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Amaurosis - Wikipedia
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id="toc-Leber's_congenital_amaurosis" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Leber's_congenital_amaurosis"> <div class="vector-toc-text"> <span class="vector-toc-numb">1.1</span> <span>Leber's congenital amaurosis</span> </div> </a> <ul id="toc-Leber's_congenital_amaurosis-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Amaurosis_fugax" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Amaurosis_fugax"> <div class="vector-toc-text"> <span class="vector-toc-numb">1.2</span> <span>Amaurosis fugax</span> </div> </a> <ul id="toc-Amaurosis_fugax-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Quinidine_toxicity" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Quinidine_toxicity"> <div class="vector-toc-text"> <span class="vector-toc-numb">1.3</span> <span>Quinidine toxicity</span> </div> </a> <ul id="toc-Quinidine_toxicity-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Management" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Management"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Management</span> </div> </a> <ul id="toc-Management-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-In_animals" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#In_animals"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>In animals</span> </div> </a> <ul id="toc-In_animals-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-References" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#References"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>References</span> </div> </a> <ul id="toc-References-sublist" class="vector-toc-list"> </ul> </li> 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German" lang="de" hreflang="de" data-title="Amaurose" data-language-autonym="Deutsch" data-language-local-name="German" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Amaurosis" title="Amaurosis – Spanish" lang="es" hreflang="es" data-title="Amaurosis" data-language-autonym="Español" data-language-local-name="Spanish" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Amaurose" title="Amaurose – French" lang="fr" hreflang="fr" data-title="Amaurose" data-language-autonym="Français" data-language-local-name="French" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-io mw-list-item"><a href="https://io.wikipedia.org/wiki/Amauroso" title="Amauroso – Ido" lang="io" hreflang="io" data-title="Amauroso" 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<div class="mw-indicators"> </div> <div id="siteSub" class="noprint">From Wikipedia, the free encyclopedia</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="en" dir="ltr"><div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">Loss of vision</div> <p><b>Amaurosis</b> (Greek meaning <i>darkening</i>, <i>dark</i>, or <i>obscure</i>) is <a href="/wiki/Vision_loss" class="mw-redirect" title="Vision loss">vision loss</a> or weakness that occurs without an apparent lesion affecting the <a href="/wiki/Human_eye" title="Human eye">eye</a>.<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> It may result from either a medical condition or excess acceleration, as in flight. The term is the same as the <a href="/wiki/Latin_language" class="mw-redirect" title="Latin language">Latin</a> <i>gutta serena</i>, which means, in Latin, <i>clear drop</i> (or <i>bright drop</i>). <i>Gutta serena</i> is a condition of partial or complete blindness with a transparent, clear pupil. This term contrasts with <i>suffusio nigra</i> which means, in Latin, <i>dark suffusion</i>, indicating partial or complete blindness with a dark pupil, e.g., a cataract. Milton, already totally blind for twelve years (some scholars think from retinal detachment; others have diagnosed glaucoma) by the time he published <a href="/wiki/Paradise_Lost" title="Paradise Lost">Paradise Lost</a>, refers to these terms in Book 3, lines 25–26.<sup id="cite_ref-The_Encyclopedia_of_World_Problems_f832_2-0" class="reference"><a href="#cite_note-The_Encyclopedia_of_World_Problems_f832-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Types">Types</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Amaurosis&action=edit&section=1" title="Edit section: Types"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading3"><h3 id="Leber's_congenital_amaurosis"><span id="Leber.27s_congenital_amaurosis"></span>Leber's congenital amaurosis</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Amaurosis&action=edit&section=2" title="Edit section: Leber's congenital amaurosis"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1236090951">.mw-parser-output .hatnote{font-style:italic}.mw-parser-output div.hatnote{padding-left:1.6em;margin-bottom:0.5em}.mw-parser-output .hatnote i{font-style:normal}.mw-parser-output .hatnote+link+.hatnote{margin-top:-0.5em}@media print{body.ns-0 .mw-parser-output .hatnote{display:none!important}}</style><div role="note" class="hatnote navigation-not-searchable">Main article: <a href="/wiki/Leber%27s_congenital_amaurosis" class="mw-redirect" title="Leber's congenital amaurosis">Leber's congenital amaurosis</a></div> <p>Leber's congenital amaurosis (LCA) is the most severe and earliest of the inherited retinal dystrophies that cause congenital blindness. It has an incidence of 2-3 per 100,000 births and accounts for 10-18% of cases of congenital blindness among children in blind institutes and 5% of all retinal dystrophies, a figure that is likely to be greater in countries with a greater percentage of consanguinity.<sup id="cite_ref-Fazzi_Signorini_Scelsa_Bova_2003_pp._13–22_3-0" class="reference"><a href="#cite_note-Fazzi_Signorini_Scelsa_Bova_2003_pp._13–22-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> </p><p>In most cases, LCA is inherited in an autosomal recessive pattern, as established by Alström and Olson in 1957. Some patients only have retinal blindness, whereas others have multi-systemic involvement that includes renal, cardiac, skeletal, and, most notably, central nervous system anomalies.<sup id="cite_ref-Fazzi_Signorini_Scelsa_Bova_2003_pp._13–22_3-1" class="reference"><a href="#cite_note-Fazzi_Signorini_Scelsa_Bova_2003_pp._13–22-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> </p><p>Theodor von Leber, a German ophthalmologist, described LCA in 1869 as a disorder characterized by profound visual loss present at or shortly after birth, nystagmus, sluggish pupillary reactions, and pigmentary retinopathy.<sup id="cite_ref-Fazzi_Signorini_Scelsa_Bova_2003_pp._13–22_3-2" class="reference"><a href="#cite_note-Fazzi_Signorini_Scelsa_Bova_2003_pp._13–22-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Amaurosis_fugax">Amaurosis fugax</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Amaurosis&action=edit&section=3" title="Edit section: Amaurosis fugax"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951"><div role="note" class="hatnote navigation-not-searchable">Main article: <a href="/wiki/Amaurosis_fugax" title="Amaurosis fugax">Amaurosis fugax</a></div> <p>Amaurosis fugax, also known as transient monocular blindness, is caused by a sudden, temporary decrease in blood flow to one eye. The loss of vision is abrupt, lasting only seconds or minutes. Blindness is total, though it is sometimes limited to a specific area of vision. Blindness frequently develops as if a shade was drawn upward or downward over the eye, rarely sideward. Single or multiple attacks are possible. Some patients experience hundreds, if not thousands, of episodes. Pain, scintillations, and diplopia are usually not present. The prognosis for retinal recovery is good in most patients; retinal infarction occurs in a few.<sup id="cite_ref-Gautier_1993_pp._426–428_4-0" class="reference"><a href="#cite_note-Gautier_1993_pp._426–428-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Quinidine_toxicity">Quinidine toxicity</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Amaurosis&action=edit&section=4" title="Edit section: Quinidine toxicity"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951"><div role="note" class="hatnote navigation-not-searchable">Main article: <a href="/wiki/Quinidine" title="Quinidine">Quinidine</a></div> <p>Although amaurosis caused by quinine poisoning is now uncommon, it does occur on occasion. When quinine is used as an abortifacient, the initial history may be deceptive, but the presence of characteristic changes in the fundi usually allows certainty of a diagnosis.<sup id="cite_ref-Drance_1955_pp._178–181_5-0" class="reference"><a href="#cite_note-Drance_1955_pp._178–181-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Management">Management</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Amaurosis&action=edit&section=5" title="Edit section: Management"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1251242444">.mw-parser-output .ambox{border:1px solid #a2a9b1;border-left:10px solid #36c;background-color:#fbfbfb;box-sizing:border-box}.mw-parser-output .ambox+link+.ambox,.mw-parser-output .ambox+link+style+.ambox,.mw-parser-output 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.reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-1">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20080303194648/http://www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspzQzpgzEzzSzppdocszSzuszSzcommonzSzdorlandszSzdorlandzSzdmd_a_27zPzhtm">"Dorlands Medical Dictionary"</a>. Archived from <a rel="nofollow" class="external text" href="http://www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspzQzpgzEzzSzppdocszSzuszSzcommonzSzdorlandszSzdorlandzSzdmd_a_27zPzhtm">the original</a> on 2008-03-03<span class="reference-accessdate">. Retrieved <span class="nowrap">2005-09-25</span></span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Dorlands+Medical+Dictionary&rft_id=http%3A%2F%2Fwww.mercksource.com%2Fpp%2Fus%2Fcns%2Fcns_hl_dorlands.jspzQzpgzEzzSzppdocszSzuszSzcommonzSzdorlandszSzdorlandzSzdmd_a_27zPzhtm&rfr_id=info%3Asid%2Fen.wikipedia.org%3AAmaurosis" class="Z3988"></span></span> </li> <li id="cite_note-The_Encyclopedia_of_World_Problems_f832-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-The_Encyclopedia_of_World_Problems_f832_2-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://encyclopedia.uia.org/en/problem/amaurosis">"Amaurosis"</a>. <i>The Encyclopedia of World Problems</i><span class="reference-accessdate">. Retrieved <span class="nowrap">2023-11-04</span></span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=The+Encyclopedia+of+World+Problems&rft.atitle=Amaurosis&rft_id=http%3A%2F%2Fencyclopedia.uia.org%2Fen%2Fproblem%2Famaurosis&rfr_id=info%3Asid%2Fen.wikipedia.org%3AAmaurosis" class="Z3988"></span></span> </li> <li id="cite_note-Fazzi_Signorini_Scelsa_Bova_2003_pp._13–22-3"><span class="mw-cite-backlink">^ <a href="#cite_ref-Fazzi_Signorini_Scelsa_Bova_2003_pp._13–22_3-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Fazzi_Signorini_Scelsa_Bova_2003_pp._13–22_3-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-Fazzi_Signorini_Scelsa_Bova_2003_pp._13–22_3-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFFazziSignoriniScelsaBova2003" class="citation journal cs1">Fazzi, Elisa; Signorini, Sabrina Giovanna; Scelsa, Barbara; Bova, Stefania Maria; Lanzi, Giovanni (2003). "Leber's congenital amaurosis: an update". <i>European Journal of Paediatric Neurology</i>. <b>7</b> (1). Elsevier BV: 13–22. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fs1090-3798%2802%2900135-6">10.1016/s1090-3798(02)00135-6</a>. <a href="/wiki/ISSN_(identifier)" class="mw-redirect" title="ISSN (identifier)">ISSN</a> <a rel="nofollow" class="external text" href="https://search.worldcat.org/issn/1090-3798">1090-3798</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/12615170">12615170</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=European+Journal+of+Paediatric+Neurology&rft.atitle=Leber%27s+congenital+amaurosis%3A+an+update&rft.volume=7&rft.issue=1&rft.pages=13-22&rft.date=2003&rft.issn=1090-3798&rft_id=info%3Apmid%2F12615170&rft_id=info%3Adoi%2F10.1016%2Fs1090-3798%2802%2900135-6&rft.aulast=Fazzi&rft.aufirst=Elisa&rft.au=Signorini%2C+Sabrina+Giovanna&rft.au=Scelsa%2C+Barbara&rft.au=Bova%2C+Stefania+Maria&rft.au=Lanzi%2C+Giovanni&rfr_id=info%3Asid%2Fen.wikipedia.org%3AAmaurosis" class="Z3988"></span></span> </li> <li id="cite_note-Gautier_1993_pp._426–428-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-Gautier_1993_pp._426–428_4-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFGautier1993" class="citation journal cs1">Gautier, Jean-Claude (1993-08-05). "Amaurosis Fugax". <i>New England Journal of Medicine</i>. <b>329</b> (6). Massachusetts Medical Society: 426–428. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1056%2Fnejm199308053290611">10.1056/nejm199308053290611</a>. <a href="/wiki/ISSN_(identifier)" class="mw-redirect" title="ISSN (identifier)">ISSN</a> <a rel="nofollow" class="external text" href="https://search.worldcat.org/issn/0028-4793">0028-4793</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/8326979">8326979</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=New+England+Journal+of+Medicine&rft.atitle=Amaurosis+Fugax&rft.volume=329&rft.issue=6&rft.pages=426-428&rft.date=1993-08-05&rft.issn=0028-4793&rft_id=info%3Apmid%2F8326979&rft_id=info%3Adoi%2F10.1056%2Fnejm199308053290611&rft.aulast=Gautier&rft.aufirst=Jean-Claude&rfr_id=info%3Asid%2Fen.wikipedia.org%3AAmaurosis" class="Z3988"></span></span> </li> <li id="cite_note-Drance_1955_pp._178–181-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-Drance_1955_pp._178–181_5-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFDrance1955" class="citation journal cs1">Drance, S. M. (1955-03-01). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1324536">"Quinine Amaurosis"</a>. <i>British Journal of Ophthalmology</i>. <b>39</b> (3). BMJ: 178–181. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1136%2Fbjo.39.3.178">10.1136/bjo.39.3.178</a></span>. <a href="/wiki/ISSN_(identifier)" class="mw-redirect" title="ISSN (identifier)">ISSN</a> <a rel="nofollow" class="external text" href="https://search.worldcat.org/issn/0007-1161">0007-1161</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1324536">1324536</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/14363615">14363615</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=British+Journal+of+Ophthalmology&rft.atitle=Quinine+Amaurosis&rft.volume=39&rft.issue=3&rft.pages=178-181&rft.date=1955-03-01&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1324536%23id-name%3DPMC&rft.issn=0007-1161&rft_id=info%3Apmid%2F14363615&rft_id=info%3Adoi%2F10.1136%2Fbjo.39.3.178&rft.aulast=Drance&rft.aufirst=S.+M.&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1324536&rfr_id=info%3Asid%2Fen.wikipedia.org%3AAmaurosis" class="Z3988"></span></span> </li> </ol></div></div> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r1236075235">.mw-parser-output .navbox{box-sizing:border-box;border:1px solid #a2a9b1;width:100%;clear:both;font-size:88%;text-align:center;padding:1px;margin:1em auto 0}.mw-parser-output .navbox .navbox{margin-top:0}.mw-parser-output .navbox+.navbox,.mw-parser-output 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dt:first-child::before,.mw-parser-output .hlist dd li:first-child::before,.mw-parser-output .hlist dt dd:first-child::before,.mw-parser-output .hlist dt dt:first-child::before,.mw-parser-output .hlist dt li:first-child::before,.mw-parser-output .hlist li dd:first-child::before,.mw-parser-output .hlist li dt:first-child::before,.mw-parser-output .hlist li li:first-child::before{content:" (";font-weight:normal}.mw-parser-output .hlist dd dd:last-child::after,.mw-parser-output .hlist dd dt:last-child::after,.mw-parser-output .hlist dd li:last-child::after,.mw-parser-output .hlist dt dd:last-child::after,.mw-parser-output .hlist dt dt:last-child::after,.mw-parser-output .hlist dt li:last-child::after,.mw-parser-output .hlist li dd:last-child::after,.mw-parser-output .hlist li dt:last-child::after,.mw-parser-output .hlist li li:last-child::after{content:")";font-weight:normal}.mw-parser-output .hlist ol{counter-reset:listitem}.mw-parser-output .hlist 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