Intervention Phase Achievements | Natural History Museum

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href="/our-science/our-work/sustainability/deworm3.html" onclick="CQ_Analytics.record({event:'followBreadcrumb',values: { breadcrumbPath: '/content/nhmwww/en/home/our-science/our-work/sustainability/deworm3' },collect: false,options: { obj: this },componentPath: 'nhmwww/components/includes/nhm-breadcrumb'})">DeWorm3</a> / <strong>Intervention Phase Achievements</strong> </div> </div> </div>  <div> <div class="layout-row"> <div class="layout-column"> <div class="title-bar " data-gtm-component="title"> <div class="title-bar__content flow"> <div class="repel"> <h1 class="title-bar__title">NHM Intervention Phase Achievements</h1> </div> <div class="cluster"> </div> </div> </div> </div> </div> </div> <div> <div class="row2cells21 section"> <div class="row" data-equalizer > <div class="large-8 medium-8 columns" data-equalizer-watch> <div class="par parsys"><div class="text parbase section"> <div data-gtm-component="text"> <p>The DeWorm3 Project is a collection of BMGF funded grants with interconnected objectives. Aligned to distinct study phases, the overarching goal is to determine the feasibility of STH transmission. The first phase, ‘The Intervention’ led by the Natural History Museum (2015-2021) sought to identify effective drug-delivery strategies to interrupt STH transmission by undertaking three years of twice-annual community-wide mass drug administration (MDA) with albendazole as compared to the standard national STH control strategy in each trial country (Fig. 1).</p> </div> </div> <div class="foundation5image parbase section"> <div> <figure class=" flow" role="group"> <picture> <source media="(max-width: 480px)" srcset="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3InterventionTimeline.jpg.placeholder.480.480.png" data-srcset="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3InterventionTimeline.jpg.thumb.480.480.jpg"/> <source media="(min-width: 481px)" srcset="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3InterventionTimeline.jpg.placeholder.768.768.png" data-srcset="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3InterventionTimeline.jpg.thumb.768.768.jpg"/> <img class="lazy" src="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3InterventionTimeline.jpg.placeholder.768.768.png" data-src="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3InterventionTimeline.jpg.thumb.768.768.jpg" alt="Fig. 1: The DeWorm3 Intervention Timeline."/> </picture> <figcaption> <div class="image--caption-container" data-caption-truncation> <div class="image--caption"> <p>Fig. 1: The DeWorm3 Intervention Timeline.</p> </div> </div> </figcaption> </figure> </div> </div> <div class="text parbase section"> <div data-gtm-component="text"> <p>Study areas with target populations between 80,000 and 110,000 were selected in each site. Following complete enumeration of the population of each study site, clusters were demarcated within the study area (Fig. 2). Following cluster demarcation, stool samples were collected from a random subset of individuals for baseline STH prevalence assessment and randomization of the clusters. Following randomization, clusters received either twice-annual community-wide MDA or standard-of-care school-age-targeted deworming (per national guidelines in each country) for three years.</p> </div> </div> <div class="foundation5image parbase section"> <div> <figure class=" flow" role="group"> <picture> <source media="(max-width: 480px)" srcset="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3StudyClusters.jpg.placeholder.480.480.png" data-srcset="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3StudyClusters.jpg.thumb.480.480.jpg"/> <source media="(min-width: 481px)" srcset="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3StudyClusters.jpg.placeholder.768.768.png" data-srcset="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3StudyClusters.jpg.thumb.768.768.jpg"/> <img class="lazy" src="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3StudyClusters.jpg.placeholder.768.768.png" data-src="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3StudyClusters.jpg.thumb.768.768.jpg" alt="Fig. 2: Study clusters and households enumerated in India, Malawi and Benin. "/> </picture> <figcaption> <div class="image--caption-container" data-caption-truncation> <div class="image--caption"> <p>Fig. 2: Study clusters and households enumerated in India, Malawi and Benin. </p> </div> </div> </figcaption> </figure> </div> </div> <div class="text parbase section"> <div data-gtm-component="text"> <p>As of December 2020, all Intervention Phase activities have been completed, with <b>annual censuses (Fig. 3) enumerating approximately 260,000 households and 1,065,000 individuals across three sites over three years.</b></p> <p>Annual longitudinal monitoring (LMC) and a baseline Cross-Sectional Survey (CSS) resulted in approximately <b>93,000 stool samples being collected and stored for future analysis</b> in the next phases of the project.</p> <p>Similarly, all six rounds of planned MDA and subsequent coverages surveys have been delivered in India, Malawi and Benin with <b>890,134 albendazole doses being distributed to eligible participants.</b></p> <p>With consistently high coverage and a stalwart reputation amongst local communities, the DeWorm3 project is<b> </b>significantly contributing towards the global targets of eliminating STH as a public health problem. Through DeWorm3, the Natural History Museum has championed collaboration, capacity-building<b> </b>and<b> </b>exceptional research governance, and<b> </b>is proud of its legacy as leader upon the successful completion of Phase 1 of DeWorm3.</p> <p><a href="http://depts.washington.edu/deworm3/" target="_blank" aria-describedby="new-window" title="UW">Click here</a> for the next phase of DeWorm3. </p> </div> </div> <div class="foundation5image parbase section"> <div> <figure class=" flow" role="group"> <picture> <source media="(max-width: 480px)" srcset="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DW3_Census.jpg.placeholder.480.480.png" data-srcset="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DW3_Census.jpg.thumb.480.480.jpg"/> <source media="(min-width: 481px)" srcset="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DW3_Census.jpg.placeholder.768.768.png" data-srcset="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DW3_Census.jpg.thumb.768.768.jpg"/> <img class="lazy" src="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DW3_Census.jpg.placeholder.768.768.png" data-src="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DW3_Census.jpg.thumb.768.768.jpg" alt="Fig. 3: Demographics of the trial Censuses. "/> </picture> <figcaption> <div class="image--caption-container" data-caption-truncation> <div class="image--caption"> <p>Fig. 3: Demographics of the trial Censuses. </p> </div> </div> </figcaption> </figure> </div> </div> </div> </div> <div class="large-4 medium-4 columns" data-equalizer-watch> <div class="par2 parsys"><div class="foundation5image parbase section"> <div> <figure class=" flow" role="group"> <picture> <source media="(max-width: 480px)" srcset="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/eDataCollectionPiloting.jpg.placeholder.480.480.png" data-srcset="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/eDataCollectionPiloting.jpg.thumb.480.480.jpg"/> <source media="(min-width: 481px)" srcset="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/eDataCollectionPiloting.jpg.placeholder.768.768.png" data-srcset="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/eDataCollectionPiloting.jpg.thumb.768.768.jpg"/> <img class="lazy" src="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/eDataCollectionPiloting.jpg.placeholder.768.768.png" data-src="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/eDataCollectionPiloting.jpg.thumb.768.768.jpg" alt="DeWorm3 has fostered a positive relationship with the local communities. "/> </picture> <figcaption> <div class="image--caption-container" data-caption-truncation> <div class="image--caption"> <p>DeWorm3 has fostered a positive relationship with the local communities. </p> </div> </div> </figcaption> </figure> </div> </div> <div class="foundation5image parbase section"> <div> <figure class=" flow" role="group"> <picture> <source media="(max-width: 480px)" srcset="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/Malawi_SBD3.jpg.placeholder.480.480.png" data-srcset="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/Malawi_SBD3.jpg.thumb.480.480.jpg"/> <source media="(min-width: 481px)" srcset="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/Malawi_SBD3.jpg.placeholder.768.768.png" data-srcset="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/Malawi_SBD3.jpg.thumb.768.768.jpg"/> <img class="lazy" src="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/Malawi_SBD3.jpg.placeholder.768.768.png" data-src="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/Malawi_SBD3.jpg.thumb.768.768.jpg" alt="Malawi SBD3"/> </picture> <figcaption> <div class="image--caption-container" data-caption-truncation> <div class="image--caption"> <p>School children being treated with albendazole in Malawi.</p> </div> </div> </figcaption> </figure> </div> </div> </div> </div> </div> </div> </div> </div> <footer class="main-footer" data-gtm-component="footer"> <div class="layout-row " data-columns="4" id="layoutcontainer-4d1df0ecd9"> <div class="layout-column flow"> <div class="foundation5image parbase"> <div> <figure class="main-footer--logo flow" role="group"> <img src="/content/dam/nhmwww/press-office/nhm-logo-white.svg" alt="Natural History Museum logo"/> </figure> </div> </div> <div class="text parbase"> <div data-gtm-component="text"> <h3><a href="https://www.nhm.ac.uk/">The Natural History Museum</a></h3> <p><b>Cromwell Road</b></p> <p><b>London SW7 5BD</b></p> <p><b><a href="https://www.google.co.uk/maps/place/Natural+History+Museum/@51.4967183,-0.1785559,17z/data=!3m2!4b1!5s0x4876055d2a62ace7:0xf1f051390954c55!4m5!3m4!1s0x48760542e6182f3f:0x7bb7e385c39764c4!8m2!3d51.496715!4d-0.1763672?hl=en">Map</a></b></p> <p>Open daily 10.00-17.50<br /> (last entry 17.30)<br /> Closed 24-26 December</p> <p><a href="/visit.html">Plan your visit</a></p> <p> </p> <h3><a href="/visit/tring.html">The Natural History Museum at Tring</a><br /> </h3> <p><b>Akeman Street</b></p> <p><b>Tring</b></p> <p><b>Hertfordshire HP23 6AP</b></p> <p><a href="https://www.google.co.uk/maps/place/Natural+History+Museum+at+Tring/@51.7907453,-0.6634277,17z/data=!3m1!4b1!4m5!3m4!1s0x48765bdea86d0a7d:0x169a990130daab9a!8m2!3d51.790742!4d-0.661239?hl=en">Map</a></p> <p>Open Tuesday-Sunday and bank holidays<br /> 10.00-17.00 (last entry 16.00)<br /> Closed 24-26 December</p> <p><a href="/visit/tring.html">Plan your visit to Tring</a> </p> </div> </div> </div> <div class="layout-column flow"> <div class="list-wrapper"> <div class="list list--footer"> <h2> <a href="/visit.html"> Visit </a> </h2> <ul> <li> <a href="/visit/whats-on.html"> What's on </a> </li> <li> <a href="/visit/galleries-and-museum-map.html"> Galleries and Museum map </a> </li> <li> <a href="/visit/access-at-south-kensington.html"> Access </a> </li> </ul> </div> </div> <div class="list-wrapper"> <div class="list list--footer"> <h2> <a href="/discover.html"> Discover </a> </h2> <ul> <li> <a href="/discover/news.html"> News </a> </li> <li> <a href="/discover/anthropocene.html"> Anthropocene </a> </li> <li> <a href="/discover/british-wildlife.html"> British wildlife </a> </li> <li> <a href="/discover/collections.html"> Collections </a> </li> <li> <a href="/discover/dinosaurs.html"> Dinosaurs </a> </li> <li> <a href="/discover/human-evolution.html"> Human evolution </a> </li> <li> <a href="/discover/oceans.html"> Oceans </a> </li> <li> <a href="/discover/space.html"> Space </a> </li> <li> <a href="/discover/what-on-earth.html"> What on Earth? 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