NIST Genome Editing Consortium

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Please see below for more detailed information on current activities.\r\n\r\nMEMBER BENEFITS\r\n\r\n\r\n\tAccess to a neutral forum for addressing pre-competitive needs\r\n\tParticipation in the development of experimental benchmarks, guidelines, and terminology\r\n\tAccess to tools developed by the consortium ahead of public release\r\n\tInstitutional representation on consortium steering committee\r\n\r\n\r\nBECOME A MEMBER \r\n\r\n\r\n\tAnnual fee of $20,000 or in-kind support of equivalent value\r\n\tParticipants will sign a Cooperative Research and Development Agreement\r\n\tComplete Letter of Interest Form \r\n\r\n\r\n聽聽Notice of NIST鈥檚 Genome Editing Consortium Establishment\r\n聽聽Notice of NIST鈥檚 Genome Editing Consortium Extension\r\n\r\nPAST EVENTS\r\n\r\n\r\n\t\r\n\t2023聽NIST-FDA Workshops on Measurements and Standards for Advanced Therapy\r\n\t\r\n\t\r\n\t2019 NIST Genome Editing Workshop\r\n\t\r\n\t\r\n\t2018 NIST-FDA Genome Editing Workshop \r\n\t\r\n\t\r\n\t2016 NIST Genome Editing Standards Workshop:聽Agenda,聽Workshop Report", "image": { "@type": "ImageObject", "representativeOfPage": "True", "url": "https://web.archive.org/web/20240121215110/https://www.nist.gov/sites/default/files/images/2017/06/30/bigstock-177254398.jpg", "width": "220", "height": "119" }, "datePublished": "2018-01-11T07:00-05:00", "dateModified": "2024-01-17T13:39-05:00" } ] }</script> <meta name="nist_search_bundle" class="elastic" content="project_program"/> <link rel="icon" href="/web/20240121215110im_/https://www.nist.gov/themes/custom/nist_www/favicon.ico" type="image/vnd.microsoft.icon"/> <title>NIST Genome Editing Consortium | NIST</title> <link rel="stylesheet" media="all" 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class="usa-button usa-button--accent-cool" href="/web/20240121215110/https://www.nist.gov/laboratories/projects-programs">PROJECTS/PROGRAMS</a> </div> <div class="nist-block"> <h1 class="nist-page__title">NIST Genome Editing Consortium</h1> </div> <div class="nist-block">  <div data-elastic-exclude class="nist-block nist-social__wrapper"> <h2 class="nist-social__title">Share</h2> <div class="social-media-sharing"> <div class="nist-social__wrapper--share"> <div> <a target="_blank" rel="noopener" href="https://web.archive.org/web/20240121215110/https://www.facebook.com/share.php?u=https://www.nist.gov/programs-projects/nist-genome-editing-consortium" title="Facebook" class="nist-social nist-social--facebook-gray"> <span>Facebook</span> </a> </div> <div> <a target="_blank" rel="noopener" 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</div> </div>  </div> </div> </div> <div class="grid-container margin-top-4"> <div class="grid-row grid-gap-6"> <div class="nist-page__region nist-page__region--content tablet-lg:grid-col-8"> <div class="nist-block gray-box"> <div class="text-long"> <h2>Summary</h2> <p><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">The National Institute of Standards and Technology Genome Editing Consortium addresses the measurements and standards needed to increase confidence and lower the risk of utilizing genome editing technologies in research and commercial products. This consortium is currently active. Please see below for more detailed information on current activities.</span></span></span></span></p> <p><span><span><span><strong><span lang="EN" xml:lang="EN" xml:lang="EN">MEMBER BENEFITS</span></strong></span></span></span></p> <ul><li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Access to a neutral forum for addressing pre-competitive needs</span></span></span></span></li> <li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Participation in the development of experimental benchmarks, guidelines, and terminology</span></span></span></span></li> <li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Access to tools developed by the consortium ahead of public release</span></span></span></span></li> <li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Institutional representation on consortium steering committee</span></span></span></span></li> </ul><p><span><span><span><strong><span lang="EN" xml:lang="EN" xml:lang="EN">BECOME A MEMBER </span></strong></span></span></span></p> <ul><li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Annual fee of $20,000 or in-kind support of equivalent value</span></span></span></span></li> <li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Participants will sign a Cooperative Research and Development Agreement</span></span></span></span></li> <li><span><span><span><a href="https://web.archive.org/web/20240121215110/https://docs.google.com/forms/d/1tCADRDgjBb-EFS9mZdbAcC0HzJzI12jTXs9wwu85LvA/viewform?c=0&w=1&edit_requested=true"><span><span>Complete Letter of Interest Form</span></span></a> </span></span></span></li> </ul><p><span><span><span>聽聽<a href="https://web.archive.org/web/20240121215110/https://www.federalregister.gov/documents/2018/01/11/2018-00315/notice-of-nists-consortium-for-the-advancement-of-genome-editing"><span><span>Notice</span></span></a><span lang="EN" xml:lang="EN" xml:lang="EN"> of NIST鈥檚 Genome Editing Consortium Establishment</span></span></span></span><br/><span><span><span>聽聽<a href="https://web.archive.org/web/20240121215110/https://www.federalregister.gov/documents/2021/02/02/2021-02136/notice-of-nists-consortium-for-the-advancement-of-genome-editing"><span><span>Notice</span></span></a><span lang="EN" xml:lang="EN" xml:lang="EN"> of NIST鈥檚 Genome Editing Consortium Extension</span></span></span></span></p> <p><strong>PAST EVENTS</strong></p> <ul><li> <p><a data-entity-substitution="canonical" data-entity-type="node" data-entity-uuid="fe9cc268-1aa1-4426-9284-b34b78811caa" href="/web/20240121215110/https://www.nist.gov/news-events/events/2023/11/nist-fda-workshops-measurements-and-standards-advanced-therapy" title="NIST-FDA Workshops on Measurements and Standards for Advanced Therapy">2023聽NIST-FDA Workshops on Measurements and Standards for Advanced Therapy</a></p> </li> <li> <p><span><span><span><a href="https://web.archive.org/web/20240121215110/https://www.nist.gov/news-events/events/2019/05/nist-genome-editing-workshop"><span><span>2019 NIST Genome Editing Workshop</span></span></a></span></span></span></p> </li> <li> <p><a href="https://web.archive.org/web/20240121215110/https://www.nist.gov/news-events/events/2018/04/nist-fda-genome-editing-workshop"><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN"><span>2018 </span></span></span></span></span></a><span><span><span><a href="https://web.archive.org/web/20240121215110/https://www.nist.gov/news-events/events/2018/04/nist-fda-genome-editing-workshop"><span><span>NIST-FDA Genome Editing Workshop </span></span></a></span></span></span></p> </li> <li> <p><span><span><span><span><span><span>2016 NIST Genome Editing Standards Workshop</span></span></span>:聽<a data-entity-substitution="canonical" data-entity-type="media" data-entity-uuid="22081a1f-5e0e-47fc-b27f-a7e2bc2a081b" href="/web/20240121215110/https://www.nist.gov/document/genes-workshop-5-2-16-agendapdf" title="GenES-Workshop-5-2-16-agenda.pdf" class="media-link-ga " data-file-url="/system/files/documents/mml/bbd/GenES-Workshop-5-2-16-agenda.pdf">Agenda</a>,聽<a href="https://web.archive.org/web/20240121215110/https://www.nist.gov/document/genomeeditingstandardsworkshop5-2-16reportpdf-0"><span><span><span>Workshop Report</span></span></span></a></span></span></span></p> </li> </ul> </div> </div> <div class="nist-block"> <h2 class="nist-block__title">Description</h2> <div class="text-with-summary"> <div class="margin-left-4 margin-bottom-2 align-right"> <figure class="nist-image"> <img src="/web/20240121215110im_/https://www.nist.gov/sites/default/files/styles/480_x_480_limit/public/images/2017/06/30/bigstock-177254398.jpg?itok=6LqSsJdy" width="480" height="261" alt="Genome editing technologies" loading="lazy" typeof="foaf:Image"/> <figcaption class="nist-image__caption"> <div data-caption-editable="true" class="nist-image__caption-content"> </div> </figcaption> </figure> </div> <p><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Targeted genome editing, a method used to alter the DNA of living cells at desired locations, is poised to revolutionize science and medicine. To fight diseases, novel genome edited therapeutics, including those for use in regenerative medicine and infectious diseases, are being developed. Many commercial applications including agriculture and chemical production, are also leveraging this technology. Whether genome editing will be used in healthcare, agriculture, or basic research, robust quantitative measurements are needed to enable high confidence characterization of DNA alterations. NIST has brought together experts across the genome editing field including stakeholders in industry, academia, and government to assess their measurement needs. These discussions have identified common pre-competitive measurements and standards needed to establish greater confidence in the characterization of genome editing outputs. The NIST-led Genome Editing Consortium has been established to address these needs.</span></span></span></span></p> <h2 class="nist-block__title">C<strong>ONSORTIUM GOALS</strong></h2> <ul><li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Evaluate genome editing assay pipelines</span></span></span></span></li> <li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Develop benchmark materials</span></span></span></span></li> <li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Generate benchmark data</span></span></span></span></li> <li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Develop suggested minimal information reporting for public studies</span></span></span></span></li> <li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Generate a common lexicon for genome editing studies </span></span></span></span></li> </ul><h2 class="nist-block__title"><strong>CONSORTIUM ORGANIZATION聽</strong></h2> <p>Three working groups with the following responsibilities:</p> <p><a data-entity-substitution="canonical" data-entity-type="node" data-entity-uuid="7ba85f77-7003-472d-bd9e-ec11ea938631" href="/web/20240121215110/https://www.nist.gov/programs-projects/nist-genome-editing-consortium-working-group-1-specificity-measurements" title="NIST Genome Editing Consortium: Working Group 1 - Specificity Measurements"><strong><em>Working Group 1: Specificity Measurements</em></strong></a></p> <ul><li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Design, generate, and evaluate cell and DNA based control materials and test via interlab analysis. Control materials will be used as聽benchmarks for assessing聽next-generation sequencing (NGS) pipelines and other platforms intended to identify induced genome editing events.</span></span></span></span></li> <li><span lang="EN" xml:lang="EN" xml:lang="EN"><span><span>Design and conduct controlled evaluations of existing assays for quantifying on- and off-target genome editing, with a robust and optimal experimental design aimed at assessing the sources of variability, repeatability, and reproducibility within an assay.</span></span></span></li> </ul><div class="grid-row grid-gap"> <div class="grid-col"> <p><a data-entity-substitution="canonical" data-entity-type="node" data-entity-uuid="40e8974f-1b88-4d1b-9e77-5a6ab224005b" href="/web/20240121215110/https://www.nist.gov/programs-projects/nist-genome-editing-consortium-working-group-2-data-metadata" title="NIST Genome Editing Consortium: Working Group 2 - Data & Metadata"><strong><em>Working Group 2: Data and Metadata</em></strong></a></p> <ol><li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Identify community norms for data formats and tools for benchmarking data analysis including in silico and experimental data sets.</span></span></span></span></li> <li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Determine the type of metadata that would be needed to be shared, housed, and interrogated from genome editing experiments.</span></span></span></span></li> </ol><p><a href="https://web.archive.org/web/20240121215110/https://www.nist.gov/programs-projects/nist-genome-editing-lexicon"><strong><em>Working Group 3: Lexicon</em></strong></a></p> <ol><li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Identify terms and related definitions to form a common genome editing community lexicon.</span></span></span></span></li> </ol><ol></ol><p>聽</p> </div> <div class="grid-col last"> <h2>聽</h2> <figure class="align-center nist-image--lightbox nist-image" data-lightbox="https://www.nist.gov/sites/default/files/styles/2800_x_2800_limit/public/images/2018/01/11/genome_editing_working_groups._v3jpg.jpg?itok=fKuiVLvB" data-media-id="418301"><img alt="Gene editing working group" height="391" loading="lazy" src="/web/20240121215110im_/https://www.nist.gov/sites/default/files/styles/480_x_480_limit/public/images/2018/01/11/genome_editing_working_groups._v3jpg.jpg?itok=CpGtUTRi" typeof="foaf:Image" width="395"/><figcaption class="nist-image__caption"><div class="nist-image__caption-content" data-caption-editable="true"> </div> </figcaption></figure><ol></ol></div> </div> <h2 class="nist-block__title"><strong>CONSORTIUM IMPACT</strong></h2> <ul><li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Shared genome editing physical benchmark materials for assay validation </span></span></span></span></li> <li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Community norms for minimum data reporting and tools for supporting data analysis</span></span></span></span></li> <li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Improved understanding of and confidence in detecting and quantifying on- and off-target genome editing</span></span></span></span></li> <li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Harmonized genome editing lexicon</span></span></span></span></li> </ul><h2 class="nist-block__title"><strong>CONSORTIUM MODEL</strong></h2> <ul><li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Convenes industry, academia, and government to identify and address measurement and standards needs across the genome editing field</span></span></span></span></li> <li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Enables members to work with NIST to develop measurement solutions and standards</span></span></span></span></li> <li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Leverages NIST expertise in measurement science, standards development, reference materials, technology development, and basic research</span></span></span></span></li> <li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Collaborates with related programs at other federal agencies</span></span></span></span></li> </ul><h2 class="nist-block__title"><strong>WHY NIST</strong></h2> <ul><li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Cross-disciplinary expertise in engineering, and the physical, information, chemical, and biological sciences</span></span></span></span></li> <li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">As a non-regulatory agency of the U.S. Department of Commerce, NIST does not impose standards; standards are accepted by consensus</span></span></span></span></li> <li><span><span><span><span lang="EN" xml:lang="EN" xml:lang="EN">Neutral convener for industry consortia, standards development organizations, federal labs, universities, public workshops, and interlaboratory comparability testing</span></span></span></span></li> </ul><ul></ul> </div> </div> <div class="nist-block">  <div data-elastic-exclude="" class="nist-tags"> <a href="/web/20240121215110/https://www.nist.gov/topic-terms/bioscience" hreflang="en">Bioscience</a>, <a href="/web/20240121215110/https://www.nist.gov/topic-terms/biomanufacturing" hreflang="en">Biomanufacturing</a>, <a href="/web/20240121215110/https://www.nist.gov/topic-terms/engineering-synthetic-biology" hreflang="en">Engineering / synthetic biology</a>, <a href="/web/20240121215110/https://www.nist.gov/topic-terms/genomics" hreflang="en">Genomics</a>, <a href="/web/20240121215110/https://www.nist.gov/topic-terms/precision-medicine" hreflang="en">Precision medicine</a> and <a href="/web/20240121215110/https://www.nist.gov/topic-terms/regenerative-medicine-and-advanced-therapy" hreflang="en">Regenerative medicine and advanced therapy</a></div>  </div> </div> <aside class="nist-page__region nist-page__region--sidebar-second tablet-lg:grid-col-4"> <div>  <div class="views-element-container nist-block nist-block--org" data-elastic-exclude=""> <h2 class="nist-block__title">Organizations</h2> <div><div class="js-view-dom-id-9e5204973cae8f1bbf87184e2ea2bf6b0664d2aece93c30c5c364d8716e3ab81"> <div class="nist-related-orgs"><div class="term-tree-list"> <ul class="term"><li><a href="/web/20240121215110/https://www.nist.gov/nist-organizations/nist-headquarters" class="selected" hreflang="en">NIST Headquarters</a></li><li><ul class="term"><li><a href="/web/20240121215110/https://www.nist.gov/nist-organizations/nist-headquarters/laboratory-programs" class="selected" hreflang="en">Laboratory Programs</a></li><li><ul class="term"><li><a href="/web/20240121215110/https://www.nist.gov/nist-organizations/nist-headquarters/laboratory-programs/material-measurement-laboratory" class="selected" hreflang="en">Material Measurement Laboratory</a></li><li><ul class="term"><li><a href="/web/20240121215110/https://www.nist.gov/nist-organizations/nist-headquarters/laboratory-programs/material-measurement-laboratory/biosystems" class="selected" hreflang="en">Biosystems and Biomaterials Division</a></li><li><ul class="term"><li><a href="/web/20240121215110/https://www.nist.gov/nist-organizations/nist-headquarters/laboratory-programs/material-measurement-laboratory-5" class="selected" hreflang="en">Biomarker and Genomic Sciences Group</a></li></ul></li></ul></li></ul></li></ul></li></ul> </div> </div> <div class="nist-related-orgs"></div> <div class="nist-related-orgs"></div> <div class="nist-related-orgs"></div> <div class="nist-related-orgs"></div> </div> </div> </div>  <div class="nist-block nist-block--contact"> <h2 class="nist-block__title">NIST Staff</h2> <div class="nist-field nist-field--label-hidden entity-reference nist-field--no-margin nist-field--link-list"> <div class="nist-field__items"> <div class="nist-field__item"> <a href="/web/20240121215110/https://www.nist.gov/people/samantha-maragh" rel="bookmark"><span>Samantha Maragh</span> </a> </div> <div class="nist-field__item"> <a href="/web/20240121215110/https://www.nist.gov/people/tara-eskandari" rel="bookmark"><span>Tara Eskandari</span> </a> </div> <div class="nist-field__item"> <a href="/web/20240121215110/https://www.nist.gov/people/natalia-kolmakova" rel="bookmark"><span>Natalia Kolmakova</span> </a> </div> <div class="nist-field__item"> <a href="/web/20240121215110/https://www.nist.gov/people/sierra-miller" rel="bookmark"><span>Sierra Miller</span> </a> </div> <div class="nist-field__item"> <a href="/web/20240121215110/https://www.nist.gov/people/simona-patange" rel="bookmark"><span>Simona Patange</span> </a> </div> <div class="nist-field__item"> <a href="/web/20240121215110/https://www.nist.gov/people/patty-kiesler" rel="bookmark"><span>Patty Kiesler</span> </a> </div> <div class="nist-field__item"> <a href="/web/20240121215110/https://www.nist.gov/people/zachary-trautt" rel="bookmark"><span>Zachary Trautt</span> </a> </div> <div class="nist-field__item"> <a href="/web/20240121215110/https://www.nist.gov/people/arlin-b-stoltzfus" rel="bookmark"><span>Arlin B Stoltzfus</span> </a> </div> <div class="nist-field__item"> <a href="/web/20240121215110/https://www.nist.gov/people/alessandro-tona" rel="bookmark"><span>Alessandro Tona</span> </a> </div> <div class="nist-field__item"> <a href="/web/20240121215110/https://www.nist.gov/people/sofiya-shevchenko" rel="bookmark"><span>Sofiya Shevchenko</span> </a> </div> </div> </div> </div> <div class="nist-block nist-block--contact"> <h2 class="nist-block__title">Contact</h2> <div class="nist-contact"> <ul class="nist-contact__items"> <li about="/people/samantha-maragh" class="nist-contact__item"> <div class="nist-contact__name"><a href="/web/20240121215110/https://www.nist.gov/people/samantha-maragh" title="View staff profile page">Samantha Maragh</a></div> <div> <a href="https://web.archive.org/web/20240121215110/mailto:samantha.maragh@nist.gov">samantha.maragh@nist.gov</a> </div> <div> (301) 975-4947 </div> </li> </ul> </div> </div> <div class="nist-block"> <h2 class="nist-block__title">Dates</h2> <div class="daterange"><time datetime="2018-01-11T12:00:00Z">January 2018</time> - <time datetime="2025-12-31T12:00:00Z">December 2025</time> </div> </div> <div class="nist-block"> <h2 class="nist-block__title">Project Status</h2> <div class="nist-badge display-inline-block margin-y-1 nist-badge--blue boolean">Ongoing</div> </div> <div class="nist-block"> <h2 class="nist-block__title">Related News</h2> <div class="nist-field nist-field--label-hidden nist-field--link-list entity-reference"> <div class="nist-field__items"> <div class="nist-field__item"><a href="/web/20240121215110/https://www.nist.gov/news-events/news/2018/02/public-private-partnership-develop-standards-regenerative-medicine" hreflang="en">Public-Private Partnership to Develop Standards for Regenerative Medicine</a></div> </div> </div> </div> <div class="nist-block"> <h2 class="nist-block__title">Related NIST Projects</h2> <div class="nist-field nist-field--label-hidden nist-field--link-list entity-reference"> <div class="nist-field__items"> <div class="nist-field__item"><a href="/web/20240121215110/https://www.nist.gov/programs-projects/nist-genome-editing-program" hreflang="en">NIST Genome Editing Program</a></div> <div class="nist-field__item"><a href="/web/20240121215110/https://www.nist.gov/programs-projects/nist-genome-editing-consortium-working-group-1-specificity-measurements" hreflang="en">NIST Genome Editing Consortium: Working Group 1 - Specificity Measurements</a></div> <div class="nist-field__item"><a href="/web/20240121215110/https://www.nist.gov/programs-projects/nist-genome-editing-consortium-working-group-2-data-metadata" hreflang="en">NIST Genome Editing Consortium: Working Group 2 - Data & Metadata</a></div> <div class="nist-field__item"><a href="/web/20240121215110/https://www.nist.gov/programs-projects/nist-genome-editing-lexicon" hreflang="en">NIST Genome Editing Lexicon</a></div> <div class="nist-field__item"><a href="/web/20240121215110/https://www.nist.gov/programs-projects/genome-bottle" hreflang="en">Genome in a Bottle</a></div> <div class="nist-field__item"><a href="/web/20240121215110/https://www.nist.gov/programs-projects/rmat-laboratory-programs" hreflang="en">RMAT Laboratory Programs</a></div> <div class="nist-field__item"><a href="/web/20240121215110/https://www.nist.gov/programs-projects/quantitative-flow-cytometry-measurements" hreflang="en">Quantitative Flow Cytometry Measurements</a></div> </div> </div> </div> <div class="nist-block"> <h2 class="nist-block__title">Other Projects</h2> <div class="text-long"><p><strong>News Articles</strong></p> <p><span><span><a href="https://web.archive.org/web/20240121215110/https://crisprmedicinenews.com/news/setting-standards-in-the-crispr-genome-editing-revolution-interview-samantha-maragh-nist/">Setting standards in the CRISPR genome editing revolution. Interview: Samantha Maragh (NIST)</a><br/><br/><a href="https://web.archive.org/web/20240121215110/https://crisprmedicinenews.com/news/creating-the-common-language-of-genome-editing/">Creating the common language of genome editing</a></span></span><br/><br/><a href="https://web.archive.org/web/20240121215110/https://cen.acs.org/pharmaceuticals/gene-therapy/Gene-editors-grapple-standardization/96/i21">Gene editors grapple with standardization</a><br/><br/><a href="https://web.archive.org/web/20240121215110/https://www.nature.com/articles/s41586-020-1978-5?proof=t">The promise and challenge of therapeutic genome editing</a></p></div> </div> <h2 class="nist-block__title"> CUSTOMERS/CONTRIBUTORS<br>/COLLABORATORS </h2> <div class="text-long"><p><strong><span><span><span><span>Genome Editing Consortium Members (as of 2024-01-17):</span></span></span></span></strong></p> <p><span><span><span><span><span><span>Abigail Wexner Research Institute at Nationwide Children's Hospital</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Agilent Technology, Inc.*</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Aldevron, LLC</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Applied StemCell, Inc.</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>AstraZeneca UK Limited</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Bio-Rad Laboratories, Inc.*</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Bionano Genomics, Inc.</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>BioSkryb Genomics, Inc.</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Bluebird Bio, Inc.*</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Broken String Biosciences Ltd</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Caribou Biosciences, Inc.</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Catalytic Data Science</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Cergentis</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>COBO Technologies</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>College of American Pathologists (CAP)聽</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>CRISPR Therapeutics, Inc.</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>CRISPRQC</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Cytosurge AG</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Defense Advanced Research Projects Agency (DARPA)</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Editas Medicine, Inc.</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Emerzene, Inc.</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>European Molecular Biology Laboratory, European (EMBL-EBI)</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>FDA CBER (Center for Biologics Evaluation and Research)</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>GeneGoCell, Inc.</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Genomic Vision*</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Illumina, Inc.</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Inscripta, Inc.*</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Integrated DNA Technologies, Inc.</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Intellia Therapeutics, Inc.</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>KromaTiD, Inc.</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Life Sciences Corporation (ThermoFisher Scientific) (Life Technologies Corporation)</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Lonza Walkersville, Inc. (Lonza AG)*</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Massachusetts General Hospital</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Metagenomi, Inc.</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Mission Bio, Inc.</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>National Institute of Health Somatic Cell Genome Editing (NIH SCGE)</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>National Institute of Neurological Disorders and Stroke (NIH/NINDS)</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>National Institute of Standards and Technology (NIST)</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>New England Biolabs, Inc. (NEB)</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Novartis Institutes for Biomedical Research, Inc.</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Pfizer, Inc.*</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Pioneer Hi-Bred International, Inc. (DowDuPont Agroscience (Corteva))*</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Precision Biosciences, Inc.</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Psomagen, Inc</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Resilience US, Inc.</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Revvity (formerly Horizon Discovery, Inc.)</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Sana Biotechnology, Inc.</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Sangamo Therapeutics, Inc.*</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Scribe Therapeutics Inc.</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>SeQure DX</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>St. Jude Children's Research Hospital聽</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Synthego Corporation</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>TwinStrand Biosciences, Inc.</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>UCSC (University of California Santa Cruz)</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>University of Utah</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>Verve Therapeutics, Inc.</span></span></span></span></span></span></p> <p><span><span><span><span><span><span>WhiteLab Genomics</span></span></span></span></span></span></p> <p><br/><em>Previous Members*</em></p></div> </div> </aside> </div> </div> <div class="grid-container"> <div class="nist-page__region nist-page__region--content-bottom"> <div class="nist-block"> <div class="text-italic font-sans-2xs"> Created June 30, 2017, Updated January 17, 2024 </div> </div> </div> </div> </section> </div> <div data-elastic-exclude>  <footer class="nist-footer padding-bottom-4"> <div class="grid-container nist-footer__info"> <div class="grid-row"> <div class="tablet:grid-col-6"> <div class="nist-footer__logo"> <a href="/web/20240121215110/https://www.nist.gov/" title="National Institute of Standards and Technology" rel="home"> <img class="nist-footer__logo-img" src="/web/20240121215110im_/https://www.nist.gov/libraries/nist-component-library/dist/img/logo/NIST-Logo-Brand-White.svg" alt="National Institute of Standards and Technology logo" width="300px" height="42px"/> </a> </div> <div class="nist-footer__contact"> <h3 class="nist-footer__contact-heading">HEADQUARTERS</h3> <address> 100 Bureau Drive<br> Gaithersburg, MD 20899<br> <a href="https://web.archive.org/web/20240121215110/tel:301-975-2000">301-975-2000</a> </address> <p> <a href="https://web.archive.org/web/20240121215110/mailto:do-webmaster@nist.gov">Webmaster</a> | <a href="https://web.archive.org/web/20240121215110/https://www.nist.gov/about-nist/contact-us">Contact Us</a> | <a href="https://web.archive.org/web/20240121215110/https://www.nist.gov/visit">Our Other Offices</a> </p> </div> </div> <div class="tablet:grid-col-6"> <div class="nist-footer__social-links"> <a class="nist-social nist-social--twitter-white" href="https://web.archive.org/web/20240121215110/https://twitter.com/NIST"> <span>Twitter</span> </a> <a class="nist-social nist-social--facebook-white" href="https://web.archive.org/web/20240121215110/https://www.facebook.com/NIST"> <span>Facebook</span> </a> <a class="nist-social nist-social--linkedin-white" href="https://web.archive.org/web/20240121215110/https://www.linkedin.com/company/nist"> <span>LinkedIn</span> </a> <a class="nist-social nist-social--instagram-white" href="https://web.archive.org/web/20240121215110/https://www.instagram.com/nist/"> <span>Instagram</span> </a> <a class="nist-social nist-social--youtube-white" href="https://web.archive.org/web/20240121215110/https://www.youtube.com/NIST"> <span>YouTube</span> </a> <a class="nist-social nist-social--giphy-white" href="https://web.archive.org/web/20240121215110/https://giphy.com/nist"> <span>Giphy</span> </a> <a class="nist-social nist-social--rss-white" href="https://web.archive.org/web/20240121215110/https://www.nist.gov/news-events/nist-rss-feeds"> <span>RSS Feed</span> </a> <a class="nist-social nist-social--envelope-white" href="https://web.archive.org/web/20240121215110/https://public.govdelivery.com/accounts/USNIST/subscriber/new"> <span>Mailing List</span> </a> </div> <div class="nist-footer__feedback"> How are we doing? 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