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<!DOCTYPE HTML PUBLIC "-//W3C//Dtd HTML 4.01 Transitional//EN"> <html> <head> <!-- Google tag (gtag.js) --> <script async src="https://www.googletagmanager.com/gtag/js?id=G-9H47X4K6P6"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-9H47X4K6P6'); </script> <link href="/css/style.css" type="text/css" rel="stylesheet"> <!--Include additional css, etc--> </head> <div id="header"> <body bgcolor="#ffffff" leftmargin=0 topmargin=0 marginwidth="0" marginheight="0" > <!-- Nav Bar --> <table width="915" cellpadding=0 cellspacing=0> <tr><td colspan=8 > <table cellpadding=2 cellspacing=0 width="100%" border=0> <TR> <td rowspan=2 colspan=8 valign=middle align="left"> <DIV style=" padding: 5px 5px 5px 5px;vertical-align: middle;"> <DIV style="float:left; display:table-cell; vertical-align: middle; text-align: center; padding: 10px 20px 5px 5px;"> <a href="/" target="_top"><img src="/images/logos/Panther_logo.jpg" ></a> </DIV> <p style="overflow:hidden;font-size:14px">The mission of the PANTHER knowledgebase is to support biomedical and other research by providing<BR> <b>comprehensive information about the evolution of protein-coding gene families</b>, particularly<BR> protein phylogeny, function and genetic variation impacting that function. <a href="/about.jsp">Learn more</a></p> </DIV> </td> </TR> </table> </td> </tr> <TR> <TD align = "left"><div><b>PANTHER19.0 Released. <a href="/news/news20240620.jsp"> Click</a> for more details.</b></div></TD> </TR> <TR><TD> </TD></TR> <TR> <TD colspan=8 bgcolor="#F0F2F5" valign=middle align="left" > <form name="quicksearch" method=GET onSubmit="javascript:submitQuickSearch();"> <input type="hidden" name="searchType" value="basic"> <input type="hidden" name="fieldName" value="all"> <input type="hidden" name="organism" value="all"> <table align="left" border="0" cellspacing="0" cellpadding="0" height="100%"> <tr> <td nowrap height=25><input type="text" name="fieldValue" placeholder="search keyword" size=25 style="font-size:14px;" autofocus></td> <td height=25> <select name="listType" style="font-size:14px;width:40"> <option selected value="-1">All</option> <option value="1">Genes and orthologs</option> <option value="8">Pathways</option> <option value="6">PANTHER families</option> <option value="5">Ontology terms</option> </select> </td> <td> <a class="buttonblueexactsize" name="gobutton" href="javascript:submitQuickSearch();" style="font-size:14px">Go</a></td> </tr> </table> </form> </TD> </TR> <TR> <TD colspan=5 bgcolor="#748CAD" height=25 align="left"> <TABLE cellpadding=0 cellspacing=0 height="100%" > <TR> <td bgcolor="#B8C6D8" width=1><img width=1 src="/images/spacer.gif"></TD> <TD nowrap class=headerTabs><A href="/" target="_top"> Home </A></TD> <TD bgcolor="#B8C6D8" width=1><img width=1 src="/images/spacer.gif"></TD> <TD nowrap class=headerTabs><a href="/about.jsp" target="_top"> About </A> </TD> <TD bgcolor="#B8C6D8" width=1><img width=1 src="/images/spacer.gif"></TD> <TD nowrap class=headerTabs><a href="/data/" target="_top"> Data Version </A> </TD> <TD bgcolor="#B8C6D8" width=1><img width=1 src="/images/spacer.gif"></TD> <TD nowrap class=headerTabs><a href="/tools/index.jsp" target="_top"> Tools </A> </TD> <TD bgcolor="#B8C6D8" width=1><img width=1 src="/images/spacer.gif"></TD> <TD nowrap class=headerTabs><a href="/services/index.jsp" target="_top"> API/Services </A> </TD> <TD bgcolor="#B8C6D8" width=1><img width=1 src="/images/spacer.gif"></TD> <TD nowrap class=headerTabs><a href="/publications.jsp" target="_top"> Publications </A> </TD> <TD bgcolor="#B8C6D8" width=1><img width=1 src="/images/spacer.gif"></TD> <TD nowrap class=headerTabs><a href="/workspace/" target="_top"> Workspace </A> </TD> <TD bgcolor="#B8C6D8" width=1><img width=1 src="/images/spacer.gif"></TD> <TD nowrap class=headerTabsSelected><a href="/downloads/index.jsp" target="_top"> Downloads </A> 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width="100%" border=0> <TR> <TD> </TD> <!--<TD><div><b><a href="/data/index.jsp">PANTHER17.0 Released</a>.</b></div></TD>--> <!-- <TD class=listResult valign=top>PANTHER version 17.0 contains <ul> <li>15,619 gene family phylogenetic trees -covering ~2 million genes</li> <li>from different species across the tree of life. <a href="/panther/summaryStats.jsp">more</a></li> </ul> </TD> <TD class=listResult valign=top>Each gene is classified by <ul> <li>protein class</li> <li>protein family and subfamily</li> <li>function (GO terms, pathways)</li> <li><a href="/data/">more</a></li> </TD> --> <TD align = "right" class="formLabel"> Current Release: <a href="/news/news20240620.jsp"><b>PANTHER 19.0</a></b> | <b><a href="/panther/index.jsp">15,683</a></b> family phylogenetic trees | <b><a href="/panther/summaryStats.jsp">144</a></b> species | <a href="/news/news20240620.jsp">News</a> <br><A href="/servlet/GenomeFunctionChartServlet?chartType=1&listType=1&annotType=5&species=Homo sapiens">Whole genome function views</A> </TD> </TR> </table> </div> <!-- end nav bar --> <!-- <table cellpadding=0 cellspacing=0> <tr> <td valign="top"> --!> <!-- </td> <td valign="top">--!><!--Main content page goes here--> <style type="text/css"> a.redLink:link { color: red; text-decoration: underline; } </style> <SCRIPT language="javascript"> function downloadLibrary () { var libraryName = document.downloads.libraryName.value; if (libraryName != null && libraryName.length>0) { document.downloads.action = "ftp://ftp.pantherdb.org//" + libraryName; document.downloads.submit(); } } function downloadPathway () { var fileName = document.downloads.pathwayFile.value; if (fileName != null && fileName.length>0) { document.downloads.action = "downloadFile.jsp?type=pathway&fileName=" + fileName; document.downloads.submit(); } } </script> <div id="mainBody"> <div style="width:875px;"> <div class="header1">Downloads</div> <BR> <form name="downloads" method="post" action="downloadFile.jsp" target="_top"> <span class="mainText"> Browse the PANTHER ftp site via browser: <a href='http://data.pantherdb.org/ftp/'> http://data.pantherdb.org/ftp/</a> or via ftp tool <a href='ftp://ftp.pantherdb.org/'>ftp://ftp.pantherdb.org/</a> <BR><BR> <ul> <li class="orange"><a href='http://data.pantherdb.org/ftp/panther_library/current_release'>PANTHER HMM library Version 19.0</a> via <a href='ftp://ftp.pantherdb.org/panther_library/current_release'>ftp</a><BR></li> Contains the PANTHER HMMs for 15683 protein family HMMs, divided into 128012 functionally distinct protein subfamily HMMs. The PANTHER HMMs are in the <a href="http://hmmer.org/" target="EXTERNAL">HMMER</a> format. There is also a version of the library available that can be used for the Coding SNP Analysis tool. <i>release date 2024-06-20</i> <BR><BR> <li class="orange"><a href="http://data.pantherdb.org/ftp/hmm_scoring/current_release">PANTHER HMM Scoring tool</a> via <a href='ftp://ftp.pantherdb.org/hmm_scoring/current_release'>ftp</a><BR></li> Download the PANTHER scoring tool, to score protein sequences against the entire PANTHER HMM library and analyze your sequences. <i>release date May 25, 2011</i> <BR><BR> <li class="orange"><a href="http://data.pantherdb.org/ftp/cSNP_analysis/current_release">PANTHER Coding SNP Analysis tool</a> via <a href="ftp://ftp.pantherdb.org/cSNP_analysis/current_release">ftp</a><BR></li> Download the PANTHER Coding SNP Analysis tool to estimate the likelihood that a particular nonsynonymous (amino-acid changing) coding SNP will cause a functional impact to the protein. <i>release date June 6, 2016</i>. The previous version of the tool is available from <a href="ftp://ftp.pantherdb.org//cSNP_analysis/1.03/">here</a>. <BR><BR> <li class="orange"><a href="http://data.pantherdb.org/ftp/generic_mapping">PANTHER Generic Mapping</a> via <a href="ftp://ftp.pantherdb.org/generic_mapping">ftp</a><BR></li> PANTHER Generic Mapping package contains the data and a script that can easily convert a gene list that is not from one of the genomes in the PANTHER database to a PANTHER Generic Mapping file so that it can be analyzed in the PANTHER system. <i>release date April 29, 2019</i>. <BR><BR> <li class="orange"><a href="http://data.pantherdb.org/ftp/downloads/GIGA/">GIGA</a> via <a href="ftp://ftp.pantherdb.org/downloads/GIGA/">ftp</a><BR></li> GIGA is an efficient tree building program that allows phylogenetic reconstruction of very large gene families and determination of orthologs on a large scale. It is used to generate trees in the PANTHER Classification System. <i>release date August 15, 2011 (version 1.4.1 updated June 2019)</i> <BR><BR> <li class="orange"> <a href='http://data.pantherdb.org/ftp/pathway/current_release'>PANTHER Pathway 3.6.8</a> via <a href='ftp://ftp.pantherdb.org/pathway/current_release'>ftp</a><BR></li> Contains 177 regulatory and metabolic pathways, each with subfamilies and protein sequences mapped to individual pathway components. All pathway diagrams are available in both SBML and BioPAX level 3 format. SBML files, BioPAX files and Protein Sequence Association data are available for download. <BR><BR> <li class="orange"><a href='http://data.pantherdb.org/ftp/sequence_classifications/current_release'>PANTHER sequence classification files</a> via <a href='ftp://ftp.pantherdb.org/sequence_classifications/current_release'>ftp</a><BR></li> Contains the PANTHER family, subfamily, molecular function, biological process, and pathway classifications for the the complete proteomes derived from the human, mouse, rat and Drosophila melanogaster genomes, as well as the classifications of all proteins in the UniProt dataset.<BR><BR> <li class="orange"><a href='http://data.pantherdb.org/ftp/hmm_classifications/current_release'>PANTHER HMM Classification file</a> via <a href='ftp://ftp.pantherdb.org/hmm_classifications/current_release'>ftp</a><BR></li> Contains the PANTHER family/subfamily name, and the molecular function, biological process, and pathway classifications for every PANTHER protein family and subfamily in PANTHER HMM library Version 19.0.<BR><BR> <li class="orange"><a target="_blank" href="http://paintcuration.usc.edu/downloads/paintApp.tar">PAINT</a><BR></li> PAINT is a java application for viewing tree files. Minimum Java version 1.8 required. To install, uncompress the download file and execute launchTAV.bat for windows or sh launchTAV.sh for MAC.<BR><BR> <li class="orange"><a target="_blank" href="http://www.celldesigner.org/">CellDesigner™</a><BR></li> CellDesigner™ is a software program for drawing pathway networks and capture molecular events using controlled graphic notations. The diagrams generated by Cell Designer are stored in SBML (Systems Biology Markup Language) format, and can be shared by other software that supports the same standard. </ul> </form> </span> <!-- End Main Content --> </div> <!--</td></tr></table>--> <!-- Page Footer begins here --> <div id="footer"> <table width="915" cellpadding="0" cellspacing="0" border="0" width="100%"> <tr> <td align="center"> <span class="legal"> <DIV style=" padding: 0px 5px 0px 5px;text-align:center;vertical-align:middle;"> <a href="/about.jsp">About</a> | <a href="/releaseInfo.jsp">Release Information</a> | <a href="/feedback.jsp">Contact Us</a> | <a href="/systemRequirements.jsp">System Requirements</a> | <a href="/terms/privacyPolicy.jsp">Privacy Policy</a> | <a href="/terms/disclaimer.jsp">Disclaimer</a> <a href="http://geneontology.org/" target="_top"><img src="/images/logos/go-logo.mini.png" border=0 style="padding: 0px 5px 0px 5px;vertical-align: middle;border:0px"></a> <a href="https://globalbiodata.org/scientific-activities/global-core-biodata-resources" target="_top"><img src="/images/logos/GCBR-Logo-RGB.svg" border=0 width="94px" height="40px" style="vertical-align: middle;border:0px"></a> </DIV> </span> </td> </TR> <TR> <td align="center"> <span class="legal"> © Copyright 2024 Paul Thomas All Rights Reserved.</span> </td> </TR> </table> <br> <!-- Page Footer ends here --> </td></tr></table> <script language="JavaScript" type="text/javascript"> if (null === window.name || undefined === window.name) { window.name="panthermain"; } </script> <script language="JavaScript" type="text/javascript" src="/js/popout_window.js"></script> <script language="JavaScript" type="text/javascript" src="/js/cookie.js"></script> <script language="JavaScript" type="text/javascript" src="/js/pubPantherCommon.js"></script> <script language="JavaScript" type="text/javascript" src="/js/pathway.js"></script> <script language="JavaScript" type="text/javascript" src="/js/quicksearch.js"></script> <script language="JavaScript" type="text/javascript" src="/js/registration.js"></script> <script language="JavaScript" type="text/javascript" src="/js/subscription.js"></script> </div> <!-- footer div--> </body> </html>