 respondents who were mothers of breastfeeding neonates being treated for early onset neonatal sepsis at Fort Portal Regional Referral Hospital neonatal intensive care unit. Simple random sampling was used to select study participants. Data were collected using questionnaires, entered in Stata 16, and analysed using logistic regression. Results: The prevalence of early onset neonatal sepsis at Fort Portal Regional Referral Hospital was 25%. Multivariate analysis revealed that institutional factors were the only antenatal factors found to be significantly associated with early onset neonatal sepsis at Fort Portal Regional Referral Hospital (p < 0.01). Bivariate analysis revealed that attending antenatal care at a health centre III or IV instead of a hospital (p = 0.011) and attending antenatal care in health care facilities with no laboratory investigations (p = 0.048) were risk factors for early onset neonatal sepsis in the newborn at Fort Portal Regional Referral Hospital. Conclusion: Antenatal factors were associated with early onset neonatal sepsis, and health care facility factors like lower level health centre and unavailability of quality laboratory investigations to pregnant women contributed to early onset neonatal sepsis in the newborn. Mentorships, equipping/stocking laboratories, and improving staffing levels were necessary to reduce early onset neonatal sepsis. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antenatal%20factors" title="antenatal factors">antenatal factors</a>, <a href="https://publications.waset.org/abstracts/search?q=early%20onset%20neonatal%20sepsis" title=" early onset neonatal sepsis"> early onset neonatal sepsis</a>, <a href="https://publications.waset.org/abstracts/search?q=neonates%200-7%20days" title=" neonates 0-7 days"> neonates 0-7 days</a>, <a href="https://publications.waset.org/abstracts/search?q=fort%20portal%20regional%20referral%20hospital" title=" fort portal regional referral hospital"> fort portal regional referral hospital</a> </p> <a href="https://publications.waset.org/abstracts/149830/antenatal-factors-associated-with-early-onset-neonatal-sepsis-among-neonates-0-7-days-at-fort-portal-regional-referral-hospital" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/149830.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">102</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3040</span> Effect of Rituximab Therapy Depending on the Age of Disease Onset in Systemic Sclerosis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Liudmila%20Garzanova">Liudmila Garzanova</a>, <a href="https://publications.waset.org/abstracts/search?q=Lidia%20Ananyeva"> Lidia Ananyeva</a>, <a href="https://publications.waset.org/abstracts/search?q=Olga%20Koneva"> Olga Koneva</a>, <a href="https://publications.waset.org/abstracts/search?q=Olga%20Ovsyannikova"> Olga Ovsyannikova</a>, <a href="https://publications.waset.org/abstracts/search?q=Oxana%20Desinova"> Oxana Desinova</a>, <a href="https://publications.waset.org/abstracts/search?q=Mayya%20Starovoytova"> Mayya Starovoytova</a>, <a href="https://publications.waset.org/abstracts/search?q=Rushana%20Shayahmetova"> Rushana Shayahmetova</a>, <a href="https://publications.waset.org/abstracts/search?q=Anna%20Khelkovskaya-Sergeeva"> Anna Khelkovskaya-Sergeeva</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objectives. The age of the disease onset could have an impact on the effect of therapy in systemic sclerosis(SSc). Late-age onset in SSc could have a more severe course of the disease and worse clinical effects on therapy. The aim of our study was to evaluate changes in skin fibrosis on rituximab(RTX) therapy in patients with SSc and different ages of the disease onset. Methods. 151 patients with SSc were included in this study. Patients were divided into groups depending on the age of the disease onset: group 1 - younger than 30 years (40 patients(26%), group 2 - 31-59 years (90 patients(60%) and group 3 – more than 60 years (21 patients(14%). The mean follow-up period was 13±2.3month. The mean age was 48±13years, female-83% of patients, and the diffuse cutaneous subset of the disease had 52% of patients. The mean disease duration was 6.4±5years. The cumulative mean dose of RTX was 1.5±0.6grams. Patients received RTX as a therapy for interstitial lung disease. All patients received prednisone at a dose of 11.6±4.8mg/day, immunosuppressants received 48% of them. The results at baseline and at the end of the follow-up are presented in the form of mean values. Results. There was a significant decrease of modified Rodnan skin score(mRss) in all groups: in group 1 - from 10.2±8 to 7.7±6.5(p=0.01); in group 2 - from 9±7.2 to 6.2±4.7(p=0.0001); in group 3 - from 20.5±14.1 to 10.8±9.4(p=0.001). There was a significant decrease of the activity index (EScSG-AI): in group 1 from 2.5±1.8 to 1.3±1.1; in group 2 – from 3.2±1.6 to 1.5±1.2; in group 3 – from 4.2±2.1 to 1.3±1. Conclusion. There was a significant improvement in skin fibrosis in a year after initiation of RTX therapy regardless of the age of the disease onset. The improvement was more pronounced in the group with late-age onset of the disease, but these data require further investigations. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=skin%20fibrosis" title="skin fibrosis">skin fibrosis</a>, <a href="https://publications.waset.org/abstracts/search?q=systemic%20sclerosis" title=" systemic sclerosis"> systemic sclerosis</a>, <a href="https://publications.waset.org/abstracts/search?q=rituximab" title=" rituximab"> rituximab</a>, <a href="https://publications.waset.org/abstracts/search?q=disease%20onset" title=" disease onset"> disease onset</a> </p> <a href="https://publications.waset.org/abstracts/189249/effect-of-rituximab-therapy-depending-on-the-age-of-disease-onset-in-systemic-sclerosis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/189249.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">31</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3039</span> Beneficial Effect of Chromium Supplementation on Glucose, HbA1C and Lipid Variables in Individuals with Newly Onset Type-2 Diabetes</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Baljinder%20Singh">Baljinder Singh</a>, <a href="https://publications.waset.org/abstracts/search?q=Navneet%20Sharma"> Navneet Sharma</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Chromium is an essential nutrient involved in normal carbohydrate and lipid metabolism. It influences glucose metabolism by potentiating the action as taking part in insulin signal amplification mechanism. A placebo-controlled single blind, prospective study was carried out to investigate the effect of chromium supplementation on blood glucose, HbA1C and lipid profile in newly onset patients with type-2 diabetes. Total 40 newly onset type-2 diabetics were selected and after one month stabilization further randomly divided into two groups viz. study group and placebo group. The study group received 9 gm brewer’s yeast (42 μ Cr) daily and the other placebo group received yeast devoid of chromium for 3 months. Subjects were instructed not to change their normal eating and living habits. Fasting blood glucose, HbA1C and lipid profile were analyzed at beginning and completion of the study. Results revealed that fasting blood glucose level significantly reduced in the subjects consuming yeast supplemented with chromium (197.65±6.68 to 103.68±6.64 mg/dl; p<0.001). HbA1C values improved significantly from 9.51±0.26% to 6.86±0.28%; p<0.001 indicating better glycaemic control. In experimental group total cholesterol, TG and LDL levels were also significantly reduced from 199.66±3.11 to 189.26±3.01 mg/dl; p<0.02, 144.94±8.31 to 126.01±8.26; p<0.05 and 119.19±1.71 to 99.58±1.10; p<0.001 respectively. These data demonstrate beneficial effect of chromium supplementation on glycaemic control and lipid variables in subjects with newly onset type-2 diabetes. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=type-2%20diabetes" title="type-2 diabetes">type-2 diabetes</a>, <a href="https://publications.waset.org/abstracts/search?q=chromium" title=" chromium"> chromium</a>, <a href="https://publications.waset.org/abstracts/search?q=glucose" title=" glucose"> glucose</a>, <a href="https://publications.waset.org/abstracts/search?q=HbA1C" title=" HbA1C"> HbA1C</a> </p> <a href="https://publications.waset.org/abstracts/10183/beneficial-effect-of-chromium-supplementation-on-glucose-hba1c-and-lipid-variables-in-individuals-with-newly-onset-type-2-diabetes" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/10183.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">242</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3038</span> A Retrospective Study on the Age of Onset for Type 2 Diabetes Diagnosis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20A.%20Hammad">Mohamed A. Hammad</a>, <a href="https://publications.waset.org/abstracts/search?q=Dzul%20Azri%20Mohamed%20Noor"> Dzul Azri Mohamed Noor</a>, <a href="https://publications.waset.org/abstracts/search?q=Syed%20Azhar%20Syed%20Sulaiman"> Syed Azhar Syed Sulaiman</a>, <a href="https://publications.waset.org/abstracts/search?q=Majed%20Ahmed%20Al-Mansoub"> Majed Ahmed Al-Mansoub</a>, <a href="https://publications.waset.org/abstracts/search?q=Muhammad%20Qamar"> Muhammad Qamar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> There is a progressive increase in the prevalence of early onset Type 2 diabetes mellitus. Early detection of Type 2 diabetes enhances the length and/or quality of life which might result from a reduction in the severity, frequency or prevent or delay of its long-term complications. The study aims to determine the onset age for the first diagnosis of Type 2 diabetes mellitus. A retrospective study conducted in the endocrine clinic at Hospital Pulau Pinang in Penang, Malaysia, January- December 2016. Records of 519 patients with Type 2 diabetes mellitus were screened to collect demographic data and determine the age of first-time diabetes mellitus diagnosis. Patients classified according to the age of diagnosis, gender, and ethnicity. The study included 519 patients with age (55.6±13.7) years, female 265 (51.1%) and male 254 (48.9%). The ethnicity distribution was Malay 191 (36.8%), Chinese 189 (36.4%) and Indian 139 (26.8%). The age of Type 2 diabetes diagnosis was (42±14.8) years. The female onset of diabetes mellitus was at age (41.5±13.7) years, while male (42.6±13.7) years. Distribution of diabetic onset by ethnicity was Malay at age (40.7±13.7) years, Chinese (43.2±13.7) years and Indian (42.3±13.7) years. Diabetic onset was classified by age as follow; ≤20 years’ cohort was 33 (6.4%) cases. Group >20- ≤40 years was 190 (36.6%) patients, and category >40- ≤60 years was 270 (52%) subjects. On the other hand, the group >60 years was 22 (4.2%) patients. The range of diagnosis was between 10 and 73 years old. Conclusion: Malay and female have an earlier onset of diabetes than Indian, Chinese and male. More than half of the patients had diabetes between 40 and 60 years old. Diabetes mellitus is becoming more common in younger age <40 years. The age at diagnosis of Type 2 diabetes mellitus has decreased with time. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=age%20of%20onset" title="age of onset">age of onset</a>, <a href="https://publications.waset.org/abstracts/search?q=diabetes%20diagnosis" title=" diabetes diagnosis"> diabetes diagnosis</a>, <a href="https://publications.waset.org/abstracts/search?q=diabetes%20mellitus" title=" diabetes mellitus"> diabetes mellitus</a>, <a href="https://publications.waset.org/abstracts/search?q=Malaysia" title=" Malaysia"> Malaysia</a>, <a href="https://publications.waset.org/abstracts/search?q=outpatients" title=" outpatients"> outpatients</a>, <a href="https://publications.waset.org/abstracts/search?q=type%202%20diabetes" title=" type 2 diabetes"> type 2 diabetes</a>, <a href="https://publications.waset.org/abstracts/search?q=retrospective%20study" title=" retrospective study"> retrospective study</a> </p> <a href="https://publications.waset.org/abstracts/74920/a-retrospective-study-on-the-age-of-onset-for-type-2-diabetes-diagnosis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/74920.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">414</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3037</span> Iqbal&#039;s Philosophy of Action in the Light of Contemporary Philosophy of Action</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sevcan%20Ozturk">Sevcan Ozturk</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of this paper is to analyze the twentieth-century Muslim philosopher Muhammad Iqbal’s philosophy of action in the light of the main issues of contemporary philosophy of action. Iqbal is one of the most celebrated and eminent figures of modern Islamic thought. However, a review of the works on Iqbal shows that most of the central concepts of his philosophy have not received enough attention. His notion of ‘action’ in its philosophical context is one of these concepts. One of the main characteristics of Iqbal’s approach is that he develops his discussion around the main themes of contemporary philosophy of action, which includes ontological and conceptual questions regarding the nature of human actions. He also discusses that action is the only way to develop human personality, and that the human being can only achieve immortality promised by Islam through his actions. Therefore, while presenting an approach that can be read in the light of contemporary philosophy of action, which has become one of the significant parts of modern philosophical discussions in the west particularly since the nineteenth century, he, at the same time, develops his own philosophy of action in the light of Islamic resources. Consequently, these two main characteristics of his discussion of the notion of action make his philosophy of action an important contribution to contemporary philosophy of action, a field that ignores the discussions of Muslim philosophers on action. Therefore, this paper aims at highlighting Iqbal’s contribution to the modern debate of action by analysing Iqbal’s notion of action in the light of the contemporary issues of philosophy of action. This will, first of all, include an examination of contemporary action theory. Although the main discussions of contemporary philosophy of action will provide the methodology of this study, the main paradigms of Iqbal’s approach to the notion of action will also be considered during the examination of the discussions of philosophy of action. Then, Iqbal’s own philosophy of action will be established in the light of the contemporary philosophy of action. It is hoped that this paper will cultivate a dialogue between Iqbal scholars and those working in the field of philosophy of action, and that it will be a contribution to the fields of Iqbal studies, philosophy of action, and intercultural philosophy. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=action" title="action">action</a>, <a href="https://publications.waset.org/abstracts/search?q=development%20of%20personality" title=" development of personality"> development of personality</a>, <a href="https://publications.waset.org/abstracts/search?q=Muhammad%20Iqbal" title=" Muhammad Iqbal"> Muhammad Iqbal</a>, <a href="https://publications.waset.org/abstracts/search?q=philosophy%20of%20action" title=" philosophy of action"> philosophy of action</a> </p> <a href="https://publications.waset.org/abstracts/64781/iqbals-philosophy-of-action-in-the-light-of-contemporary-philosophy-of-action" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/64781.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">371</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3036</span> Physiotherapy Program for Frozen Shoulder Related to Onset of Symptom, Range of Motions and Obtaining Modalities</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Narupon%20Kunbootsri">Narupon Kunbootsri</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20Sirasaporn"> P. Sirasaporn </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Frozen shoulder is a common problem present by pain and limit range of motion. The prevalence of frozen shoulder showed 18-31% of population. The effect of frozen shoulder lead to limit activities daily living life, high medical care cost and so on. Physiotherapy is one of the treatments for frozen shoulder but there was no data about the treatment of physiotherapy. Moreover, it is question about onset of symptom relate to physiotherapy program and obtaining physical modalities and delayed start physiotherapy program lead to delayed improvement. Thus the aim of this study was to investigate physiotherapy program for frozen shoulder relate to onset of symptom, range of motion and obtaining physical modalities. A retrospective study design was conducted. 182 medical records of patients with frozen shoulder were reviewed. These frozen shoulders were treated at physiotherapy unit, department of Rehabilitation last 3 years (January, 2014- December, 2016). The data consist of onset of symptom, range of motion and obtaining physical modalities were recorded. There was a statistically significant increase in shoulder flexion [mean difference 38.88 with 95%CI were [16.00-61.77], shoulder abduction [mean difference 48.47 with 95%CI were 16.07-90.59], shoulder internal rotation [mean difference 22.36 with 95%CI were 2.81-37.18] and shoulder external rotation [mean difference 32.12 with 95%CI were [(-2.47)-(46.91)]. In addition, the onset of symptom was 76.42±46.90 days. And the physical modalities used frequently were hot pack 14.8% and ultrasound diathermy 13.7%. In conclusion, the physiotherapy program including, hot pack and ultrasound diathermy seem to be useful for frozen shoulder. But onset of symptom is too long to start physiotherapy programs. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=frozen%20shoulder" title="frozen shoulder">frozen shoulder</a>, <a href="https://publications.waset.org/abstracts/search?q=range%20of%20motions" title=" range of motions"> range of motions</a>, <a href="https://publications.waset.org/abstracts/search?q=onset%20of%20symptom" title=" onset of symptom"> onset of symptom</a>, <a href="https://publications.waset.org/abstracts/search?q=physiotherapy" title=" physiotherapy"> physiotherapy</a>, <a href="https://publications.waset.org/abstracts/search?q=physical%20modality" title=" physical modality"> physical modality</a> </p> <a href="https://publications.waset.org/abstracts/76455/physiotherapy-program-for-frozen-shoulder-related-to-onset-of-symptom-range-of-motions-and-obtaining-modalities" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/76455.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">285</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3035</span> Aristotle&#039;s Notion of Akratic Action through the Prism of Moral Psychology</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Manik%20Konch">Manik Konch</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Actions are generally evaluated from moral point of view. Either the action is praised or condemned, but in all cases it involves the agent who performs it. The agent is held morally responsible for bringing out an action. This paper is an attempt to explore the Aristotle’s notion of action and its relation with moral development in response to modern philosophical moral psychology. Particularly, the distinction between voluntary, involuntary, and non-voluntary action in the Nicomachean Ethics with some basic problems from the perspective of moral psychology: the role of choice, moral responsibility, desire, and akrasia for an action. How to do a morally right action? Is there any role of virtue, character to do a moral action? These problems are analyzed and interpreted in order to show that the Aristotelian theory of action significantly contributes to the philosophical study of moral psychology. In this connection, the paper juxtaposes Aristotle’s theory of action with response from David Charles, John R. Searle’s, and Alfred Mele theorization of action in the mechanism of human moral behaviours. To achieve this addressed problem, we consider, how the recent moral philosophical moral psychology research can shed light on Aristotle's ethics by focusing on theory of action. In this connection, we argue that the desire is the only responsible for the akratic action. According to Aristotle, desire is primary source of action and it is the starting point of action and also the endpoint of an action. Therefore we are trying to see how desire can make a person incontinent and motivate to do such irrational actions. Is there any causes which we can say such actions are right or wrong? To measure an action we have need to see the consequences such act. Thus, we discuss the relationship between akrasia and action from the perspective of contemporary moral psychologists and philosophers whose are currently working on it. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=action" title="action">action</a>, <a href="https://publications.waset.org/abstracts/search?q=desire" title=" desire"> desire</a>, <a href="https://publications.waset.org/abstracts/search?q=moral%20psychology" title=" moral psychology"> moral psychology</a>, <a href="https://publications.waset.org/abstracts/search?q=Aristotle" title=" Aristotle"> Aristotle</a> </p> <a href="https://publications.waset.org/abstracts/55260/aristotles-notion-of-akratic-action-through-the-prism-of-moral-psychology" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/55260.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">260</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3034</span> The Application of Action Research to Integrate the Innovation in Learning Experience in a Design Course</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Walaa%20Mohammed%20Metwally">Walaa Mohammed Metwally</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This case study used the action research concept as a tool to integrate the innovation in a learning experience on a design course. The action research was investigated at Prince Sultan University, College of Engineering in the Interior Design and Architecture Department in January 2015, through the Higher Education Academy program. The action research was presented first with the definition of the research, leading to how it was used and how solutions were found. It concluded by showing that once the action research application in interior design and architecture were studied it was an effective tool to improve student&rsquo;s learning, develop their practice in design courses, and it discussed the negative and positive issues that were encountered. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=action%20research" title="action research">action research</a>, <a href="https://publications.waset.org/abstracts/search?q=innovation" title=" innovation"> innovation</a>, <a href="https://publications.waset.org/abstracts/search?q=intervention" title=" intervention"> intervention</a>, <a href="https://publications.waset.org/abstracts/search?q=learning%20experience" title=" learning experience"> learning experience</a>, <a href="https://publications.waset.org/abstracts/search?q=peer%20review" title=" peer review"> peer review</a> </p> <a href="https://publications.waset.org/abstracts/41285/the-application-of-action-research-to-integrate-the-innovation-in-learning-experience-in-a-design-course" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/41285.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">339</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3033</span> Throughflow Effects on Thermal Convection in Variable Viscosity Ferromagnetic Liquids</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=G.%20N.%20Sekhar">G. N. Sekhar</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20G.%20Siddheshwar"> P. G. Siddheshwar</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20Jayalatha"> G. Jayalatha</a>, <a href="https://publications.waset.org/abstracts/search?q=R.%20Prakash"> R. Prakash</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The problem of thermal convection in temperature and magnetic field sensitive Newtonian ferromagnetic liquid is studied in the presence of uniform vertical magnetic field and throughflow. Using a combination of Galerkin and shooting techniques the critical eigenvalues are obtained for stationary mode. The effect of Prandtl number (Pr &gt; 1) on onset is insignificant and nonlinearity of non-buoyancy magnetic parameter M3 is found to have no influence on the onset of ferroconvection. The magnetic buoyancy number, M1 and variable viscosity parameter, V have destabilizing influences on the system. The effect of throughflow Peclet number, Pe is to delay the onset of ferroconvection and this effect is independent of the direction of flow. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ferroconvection" title="ferroconvection">ferroconvection</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20field%20dependent%20viscosity" title=" magnetic field dependent viscosity"> magnetic field dependent viscosity</a>, <a href="https://publications.waset.org/abstracts/search?q=temperature%20dependent%20viscosity" title=" temperature dependent viscosity"> temperature dependent viscosity</a>, <a href="https://publications.waset.org/abstracts/search?q=throughflow" title=" throughflow"> throughflow</a> </p> <a href="https://publications.waset.org/abstracts/71149/throughflow-effects-on-thermal-convection-in-variable-viscosity-ferromagnetic-liquids" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/71149.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">265</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3032</span> Trajectories of Conduct Problems and Cumulative Risk from Early Childhood to Adolescence</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Leslie%20M.%20Gutman">Leslie M. Gutman</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Conduct problems (CP) represent a major dilemma, with wide-ranging and long-lasting individual and societal impacts. Children experience heterogeneous patterns of conduct problems; based on the age of onset, developmental course and related risk factors from around age 3. Early childhood represents a potential window for intervention efforts aimed at changing the trajectory of early starting conduct problems. Using the UK Millennium Cohort Study (n = 17,206 children), this study (a) identifies trajectories of conduct problems from ages 3 to 14 years and (b) assesses the cumulative and interactive effects of individual, family and socioeconomic risk factors from ages 9 months to 14 years. The same factors according to three domains were assessed, including child (i.e., low verbal ability, hyperactivity/inattention, peer problems, emotional problems), family (i.e., single families, parental poor physical and mental health, large family size) and socioeconomic (i.e., low family income, low parental education, unemployment, social housing). A cumulative risk score for the child, family, and socioeconomic domains at each age was calculated. It was then examined how the cumulative risk scores explain variation in the trajectories of conduct problems. Lastly, interactive effects among the different domains of cumulative risk were tested. Using group-based trajectory modeling, four distinct trajectories were found including a ‘low’ problem group and three groups showing childhood-onset conduct problems: ‘school-age onset’; ‘early-onset, desisting’; and ‘early-onset, persisting’. The ‘low’ group (57% of the sample) showed a low probability of conducts problems, close to zero, from 3 to 14 years. The ‘early-onset, desisting’ group (23% of the sample) demonstrated a moderate probability of CP in early childhood, with a decline from 3 to 5 years and a low probability thereafter. The ‘early-onset, persistent’ group (8%) followed a high probability of conduct problems, which declined from 11 years but was close to 70% at 14 years. In the ‘school-age onset’ group, 12% of the sample showed a moderate probability of conduct problems from 3 and 5 years, with a sharp increase by 7 years, increasing to 50% at 14 years. In terms of individual risk, all factors increased the likelihood of being in the childhood-onset groups compared to the ‘low’ group. For cumulative risk, the socioeconomic domain at 9 months and 3 years, the family domain at all ages except 14 years and child domain at all ages were found to differentiate childhood-onset groups from the ‘low’ group. Cumulative risk at 9 months and 3 years did not differentiate between the ‘school-onset’ group and ‘low’ group. Significant interactions were found between the domains for the ‘early-onset, desisting group’ suggesting that low levels of risk in one domain may buffer the effects of high risk in another domain. The implications of these findings for preventive interventions will be highlighted. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=conduct%20problems" title="conduct problems">conduct problems</a>, <a href="https://publications.waset.org/abstracts/search?q=cumulative%20risk" title=" cumulative risk"> cumulative risk</a>, <a href="https://publications.waset.org/abstracts/search?q=developmental%20trajectories" title=" developmental trajectories"> developmental trajectories</a>, <a href="https://publications.waset.org/abstracts/search?q=early%20childhood" title=" early childhood"> early childhood</a>, <a href="https://publications.waset.org/abstracts/search?q=adolescence" title=" adolescence"> adolescence</a> </p> <a href="https://publications.waset.org/abstracts/89082/trajectories-of-conduct-problems-and-cumulative-risk-from-early-childhood-to-adolescence" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/89082.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">251</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3031</span> Epileptic Seizure Onset Detection via Energy and Neural Synchronization Decision Fusion</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Marwa%20Qaraqe">Marwa Qaraqe</a>, <a href="https://publications.waset.org/abstracts/search?q=Muhammad%20Ismail"> Muhammad Ismail</a>, <a href="https://publications.waset.org/abstracts/search?q=Erchin%20Serpedin"> Erchin Serpedin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper presents a novel architecture for a patient-specific epileptic seizure onset detector using scalp electroencephalography (EEG). The proposed architecture is based on the decision fusion calculated from energy and neural synchronization related features. Specifically, one level of the detector calculates the condition number (CN) of an EEG matrix to evaluate the amount of neural synchronization present within the EEG channels. On a parallel level, the detector evaluates the energy contained in four EEG frequency subbands. The information is then fed into two independent (parallel) classification units based on support vector machines to determine the onset of a seizure event. The decisions from the two classifiers are then combined together according to two fusion techniques to determine a global decision. Experimental results demonstrate that the detector based on the AND fusion technique outperforms existing detectors with a sensitivity of 100%, detection latency of 3 seconds, while it achieves a 2:76 false alarm rate per hour. The OR fusion technique achieves a sensitivity of 100%, and significantly improves delay latency (0:17 seconds), yet it achieves 12 false alarms per hour. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=epilepsy" title="epilepsy">epilepsy</a>, <a href="https://publications.waset.org/abstracts/search?q=EEG" title=" EEG"> EEG</a>, <a href="https://publications.waset.org/abstracts/search?q=seizure%20onset" title=" seizure onset"> seizure onset</a>, <a href="https://publications.waset.org/abstracts/search?q=electroencephalography" title=" electroencephalography"> electroencephalography</a>, <a href="https://publications.waset.org/abstracts/search?q=neuron" title=" neuron"> neuron</a>, <a href="https://publications.waset.org/abstracts/search?q=detection" title=" detection"> detection</a> </p> <a href="https://publications.waset.org/abstracts/24040/epileptic-seizure-onset-detection-via-energy-and-neural-synchronization-decision-fusion" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/24040.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">477</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3030</span> Real Time Multi Person Action Recognition Using Pose Estimates</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aishrith%20Rao">Aishrith Rao</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Human activity recognition is an important aspect of video analytics, and many approaches have been recommended to enable action recognition. In this approach, the model is used to identify the action of the multiple people in the frame and classify them accordingly. A few approaches use RNNs and 3D CNNs, which are computationally expensive and cannot be trained with the small datasets which are currently available. Multi-person action recognition has been performed in order to understand the positions and action of people present in the video frame. The size of the video frame can be adjusted as a hyper-parameter depending on the hardware resources available. OpenPose has been used to calculate pose estimate using CNN to produce heap-maps, one of which provides skeleton features, which are basically joint features. The features are then extracted, and a classification algorithm can be applied to classify the action. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=human%20activity%20recognition" title="human activity recognition">human activity recognition</a>, <a href="https://publications.waset.org/abstracts/search?q=computer%20vision" title=" computer vision"> computer vision</a>, <a href="https://publications.waset.org/abstracts/search?q=pose%20estimates" title=" pose estimates"> pose estimates</a>, <a href="https://publications.waset.org/abstracts/search?q=convolutional%20neural%20networks" title=" convolutional neural networks"> convolutional neural networks</a> </p> <a href="https://publications.waset.org/abstracts/127872/real-time-multi-person-action-recognition-using-pose-estimates" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/127872.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">141</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3029</span> A Randomized Controlled Trial Study on the Effect of Adding Dexmedetomidine to Bupivacaine in Supraclavicular Block Using Ultrasound Guidance</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nazia%20Nazir">Nazia Nazir</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: The benefits of regional anesthetic techniques are well established. Use of additives to local anesthetics can prolong these benefits. The aim of this study was to observe the effect of adding dexmedetomidine to bupivacaine for the supraclavicular block. Methods (Design): In this randomized, double-blind study, seventy ASA I & II patients of either sex undergoing elective surgeries on the upper limb were given supraclavicular block under ultrasound guidance. Group C (n=35), received 38 mL 0.25% bupivacaine + 2mL normal saline and group D received 38 mL 0.25% bupivacaine + 1 µg/kg dexmedetomidine (2mL). Patients were observed for onset, duration of motor and sensory block, duration of analgesia, sedation score, hemodynamic changes and any adverse events. Results: In group D the onset was faster (P < 0.001), duration of sensory and motor block, as well as duration of analgesia, was prolonged as compared to group C (P < 0.0001). There was significant drop in heart rate (HR) from the baseline in group D (P < 0.05) at 30, 60, 90 and 120 min, however, none of the patients dropped HR below 50/min. Mean arterial Pressure (MAP) remained unaffected. The patients in group D were effectively sedated than those in group C (P < 0.05). No adverse event was reported in either group. Conclusion: Dexmedetomidine as adjuvant to bupivacaine in supraclavicular block resulted in faster action, prolonged motor and sensory block, prolonged analgesia with hemodynamic stability and adequate sedation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Analgesia" title="Analgesia">Analgesia</a>, <a href="https://publications.waset.org/abstracts/search?q=bupivacaine" title=" bupivacaine"> bupivacaine</a>, <a href="https://publications.waset.org/abstracts/search?q=dexmedetomidine" title=" dexmedetomidine"> dexmedetomidine</a>, <a href="https://publications.waset.org/abstracts/search?q=supraclavicular%20block" title=" supraclavicular block"> supraclavicular block</a> </p> <a href="https://publications.waset.org/abstracts/90335/a-randomized-controlled-trial-study-on-the-effect-of-adding-dexmedetomidine-to-bupivacaine-in-supraclavicular-block-using-ultrasound-guidance" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/90335.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">191</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3028</span> The Pressure Losses in the Model of Human Lungs</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Michaela%20Chovancova">Michaela Chovancova</a>, <a href="https://publications.waset.org/abstracts/search?q=Pavel%20Niedoba"> Pavel Niedoba</a> </p> <p class="card-text"><strong>Abstract:</strong></p> For the treatment of acute and chronic lung diseases it is preferred to deliver medicaments by inhalation. The drug is delivered directly to tracheobronchial tree. This way allows the given medicament to get directly into the place of action and it makes rapid onset of action and maximum efficiency. The transport of aerosol particles in the particular part of the lung is influenced by their size, anatomy of the lungs, breathing pattern and airway resistance. This article deals with calculation of airway resistance in the lung model of Horsfield. It solves the problem of determination of the pressure losses in bifurcation and thus defines the pressure drop at a given location in the bronchial tree. The obtained data will be used as boundary conditions for transport of aerosol particles in a central part of bronchial tree realized by Computational Fluid Dynamics (CFD) approach. The results obtained from CFD simulation will allow us to provide information on the required particle size and optimal inhalation technique for particle transport into particular part of the lung. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=human%20lungs" title="human lungs">human lungs</a>, <a href="https://publications.waset.org/abstracts/search?q=bronchial%20tree" title=" bronchial tree"> bronchial tree</a>, <a href="https://publications.waset.org/abstracts/search?q=pressure%20losses" title=" pressure losses"> pressure losses</a>, <a href="https://publications.waset.org/abstracts/search?q=airways%20resistance" title=" airways resistance"> airways resistance</a>, <a href="https://publications.waset.org/abstracts/search?q=flow" title=" flow"> flow</a>, <a href="https://publications.waset.org/abstracts/search?q=breathing" title=" breathing "> breathing </a> </p> <a href="https://publications.waset.org/abstracts/19141/the-pressure-losses-in-the-model-of-human-lungs" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/19141.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">356</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3027</span> Calculating Asphaltenes Precipitation Onset Pressure by Using Cardanol as Precipitation Inhibitor: A Strategy to Increment the Oil Well Production</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Camilo%20A.%20Guerrero-Martin">Camilo A. Guerrero-Martin</a>, <a href="https://publications.waset.org/abstracts/search?q=Erik%20Montes%20Paez"> Erik Montes Paez</a>, <a href="https://publications.waset.org/abstracts/search?q=Marcia%20C.%20K.%20Oliveira"> Marcia C. K. Oliveira</a>, <a href="https://publications.waset.org/abstracts/search?q=Jonathan%20Campos"> Jonathan Campos</a>, <a href="https://publications.waset.org/abstracts/search?q=Elizabete%20F.%20Lucas"> Elizabete F. Lucas</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Asphaltenes precipitation is considered as a formation damage problem, which can reduce the oil recovery factor. It fouls piping and surface installations, as well as cause serious flow assurance complications and decline oil well production. Therefore, researchers have shown an interest in chemical treatments to control this phenomenon. The aim of this paper is to assess the asphaltenes precipitation onset of crude oils in the presence of cardanol, by titrating the crude with n-heptane. Moreover, based on this results obtained at atmosphere pressure, the asphaltenes precipitation onset pressure were calculated to predict asphaltenes precipitation in the reservoir, by using differential liberation and refractive index data of the oils. The influence of cardanol concentrations in the asphaltenes stabilization of three Brazilian crude oils samples (with similar API densities) was studied. Therefore, four formulations of cardanol in toluene were prepared: 0, 3, 5, 10 and 15 m/m%. The formulations were added to the crude at 2:98 ratio. The petroleum samples were characterized by API density, elemental analysis and differential liberation test. The asphaltenes precipitation onset (APO) was determined by titrating with n-heptane and monitoring with near-infrared (NIR). UV-Vis spectroscopy experiments were also done to assess the precipitate asphaltenes content. The asphaltenes precipitation envelopes (APE) were also determined by numerical simulation (Multiflash). In addition, the adequate artificial lift systems (ALS) for the oils were selected. It was based on the downhole well profile and a screening methodology. Finally, the oil flowrates were modelling by NODAL analysis production system in the PIPESIM software. The results of this study show that the asphaltenes precipitation onset of the crude oils were 2.2, 2.3 and 6.0 mL of n-heptane/g of oil. The cardanol was an effective inhibitor of asphaltenes precipitation for the crude oils used in this study, since it displaces the precipitation pressure of the oil to lower values. This indicates that cardanol can increase the oil wells productivity. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=asphaltenes" title="asphaltenes">asphaltenes</a>, <a href="https://publications.waset.org/abstracts/search?q=NODAL%20analysis%20production%20system" title=" NODAL analysis production system"> NODAL analysis production system</a>, <a href="https://publications.waset.org/abstracts/search?q=precipitation%20pressure%20onset" title=" precipitation pressure onset"> precipitation pressure onset</a>, <a href="https://publications.waset.org/abstracts/search?q=inhibitory%20molecule" title=" inhibitory molecule"> inhibitory molecule</a> </p> <a href="https://publications.waset.org/abstracts/83321/calculating-asphaltenes-precipitation-onset-pressure-by-using-cardanol-as-precipitation-inhibitor-a-strategy-to-increment-the-oil-well-production" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/83321.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">175</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3026</span> Effects of Different Kinds of Combined Action Observation and Motor Imagery on Improving Golf Putting Performance and Learning</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Chi%20H.%20Lin">Chi H. Lin</a>, <a href="https://publications.waset.org/abstracts/search?q=Chi%20C.%20Lin"> Chi C. Lin</a>, <a href="https://publications.waset.org/abstracts/search?q=Chih%20L.%20Hsieh"> Chih L. Hsieh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Motor Imagery (MI) alone or combined with action observation (AO) has been shown to enhance motor performance and skill learning. The most effective way to combine these techniques has received limited scientific scrutiny. In the present study, we examined the effects of simultaneous (i.e., observing an action whilst imagining carrying out the action concurrently), alternate (i.e., observing an action and then doing imagery related to that action consecutively) and synthesis (alternately perform action observation and imagery action and then perform observation and imagery action simultaneously) AOMI combinations on improving golf putting performance and learning. Participants, 45 university students who had no formal experience of using imagery for the study, were randomly allocated to one of four training groups: simultaneous action observation and motor imagery (S-AOMI), alternate action observation and motor imagery (A-AOMI), synthesis action observation and motor imagery (A-S-AOMI), and a control group. And it was applied 'Different Experimental Groups with Pre and Post Measured' designs. Participants underwent eighteen times of different interventions, which were happened three times a week and lasting for six weeks. We analyzed the information we received based on two-factor (group × times) mixed between and within analysis of variance to discuss the real effects on participants' golf putting performance and learning about different intervention methods of different types of combined action observation and motor imagery. After the intervention, we then used imagery questionnaire and journey to understand the condition and suggestion about different motor imagery and action observation intervention from the participants. The results revealed that the three experimental groups both are effective in putting performance and learning but not for the control group, and the A-S-AOMI group is significantly better effect than S-AOMI group on golf putting performance and learning. The results confirmed the effect of motor imagery combined with action observation on the performance and learning of golf putting. In particular, in the groups of synthesis, motor imagery, or action observation were alternately performed first and then performed motor imagery, and action observation simultaneously would have the best effectiveness. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=motor%20skill%20learning" title="motor skill learning">motor skill learning</a>, <a href="https://publications.waset.org/abstracts/search?q=motor%20imagery" title=" motor imagery"> motor imagery</a>, <a href="https://publications.waset.org/abstracts/search?q=action%20observation" title=" action observation"> action observation</a>, <a href="https://publications.waset.org/abstracts/search?q=simulation" title=" simulation"> simulation</a> </p> <a href="https://publications.waset.org/abstracts/128207/effects-of-different-kinds-of-combined-action-observation-and-motor-imagery-on-improving-golf-putting-performance-and-learning" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/128207.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">138</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3025</span> A High Performance Piano Note Recognition Scheme via Precise Onset Detection and Segmented Short-Time Fourier Transform</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sonali%20Banrjee">Sonali Banrjee</a>, <a href="https://publications.waset.org/abstracts/search?q=Swarup%20Kumar%20Mitra"> Swarup Kumar Mitra</a>, <a href="https://publications.waset.org/abstracts/search?q=Aritra%20Acharyya"> Aritra Acharyya</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A piano note recognition method has been proposed by the authors in this paper. The authors have used a comprehensive method for onset detection of each note present in a piano piece followed by segmented short-time Fourier transform (STFT) for the identification of piano notes. The performance evaluation of the proposed method has been carried out in different harsh noisy environments by adding different levels of additive white Gaussian noise (AWGN) having different signal-to-noise ratio (SNR) in the original signal and evaluating the note detection error rate (NDER) of different piano pieces consisting of different number of notes at different SNR levels. The NDER is found to be remained within 15% for all piano pieces under consideration when the SNR is kept above 8 dB. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=AWGN" title="AWGN">AWGN</a>, <a href="https://publications.waset.org/abstracts/search?q=onset%20detection" title=" onset detection"> onset detection</a>, <a href="https://publications.waset.org/abstracts/search?q=piano%20note" title=" piano note"> piano note</a>, <a href="https://publications.waset.org/abstracts/search?q=STFT" title=" STFT"> STFT</a> </p> <a href="https://publications.waset.org/abstracts/96023/a-high-performance-piano-note-recognition-scheme-via-precise-onset-detection-and-segmented-short-time-fourier-transform" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/96023.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">160</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3024</span> The Evaluation of Superiority of Foot Local Anesthesia Method in Dairy Cows</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Samaneh%20Yavari">Samaneh Yavari</a>, <a href="https://publications.waset.org/abstracts/search?q=Christiane%20Pferrer"> Christiane Pferrer</a>, <a href="https://publications.waset.org/abstracts/search?q=Elisabeth%20Engelke"> Elisabeth Engelke</a>, <a href="https://publications.waset.org/abstracts/search?q=Alexander%20Starke"> Alexander Starke</a>, <a href="https://publications.waset.org/abstracts/search?q=Juergen%20Rehage"> Juergen Rehage</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Nowadays, bovine limb interventions, especially any claw surgeries, raises selection of the most qualified and appropriate local anesthesia technique applicable for any superficial or deep interventions of the limbs. Currently, two local anesthesia methods of Intravenous Regional Anesthesia (IVRA), as well as Nerve Blocks, have been routine to apply. However, the lack of studies investigating the quality and duration as well as quantity and onset of full (complete) local anesthesia, is noticeable. Therefore, the aim of our study was comparing the onset and quality of both IVRA and our modified NBA at the hind limb of dairy cows. For this abstract, only the onset of full local anesthesia would be consider. Materials and Methods: For that reason, we used six healthy non pregnant non lactating Holestein Frisian cows in a cross-over study design. Those cows divided into two groups to receive IVRA and our modified four-point NBA. For IVRA, 20 ml procaine without epinephrine was injected into the vein digitalis dorsalis communis III and for our modified four-point NBA, 10-15 ml procaine without epinephrine preneurally to the nerves, superficial and deep peroneal as well as lateral and medial branches of metatarsal nerves. For pain stimulation, electrical stimulator Grass S48 was applied. Results: The results of electrical stimuli revealed the faster onset of full local anesthesia (p < 0.05) by application of our modified NBA in comparison to IVRA about 10 minutes. Conclusion and discussion: Despite of available references showing faster onset of foot local anesthesia of IVRA, our study demonstrated that our modified four point NBA not only can be well known as a standard foot local anesthesia method applicable to desensitize the hind limb of dairy cows, but also, selection of this modified validated local anesthesia method can lead to have a faster start of complete desensitization of distal hind limb that is remarkable in any bovine limb interventions under time constraint. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=IVRA" title="IVRA">IVRA</a>, <a href="https://publications.waset.org/abstracts/search?q=four%20point%20NBA" title=" four point NBA"> four point NBA</a>, <a href="https://publications.waset.org/abstracts/search?q=dairy%20cow" title=" dairy cow"> dairy cow</a>, <a href="https://publications.waset.org/abstracts/search?q=hind%20limb" title=" hind limb"> hind limb</a>, <a href="https://publications.waset.org/abstracts/search?q=full%20onset" title=" full onset"> full onset</a> </p> <a href="https://publications.waset.org/abstracts/88288/the-evaluation-of-superiority-of-foot-local-anesthesia-method-in-dairy-cows" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/88288.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">151</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3023</span> Parsonage Turner Syndrome PTS, Case Report</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=A.%20M.%20Bumbea">A. M. Bumbea</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Musetescu"> A. Musetescu</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20Ciurea"> P. Ciurea</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Bighea"> A. Bighea</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objectives: The authors present a Parsonage Turner syndrome, a rare disease characterized by onset in apparently healthy person with shoulder and/or arm pain, sensory deficit, motor deficit. The causes are not established, could be determinate by vaccination, postoperative, immunologic disease, post traumatic etc. Methods: The authors present a woman case, 32 years old, (in 2006), no medical history, with arm pain and no other symptom. The onset was sudden with pain at very high level quantified as 10 to a 0 to 10 scale, with no response to classical analgesic and corticoids. The only drugs which can reduce the intensity of pain were oxycodone hydrochloride, 60 mg daily and pregabalinum150 mg daily. After two weeks the intensity of pain was reduced to 5. The patient started a rehabilitation program. After 6 weeks the patient associated sensory and motor deficit. We performed electromyography for upper limb that showed incomplete denervation with reduced neural transmission speed. The patient receives neurotrophic drugs and painkillers for a long period and physical and kinetic therapy. After 6 months the pain was reduced to level 2 and the patient maintained only 150 mg pregabalinum for another 6 months. Then, the evaluation showed no pain but general amiotrophy in upper limb. Results: At the evaluation in 2009, the patient developed a rheumatoid syndrome with tender and swelling joints, but no positive inflammation test, no antibodies or rheumatoid factor. After two years, in 2011 the patient develops an increase of antinuclear antibodies. This context certifies the diagnosis of lupus and the patient receives the specific therapy. Conclusions: This case is not a typical case of onset of lupus with PTS, but the onset of PTS could include the onset of an immune disease. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=lupus" title="lupus">lupus</a>, <a href="https://publications.waset.org/abstracts/search?q=arm%20pain" title=" arm pain"> arm pain</a>, <a href="https://publications.waset.org/abstracts/search?q=patient" title=" patient"> patient</a>, <a href="https://publications.waset.org/abstracts/search?q=swelling" title=" swelling "> swelling </a> </p> <a href="https://publications.waset.org/abstracts/27653/parsonage-turner-syndrome-pts-case-report" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/27653.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">330</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3022</span> Role of Apolipoprotein E Polymorphism on the Onset of Inflammatory Bowel Disease in Saudi Patients</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ebtissam%20Saleh%20Al-Meghaiseeb">Ebtissam Saleh Al-Meghaiseeb</a>, <a href="https://publications.waset.org/abstracts/search?q=Abdulaziz%20Al%20Masood"> Abdulaziz Al Masood</a>, <a href="https://publications.waset.org/abstracts/search?q=Abdulrahman%20Al-Robayan"> Abdulrahman Al-Robayan</a>, <a href="https://publications.waset.org/abstracts/search?q=Reem%20Al-Amro"> Reem Al-Amro</a>, <a href="https://publications.waset.org/abstracts/search?q=Misbahul%20Arfin"> Misbahul Arfin</a>, <a href="https://publications.waset.org/abstracts/search?q=Abdulrahman%20Al%20Asmari"> Abdulrahman Al Asmari</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective: The objective of this study was to evaluate the role of apolipoprotein E (APOE) polymorphism on the onset of inflammatory bowel disease (IBD) in Saudi patients. Methods: APOE gene was genotyped to evaluate the frequencies of the alleles and genotypes in Saudi subjects, including IBD patients (n=200) and matched controls (n=200), using APOE StripAssayTM kit (ViennaLab Labordiagnostika GmbH, Vienna, Austria). Results: The frequencies of alleles and genotypes of APOE differed in patients and controls. The APOE allele ε2 and ε4, genotype ε2/ε3 and ε2/ε4 were significantly higher in the IBD patients than the healthy controls. The frequencies of ε3 allele and ε3/ε3 genotype were higher in the control group as compared to patients. The higher prevalence of allele ε2 and ε4 allele in patients compared to that in controls suggested that ε2 and ε4 alleles may increase the risk of IBD. Results also indicated that APOE ε4 allele was associated with early age at onset of IBD. On the other hand, the decreased frequencies of ε3 allele and ε3/ε3 genotype in patients as compared to those in the controls suggested a protective effect of APOE ε3 for IBD susceptibility. In this study, the frequency distribution of APOE alleles and genotypes was not affected by the gender or type of IBD (familial or sporadic). Conclusion: This study indicates that APOE polymorphism plays a significant role in developing IBD and early age of onset in Saudi patients. However, further studies with large-size sample are warranted to confirm this relationship. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=APOE" title="APOE">APOE</a>, <a href="https://publications.waset.org/abstracts/search?q=polymorphism" title=" polymorphism"> polymorphism</a>, <a href="https://publications.waset.org/abstracts/search?q=IBD" title=" IBD"> IBD</a>, <a href="https://publications.waset.org/abstracts/search?q=saudis" title=" saudis"> saudis</a> </p> <a href="https://publications.waset.org/abstracts/156209/role-of-apolipoprotein-e-polymorphism-on-the-onset-of-inflammatory-bowel-disease-in-saudi-patients" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/156209.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">112</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3021</span> Third Language Perception of English Initial Plosives by Mandarin-Japanese Bilinguals</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rika%20Aoki">Rika Aoki</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of this paper is to investigate whether being bilinguals facilitates or impedes the perception of a third language. The present study conducted a perception experiment in which Mandarin-Japanese bilinguals categorized a Voice-Onset-Time (VOT) continuum into English /b/ or /p/. The results show that early bilinguals were influenced by both Mandarin and Japanese, while late bilinguals behaved in a similar manner to Mandarin monolinguals Thus, it can be concluded that in the present study having two languages did not help bilinguals to perceive L3 stop contrast native-likely. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bilinguals" title="bilinguals">bilinguals</a>, <a href="https://publications.waset.org/abstracts/search?q=perception" title=" perception"> perception</a>, <a href="https://publications.waset.org/abstracts/search?q=third%20language%20acquisition" title=" third language acquisition"> third language acquisition</a>, <a href="https://publications.waset.org/abstracts/search?q=voice-onset-time" title=" voice-onset-time"> voice-onset-time</a> </p> <a href="https://publications.waset.org/abstracts/58788/third-language-perception-of-english-initial-plosives-by-mandarin-japanese-bilinguals" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/58788.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">292</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3020</span> Changes in the fecal Microbiome of Periparturient Dairy Cattle and Associations with the Onset of Salmonella Shedding</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Lohendy%20Munoz-Vargas">Lohendy Munoz-Vargas</a>, <a href="https://publications.waset.org/abstracts/search?q=Stephen%20O.%20Opiyo"> Stephen O. Opiyo</a>, <a href="https://publications.waset.org/abstracts/search?q=Rose%20Digianantonio"> Rose Digianantonio</a>, <a href="https://publications.waset.org/abstracts/search?q=Michele%20L.%20Williams"> Michele L. Williams</a>, <a href="https://publications.waset.org/abstracts/search?q=Asela%20Wijeratne"> Asela Wijeratne</a>, <a href="https://publications.waset.org/abstracts/search?q=Gregory%20Habing"> Gregory Habing</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Non-typhoidal Salmonella enterica is a zoonotic pathogen with critical importance in animal and public health. The persistence of Salmonella on farms affects animal productivity and health, and represents a risk for food safety. The intestinal microbiota plays a fundamental role in the colonization and invasion of this ubiquitous microorganism. To overcome the colonization resistance imparted by the gut microbiome, Salmonella uses invasion strategies and the host inflammatory response to survive, proliferate, and establish infections with diverse clinical manifestations. Cattle serve as reservoirs of Salmonella, and periparturient cows have high prevalence of Salmonella shedding; however, to author`s best knowledge, little is known about the association between the gut microbiome and the onset of Salmonella shedding during the periparturient period. Thus, the objective of this study was to assess the association between changes in bacterial communities and the onset of Salmonella shedding in cattle approaching parturition. In a prospective cohort study, fecal samples from 98 dairy cows originating from four different farms were collected at four time points relative to calving (-3 wks, -1 wk, +1 wk, +3 wks). All 392 samples were cultured for Salmonella. Sequencing of the V4 region of the 16S rRNA gene using the Illumina platform was completed to evaluate the fecal microbiome in a selected sample subset. Analyses of microbial composition, diversity, and structure were performed according to time points, farm, and Salmonella onset status. Individual cow fecal microbiomes, predominated by Bacteroidetes, Firmicutes, Spirochaetes, and Proteobacteria phyla, significantly changed before and after parturition. Microbial communities from different farms were distinguishable based on multivariate analysis. Although there were significant differences in some bacterial taxa between Salmonella positive and negative samples, our results did not identify differences in the fecal microbial diversity or structure for cows with and without the onset of Salmonella shedding. These data suggest that determinants other than the significant changes in the fecal microbiome influence the periparturient onset of Salmonella shedding in dairy cattle. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=dairy%20cattle" title="dairy cattle">dairy cattle</a>, <a href="https://publications.waset.org/abstracts/search?q=microbiome" title=" microbiome"> microbiome</a>, <a href="https://publications.waset.org/abstracts/search?q=periparturient" title=" periparturient"> periparturient</a>, <a href="https://publications.waset.org/abstracts/search?q=Salmonella" title=" Salmonella"> Salmonella</a> </p> <a href="https://publications.waset.org/abstracts/95942/changes-in-the-fecal-microbiome-of-periparturient-dairy-cattle-and-associations-with-the-onset-of-salmonella-shedding" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/95942.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">173</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3019</span> The Effect of Low Power Laser on CK and Some of Markers Delayed Onset Muscle Soreness (DOMS)</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bahareh%20Yazdanparast%20Chaharmahali">Bahareh Yazdanparast Chaharmahali</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The study showed effect of low power laser therapy on knee range of motion (flexion and extension), resting angle of knee joint, knee circumference and rating of delayed onset muscle soreness induced pain, 24 and 48 hours after eccentric training of knee flexor muscle (hamstring muscle). We investigate the effects of pulsed ultrasound on swelling, relaxed, flexion and extension knee angle and pain. 20 volunteers among girl students of college voluntary participated in this research. After eccentric training, subjects were randomly divided into two groups, control and laser therapy. In day 1 and in order to induce delayed onset muscle soreness, subjects eccentrically trained their knee flexor muscles. In day 2, subjects were randomly divided into two groups: control and low power laser therapy. 24 and 48 hours after eccentric training. Variables (knee flexion and extension, srang of motion, resting knee joint angle and knee circumferences) were measured and analyzed. Data are reported as means ± standard error (SE) and repeated measured was used to assess differences within groups. Methods of treatment (low power laser therapy) have significant effects on delayed onset muscle soreness markers. 24 and 48 hours after training a significant difference was observed between mean pains of 2 groups. This difference was significant between low power laser therapy and C groups. The Bonferroni post hock is significant. Low power laser therapy trophy as used in this study did significantly diminish the effects of delayed – onset muscle soreness on swelling, relaxed – knee extension and flexion angle. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=creatine%20kinase" title="creatine kinase">creatine kinase</a>, <a href="https://publications.waset.org/abstracts/search?q=DOMS" title=" DOMS"> DOMS</a>, <a href="https://publications.waset.org/abstracts/search?q=eccentric%20training" title=" eccentric training"> eccentric training</a>, <a href="https://publications.waset.org/abstracts/search?q=low%20power%20laser" title=" low power laser"> low power laser</a> </p> <a href="https://publications.waset.org/abstracts/50388/the-effect-of-low-power-laser-on-ck-and-some-of-markers-delayed-onset-muscle-soreness-doms" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/50388.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">246</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3018</span> Soret-Driven Convection in a Binary Fluid with Coriolis Force</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=N.%20H.%20Z.%20Abidin">N. H. Z. Abidin</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20F.%20M.%20Mokhtar"> N. F. M. Mokhtar</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20S.%20A.%20Gani"> S. S. A. Gani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The influence of diffusion of the thermal or known as Soret effect in a heated Binary fluid model with Coriolis force is investigated theoretically. The linear stability analysis is used, and the eigenvalue is obtained using the Galerkin method. The impact of the Soret and Coriolis force on the onset of stationary convection in a system is analysed with respect to various Binary fluid parameters and presented graphically. It is found that an increase of the Soret values, destabilize the Binary fluid layer system. However, elevating the values of the Coriolis force helps to lag the onset of convection in a system. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Benard%20convection" title="Benard convection">Benard convection</a>, <a href="https://publications.waset.org/abstracts/search?q=binary%20fluid" title=" binary fluid"> binary fluid</a>, <a href="https://publications.waset.org/abstracts/search?q=Coriolis" title=" Coriolis"> Coriolis</a>, <a href="https://publications.waset.org/abstracts/search?q=Soret" title=" Soret "> Soret </a> </p> <a href="https://publications.waset.org/abstracts/68076/soret-driven-convection-in-a-binary-fluid-with-coriolis-force" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/68076.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">386</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3017</span> Identification of microRNAs in Early and Late Onset of Parkinson’s Disease Patient</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ahmad%20Rasyadan%20Arshad">Ahmad Rasyadan Arshad</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Rahman%20A.%20Jamal"> A. Rahman A. Jamal</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Mohamed%20Ibrahim"> N. Mohamed Ibrahim</a>, <a href="https://publications.waset.org/abstracts/search?q=Nor%20Azian%20Abdul%20Murad"> Nor Azian Abdul Murad</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Parkinson’s disease (PD) is a complex and asymptomatic disease where patients are usually diagnosed at late stage where about 70% of the dopaminergic neurons are lost. Therefore, identification of molecular biomarkers is crucial for early diagnosis of PD. MicroRNA (miRNA) is a short nucleotide non-coding small RNA which regulates the gene expression in post-translational process. The involvement of these miRNAs in neurodegenerative diseases includes maintenance of neuronal development, necrosis, mitochondrial dysfunction and oxidative stress. Thus, miRNA could be a potential biomarkers for diagnosis of PD. Objective: This study aim to identify the miRNA involved in Late Onset PD (LOPD) and Early Onset PD (EOPD) compared to the controls. Methods: This is a case-control study involved PD patients in the Chancellor Tunku Muhriz Hospital at the UKM Medical Centre. miRNA samples were extracted using miRNeasy serum/plasma kit from Qiagen. The quality of miRNA extracted was determined using Agilent RNA 6000 Nano kit in the Bioanalyzer. miRNA expression was performed using GeneChip miRNA 4.0 chip from Affymetrix. Microarray was performed in EOPD (n= 7), LOPD (n=9) and healthy control (n=11). Expression Console and Transcriptomic Analyses Console were used to analyze the microarray data. Result: miR-129-5p was significantly downregulated in EOPD compared to LOPD with -4.2 fold change (p = <0.050. miR-301a-3p was upregulated in EOPD compared to healthy control (fold = 10.3, p = <0.05). In LOPD versus healthy control, miR-486-3p (fold = 15.28, p = <0.05), miR-29c-3p (fold = 12.21, p = <0.05) and miR-301a-3p (fold = 10.01, p =< 0.05) were upregulated. Conclusion: Several miRNA have been identified to be differentially expressed in EOPD compared to LOPD and PD versus control. These miRNAs could serve as the potential biomarkers for early diagnosis of PD. However, these miRNAs need to be validated in a larger sample size. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=early%20onset%20PD" title="early onset PD">early onset PD</a>, <a href="https://publications.waset.org/abstracts/search?q=late%20onset%20PD" title=" late onset PD"> late onset PD</a>, <a href="https://publications.waset.org/abstracts/search?q=microRNA%20%28miRNA%29" title=" microRNA (miRNA)"> microRNA (miRNA)</a>, <a href="https://publications.waset.org/abstracts/search?q=microarray" title=" microarray"> microarray</a> </p> <a href="https://publications.waset.org/abstracts/58919/identification-of-micrornas-in-early-and-late-onset-of-parkinsons-disease-patient" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/58919.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">259</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3016</span> Effectiveness of Radon Remedial Action Implemented in a School on the Island of Ischia</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=F.%20Loffredo">F. Loffredo</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Quarto"> M. Quarto</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Pugliese"> M. Pugliese</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Mazzella"> A. Mazzella</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20De%20Cicco"> F. De Cicco</a>, <a href="https://publications.waset.org/abstracts/search?q=V.%20Roca"> V. Roca</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of this study is to evaluate the efficacy of radon remedial action in a school on the Ischia island, South Italy, affected by indoor radon concentration higher than the value of 500 Bq/m<sup>3</sup>. This value is the limit imposed by the Italian legislation, to above which corrective actions in schools are necessary. Before the application of remedial action, indoor radon concentrations were measured in 9 rooms of the school. The measurements were performed with LR-115 passive alpha detectors (SSNTDs) and E-Perm. The remedial action was conducted in one of the office affected by high radon concentration using a Radonstop paint applied after the construction of a concrete slab under the floor. The effect of remedial action was the reduction of the concentration of radon of 41% and moreover it has demonstrated to be durable over time. The chosen method is cheap and easy to apply and it could be designed for various types of building. This method can be applied to new and existing buildings that show high dose values. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=E-Perm" title="E-Perm">E-Perm</a>, <a href="https://publications.waset.org/abstracts/search?q=LR%20115%20detectors" title=" LR 115 detectors"> LR 115 detectors</a>, <a href="https://publications.waset.org/abstracts/search?q=radon%20remediation" title=" radon remediation"> radon remediation</a>, <a href="https://publications.waset.org/abstracts/search?q=school" title=" school"> school</a> </p> <a href="https://publications.waset.org/abstracts/67302/effectiveness-of-radon-remedial-action-implemented-in-a-school-on-the-island-of-ischia" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/67302.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">229</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3015</span> Rayleigh-Bénard-Taylor Convection of Newtonian Nanoliquid</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=P.%20G.%20Siddheshwar">P. G. Siddheshwar</a>, <a href="https://publications.waset.org/abstracts/search?q=T.%20N.%20Sakshath"> T. N. Sakshath</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In the paper we make linear and non-linear stability analyses of Rayleigh-B&eacute;nard convection of a Newtonian nanoliquid in a rotating medium (called as Rayleigh-B&eacute;nard-Taylor convection). Rigid-rigid isothermal boundaries are considered for investigation. Khanafer-Vafai-Lightstone single phase model is used for studying instabilities in nanoliquids. Various thermophysical properties of nanoliquid are obtained using phenomenological laws and mixture theory. The eigen boundary value problem is solved for the Rayleigh number using an analytical method by considering trigonometric eigen functions. We observe that the critical nanoliquid Rayleigh number is less than that of the base liquid. Thus the onset of convection is advanced due to the addition of nanoparticles. So, increase in volume fraction leads to advanced onset and thereby increase in heat transport. The amplitudes of convective modes required for estimating the heat transport are determined analytically. The tri-modal standard Lorenz model is derived for the steady state assuming small scale convective motions. The effect of rotation on the onset of convection and on heat transport is investigated and depicted graphically. It is observed that the onset of convection is delayed due to rotation and hence leads to decrease in heat transport. Hence, rotation has a stabilizing effect on the system. This is due to the fact that the energy of the system is used to create the component V. We observe that the amount of heat transport is less in the case of rigid-rigid isothermal boundaries compared to free-free isothermal boundaries. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=nanoliquid" title="nanoliquid">nanoliquid</a>, <a href="https://publications.waset.org/abstracts/search?q=rigid-rigid" title=" rigid-rigid"> rigid-rigid</a>, <a href="https://publications.waset.org/abstracts/search?q=rotation" title=" rotation"> rotation</a>, <a href="https://publications.waset.org/abstracts/search?q=single%20phase" title=" single phase"> single phase</a> </p> <a href="https://publications.waset.org/abstracts/69850/rayleigh-benard-taylor-convection-of-newtonian-nanoliquid" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/69850.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span 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