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class="layout-columns__sidebar__content"> <h1 class="sidebar-heading"> <span class="sidebar-heading__subheading">Topic</span>Hearing Loss </h1> </div> </div> <div class="layout-columns__main -padding--vertical -padding--horizontal"> <div class="layout-columns__main__content"> <ul class="content-tease__list"> <li class="content-tease__item"> <div class="content-tease" itemtype="http://schema.org/ScholarlyArticle"> <p class="content-tease__topic"> <span class="highlight">Featured</span> </p> <h3 class="content-tease__heading" itemprop="name"> <a href="/otolaryngology/article.aspx?id=1505" itemprop="url"> An Estimate for Hidden Hearing Loss</a> </h3> <p itemprop="description"> <p><span>In one of the largest retrospective studies of its kind, a group of Mass Eye and Ear researchers examined data from nearly 96,000 ears to develop a word-score model that can help estimate the amount of hidden hearing loss in humans.</span></p></p> <p class="content-tease__related"> <a href="/otolaryngology/topic.aspx?id=1113" itemprop="relatedLink">Hearing Loss</a>, <a href="/otolaryngology/specialty.aspx?id=1016" itemprop="relatedLink">Otolaryngology</a> </p> <p class="content-metadata"> <span class="content-metadata__media -article">Article</span> <time class="date" datetime="2023-01-26" itemprop="datePublished">January 26, 2023</time> </p> </div> </li> <li class="content-tease__item"> <div class="content-tease" itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/research-and-innovation/q-a.aspx?id=1031" itemprop="url"> Innovations in Hearing and Vision Restoration Through Gene Therapy</a> </h3> <p itemprop="description"> <p>Artur A. Indzhykulian, MD, PhD, is advancing gene therapies for sensory disorders like Usher syndrome, exploring innovative approaches to restore hearing, balance, and vision through cutting-edge research and cross-disciplinary collaboration.</p></p> <p class="content-tease__related"> <a href="/research-and-innovation/topic.aspx?id=1114" itemprop="relatedLink">Gene and Cell Therapy</a>, <a href="/otolaryngology/topic.aspx?id=1113" itemprop="relatedLink">Hearing Loss</a>, <a href="/otolaryngology/specialty.aspx?id=1016" itemprop="relatedLink">Otolaryngology</a> </p> <p class="content-metadata"> <span class="content-metadata__media -qa">Q & A</span> <time class="date" datetime="2024-11-05" itemprop="datePublished">November 5, 2024</time> </p> </div> </li> <li class="content-tease__item"> <div class="content-tease" itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/otolaryngology/article.aspx?id=1576" itemprop="url"> Establishing a Nonsyndromic Hearing Loss Gene</a> </h3> <p itemprop="description"> <p>A robust collaboration between Mass Eye and Ear and Boston Children's Hospital resulted in discovering a novel gene for nonsyndromic hearing loss called PKHD1L1.</p></p> <p class="content-tease__related"> <a href="/otolaryngology/topic.aspx?id=1113" itemprop="relatedLink">Hearing Loss</a>, <a href="/otolaryngology/specialty.aspx?id=1016" itemprop="relatedLink">Otolaryngology</a> </p> <p class="content-metadata"> <span class="content-metadata__media -article">Article</span> <time class="date" datetime="2024-07-01" itemprop="datePublished">July 1, 2024</time> </p> </div> </li> <li class="content-tease__item"> <div class="content-tease" itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/otolaryngology/journal.aspx?id=2617" itemprop="url"> Cochlear Organoids Shed Light on Hair Cell Regeneration for Hearing Loss Treatment</a> </h3> <p itemprop="description"> <p>Albert Edge, PhD, and colleagues have developed murine cochlear organoids that show how sensory epithelial progenitor cells differentiate into hair cells, a potential step toward developing regenerative therapies for human hearing loss.</p></p> <p class="content-tease__related"> <a href="/research-and-innovation/topic.aspx?id=1114" itemprop="relatedLink">Gene and Cell Therapy</a>, <a href="/otolaryngology/topic.aspx?id=1113" itemprop="relatedLink">Hearing Loss</a>, <a href="/otolaryngology/specialty.aspx?id=1016" itemprop="relatedLink">Otolaryngology</a> </p> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2024-05-07" itemprop="datePublished">May 7, 2024</time> </p> </div> </li> <li class="content-tease__item"> <div class="content-tease" itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/otolaryngology/journal.aspx?id=2545" itemprop="url"> Virally Mediated Gene Therapy Treats Genetic Hearing Loss in Aged Mouse Model</a> </h3> <p itemprop="description"> <p><span>Zheng-Yi Chen, DPhil, and colleagues are the first to demonstrate rescue of genetic hearing loss with a gene therapy delivered by adeno-associated virus in an aged animal model. The study also serves as proof-of-principle that other gene therapies be developed for older adults.</span></p></p> <p class="content-tease__related"> <a href="/research-and-innovation/topic.aspx?id=1114" itemprop="relatedLink">Gene and Cell Therapy</a>, <a href="/otolaryngology/topic.aspx?id=1113" itemprop="relatedLink">Hearing Loss</a>, <a href="/otolaryngology/specialty.aspx?id=1016" itemprop="relatedLink">Otolaryngology</a> </p> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2023-11-01" itemprop="datePublished">November 1, 2023</time> </p> </div> </li> <li class="content-tease__item"> <div class="content-tease" itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/otolaryngology/journal.aspx?id=2291" itemprop="url"> Prior Surgery No Barrier to Cochlear Implantation for M茅ni猫re's Disease</a> </h3> <p itemprop="description"> <p><span>Steven D. Rauch, MD, and colleagues at Mass Eye and Ear found word recognition scores improve after cochlear implantation for deafness caused by Ménière's disease regardless of age at implantation and whether patients received previous medical or surgical Ménière's treatment.</span></p></p> <p class="content-tease__related"> <a href="/otolaryngology/topic.aspx?id=1113" itemprop="relatedLink">Hearing Loss</a>, <a href="/otolaryngology/specialty.aspx?id=1016" itemprop="relatedLink">Otolaryngology</a> </p> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2022-08-15" itemprop="datePublished">August 15, 2022</time> </p> </div> </li> </ui> <p class="fat-link__cta u-flush u-text-right"> <a class="fat-link -caret -large" href="https://advances.massgeneral.org/search.aspx?q=*&st=1&topic=hearing%20loss&maxResults=15">View all Hearing Loss updates</a> </p> </div> </div> </section> <section class="-background--grey -padding--vertical -padding--horizontal"> <div class="content-container -width--wide -centered"> <h2 class="section-heading -centered">Hearing Loss Contributors</h2> <ul class="profile-card__list" id="profile-cards"> <li class="profile-card" itemscope="" itemtype="http://schema.org/Person"> <div class="profile-card__content"> <p class="profile-card__content__image"> <img alt="" itemprop="image" srcset="/assets/images/contributors/albert_edge_advances.png, /assets/images/contributors/albert_edge_advances_2x.png 2x" src="/assets/images/contributors/albert_edge_advances.png"> </p> <h3 class="profile-card__name" itemprop="name"> <a href="/contributors/contributor.aspx?id=2178" itemprop="url">Albert Edge, PhD</a> </h3> <p itemprop="jobTitle"> Director, Tillotson Cell Biology Unit, Principal Investigator, Eaton-Peabody Laboratories, Mass Eye and Ear, Professor of Otolaryngology鈥揌ead and Neck Surgery, Harvard Medical School</p> <p class="profile-card__article"> <strong>Recent Article</strong><br> <a href="/otolaryngology/journal.aspx?id=2617">Cochlear Organoids Shed Light on Hair Cell Regeneration for Hearing Loss Treatment</a> </p> </div> <p class="profile-card__image"> <img alt="" itemprop="image" srcset="/assets/images/contributors/albert_edge_advances.png, /assets/images/contributors/albert_edge_advances_2x.png 2x" src="/assets/images/contributors/albert_edge_advances.png"> </p> </li> <li class="profile-card" itemscope="" itemtype="http://schema.org/Person"> <div class="profile-card__content"> <h3 class="profile-card__name" itemprop="name"> <a href="/contributors/contributor.aspx?id=2370" itemprop="url">David Y. Chung, MD, PhD</a> </h3> <p itemprop="jobTitle"> Attending Physician, Division of Neurocritical Units, Department of Neurology, Massachusetts General Hospital</p> <p class="profile-card__article"> <strong>Recent Article</strong><br> <a href="/neuro/journal.aspx?id=2352">Minimally Invasive Electrocorticography, Continuous EEG Do Not Reliably Detect Spreading Depolarizations</a> </p> </div> <p class="profile-card__image"> <img alt="" itemprop="image" srcset=", 2x" src=""> </p> </li> <li class="profile-card" itemscope="" itemtype="http://schema.org/Person"> <div class="profile-card__content"> <p class="profile-card__content__image"> <img alt="" itemprop="image" srcset="/assets/images/contributors/dunia_abdul_aziz_advances.png, /assets/images/contributors/dunia_abdul_aziz_advances_2x.png 2x" src="/assets/images/contributors/dunia_abdul_aziz_advances.png"> </p> <h3 class="profile-card__name" itemprop="name"> <a href="/contributors/contributor.aspx?id=2177" itemprop="url">Dunia Abdul-Aziz, MD</a> </h3> <p itemprop="jobTitle"> Physician-Surgeon, Mass Eye and Ear, Instructor in Otolaryngology鈥揌ead and Neck Surgery, Harvard Medical School</p> <p class="profile-card__article"> <strong>Recent Article</strong><br> <a href="/otolaryngology/journal.aspx?id=2146">Discovery of New Molecular Player May Lead to Pathway for Hearing Loss Reversal</a> </p> </div> <p class="profile-card__image"> <img alt="" itemprop="image" srcset="/assets/images/contributors/dunia_abdul_aziz_advances.png, /assets/images/contributors/dunia_abdul_aziz_advances_2x.png 2x" src="/assets/images/contributors/dunia_abdul_aziz_advances.png"> </p> </li> <li class="profile-card" itemscope="" itemtype="http://schema.org/Person"> <div class="profile-card__content"> <h3 class="profile-card__name" itemprop="name"> <a href="/contributors/contributor.aspx?id=2413" itemprop="url">St茅phane F. Maison, PhD, CCC-A</a> </h3> <p itemprop="jobTitle"> Principal Investigator, Eaton-Peabody Laboratories, Mass Eye and Ear, Associate Professor of Otolaryngology鈥揌ead and Neck Surgery, Harvard Medical School</p> <p class="profile-card__article"> <strong>Recent Article</strong><br> <a href="/otolaryngology/journal.aspx?id=2533">New Biomarker for Cochlear Nerve Degeneration Proposed</a> </p> </div> <p class="profile-card__image"> <img alt="" itemprop="image" srcset=", 2x" src=""> </p> </li> <li class="profile-card" itemscope="" itemtype="http://schema.org/Person"> <div class="profile-card__content"> <p class="profile-card__content__image"> <img alt="" itemprop="image" srcset="/assets/images/contributors/steven_rauch_advances.png, /assets/images/contributors/steven_rauch_advances_2x.png 2x" src="/assets/images/contributors/steven_rauch_advances.png"> </p> <h3 class="profile-card__name" itemprop="name"> <a href="/contributors/contributor.aspx?id=2328" itemprop="url">Steven D. Rauch, MD</a> </h3> <p itemprop="jobTitle"> Director, Vestibular Division, Medical Director, Balance and Vestibular Center, Massachusetts Eye and Ear, Professor of Otolaryngology鈥揌ead and Neck Surgery, Harvard Medical School</p> <p class="profile-card__article"> <strong>Recent Article</strong><br> <a href="/otolaryngology/journal.aspx?id=2291">Prior Surgery No Barrier to Cochlear Implantation for M茅ni猫re's Disease</a> </p> </div> <p class="profile-card__image"> <img alt="" itemprop="image" srcset="/assets/images/contributors/steven_rauch_advances.png, /assets/images/contributors/steven_rauch_advances_2x.png 2x" src="/assets/images/contributors/steven_rauch_advances.png"> </p> </li> </ul> <p class="fat-link__wrapper u-text-centered"> <button class="fat-link -plus -large" data-module="view-cards" data-target="#profile-cards" data-show="4">Hearing Loss Contributors</button> </p> </div> </section> <div class="content-container -width--xwide -centered specialty-block__wrapper" id="specialty-block"> <style> #specialty-block .specialty-block__image { /* 540px */ background-image: url(/assets/raw/specialty-block/otolaryngology-2-2400.png); } only screen and (-webkit-min-device-pixel-ratio: 2), only screen and (min--moz-device-pixel-ratio: 2), only screen and (-moz-min-device-pixel-ratio: 2), only screen and (-o-min-device-pixel-ratio: 2/1), only screen and (min-device-pixel-ratio: 2), only screen and (min-resolution: 192dpi), only screen and (min-resolution: 2dppx) { #specialty-block .specialty-block__image { /* 1080 width */ background-image: url(/assets/raw/specialty-block/otolaryngology-2-1200.png); } } /* </style> <span class="specialty-block__image"></span> <div class="specialty-block"> <h2 class="section-heading">Mass Eye and Ear/Mass General Otolaryngology鈥揌ead and Neck Surgery</h2> A teaching hospital of Harvard Medical School, Mass Eye and Ear/Massachusetts General Hospital combines the expertise of highly specialized ear, nose, and throat physicians, audiologists, speech-language pathologists and auxiliary health care professionals to provide care for patients with problems affecting the ear, nose, throat, head and neck areas. The department, which is led by Chief and Chair Mark A. Varvares, MD, FACS, is one of the largest otolaryngology鈥揾ead and neck surgery (OHNS) departments in the country, with more than 70 physicians staffed at 15 locations in the greater Boston area. <div class="specialty-block__meta"> <div class="specialty-block__links"> <h3 class="specialty-block__links__heading">Related Links</h3> <ul> <li><a href="https://www.masseyeandear.org/otolaryngology">Department of Otolaryngology鈥揌ead and Neck Surgery (OHNS)</a></li> <li><a href="https://www.masseyeandear.org/research/otolaryngology">OHNS Research</a></li> <li><a href="https://oto.hms.harvard.edu/">Harvard OHNS</a></li> </ul> </div> <div class="specialty-block__logos"> <ul> <li><a href="https://www.masseyeandear.org/"><img alt="Mass Eye and Ear" src="/assets/raw/specialty-block/MEE-Logo-2021-3.png"></a></li> </ul> </div> </div> </div> </div> <div class="-padding--horizontal -padding--vertical -background--white"> <style> #email-signup { /* 540px */ background-image: 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