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Biomarker Discovery & Validation | Autoantibody Profiling
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srcset="https://sengenics.com/wp-content/uploads/2022/03/istockphoto-1168042197-2048x2048-1-1.png 600w, https://sengenics.com/wp-content/uploads/2022/03/istockphoto-1168042197-2048x2048-1-1-300x274.png 300w" sizes="(max-width: 600px) 100vw, 600px" /></div></div></div></div><div class='av-flex-placeholder'></div><div class='flex_column av-l0kai17f-fd5f66cc0e710ff3ec20e9e9cfe0d253 av_three_fifth avia-builder-el-3 el_after_av_two_fifth avia-builder-el-last flex_column_table_cell av-equal-height-column av-align-middle av-animated-generic right-to-left ' ><section class='av_textblock_section av-l0kagkad-511ea5f70cf9c775b8d60dce5b6f35d5' itemscope="itemscope" itemtype="https://schema.org/CreativeWork" ><div class='avia_textblock' itemprop="text" ><h2>Enriched with Disease-Relevant Antigens</h2> <p>Disease processes trigger cellular and protein changes long before symptoms arise. The immune system, constantly vigilant, detects these changes and marks them with antibodies. Profiling these antibodies is crucial for identifying targetable and exploitable biomarkers: pathogenic antibodies, protective antibodies, and protein antigens.</p> <p>Our advanced microarrays are enriched with protein antigens involved in critical biological processes such as signaling, metabolism, gene expression, growth, and apoptosis—processes central to nearly all diseases. This targeted approach ensures the discovery of the most relevant biomarkers for early detection and treatment strategies.</p> </div></section></div></div><!--close column table wrapper. Autoclose: 1 --> </div></div></main><!-- close content main element --></div></div><div id='av-tab-section-1' class='av-tab-section-container entry-content-wrapper main_color av-tab-no-transition av-tab-above-content avia-builder-el-5 el_after_av_section el_before_av_section tab-section-not-first container_wrap fullsize' ><div class='av-tab-section-outer-container av-1ufpyf-48b5fd67da88c530010b8c0d515d4d67'><div class='av-tab-section-tab-title-container avia-tab-title-padding-default' role='tablist'><a href='#i-ome-cancer-microarray' data-av-tab-section-title='1' class='av-section-tab-title av-active-tab-title no-scroll av-l0katzju-156d0322d2f14e4d0a88921c600cfc12 av-tab-no-icon av-tab-no-image ' role='tab' tabindex='0' aria-controls='av-tab-section-1-1'><span class='av-outer-tab-title'><span class='av-inner-tab-title'>i-Ome Cancer Microarray</span></span><span class="av-tab-arrow-container"><span></span></span></a><a href='#i-ome-discovery-microarray' data-av-tab-section-title='2' class='av-section-tab-title av-l0katta3-4d41869576ba4d7010079cb0ba9383a7 av-tab-no-icon av-tab-no-image ' role='tab' tabindex='0' aria-controls='av-tab-section-1-2'><span class='av-outer-tab-title'><span class='av-inner-tab-title'>i-Ome Discovery Microarray</span></span><span class="av-tab-arrow-container"><span></span></span></a><a href='#pan-autoimmune-microarray' data-av-tab-section-title='3' class='av-section-tab-title av-l0kau5g9-76cd64ba25fe03cfedb5997eecf74fbe av-tab-no-icon av-tab-no-image ' role='tab' tabindex='0' aria-controls='av-tab-section-1-3'><span class='av-outer-tab-title'><span class='av-inner-tab-title'>Pan-Autoimmune Microarray</span></span><span class="av-tab-arrow-container"><span></span></span></a><a href='#citrullination-assay' data-av-tab-section-title='4' class='av-section-tab-title av-l0kau5g9-b355336cead8c46657d04e6aca839f62 av-tab-no-icon av-tab-no-image ' role='tab' tabindex='0' aria-controls='av-tab-section-1-4'><span class='av-outer-tab-title'><span class='av-inner-tab-title'>Citrullination Assay</span></span><span class="av-tab-arrow-container"><span></span></span></a><a href='#oncorex-p53-cancer-microarray' data-av-tab-section-title='5' class='av-section-tab-title av-l0kau5g9-b67e26a34bafb8b2f4e1fe95815c49fb av-tab-no-icon av-tab-no-image ' role='tab' tabindex='0' aria-controls='av-tab-section-1-5'><span class='av-outer-tab-title'><span class='av-inner-tab-title'>OncoRex p53 Cancer Microarray</span></span><span class="av-tab-arrow-container"><span></span></span></a></div><div class='av-tab-section-inner-container avia-section-default' style='width:500vw; left:0%;'><span class="av_prev_tab_section av_tab_navigation"></span><span class="av_next_tab_section av_tab_navigation"></span> <div id='av-tab-section-1-1' class='av-layout-tab av-l0katzju-156d0322d2f14e4d0a88921c600cfc12 av-animation-delay-container avia-builder-el-6 el_before_av_tab_sub_section avia-builder-el-first av-active-tab-content __av_init_open ' data-av-tab-section-content="1" data-tab-section-id='i-ome-cancer-microarray'><div class="av-layout-tab-inner"><div class="container"> <div class='flex_column_table av-l0kz6ua8-218493da00f0158bb1dc24fdf56bf42d sc-av_two_third av-equal-height-column-flextable'><div class='flex_column av-l0kz6ua8-218493da00f0158bb1dc24fdf56bf42d av_two_third avia-builder-el-7 el_before_av_one_third avia-builder-el-first first flex_column_table_cell av-equal-height-column av-align-top ' ><section class='av_textblock_section av-l0kz6p46-9d0e6c213be4b7fe74239bf0cba8e3fa' itemscope="itemscope" itemtype="https://schema.org/CreativeWork" ><div class='avia_textblock' itemprop="text" ><h2>Advance Cancer Insights with i-Ome<sup><small>®</small></sup> Cancer</h2> <p><strong>i-Ome Cancer</strong> is the largest and most advanced cancer-focused protein microarray on the market, designed to profile autoantibodies against 500+ antigens simultaneously, with exceptional precision. These protein antigens were meticulously selected for their significance in cancer, encompassing tissue and pathway relevance, therapeutic targets, cytokines and chemokines, cancer-driver proteins, prognostic indicators, cancer-testis antigens, B-cell and autoantibody targets, and ectopic expression.</p> <p>This robust platform is ideal for uncovering disease mechanisms, guiding vaccine and drug development, and advancing early cancer detection. With the capacity to analyze two <a href="https://sengenics.com/services/systems-serology/">antibody isotypes</a> simultaneously (IgG, IgA, IgM), i-Ome Cancer offers more than twice the coverage of its predecessor, providing deeper and more comprehensive disease insights.</p> <p>Sengenics protein microarrays leverage proprietary <a href="https://sengenics.com/technology/krex-protein-folding-technology/">KREX<sup><small>®</small></sup> technology</a> to guarantee protein integrity, eliminating non-specific binding and enhancing signal clarity.</p> <p><strong><a href="https://sengenics.com/resources/protein-list/">View the complete list of proteins</a></strong></p> </div></section> <div class='hr av-lz8e80qi-72a4617b8a27b5914ffbf311e7675275 hr-invisible avia-builder-el-9 el_after_av_textblock el_before_av_textblock '><span class='hr-inner '><span class="hr-inner-style"></span></span></div> <section class='av_textblock_section av-lz8e7mep-7b68062f6484dc7274adcebfa54c9f97' itemscope="itemscope" itemtype="https://schema.org/CreativeWork" ><div class='avia_textblock' itemprop="text" ><div class="flex-shrink-0 flex flex-col relative items-end"> <div> <div class="pt-0"> <div class="gizmo-shadow-stroke flex h-8 w-8 items-center justify-center overflow-hidden rounded-full"> <div class="h-full w-full"> <div class="gizmo-shadow-stroke overflow-hidden rounded-full"><strong>Get your FREE white paper today!</strong></div> <div class="gizmo-shadow-stroke overflow-hidden rounded-full">Discover how cancer-induced autoantibodies enhance early diagnosis, predict treatment response, and guide drug development.</div> </div> </div> </div> </div> </div> </div></section> <div class='hr av-3a1no0-46c3af02c42644b979ff64cb6c59d0d1 hr-invisible avia-builder-el-11 el_after_av_textblock el_before_av_button '><span class='hr-inner '><span class="hr-inner-style"></span></span></div> <div class='avia-button-wrap avia-button-left avia-builder-el-12 el_after_av_hr avia-builder-el-last ' ><a href='https://sengenics.com/download-cancer-white-paper-lp01-0624/' class='avia-button av-lz8e9ttz-dcd840e0847fef23acb4984efa57c2e5 avia-icon_select-no avia-size-small avia-position-left avia-color-theme-color' target="_blank" rel="noopener noreferrer"><span class='avia_iconbox_title' >Read White Paper</span></a></div></div><div class='av-flex-placeholder'></div><div class='flex_column av-1la0cv-2135aa98586dbd36d684665bc735417e av_one_third avia-builder-el-13 el_after_av_two_third avia-builder-el-last flex_column_table_cell av-equal-height-column av-align-top ' ><div class='hr av-lz83k14w-7098accea97552c65f3b1e381425fd54 hr-invisible avia-builder-el-14 el_before_av_image avia-builder-el-first '><span class='hr-inner '><span class="hr-inner-style"></span></span></div> <div class='avia-image-container av-l0kz7fml-dbc53522c779896679707f41067f97e3 av-styling- avia-align-center avia-builder-el-15 el_after_av_hr avia-builder-el-last ' itemprop="image" itemscope="itemscope" itemtype="https://schema.org/ImageObject" ><div class="avia-image-container-inner"><div class="avia-image-overlay-wrap"><img decoding="async" class='wp-image-3048 avia-img-lazy-loading-not-3048 avia_image' src="https://sengenics.com/wp-content/uploads/2024/08/i-Ome-Cancer-20240801-Cancer-type-distribution-vertical-1120x2048.jpg" alt='Profiling against cancer antigens' title='Profiling against cancer antigens' height="2048" width="1120" itemprop="thumbnailUrl" srcset="https://sengenics.com/wp-content/uploads/2024/08/i-Ome-Cancer-20240801-Cancer-type-distribution-vertical-1120x2048.jpg 1120w, https://sengenics.com/wp-content/uploads/2024/08/i-Ome-Cancer-20240801-Cancer-type-distribution-vertical-164x300.jpg 164w, https://sengenics.com/wp-content/uploads/2024/08/i-Ome-Cancer-20240801-Cancer-type-distribution-vertical-563x1030.jpg 563w, https://sengenics.com/wp-content/uploads/2024/08/i-Ome-Cancer-20240801-Cancer-type-distribution-vertical-768x1404.jpg 768w, https://sengenics.com/wp-content/uploads/2024/08/i-Ome-Cancer-20240801-Cancer-type-distribution-vertical-840x1536.jpg 840w, https://sengenics.com/wp-content/uploads/2024/08/i-Ome-Cancer-20240801-Cancer-type-distribution-vertical-821x1500.jpg 821w, https://sengenics.com/wp-content/uploads/2024/08/i-Ome-Cancer-20240801-Cancer-type-distribution-vertical-386x705.jpg 386w, https://sengenics.com/wp-content/uploads/2024/08/i-Ome-Cancer-20240801-Cancer-type-distribution-vertical-scaled.jpg 1400w" sizes="(max-width: 1120px) 100vw, 1120px" /></div></div></div></div></div><!--close column table wrapper. Autoclose: 1 --></div></div></div><div id='av-tab-section-1-2' class='av-layout-tab av-l0katta3-4d41869576ba4d7010079cb0ba9383a7 av-animation-delay-container avia-builder-el-16 el_after_av_tab_sub_section el_before_av_tab_sub_section ' data-av-tab-section-content="2" data-tab-section-id='i-ome-discovery-microarray'><div class="av-layout-tab-inner"><div class="container"> <div class='flex_column_table av-l0kaon2k-125411737600ab00508ff381f9953932 sc-av_one_half av-equal-height-column-flextable'><div class='flex_column av-l0kaon2k-125411737600ab00508ff381f9953932 av_one_half avia-builder-el-17 el_before_av_one_half avia-builder-el-first first flex_column_table_cell av-equal-height-column av-align-top ' ><section class='av_textblock_section av-l0kanzib-9437747a1916537c46d5aaaaddc3e0ab' itemscope="itemscope" itemtype="https://schema.org/CreativeWork" ><div class='avia_textblock list-2col' itemprop="text" ><h2><span style="color: #333333;">Maximize Insights with<br /> i-Ome<sup><small>®</small></sup> Discovery</span></h2> <p><strong>i-Ome Discovery</strong> is Sengenics’s largest protein microarray, featuring 1800+ human protein antigens that represent a myriad of protein functional classes and disease categories for comprehensive biological and immunoproteomic insights. A perfect solution for biomarker discovery, i-Ome Discovery enables the simultaneous analysis of <a href="https://sengenics.com/services/systems-serology/">two antibody isotypes</a> (IgG, IgA, IgM) in a single assay, capturing up to 4000 data points.</p> <p>Sengenics protein microarrays leverage proprietary <a href="https://sengenics.com/technology/krex-protein-folding-technology/">KREX<sup>®</sup> technology</a> to guarantee protein integrity, eliminating non-specific binding and enhancing signal clarity.</p> <p><strong><a href="https://sengenics.com/resources/protein-list/">View the complete list of proteins</a></strong></p> </div></section></div><div class='av-flex-placeholder'></div><div class='flex_column av-1rwo6f-cd33855afa1ea456d95a3efbd5998a9b av_one_half avia-builder-el-19 el_after_av_one_half avia-builder-el-last flex_column_table_cell av-equal-height-column av-align-top ' ><div class='avia-image-container av-l0kaoh2h-b1e7121e62e3cf1afd6d2fd3d90d0315 av-styling- avia-align-center avia-builder-el-20 avia-builder-el-no-sibling ' itemprop="image" itemscope="itemscope" itemtype="https://schema.org/ImageObject" ><div class="avia-image-container-inner"><div class="avia-image-overlay-wrap"><img decoding="async" class='wp-image-2995 avia-img-lazy-loading-not-2995 avia_image' src="https://sengenics.com/wp-content/uploads/2024/07/i-Ome-Discovery-Protein-Functional-Classes-Disease-Areas-Pie-Chart-20240723-Updated-2-2048x1862.jpg" alt='High-Precision Immunoprofiling' title='High-Precision Immunoprofiling' height="1862" width="2048" itemprop="thumbnailUrl" srcset="https://sengenics.com/wp-content/uploads/2024/07/i-Ome-Discovery-Protein-Functional-Classes-Disease-Areas-Pie-Chart-20240723-Updated-2-2048x1862.jpg 2048w, https://sengenics.com/wp-content/uploads/2024/07/i-Ome-Discovery-Protein-Functional-Classes-Disease-Areas-Pie-Chart-20240723-Updated-2-300x273.jpg 300w, https://sengenics.com/wp-content/uploads/2024/07/i-Ome-Discovery-Protein-Functional-Classes-Disease-Areas-Pie-Chart-20240723-Updated-2-1030x936.jpg 1030w, https://sengenics.com/wp-content/uploads/2024/07/i-Ome-Discovery-Protein-Functional-Classes-Disease-Areas-Pie-Chart-20240723-Updated-2-768x698.jpg 768w, https://sengenics.com/wp-content/uploads/2024/07/i-Ome-Discovery-Protein-Functional-Classes-Disease-Areas-Pie-Chart-20240723-Updated-2-1536x1396.jpg 1536w, https://sengenics.com/wp-content/uploads/2024/07/i-Ome-Discovery-Protein-Functional-Classes-Disease-Areas-Pie-Chart-20240723-Updated-2-1500x1364.jpg 1500w, https://sengenics.com/wp-content/uploads/2024/07/i-Ome-Discovery-Protein-Functional-Classes-Disease-Areas-Pie-Chart-20240723-Updated-2-705x641.jpg 705w" sizes="(max-width: 2048px) 100vw, 2048px" /></div></div></div></div></div><!--close column table wrapper. Autoclose: 1 --></div></div></div><div id='av-tab-section-1-3' class='av-layout-tab av-l0kau5g9-76cd64ba25fe03cfedb5997eecf74fbe av-animation-delay-container avia-builder-el-21 el_after_av_tab_sub_section el_before_av_tab_sub_section ' data-av-tab-section-content="3" data-tab-section-id='pan-autoimmune-microarray'><div class="av-layout-tab-inner"><div class="container"> <div class='flex_column_table av-l0kz8lbr-4fa3642b0648f764f5f2fe0ec8af30ec sc-av_two_third av-equal-height-column-flextable'><div class='flex_column av-l0kz8lbr-4fa3642b0648f764f5f2fe0ec8af30ec av_two_third avia-builder-el-22 el_before_av_one_third avia-builder-el-first first flex_column_table_cell av-equal-height-column av-align-top ' ><section class='av_textblock_section av-l0kz8hp1-470cf23a5c20ab4d1c5a68de029ea8ea' itemscope="itemscope" itemtype="https://schema.org/CreativeWork" ><div class='avia_textblock' itemprop="text" ><h2>Expand Your Autoimmune Research</h2> <p>Harness the power of Sengenics’s <strong>Pan-Autoimmune Autoantigen Panel </strong>to transform your autoimmune research. Profile your samples against 100+ clinically relevant protein antigens linked to a wide array of autoimmune diseases, such as SLE, RA, Sjogren’s, and diabetes. Detect up to two <a href="https://sengenics.com/services/systems-serology/">antibody isotype</a>s (IgG, IgA, IgM) to these antigens simultaneously, providing an expansive and detailed view of autoimmune responses.</p> <p>Sengenics protein microarrays leverage proprietary <a href="https://sengenics.com/technology/krex-protein-folding-technology/">KREX<sup>®</sup> technology</a> to guarantee protein integrity, eliminating non-specific binding and enhancing signal clarity.</p> <p><strong><a href="https://sengenics.com/resources/protein-list/">View the complete list of proteins</a></strong></p> </div></section></div><div class='av-flex-placeholder'></div><div class='flex_column av-1e99lb-448279543f6e8152f2c088fc03126aea av_one_third avia-builder-el-24 el_after_av_two_third avia-builder-el-last flex_column_table_cell av-equal-height-column av-align-top ' ><div class='hr av-5ib3q8-36e10a4ad0d55f958dfa1d97fbb978cb hr-invisible avia-builder-el-25 el_before_av_image avia-builder-el-first '><span class='hr-inner '><span class="hr-inner-style"></span></span></div> <div class='avia-image-container av-l0kz8ywy-ec52d5cd65010a712be427205f2d5349 av-styling- avia-align-center avia-builder-el-26 el_after_av_hr avia-builder-el-last ' itemprop="image" itemscope="itemscope" itemtype="https://schema.org/ImageObject" ><div class="avia-image-container-inner"><div class="avia-image-overlay-wrap"><img decoding="async" class='wp-image-3029 avia-img-lazy-loading-not-3029 avia_image' src="https://sengenics.com/wp-content/uploads/2024/07/Autoimmune-Disease-Autoantigen-Panel.png" alt='Autoimmune disease autoantibody screening includes SLE, RA, Sjogren’s, and diabetes among several others' title='Autoimmune disease autoantibody screening includes SLE, RA, Sjogren’s, and diabetes among several others' height="540" width="600" itemprop="thumbnailUrl" srcset="https://sengenics.com/wp-content/uploads/2024/07/Autoimmune-Disease-Autoantigen-Panel.png 600w, https://sengenics.com/wp-content/uploads/2024/07/Autoimmune-Disease-Autoantigen-Panel-300x270.png 300w" sizes="(max-width: 600px) 100vw, 600px" /></div></div></div></div></div><!--close column table wrapper. Autoclose: 1 --></div></div></div><div id='av-tab-section-1-4' class='av-layout-tab av-l0kau5g9-b355336cead8c46657d04e6aca839f62 av-animation-delay-container avia-builder-el-27 el_after_av_tab_sub_section el_before_av_tab_sub_section ' data-av-tab-section-content="4" data-tab-section-id='citrullination-assay'><div class="av-layout-tab-inner"><div class="container"> <div class='flex_column_table av-l0kz8lbr-4fa3642b0648f764f5f2fe0ec8af30ec sc-av_two_third av-equal-height-column-flextable'><div class='flex_column av-l0kz8lbr-4fa3642b0648f764f5f2fe0ec8af30ec av_two_third avia-builder-el-28 el_before_av_one_third avia-builder-el-first first flex_column_table_cell av-equal-height-column av-align-top ' ><section class='av_textblock_section av-l0kz8hp1-470cf23a5c20ab4d1c5a68de029ea8ea' itemscope="itemscope" itemtype="https://schema.org/CreativeWork" ><div class='avia_textblock' itemprop="text" ><h2>Profile Autoantibodies to Citrullinated Proteins</h2> <p>Explore the immune response to inflammation and cellular damage with our unique citrullination assay. Compatible with select Sengenics’s protein microarrays, this assay enables precise detection of autoantibodies targeting citrullinated proteins implicated in various diseases, from autoimmune to neurodegenerative disorders.</p> <p>Gain insight into the role of citrullination in disease and its potential in refining precision medicine in our detailed white paper.</p> </div></section> <div class='hr av-lugk4js4-9321d68a8d129c999b75a00aadd84efc hr-invisible avia-builder-el-30 el_after_av_textblock el_before_av_button '><span class='hr-inner '><span class="hr-inner-style"></span></span></div> <div class='avia-button-wrap avia-button-left avia-builder-el-31 el_after_av_hr avia-builder-el-last ' ><a href='https://sengenics.com/download-citrullination-white-paper-lp01-0424/' class='avia-button av-lugk1bue-c0ad3d4163855529d26ad49574a3aa33 avia-icon_select-no avia-size-medium avia-position-left avia-color-theme-color' target="_blank" rel="noopener noreferrer"><span class='avia_iconbox_title' >Read White Paper</span></a></div></div><div class='av-flex-placeholder'></div><div class='flex_column av-1e99lb-448279543f6e8152f2c088fc03126aea av_one_third avia-builder-el-32 el_after_av_two_third avia-builder-el-last flex_column_table_cell av-equal-height-column av-align-top ' ><div class='hr av-442rf4-6f9cc802b04bc3a26b19e45a8d84fc0b hr-invisible avia-builder-el-33 el_before_av_image avia-builder-el-first '><span class='hr-inner '><span class="hr-inner-style"></span></span></div> <div class='avia-image-container av-l0kz8ywy-41420c0f914f88f2a1f2408ccda091a2 av-styling- avia-align-center avia-builder-el-34 el_after_av_hr avia-builder-el-last ' itemprop="image" itemscope="itemscope" itemtype="https://schema.org/ImageObject" ><div class="avia-image-container-inner"><div class="avia-image-overlay-wrap"><img decoding="async" class='wp-image-3030 avia-img-lazy-loading-not-3030 avia_image' src="https://sengenics.com/wp-content/uploads/2024/07/citrullination.png" alt='Autoimmune disease autoantibody screening includes SLE, RA, Sjogren’s, and diabetes among several others' title='Autoimmune disease autoantibody screening includes SLE, RA, Sjogren’s, and diabetes among several others' height="540" width="600" itemprop="thumbnailUrl" srcset="https://sengenics.com/wp-content/uploads/2024/07/citrullination.png 600w, https://sengenics.com/wp-content/uploads/2024/07/citrullination-300x270.png 300w" sizes="(max-width: 600px) 100vw, 600px" /></div></div></div></div></div><!--close column table wrapper. Autoclose: 1 --></div></div></div><div id='av-tab-section-1-5' class='av-layout-tab av-l0kau5g9-b67e26a34bafb8b2f4e1fe95815c49fb av-animation-delay-container avia-builder-el-35 el_after_av_tab_sub_section avia-builder-el-last ' data-av-tab-section-content="5" data-tab-section-id='oncorex-p53-cancer-microarray'><div class="av-layout-tab-inner"><div class="container"> <div class='flex_column_table av-l0kz8lbr-4fa3642b0648f764f5f2fe0ec8af30ec sc-av_two_third av-equal-height-column-flextable'><div class='flex_column av-l0kz8lbr-4fa3642b0648f764f5f2fe0ec8af30ec av_two_third avia-builder-el-36 el_before_av_one_third avia-builder-el-first first flex_column_table_cell av-equal-height-column av-align-top ' ><section class='av_textblock_section av-l0kz8hp1-470cf23a5c20ab4d1c5a68de029ea8ea' itemscope="itemscope" itemtype="https://schema.org/CreativeWork" ><div class='avia_textblock' itemprop="text" ><h2>Elevate Your p53 Screening with the OncoRex p53 Cancer Array</h2> <p>Target the most commonly mutated protein in cancer with the <b>OncoRex</b><b> p53 Cancer Array</b>. Featuring 100+ p53 wildtype and mutant variants, this array enables precise screening of therapeutic antibodies and protein-binding compounds. Measure their impact on p53’s DNA binding ability and accelerate your immuno-oncology drug development.</p> <p><a href="https://sengenics.com/resources/protein-list/" target="_blank" rel="noopener"><b>View the complete list of proteins</b></a></p> </div></section> <div class='hr av-lugk4js4-9321d68a8d129c999b75a00aadd84efc hr-invisible avia-builder-el-38 el_after_av_textblock avia-builder-el-last '><span class='hr-inner '><span class="hr-inner-style"></span></span></div></div><div class='av-flex-placeholder'></div><div class='flex_column av-1e99lb-448279543f6e8152f2c088fc03126aea av_one_third avia-builder-el-39 el_after_av_two_third avia-builder-el-last flex_column_table_cell av-equal-height-column av-align-top ' ><div class='hr av-2us3ps-c258ba86bdca5457ba3c24f1cc896609 hr-invisible avia-builder-el-40 el_before_av_image avia-builder-el-first '><span class='hr-inner '><span class="hr-inner-style"></span></span></div> <div class='avia-image-container av-l0kz8ywy-d1b385f3f501c7faae3670ad7f765826 av-styling- avia-align-center avia-builder-el-41 el_after_av_hr avia-builder-el-last ' itemprop="image" itemscope="itemscope" itemtype="https://schema.org/ImageObject" ><div class="avia-image-container-inner"><div class="avia-image-overlay-wrap"><img decoding="async" class='wp-image-3031 avia-img-lazy-loading-not-3031 avia_image' src="https://sengenics.com/wp-content/uploads/2024/07/OncoRex-p53-Cancer-Microarray-1.png" alt='Autoimmune disease autoantibody screening includes SLE, RA, Sjogren’s, and diabetes among several others' title='Autoimmune disease autoantibody screening includes SLE, RA, Sjogren’s, and diabetes among several others' height="540" width="600" itemprop="thumbnailUrl" srcset="https://sengenics.com/wp-content/uploads/2024/07/OncoRex-p53-Cancer-Microarray-1.png 600w, https://sengenics.com/wp-content/uploads/2024/07/OncoRex-p53-Cancer-Microarray-1-300x270.png 300w" sizes="(max-width: 600px) 100vw, 600px" /></div></div></div></div></div><!--close column table wrapper. Autoclose: 1 --></div></div></div></div></div></div><div id='av_section_2' class='avia-section av-l0kbhus6-81c5df6c718d8f61452c9c9b76086b37 main_color avia-section-large avia-no-border-styling avia-builder-el-42 el_after_av_tab_section el_before_av_section bubble-row avia-full-contain avia-bg-style-scroll container_wrap fullsize' data-section-bg-repeat='contain'><div class='container av-section-cont-open' ><div class='template-page content av-content-full alpha units'><div class='post-entry post-entry-type-page post-entry-2016'><div class='entry-content-wrapper clearfix'> <div class='flex_column av-4j05r-305844d110a8de299c6bbdab3ff7f227 av_one_full avia-builder-el-43 avia-builder-el-no-sibling first flex_column_div ' ><section class='av_textblock_section av-l0kbi6ap-7e43a18aec2ec0a16e8b78efcf050901' itemscope="itemscope" itemtype="https://schema.org/CreativeWork" ><div class='avia_textblock' itemprop="text" ><h3 style="text-align: center;"><strong>Don’t see what you need? Learn about our <a href="https://sengenics.com/services/custom-protein-arrays/">Custom Protein Microarrays</a>.</strong></h3> </div></section></div> </p> </div></div></div><!-- close content main div --></div></div><div id='av_section_3' class='avia-section av-l0kben29-49e7d9561a6e93bf054e3ca396b4362e main_color avia-section-large avia-no-border-styling avia-builder-el-45 el_after_av_section el_before_av_section avia-full-stretch avia-bg-style-scroll container_wrap fullsize' data-section-bg-repeat='stretch'><div class='container av-section-cont-open' ><div class='template-page content av-content-full alpha units'><div class='post-entry post-entry-type-page post-entry-2016'><div class='entry-content-wrapper clearfix'> <div class='flex_column av-l0kbcvzn-a18923d9e74657f36fa67d129d565451 av_one_half avia-builder-el-46 el_before_av_one_half avia-builder-el-first first flex_column_div av-animated-generic bottom-to-top ' ><section class='av_textblock_section 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SMAD pathways define new subgroups in systemic lupus erythematosus →</a></p> <p><a href="https://youtu.be/NCaE-uCesbE">Video: B Cell Repertoire in Determining Responses to Checkpoint Blockade in NSCLC by Prof. Middleton & Dr. Patel → </a></p> </div></section></div> </div></div></div><!-- close content main div --></div></div><div id='av_section_4' class='avia-section av-45wpj-e85c8d545e1c688de5bd2a26ab6a600e main_color avia-section-default avia-no-border-styling avia-builder-el-50 el_after_av_section avia-builder-el-last unset-row cta-row avia-full-stretch avia-bg-style-scroll container_wrap fullsize' data-section-bg-repeat='stretch'><div class='container av-section-cont-open' ><div class='template-page content av-content-full alpha units'><div class='post-entry post-entry-type-page post-entry-2016'><div class='entry-content-wrapper clearfix'> <div class='avia-image-container av-vg16v-91c7f31ec4f9eecff6907656bfbbb6ed av-styling- avia_animated_image avia_animate_when_almost_visible 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<div id="popmake-2185" class="pum-container popmake theme-1975 pum-responsive pum-responsive-medium responsive size-medium"> <div class="pum-content popmake-content" tabindex="0"> <div class='gf_browser_gecko gform_wrapper gravity-theme gform-theme--no-framework' data-form-theme='gravity-theme' data-form-index='0' id='gform_wrapper_20' > <div class='gform_heading'> <p class='gform_description'></p> <p class='gform_required_legend'>"<span class="gfield_required gfield_required_asterisk">*</span>" indicates required fields</p> </div><form method='post' enctype='multipart/form-data' id='gform_20' action='/services/autoantibody-biomarker-profiling/' data-formid='20' novalidate> <input type='hidden' class='gforms-pum' value='{"closepopup":false,"closedelay":0,"openpopup":false,"openpopup_id":0}' /> <div class='gform-body gform_body'><div id='gform_fields_20' class='gform_fields top_label form_sublabel_below description_below validation_below'><div id="field_20_12" class="gfield 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