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id="siteSub" class="noprint">From Wikipedia, the free encyclopedia</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="en" dir="ltr"><style data-mw-deduplicate="TemplateStyles:r1236090951">.mw-parser-output .hatnote{font-style:italic}.mw-parser-output div.hatnote{padding-left:1.6em;margin-bottom:0.5em}.mw-parser-output .hatnote i{font-style:normal}.mw-parser-output .hatnote+link+.hatnote{margin-top:-0.5em}@media print{body.ns-0 .mw-parser-output .hatnote{display:none!important}}</style><div role="note" class="hatnote navigation-not-searchable">Not to be confused with <a href="/wiki/Intelligent_design" title="Intelligent design">Intelligent design</a>.</div> <style data-mw-deduplicate="TemplateStyles:r1251242444">.mw-parser-output .ambox{border:1px solid #a2a9b1;border-left:10px solid #36c;background-color:#fbfbfb;box-sizing:border-box}.mw-parser-output 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0.5em;text-align:center}.mw-parser-output .ambox .mbox-imageright{border:none;padding:2px 0.5em 2px 0;text-align:center}.mw-parser-output .ambox .mbox-empty-cell{border:none;padding:0;width:1px}.mw-parser-output .ambox .mbox-image-div{width:52px}@media(min-width:720px){.mw-parser-output .ambox{margin:0 10%}}@media print{body.ns-0 .mw-parser-output .ambox{display:none!important}}</style><table class="box-More_citations_needed plainlinks metadata ambox ambox-content ambox-Refimprove" role="presentation"><tbody><tr><td class="mbox-image"><div class="mbox-image-div"><span typeof="mw:File"><a href="/wiki/File:Question_book-new.svg" class="mw-file-description"><img alt="" src="//upload.wikimedia.org/wikipedia/en/thumb/9/99/Question_book-new.svg/50px-Question_book-new.svg.png" decoding="async" width="50" height="39" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/9/99/Question_book-new.svg/75px-Question_book-new.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/9/99/Question_book-new.svg/100px-Question_book-new.svg.png 2x" data-file-width="512" data-file-height="399" /></a></span></div></td><td class="mbox-text"><div class="mbox-text-span">This article <b>needs additional citations for <a href="/wiki/Wikipedia:Verifiability" title="Wikipedia:Verifiability">verification</a></b>.<span class="hide-when-compact"> Please help <a href="/wiki/Special:EditPage/Rational_design" title="Special:EditPage/Rational design">improve this article</a> by <a href="/wiki/Help:Referencing_for_beginners" title="Help:Referencing for beginners">adding citations to reliable sources</a>. Unsourced material may be challenged and removed.<br /><small><span class="plainlinks"><i>Find sources:</i> <a rel="nofollow" class="external text" href="https://www.google.com/search?as_eq=wikipedia&q=%22Rational+design%22">"Rational design"</a> – <a rel="nofollow" class="external text" href="https://www.google.com/search?tbm=nws&q=%22Rational+design%22+-wikipedia&tbs=ar:1">news</a> <b>·</b> <a rel="nofollow" class="external text" href="https://www.google.com/search?&q=%22Rational+design%22&tbs=bkt:s&tbm=bks">newspapers</a> <b>·</b> <a rel="nofollow" class="external text" href="https://www.google.com/search?tbs=bks:1&q=%22Rational+design%22+-wikipedia">books</a> <b>·</b> <a rel="nofollow" class="external text" href="https://scholar.google.com/scholar?q=%22Rational+design%22">scholar</a> <b>·</b> <a rel="nofollow" class="external text" href="https://www.jstor.org/action/doBasicSearch?Query=%22Rational+design%22&acc=on&wc=on">JSTOR</a></span></small></span> <span class="date-container"><i>(<span class="date">January 2019</span>)</i></span><span class="hide-when-compact"><i> (<small><a href="/wiki/Help:Maintenance_template_removal" title="Help:Maintenance template removal">Learn how and when to remove this message</a></small>)</i></span></div></td></tr></tbody></table> <p>In <a href="/wiki/Chemical_biology" title="Chemical biology">chemical biology</a> and <a href="/wiki/Biomolecular_engineering" title="Biomolecular engineering">biomolecular engineering</a>, <b>rational design</b> (<b>RD</b>) is an <a href="/wiki/Umbrella_term" class="mw-redirect" title="Umbrella term">umbrella term</a> which invites the strategy of creating new molecules with a certain functionality, based upon the ability to predict how the molecule's structure (specifically derived from <a href="/wiki/Structural_motif" title="Structural motif">motifs</a>) will affect its behavior through physical models. This can be done either from scratch or by making <a href="/wiki/Mathematical_model" title="Mathematical model">calculated variations</a> on a known structure, and usually complements <a href="/wiki/Directed_evolution" title="Directed evolution">directed evolution</a>. </p> <div class="mw-heading mw-heading2"><h2 id="Applications">Applications</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Rational_design&action=edit&section=1" title="Edit section: Applications"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>As an example, rational design is used to decipher <a href="/wiki/Collagen" title="Collagen">collagen</a> stability, mapping ligand-receptor interactions, unveiling protein folding and dynamics, and creating extra-biological structures by using fluorinated <a href="/wiki/Amino_acid" title="Amino acid">amino acids</a>.<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> To treat <a href="/wiki/Cancer" title="Cancer">cancer</a>, rational design is used for targeted therapies where proteins are engineered to modify the communication of cells with their environment.<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> There is also the rational design of alfa-alkyl <a href="/wiki/Auxin" title="Auxin">auxin</a> molecules, which are auxin analogs capable of binding and blocking the formation of the <a href="/wiki/Hormone_receptor" title="Hormone receptor">hormone receptor</a> complex.<sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> </p><p>Other applications of rational design include: </p> <ul><li><a href="/wiki/Protein_design" title="Protein design">Protein design</a></li> <li><a href="/wiki/Nucleic_acid_design" title="Nucleic acid design">Nucleic acid design</a></li> <li><a href="/wiki/Drug_design" title="Drug design">Drug design</a></li> <li><a href="/w/index.php?title=Pathway_design&action=edit&redlink=1" class="new" title="Pathway design (page does not exist)">Pathway design</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Rational_design&action=edit&section=2" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-1">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite id="CITEREFOjima2009" class="citation book cs1">Ojima, Iwao (2009). <i>Fluorine in Medicinal Chemistry and Chemical Biology</i>. West Sussex: John Wiley & Sons, Ltd., Publications. p. 411. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/9781405167208" title="Special:BookSources/9781405167208"><bdi>9781405167208</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Fluorine+in+Medicinal+Chemistry+and+Chemical+Biology&rft.place=West+Sussex&rft.pages=411&rft.pub=John+Wiley+%26+Sons%2C+Ltd.%2C+Publications&rft.date=2009&rft.isbn=9781405167208&rft.aulast=Ojima&rft.aufirst=Iwao&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARational+design" class="Z3988"></span></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-2">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFRichards-Kortum2010" class="citation book cs1">Richards-Kortum, Rebecca (2010). <i>Biomedical Engineering for Global Health</i>. Cambridge: Cambridge University Press. p. 178. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/9780521877978" title="Special:BookSources/9780521877978"><bdi>9780521877978</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Biomedical+Engineering+for+Global+Health&rft.place=Cambridge&rft.pages=178&rft.pub=Cambridge+University+Press&rft.date=2010&rft.isbn=9780521877978&rft.aulast=Richards-Kortum&rft.aufirst=Rebecca&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARational+design" class="Z3988"></span></span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-3">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFKombrinkKaiser2016" class="citation book cs1">Kombrink, Erich; Kaiser, Markus (2016). <i>When Chemistry Meets Biology – Generating Innovative Concepts, Methods and Tools for Scientific Discovery in the Plant Sciences</i>. Lausanne: Frontiers Media SA. p. 90. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/9782889199280" title="Special:BookSources/9782889199280"><bdi>9782889199280</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=When+Chemistry+Meets+Biology+%E2%80%93+Generating+Innovative+Concepts%2C+Methods+and+Tools+for+Scientific+Discovery+in+the+Plant+Sciences&rft.place=Lausanne&rft.pages=90&rft.pub=Frontiers+Media+SA&rft.date=2016&rft.isbn=9782889199280&rft.aulast=Kombrink&rft.aufirst=Erich&rft.au=Kaiser%2C+Markus&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARational+design" class="Z3988"></span></span> </li> </ol></div></div> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r1129693374">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output 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class="navbox-title" colspan="2"><div id="Disciplines" style="font-size:114%;margin:0 4em">Disciplines</div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Communication_design" title="Communication design">Communication<br />design</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Advertising" title="Advertising">Advertising</a></li> <li><a href="/wiki/Book_design" title="Book design">Book design</a></li> <li><a href="/wiki/Brand" title="Brand">Brand design</a></li> <li><a href="/wiki/Exhibit_design" title="Exhibit design">Exhibit design</a></li> <li><a href="/wiki/Film_title_design" title="Film title design">Film title design</a></li> <li><a href="/wiki/Graphic_design" title="Graphic design">Graphic design</a> <ul><li><a href="/wiki/Motion_graphic_design" title="Motion graphic design">Motion</a></li> <li><a href="/wiki/Postage_stamp_design" title="Postage stamp design">Postage stamp design</a></li> <li><a href="/wiki/Print_design" title="Print design">Print design</a></li></ul></li> <li><a href="/wiki/Illustration" title="Illustration">Illustration</a></li> <li><a href="/wiki/Information_design" title="Information design">Information design</a></li> <li><a href="/wiki/Instructional_design" title="Instructional design">Instructional design</a></li> <li><a href="/wiki/News_design" title="News design">News design</a></li> <li><a href="/wiki/Photography" title="Photography">Photography</a></li> <li><a href="/wiki/Retail_design" title="Retail design">Retail design</a></li> <li><a href="/wiki/Signage" title="Signage">Signage</a> / <a href="/wiki/Traffic_sign_design" title="Traffic sign design">Traffic sign design</a></li> <li><a href="/wiki/Typography" title="Typography">Typography</a> / <a href="/wiki/Type_design" title="Type design">Type design</a></li> <li><a href="/wiki/Video_design" title="Video design">Video design</a></li> <li><a href="/wiki/Visual_merchandising" title="Visual merchandising">Visual merchandising</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Environmental_design" title="Environmental design">Environmental<br />design</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Architecture" title="Architecture">Architecture</a></li> <li><a href="/wiki/Architectural_lighting_design" title="Architectural lighting design">Architectural lighting design</a></li> <li><a href="/wiki/Building_design" title="Building design">Building design</a> <ul><li><a href="/wiki/Passive_solar_building_design" title="Passive solar building design">Passive solar</a></li></ul></li> <li><a href="/wiki/Ecological_design" title="Ecological design">Ecological design</a></li> <li><a href="/wiki/Environmental_impact_design" title="Environmental impact design">Environmental impact design</a></li> <li><a href="/wiki/Garden_design" title="Garden design">Garden design</a> <ul><li><a href="/wiki/Computer-aided_garden_design" title="Computer-aided garden design">Computer-aided</a></li></ul></li> <li><a href="/wiki/Healthy_community_design" title="Healthy community design">Healthy community design</a></li> <li><a href="/wiki/Hotel_design" title="Hotel design">Hotel design</a></li> <li><a href="/wiki/Interior_architecture" title="Interior architecture">Interior architecture</a></li> <li><a href="/wiki/Interior_design" title="Interior design">Interior design</a> <ul><li><a href="/wiki/Experiential_interior_design" title="Experiential interior design">EID</a></li></ul></li> <li><a href="/wiki/Keyline_design" title="Keyline design">Keyline design</a></li> <li><a href="/wiki/Landscape_architecture" title="Landscape architecture">Landscape architecture</a> <ul><li><a href="/wiki/Sustainable_landscape_architecture" title="Sustainable landscape architecture">Sustainable</a></li></ul></li> <li><a href="/wiki/Landscape_design" title="Landscape design">Landscape design</a></li> <li><a href="/wiki/Spatial_design" title="Spatial design">Spatial design</a></li> <li><a href="/wiki/Urban_design" title="Urban design">Urban design</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Industrial_design" title="Industrial design">Industrial<br />design</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Automotive_design" title="Automotive design">Automotive design</a></li> <li><a href="/wiki/Automotive_suspension_design_process" title="Automotive suspension design process">Automotive suspension design</a></li> <li><a href="/wiki/CMF_design" title="CMF design">CMF design</a></li> <li><a href="/wiki/Corrugated_box_design" title="Corrugated box design">Corrugated box design</a></li> <li><a href="/wiki/Electric_guitar_design" title="Electric guitar design">Electric guitar design</a></li> <li><a href="/wiki/Furniture" title="Furniture">Furniture design</a> <ul><li><a href="/wiki/Sustainable_furniture_design" title="Sustainable furniture design">Sustainable</a></li></ul></li> <li><a href="/wiki/Hardware_interface_design" title="Hardware interface design">Hardware interface design</a></li> <li><a href="/wiki/Motorcycle_design" title="Motorcycle design">Motorcycle design</a></li> <li><a href="/wiki/Packaging_and_labeling" class="mw-redirect" title="Packaging and labeling">Packaging and labeling</a></li> <li><a href="/wiki/Photographic_lens_design" title="Photographic lens design">Photographic lens design</a></li> <li><a href="/wiki/Product_design" title="Product design">Product design</a></li> <li><a href="/wiki/Production_designer" title="Production designer">Production design</a></li> <li><a href="/wiki/Sensory_design" title="Sensory design">Sensory design</a></li> <li><a href="/wiki/Service_design" title="Service design">Service design</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Interaction_design" title="Interaction design">Interaction<br />design</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Experience_design" class="mw-redirect" title="Experience design">Experience design</a> <ul><li><a href="/wiki/Employee_experience_design" title="Employee experience design">EED</a></li></ul></li> <li><a href="/wiki/Game_design" title="Game design">Game design</a> <ul><li><a href="/wiki/Level_(video_games)" title="Level (video games)">Level design</a></li> <li><a href="/wiki/Video_game_design" title="Video game design">Video game design</a></li></ul></li> <li><a href="/wiki/Hardware_interface_design" title="Hardware interface design">Hardware interface design</a></li> <li><a href="/wiki/Icon_design" title="Icon design">Icon design</a></li> <li><a href="/wiki/Immersive_design" title="Immersive design">Immersive design</a></li> <li><a href="/wiki/Information_design" title="Information design">Information design</a></li> <li><a href="/wiki/Sonic_interaction_design" title="Sonic interaction design">Sonic interaction design</a></li> <li><a href="/wiki/User_experience_design" title="User experience design">User experience design</a></li> <li><a href="/wiki/User_interface_design" title="User interface design">User interface design</a></li> <li><a href="/wiki/Web_design" title="Web design">Web design</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other<br /><a href="/wiki/Applied_arts" title="Applied arts">applied arts</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Public_art" title="Public art">Public art design</a></li> <li><a href="/wiki/Ceramic_art" title="Ceramic art">Ceramic</a> / <a href="/wiki/Glass_art" title="Glass art">glass design</a></li> <li><a href="/wiki/Fashion_design" title="Fashion design">Fashion design</a> <ul><li><a href="/wiki/Costume_design" title="Costume design">Costume design</a></li> <li><a href="/wiki/Jewellery_design" title="Jewellery design">Jewellery design</a></li></ul></li> <li><a href="/wiki/Floral_design" title="Floral design">Floral design</a></li> <li><a href="/wiki/Game_art_design" title="Game art design">Game art design</a></li> <li><a href="/wiki/Property_designer" class="mw-redirect" title="Property designer">Property design</a></li> <li><a href="/wiki/Scenic_design" title="Scenic design">Scenic design</a></li> <li><a href="/wiki/Sound_design" title="Sound design">Sound design</a></li> <li><a href="/wiki/Lighting_design" title="Lighting design">Stage/set lighting design</a></li> <li><a href="/wiki/Textile_design" title="Textile design">Textile design</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other<br />design<br />& <a href="/wiki/Engineering" title="Engineering">engineering</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Algorithm_design" class="mw-redirect" title="Algorithm design">Algorithm design</a></li> <li><a href="/wiki/Behavioural_design" title="Behavioural design">Behavioural design</a></li> <li><a href="/wiki/Boiler_design" title="Boiler design">Boiler design</a></li> <li><a href="/wiki/Database_design" title="Database design">Database design</a></li> <li><a href="/wiki/Drug_design" title="Drug design">Drug design</a></li> <li><a href="/wiki/Electrical_system_design" title="Electrical system design">Electrical system design</a></li> <li><a href="/wiki/Design_of_experiments" title="Design of experiments">Experimental design</a></li> <li><a href="/wiki/Filter_design" title="Filter design">Filter design</a></li> <li><a href="/wiki/Geometric_design" title="Geometric design">Geometric design</a></li> <li><a href="/wiki/Work_design" title="Work design">Work design</a></li> <li><a href="/wiki/Integrated_circuit_design" title="Integrated circuit design">Integrated circuit design</a> <ul><li><a href="/wiki/Circuit_design" title="Circuit design">Circuit design</a></li> <li><a href="/wiki/Physical_design_(electronics)" title="Physical design (electronics)">Physical design</a></li> <li><a href="/wiki/Power_network_design_(IC)" title="Power network design (IC)">Power network design</a></li></ul></li> <li><a href="/wiki/Mechanism_design" title="Mechanism design">Mechanism design</a></li> <li><a href="/wiki/Nuclear_weapon_design" title="Nuclear weapon design">Nuclear weapon design</a></li> <li><a href="/wiki/Nucleic_acid_design" title="Nucleic acid design">Nucleic acid design</a></li> <li><a href="/wiki/Organizational_architecture" title="Organizational architecture">Organization design</a></li> <li><a href="/wiki/Process_design" title="Process design">Process design</a></li> <li><a href="/wiki/Processor_design" title="Processor design">Processor design</a></li> <li><a href="/wiki/Protein_design" title="Protein design">Protein design</a></li> <li><a href="/wiki/Research_design" title="Research design">Research design</a></li> <li><a href="/wiki/Social_design" title="Social design">Social design</a></li> <li><a href="/wiki/Software_design" title="Software design">Software design</a></li> <li><a href="/wiki/Spacecraft_design" title="Spacecraft design">Spacecraft design</a></li> <li><a href="/wiki/Strategic_design" title="Strategic design">Strategic design</a></li> <li><a href="/wiki/Systems_design" title="Systems design">Systems design</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><div id="Approaches" style="font-size:114%;margin:0 4em">Approaches</div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Activity-centered_design" title="Activity-centered design">Activity-centered</a></li> <li><a href="/wiki/Adaptive_web_design" title="Adaptive web design">Adaptive web</a></li> <li><a href="/wiki/Affective_design" title="Affective design">Affective</a></li> <li><a href="/wiki/Brainstorming" title="Brainstorming">Brainstorming</a></li> <li><a href="/wiki/Design_by_committee" title="Design by committee">By committee</a></li> <li><a href="/wiki/Design_by_contract" title="Design by contract">By contract</a></li> <li><a href="/wiki/C-K_theory" title="C-K theory">C-K theory</a></li> <li><a href="/wiki/Design_closure" title="Design closure">Closure</a></li> <li><a href="/wiki/Participatory_design" title="Participatory design">Co-design</a></li> <li><a href="/w/index.php?title=Concept-oriented_design&action=edit&redlink=1" class="new" title="Concept-oriented design (page does not exist)">Concept-oriented</a></li> <li><a href="/wiki/Configuration_design" title="Configuration design">Configuration</a></li> <li><a href="/wiki/Contextual_design" title="Contextual design">Contextual</a></li> <li><a href="/wiki/Continuous_design" title="Continuous design">Continuous</a></li> <li><a href="/wiki/Cradle-to-cradle_design" title="Cradle-to-cradle design">Cradle-to-cradle</a></li> <li><a href="/wiki/Creative_problem-solving" title="Creative problem-solving">Creative problem-solving</a></li> <li><a href="/wiki/Creativity_techniques" title="Creativity techniques">Creativity techniques</a></li> <li><a href="/wiki/Critical_design" title="Critical design">Critical</a> <ul><li><a href="/wiki/Design_fiction" title="Design fiction">Design fiction</a></li></ul></li> <li><a href="/wiki/Defensive_design" title="Defensive design">Defensive</a></li> <li><a href="/wiki/Design%E2%80%93bid%E2%80%93build" title="Design–bid–build">Design–bid–build</a></li> <li><a href="/wiki/Design%E2%80%93build" title="Design–build">Design–build</a> <ul><li><a href="/wiki/Architect-led_design%E2%80%93build" class="mw-redirect" title="Architect-led design–build">architect-led</a></li></ul></li> <li><a href="/wiki/Diffuse_design" title="Diffuse design">Diffuse</a></li> <li><a href="/wiki/Domain-driven_design" title="Domain-driven design">Domain-driven</a></li> <li><a href="/wiki/Ecological_design" title="Ecological design">Ecological design</a></li> <li><a href="/wiki/Energy_neutral_design" title="Energy neutral design">Energy neutral</a></li> <li><a href="/wiki/Engineering_design_process" title="Engineering design process">Engineering design process</a> <ul><li><a href="/wiki/Probabilistic_design" title="Probabilistic design">Probabilistic design</a></li></ul></li> <li><a href="/wiki/Error-tolerant_design" title="Error-tolerant design">Error-tolerant</a></li> <li><a href="/wiki/Fault-tolerant_design" class="mw-redirect" title="Fault-tolerant design">Fault-tolerant</a></li> <li><a href="/wiki/Framework-oriented_design" title="Framework-oriented design">Framework-oriented</a></li> <li><a href="/wiki/Design_for_assembly" title="Design for assembly">For assembly</a></li> <li><a href="/wiki/Behavioural_design" title="Behavioural design">For behaviour change</a></li> <li><a href="/wiki/Design_for_manufacturability" title="Design for manufacturability">For manufacturability</a></li> <li><a href="/wiki/Design_for_Six_Sigma" title="Design for Six Sigma">For Six Sigma</a></li> <li><a href="/wiki/Design_for_testing" title="Design for testing">For testing</a></li> <li><a href="/wiki/Design_for_X" title="Design for X">For X</a></li> <li><a href="/wiki/Functional_design" title="Functional design">Functional</a></li> <li><a href="/wiki/Generative_design" title="Generative design">Generative</a></li> <li><a href="/wiki/Geodesign" title="Geodesign">Geodesign</a></li> <li><a href="/wiki/Human-centered_design" title="Human-centered design">HCD</a></li> <li><a href="/wiki/High-level_design" title="High-level design">High-level</a></li> <li><a href="/wiki/Inclusive_design" title="Inclusive design">Inclusive</a></li> <li><a href="/wiki/Integrated_design" title="Integrated design">Integrated</a></li> <li><a href="/wiki/Integrated_topside_design" title="Integrated topside design">Integrated topside</a></li> <li><a href="/wiki/Intelligence-based_design" title="Intelligence-based design">Intelligence-based</a></li> <li><a href="/wiki/Iterative_design" title="Iterative design">Iterative</a></li> <li><a href="/wiki/KISS_principle" title="KISS principle">KISS principle</a></li> <li><a href="/wiki/Low-level_design" title="Low-level design">Low-level</a></li> <li><a href="/wiki/Metadesign" title="Metadesign">Metadesign</a></li> <li><a href="/wiki/Mind_map" title="Mind map">Mind mapping</a></li> <li><a href="/wiki/Modular_design" title="Modular design">Modular</a></li> <li><a href="/wiki/New_Wave_(design)" title="New Wave (design)">New Wave</a></li> <li><a href="/wiki/Object-oriented_design" class="mw-redirect" title="Object-oriented design">Object-oriented</a></li> <li><a href="/wiki/Open-design_movement" title="Open-design movement">Open</a></li> <li><a href="/wiki/Parametric_design" title="Parametric design">Parametric</a></li> <li><a href="/wiki/Participatory_design" title="Participatory design">Participatory</a></li> <li><a href="/wiki/Platform-based_design" title="Platform-based design">Platform-based</a></li> <li><a href="/wiki/Policy-based_design" class="mw-redirect" title="Policy-based design">Policy-based</a></li> <li><a href="/wiki/Process-centered_design" title="Process-centered design">Process-centered</a></li> <li><a href="/wiki/Public_interest_design" title="Public interest design">Public interest</a></li> <li><a class="mw-selflink selflink">Rational</a></li> <li><a href="/wiki/Regenerative_design" title="Regenerative design">Regenerative</a></li> <li><a href="/wiki/Reliability_engineering" title="Reliability engineering">Reliability engineering</a></li> <li><a href="/wiki/Research-based_design" title="Research-based design">Research-based</a></li> <li><a href="/wiki/Responsibility-driven_design" title="Responsibility-driven design">Responsibility-driven</a></li> <li><a href="/wiki/Responsive_web_design" title="Responsive web design">RWD</a></li> <li><a href="/wiki/Safe-life_design" title="Safe-life design">Safe-life</a></li> <li><a href="/wiki/Sustainable_design" title="Sustainable design">Sustainable</a></li> <li><a href="/wiki/Systemic_design" title="Systemic design">Systemic</a> <ul><li><a href="/wiki/Systems-oriented_design" title="Systems-oriented design">SOD</a></li></ul></li> <li><a href="/wiki/Tableless_web_design" title="Tableless web design">Tableless web</a></li> <li><a href="/wiki/Theory_of_constraints" title="Theory of constraints">Theory of constraints</a></li> <li><a href="/wiki/Top-down_and_bottom-up_design" class="mw-redirect" title="Top-down and bottom-up design">Top-down and bottom-up</a></li> <li><a href="/wiki/Transformation_design" title="Transformation design">Transformation</a></li> <li><a href="/wiki/Transgenerational_design" title="Transgenerational design">Transgenerational</a></li> <li><a href="/wiki/TRIZ" title="TRIZ">TRIZ</a></li> <li><a href="/wiki/Universal_design" title="Universal design">Universal</a> <ul><li><a href="/wiki/Design_for_All_(in_ICT)" title="Design for All (in ICT)">Design for All</a></li></ul></li> <li><a href="/wiki/Usage-centered_design" title="Usage-centered design">Usage-centered</a></li> <li><a href="/wiki/Use-centered_design" title="Use-centered design">Use-centered</a></li> <li><a href="/wiki/User-centered_design" title="User-centered design">User-centered</a> <ul><li><a href="/wiki/Empathic_design" title="Empathic design">Empathic</a></li></ul></li> <li><a href="/wiki/User_innovation" title="User innovation">User innovation</a></li> <li><a href="/wiki/Value-driven_design" title="Value-driven design">Value-driven</a></li> <li><a href="/wiki/Value_sensitive_design" title="Value sensitive design">Value sensitive</a> <ul><li><a href="/wiki/Privacy_by_design" title="Privacy by design">Privacy by</a></li></ul></li></ul> <ul><li>Design <a href="/wiki/Design_choice" title="Design choice">choice</a></li> <li><a href="/wiki/Design_computing" title="Design computing">computing</a></li> <li><a href="/wiki/Design_controls" title="Design controls">controls</a></li> <li><a href="/wiki/Design_culture" title="Design culture">culture</a></li> <li><a href="/wiki/Design_flow_(EDA)" title="Design flow (EDA)">flow</a></li> <li><a href="/wiki/Design_leadership" title="Design leadership">leadership</a></li> <li><a href="/wiki/Design_management" title="Design management">management</a></li> <li><a href="/wiki/Design_marker" title="Design marker">marker</a></li> <li><a href="/wiki/Design_methods" title="Design methods">methods</a></li> <li><a href="/wiki/Design_pattern" title="Design pattern">pattern</a></li> <li><a href="/wiki/Design_research" title="Design research">research</a></li> <li><a href="/wiki/Design_science" title="Design science">science</a></li> <li><a href="/wiki/Design_sprint" title="Design sprint">sprint</a></li> <li><a href="/wiki/Design_strategy" class="mw-redirect" title="Design strategy">strategy</a></li> <li><a href="/wiki/Design_theory" title="Design theory">theory</a></li> <li><a href="/wiki/Design_thinking" title="Design thinking">thinking</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><div id="ToolsIntellectual_propertyOrganizationsAwards" style="font-size:114%;margin:0 4em"><div class="hlist"><ul><li>Tools</li><li>Intellectual property</li><li>Organizations</li><li>Awards</li></ul></div></div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Design_tool" title="Design tool">Tools</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Algorithms-Aided_Design" title="Algorithms-Aided Design">AAD</a></li> <li><a href="/wiki/Architectural_model" title="Architectural model">Architectural model</a></li> <li><a href="/wiki/Blueprint" title="Blueprint">Blueprint</a></li> <li><a href="/wiki/Comprehensive_layout" title="Comprehensive layout">Comprehensive layout</a></li> <li><a href="/wiki/Computer-aided_design" title="Computer-aided design">CAD</a> <ul><li><a href="/wiki/Computer-aided_industrial_design" title="Computer-aided industrial design">CAID</a></li> <li><a href="/wiki/Virtual_home_design_software" title="Virtual home design software">Virtual home design software</a></li></ul></li> <li><a href="/wiki/Computer-automated_design" title="Computer-automated design">CAutoD</a></li> <li><a href="/wiki/Design_quality_indicator" title="Design quality indicator">Design quality indicator</a></li> <li><a href="/wiki/Electronic_design_automation" title="Electronic design automation">Electronic design automation</a></li> <li><a href="/wiki/Flowchart" title="Flowchart">Flowchart</a></li> <li><a href="/wiki/Mockup" title="Mockup">Mockup</a></li> <li><a href="/wiki/Design_specification" title="Design specification">Design specification</a></li> <li><a href="/wiki/Prototype" title="Prototype">Prototype</a></li> <li><a href="/wiki/Sketch_(drawing)" title="Sketch (drawing)">Sketch</a></li> <li><a href="/wiki/Storyboard" title="Storyboard">Storyboard</a></li> <li><a href="/wiki/Technical_drawing" title="Technical drawing">Technical drawing</a></li> <li><a href="/wiki/HTML_editor" title="HTML editor">HTML editor</a></li> <li><a href="/wiki/Website_wireframe" title="Website wireframe">Website wireframe</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Intellectual<br />property</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Community_design" title="Community design">Community design</a></li> <li><a href="/wiki/Design_around" title="Design around">Design around</a></li> <li><a href="/wiki/Design_infringement" title="Design infringement">Design infringement</a></li> <li><a href="/wiki/Design_patent" title="Design patent">Design patent</a></li> <li><a href="/wiki/Fashion_design_copyright" title="Fashion design copyright">Fashion design copyright</a></li> <li><i><a href="/wiki/Geschmacksmuster" title="Geschmacksmuster">Geschmacksmuster</a></i></li> <li><a href="/wiki/Industrial_design_right" title="Industrial design right">Industrial design rights</a> <ul><li><a href="/wiki/Industrial_design_rights_in_the_European_Union" title="Industrial design rights in the European Union">European Union</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Organizations</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/American_Institute_of_Graphic_Arts" title="American Institute of Graphic Arts">American Institute of Graphic Arts</a></li> <li><a href="/wiki/Chartered_Society_of_Designers" title="Chartered Society of Designers">Chartered Society of Designers</a></li> <li><a href="/wiki/Design_and_Industries_Association" title="Design and Industries Association">Design and Industries Association</a></li> <li><a href="/wiki/Design_Council" title="Design Council">Design Council</a></li> <li><a href="/wiki/International_Forum_Design" title="International Forum Design">International Forum Design</a></li> <li><a href="/wiki/Design_Research_Society" title="Design Research Society">Design Research Society</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Awards</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/European_Design_Award" class="mw-redirect" title="European Design Award">European Design Award</a></li> <li><a href="/wiki/German_Design_Award" title="German Design Award">German Design Award</a></li> <li><a href="/wiki/Good_Design_Award_(Museum_of_Modern_Art)" title="Good Design Award (Museum of Modern Art)">Good Design Award (Museum of Modern Art)</a></li> <li><a href="/wiki/Good_Design_Award_(Chicago_Athenaeum)" class="mw-redirect" title="Good Design Award (Chicago Athenaeum)">Good Design Award (Chicago Athenaeum)</a></li> <li><a href="/wiki/Graphex" class="mw-redirect" title="Graphex">Graphex</a></li> <li><a href="/wiki/IF_Product_Design_Award" title="IF Product Design Award">IF Product Design Award</a></li> <li><a href="/wiki/James_Dyson_Award" title="James Dyson Award">James Dyson Award</a></li> <li><a href="/wiki/Prince_Philip_Designers_Prize" title="Prince Philip Designers Prize">Prince Philip Designers Prize</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><div id="Related_topics" style="font-size:114%;margin:0 4em">Related topics</div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Agile_software_development" title="Agile software development">Agile</a></li> <li><a href="/wiki/Concept_art" title="Concept art">Concept art</a></li> <li><a href="/wiki/Conceptual_design" title="Conceptual design">Conceptual design</a></li> <li><a href="/wiki/Creative_industries" title="Creative industries">Creative industries</a></li> <li><a href="/wiki/Cultural_icon" title="Cultural icon">Cultural icon</a></li> <li><a href="/wiki/.design" title=".design">.design</a></li> <li><a href="/wiki/Enterprise_architecture" title="Enterprise architecture">Enterprise architecture</a></li> <li><a href="/wiki/Form_factor_(design)" title="Form factor (design)">Form factor</a></li> <li><a href="/wiki/Futures_studies" title="Futures studies">Futures studies</a></li> <li><a href="/wiki/Indie_design" title="Indie design">Indie design</a></li> <li><a href="/wiki/Innovation_management" title="Innovation management">Innovation management</a></li> <li><a href="/wiki/Intelligent_design" title="Intelligent design">Intelligent design</a></li> <li><a href="/wiki/Lean_startup" title="Lean startup">Lean startup</a></li> <li><a href="/wiki/New_product_development" title="New product development">New product development</a></li> <li><a href="/wiki/OODA_loop" title="OODA loop">OODA loop</a></li> <li><a href="/wiki/Philosophy_of_design" title="Philosophy of design">Philosophy of design</a></li> <li><a href="/wiki/Process_simulation" title="Process simulation">Process simulation</a></li> <li><a href="/wiki/Slow_design" class="mw-redirect" title="Slow design">Slow design</a></li> <li><a href="/wiki/STEAM_fields" class="mw-redirect" title="STEAM fields">STEAM fields</a></li> <li><a href="/wiki/Argument_from_poor_design" title="Argument from poor design">Unintelligent design</a></li> <li><a href="/wiki/Visualization_(graphics)" title="Visualization (graphics)">Visualization</a></li> <li><a href="/wiki/Wicked_problem" title="Wicked problem">Wicked problem</a></li></ul> <ul><li>Design <a href="/wiki/Design_brief" title="Design brief">brief</a></li> <li><a href="/wiki/Design_change" title="Design change">change</a></li> <li><a href="/wiki/Design_classic" title="Design classic">classic</a></li> <li><a href="/wiki/Design_competition" title="Design competition">competition</a> <ul><li><a href="/wiki/Architectural_design_competition" title="Architectural design competition">architectural</a></li> <li><a href="/wiki/Student_design_competition" title="Student design competition">student</a></li></ul></li> <li><a href="/wiki/Design_director" title="Design director">director</a></li> <li><a href="/wiki/Design_education" title="Design education">education</a></li> <li><a href="/wiki/Design_elements" title="Design elements">elements</a></li> <li><a href="/wiki/Design_engineer" title="Design engineer">engineer</a></li> <li><a href="/wiki/Design_firm" class="mw-redirect" title="Design firm">firm</a></li> <li><a href="/wiki/Design_history" title="Design history">history</a></li> <li><a href="/wiki/Design_knowledge" title="Design knowledge">knowledge</a></li> <li><a href="/wiki/Design_language" title="Design language">language</a></li> <li><a href="/wiki/Design_life" title="Design life">life</a></li> <li><a href="/wiki/Design_load" title="Design load">load</a></li> <li><a href="/wiki/Design_museum" title="Design museum">museum</a></li> <li><a href="/wiki/Design_paradigm" title="Design paradigm">paradigm</a></li> <li><a href="/wiki/Design_principles" title="Design principles">principles</a></li> <li><a href="/wiki/Design_rationale" title="Design rationale">rationale</a></li> <li><a href="/wiki/Design_review" title="Design review">review</a></li> <li><a href="/wiki/Design_specification" title="Design specification">specification</a></li> <li><a href="/wiki/Design_studies" title="Design studies">studies</a></li> <li><a href="/wiki/Design_studio" class="mw-redirect" title="Design studio">studio</a></li> <li><a href="/wiki/Design_technology" title="Design technology">technology</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><td class="navbox-abovebelow" colspan="2"><div> <ul><li><a href="https://commons.wikimedia.org/wiki/category:Design" class="extiw" title="commons:category:Design"> <span class="tmp-color" style="color:#002bb8">Commons</span> </a></li> <li><a href="https://en.wikibooks.org/wiki/Design" class="extiw" title="wikibooks:Design"> <span class="tmp-color" style="color:#002bb8">Wikibooks</span> </a></li> <li><a href="https://en.wikinews.org/wiki/Special:Search/Design" class="extiw" title="wikinews:Special:Search/Design"> <span class="tmp-color" style="color:#002bb8">Wikinews</span> </a></li> <li><a href="https://en.wikiquote.org/wiki/Design" class="extiw" title="wikiquote:Design"> <span class="tmp-color" style="color:#002bb8">Wikiquote</span> </a></li> <li><a href="https://en.wikisource.org/wiki/Category:Design" class="extiw" title="wikisource:Category:Design"> <span class="tmp-color" style="color:#002bb8">Wikisource</span> </a></li> <li><a href="https://en.wiktionary.org/wiki/Design" class="extiw" title="wiktionary:Design"> <span class="tmp-color" style="color:#002bb8">Wiktionary</span> </a></li></ul> </div></td></tr></tbody></table></div> <p><br /> </p> <style data-mw-deduplicate="TemplateStyles:r1012311289">.mw-parser-output .asbox{position:relative;overflow:hidden}.mw-parser-output .asbox table{background:transparent}.mw-parser-output .asbox p{margin:0}.mw-parser-output .asbox p+p{margin-top:0.25em}.mw-parser-output .asbox-body{font-style:italic}.mw-parser-output .asbox-note{font-size:smaller}.mw-parser-output .asbox .navbar{position:absolute;top:-0.75em;right:1em;display:none}</style><div role="note" class="metadata plainlinks asbox stub"><table role="presentation"><tbody><tr class="noresize"><td><span typeof="mw:File"><a href="/wiki/File:Rotaxane.png" class="mw-file-description"><img alt="Stub icon" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/85/Rotaxane.png/38px-Rotaxane.png" decoding="async" width="38" height="25" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/85/Rotaxane.png/57px-Rotaxane.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/85/Rotaxane.png/76px-Rotaxane.png 2x" data-file-width="361" data-file-height="242" /></a></span></td><td><p class="asbox-body">This nanotechnology-related article is a <a href="/wiki/Wikipedia:Stub" title="Wikipedia:Stub">stub</a>. 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