CINXE.COM

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protein 4 (RBP4) is a Lipocalin superfamily molecule that transports vitamin A (retinol) and retinaldehyde in the serum.<span class="text_more collapsed"> Retinaldehyde is the critical chromophore in the rhodopsin photoreceptor, while both it and retinoic acid regulate a multitude of cellular differentiation and proliferation effects through the intracellular receptors RAR and RXR. RBP4 is secreted primarily by hepatocytes and adipocytes into the blood where the RBP4-retinol complex interacts with transthyretin (TTR). Formation of the complex with TTR increases the serum half-life of RBP4 by preventing RBP4 filtration through the kidney. The C-terminally processed forms of RBP4, which do not bind TTR, are normally excreted into the urine but accumulate in the serum during renal failure. RBP4 promotes hyperglycemia, and its upregulation in visceral and liver adipocytes leads to elevated serum levels.</p> </span></p> <div class="cnsp-show-more-wrapper"><div class="cnsp-show-more collapsed">Show More</div></div> </div></div> <div class="search_header"> "<span class="search_term">RBP4/Retinol-Binding Protein 4</span>" has 5 results in Products. </div> <div class="search_type"> Sort by: <div class="select_wrapper"><select id="search_type_select">'; <option value="/target/rbp4-retinol-binding-protein-4?rnd_applications=ELISA&sort=ranking,desc" selected="selected"> Best Match </option> <option value="/target/rbp4-retinol-binding-protein-4?rnd_applications=ELISA&sort=product_title,asc"> Products (A-Z) </option> <option value="/target/rbp4-retinol-binding-protein-4?rnd_applications=ELISA&sort=product_added,desc"> Newest </option> <option value="/target/rbp4-retinol-binding-protein-4?rnd_applications=ELISA&sort=stars,desc"> Rating </option> </select></div>  </div>  </div>  <div class="cnsp-result search_result search_product"> <h2><a href="/products/human-rbp4-quantikine-elisa-kit_drb400" class="ecommerce_link" data-id="DRB400" data-variant="DRB400" data-search_type="target_search" data-position="1" data-brand="rnd" data-name="Human RBP4 Quantikine ELISA Kit" data-category="ELISAs" data-sub_category="Quantikine Colorimetric Sandwich ELISAs" data-sub_category_id="28" data-price="635" data-currency_code="USD">Human RBP4 Quantikine ELISA Kit</a> </h2> <div class="cnsp-description"> </div> <div class="cnsp_content"> <div class="cnsp_table"> <div class="cnsp_table_row"> <div class="cnsp_meta"> <div class="cnsp_catnum"><a href="/products/human-rbp4-quantikine-elisa-kit_drb400">DRB400</a></div> <div class="cnsp_citations"><a href="/products/human-rbp4-quantikine-elisa-kit_drb400#product-citations">30 Citations</a></div> <a data-toggle="lightbox" data-gallery="DRB400" data-title="Human RBP4/Retinol-Binding Protein 4 ELISA Standard Curve" 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