Turku Bioscience – Turku Bioscience Centre formerly Turku Centre for Biotechnology

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class="g-owlcarousel-item-content"> <h1 class="g-owlcarousel-item-title">Biological and biomedical research </h1> <div class="g-owlcarousel-item-link"> <a target="_self" class="g-owlcarousel-item-button button button-outline" href="https://bioscience.fi/research/"> Groups </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </header> <section id="g-above"> <div class="g-container"> <div class="g-grid"> <div class="g-block size-100 mobile-menu-target"> <div id="menu-5534-particle" class="g-content g-particle"> <div class="alert alert-error">No menu selected</div> </div> </div> </div> </div> </section> <section id="g-container-main" class="g-wrapper"> <div class="g-container"> <div class="g-grid"> <div class="g-block size-25"> <aside id="g-aside"> <div class="g-grid"> <div class="g-block size-100"> <div id="custom-4554-particle" class="g-content g-particle"> <h3 id="recent-publications-header">Recent publications</h3> <div class="publications"> </div> </div> </div> <div class="g-grid"> <div id="publication-column" class="g-block size-100"> <div id="custom-9500-particle" class="g-content g-particle"> Nissi L. et al. xCT as a Predictor for Survival in a Population-Based Cohort of Head and Neck Squamous Cell Carcinoma. Cancer Medicine. 2024. Nov;13(21):e70371. <a href="https://pubmed.ncbi.nlm.nih.gov/39487701/" target="new"><b>Pubmed→</b></a> <hr> Punovuori K et al. Multiparameter imaging reveals clinically relevant cancer cell-stroma interaction dynamics in head and neck cancer. Cell. 2024. Oct 22:S0092-8674(24)01146-2. <a href="https://pubmed.ncbi.nlm.nih.gov/39471809/" target="new"><b>Link→</b></a> <hr> Steffen CL et al. Identification of an H-Ras nanocluster disrupting peptide. Communications Biology. 7, 837 (2024).<a href="https://www.nature.com/articles/s42003-024-06523-9" target="new"><b>Link→</b></a> <hr> Armenteros JJA et al. Multi-omics analysis reveals drivers of loss of β-cell function after newly diagnosed autoimmune type 1 diabetes: An INNODIA multicenter study. Diabetes/Metabolism Research and Reviews. 2024: 40:e3833. <a href="https://onlinelibrary.wiley.com/doi/10.1002/dmrr.3833" target="new"><b>Link→</b></a> <hr> Momeny M et al. DUSP6 inhibition overcomes neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer. EMBO Molecular Medicine. 2024 June 17. <a href="https://www.embopress.org/doi/full/10.1038/s44321-024-00088-0" target="new"><b>Link→</b></a> <hr> Starskaia I. Distinct cellular immune responses in children en route to type 1 diabetes with different first-appearing autoantibodies. Nature Communications. 2024 May 7;15(1):3810. <a href="https://pubmed.ncbi.nlm.nih.gov/38714671/" target="new"><b>Pubmed→</b></a> <hr> Kalim UU et al. A proximal enhancer regulates RORA expression during early human Th17 cell differentiation. Journal of Clinical Immunology. 2024 May 22:264:110261.<a href="https://pubmed.ncbi.nlm.nih.gov/38788884/" target="new"><b>Pubmed→</b></a> <hr> Andrabi SBA et al. Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4+ regulatory T cells by regulating IL2RA. Proceedings of the National Academy of Sciences of the United States of America. 2024 Jun 4;121(23). <a href="https://pubmed.ncbi.nlm.nih.gov/38805281/" target="new"><b>Pubmed→</b></a> <hr> Bhattacharya D & al. Single-cell characterisation of tissue homing CD4 + and CD8 + T cell clones in immune-mediated refractory arthritis. Molecular Medicine. 2024, 30, 48. <a href="https://rdcu.be/dEjQk" target="new"><b>Link →</b></a> <hr> Koskinen LM & al. Spatial Engineering of Mammary Epithelial Cell Cultures with 3D Bioprinting Reveals Growth Control by Branch Point Proximity. Journal of Mammary Gland Biology and Neoplasia. 2024 Feb 28;29(1):5.<a href="https://pubmed.ncbi.nlm.nih.gov/38416267/" target="new"><b>Link →</b></a> <hr> Buchacher T & al. PIM kinases regulate early human Th17 cell differentiation. Cell Reports. 2023 Dec 26;42(12):113469.<a href="https://pubmed.ncbi.nlm.nih.gov/38039135/" target="new"><b>Link →</b></a> <hr> Andrabi et al. HIC1 interacts with FOXP3 multi protein complex: Novel pleiotropic mechanisms to regulate human regulatory T cell differentiation and function. Immunology Letters. 2023 Nov:263:123-132. <a href="https://pubmed.ncbi.nlm.nih.gov/37838026/" target="new"><b>Link →</b></a> <hr> M K Hirvonen et al. Serum APOC1 levels are decreased in young autoantibody positive children who rapidly progress to type 1 diabetes. Scientific Reports. 2023 Sep 24;13(1):15941. <a href="https://pubmed.ncbi.nlm.nih.gov/37743383/" target="new"><b>Link →</b></a> <hr> Nagelli S et al. CIP2A coordinates phosphosignaling, mitosis, and the DNA damage response. Trends in Cancer. 2023 Oct 2. <a href="https://www.sciencedirect.com/science/article/pii/S2405803323001735#bi0005/" target="new"><b>Link →</b></a> <hr> Oras A et al. Profiling of peripheral blood B-cell transcriptome in children who developed coeliac disease in a prospective study. Heliyon. 2023 Jan 21;9(2):e13147. <a href="https://pubmed.ncbi.nlm.nih.gov/36718152/" target="new"><b>Pubmed →</b></a> <hr> Brunell A E et al. Exhausted T cells hijacking the cancer-immunity cycle: Assets and liabilities. Frontiers in Immunology. 2023 Apr 14;14:1151632.<a href="https://pubmed.ncbi.nlm.nih.gov/37122741/" target="new"><b>Pubmed →</b></a> <hr> Suomi T et al. Gene expression signature predicts rate of type 1 diabetes progression. EBioMedicine. 2023 Jun;92:104625. <a href="https://pubmed.ncbi.nlm.nih.gov/37224769/" target="new"><b>Pubmed →</b></a> <hr> Moulder R et al. Targeted serum proteomics of longitudinal samples from newly diagnosed youth with type 1 diabetes distinguishes markers of disease and C-peptide trajectory. Diabetologia. 2023 Nov;66(11):1983-1996. <a href="https://pubmed.ncbi.nlm.nih.gov/37537394/" target="new"><b>Pubmed →</b></a> <hr> Lamichhane S et al. Circulating metabolic signatures of rapid and slow progression to type 1 diabetes in islet autoantibody-positive children. Frontiers in Endocrinology. 2023 Sep 6;14:1211015. <a href="https://pubmed.ncbi.nlm.nih.gov/37745723/" target="new"><b>Pubmed →</b></a> <hr> Hirvonen M K et al. Serum APOC1 levels are decreased in young autoantibody positive children who rapidly progress to type 1 diabetes. Scientific Reports. 2023 Sep 24;13(1):15941. <a href="https://pubmed.ncbi.nlm.nih.gov/37743383/" target="new"><b>Pubmed →</b></a> <hr> Cazzoli R et al. Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition. Cell Reports. 2023 Jun 7;42(6):112616. Online ahead of print. <a href="https://pubmed.ncbi.nlm.nih.gov/37289585/" target="new"><b>Pubmed →</b></a> <hr> Örd T et al. Dissecting the polygenic basis of atherosclerosis via disease-associated cell state signatures. American Journal of Human Genetics. 2023.Apr 11;S0002-9297(23)00097-6. <a href="https://pubmed.ncbi.nlm.nih.gov/37060905/" target="new"><b>Pubmed →</b></a> <hr> Westermarck J. Inhibition of adaptive therapy tolerance in cancer: is triplet mitochondrial targeting the key?. Molecular Oncology. 2023. Feb 28. <a href="https://pubmed.ncbi.nlm.nih.gov/36852624/" target="new"><b>Pubmed →</b></a> <hr> Huuhtanen J. et al. Single-cell characterization of anti-LAG3+anti-PD1 treatment in melanoma patients. Journal of Clinical Investigation. 2023. Jan 31;e164809. <a href="https://pubmed.ncbi.nlm.nih.gov/36719749/" target="new"><b>Pubmed →</b></a> <hr> Aakula A et al. RAS and PP2A activities converge on epigenetic gene regulation. Life Science Alliance. 2023 Mar 1;6(5):e202301928. <a href="https://pubmed.ncbi.nlm.nih.gov/36858798/" target="new"><b>Pubmed →</b></a> <hr> Pavic K et al. Structural mechanism for inhibition of PP2A-B56α and oncogenicity by CIP2A. 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class="eventless em-cal-day em-cal-col-3"> <div class="em-cal-day-date"> <span>9</span> </div> </div> <div class="eventless em-cal-day em-cal-col-4"> <div class="em-cal-day-date"> <span>10</span> </div> </div> <div class="eventless-today em-cal-day em-cal-col-5"> <div class="em-cal-day-date"> <span>11</span> </div> </div> <div class="eventless em-cal-day em-cal-col-6"> <div class="em-cal-day-date"> <span>12</span> </div> </div> <div class="eventless em-cal-day em-cal-col-7"> <div class="em-cal-day-date"> <span>13</span> </div> </div> <div class="eventless em-cal-day em-cal-col-1"> <div class="em-cal-day-date"> <span>14</span> </div> </div> <div class="eventless em-cal-day em-cal-col-2"> <div class="em-cal-day-date"> <span>15</span> </div> </div> <div class="eventless em-cal-day em-cal-col-3"> <div class="em-cal-day-date"> <span>16</span> </div> </div> <div class="eventless em-cal-day em-cal-col-4"> <div class="em-cal-day-date"> <span>17</span> </div> </div> <div class="eventless em-cal-day em-cal-col-5"> <div class="em-cal-day-date"> <span>18</span> </div> </div> <div class="eventless em-cal-day em-cal-col-6"> <div class="em-cal-day-date"> <span>19</span> </div> </div> <div class="eventless em-cal-day em-cal-col-7"> <div class="em-cal-day-date"> <span>20</span> </div> </div> <div class="eventless em-cal-day em-cal-col-1"> <div class="em-cal-day-date"> <span>21</span> </div> </div> <div class="eventless em-cal-day em-cal-col-2"> <div class="em-cal-day-date"> <span>22</span> </div> </div> <div class="eventless em-cal-day em-cal-col-3"> <div class="em-cal-day-date"> <span>23</span> </div> </div> <div class="eventless em-cal-day em-cal-col-4"> <div class="em-cal-day-date"> <span>24</span> </div> </div> <div class="eventless em-cal-day em-cal-col-5"> <div class="em-cal-day-date"> <span>25</span> </div> </div> <div class="eventless em-cal-day em-cal-col-6"> <div class="em-cal-day-date"> <span>26</span> </div> </div> <div class="eventless em-cal-day em-cal-col-7"> <div class="em-cal-day-date"> <span>27</span> </div> </div> <div class="eventless em-cal-day em-cal-col-1"> <div class="em-cal-day-date"> <span>28</span> </div> </div> <div class="eventless em-cal-day em-cal-col-2"> <div class="em-cal-day-date"> <span>29</span> </div> </div> <div class="eventless em-cal-day em-cal-col-3"> <div class="em-cal-day-date"> <span>30</span> </div> </div> <div class="eventless-post em-cal-day em-cal-col-4"> <div class="em-cal-day-date"> <span>1</span> </div> </div> <div class="eventless-post em-cal-day em-cal-col-5"> <div class="em-cal-day-date"> <span>2</span> </div> </div> <div class="eventless-post em-cal-day em-cal-col-6"> <div class="em-cal-day-date"> <span>3</span> </div> </div> <div class="eventless-post em-cal-day em-cal-col-7"> <div class="em-cal-day-date"> <span>4</span> </div> </div> </section><section class="em-cal-events-content" id="em-cal-events-content-686147516"> <div class="em pixelbones em-calendar-preview em-modal em-cal-event-content" data-event-id="938" data-parent="em-cal-events-content-686147516"> <div class="em-modal-popup"> <header> <a class="em-close-modal"></a> <div class="em-modal-title"> <a href="https://bioscience.fi/events/guest-seminar-maheswara-reddy-emani/">Cancelled: MIST Guest Seminar: Maheswara Reddy Emani</a> </div> </header> <div class="em-modal-content"> <div class="em pixelbones em-calendar-preview em-list em-events-list"> <div class="em-event em-item" style="--default-border:#a8d144;"> <div class="em-item-image "> <img src='https://bioscience.fi/wp-content/uploads/2025/03/Mahesh-photo.png' alt='Cancelled: MIST Guest Seminar: Maheswara Reddy Emani'/> </div> <div class="em-item-info"> <div class="em-event-meta em-item-meta"> <div class="em-item-meta-line em-event-date em-event-meta-datetime"> <span class="em-icon-calendar em-icon"></span> 31.3.2025 </div> <div class="em-item-meta-line em-event-time em-event-meta-datetime"> <span class="em-icon-clock em-icon"></span> 15:00 - 16:00 </div> <div class="em-item-meta-line em-item-taxonomy em-event-categories"> <span class="em-icon-category em-icon"></span> <div> <ul class="event-categories"> <li><a href="https://bioscience.fi/events/categories/frontpage-events/">Events</a></li> </ul> </div> </div> </div> <div class="em-item-desc"> </div> <div class="em-item-actions input"> <a class="em-item-read-more button" href="https://bioscience.fi/events/guest-seminar-maheswara-reddy-emani/">More Info</a> </div> </div> </div> </div> </div> </div> </div> <div class="em pixelbones em-calendar-preview em-modal em-cal-event-content" data-event-id="933" data-parent="em-cal-events-content-686147516"> <div class="em-modal-popup"> <header> <a class="em-close-modal"></a> <div class="em-modal-title"> <a href="https://bioscience.fi/events/immunology-seminar-series-osamu-takeuchi/">Immunology Seminar Series: Osamu Takeuchi</a> </div> </header> <div class="em-modal-content"> <div class="em pixelbones em-calendar-preview em-list em-events-list"> <div class="em-event em-item" style="--default-border:#a8d144;"> <div class="em-item-image "> <img src='https://bioscience.fi/wp-content/uploads/2025/02/Thumbnail-web-01042025.png' alt='Immunology Seminar Series: Osamu Takeuchi'/> </div> <div class="em-item-info"> <div class="em-event-meta em-item-meta"> <div class="em-item-meta-line em-event-date em-event-meta-datetime"> <span class="em-icon-calendar em-icon"></span> 1.4.2025 </div> <div class="em-item-meta-line em-event-time em-event-meta-datetime"> <span class="em-icon-clock em-icon"></span> 14:00 - 15:00 </div> <div class="em-item-meta-line em-item-taxonomy em-event-categories"> <span class="em-icon-category em-icon"></span> <div> <ul class="event-categories"> <li><a href="https://bioscience.fi/events/categories/frontpage-events/">Events</a></li> </ul> </div> </div> </div> <div class="em-item-desc"> </div> <div class="em-item-actions input"> <a class="em-item-read-more button" href="https://bioscience.fi/events/immunology-seminar-series-osamu-takeuchi/">More Info</a> </div> </div> </div> </div> </div> </div> </div> <div class="em pixelbones em-calendar-preview em-modal em-cal-event-content" data-event-id="925" data-parent="em-cal-events-content-686147516"> <div class="em-modal-popup"> <header> <a class="em-close-modal"></a> <div class="em-modal-title"> <a href="https://bioscience.fi/events/frontiers-of-science-prof-sampsa-hautaniemi/">Frontiers of Science: Prof. Sampsa Hautaniemi</a> </div> </header> <div class="em-modal-content"> <div class="em pixelbones em-calendar-preview em-list em-events-list"> <div class="em-event em-item" style="--default-border:#a8d144;"> <div class="em-item-image "> <img src='https://bioscience.fi/wp-content/uploads/2025/01/hautaniemi400px.jpg' alt='Frontiers of Science: Prof. Sampsa Hautaniemi'/> </div> <div class="em-item-info"> <div class="em-event-meta em-item-meta"> <div class="em-item-meta-line em-event-date em-event-meta-datetime"> <span class="em-icon-calendar em-icon"></span> 3.4.2025 </div> <div class="em-item-meta-line em-event-time em-event-meta-datetime"> <span class="em-icon-clock em-icon"></span> 12:00 - 13:00 </div> <div class="em-item-meta-line em-item-taxonomy em-event-categories"> <span class="em-icon-category em-icon"></span> <div> <ul class="event-categories"> <li><a href="https://bioscience.fi/events/categories/frontpage-events/">Events</a></li> </ul> </div> </div> </div> <div class="em-item-desc"> </div> <div class="em-item-actions input"> <a class="em-item-read-more button" href="https://bioscience.fi/events/frontiers-of-science-prof-sampsa-hautaniemi/">More Info</a> </div> </div> </div> </div> </div> </div> </div> <div class="em pixelbones em-calendar-preview em-modal em-cal-date-content" data-calendar-date="1743379200" data-parent="em-cal-events-content-686147516"> <div class="em-modal-popup"> <header> <a class="em-close-modal"></a> <div class="em-modal-title"> Events on 31.3.2025 </div> </header> <div class="em-modal-content em pixelbones em-calendar-preview em-list-widget em-events-widget"> <div class="em-item em-event" style="--default-border:#a8d144;"> <div class="em-item-image " style="max-width:150px"> <img width="150" height="150" src="https://bioscience.fi/wp-content/uploads/2025/03/Mahesh-photo-150x150.png" class="attachment-150x150 size-150x150 wp-post-image" alt="Cancelled: MIST Guest Seminar: Maheswara Reddy Emani" decoding="async" /> </div> <div class="em-item-info"> <div class="em-item-name"><a href="https://bioscience.fi/events/guest-seminar-maheswara-reddy-emani/">Cancelled: MIST Guest Seminar: Maheswara Reddy Emani</a></div> <div class="em-item-meta"> <div class="em-item-meta-line em-event-date em-event-meta-datetime"> <span class="em-icon em-icon-calendar"></span> <span>31 Mar 25</span> </div> <div class="em-item-meta-line em-event-location em-event-meta-location"> <span class="em-icon em-icon-location"></span> <span>#_TOWN</span> </div> </div> </div> </div> </div> </div> </div> <div class="em pixelbones em-calendar-preview em-modal em-cal-date-content" data-calendar-date="1743465600" data-parent="em-cal-events-content-686147516"> <div class="em-modal-popup"> <header> <a class="em-close-modal"></a> <div class="em-modal-title"> Events on 1.4.2025 </div> </header> <div class="em-modal-content em pixelbones em-calendar-preview em-list-widget em-events-widget"> <div class="em-item em-event" style="--default-border:#a8d144;"> <div class="em-item-image " style="max-width:150px"> <img width="150" height="150" src="https://bioscience.fi/wp-content/uploads/2025/02/Thumbnail-web-01042025-150x150.png" class="attachment-150x150 size-150x150 wp-post-image" alt="Immunology Seminar Series: Osamu Takeuchi" decoding="async" srcset="https://bioscience.fi/wp-content/uploads/2025/02/Thumbnail-web-01042025-150x150.png 150w, https://bioscience.fi/wp-content/uploads/2025/02/Thumbnail-web-01042025-300x300.png 300w, https://bioscience.fi/wp-content/uploads/2025/02/Thumbnail-web-01042025-1024x1024.png 1024w, https://bioscience.fi/wp-content/uploads/2025/02/Thumbnail-web-01042025-768x768.png 768w, https://bioscience.fi/wp-content/uploads/2025/02/Thumbnail-web-01042025.png 1250w" sizes="(max-width: 150px) 100vw, 150px" /> </div> <div class="em-item-info"> <div class="em-item-name"><a href="https://bioscience.fi/events/immunology-seminar-series-osamu-takeuchi/">Immunology Seminar Series: Osamu Takeuchi</a></div> <div class="em-item-meta"> <div class="em-item-meta-line em-event-date em-event-meta-datetime"> <span class="em-icon em-icon-calendar"></span> <span>1 Apr 25</span> </div> <div class="em-item-meta-line em-event-location em-event-meta-location"> <span class="em-icon em-icon-location"></span> <span>#_TOWN</span> </div> </div> </div> </div> </div> </div> </div> <div class="em pixelbones em-calendar-preview em-modal em-cal-date-content" data-calendar-date="1743638400" 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Turku Bioscience – Turku Bioscience Centre formerly Turku Centre for Biotechnology