CINXE.COM

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<div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1120 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Paesi Bassi</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-netherlands">Nederlands</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1121 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Portogallo</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div 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paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Taiwan</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-taiwan">Traditional Chinese</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1126 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Regno Unito</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-uk">English</a></div> </div> </span> </div> </div> </div> </div> </section> </div> </div> </div> </div> </div> </div> </header> <div id="maindiv" class="container-fluid"> <main id="midcontent-area" class="column main-content"> <div id="content"> <div class="region region-content"> <div data-drupal-messages-fallback class="hidden"></div> <article data-history-node-id="690" role="article" about="/alnylam-switzerland-italian" class="clp full clearfix"> <div class="content"> <div class="field field--name-field-add-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--banner-with-text paragraph-id--1338 paragraph--view-mode--default"> <div class="paragraph paragraph--type--banner-with-text paragraph-id--1338 paragraph--view-mode--default"> <div id="simple-banner-with-text-wrapper" style="background: url(/sites/default/files/2022-05/CLP_header_slider_hero_1.jpg); background-size: cover; background-repeat: no-repeat;"> <div class="text-wrapper" style="width:1130px;margin:auto;"> <div class="upper-text"> <h2>A chi dice “impossibile, inattuabile, irrealistico,” rispondiamo:</h2> <h1>Sfida Accettata</h1> <p>Ci occupiamo dello sviluppo di un'innovativa classe di farmaci basata sulla tecnologia RNAi (interferenza dell'RNA), che ha il potenziale per migliorare in modo significativo la vita dei pazienti affetti da certe malattie rare.</p> </div> </div> </div> <div class="mobile-upper-text"> <h2>A chi dice “impossibile, inattuabile, irrealistico,” rispondiamo:</h2> <h1>Sfida Accettata</h1> <p>Ci occupiamo dello sviluppo di un'innovativa classe di farmaci basata sulla tecnologia RNAi (interferenza dell'RNA), che ha il potenziale per migliorare in modo significativo la vita dei pazienti affetti da certe malattie rare.</p> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--clp-banner-overlay paragraph-id--1340 paragraph--view-mode--default"> <div id="clp-banner-overlay"> <div class="banner-text-wrapper" style="width:1130px; margin:auto;"> <div class="text-box"> <section> <h1 class="text-align-center"><strong>IN PRIMA LINEA NEL CAMBIAMENTO </strong></h1> <p class="text-align-center">Basati su una ricerca vincitrice del premio Nobel, i farmaci RNAi rappresentano un convalidato approccio di grande efficacia per il trattamento di un’ampia gamma di malattie gravi e debilitanti. Alnylam è impegnata nell'applicazione dell'RNA interference (RNAi) a una nuova classe di farmaci innovativi per pazienti con opzioni terapeutiche limitate o inadeguate.</p> <p class="text-align-center">Fondata nel 2002, Alnylam persegue una visione coraggiosa per trasformare le potenzialità scientifiche in realtà, grazie ad un solido dipartimento di ricerca e una promettente pipeline di farmaci in fase di sperimentazione,tra cui cinque prodotti in fase avanzata di sviluppo, e quattro prodotti che sono già stati autorizzati dalla FDA negli Stati Uniti, dall'EMA in Europa e Swissmedic in Svizzera.</p> </section> <div class="counter-box"> <h3 class="text-center"> </h3> <div class="row"> <div class="col-sm-2"> <h1 class="text-align-center">><span>1k</span></h1> <p class="count-text text-align-center">Dipendenti</p> </div> <div class="col-sm-2"> <h1 class="text-align-center"><span>19</span></h1> <p class="count-text text-align-center">Paesi</p> </div> <div class="col-sm-2"> <h1 class="text-align-center"><span>11</span></h1> <p class="count-text text-align-center">Programmi attualmente in sviluppo clinico</p> </div> <div class="col-sm-2"> <h1 class="text-align-center"><span>4</span></h1> <p class="count-text text-align-center">Prodotti approvati</p> </div> <div class="col-sm-2"> <h1 class="text-align-center">><span>35</span></h1> <p class="count-text text-align-center">Studi clinici condotti fino a oggi</p> </div> <div class="col-sm-2"> <h1 class="text-align-center">><span>8</span></h1> <p class="count-text text-align-center">Maggiore durata di esposizione</p> </div> </div> <p class="text-center margin-top-24px"><em>aggiornato a Aprile 2022</em></p> </div> </div> </div> <div class=" popup-content" style="display:none; background:#fff;"> <div class="field field--name-field-pop-up-field field--type-entity-reference-revisions field--label-hidden field--item"> <div> </div> </div> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--clp-full-bleed-bg paragraph-id--1342 paragraph--view-mode--default"> <div class="paragraph paragraph--type--clp-full-bleed-bg paragraph-id--1342 paragraph--view-mode--default"> <div id="clp-full-bleed-bg" style="background: url(/sites/default/files/2022-01/bleed_2.jpg); background-size: cover; background-repeat: no-repeat;"> <div class="text-wrapper" style="width:900px;margin:auto;"> <h1 class="text-align-center"><strong>RNAi: UNA RIVOLUZIONE IN BIOLOGIA CHE NASCE DA una ricerca vincitrice del premio Nobel</strong></h1> <p class="text-align-center">L’interferenza dell’RNA (RNAi) è una svolta nella comprensione della regolazione dei geni nelle cellule. Il Premio Nobel per la Fisiologia o la Medicina del 2006, attribuito a Craig Mello e Andrew Fire, ha riconosciuto l’importanza fondamentale della scoperta dell’RNAi. Tale tecnologia rappresenta un approccio completamente innovativo alla scoperta e allo sviluppo dei farmaci. Rappresenta inoltre un approccio completamente diverso alla scoperta e allo sviluppo dei farmaci.</p> <p class="text-align-center"><a data-colorbox-inline=".cta-full-bleed-switzerland-italian">Maggiori informazioni ›</a></p> </div> <div class="cta-full-bleed-switzerland-italian popup-content" style="display:none; background:#fff; overflow:hidden;"> <div class="field field--name-field-pop-up-content field--type-entity-reference-revisions field--label-hidden field--item"> <div> <h2 class="text-center">STAI PER ESSERE REINDIRIZZATO</h2> <h4>Stai abbandonando www.alnylam.ch per visitare il nostro sito Internet globale (www.alnylam.com), in lingua inglese.</h4> <p class="text-center"> <a class="button-more" href="/our-science/the-science-of-rnai" target= "_blank">CONTINUE</a> </p> </div> </div> </div> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--clp-html-background paragraph-id--1344 paragraph--view-mode--default"> <div id="clp-html-content-background" style="background-color:#f8f8f8;"> <div class="content-wrapper" style="width:1130px; margin:auto; "> <div class="clp-html-background-desc"> <h2 class="text-align-center"><strong>I nostri obiettivi</strong></h2> <p class="text-align-center">La nostra pipeline di farmaci basati sulla tecnologia dell'RNAi si concentra su malattie con esigenze mediche ampiamente insoddisfatte in campo medico, appartenenti a 4 aree terapeutiche strategiche (Strategic Therapeutic Areas, STArs): malattie genetiche, malattie cardiometaboliche, malattie epatiche infettive, malattie del sistema nervoso centrale (SNC) e malattie oculari.</p> <p class="text-align-center">I nostri prodotti autorizzati per i pazienti in Svizzera sono utilizzati nel trattamento dell'amiloidosi ereditaria ATTR (hATTR) con polineuropatia, iperossaluria primitiva di tipo 1 (PH1) e porfiria epatica acuta (AHP). I nostri prodotti in fase avanzata di sviluppo (da Fase 2 a Fase 3) trattano principalmente l'amiloidosi ereditaria ATTR (hATTR), l'emofilia, l'ipercolesterolemia e le malattie mediate dal complemento.</p> </div> <div class="cta-html-background-switzerland-italian popup-content" style="display:none; background:#fff; overflow:hidden;"> <div class="field field--name-field-html-pop-up field--type-entity-reference-revisions field--label-hidden field--item"> <div> <h2 class="text-center">STAI PER ESSERE REINDIRIZZATO</h2> <h4>Stai abbandonando www.alnylam.ch per visitare il nostro sito Internet globale (www.alnylam.com), in lingua inglese.</h4> <p class="text-center"> <a class="button-more" href="/alnylam-rnai-pipeline" target= "_blank">CONTINUE</a> </p> </div> </div> </div> </div> <div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--clp-left-img-text paragraph-id--1346 paragraph--view-mode--default"> <div id="clp-left-img-text"> <div class="img-text-wrapper" style="width:1130px; margin:auto;"> <div class="img-box"> <div class="field field--name-field-upload-image field--type-image field--label-hidden field--item"> <img src="/sites/default/files/2022-05/cpl-svizzera-2022.png" width="696" height="405" alt="" loading="lazy" typeof="foaf:Image" class="img-responsive" /> </div> </div> <div class="text-box"> <h2><strong>Unisciti al nostro team </strong></h2> <p>Al fine di raggiungere il nostro obiettivo di diventare un'organizzazione commerciale in grado di fornire autonomamente i farmaci ai pazienti, siamo alla costante ricerca di risorse, e formazione diverse per aiutarci a costruire un team di livello mondiale. 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