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Search results for: N. Slavov

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Slavov</title> <meta name="description" content="Search results for: N. Slavov"> <meta name="keywords" content="N. Slavov"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none navbar-toggler ml-auto" type="button" data-toggle="collapse" data-target="#navbarMenu" aria-controls="navbarMenu" aria-expanded="false" aria-label="Toggle navigation"> <span class="navbar-toggler-icon"></span> </button> <div class="w-100"> <div class="d-none d-lg-flex flex-row-reverse"> <form method="get" action="https://waset.org/search" class="form-inline my-2 my-lg-0"> <input class="form-control mr-sm-2" type="search" placeholder="Search Conferences" value="N. 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Slavov"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 2</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: N. Slavov</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Carriage of 675 4G/5G Polymorphism in PAI-1 Gene and Its Association with Early Pregnancy Losses in Patients with Polycystic Ovary Syndrome</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=R.%20Komsa-Penkova">R. Komsa-Penkova</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20Golemanov"> G. Golemanov</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20Georgieva"> G. Georgieva</a>, <a href="https://publications.waset.org/abstracts/search?q=K.%20Popovski"> K. Popovski</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Slavov"> N. Slavov</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20Ivanov"> P. Ivanov</a>, <a href="https://publications.waset.org/abstracts/search?q=K.%20Kovacheva"> K. Kovacheva</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Rathee"> S. Rathee</a>, <a href="https://publications.waset.org/abstracts/search?q=E.%20Konova"> E. Konova</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Blajev"> A. Blajev</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Leptin and PAI-1 are important cytokines and may play a role in the regulation of PCOS development. PCOS is frequently associated with obesity, high BMI index and consequently with increased risk of metabolic disorders. The aim of the present study was to evaluate PAI-1 levels, genetic influence of the carriage of 675 4G/5G polymorphism in PAI-1 gene and leptin as a marker of obesity in the development of PCOS. Methods: Genotyping in 84 patients with PCOS and PCO and 100 healthy control subjects to detect single nucleotide deletion 675 G in the promoter of PAI-1 gene. The present study provides evidence that SNP 4G in the PAI-1 gene is associated with early pregnancy losses in patients with polycystosis. Further to this, there is a correlation between leptin levels, PAI-1 levels and BMI in the patients with PCOS, which confirms the role of obesity as a risk factor for PCOS. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=carriage%20of%20675%204G%2F5G%20polymorphism" title="carriage of 675 4G/5G polymorphism">carriage of 675 4G/5G polymorphism</a>, <a href="https://publications.waset.org/abstracts/search?q=PCOS" title=" PCOS"> PCOS</a>, <a href="https://publications.waset.org/abstracts/search?q=early%20pregnancy%20losses" title=" early pregnancy losses"> early pregnancy losses</a>, <a href="https://publications.waset.org/abstracts/search?q=PAI-1%20gene" title=" PAI-1 gene"> PAI-1 gene</a> </p> <a href="https://publications.waset.org/abstracts/13903/carriage-of-675-4g5g-polymorphism-in-pai-1-gene-and-its-association-with-early-pregnancy-losses-in-patients-with-polycystic-ovary-syndrome" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/13903.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">331</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Changes in Serum Neopterin in Workers Exposed to Different Mineral Dust</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Gospodinka%20Prakova">Gospodinka Prakova</a>, <a href="https://publications.waset.org/abstracts/search?q=Pavlina%20Gidikova"> Pavlina Gidikova</a>, <a href="https://publications.waset.org/abstracts/search?q=Gergana%20Sandeva"> Gergana Sandeva</a>, <a href="https://publications.waset.org/abstracts/search?q=Kamelia%20Haracherova"> Kamelia Haracherova</a>, <a href="https://publications.waset.org/abstracts/search?q=Emil%20Slavov"> Emil Slavov</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Neopterin was demonstrated to be a sensitive marker of cell-mediated immune reactions which plays a key role in the interaction of monocyte / macrophage activation. The purpose of this work was to investigate changes in serum neopterin in workers exposed to different composition of mineral dust. Material and Methods: Serum neopterin was studied in 193 exposed workers, divided into three groups, depending on the mineral dust and content of the quartz in the respirable fraction. The I-st group-coal dust containing less than 2% free crystalline silica (n=44), II-nd group-coal dust containing over 2% free crystalline silica (n=94) and the III-rd group-mixed dust with corundum and carborundum (n=55). The control group was composed of 21 individuals without exposure to dust. Serum neopterin was investigated by Elisa method in ng/ml according to the instructions of the manufacturer. Results and Discussion: It was found significantly higher level of serum neopterin in exposed workers of mineral dust (2,10 卤 0,62 ng / ml), compared with that of the control group (1,10 卤 0,85 ng/ml; p < 0,05). Neopterin levels in workers exposed to coal dust (1,87 卤 0,42 ng / ml-I-st and 3,32 卤 0,77 ng / ml-II-nd group) were significantly higher compared with those exposed to a mixed dust (1,31卤0,68 mg / ml-third) and control group (p < 0,05). No significant difference in serum neopterin when exposed to a mixed dust composed of corundum and carborundum (III-rd) and a control group. Conclusion: The results of this study indicate activates a cell-mediated immune response when exposed to a mineral dust. The level of that activation depends mainly on the composition of the dust and is significantly highest in workers exposed to coal dust. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=mineral%20dust" title="mineral dust">mineral dust</a>, <a href="https://publications.waset.org/abstracts/search?q=neopterin" title=" neopterin"> neopterin</a>, <a href="https://publications.waset.org/abstracts/search?q=occupational%20exposure" title=" occupational exposure"> occupational exposure</a>, <a href="https://publications.waset.org/abstracts/search?q=respirable%20crystalline%20silica" title=" respirable crystalline silica"> respirable crystalline silica</a> </p> <a href="https://publications.waset.org/abstracts/69706/changes-in-serum-neopterin-in-workers-exposed-to-different-mineral-dust" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/69706.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">266</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET celebrates its 16th foundational anniversary</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Account <li><a href="https://waset.org/profile">My Account</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Explore <li><a href="https://waset.org/disciplines">Disciplines</a></li> <li><a href="https://waset.org/conferences">Conferences</a></li> <li><a href="https://waset.org/conference-programs">Conference Program</a></li> <li><a href="https://waset.org/committees">Committees</a></li> <li><a href="https://publications.waset.org">Publications</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Research <li><a href="https://publications.waset.org/abstracts">Abstracts</a></li> <li><a href="https://publications.waset.org">Periodicals</a></li> <li><a href="https://publications.waset.org/archive">Archive</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Open Science <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Philosophy.pdf">Open Science Philosophy</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Award.pdf">Open Science Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Society-Open-Science-and-Open-Innovation.pdf">Open Innovation</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Postdoctoral-Fellowship-Award.pdf">Postdoctoral Fellowship Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Scholarly-Research-Review.pdf">Scholarly Research Review</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Support <li><a href="https://waset.org/page/support">Support</a></li> <li><a href="https://waset.org/profile/messages/create">Contact Us</a></li> <li><a href="https://waset.org/profile/messages/create">Report Abuse</a></li> </ul> </div> </div> </div> </div> </div> <div class="container text-center"> <hr style="margin-top:0;margin-bottom:.3rem;"> <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank" class="text-muted small">Creative Commons Attribution 4.0 International License</a> <div id="copy" class="mt-2">&copy; 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