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href="/web/20080817225118/http://www.dcp2.org/page/main/MyDCPP.html">My DCPP</a></dt></dl> </div> </div> <div class="main"> <div class="pagegeader"> <div class="breadcrumbs"> <p><a id="bc_nav_home" href="/web/20080817225118/http://www.dcp2.org/">Home</a>  >  <a href="/web/20080817225118/http://www.dcp2.org/page/main/ViewPublications.html" id="bc_nav_publications"> Publications</a>  >  </p> </div> <h1 id="pagetitle">Global Burden of Disease and Risk Factors</h1> </div> <div class="leftcol"> <div class="leftblock"> <div class="contentblock"> <p> <p>This book emerges from two separate, but intersecting, strands of work that began in the late 1980s, when the World Bank initiated a review of priorities for the control of specific diseases. The review generated findings about the comparative cost-effectiveness of interventions for most diseases important in developing countries. The purpose of the cost-effectiveness analysis (CEA) was to inform decision making within the health sectors of highly resource-constrained countries. This process resulted in the publication of the first edition of <em>Disease Control Priorities in Developing Countries (DCP1)</em>.</p> <p>Also important for informing policy is a consistent, quantitative assessment of the relative magnitudes of diseases, injuries, and their risk factors. <em>DCP1</em> included an initial assessment of health status for low- and middle-income countries as measured by deaths from specific causes; importantly, the numbers of cause-specific deaths for each age-sex group were constrained by the total number of deaths as estimated by demographers. This consistency constraint led to downward revision of the estimates of deaths from many diseases.</p> <p>These two strands of work—CEA and burden of disease—were further developed during preparation of the <a href="https://web.archive.org/web/20080817225118/http://files.dcp2.org/pdf/WorldDevelopmentReport1993.pdf"><em>World Development Report 1993: Investing in Health</em></a>. This report drew on both the CEA work in DCP1 and on a growing academic literature on CEA. In addition, the World Bank invested in generating improved estimates of deaths and the disease burden by age, cause, and region for 1990.</p> <p>Over the past six years, the World Health Organization has undertaken a new assessment of the global burden of disease for 2000-2. The World Health Organization has also invested in improving the conceptual, methodological, and empirical basis of burden of disease assessments and the assessment of the disease and injury burden from major risk factors. During 1999-2004, the authors of this volume and many collaborators from around the world worked intensively to assemble an updated, comprehensive assessment of the global burden of disease and its causes.</p> <p>The <em>Global Burden of Disease and Risk Factors</em> is the definitive, scientific account of these efforts and of the health conditions of the world's population at the beginning of the 21st century. This book includes a full account of methods, the complete results of recent work, and an assessment of trends for total mortality and for major causes of death among children under five. In addition, two chapters cover sensitivity and uncertainty analyses in relation to a broad range of potentially important parameters.</p> </p> </div> </div> <div class="leftblock twocol"> <div class="left_col"> <div class="bookcover"> <img src="/web/20080817225118im_/http://www.dcp2.org/images/GlobalBurden_170.jpg" alt="Global Burden of Disease and Risk Factors" title="Global Burden of Disease and Risk Factors"/> </div> <div class="left_col_block color"> <h3> Book Info </h3> <div class="contentblock"> <p class="normal"> <a href="/web/20080817225118/http://www.dcp2.org/main/EditorsAndAuthors.html"> Editors and Authors</a> <br/> Pages: 552<br/> Published: April 2006<br/> ISBN: 0-8213-6262-3<br/> <ul class="normal"> <li> <a href="https://web.archive.org/web/20080817225118/http://files.dcp2.org/pdf/GBD/GBD.pdf"> Download PDF Version </a> </li> <li> <a href="https://web.archive.org/web/20080817225118/http://publications.worldbank.org/ecommerce/catalog/product?item_id=4856077" target="_blank" id="link_purchase"> Purchase Book </a> </ul> </div> </div> <div class="left_col_block color" id="customBookBox"> <h3>CUSTOM BOOKS</h3> <div class="contentblock"> <p>Select, organize, download, and save your choice of chapters into a single PDF file for printing and distribution. This is a free service.</p> <p> <a href="/web/20080817225118/http://www.dcp2.org/page/main/MyDCPP.html" id="link_custombook">My DCPP</a><br/> Log in to view your saved custom books </p> </div> </div> </div> <div class="right_col"> <div class="contentblock"> <h2>Chapters </h2> <ol id="chapters" class="chapters"> <li id="chapter_612"> Front Matter <br/> <a href="https://web.archive.org/web/20080817225118/http://files.dcp2.org/pdf/GBD/GBDFM.pdf" target="_blank"> Download PDF</a>   <a href="/web/20080817225118/http://www.dcp2.org/pubs/GBD/0/FullText" id="link_sections_0"> Full Text</a> </li><li id="chapter_613"> 1. Measuring the Global Burden of Disease and Risk Factors, 1990—2001 <br/> <a href="/web/20080817225118/http://www.dcp2.org/pubs/GBD/1/" id="link_chapter_613"> Abstract</a>    <a href="https://web.archive.org/web/20080817225118/http://files.dcp2.org/pdf/GBD/GBD01.pdf" target="_blank"> Download PDF</a>   <a href="/web/20080817225118/http://www.dcp2.org/pubs/GBD/1/FullText" id="link_sections_1"> Full Text</a> </li><li id="chapter_614"> 2. Demographic and Epidemiological Characteristics of Major Regions, 1990—2001 <br/> <a href="/web/20080817225118/http://www.dcp2.org/pubs/GBD/2/" id="link_chapter_614"> Abstract</a>    <a href="https://web.archive.org/web/20080817225118/http://files.dcp2.org/pdf/GBD/GBD02.pdf" target="_blank"> Download PDF</a>   <a href="/web/20080817225118/http://www.dcp2.org/pubs/GBD/2/FullText" id="link_sections_2"> Full Text</a> </li><li id="chapter_615"> 3. The Burden of Disease and Mortality by Condition: Data, Methods, and Results for 2001 <br/> <a href="/web/20080817225118/http://www.dcp2.org/pubs/GBD/3/" id="link_chapter_615"> Abstract</a>    <a href="https://web.archive.org/web/20080817225118/http://files.dcp2.org/pdf/GBD/GBD03.pdf" target="_blank"> Download PDF</a>   <a href="/web/20080817225118/http://www.dcp2.org/pubs/GBD/3/FullText" id="link_sections_3"> Full Text</a> </li><li id="chapter_616"> 4. Comparative Quantification of Mortality and Burden of Disease Attributable to Selected Risk Factors <br/> <a href="/web/20080817225118/http://www.dcp2.org/pubs/GBD/4/" id="link_chapter_616"> Abstract</a>    <a href="https://web.archive.org/web/20080817225118/http://files.dcp2.org/pdf/GBD/GBD04.pdf" target="_blank"> Download PDF</a>   <a href="/web/20080817225118/http://www.dcp2.org/pubs/GBD/4/FullText" id="link_sections_4"> Full Text</a> </li><li id="chapter_617"> 5. Sensitivity and Uncertainty Analyses for Burden of Disease and Risk Factor Estimates <br/> <a href="/web/20080817225118/http://www.dcp2.org/pubs/GBD/5/" id="link_chapter_617"> Abstract</a>    <a href="https://web.archive.org/web/20080817225118/http://files.dcp2.org/pdf/GBD/GBD05.pdf" target="_blank"> Download PDF</a>   <a href="/web/20080817225118/http://www.dcp2.org/pubs/GBD/5/FullText" id="link_sections_5"> Full Text</a> </li><li id="chapter_627"> 6. Incorporating Deaths Near the Time of Birth into Estimates of the Global Burden of Disease <br/> <a href="/web/20080817225118/http://www.dcp2.org/pubs/GBD/6/" id="link_chapter_627"> Abstract</a>    <a href="https://web.archive.org/web/20080817225118/http://files.dcp2.org/pdf/GBD/GBD06.pdf" target="_blank"> Download PDF</a>   <a href="/web/20080817225118/http://www.dcp2.org/pubs/GBD/6/FullText" id="link_sections_6"> Full Text</a> </li><li id="chapter_629"> Glossary <br/> <a href="https://web.archive.org/web/20080817225118/http://files.dcp2.org/pdf/GBD/GBDglossary.pdf" target="_blank"> Download PDF</a>   <a href="/web/20080817225118/http://www.dcp2.org/pubs/GBD/7/FullText" id="link_sections_7"> Full Text</a> </li><li id="chapter_630"> Index <br/> <a href="https://web.archive.org/web/20080817225118/http://files.dcp2.org/pdf/GBD/GBDindex.pdf" target="_blank"> Download PDF</a>   </li> </ol> </div> </div> </div> </div> <div class="rightcol"> <div class="rightblock"> <h2>QUICK FIND</h2> <div class="contentblock"> <p>Find specific content in the three core DCPP publications.</p> <form method="post" action="/web/20080817225118/http://www.dcp2.org/direct/_/main/ViewBook,$QuickFind.quickFind.html" name="quickFind" id="quickFind" class="quickfind"> <div style="display:none;"><input type="hidden" name="formids" value="countrySelect,diseaseSelect,topicSelect,go"/> <input type="hidden" name="submitmode" value=""/> <input type="hidden" name="submitname" value=""/> </div> <fieldset> <select name="countrySelect" id="countrySelect"> <option value="0" selected="selected">Region / Country</option> <option value="1">East Asia and Pacific</option> <option value="2">--American Samoa</option> <option value="3">--Cambodia</option> <option value="16">--China</option> <option value="4">--Fiji</option> <option value="5">--Indonesia</option> <option value="6">--Kiribati</option> <option value="7">--Korea, Democratic Republic</option> <option value="8">--Lao PDR</option> <option value="9">--Malaysia</option> <option value="10">--Marshall Islands</option> <option value="11">--Micronesia, Federated States</option> <option value="12">--Mongolia</option> <option value="13">--Myanmar</option> <option value="14">--Northern Mariana Islands</option> <option value="217">--Palau</option> <option value="15">--Papua New Guinea</option> <option value="218">--Philippines</option> <option value="17">--Samoa</option> <option value="18">--Solomon Islands</option> <option value="215">--Thailand</option> <option value="19">--Timor-Leste</option> <option value="20">--Tonga</option> <option value="21">--Vanuatu</option> <option value="22">--Vietnam</option> <option value="23">Europe and Central Asia</option> <option value="24">--Albania</option> <option value="25">--Armenia</option> <option value="26">--Azerbaijan</option> <option value="27">--Belarus</option> <option value="28">--Bosnia and Herzegovina</option> <option value="29">--Bulgaria</option> <option value="30">--Croatia</option> <option value="31">--Czech Republic</option> <option value="32">--Estonia</option> <option value="33">--Georgia</option> <option value="34">--Hungary</option> <option value="35">--Kazakhstan</option> <option value="36">--Kyrgyz Republic</option> <option value="37">--Latvia</option> <option value="38">--Lithuania</option> <option value="39">--Macedonia, FYR</option> <option value="40">--Moldova</option> <option value="41">--Poland</option> <option value="42">--Romania</option> <option value="43">--Russian Federation</option> <option value="44">--Serbia and Montenegro</option> <option value="45">--Slovak Republic</option> <option value="46">--Tajikistan</option> <option value="47">--Turkey</option> <option value="48">--Turkmenistan</option> <option value="49">--Ukraine</option> <option value="50">--Uzbekistan</option> <option value="102">High Income OECD</option> <option value="103">--Australia</option> <option value="104">--Austria</option> <option 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value="53">--Argentina</option> <option value="54">--Barbados</option> <option value="55">--Belize</option> <option value="56">--Bolivia</option> <option value="57">--Brazil</option> <option value="58">--Chile</option> <option value="59">--Colombia</option> <option value="60">--Costa Rica</option> <option value="61">--Cuba</option> <option value="62">--Dominica</option> <option value="63">--Dominican Republic</option> <option value="64">--Ecuador</option> <option value="65">--El Salvador</option> <option value="66">--Grenada</option> <option value="67">--Guatemala</option> <option value="68">--Guyana</option> <option value="69">--Haiti</option> <option value="70">--Honduras</option> <option value="71">--Jamaica</option> <option value="72">--Mexico</option> <option value="73">--Nicaragua</option> <option value="74">--Panama</option> <option value="75">--Paraguay</option> <option value="76">--Peru</option> <option value="77">--Puerto Rico</option> <option value="78">--St. Kitts and Nevis</option> <option value="79">--St. Lucia</option> <option value="80">--St. Vincent and the Grenadines</option> <option value="81">--Suriname</option> <option value="82">--Trinidad and Tobago</option> <option value="83">--Uruguay</option> <option value="84">--Venezuela, RB</option> <option value="85">Middle East and North Africa</option> <option value="86">--Algeria</option> <option value="87">--Djibouti</option> <option value="88">--Egypt, Arab Rep.</option> <option value="89">--Iran, Islamic Rep.</option> <option value="90">--Iraq</option> <option value="91">--Jordan</option> <option value="92">--Lebanon</option> <option value="93">--Libya</option> <option value="94">--Morocco</option> <option value="95">--Oman</option> <option value="97">--Saudi Arabia</option> <option value="98">--Syrian Arab Republic</option> <option value="99">--Tunisia</option> <option value="100">--West Bank and Gaza</option> <option value="101">--Yemen, Rep.</option> <option value="127">Other High Income</option> <option value="128">--Andorra</option> <option value="129">--Aruba</option> <option value="130">--Bahamas, The</option> <option value="131">--Bahrain</option> <option value="132">--Bermuda</option> <option value="133">--Brunei</option> <option value="134">--Cayman Islands</option> <option value="135">--Channel Islands</option> <option value="136">--Cyprus</option> <option value="137">--Faeroe Islands</option> <option value="138">--French Polynesia</option> <option value="139">--Greenland</option> <option value="140">--Guam</option> <option value="141">--Hong Kong, China</option> <option value="142">--Isle of Man</option> <option value="143">--Israel</option> <option value="144">--Kuwait</option> <option value="145">--Liechtenstein</option> <option value="146">--Macao, China</option> <option value="147">--Malta</option> <option value="148">--Monaco</option> <option value="149">--Netherlands Antilles</option> <option value="150">--New Caledonia</option> <option value="151">--Qatar</option> <option value="152">--San Marino</option> <option value="153">--Singapore</option> <option value="154">--Slovenia</option> <option value="155">--United Arab Emirates</option> <option value="156">--Virgin Islands (U.S)</option> <option value="157">South Asia</option> <option value="158">--Afghanistan</option> <option value="159">--Bangladesh</option> <option value="160">--Bhutan</option> <option value="161">--India</option> <option value="162">--Maldives</option> <option value="163">--Nepal</option> <option value="164">--Pakistan</option> <option value="165">--Sri Lanka</option> <option value="166">Sub-Saharan Africa</option> <option value="167">--Angola</option> <option value="168">--Benin</option> <option value="169">--Botswana</option> <option value="170">--Burkina Faso</option> <option value="171">--Burundi</option> <option value="172">--Cameroon</option> <option value="173">--Cape Verde</option> <option value="174">--Central African Republic</option> <option value="175">--Chad</option> <option value="176">--Comoros</option> <option value="177">--Congo, Dem. Rep.</option> <option value="178">--Congo, Rep</option> <option value="179">--Cote d'lvoire</option> <option value="180">--Equatorial Guinea</option> <option value="181">--Eritrea</option> <option value="182">--Ethiopia</option> <option value="183">--Gabon</option> <option value="184">--Gambia, The</option> <option value="185">--Ghana</option> <option value="186">--Guinea</option> <option value="187">--Guinea-Bissau</option> <option value="188">--Kenya</option> <option value="189">--Lesotho</option> <option value="190">--Liberia</option> <option value="191">--Madagascar</option> <option value="192">--Malawi</option> <option value="193">--Mali</option> <option value="194">--Mauritania</option> <option value="195">--Mauritius</option> <option value="196">--Mayotte</option> <option value="197">--Mozambique</option> <option value="198">--Namibia</option> <option value="199">--Niger</option> <option value="200">--Nigeria</option> <option value="201">--Rwanda</option> <option value="202">--Sao Tome and Principe</option> <option value="203">--Senegal</option> <option value="204">--Seychelles</option> <option value="205">--Sierra Leone</option> <option value="206">--Somalia</option> <option value="207">--South Africa</option> <option value="208">--Sudan</option> <option value="209">--Swaziland</option> <option value="210">--Tanzania</option> <option value="211">--Togo</option> <option value="212">--Uganda</option> <option value="213">--Zambia</option> <option value="214">--Zimbabwe</option> </select> <br/> </fieldset> <fieldset> <select name="diseaseSelect" id="diseaseSelect"> <option value="0" selected="selected">Disease / Condition</option> <option value="1">Addictions</option> <option value="2">Adolescent & Childhood Diseases</option> <option value="6">Blood-Related Diseases</option> <option value="8">Cancers</option> <option value="9">Cardiovascular Disease</option> <option value="17">Diabetes</option> <option value="18">Diarrheal Disease</option> <option value="20">Genitourinary Diseases</option> <option value="21">Hearing & Vision Loss</option> <option value="25">Helminth Infections</option> <option value="28">HIV/AIDS</option> <option value="31">Infectious Diseases</option> <option value="32">Injuries & Violence</option> <option value="37">Learning & Developmental Disabilities</option> <option value="42">Malaria</option> <option value="43">Maternal & Neonatal Conditions</option> <option value="45">Mental Disorders</option> <option value="46">Musculoskeletal Conditions</option> <option value="48">Neurological Disorders</option> <option value="49">Noncommunicable Diseases</option> <option value="50">Nutrition</option> <option value="52">Oral & Craniofacial Diseases</option> <option value="55">Respiratory Diseases</option> <option value="59">Sexually Transmitted Infections</option> <option value="60">Skin Diseases</option> <option value="66">Tropical Diseases</option> <option value="67">Tuberculosis</option> <option value="69">Vaccine-Preventable Diseases</option> <option value="71">Women's Health</option> </select> <br/> </fieldset> <fieldset> <select name="topicSelect" id="topicSelect"> <option value="0" selected="selected">Topic</option> <option value="21">Contributing and Risk Factors</option> <option value="1">Diseases and Conditions</option> <option value="47">Finance and Cost-Effectiveness</option> <option value="30">Interventions and Strategies</option> <option value="50">Policy and Systems</option> <option value="56">Special Populations</option> </select> <br/> </fieldset> <input type="submit" name="go" id="go" value="Go" class="gobutton"/> </form> </div> </div> <div class="rightblock"> <h2>EMAIL UPDATES</h2> <div class="contentblock"> <p>Sign up to receive periodic email updates from DCPP</p> <form method="post" action="/web/20080817225118/http://www.dcp2.org/direct/_/main/ViewBook,$EmailUpdates.emailUpdatesForm.html" name="emailUpdatesForm" id="emailUpdatesForm" class="signup"> <div 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href="https://web.archive.org/web/20080817225118/http://files.dcp2.org/pdf/GBD/GBDFrench1.pdf" target="_blank"> French Chapter 1</a> <br/> <span>(PDF | 0.4MB)</span> <br/> <a href="https://web.archive.org/web/20080817225118/http://files.dcp2.org/pdf/GBD/GBDSpanish1.pdf" target="_blank"> Spanish Chapter 1</a> <br/> <span>(PDF | 0.2MB)</span> <br/> </p> </div> </div> </div> <div class="clear"> </div> </div> <div class="copyright"> <div class="content"> <ul> <li><a href="/web/20080817225118/http://www.dcp2.org/page/main/About.html" id="nav_about-dcpp">About</a>  | </li> <li><a href="/web/20080817225118/http://www.dcp2.org/page/main/ContactUs.html" id="nav_contactus">Contact Us</a>  | </li> <li><a href="/web/20080817225118/http://www.dcp2.org/page/main/Sitemap.html" id="nav_sitemap">Site Map</a>  | </li> <li><a href="/web/20080817225118/http://www.dcp2.org/page/main/Privacy.html" id="nav_privacy">Privacy Policy</a>  | </li> <li><a 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