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expires=' + expires.toGMTString() + '; domain=.' + this.getMasterDomain() + ';'; }, /** * get the master domain based on business rules */ getMasterDomain : function () { // default the master domain var masterDomain = 'thermofisher.com'; // check for alternate domain portion of URL var regexMatch = document.location.hostname.match(/\.(thermofisher)\.(cn)/i); if (regexMatch !== null) { masterDomain = regexMatch[1] + '.' + regexMatch[2]; } return masterDomain; }, /** * Check if init has been initiated once * @type {Boolean} */ initted: false, /** * @return {Array} method returns an array of a given object's key properties */ init: function () { this.page.country = this.getCookie("CK_ISO_CODE") || 'us'; this.page.language = this.getCookie('CK_LANG_CODE') || 'en'; this.page.siteName = 'thermo'; //hard coded this.initMerchandisingData(); this.initUserData(); this.displayDigitalData(); this.formSubmitEvent(); }, //specific function to set type of the page // need specific function to keep page type separate from other page attributes setPageType: function (type) { this.setPageAttribute('type', type); 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max-width: 230px; } </style><script type="text/javascript"> $( document ).ready(function() { // apply fillIt plugin var fillClasses = "#cq-image-jsp-"+"66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysimage_ec6b .image-contain" + "," + "#cq-image-jsp-"+"66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysimage_ec6b .image-cover" ; // Due to the issue explained below, we are binding 'one' instead of 'on' and we need it only once. $(fillClasses).load(function() { $(this).fillIt(); }); // Force load image to avoid cache issue, a bug which makes image reset height when having more than one image/image-text components on the same page and rendering after edit. $(fillClasses).each(function(){ if(this.complete){ $(this).load(); } }); if(!!window.picturefill){ window.picturefill(); } }); </script></div></div></div></div><div class="parsys_column cq-colctrl-lt8-c1"><div container-id="cq-colctrl-lt8" comp-id="B1"><div class="heading section"><h2> Fast, simple, reproducible protein digestion in about an hour </h2></div></div><div container-id="cq-colctrl-lt8" comp-id="B2"><div class="text parbase section"><p>Use the latest advance in protein digestion for peptide mapping and quantitation applications. Thermo Scientific SMART Digest Kits make protein digestion:</p><ul><li>Fast</li><li>Simple</li><li>Reproducible</li><li>Easy to automate</li></ul></div></div></div></div><div style="clear:both"></div><div class="text parbase section"><p>Protein digestion kits use optimized heat-stable enzymes on magnetic or non-magnetic beads. Immunoaffinity (IA) kits couple enzymatic digestion with IA capture on a single bead for high sensitivity. This innovation generates high confidence in your HPLC and LC/MS results, and it can be automated. SMART Digest Kits especially benefit biomarker and biopharmaceutical characterization and quantitation applications.</p></div><div comp-order="bycol" class="parsys_column cq-colctrl-lt3"><div class="parsys_column cq-colctrl-lt3-c0"><div container-id="cq-colctrl-lt3" comp-id="A1"><div class="well-cmp section"><div class="well well-gray-light well-default"><div class="well-container" style=""><div class="well-content"><div class="parsys"><div class="heading section"><h2> Fast, easy, reproducible </h2></div><div class="text parbase section"><ul><li>Simple 3-step protocol</li><li>Process samples in hours instead of days</li><li>Better reproducibility than in-solution digestion</li></ul></div></div></div></div></div></div></div></div><div class="parsys_column cq-colctrl-lt3-c1"><div container-id="cq-colctrl-lt3" comp-id="B1"><div class="well-cmp section"><div class="well well-gray-light well-default"><div class="well-container" style=""><div class="well-content"><div class="parsys"><div class="heading section"><h2> Immunoaffinity (IA) capture </h2></div><div class="text parbase section"><ul><li>Enzymatic digestion with IA capture</li><li>Higher throughput</li><li>Greater sensitivity<br>  </li></ul></div></div></div></div></div></div></div></div><div class="parsys_column cq-colctrl-lt3-c2"><div container-id="cq-colctrl-lt3" comp-id="C1"><div class="well-cmp section"><div class="well well-gray-light well-default"><div class="well-container" style=""><div class="well-content"><div class="parsys"><div class="heading section"><h2> Automate it<br>  </h2></div><div class="text parbase section"><ul><li>KingFisher Duo Prime purification system</li><li><span class="icon-lt-pdf"></span> <a href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/AN-21682-SP-LC-MS-Peptide-Mapping-Proteins-AN21682-EN.pdf" target="_blank">Automating peptide mapping</a></li><li><a href="/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest.html?open=automate-digestion">Learn more</a></li></ul></div></div></div></div></div></div></div></div></div><div style="clear:both"></div><div class="text parbase section"><p><a href="/sg/en/home/global/forms/industrial/smart-digest-contact-request.html"><span class="btn btn-featured">Contact us</span></a>   <a href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/an-21878-smart-digest-compendium-an21878-en.pdf"><span class="btn btn-primary">Application Note Compendium</span></a></p></div><div class="divider section"><hr /></div><div class="heading section"><h2> SMART Digest protein digestion kits for peptide mapping and peptide quantitation </h2></div><div class="accordion section"><div class="accordion" id="3cd92ff4c09542b0b8fd7ecbfd418bfb" style='margin-bottom: 0;'><div class="parsys"><div class="accordionitem section"><div class='accordion-group' ><div class='accordion-heading '><a class="accordion-toggle" data-toggle="collapse" data-parent="#3cd92ff4c09542b0b8fd7ecbfd418bfb" href="#smartdigestkits"><span class="caret"></span> SMART Digest kits: trypsin, chymotrypsin, pepsin or proteinase K protein digestion </a></div><div class="accordion-body collapse " id="smartdigestkits"><div class="accordion-inner"><div class="accordion-content"><div class="itemParsys parsys"><div class="heading section"><h3> SMART Digest kits: trypsin, chymotrypsin, or proteinase K protein digestion </h3></div><div class="text parbase section"><p>Choose between optimized heat-stable trypsin, chymotrypsin, or proteinase K enzymatic digestion for sequence-specific cleavage of your protein. The enzyme, on magnetic or non-magnetic beads, is activated at elevated temperatures for accelerated digestion under protein denaturing conditions.</p><ul><li>Trypsin cleaves the C-terminal side of lysine and arginine amino acid residues</li><li>Chymotrypsin cleaves the peptide bonds formed by aromatic residues such as tyrosine, phenylalanine, and tryptophan</li><li>Pepsin preferentially cleaves hydrophobic, preferably aromatic, residues in P1 and P1' positions. It will also preferentially cleave at the carboxyl side of phenylalanine and leucine and at the carboxyl side of glutamic acid residues</li><li>Proteinase K cleaves the peptide bond adjacent to the carboxyl group of aliphatic and aromatic amino acids with blocked alpha amino groups</li></ul><ul class="the-icons clearfix"><li><span class="icon-lt-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/CMD/manuals/Man-21543-SMART-Digest-User-Man21543-EN.pdf" target="_blank">SMART Digest User Manual</a></li></ul></div><div class="text parbase section"><h4>PCR options</h4><div class="table-component-wrapper"><table class="rte-table" id="table--1351039242"><tbody><tr><th> </th><th>Catalog</th><th>Description</th><th>Each Kit Includes</th></tr><tr><td><a href="/order/catalog/product/60109-101">Order now</a></td><td><a href="/order/catalog/product/60109-101">60109-101</a></td><td>SMART DIGEST KIT Trypsin</td><td>96 PCR tubes containing SMART Digest Resin<br> Collection Plate</td></tr><tr><td><a href="/order/catalog/product/60109-104">Order now</a></td><td><a href="/order/catalog/product/60109-104">60109-104</a></td><td>SMART DIGEST KIT Chymotrypsin</td><td>96 PCR tubes containing SMART Digest Resin<br> Collection Plate</td></tr><tr><td><a href="/order/catalog/product/60109-107">Order now</a></td><td><a href="/order/catalog/product/60109-107">60109-107</a></td><td>SMART DIGEST KIT Proteinase K</td><td>96 PCR tubes containing SMART Digest Resin<br> Collection Plate</td></tr><tr><td><a href="/order/catalog/product/60109-110">Order now</a></td><td><a href="/order/catalog/product/60109-110">60109-110</a></td><td>SMART DIGEST KIT Pepsin</td><td>96 PCR tubes containing SMART Digest Resin<br> Collection Plate</td></tr><tr><th colspan="4"> </th></tr><tr><td><a href="/order/catalog/product/60109-102">Order now</a></td><td><a href="/order/catalog/product/60109-102">60109-102</a></td><td>SMART DIGEST KIT Trypsin</td><td>96 PCR tubes containing SMART Digest Resin<br> Collection Plate<br> 96 Well Filter plate</td></tr><tr><td><a href="/order/catalog/product/60109-105">Order now</a></td><td><a href="/order/catalog/product/60109-105">60109-105</a></td><td>SMART DIGEST KIT Chymotrypsin</td><td>96 PCR tubes containing SMART Digest Resin<br> Collection Plate<br> 96 Well Filter plate</td></tr><tr><td><a href="/order/catalog/product/60109-108">Order now</a></td><td><a href="/order/catalog/product/60109-108">60109-108</a></td><td>SMART DIGEST KIT Proteinase K</td><td>96 PCR tubes containing SMART Digest Resin<br> Collection Plate<br> 96 Well Filter plate</td></tr><tr><td><a href="/order/catalog/product/60109-111">Order now</a></td><td><a href="/order/catalog/product/60109-111">60109-111</a></td><td>SMART DIGEST KIT Pepsin</td><td>96 PCR tubes containing SMART Digest Resin<br> Collection Plate<br> 96 Well Filter plate</td></tr><tr><th colspan="4"> </th></tr><tr><td><a href="/order/catalog/product/60109-103">Order now</a></td><td><a href="/order/catalog/product/60109-103">60109-103</a></td><td>SMART DIGEST KIT Trypsin</td><td>96 PCR tubes containing SMART Digest Resin<br> Collection Plate<br> SOLAµ 96 Well SPE microelution plate</td></tr><tr><td><a href="/order/catalog/product/60109-106">Order now</a></td><td><a href="/order/catalog/product/60109-106">60109-106</a></td><td>SMART DIGEST KIT Chymotrypsin</td><td>96 PCR tubes containing SMART Digest Resin<br> Collection Plate<br> SOLAµ 96 Well SPE microelution plate</td></tr><tr><td><a href="/order/catalog/product/60109-109">Order now</a></td><td><a href="/order/catalog/product/60109-109">60109-109</a></td><td>SMART DIGEST KIT Proteinase K</td><td>96 PCR tubes containing SMART Digest Resin<br> Collection Plate<br> SOLAµ 96 Well SPE microelution plate</td></tr><tr><td><a href="/order/catalog/product/60109-112">Order now</a></td><td><a href="/order/catalog/product/60109-112">60109-112</a></td><td>SMART DIGEST KIT Pepsin</td><td>96 PCR tubes containing SMART Digest Resin<br> Collection Plate<br> SOLAµ 96 Well SPE microelution plate</td></tr></tbody></table></div></div><div class="heading section"><h4> Magnetic bulk options </h4></div><div class="text parbase section"><div class="table-component-wrapper"><table class="rte-table" id="table-1654672078"><tbody><tr><th> </th><th>Catalogue</th><th>Description</th><th>Each kit Includes</th></tr><tr><td><a href="/order/catalog/product/60109-101">Order now</a></td><td><a href="/order/catalog/product/60109-101">60109-101-MB</a></td><td>SMART Digest Kit Trypsin</td><td rowspan="4"><ul><li>Bulk SMART Digest resin</li><li>SMART Digest buffer</li></ul></td></tr><tr><td><a href="/order/catalog/product/60109-104">Order now</a></td><td><a href="/order/catalog/product/60109-104">60109-104-MB</a></td><td>SMART Digest Kit Chymotrypsin</td></tr><tr><td><a href="/order/catalog/product/60109-107">Order now</a></td><td><a href="/order/catalog/product/60109-107">60109-107-MB</a></td><td>SMART Digest Kit Proteinase K</td></tr><tr><td><a href="/order/catalog/product/60109-110">Order now</a></td><td><a href="/order/catalog/product/60109-110">60109-110-MB</a></td><td>SMART Digest Kit Pepsin</td></tr><tr><th> </th><th> </th><th> </th><th> </th></tr><tr><td><a href="/order/catalog/product/60109-101">Order now</a></td><td><a href="/order/catalog/product/60109-101">60109-102-MB</a></td><td>SMART Digest Kit Trypsin</td><td rowspan="3"><ul><li>Bulk SMART Digest resin</li><li>SMART Digest buffer</li><li>Collection plate</li><li>Filter plate</li></ul></td></tr><tr><td><a href="/order/catalog/product/60109-104">Order now</a></td><td><a href="/order/catalog/product/60109-104">60109-105-MB</a></td><td>SMART Digest Kit Chymotrypsin</td></tr><tr><td><a href="/order/catalog/product/60109-107">Order now</a></td><td><a href="/order/catalog/product/60109-107">60109-108-MB</a></td><td>SMART Digest Kit Proteinase K</td></tr><tr><th> </th><th> </th><th> </th><th> </th></tr><tr><td><a href="/order/catalog/product/60109-101">Order now</a></td><td><a href="/order/catalog/product/60109-101">60109-103-MB</a></td><td>SMART Digest Kit Trypsin</td><td rowspan="3"><ul><li>Bulk SMART Digest resin</li><li>SMART Digest buffer</li><li>Collection plate</li><li>SOLAμ SPE plate</li></ul></td></tr><tr><td><a href="/order/catalog/product/60109-104">Order now</a></td><td><a href="/order/catalog/product/60109-104">60109-106-MB</a></td><td>SMART Digest Kit Chymotrypsin</td></tr><tr><td><a href="/order/catalog/product/60109-107">Order now</a></td><td><a href="/order/catalog/product/60109-107">60109-109-MB</a></td><td>SMART Digest Kit Proteinase K</td></tr></tbody></table></div></div><div class="heading section"><h4> Non-magnetic bulk options </h4></div><div class="text parbase section"><div class="table-component-wrapper"><table class="rte-table" id="table-1843837397"><tbody><tr><th> </th><th>Catalogue</th><th>Description</th><th>Kits Include</th></tr><tr><td><a href="/order/catalog/product/60109-101-B">Order now</a></td><td><a href="/order/catalog/product/60109-101-B">60109-101-B</a></td><td>SMART Digest Kit Trypsin</td><td rowspan="4"><ul><li>Bulk SMART Digest resin</li><li>SMART Digest buffer</li></ul></td></tr><tr><td><a href="/order/catalog/product/60109-104-B">Order now</a></td><td><a href="/order/catalog/product/60109-104-B">60109-104-B</a></td><td>SMART Digest Kit Chymotrypsin</td></tr><tr><td><a href="/order/catalog/product/60109-107-B">Order now</a></td><td><a href="/order/catalog/product/60109-107-B">60109-107-B</a></td><td>SMART Digest Kit Proteinase K</td></tr><tr><td><a href="/order/catalog/product/60109-110-B">Order now</a></td><td><a href="/order/catalog/product/60109-110-B">60109-110-B</a></td><td>SMART Digest Kit Pepsin</td></tr><tr><th> </th><th> </th><th> </th><th> </th></tr><tr><td><a href="/order/catalog/product/60109-102-B">Order now</a></td><td><a href="/order/catalog/product/60109-102-B">60109-102-B</a></td><td>SMART Digest Kit Trypsin</td><td rowspan="3"><ul><li>Bulk SMART Digest resin</li><li>SMART Digest buffer</li><li>Collection plate</li><li>Filter plate</li></ul></td></tr><tr><td><a href="/order/catalog/product/60109-105-B">Order now</a></td><td><a href="/order/catalog/product/60109-105-B">60109-105-B</a></td><td>SMART Digest Kit Chymotrypsin</td></tr><tr><td><a href="/order/catalog/product/60109-108-B">Order now</a></td><td><a href="/order/catalog/product/60109-108-B">60109-108-B</a></td><td>SMART Digest Kit Proteinase K</td></tr><tr><th> </th><th> </th><th> </th><th> </th></tr><tr><td><a href="/order/catalog/product/60109-103-B">Order now</a></td><td><a href="/order/catalog/product/60109-103-B">60109-103-B</a></td><td>SMART Digest Kit Trypsin</td><td rowspan="3"><ul><li>Bulk SMART Digest resin</li><li>SMART Digest buffer</li><li>Collection plate</li><li>SOLAμ SPE plate</li></ul></td></tr><tr><td><a href="/order/catalog/product/60109-106-B">Order now</a></td><td><a href="/order/catalog/product/60109-106-B">60109-106-B</a></td><td>SMART Digest Kit Chymotrypsin</td></tr><tr><td><a href="/order/catalog/product/60109-109-B">Order now</a></td><td><a href="/order/catalog/product/60109-109-B">60109-109-B</a></td><td>SMART Digest Kit Proteinase K</td></tr></tbody></table></div></div><div class="heading section"><h4> Soluble enzyme option (for use with complex sample sets) </h4></div><div class="text parbase section"><div class="table-component-wrapper"><table class="rte-table" id="table--2146984314"><tbody><tr><th width="15%"> </th><th width="15%">Catalogue</th><th>Description</th><th>Kits Include</th></tr><tr><td><a href="/order/catalog/product/60113-101">Order now</a></td><td><a href="/order/catalog/product/60113-101">60113-101</a></td><td>SMART Digest Kit Soluble Trypsin</td><td><ul><li>SMART Digest soluble trypsin</li><li>SMART Digest buffer</li></ul></td></tr></tbody></table></div></div><div class="text parbase section"><h4>SMART Digest Bulk Fractionation Kits</h4><div class="table-component-wrapper"><table class="rte-table rte-table-striped" border="0" id="table-1100445812"><tbody><tr><th width="15%"> </th><th width="15%">Catalogue</th><th>Description</th></tr><tr><td><a href="/order/catalog/product/60114-101">Order now</a></td><td><a href="/order/catalog/product/60114-101">60114-101</a></td><td>SMART Digest Bulk Fractionation Kit, Protein A Non-Magnetic & Soluble Smart</td></tr><tr><td><a href="/order/catalog/product/60115-101">Order now</a></td><td><a href="/order/catalog/product/60115-101">60115-101</a></td><td>SMART Digest Bulk Fractionation Kit, Protein G Non-Magnetic & Soluble Smart</td></tr><tr><td><a href="/order/catalog/product/60114-102">Order now</a></td><td><a href="/order/catalog/product/60114-102">60114-102</a></td><td>SMART Digest Bulk Fractionation Kit, Protein A Non-Magnetic with SOLAµ/Collection plate & Soluble Smart</td></tr><tr><td><a href="/order/catalog/product/60115-102">Order now</a></td><td><a href="/order/catalog/product/60115-102">60115-102</a></td><td>SMART Digest Bulk Fractionation Kit, Protein G Non Magnetic with SOLAµ/Collection plate & Soluble Smart</td></tr><tr><td><a href="/order/catalog/product/60114-103">Order now</a></td><td><a href="/order/catalog/product/60114-103">60114-103</a></td><td>SMART Digest Bulk Fractionation Kit, Protein A Magnetic with SOLAµ/Collection plate  & SOLUBLE SMART</td></tr><tr><td><a href="/order/catalog/product/60115-103">Order now</a></td><td><a href="/order/catalog/product/60115-103">60115-103</a></td><td>SMART Digest Bulk Fractionation Kit, Protein G Magnetic with SOLAµ/Collection plate & Soluble smart</td></tr><tr><td><a href="/order/catalog/product/60114-104">Order now</a></td><td><a href="/order/catalog/product/60114-104">60114-104</a></td><td>SMART Digest Bulk Fractionation Kit, Protein A Magnetic & Soluble Smart</td></tr><tr><td><a href="/order/catalog/product/60115-104">Order now</a></td><td><a href="/order/catalog/product/60115-104">60115-104</a></td><td>SMART Digest Bulk Fractionation Kit, Protein G Magnetic & Soluble Smart</td></tr><tr><td><a href="/order/catalog/product/60116-101">Order now</a></td><td><a href="/order/catalog/product/60116-101">60116-101</a></td><td>SMART Digest Bulk Fractionation Kit, Protein A Magnetic standalone</td></tr><tr><td><a href="/order/catalog/product/60117-101">Order now</a></td><td><a href="/order/catalog/product/60117-101">60117-101</a></td><td>SMART Digest Bulk Fractionation Kit, Protein G Magnetic standalone</td></tr><tr><td><a href="/order/catalog/product/60118-101">Order now</a></td><td><a href="/order/catalog/product/60118-101">60118-101</a></td><td>SMART Digest Bulk Fractionation Kit Streptavidin Magnetic without Soluble Trypsin</td></tr><tr><td><a href="/order/catalog/product/60119-103">Order now</a></td><td><a href="/order/catalog/product/60119-103">60119-103</a></td><td>SMART Digest Bulk Fractionation Kit Streptavidin Magnetic with Soluble Trypsin, Collection plate and SOLAu</td></tr><tr><td><a href="/order/catalog/product/60119-104">Order now</a></td><td><a href="/order/catalog/product/60119-104">60119-104</a></td><td>SMART Digest Bulk Fractionation Kit Streptavidin Magnetic with Soluble Trypsin</td></tr></tbody></table></div></div></div></div></div></div></div></div><div class="accordionitem section"><div class='accordion-group' ><div class='accordion-heading '><a class="accordion-toggle" data-toggle="collapse" data-parent="#3cd92ff4c09542b0b8fd7ecbfd418bfb" href="#smartdigesttubekits"><span class="caret"></span> SMART Digest Kits: low pH for MAM workflows </a></div><div class="accordion-body collapse " id="smartdigesttubekits"><div class="accordion-inner"><div class="accordion-content"><div class="itemParsys parsys"><div class="text parbase section"><h3>SMART Digest Kits: low pH for MAM workflows</h3><h4>PCR options</h4><div class="table-component-wrapper"><table class="rte-table" id="table--1120677917"><tbody><tr><th> </th><th>Catalogue</th><th>Description</th><th>Each Kit Includes</th></tr><tr><td><a href="/order/catalog/product/60109-101-LPH">Order now</a></td><td><a href="/order/catalog/product/60109-101-LPH">60109-101-LPH</a></td><td>SMART DIGEST low pH KIT Trypsin</td><td>96 PCR tubes containing SMART Digest Resin<br> Collection Plate</td></tr></tbody></table></div><h4>Magnetic bulk options</h4><div class="table-component-wrapper"><table class="rte-table" id="table-257449832"><tbody><tr><th> </th><th>Catalogue</th><th>Description</th><th>Each Kit Includes</th></tr><tr><td><a href="/order/catalog/product/60109-101-MB-LPH">Order now</a></td><td><a href="/order/catalog/product/60109-101-MB-LPH">60109-101-MB-LPH</a></td><td>SMART DIGEST low pH KIT Trypsin Magnetic beads</td><td>96 PCR tubes containing SMART Digest Resin<br> Collection Plate</td></tr><tr><td><a href="/order/catalog/product/60109-104-MB-LPH">Order now</a></td><td><a href="/order/catalog/product/60109-104-MB-LPH">60109-104-MB-LPH</a></td><td>SMART DIGEST KIT CHYMOTRYPSIN Magnetic bulk low pH buffer</td><td>96 PCR tubes containing SMART Digest Resin<br> Collection Plate</td></tr></tbody></table></div><h4>Bulk options</h4><div class="table-component-wrapper"><table class="rte-table" id="table--1737282742"><tbody><tr><th> </th><th>Catalogue</th><th>Description</th><th>Each Kit Includes</th></tr><tr><td><a href="/order/catalog/product/60109-101-MB-LPH">Order now</a></td><td><a href="/order/catalog/product/60109-101-MB-LPH">60109-101-MB-LPH</a></td><td>SMART DIGEST low pH KIT Trypsin Magnetic beads</td><td>96 PCR tubes containing SMART Digest Resin<br> Collection Plate</td></tr><tr><td><a href="/order/catalog/product/60109-104-MB-LPH">Order now</a></td><td><a href="/order/catalog/product/60109-104-MB-LPH">60109-104-MB-LPH</a></td><td>SMART DIGEST KIT CHYMOTRYPSIN Magnetic bulk low pH buffer</td><td>96 PCR tubes containing SMART Digest Resin<br> Collection Plate</td></tr></tbody></table></div></div></div></div></div></div></div></div><div class="accordionitem section"><div class='accordion-group' ><div class='accordion-heading '><a class="accordion-toggle" data-toggle="collapse" data-parent="#3cd92ff4c09542b0b8fd7ecbfd418bfb" href="#smartdigestiakits"><span class="caret"></span> SMART Digest IA kits: trypsin digestion with immunoaffinity capture </a></div><div class="accordion-body collapse " id="smartdigestiakits"><div class="accordion-inner"><div class="accordion-content"><div class="itemParsys parsys"><div class="heading section"><h3> SMART Digest IA Kits: trypsin digestion with immunoaffinity (IA) capture (streptavidin, protein A, protein G) </h3></div><div class="text parbase section"><p>SMART Digest IA Kits perform trypsin digestion with immunoaffinity capture in a single well. The immunoaffinity moiety (streptavidin, protein A, or protein G) is typically employed to increase sensitivity by purifying your low-level proteins from complex biological matrices.</p><ul class="the-icons clearfix"><li><span class="icon-lt-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/CMD/manuals/Man-21549-SMART-Digest-IA-User-Man21549-EN.pdf" target="_blank">SMART Digest ImmunoAffinity (IA) Kit User Manual</a></li></ul></div><div class="heading section"><h4> Streptavidin (Av) </h4></div><div class="text parbase section"><div class="table-component-wrapper"><table class="rte-table" id="table--771141637"><tbody><tr><th style="width: 65px;"> </th><th>Catalogue</th><th>Description</th></tr><tr><td><a href="/order/catalog/product/60110-101">Order now</a></td><td><a href="/order/catalog/product/60110-101">60110-101</a></td><td>SMART Digest IA Kit, Streptavidin non-magnetic</td></tr><tr><td><a href="/order/catalog/product/60110-102">Order now</a></td><td><a href="/order/catalog/product/60110-102">60110-102</a></td><td>SMART Digest IA Kit, Streptavidin non-magnetic with Thermo Scientific SOLAµ SPE and collection plate</td></tr><tr><td><a href="/order/catalog/product/60110-103">Order now</a></td><td><a href="/order/catalog/product/60110-103">60110-103</a></td><td>SMART Digest IA Kit, Streptavidin magnetic with SOLAµ SPE and collection plate</td></tr><tr><td><a href="/order/catalog/product/60110-104">Order now</a></td><td><a href="/order/catalog/product/60110-104">60110-104</a></td><td>SMART Digest IA Kit, Streptavidin magnetic</td></tr></tbody></table></div></div><div class="heading section"><h4> Protein A </h4></div><div class="text parbase section"><div class="table-component-wrapper"><table class="rte-table" id="table--1890619076"><tbody><tr><th style="width: 65px;"> </th><th>Catalogue</th><th>Description</th></tr><tr><td><a href="/order/catalog/product/60111-101">Order now</a></td><td><a href="/order/catalog/product/60111-101">60111-101</a></td><td>SMART Digest IA Kit, Protein A non-magnetic</td></tr><tr><td><a href="/order/catalog/product/60111-102">Order now</a></td><td><a href="/order/catalog/product/60111-102">60111-102</a></td><td>SMART Digest IA Kit, Protein A non-magnetic with SOLAµ SPE and collection plate</td></tr><tr><td><a href="/order/catalog/product/60111-103">Order now</a></td><td><a href="/order/catalog/product/60111-103">60111-103</a></td><td>SMART Digest IA Kit, Protein A magnetic with SOLAµ SPE and collection plate</td></tr><tr><td><a href="/order/catalog/product/60111-104">Order now</a></td><td><a href="/order/catalog/product/60111-104">60111-104</a></td><td>SMART Digest IA Kit, Protein A magnetic</td></tr></tbody></table></div></div><div class="heading section"><h4> Protein G </h4></div><div class="text parbase section"><div class="table-component-wrapper"><table class="rte-table" id="table--1759845497"><tbody><tr><th style="width: 65px;"> </th><th>Catalogue</th><th>Description</th></tr><tr><td><a href="/order/catalog/product/60112-101">Order now</a></td><td><a href="/order/catalog/product/60112-101">60112-101</a></td><td>SMART Digest IA Kit, Protein G non-magnetic</td></tr><tr><td><a href="/order/catalog/product/60112-102">Order now</a></td><td><a href="/order/catalog/product/60112-102">60112-102</a></td><td>SMART Digest IA Kit, Protein G non-magnetic with SOLAµ SPE and collection plate</td></tr><tr><td><a href="/order/catalog/product/60112-103">Order now</a></td><td><a href="/order/catalog/product/60112-103">60112-103</a></td><td>SMART Digest IA Kit, Protein G magnetic with SOLAµ SPE and collection plate</td></tr><tr><td><a href="/order/catalog/product/60112-104">Order now</a></td><td><a href="/order/catalog/product/60112-104">60112-104</a></td><td>SMART Digest IA Kit, Protein G magnetic</td></tr></tbody></table></div></div></div></div></div></div></div></div><div class="accordionitem section"><div class='accordion-group' ><div class='accordion-heading '><a class="accordion-toggle" data-toggle="collapse" data-parent="#3cd92ff4c09542b0b8fd7ecbfd418bfb" href="#RNase"><span class="caret"></span> SMART RNase kits: fast and simple mRNA digestion </a></div><div class="accordion-body collapse " id="RNase"><div class="accordion-inner"><div class="accordion-content"><div class="itemParsys parsys"><div class="heading section"><h3> SMART RNase kits: fast and simple mRNA digestion </h3></div><div class="text parbase section"><p>Obtain high-quality analytical results from mRNA digestions using SMART Digest RNase Kits. A significant advance in sample preparation for oligonucleotide mapping and quantitation, these kits provide fast and simple mRNA digestion with high reproducibility, high sensitivity, and high levels of data quality in a format that is compatible with automation.</p></div><div class="text parbase section"><div class="table-component-wrapper"><table class="rte-table" id="table-309638048"><tbody><tr><th> </th><th>Catalogue</th><th>Description</th><th>Includes</th></tr><tr><td><a href="/order/catalog/product/60120-101">Order now</a></td><td><a href="/order/catalog/product/60120-101">60120-101</a></td><td>Bulk Magnetic SMART Digest Resin RNase T1</td><td>Bulk Magnetic SMART Digest Resin, SMART Digest Buffer</td></tr><tr><td><a href="/order/catalog/product/60120-102">Order now</a></td><td><a href="/order/catalog/product/60120-102">60120-102</a></td><td>Bulk Magnetic SMART Digest Resin RNase A</td><td>Bulk Magnetic SMART Digest Resin, SMART Digest Buffer</td></tr></tbody></table></div></div></div></div></div></div></div></div></div></div><script> $j(document).ready(function(){ $j('#3cd92ff4c09542b0b8fd7ecbfd418bfb').on('hide', function(e) { $(e.target).find(".accordion-content").hide(); }); $j('#3cd92ff4c09542b0b8fd7ecbfd418bfb').on('show', function(e) { $(e.target).find(".accordion-content").show(); }); }); </script></div><div class="divider section"><hr /></div><div class="heading section"><h2> Learn more about SMART Digest </h2></div><div class="accordion section"><div class="accordion" id="da4342d29e1f495fa0f58de85d5e6d44" style='margin-bottom: 0;'><div class="parsys"><div class="accordionitem section"><div class='accordion-group' ><div class='accordion-heading '><a class="accordion-toggle" data-toggle="collapse" data-parent="#da4342d29e1f495fa0f58de85d5e6d44" href="#3stepprotocol"><span class="caret"></span> Easy 3-step protocol </a></div><div class="accordion-body collapse " id="3stepprotocol"><div class="accordion-inner"><div class="accordion-content"><div class="itemParsys parsys"><div class="heading section"><h3> Easy 3-step protocol </h3></div><div class="image parbase section"><div id="cq-image-jsp-66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_4509itemParsysimage_b378"><a class="image-enlarge-link" data-lightbox="image_b378" href="/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/_jcr_content/MainParsys/accordion_7b4d/itemspar/accordionitem_4509/itemParsys/image_b378/backgroundimg.img.jpg/1694120178238.jpg"><picture><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4509/itemParsys/image_b378/foregroundimg.img.320.low.jpg/1694120178221.jpg' media="(min-width: 1px)"><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4509/itemParsys/image_b378/foregroundimg.img.320.medium.jpg/1694120178221.jpg' media="(min-width: 320px)"><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4509/itemParsys/image_b378/foregroundimg.img.480.medium.jpg/1694120178221.jpg' media="(min-width: 490px)"><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4509/itemParsys/image_b378/foregroundimg.img.620.high.jpg/1694120178221.jpg' media="(min-width: 630px)"><img srcset="https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4509/itemParsys/image_b378/foregroundimg.img.full.high.jpg/1694120178221.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4509/itemParsys/image_b378/foregroundimg.img.320.high.jpg/1694120178221.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4509/itemParsys/image_b378/foregroundimg.img.480.high.jpg/1694120178221.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4509/itemParsys/image_b378/foregroundimg.img.320.medium.jpg/1694120178221.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4509/itemParsys/image_b378/foregroundimg.img.620.high.jpg/1694120178221.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4509/itemParsys/image_b378/foregroundimg.img.320.low.jpg/1694120178221.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4509/itemParsys/image_b378/foregroundimg.img.480.medium.jpg/1694120178221.jpg" alt='Easy 3-step protocol' title='Easy 3-step protocol'></picture><style> #cq-image-jsp-66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_4509itemParsysimage_b378 img{ width:100%; max-width: 1000px; } </style><script type="text/javascript"> $( document ).ready(function() { // apply fillIt plugin var fillClasses = "#cq-image-jsp-"+"66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_4509itemParsysimage_b378 .image-contain" + "," + "#cq-image-jsp-"+"66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_4509itemParsysimage_b378 .image-cover" ; // Due to the issue explained below, we are binding 'one' instead of 'on' and we need it only once. $(fillClasses).load(function() { $(this).fillIt(); }); // Force load image to avoid cache issue, a bug which makes image reset height when having more than one image/image-text components on the same page and rendering after edit. $(fillClasses).each(function(){ if(this.complete){ $(this).load(); } }); if(!!window.picturefill){ window.picturefill(); } }); </script></a><div class="caption"><small><small><span class="icon-zoom-in"></span> Click image to enlarge</small></small></div></div></div><div class="well-cmp well-default well-blue-light section"><div class="well well-blue-light well-default"><div class="well-container" style=""><div class="well-content"><div class="parsys"><div class="heading section"><h4> Learn more </h4></div><div class="text parbase section"><ul class="the-icons clearfix"><li><span class="icon-lt-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/CMD/manuals/Man-21543-SMART-Digest-User-Man21543-EN.pdf" target="_blank">Manual: SMART Digest Kit – User Manual</a><u></u></li><li><span class="icon-lt-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/CMD/manuals/Man-21549-SMART-Digest-IA-User-Man21549-EN.pdf" target="_blank">Manual: SMART Digest ImmunoAffinity (IA) Kit – User Manual</a><u></u></li><li><span class="icon-lt-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/CMD/brochures/BR-72040-Peptide-Mapping-Workflows-BR72040-EN.pdf" target="_blank">Workflow: Upgrade Your Peptide Mapping Workflows</a></li></ul></div></div></div></div></div></div></div></div></div></div></div></div><div class="accordionitem section"><div class='accordion-group' ><div class='accordion-heading '><a class="accordion-toggle" data-toggle="collapse" data-parent="#da4342d29e1f495fa0f58de85d5e6d44" href="#comparemethods"><span class="caret"></span> Compare SMART Digest and in-solution methods </a></div><div class="accordion-body collapse " id="comparemethods"><div class="accordion-inner"><div class="accordion-content"><div class="itemParsys parsys"><div class="heading section"><h2> Compare SMART Digest and in-solution techniques — SMART Digest saves time </h2></div><div class="heading section"><h3> In-solution protein digestion </h3></div><div class="image parbase section"><div id="cq-image-jsp-66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_4672itemParsysimage_79a4"><picture><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4672/itemParsys/image_79a4/foregroundimg.img.320.medium.jpg/1694120178313.jpg' media="(min-width: 1px)"><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4672/itemParsys/image_79a4/foregroundimg.img.480.high.jpg/1694120178313.jpg' media="(min-width: 490px)"><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4672/itemParsys/image_79a4/foregroundimg.img.620.high.jpg/1694120178313.jpg' media="(min-width: 630px)"><img srcset="https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4672/itemParsys/image_79a4/foregroundimg.img.full.high.jpg/1694120178313.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4672/itemParsys/image_79a4/foregroundimg.img.320.high.jpg/1694120178313.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4672/itemParsys/image_79a4/foregroundimg.img.480.high.jpg/1694120178313.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4672/itemParsys/image_79a4/foregroundimg.img.320.medium.jpg/1694120178313.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4672/itemParsys/image_79a4/foregroundimg.img.620.high.jpg/1694120178313.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4672/itemParsys/image_79a4/foregroundimg.img.320.low.jpg/1694120178313.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4672/itemParsys/image_79a4/foregroundimg.img.480.medium.jpg/1694120178313.jpg" alt='SMART Digest vs. Conventional In-Solution Digest Protocol' title='SMART Digest vs. Conventional In-Solution Digest Protocol'></picture><style> #cq-image-jsp-66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_4672itemParsysimage_79a4 img{ width:100%; max-width: 690px; } </style><script type="text/javascript"> $( document ).ready(function() { // apply fillIt plugin var fillClasses = "#cq-image-jsp-"+"66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_4672itemParsysimage_79a4 .image-contain" + "," + "#cq-image-jsp-"+"66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_4672itemParsysimage_79a4 .image-cover" ; // Due to the issue explained below, we are binding 'one' instead of 'on' and we need it only once. $(fillClasses).load(function() { $(this).fillIt(); }); // Force load image to avoid cache issue, a bug which makes image reset height when having more than one image/image-text components on the same page and rendering after edit. $(fillClasses).each(function(){ if(this.complete){ $(this).load(); } }); if(!!window.picturefill){ window.picturefill(); } }); </script></div></div><div class="text parbase section"><div class="table-component-wrapper"><table class="rte-table" id="table-758464644"><tbody><tr><th colspan="4" style="text-align: center;">Typical SMART Digest Digestion Times</th></tr><tr><th style="text-align: center;">Protein</th><th style="text-align: center;">Digestion Time</th><th style="text-align: center;">Protein</th><th style="text-align: center;">Digestion Time</th></tr><tr><td>Insulin</td><td>4 min</td><td>IgG in 50 µL plasma*</td><td>75 min</td></tr><tr><td>BSA</td><td>< 5 min</td><td>Ribonuclease A</td><td>150 min</td></tr><tr><td>Carbonic anhydrase</td><td>< 5 min</td><td>Thyroglobulin</td><td>240 min</td></tr><tr><td>Lysozyme</td><td>< 5 min</td><td>C-reactive protein</td><td>240 min</td></tr><tr><td>Apo-B 30 IgG</td><td>45 min</td><td> </td><td> </td><td> </td></tr></tbody></table></div><p><small><i>200μL protein solution (100 μg/mL) at 70 °C</i><br><i>* IgG in plasma (17.5mg/mL total protein) at 70 °C</i></small></p></div><div class="well-cmp well-default well-blue-light section"><div class="well well-blue-light well-default"><div class="well-container" style=""><div class="well-content"><div class="parsys"><div comp-order="bycol" class="parsys_column cq-colctrl-lt0"><div class="parsys_column cq-colctrl-lt0-c0"><div container-id="cq-colctrl-lt0" comp-id="A1"><div class="image parbase section"><div id="cq-image-jsp-66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_4672itemParsyswell_a1c8uiparimage_b78c"><a href="http://info1.thermoscientific.com/peptidemapping?icid=L4-PM-SPB_01-CMD-WB41462-PB_EMB_PMHYP-20170711-EMEA#&page=calculator" target='_blank'><picture><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4672/itemParsys/well_a1c8/uipar/image_b78c/foregroundimg.img.320.medium.jpg/1694120178378.jpg' media="(min-width: 1px)"><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4672/itemParsys/well_a1c8/uipar/image_b78c/foregroundimg.img.480.high.jpg/1694120178378.jpg' media="(min-width: 490px)"><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4672/itemParsys/well_a1c8/uipar/image_b78c/foregroundimg.img.620.high.jpg/1694120178378.jpg' media="(min-width: 630px)"><img srcset="https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4672/itemParsys/well_a1c8/uipar/image_b78c/foregroundimg.img.full.high.jpg/1694120178378.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4672/itemParsys/well_a1c8/uipar/image_b78c/foregroundimg.img.320.high.jpg/1694120178378.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4672/itemParsys/well_a1c8/uipar/image_b78c/foregroundimg.img.480.high.jpg/1694120178378.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4672/itemParsys/well_a1c8/uipar/image_b78c/foregroundimg.img.320.medium.jpg/1694120178378.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4672/itemParsys/well_a1c8/uipar/image_b78c/foregroundimg.img.620.high.jpg/1694120178378.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4672/itemParsys/well_a1c8/uipar/image_b78c/foregroundimg.img.320.low.jpg/1694120178378.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_4672/itemParsys/well_a1c8/uipar/image_b78c/foregroundimg.img.480.medium.jpg/1694120178378.jpg" alt='Calculate how much time you will save' title='Calculate how much time you will save'></picture><style> #cq-image-jsp-66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_4672itemParsyswell_a1c8uiparimage_b78c img{ width:100%; max-width: 635px; } </style><script type="text/javascript"> $( document ).ready(function() { // apply fillIt plugin var fillClasses = "#cq-image-jsp-"+"66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_4672itemParsyswell_a1c8uiparimage_b78c .image-contain" + "," + "#cq-image-jsp-"+"66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_4672itemParsyswell_a1c8uiparimage_b78c .image-cover" ; // Due to the issue explained below, we are binding 'one' instead of 'on' and we need it only once. $(fillClasses).load(function() { $(this).fillIt(); }); // Force load image to avoid cache issue, a bug which makes image reset height when having more than one image/image-text components on the same page and rendering after edit. $(fillClasses).each(function(){ if(this.complete){ $(this).load(); } }); if(!!window.picturefill){ window.picturefill(); } }); </script></a></div></div></div></div><div class="parsys_column cq-colctrl-lt0-c1"><div container-id="cq-colctrl-lt0" comp-id="B1"><div class="heading section"><h3> Calculate how much time you will save </h3></div></div><div container-id="cq-colctrl-lt0" comp-id="B2"><div class="text parbase section"><p>Just select the size of your protein to see how much time you will save using SMART Digest kits.</p><ul class="the-icons clearfix"><li><span class="icon icon-outbound"></span><a href="http://info1.thermoscientific.com/peptidemapping?icid=L4-PM-SPB_01-CMD-WB41462-PB_EMB_PMHYP-20170711-EMEA#&page=calculator" target="_blank">Calculate time savings now</a></li></ul></div></div></div></div><div style="clear:both"></div></div></div></div></div></div><div class="text parbase section"><ul class="the-icons clearfix"><li><span class="icon-lt-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/AN-1159-SP-SMART-Digest-Peptides-AN72141-EN.pdf" target="_blank">SMART Digest compared to classic in-solution digestion of rituximab for in-depth peptide mapping characterization</a></li></ul></div></div></div></div></div></div></div><div class="accordionitem section"><div class='accordion-group' ><div class='accordion-heading '><a class="accordion-toggle" data-toggle="collapse" data-parent="#da4342d29e1f495fa0f58de85d5e6d44" href="#improvereproducibility"><span class="caret"></span> Improve reproducibility </a></div><div class="accordion-body collapse " id="improvereproducibility"><div class="accordion-inner"><div class="accordion-content"><div class="itemParsys parsys"><div class="heading section"><h2> Improve reproducibility </h2></div><div class="text parbase section"><p>The chromatogram overlay below is from three separate SMART digestions from the same mAb, conducted by three individual operators. The 15 marked peptides in each sample were used for inter-user/inter-day RSD value calculations.</p></div><div class="image parbase section"><div id="cq-image-jsp-66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_6842itemParsysimage_b62d"><a class="image-enlarge-link" data-lightbox="image_b62d" href="/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/_jcr_content/MainParsys/accordion_7b4d/itemspar/accordionitem_6842/itemParsys/image_b62d/backgroundimg.img.jpg/1694120178481.jpg"><picture><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_6842/itemParsys/image_b62d/foregroundimg.img.320.medium.jpg/1694120178466.jpg' media="(min-width: 1px)"><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_6842/itemParsys/image_b62d/foregroundimg.img.480.high.jpg/1694120178466.jpg' media="(min-width: 490px)"><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_6842/itemParsys/image_b62d/foregroundimg.img.620.high.jpg/1694120178466.jpg' media="(min-width: 630px)"><img srcset="https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_6842/itemParsys/image_b62d/foregroundimg.img.full.high.jpg/1694120178466.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_6842/itemParsys/image_b62d/foregroundimg.img.320.high.jpg/1694120178466.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_6842/itemParsys/image_b62d/foregroundimg.img.480.high.jpg/1694120178466.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_6842/itemParsys/image_b62d/foregroundimg.img.320.medium.jpg/1694120178466.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_6842/itemParsys/image_b62d/foregroundimg.img.620.high.jpg/1694120178466.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_6842/itemParsys/image_b62d/foregroundimg.img.320.low.jpg/1694120178466.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_6842/itemParsys/image_b62d/foregroundimg.img.480.medium.jpg/1694120178466.jpg" alt='UV chromatogram overlay from three separate SMART digestions from the same mAb, conducted by three individual operators.' title='UV chromatogram overlay from three separate SMART digestions from the same mAb, conducted by three individual operators.'></picture><style> #cq-image-jsp-66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_6842itemParsysimage_b62d img{ width:100%; max-width: 740px; } </style><script type="text/javascript"> $( document ).ready(function() { // apply fillIt plugin var fillClasses = "#cq-image-jsp-"+"66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_6842itemParsysimage_b62d .image-contain" + "," + "#cq-image-jsp-"+"66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_6842itemParsysimage_b62d .image-cover" ; // Due to the issue explained below, we are binding 'one' instead of 'on' and we need it only once. $(fillClasses).load(function() { $(this).fillIt(); }); // Force load image to avoid cache issue, a bug which makes image reset height when having more than one image/image-text components on the same page and rendering after edit. $(fillClasses).each(function(){ if(this.complete){ $(this).load(); } }); if(!!window.picturefill){ window.picturefill(); } }); </script></a><div class="caption"><small><b>UV chromatogram overlay from three separate SMART digestions from the same mAb, conducted by three individual operators.</b> The 15 marked peptides in each sample were used for inter-user/inter-day RSD value calculations. <small><span class="icon-zoom-in"></span> Click image to enlarge</small></small></div></div></div><div class="text parbase section"><ul class="the-icons clearfix"><li><span class="icon-lt-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/AN-1159-SP-SMART-Digest-Peptides-AN72141-EN.pdf" target="_blank">Digestion of rituximab for in-depth peptide mapping characterization</a></li></ul></div></div></div></div></div></div></div><div class="accordionitem section"><div class='accordion-group' ><div class='accordion-heading '><a class="accordion-toggle" data-toggle="collapse" data-parent="#da4342d29e1f495fa0f58de85d5e6d44" href="#automatedigestion"><span class="caret"></span> Automate protein digestion for peptide mapping and quantitation </a></div><div class="accordion-body collapse " id="automatedigestion"><div class="accordion-inner"><div class="accordion-content"><div class="itemParsys parsys"><div class="heading section"><h2> Automate protein digestion for peptide mapping and quantitation </h2></div><div class="text parbase section"><p>Peptide mapping and quantitation are fundamental workflows used in the development of biotherapeutics to ensure structural integrity, drug efficacy and patient safety. Current sample preparation techniques are complex, laborious, prone to error, and not amenable to automation impacting reanalysis rates, transfer, and implementation of methods at different sites. </p><p>SMART Digest protein digestion provides a simple process on magnetic bead technology which allows it to be automated on platforms like the  Thermo Scientific King Fisher Duo to enable easy, fast, and highly reproducible results.</p></div><div class="heading section"><h3> Peptide mapping workflow </h3></div><div class="image parbase section"><div id="cq-image-jsp-66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_f901itemParsysimage_554b"><picture><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_554b/foregroundimg.img.320.low.jpg/1694120178573.jpg' media="(min-width: 1px)"><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_554b/foregroundimg.img.320.medium.jpg/1694120178573.jpg' media="(min-width: 320px)"><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_554b/foregroundimg.img.480.medium.jpg/1694120178573.jpg' media="(min-width: 490px)"><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_554b/foregroundimg.img.620.high.jpg/1694120178573.jpg' media="(min-width: 630px)"><img srcset="https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_554b/foregroundimg.img.full.high.jpg/1694120178573.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_554b/foregroundimg.img.320.high.jpg/1694120178573.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_554b/foregroundimg.img.480.high.jpg/1694120178573.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_554b/foregroundimg.img.320.medium.jpg/1694120178573.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_554b/foregroundimg.img.620.high.jpg/1694120178573.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_554b/foregroundimg.img.320.low.jpg/1694120178573.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_554b/foregroundimg.img.480.medium.jpg/1694120178573.jpg" alt='Peptide mapping workflow' title='Peptide mapping workflow'></picture><style> #cq-image-jsp-66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_f901itemParsysimage_554b img{ width:100%; max-width: 881px; } </style><script type="text/javascript"> $( document ).ready(function() { // apply fillIt plugin var fillClasses = "#cq-image-jsp-"+"66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_f901itemParsysimage_554b .image-contain" + "," + "#cq-image-jsp-"+"66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_f901itemParsysimage_554b .image-cover" ; // Due to the issue explained below, we are binding 'one' instead of 'on' and we need it only once. $(fillClasses).load(function() { $(this).fillIt(); }); // Force load image to avoid cache issue, a bug which makes image reset height when having more than one image/image-text components on the same page and rendering after edit. $(fillClasses).each(function(){ if(this.complete){ $(this).load(); } }); if(!!window.picturefill){ window.picturefill(); } }); </script></div></div><div class="heading section"><h3> Peptide quantitation workflow </h3></div><div class="image parbase section"><div id="cq-image-jsp-66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_f901itemParsysimage_e2c0"><picture><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_e2c0/foregroundimg.img.320.low.jpg/1694120178601.jpg' media="(min-width: 1px)"><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_e2c0/foregroundimg.img.320.medium.jpg/1694120178601.jpg' media="(min-width: 320px)"><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_e2c0/foregroundimg.img.480.medium.jpg/1694120178601.jpg' media="(min-width: 490px)"><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_e2c0/foregroundimg.img.620.high.jpg/1694120178601.jpg' media="(min-width: 630px)"><img srcset="https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_e2c0/foregroundimg.img.full.high.jpg/1694120178601.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_e2c0/foregroundimg.img.320.high.jpg/1694120178601.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_e2c0/foregroundimg.img.480.high.jpg/1694120178601.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_e2c0/foregroundimg.img.320.medium.jpg/1694120178601.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_e2c0/foregroundimg.img.620.high.jpg/1694120178601.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_e2c0/foregroundimg.img.320.low.jpg/1694120178601.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_e2c0/foregroundimg.img.480.medium.jpg/1694120178601.jpg" alt='Peptide quantitation workflow' title='Peptide quantitation workflow'></picture><style> #cq-image-jsp-66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_f901itemParsysimage_e2c0 img{ width:100%; max-width: 881px; } </style><script type="text/javascript"> $( document ).ready(function() { // apply fillIt plugin var fillClasses = "#cq-image-jsp-"+"66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_f901itemParsysimage_e2c0 .image-contain" + "," + "#cq-image-jsp-"+"66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_f901itemParsysimage_e2c0 .image-cover" ; // Due to the issue explained below, we are binding 'one' instead of 'on' and we need it only once. $(fillClasses).load(function() { $(this).fillIt(); }); // Force load image to avoid cache issue, a bug which makes image reset height when having more than one image/image-text components on the same page and rendering after edit. $(fillClasses).each(function(){ if(this.complete){ $(this).load(); } }); if(!!window.picturefill){ window.picturefill(); } }); </script></div></div><div comp-order="bycol" class="parsys_column cq-colctrl-lt8"><div class="parsys_column cq-colctrl-lt8-c0"><div container-id="cq-colctrl-lt8" comp-id="A1"><div class="image parbase section"><div id="cq-image-jsp-66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_f901itemParsysimage_e71c"><a href="/sg/en/home/global/forms/industrial/peptide-mapping-multi-attribute-monitoring.html"><picture><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_e71c/foregroundimg.img.320.high.jpg/1694120178626.jpg' media="(min-width: 1px)"><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_e71c/foregroundimg.img.480.high.jpg/1694120178626.jpg' media="(min-width: 490px)"><img srcset="https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_e71c/foregroundimg.img.full.high.jpg/1694120178626.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_e71c/foregroundimg.img.320.high.jpg/1694120178626.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_e71c/foregroundimg.img.480.high.jpg/1694120178626.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_e71c/foregroundimg.img.320.medium.jpg/1694120178626.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_e71c/foregroundimg.img.620.high.jpg/1694120178626.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_e71c/foregroundimg.img.320.low.jpg/1694120178626.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_e71c/foregroundimg.img.480.medium.jpg/1694120178626.jpg" alt='Rapid, Automated Peptide Mapping for Multi Attribute Monitoring' title='Rapid, Automated Peptide Mapping for Multi Attribute Monitoring'></picture><style> #cq-image-jsp-66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_f901itemParsysimage_e71c img{ width:100%; max-width: 550px; } </style><script type="text/javascript"> $( document ).ready(function() { // apply fillIt plugin var fillClasses = "#cq-image-jsp-"+"66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_f901itemParsysimage_e71c .image-contain" + "," + "#cq-image-jsp-"+"66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_f901itemParsysimage_e71c .image-cover" ; // Due to the issue explained below, we are binding 'one' instead of 'on' and we need it only once. $(fillClasses).load(function() { $(this).fillIt(); }); // Force load image to avoid cache issue, a bug which makes image reset height when having more than one image/image-text components on the same page and rendering after edit. $(fillClasses).each(function(){ if(this.complete){ $(this).load(); } }); if(!!window.picturefill){ window.picturefill(); } }); </script></a></div></div></div></div><div class="parsys_column cq-colctrl-lt8-c1"><div container-id="cq-colctrl-lt8" comp-id="B1"><div class="text parbase section"><h3>Rapid Automated Peptide Mapping for Multi-Attribute Monitoring webinar</h3><p>Dr. Ken Cook (Thermo Fisher Scientific) and Dr. Sara Carillo (National Institute for Bioprocessing Research and Training -NIBRT) discuss:</p><ul><li>Challenges in peptide mapping and sample preparation</li><li>New technologies that overcome peptide mapping issues</li><li>How new automated technologies compare to existing practices</li></ul><p><a href="/sg/en/home/global/forms/industrial/peptide-mapping-multi-attribute-monitoring.html">Attend Rapid Automated Peptide Mapping webinar</a></p></div></div></div></div><div style="clear:both"></div><div comp-order="bycol" class="parsys_column cq-colctrl-lt8"><div class="parsys_column cq-colctrl-lt8-c0"><div container-id="cq-colctrl-lt8" comp-id="A1"><div class="image parbase section"><div id="cq-image-jsp-66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_f901itemParsysimage_b1e6"><a href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/AN-21682-SP-LC-MS-Peptide-Mapping-Proteins-AN21682-EN.pdf" target='_blank'><picture><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_b1e6/foregroundimg.img.full.high.jpg/1694120178667.jpg' media="(min-width: 1px)"><img srcset="https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_b1e6/foregroundimg.img.full.high.jpg/1694120178667.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_b1e6/foregroundimg.img.320.high.jpg/1694120178667.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_b1e6/foregroundimg.img.480.high.jpg/1694120178667.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_b1e6/foregroundimg.img.320.medium.jpg/1694120178667.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_b1e6/foregroundimg.img.620.high.jpg/1694120178667.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_b1e6/foregroundimg.img.320.low.jpg/1694120178667.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/accordion_7b4d/itemspar/accordionitem_f901/itemParsys/image_b1e6/foregroundimg.img.480.medium.jpg/1694120178667.jpg" alt='Application Note: High Precision, Automated Peptide Mapping of Proteins' title='Application Note: High Precision, Automated Peptide Mapping of Proteins'></picture><style> #cq-image-jsp-66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_f901itemParsysimage_b1e6 img{ width:100%; max-width: 270px; } </style><script type="text/javascript"> $( document ).ready(function() { // apply fillIt plugin var fillClasses = "#cq-image-jsp-"+"66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_f901itemParsysimage_b1e6 .image-contain" + "," + "#cq-image-jsp-"+"66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysaccordion_7b4ditemsparaccordionitem_f901itemParsysimage_b1e6 .image-cover" ; // Due to the issue explained below, we are binding 'one' instead of 'on' and we need it only once. $(fillClasses).load(function() { $(this).fillIt(); }); // Force load image to avoid cache issue, a bug which makes image reset height when having more than one image/image-text components on the same page and rendering after edit. $(fillClasses).each(function(){ if(this.complete){ $(this).load(); } }); if(!!window.picturefill){ window.picturefill(); } }); </script></a></div></div></div></div><div class="parsys_column cq-colctrl-lt8-c1"><div container-id="cq-colctrl-lt8" comp-id="B1"><div class="text parbase section"><h3>Application Note: High Precision, Automated Peptide Mapping of Proteins</h3><ul><li>Details automated peptide mapping of cytochrome c, recombinant somatotropin, and infliximab drug product.</li><li>Employs SMART Digest magnetic beads and the KingFisher Duo purification system</li><li>Demonstrates applicability and reproducibility of the automated digestion protocol and subsequent analysis.</li><li>Produces high quality, reproducible peptide mapping data.</li></ul><ul class="the-icons clearfix"><li><span class="icon-lt-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/AN-21682-SP-LC-MS-Peptide-Mapping-Proteins-AN21682-EN.pdf" target="_blank">Application Note: Automated Peptide Mapping</a></li></ul></div></div></div></div><div style="clear:both"></div><div class="well-cmp well-default well-blue-light section"><div class="well well-blue-light well-default"><div class="well-container" style=""><div class="well-content"><div class="parsys"><div class="heading section"><h4> Learn more </h4></div><div class="text parbase section"><ul class="the-icons clearfix"><li><span class="icon-lt-pdf"></span>Application note: <a target="_blank" href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/an-21835-lc-ms-peptide-mapping-ptm-mab-an21835-en.pdf">An automated high-throughput workflow for peptide mapping to monitor post-translational modifications (PTMs) of monoclonal antibodies</a></li><li><span class="icon-lt-pdf"></span>Application note: <a target="_blank" href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/an-21834-lc-ms-chymotrypsin-peptide-mapping-an21834-en.pdf">Automated chymotrypsin peptide mapping of proteins by LC-MS</a></li><li><span class="icon-lt-pdf"></span>Application note: <a target="_blank" href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/an-21782-lc-ms-peptide-map-digest-comparison-an21782-en.pdf">Comparison of alternative approaches to trypsin protein digestion for reproducible and efficient peptide mapping analysis of monoclonal antibodies</a></li><li><span class="icon-lt-pdf"></span>Application note: <a target="_blank" href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/AN-21682-SP-LC-MS-Peptide-Mapping-Proteins-AN21682-EN.pdf">High-precision, automated peptide mapping of proteins</a></li><li><span class="icon-lt-pdf"></span>Application note: <a target="_blank" href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/an-21918-lc-ms-monoclonal-antibody-preparations-an21918-en.pdf">Easy, fast and reproducible analysis of host cell protein (HCP) in monoclonal antibody preparations</a></li></ul></div></div></div></div></div></div></div></div></div></div></div></div></div></div><script> $j(document).ready(function(){ $j('#da4342d29e1f495fa0f58de85d5e6d44').on('hide', function(e) { $(e.target).find(".accordion-content").hide(); }); $j('#da4342d29e1f495fa0f58de85d5e6d44').on('show', function(e) { $(e.target).find(".accordion-content").show(); }); }); </script></div><div class="divider section"><hr /></div><div class="heading section"><h2> SMART Digest webinars </h2></div><div comp-order="bycol" class="parsys_column cq-colctrl-lt8"><div class="parsys_column cq-colctrl-lt8-c0"><div container-id="cq-colctrl-lt8" comp-id="A1"><div class="image parbase section"><div id="cq-image-jsp-66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysimage_931d"><picture><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/image_931d/foregroundimg.img.full.high.jpg/1694120178748.jpg' media="(min-width: 1px)"><img srcset="https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/image_931d/foregroundimg.img.full.high.jpg/1694120178748.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/image_931d/foregroundimg.img.320.high.jpg/1694120178748.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/image_931d/foregroundimg.img.480.high.jpg/1694120178748.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/image_931d/foregroundimg.img.320.medium.jpg/1694120178748.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/image_931d/foregroundimg.img.620.high.jpg/1694120178748.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/image_931d/foregroundimg.img.320.low.jpg/1694120178748.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/image_931d/foregroundimg.img.480.medium.jpg/1694120178748.jpg" alt='SMART Digest webinar series' title='SMART Digest webinar series'></picture><style> #cq-image-jsp-66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysimage_931d img{ width:100%; max-width: 270px; } </style><script type="text/javascript"> $( document ).ready(function() { // apply fillIt plugin var fillClasses = "#cq-image-jsp-"+"66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysimage_931d .image-contain" + "," + "#cq-image-jsp-"+"66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysimage_931d .image-cover" ; // Due to the issue explained below, we are binding 'one' instead of 'on' and we need it only once. $(fillClasses).load(function() { $(this).fillIt(); }); // Force load image to avoid cache issue, a bug which makes image reset height when having more than one image/image-text components on the same page and rendering after edit. $(fillClasses).each(function(){ if(this.complete){ $(this).load(); } }); if(!!window.picturefill){ window.picturefill(); } }); </script></div></div></div></div><div class="parsys_column cq-colctrl-lt8-c1"><div container-id="cq-colctrl-lt8" comp-id="B1"><div class="text parbase section"><h3>SMART Digest webinar series</h3><p>Learn about four new technologies that dramatically improve peptide mapping workflows and increases confidence. </p><ul><li>Webinar 1: Don’t Miss a Thing on Your Peptide Mapping Journey</li><li>Webinar 2: Take the Smart Route to Protein Digestion</li><li>Webinar 3: Technologies for Improved Peptide Quantitation Workflow</li><li>Webinar 4: Peptide Separations with Pinpoint Precision</li></ul><p><a href="/sg/en/home/global/forms/industrial/smart-digest-webinars.html">Attend Protein Digestion Webinar Series</a></p></div></div></div></div><div style="clear:both"></div><div comp-order="bycol" class="parsys_column cq-colctrl-lt8"><div class="parsys_column cq-colctrl-lt8-c0"><div container-id="cq-colctrl-lt8" comp-id="A1"><div class="image parbase section"><div id="cq-image-jsp-66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysimage_cdf0"><a href="/sg/en/home/global/forms/industrial/peptide-mapping-multi-attribute-monitoring.html"><picture><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/image_cdf0/foregroundimg.img.320.high.jpg/1694120178782.jpg' media="(min-width: 1px)"><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/image_cdf0/foregroundimg.img.480.high.jpg/1694120178782.jpg' media="(min-width: 490px)"><img srcset="https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/image_cdf0/foregroundimg.img.full.high.jpg/1694120178782.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/image_cdf0/foregroundimg.img.320.high.jpg/1694120178782.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/image_cdf0/foregroundimg.img.480.high.jpg/1694120178782.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/image_cdf0/foregroundimg.img.320.medium.jpg/1694120178782.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/image_cdf0/foregroundimg.img.620.high.jpg/1694120178782.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/image_cdf0/foregroundimg.img.320.low.jpg/1694120178782.jpg,https://www.thermofisher.com/sg/en/home/industrial/chromatography/chromatography-sample-preparation/sample-preparation-consumables/protein-digest/jcr:content/MainParsys/image_cdf0/foregroundimg.img.480.medium.jpg/1694120178782.jpg" alt='Rapid, Automated Peptide Mapping for Multi Attribute Monitoring' title='Rapid, Automated Peptide Mapping for Multi Attribute Monitoring'></picture><style> #cq-image-jsp-66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysimage_cdf0 img{ width:100%; max-width: 550px; } </style><script type="text/javascript"> $( document ).ready(function() { // apply fillIt plugin var fillClasses = "#cq-image-jsp-"+"66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysimage_cdf0 .image-contain" + "," + "#cq-image-jsp-"+"66a4f7c1-31e6-49ac-a759-55a78444c173MainParsysimage_cdf0 .image-cover" ; // Due to the issue explained below, we are binding 'one' instead of 'on' and we need it only once. $(fillClasses).load(function() { $(this).fillIt(); }); // Force load image to avoid cache issue, a bug which makes image reset height when having more than one image/image-text components on the same page and rendering after edit. $(fillClasses).each(function(){ if(this.complete){ $(this).load(); } }); if(!!window.picturefill){ window.picturefill(); } }); </script></a></div></div></div></div><div class="parsys_column cq-colctrl-lt8-c1"><div container-id="cq-colctrl-lt8" comp-id="B1"><div class="text parbase section"><h3>Rapid Automated Peptide Mapping for Multi-Attribute Monitoring webinar</h3><p>Dr. Ken Cook (Thermo Fisher Scientific) and Dr. Sara Carillo (National Institute for Bioprocessing Research and Training -NIBRT) discuss: </p><ul><li>Challenges in peptide mapping and sample preparation</li><li>New technologies that overcome peptide mapping issues </li><li>How new automated technologies compare to existing practices</li></ul><p><a href="/sg/en/home/global/forms/industrial/peptide-mapping-multi-attribute-monitoring.html">Attend Rapid Automated Peptide Mapping webinar</a></p></div></div></div></div><div style="clear:both"></div><div class="divider section"><hr /></div><div class="heading section"><h2 id="video"> SMART Digest videos </h2></div><div comp-order="bycol" class="parsys_column cq-colctrl-lt0"><div class="parsys_column cq-colctrl-lt0-c0"><div container-id="cq-colctrl-lt0" comp-id="A1"><div class="brightcoveplayer section"><div data-video="27410e467f62"><script type="text/javascript"> var loadEME = true; 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Our enhanced online version features easier access to product information, key application notes and brand-new selector tools.</p><p><a href="/sg/en/home/global/forms/industrial/consumables-catalogue.html"><span class="btn btn-primary">Get the Sample Preparation catalog</span></a></p></div></div></div></div><div style="clear:both"></div></div></div></div></div></div></div></div><div class="divider section"><hr /></div><div class="reference parbase section"><div class="cq-dd-paragraph"><div class="well-cmp"><div class="well "><div class="well-container" style=""><div class="well-content"><div class="parsys"><div comp-order="bycol" class="parsys_column cq-colctrl-lt8"><div class="parsys_column cq-colctrl-lt8-c0"><div container-id="cq-colctrl-lt8" comp-id="A1"><div class="image parbase section"><div id="cq-image-jsp-8c1eb867-add2-4d59-af62-4c53e1dc9c33MainParsyswell_e8d7uiparimage_c526"><a 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if(!!window.picturefill){ window.picturefill(); } }); </script></a></div></div></div></div><div class="parsys_column cq-colctrl-lt8-c1"><div container-id="cq-colctrl-lt8" comp-id="B1"><div class="text parbase section"><div class="h3"> Chromatography Consumables Resources and Information </div><p>Find interactive tools and calculators, guides to select the right products, equivalent product finders, and get in contact with our consumables technical support team to answer your application questions.</p><p><a href="/sg/en/home/industrial/chromatography/chromatography-learning-center/chromatography-consumables-resources.html"><span class="btn btn-primary">Discover more resources </span></a></p></div></div></div></div><div style="clear:both"></div></div></div></div></div></div></div></div><div class="reference parbase section"><div class="cq-dd-paragraph"><div class="well-cmp well-default well-blue-light"><div class="well well-blue-light well-default"><div class="well-container" style=""><div class="well-content"><div class="parsys"><div comp-order="bycol" class="parsys_column cq-colctrl-lt8"><div class="parsys_column cq-colctrl-lt8-c0"><div container-id="cq-colctrl-lt8" comp-id="A1"><div class="image parbase section"><div id="cq-image-jsp-8b39c402-f0ff-4a9b-a539-7bd4aa5ecb50MainParsyswell_7bb4uiparimage_1fb3"><a href="/sg/en/home/about-us/events/industrial/analytical-innovations-webinars.html"><picture><source srcset='https://www.thermofisher.com/sg/en/home/industrial/chromatography/liquid-chromatography-lc/hplc-uhplc-columns/bio-lc-columns/protein-hplc-columns/jcr:content/MainParsys/well_7bb4/uipar/image_1fb3.img.full.high.jpg/1664387081659.jpg' media="(min-width: 1px)"><img 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alt='Chromatography consumables on-demand webinar series' title='Chromatography consumables on-demand webinar series'></picture><style> #cq-image-jsp-8b39c402-f0ff-4a9b-a539-7bd4aa5ecb50MainParsyswell_7bb4uiparimage_1fb3 img{ width:100%; max-width: 270px; } </style><script type="text/javascript"> $( document ).ready(function() { if(!!window.picturefill){ window.picturefill(); } }); </script></a></div></div></div></div><div class="parsys_column cq-colctrl-lt8-c1"><div container-id="cq-colctrl-lt8" comp-id="B1"><div class="heading section"><h3><a href="/sg/en/home/about-us/events/industrial/analytical-innovations-webinars.html">Chromatography consumables on-demand webinar series</a></h3></div></div><div container-id="cq-colctrl-lt8" comp-id="B2"><div class="text parbase section"><p>Discover live and on-demand webinars that enable you to improve productivity, maintain compliance, and learn about the constantly evolving scientific landscape.</p><p><a href="/sg/en/home/about-us/events/industrial/analytical-innovations-webinars.html"><span class="btn btn-primary">Watch now</span></a></p></div></div></div></div><div style="clear:both"></div></div></div></div></div></div></div></div><div class="well-cmp well-default well-gray-lighter section"><div class="well well-gray-lighter well-default"><div class="well-container" style=""><div class="well-content"><div class="parsys"><div class="heading section"><div class="h2"> Resources </div></div><div comp-order="bycol" class="parsys_column cq-colctrl-lt0"><div class="parsys_column cq-colctrl-lt0-c0"><div container-id="cq-colctrl-lt0" comp-id="A1"><div class="accordion section"><div class="accordion" id="1dcedbe99cc0415a86936a0a02f59155" style='margin-bottom: 0;'><div class="parsys"><div class="accordionitem section"><div class='accordion-group' ><div class='accordion-heading '><a class="accordion-toggle" data-toggle="collapse" data-parent="#1dcedbe99cc0415a86936a0a02f59155" href="#webinars"><span class="caret"></span> Webinars </a></div><div class="accordion-body collapse " id="webinars"><div class="accordion-inner"><div class="accordion-content"><div class="itemParsys parsys"><div class="heading section"><h4> Webinars </h4></div><div class="text parbase section"><ul class="the-icons clearfix"><li><a href="/sg/en/home/global/forms/industrial/smart-digest-webinars.html">SMART Digest webinar series</a></li><li><a href="/sg/en/home/global/forms/industrial/peptide-mapping-multi-attribute-monitoring.html">Rapid Automated Peptide Mapping for Multi-Attribute Monitoring webinar</a></li></ul></div></div></div></div></div></div></div><div class="accordionitem section"><div class='accordion-group' ><div class='accordion-heading '><a class="accordion-toggle" data-toggle="collapse" data-parent="#1dcedbe99cc0415a86936a0a02f59155" href="#appnotecompendium"><span class="caret"></span> Application Note Compendium </a></div><div class="accordion-body collapse " id="appnotecompendium"><div class="accordion-inner"><div class="accordion-content"><div class="itemParsys parsys"><div class="heading section"><h4> Compendium </h4></div><div class="text parbase section"><ul class="the-icons clearfix"><li><span class="icon-lt-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/an-21878-smart-digest-compendium-an21878-en.pdf" target="_blank">SMART Digest Peptide Mapping and Quantitation Compendium</a></li></ul></div></div></div></div></div></div></div><div class="accordionitem section"><div class='accordion-group' ><div class='accordion-heading '><a class="accordion-toggle" data-toggle="collapse" data-parent="#1dcedbe99cc0415a86936a0a02f59155" href="#productliterature"><span class="caret"></span> Product Literature </a></div><div class="accordion-body collapse " id="productliterature"><div class="accordion-inner"><div class="accordion-content"><div class="itemParsys parsys"><div class="heading section"><h4> Product literature </h4></div><div class="text parbase section"><ul class="the-icons clearfix"><li><span class="icon-lt-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/CMD/Technical-Notes/tn-21649-peptide-recovery-tn21649-en.pdf">Technical Note: Recovery Study of Peptides from Different 96-Well Collection Plates</a></li><li><span class="icon-lt-pdf"></span><a target="_blank" href="https://assets.thermofisher.com/TFS-Assets/CMD/brochures/TG-21544-SMART-Digest-IA-TG21544-EN.pdf">Technical Guide: SMART Digest and SMART Digest ImmunoAffinity (IA) Kit</a></li><li><span class="icon-lt-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/CMD/brochures/BR-72040-Peptide-Mapping-Workflows-BR72040-EN.pdf">Brochure: Upgrade Your Peptide Mapping Workflows</a></li><li><span class="icon-lt-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/BID/brochures/kingfisher-instruments-experience-brochure.pdf">Brochure: Automated Sample Preparation for DNA, RNA, Protein, or Cells</a></li><li><span class="icon-lt-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/AN-21682-SP-LC-MS-Peptide-Mapping-Proteins-AN21682-EN.pdf">Brochure: High-precision, Automated Peptide Mapping of Proteins</a></li><li><span class="icon-lt-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/CMD/brochures/br-22105-protein-digestion-peptide-mapping-quantitation-br22105-en.pdf">Brochure: Protein Digestion for Peptide Mapping and Quantitation: Overview of SMART Digest and SMART Digest ImmunoAffinity Kits</a></li><li><span class="icon-lt-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/CMD/brochures/br-001229-ccs-LC-columns-mRNA-charge-variance-br001229-na-en.pdf">Brochure: Chromatography columns and consumables - BioPharma workflow solutions</a></li><li><span class="icon-lt-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/CMD/brochures/br-001176-ccs-nano-low-flow-columns-proteomics-br001176-na-en.pdf">Brochure: Chromatography columns and consumables - Proteomics workflow solutions</a></li><li><span class="icon-lt-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/CMD/brochures/br-001226-ccs-LC-columns-drugs-of-abuse-vitamin-D-br001226-na-en.pdf">Brochure: Chromatography columns and consumables - Clinical workflow solutions</a></li></ul></div></div></div></div></div></div></div><div class="accordionitem section"><div class='accordion-group' ><div class='accordion-heading '><a class="accordion-toggle" data-toggle="collapse" data-parent="#1dcedbe99cc0415a86936a0a02f59155" href="#appnotes"><span class="caret"></span> Application Notes </a></div><div class="accordion-body collapse " id="appnotes"><div class="accordion-inner"><div class="accordion-content"><div class="itemParsys parsys"><div class="heading section"><h4> Application notes </h4></div><div class="text parbase section"><ul class="the-icons clearfix"><li><span class="icon-lt-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/can-73826-lc-ms-peptide-mapping-of-challenging-mabs-can73826-en.pdf" target="_blank">Peptide Mapping of Challenging Monoclonal Antibodies</a></li><li><span class="icon-lt-pdf"></span><a target="_blank" href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/an-21835-lc-ms-peptide-mapping-ptm-mab-an21835-en.pdf">An Automated High-Throughput Workflow for Peptide Mapping to Monitor Post-Translational Modifications (PTMs) of mAbs</a></li><li><span class="icon-lt-pdf"></span><a target="_blank" href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/an-21834-lc-ms-chymotrypsin-peptide-mapping-an21834-en.pdf">Automated Chymotrypsin Peptide Mapping of Proteins by LC-MS</a></li><li><span class="icon-lt-pdf"></span><a target="_blank" href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/an-21782-lc-ms-peptide-map-digest-comparison-an21782-en.pdf">Comparison of Alternative Approaches to Trypsin Protein Digestion for Reproducible and Efficient Peptide Mapping Analysis of mAbs</a></li><li><span class="icon-lt-pdf"></span><a target="_blank" href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/an-21781-lc-ms-ptm-nistmab-rm-8671-an21781-en.pdf">Investigating Process-Related Post-Translational Modifications in NIST mAb RM 8671 Using High-Throughput Peptide Mapping Analysis</a></li><li><span class="icon-lt-pdf"></span><a target="_blank" href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/an-21767-lc-ms-surrogate-peptide-bioanalysis-an21767-en.pdf">A Fast and Simple Workflow for Surrogate Peptide Bioanalysis: NIST mAb Case Study</a></li><li><span class="icon-lt-pdf"></span><a target="_blank" href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/AN-21180-SP-SMART-Digest-Biomarker-AN21180-EN.pdf">Enhanced Digestion for Improved Biomarker Identification</a></li><li><span class="icon-lt-pdf"></span><a target="_blank" href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/AN-21504-SP-SMART-Digest-Digestion-Endpoint-AN21504-EN.pdf">Fast Digestion Method Optimization Using Innovative Trypsin Technology</a></li><li><span class="icon-lt-pdf"></span><a target="_blank" href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/AN-21682-SP-LC-MS-Peptide-Mapping-Proteins-AN21682-EN.pdf">High-Precision, Automated Peptide Mapping of Proteins</a></li><li><span class="icon-lt-pdf"></span><a target="_blank" href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/AN-1124-LC-Retention-Time-Peptide-Mapping-AN71612-EN.pdf">Highest Retention Time and Peak Area Reproducibility for Maximal Confidence in Peptide Mapping Experiments</a></li><li><span class="icon-lt-pdf"></span><a target="_blank" href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/AN-21688-SP-LC-MS-Peptide-Mapping-Intact-Protein-AN21688-EN.pdf">Robust and Reproducible Peptide Mapping and Intact Mass Analysis Workflows on a Single Instrument Platform</a></li><li><span class="icon-lt-pdf"></span><a target="_blank" href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/AN-21552-SP-SMART-Digest-Klotho-Plasma-AN21552-EN.pdf">Analysis of the Low-Abundance Plasma Biomarker Klotho in Less than Four Hours</a></li><li><span class="icon-lt-pdf"></span><a target="_blank" href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/ab-22016-smart-digest-trypsin-ab22016-en.pdf">In-Gel Digestion using the SMART Digest Trypsin Kit</a></li><li><span class="icon-lt-pdf"></span><a target="_blank" href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/an-22059-therapeutic-proteins-plasma-an22059-en.pdf">Simple and Sensitive Quantitation of Large Therapeutic Proteins in Plasma in 90 Minutes</a></li><li><span class="icon-lt-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/an-73684-lc-ms-igg1-mab-bioanalysis-an73684-en.pdf" target="_blank">A Fast and Simple Immuno-mass Spectrometry Method for Preclinical Bioanalysis for IgG1 mAb</a></li><li><span class="icon-lt-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/an-22107-lc-ms-smart-digest-human-igg-plasma-an22107-en.pdf" target="_blank">Application Note: Reproducible IA-LC-MS/MS Quantitation of Human IgG from Plasma with SMART Digest Fractionation Kits</a></li><li><span class="icon-lt-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/CMD/Application-Notes/cn-001731-pb-symphogen-protein-based-therapeutics-cn001731-en.pdf" target="_blank">Customer Note: Development of a systematic approach for improving tryptic digestion, recovery and chromatographic performance for mAb analysis</a></li></ul></div></div></div></div></div></div></div></div></div><script> $j(document).ready(function(){ $j('#1dcedbe99cc0415a86936a0a02f59155').on('hide', function(e) { $(e.target).find(".accordion-content").hide(); }); $j('#1dcedbe99cc0415a86936a0a02f59155').on('show', function(e) { $(e.target).find(".accordion-content").show(); }); }); </script></div></div></div><div class="parsys_column cq-colctrl-lt0-c1"><div container-id="cq-colctrl-lt0" comp-id="B1"><div class="accordion section"><div class="accordion" id="be6e7b04883742d289ff5e75f9daf606" style='margin-bottom: 0;'><div class="parsys"><div class="accordionitem section"><div class='accordion-group' ><div class='accordion-heading '><a class="accordion-toggle" data-toggle="collapse" data-parent="#be6e7b04883742d289ff5e75f9daf606" href="#faqs"><span class="caret"></span> Frequently Asked Questions (FAQs) </a></div><div class="accordion-body collapse " id="faqs"><div class="accordion-inner"><div class="accordion-content"><div class="itemParsys parsys"><div class="heading section"><h4> Frequently asked questions (FAQs) </h4></div><div class="text parbase section"><ul class="the-icons clearfix"><li><span class="icon-lt-pdf"></span><a target="_blank" href="https://assets.thermofisher.com/TFS-Assets/CMD/brochures/BR-21676-SMART-Digest-Soluble-FAQ-BR21676-EN.pdf">FAQs for SMART Digest Soluble Trypsin Kit</a></li><li><span class="icon-lt-pdf"></span><a target="_blank" href="https://assets.thermofisher.com/TFS-Assets/CMD/brochures/BR-21551-SMART-Digest-IA-FAQ-BR21551-EN.pdf">FAQs for SMART Digest IA Kits</a></li><li><span class="icon-lt-pdf"></span><a target="_blank" href="https://assets.thermofisher.com/TFS-Assets/CMD/Flyers/fl-21537-smart-digest-kit-faq-fl21537-en.pdf">FAQs for SMART Digest Kits</a></li></ul></div></div></div></div></div></div></div><div class="accordionitem section"><div class='accordion-group' ><div class='accordion-heading '><a class="accordion-toggle" data-toggle="collapse" data-parent="#be6e7b04883742d289ff5e75f9daf606" href="#manuals"><span class="caret"></span> Manuals </a></div><div class="accordion-body collapse " id="manuals"><div class="accordion-inner"><div class="accordion-content"><div class="itemParsys parsys"><div class="heading section"><h4> Manuals </h4></div><div class="text parbase section"><ul class="the-icons clearfix"><li><span class="icon-lt-pdf"></span><a target="_blank" href="https://assets.thermofisher.com/TFS-Assets/CMD/manuals/Man-21543-SMART-Digest-User-Man21543-EN.pdf">SMART Digest Kit User Manual</a></li><li><span class="icon-lt-pdf"></span><a target="_blank" href="https://assets.thermofisher.com/TFS-Assets/CMD/manuals/Man-21549-SMART-Digest-IA-User-Man21549-EN.pdf">SMART Digest ImmunoAffinity (IA) Kit User Manual</a></li></ul></div></div></div></div></div></div></div><div class="accordionitem section"><div class='accordion-group' ><div class='accordion-heading '><a class="accordion-toggle" data-toggle="collapse" data-parent="#be6e7b04883742d289ff5e75f9daf606" href="#workflow"><span class="caret"></span> Workflow </a></div><div class="accordion-body collapse " id="workflow"><div class="accordion-inner"><div class="accordion-content"><div class="itemParsys parsys"><div class="heading section"><h4> Workflow </h4></div><div class="text parbase section"><ul class="the-icons clearfix"><li><span class="icon-lt-pdf"></span><a target="_blank" href="https://assets.thermofisher.com/TFS-Assets/CMD/brochures/BR-72040-Peptide-Mapping-Workflows-BR72040-EN.pdf">Upgrade Your Peptide Mapping Workflows</a></li></ul></div></div></div></div></div></div></div><div class="accordionitem section"><div class='accordion-group' ><div class='accordion-heading '><a class="accordion-toggle" data-toggle="collapse" data-parent="#be6e7b04883742d289ff5e75f9daf606" href="#ebooks"><span 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