January 2020 - Cancer Currents Blog

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Researchers are trying to better understand this phenomenon and take advantage of it to improve cancer therapy.</p> <p><a href="/news-events/cancer-currents-blog/2020/cancer-abscopal-effect-radiation-immunotherapy">Continue Reading ></a></p> </div> </div> </li> </li> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2020/melanoma-metastasis-metabolism-mct1"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2020-01/scan-metastatic-melanoma.jpg?h=a307095a&itok=6u9Mtcnf" width="228" height="171" alt="PET/CT scan of a patient with metastatic melanoma." /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2020/melanoma-metastasis-metabolism-mct1" onclick=""> <span>Changes in Metabolism Help Melanomas Spread</span> </a> <div class="description"> <div class="date-author"> <time datetime="2020-01-21T12:00:00Z">January 21, 2020</time>, by NCI Staff </div> <p>Melanoma cells that metastasize to other parts of the body produce high levels of a protein called MCT1, a new study in mice has found. Blocking MCT1 with an investigational drug, AZD3965, led to fewer and smaller metastatic tumors.</p> <p><a href="/news-events/cancer-currents-blog/2020/melanoma-metastasis-metabolism-mct1">Continue Reading ></a></p> </div> </div> </li> </li> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2020/cc-486-aml-improves-survival-maintenance-therapy"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2020-01/DNA-Strand-Graphic_0.jpg?h=870cb720&itok=Shr9L9lS" width="228" height="171" alt="A graphic showing the drug CC-486 interacting with DNA and preventing DNA methylation" /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2020/cc-486-aml-improves-survival-maintenance-therapy" onclick=""> <span>Maintenance Therapy with CC-486 Extends Survival of Adults with AML</span> </a> <div class="description"> <div class="date-author"> <time datetime="2020-01-16T12:00:00Z">January 16, 2020</time>, by NCI Staff </div> <p>Maintenance therapy with CC-486 extended overall survival of adults with the blood cancer acute myeloid leukemia (AML) in a large clinical trial. CC-486 is a pill form of another cancer therapy called azacitidine (Vidaza).</p> <p><a href="/news-events/cancer-currents-blog/2020/cc-486-aml-improves-survival-maintenance-therapy">Continue Reading ></a></p> </div> </div> </li> </li> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2020/enfortumab-vedotin-bladder-cancer-fda-approval"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2020-01/enfortumab-vedotin-%20mechanism-illustration.jpg?h=182730e1&itok=vynXfprv" width="228" height="171" alt="An illustration of enfortumab vedotin's mechanism of action in cancer cells." /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2020/enfortumab-vedotin-bladder-cancer-fda-approval" onclick=""> <span>Enfortumab Vedotin Approved for Recurrent Bladder Cancer</span> </a> <div class="description"> <div class="date-author"> <time datetime="2020-01-14T12:00:00Z">January 14, 2020</time>, by NCI Staff </div> <p>Enfortumab vedotin-ejfv (Padcev) has been approved for people with advanced bladder cancer. FDA granted the drug accelerated approval for cancers that have progressed despite previous treatments.</p> <p><a href="/news-events/cancer-currents-blog/2020/enfortumab-vedotin-bladder-cancer-fda-approval">Continue Reading ></a></p> </div> </div> </li> </li> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2020/tucatinib-trastuzumab-deruxtecan-her2-positive-metastatic-breast-cancer"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2020-01/Fluorescence-in-situ-hybridization.jpg?h=3c898c73&itok=PtXKYTcc" width="228" height="171" alt="An image of breast cancer cells with strong HER2 amplification." /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2020/tucatinib-trastuzumab-deruxtecan-her2-positive-metastatic-breast-cancer" onclick=""> <span>For Metastatic HER2-Positive Breast Cancer, New Treatments Emerge</span> </a> <div class="description"> <div class="date-author"> <time datetime="2020-01-08T12:00:00Z">January 8, 2020</time>, by NCI Staff </div> <p>Tucatinib improved survival for women in the HER2CLIMB trial, including some whose cancer had spread to the brain. Trastuzumab deruxtecan improved survival and shrank many tumors in the DESTINY-Breast01 trial, which led to its accelerated approval.</p> <p><a href="/news-events/cancer-currents-blog/2020/tucatinib-trastuzumab-deruxtecan-her2-positive-metastatic-breast-cancer">Continue Reading ></a></p> </div> </div> </li> </li> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2020/glioblastoma-egfr-dna-circles"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2019-12/ecDNA%20EGFR%20FISH%20unpublished.png?h=778d5ce5&itok=x33iK1Uu" width="228" height="171" alt="A microscopy image showing amplified EGFR in DNA circles that are separate from chromosomes." /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2020/glioblastoma-egfr-dna-circles" onclick=""> <span>Brain Cancer Cells Hijack Gene “On Switches” to Drive Tumor Growth</span> </a> <div class="description"> <div class="date-author"> <time datetime="2020-01-06T12:00:00Z">January 6, 2020</time>, by NCI Staff </div> <p>Glioblastoma cells sneak many copies of a key oncogene into circular pieces of DNA. In a new NCI-funded study, scientists found that the cells also slip several different genetic “on switches” into these DNA circles, helping to fuel the cancer’s growth.</p> <p><a href="/news-events/cancer-currents-blog/2020/glioblastoma-egfr-dna-circles">Continue Reading ></a></p> </div> </div> </li> </li> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2020/new-online-january-2020"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2019-12/prevention-interventions-available-today.jpg?h=c04ac6ad&itok=ESjjBJyw" width="228" height="171" alt="Available cancer prevention interventions include medications, lifestyle choices, treatments for infections, screening tests, protective vaccines, and surgery." /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2020/new-online-january-2020" onclick=""> <span>New on NCI’s Websites for January 2020</span> </a> <div class="description"> <div class="date-author"> <time datetime="2020-01-02T12:00:00Z">January 2, 2020</time>, by NCI Staff </div> <p>NCI periodically provides updates on new websites and other online content of interest to the cancer community. See selected content that has been added as of January 2020.</p> <p><a href="/news-events/cancer-currents-blog/2020/new-online-january-2020">Continue Reading ></a></p> </div> </div> </li> </li> </ul> </div> <div class="blog-pager clearfix"> </div> </div> </div> </ul> </div> </div> </div> </div> <footer class="article-footer"> </footer> </article>  </div> </main> </div>   <div class="cgdpl desktop:grid-col-3"> <div id="nvcgSlListBlogRTRail" class="right-rail"> <div class="slot-item"> <div class="managed list with-date"> <h2 id="Featured+Posts">Featured Posts</h2> <ul> <li class="general-list-item general list-item"> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2024/medical-cannabis-oncologists-patients-communication">Oncologists Struggle to Answer Questions About Medical Cannabis</a> <div class="byline"> <p> October 16, 2024, by Carmen Phillips </p> </div> </div> </li> <li class="general-list-item general list-item"> <div 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id="blog-archive-accordion-year"> <h3> 2024 </h3> <ul class="ui-helper-reset"> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2024&month=11"> November </a> (5) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2024&month=10"> October </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2024&month=09"> September </a> (5) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2024&month=08"> August </a> (9) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2024&month=07"> July </a> (6) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2024&month=06"> June </a> (5) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2024&month=05"> May </a> (9) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2024&month=04"> April </a> (6) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2024&month=03"> March </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2024&month=02"> February </a> (6) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2024&month=01"> January </a> (6) </li> </ul> <h3> 2023 </h3> <ul class="ui-helper-reset"> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2023&month=12"> December </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2023&month=11"> November </a> (6) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2023&month=10"> October </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2023&month=09"> September </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2023&month=08"> August </a> (6) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2023&month=07"> July </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2023&month=06"> June </a> (8) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2023&month=05"> May </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2023&month=04"> April </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2023&month=03"> March </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2023&month=02"> February </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2023&month=01"> January </a> (6) </li> </ul> <h3> 2022 </h3> <ul class="ui-helper-reset"> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2022&month=12"> December </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2022&month=11"> November </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2022&month=10"> October </a> (5) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2022&month=09"> September </a> (6) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2022&month=08"> August </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2022&month=07"> July </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2022&month=06"> June </a> (8) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2022&month=05"> May </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2022&month=04"> April </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2022&month=03"> March </a> (8) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2022&month=02"> February </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2022&month=01"> January </a> (6) </li> </ul> <h3> 2021 </h3> <ul class="ui-helper-reset"> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2021&month=12"> December </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2021&month=11"> November </a> (4) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2021&month=10"> October </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2021&month=09"> September </a> (9) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2021&month=08"> August </a> (6) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2021&month=07"> July </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2021&month=06"> June </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2021&month=05"> May </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2021&month=04"> April </a> (8) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2021&month=03"> March </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2021&month=02"> February </a> (5) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2021&month=01"> January </a> (6) </li> </ul> <h3> 2020 </h3> <ul class="ui-helper-reset"> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2020&month=12"> December </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2020&month=11"> November </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2020&month=10"> October </a> (8) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2020&month=09"> September </a> (6) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2020&month=08"> August </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2020&month=07"> July </a> (9) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2020&month=06"> June </a> (8) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2020&month=05"> May </a> (8) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2020&month=04"> April </a> (10) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2020&month=03"> March </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2020&month=02"> February </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2020&month=01"> January </a> (7) </li> </ul> <h3> 2019 </h3> <ul class="ui-helper-reset"> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2019&month=12"> December </a> (6) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2019&month=11"> November </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2019&month=10"> October </a> (8) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2019&month=09"> September </a> (8) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2019&month=08"> August </a> (6) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2019&month=07"> July </a> (8) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2019&month=06"> June </a> (6) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2019&month=05"> May </a> (9) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2019&month=04"> April </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2019&month=03"> March </a> (10) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2019&month=02"> February </a> (9) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2019&month=01"> January </a> (6) </li> </ul> <h3> 2018 </h3> <ul class="ui-helper-reset"> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2018&month=12"> December </a> (9) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2018&month=11"> November </a> (9) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2018&month=10"> October </a> (9) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2018&month=09"> September </a> (11) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2018&month=08"> August </a> (9) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2018&month=07"> July </a> (9) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2018&month=06"> June </a> (12) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2018&month=05"> May </a> (9) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2018&month=04"> April </a> (10) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2018&month=03"> March </a> (11) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2018&month=02"> February </a> (11) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2018&month=01"> January </a> (10) </li> </ul> </div> </div> </div> </div> </div> </div>  </div> <section class="cgdp-page-options cgdp-page-options--bottom" aria-label="Page options bottom"> <button class="usa-button usa-button--unstyled" onclick="window.print()"> <svg xmlns="http://www.w3.org/2000/svg" height="24" viewBox="0 0 24 24" width="24" class="usa-icon" role="img" aria-hidden="true" focusable="false"> <path d="M0 0h24v24H0z" fill="none"/> <path d="M19 8H5c-1.66 0-3 1.34-3 3v6h4v4h12v-4h4v-6c0-1.66-1.34-3-3-3zm-3 11H8v-5h8v5zm3-7c-.55 0-1-.45-1-1s.45-1 1-1 1 .45 1 1-.45 1-1 1zm-1-9H6v4h12V3z"/> </svg> <span class="usa-sr-only"> Print </span> </button> <a class="usa-button usa-button--unstyled" 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January 2020 - Cancer Currents Blog - NCI