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Serum from pregnant donors induces <span class="highlight-field">human</span> beta cell proliferation. <em class='incite-journal-name' onclick='ShowInCiteJournal(12737);'>Islets</em> 2024;<b>16</b>:2334044. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38533763' target='_blank'>38533763</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10978022' target='_blank'>PMC10978022</a> DOI: <a href='https://dx.doi.org/10.1080/19382014.2024.2334044' target='_blank'>10.1080/19382014.2024.2334044</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1080/19382014.2024.2334044','38533763', 'human')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(1);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(1);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(1);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(1);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1080/19382014.2024.2334044' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(12737);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://accounts.taylorfrancis.com/identity/#/login' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 10/11/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 03/19/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 03/28/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv1" value="10.1080/19382014.2024.2334044" /> <div style="display: none" id="articleAbstract1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Pancreatic beta cells are among the slowest replicating cells in the human body and have not been observed to increase in number except during the fetal and neonatal period, in cases of obesity, during puberty, as well as during pregnancy. Pregnancy is associated with increased beta cell mass to meet heightened insulin demands. This phenomenon raises the intriguing possibility that factors present in the serum of pregnant individuals may stimulate beta cell proliferation and offer insights into expansion of the beta cell mass for treatment and prevention of diabetes. The primary objective of this study was to test the hypothesis that serum from pregnant donors contains bioactive factors capable of inducing human beta cell proliferation. An immortalized human beta cell line with protracted replication (EndoC-βH1) was cultured in media supplemented with serum from pregnant and non-pregnant female and male donors and assessed for differences in proliferation. This experiment was followed by assessment of proliferation of primary human beta cells. Sera from five out of six pregnant donors induced a significant increase in the proliferation rate of EndoC-βH1 cells. Pooled serum from the cohort of pregnant donors also increased the rate of proliferation in primary human beta cells. This study demonstrates that serum from pregnant donors stimulates human beta cell proliferation. These findings suggest the existence of pregnancy-associated factors that can offer novel avenues for beta cell regeneration and diabetes prevention strategies. Further research is warranted to elucidate the specific factors responsible for this effect. </div> <a href="javascript:ShowArticleAbstract(1);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Beta+cell%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Beta cell</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22EdU%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">EdU</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22EndoC-%ce%b2H1%2c+proliferation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">EndoC-βH1, proliferation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22diabetes%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">diabetes</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22insulin%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">insulin</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22islet%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">islet</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22pregnancy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">pregnancy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22primary%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">primary</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22serum%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">serum</a></li></ul> <a href="javascript:ShowArticleKeywords(1);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Infant%2c+Newborn%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Infant, Newborn</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pregnancy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pregnancy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Insulin%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Insulin/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Insulin-Secreting+Cells%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Insulin-Secreting Cells/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+Line%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell Line</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Diabetes+Mellitus%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Diabetes Mellitus/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+Proliferation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell Proliferation</a></li></ul> <a href="javascript:ShowArticleMeSH(1);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIDDK+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">R01 DK132387 NIDDK NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIDDK+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">UC4 DK098085 NIDDK NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NCATS+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">UL1 TR001427 NCATS NIH HHS</a></li></ul> <a href="javascript:ShowArticleGrant(1);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow2"> <td style="min-width: 40px; text-align: center;"> 2 </td> <td> <div id="citation2" class="article-citation"> <b>Zhou M</b>, Linn T, Petry SF. EndoC-βH3 pseudoislets are suitable for intraportal transplantation in diabetic mice. <em class='incite-journal-name' onclick='ShowInCiteJournal(12737);'>Islets</em> 2024;<b>16</b>:2406041. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39298538' target='_blank'>39298538</a> DOI: <a href='https://dx.doi.org/10.1080/19382014.2024.2406041' target='_blank'>10.1080/19382014.2024.2406041</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1080/19382014.2024.2406041','39298538', 'human')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(2);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(2);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(2);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1080/19382014.2024.2406041' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(12737);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://accounts.taylorfrancis.com/identity/#/login' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/28/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/30/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/15/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/22/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv2" value="10.1080/19382014.2024.2406041" /> <div style="display: none" id="articleAbstract2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">Islet or β-cell transplantation is a therapeutical approach to substitute the insulin-producing cells which are abolished in type 1 diabetes mellitus. The shortage of human islets as well as the complicated and costly isolation process limit the application of these techniques in daily clinical practice. EndoC-βH is a human β-cell line that readily forms aggregates termed pseudoislets, providing an alternative to primary human islets or β-cells. </div><div class="abstract-label">METHODS</div><div class="abstract-content">EndoC-βH3 cells were seeded and incubated to form pseudoislets. Their insulin secretion was analyzed by ELISA and compared with cell monolayers. Pseudoislets were transplanted into streptozotocin-treated NMRi nu/nu mice. Blood glucose was monitored before and after transplantation and compared with wild types. Grafts were analyzed by immunohistology. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">This study shows that EndoC-βH cells are able to form pseudoislets by aggregation, leading to an enhanced glucose stimulated insulin secretion in vitro. These pseudoislets were then successfully transplanted into the livers of diabetic mice and produced insulin in vitro. Blood glucose levels of the streptozocin-treated recipient mice were significantly decreased when compared to pre-transplantation and matched the levels found in control mice. </div><div class="abstract-label">CONCLUSION</div><div class="abstract-content">We suggest pseudoislets aggregated from EndoC-βH cells as a valuable and promising model for islet transplantation research. </div> <a href="javascript:ShowArticleAbstract(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22EndoC%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">EndoC</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human-to-mouse%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human-to-mouse</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22islet+transplantation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">islet transplantation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22pseudoislets%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">pseudoislets</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22streptozotocin%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">streptozotocin</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22type+1+diabetes+mellitus%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">type 1 diabetes mellitus</a></li></ul> <a href="javascript:ShowArticleKeywords(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Diabetes+Mellitus%2c+Experimental%2ftherapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Diabetes Mellitus, Experimental/therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Islets+of+Langerhans+Transplantation%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Islets of Langerhans Transplantation/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Insulin-Secreting+Cells%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Insulin-Secreting Cells/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Insulin%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Insulin/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Blood+Glucose%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Blood Glucose/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Insulin+Secretion%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Insulin Secretion</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+Line%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell Line</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%2c+Nude%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice, Nude</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+Aggregation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell Aggregation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Diabetes+Mellitus%2c+Type+1%2ftherapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Diabetes Mellitus, Type 1/therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Diabetes+Mellitus%2c+Type+1%2fsurgery%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Diabetes Mellitus, Type 1/surgery</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Diabetes+Mellitus%2c+Type+1%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Diabetes Mellitus, Type 1/metabolism</a></li></ul> <a href="javascript:ShowArticleMeSH(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(2);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow3"> <td style="min-width: 40px; text-align: center;"> 3 </td> <td> <div id="citation3" class="article-citation"> <b>Andrews PW</b>. Germ cell tumors, cell surface markers, and the early search for <span class="highlight-field">human</span> pluripotent stem cells. <em class='incite-journal-name' onclick='ShowInCiteJournal(3460);'>Bioessays</em> 2024;<b>46</b>:e2400094. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39115324' target='_blank'>39115324</a> DOI: <a href='https://dx.doi.org/10.1002/bies.202400094' target='_blank'>10.1002/bies.202400094</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1002/bies.202400094','39115324', 'human')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(3);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(3);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(3);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(3);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1002/bies.202400094' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3460);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 04/17/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 07/27/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 07/31/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/27/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv3" value="10.1002/bies.202400094" /> <div style="display: none" id="articleAbstract3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Many strands of research by different groups, starting from teratocarcinomas in the laboratory mouse, later moving the corresponding human tumors, contributed to the isolation and description of human pluripotent stem cells (PSCs). In this review, I highlight the contributions from my own research, particularly at the Wistar Institute during the 1980s, when with my colleagues we characterized one of the first clonal lines of pluripotent human embryonal carcinoma (EC) cells, the stem cells of teratocarcinomas, and identified key features including cell surface antigen markers that have since found a place in the study and exploitation of human PSC. Much of this research depended upon close teamwork with colleagues, many in other laboratories, who contributed different expertise and experience. It was also often driven by circumstance and chance rather than pursuit of a grand design. </div> <a href="javascript:ShowArticleAbstract(3);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22cell+surface+antigens%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">cell surface antigens</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22embryonal+carcinoma+cell%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">embryonal carcinoma cell</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22pluripotent+stem+cell%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">pluripotent stem cell</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22teratocarcinoma%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">teratocarcinoma</a></li></ul> <a href="javascript:ShowArticleKeywords(3);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pluripotent+Stem+Cells%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pluripotent Stem Cells/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pluripotent+Stem+Cells%2fcytology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pluripotent Stem Cells/cytology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neoplasms%2c+Germ+Cell+and+Embryonal%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neoplasms, Germ Cell and Embryonal/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neoplasms%2c+Germ+Cell+and+Embryonal%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neoplasms, Germ Cell and Embryonal/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Biomarkers%2c+Tumor%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Biomarkers, Tumor/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Antigens%2c+Surface%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Antigens, Surface/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Teratocarcinoma%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Teratocarcinoma/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Teratocarcinoma%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Teratocarcinoma/metabolism</a></li></ul> <a href="javascript:ShowArticleMeSH(3);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Medical+Research+Council%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">MR/V002163/1 Medical Research Council</a></li></ul> <a href="javascript:ShowArticleGrant(3);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow4"> <td style="min-width: 40px; text-align: center;"> 4 </td> <td> <div id="citation4" class="article-citation"> <b>Dong D</b>, Hosomi K, Shimizu T, Okada KI, Kadono Y, Mori N, Hori Y, Yahata N, Hirabayashi T, Kishima H, Saitoh Y. Cross-Species Convergence of Functional Connectivity Changes in Thalamic Pain Across <span class="highlight-field">Human</span> Patients and Model Macaques. <em>THE JOURNAL OF PAIN</em> 2024;<b>25</b>:104661. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39182537' target='_blank'>39182537</a> DOI: <a href='https://dx.doi.org/10.1016/j.jpain.2024.104661' target='_blank'>10.1016/j.jpain.2024.104661</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.jpain.2024.104661','39182537', 'human')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(4);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(4);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(4);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.jpain.2024.104661' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 01/04/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/12/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/19/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 08/27/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv4" value="10.1016/j.jpain.2024.104661" /> <div style="display: none" id="articleAbstract4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Thalamic pain can be understood as a network reorganization disorder. This study aimed to investigate functional connectivity (FC) in human patients and a macaque model of thalamic pain. In humans, resting-state FC was compared between patients with thalamic pain and healthy individuals. Furthermore, resting-state FC was compared in macaques, before and after the induction of thalamic pain in the same individuals. FC between the amygdala of the unaffected hemisphere and the brainstem was significantly higher in patients with thalamic pain. More specifically, a significantly higher FC was observed between the basolateral amygdala and the ventral tegmental area, which also significantly predicted the value of a visual analog scale of pain intensity in individual patients. The macaque model of thalamic pain also exhibited a significantly higher FC between the amygdala of the unaffected hemisphere and the brainstem, particularly between the basolateral amygdala and the midbrain. Furthermore, the previously reported significantly higher FC between the amygdala and the mediodorsal nucleus of the thalamus in macaques with thalamic pain was also reproduced in the human patients. Therefore, the present results suggest that the FC changes in the regions associated with emotion, memory, motivation, and reward are part of the underlying mechanisms of thalamic pain onset present in both human patients and model macaques. This cross-species convergence provides new insights into the neurological mechanisms underlying thalamic pain, paving the way for further studies and the development of therapeutic strategies. PERSPECTIVE: This article presents that the FC changes in the regions associated with emotion, motivation, and reward are part of the underlying mechanisms of thalamic pain in humans and macaques. </div> <a href="javascript:ShowArticleAbstract(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cross-species%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cross-species</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22functional+connectivity+changes%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">functional connectivity changes</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22macaques%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">macaques</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22thalamic+pain%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">thalamic pain</a></li></ul> <a href="javascript:ShowArticleKeywords(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Magnetic+Resonance+Imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Magnetic Resonance Imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Middle+Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Middle Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neural+Pathways%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neural Pathways/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neural+Pathways%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neural Pathways/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Thalamus%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Thalamus/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Thalamus%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Thalamus/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Disease+Models%2c+Animal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Disease Models, Animal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Amygdala%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Amygdala/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Amygdala%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Amygdala/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Species+Specificity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Species Specificity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Stem%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Stem/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Stem%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Stem/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Young+Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Young Adult</a></li></ul> <a href="javascript:ShowArticleMeSH(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(4);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow5"> <td style="min-width: 40px; text-align: center;"> 5 </td> <td> <div id="citation5" class="article-citation"> <b>Chinchanikar SS</b>, Fraga GR. Ancillary immunohistochemistry testing for loss of p16 in melanoma: A systematic review and meta-analysis of diagnostic accuracy studies. <em class='incite-journal-name' onclick='ShowInCiteJournal(13498);'>J Cutan Pathol</em> 2024;<b>51</b>:971-979. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39256963' target='_blank'>39256963</a> DOI: <a href='https://dx.doi.org/10.1111/cup.14717' target='_blank'>10.1111/cup.14717</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1111/cup.14717','39256963', 'human')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(5);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(5);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(5);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1111/cup.14717' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(13498);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/06/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/18/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/26/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/12/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv5" value="10.1111/cup.14717" /> <div style="display: none" id="articleAbstract5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">Ancillary immunohistochemistry testing for p16 loss has been proposed as a diagnostic tool for melanoma, but its accuracy remains uncertain. </div><div class="abstract-label">METHODS</div><div class="abstract-content">A systematic review and meta-analysis were conducted on 26 studies involving 979 melanomas and 974 nevi. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">Through bivariate analysis of data across all cut-off values, the sensitivity and specificity were calculated to be 0.55 (95% confidence interval [CI]: 0.38, 0.70) and 0.85 (95% CI: 0.70, 0.94), respectively. Summary estimates of diagnostic accuracy fell below recommended thresholds for effective tests, but subgroup analysis suggested that p16 loss could aid in diagnosing ambiguous lesions as melanoma in certain scenarios. However, the presence of p16 expression in these contexts does not definitively rule out melanoma. The findings were limited by underpowered exploratory study designs at risk for bias in patient selection and test interpretation. </div><div class="abstract-label">CONCLUSIONS</div><div class="abstract-content">While the use of p16 immunohistochemistry for detecting melanoma is not universally reliable, it may serve as a confirmatory test in differential diagnoses involving common, congenital, acral, Spitz, and deep penetrating nevi. Nevertheless, further studies are needed to validate its utility. Until then, the application of p16 immunohistochemistry in melanoma diagnosis should be regarded as experimental. </div> <a href="javascript:ShowArticleAbstract(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22diagnostic+accuracy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">diagnostic accuracy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22immunohistochemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">immunohistochemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22melanoma%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">melanoma</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22p16+protein%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">p16 protein</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22sensitivity+and+specificity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">sensitivity and specificity</a></li></ul> <a href="javascript:ShowArticleKeywords(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Biomarkers%2c+Tumor%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Biomarkers, Tumor/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Biomarkers%2c+Tumor%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Biomarkers, Tumor/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cyclin-Dependent+Kinase+Inhibitor+p16%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cyclin-Dependent Kinase Inhibitor p16/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cyclin-Dependent+Kinase+Inhibitor+p16%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cyclin-Dependent Kinase Inhibitor p16/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Diagnosis%2c+Differential%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Diagnosis, Differential</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Immunohistochemistry%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Immunohistochemistry/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Melanoma%2fdiagnosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Melanoma/diagnosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Melanoma%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Melanoma/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Melanoma%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Melanoma/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sensitivity+and+Specificity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sensitivity and Specificity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Skin+Neoplasms%2fdiagnosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Skin Neoplasms/diagnosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Skin+Neoplasms%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Skin Neoplasms/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Skin+Neoplasms%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Skin Neoplasms/pathology</a></li></ul> <a href="javascript:ShowArticleMeSH(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(5);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow6"> <td style="min-width: 40px; text-align: center;"> 6 </td> <td> <div id="citation6" class="article-citation"> <b>van Vliet MM</b>, Schoenmakers S, Gribnau J, Steegers-Theunissen RP. The one-carbon metabolism as an underlying pathway for placental DNA methylation - a systematic review. <em class='incite-journal-name' onclick='ShowInCiteJournal(8558);'>Epigenetics</em> 2024;<b>19</b>:2318516. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38484284' target='_blank'>38484284</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10950272' target='_blank'>PMC10950272</a> DOI: <a href='https://dx.doi.org/10.1080/15592294.2024.2318516' target='_blank'>10.1080/15592294.2024.2318516</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1080/15592294.2024.2318516','38484284', 'human')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(6);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(6);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(6);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1080/15592294.2024.2318516' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(8558);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 10/25/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 02/07/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 03/19/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv6" value="10.1080/15592294.2024.2318516" /> <div style="display: none" id="articleAbstract6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Epigenetic modifications, including DNA methylation, are proposed mechanisms explaining the impact of parental exposures to foetal development and lifelong health. Micronutrients including folate, choline, and vitamin B12 provide methyl groups for the one-carbon metabolism and subsequent DNA methylation processes. Placental DNA methylation changes in response to one-carbon moieties hold potential targets to improve obstetrical care. We conducted a systematic review on the associations between one-carbon metabolism and human placental DNA methylation. We included 22 studies. Findings from clinical studies with minimal ErasmusAGE quality score 5/10 (n = 15) and in vitro studies (n = 3) are summarized for different one-carbon moieties. Next, results are discussed per study approach: (1) global DNA methylation (n = 9), (2) genome-wide analyses (n = 4), and (3) gene specific (n = 14). Generally, one-carbon moieties were not associated with global methylation, although conflicting outcomes were reported specifically for choline. Using genome-wide approaches, few differentially methylated sites associated with S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), or dietary patterns. Most studies taking a gene-specific approach indicated site-specific relationships depending on studied moiety and genomic region, specifically in genes involved in growth and development including LEP, NR3C1, CRH, and PlGF; however, overlap between studies was low. Therefore, we recommend to further investigate the impact of an optimized one-carbon metabolism on DNA methylation and lifelong health. </div> <a href="javascript:ShowArticleAbstract(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22DoHAD%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">DoHAD</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22epigenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">epigenetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22nutrition%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">nutrition</a></li></ul> <a href="javascript:ShowArticleKeywords(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pregnancy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pregnancy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22DNA+Methylation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">DNA Methylation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Placenta%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Placenta/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Genome-Wide+Association+Study%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Genome-Wide Association Study</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Folic+Acid%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Folic Acid</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22S-Adenosylmethionine%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">S-Adenosylmethionine/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Choline%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Choline/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon/metabolism</a></li></ul> <a href="javascript:ShowArticleMeSH(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(6);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow7"> <td style="min-width: 40px; text-align: center;"> 7 </td> <td> <div id="citation7" class="article-citation"> <b>Berner J</b>, Jore S, Abass K, Rautio A. One health in the Arctic - connections and actions. <em class='incite-journal-name' onclick='ShowInCiteJournal(11493);'>Int J Circumpolar Health</em> 2024;<b>83</b>:2361544. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38870398' target='_blank'>38870398</a> DOI: <a href='https://dx.doi.org/10.1080/22423982.2024.2361544' target='_blank'>10.1080/22423982.2024.2361544</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1080/22423982.2024.2361544','38870398', 'human')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(7);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(7);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(7);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1080/22423982.2024.2361544' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(11493);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 02/12/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 05/25/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 06/15/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv7" value="10.1080/22423982.2024.2361544" /> <div style="display: none" id="articleAbstract7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">There is growing awareness and recognition of the importance of the One Health paradigm to address existing environmental threats and recognise emerging ones at an early stage among Arctic residents, public health agencies, and wildlife resource managers. The One Health approach, emphasising the interconnectedness of human, animal, and ecosystem health, plays a pivotal role in addressing these multifaceted issues. Warming climate and permafrost thaw may influence both contaminant exposure and the spread of zoonotic infectious diseases and have impacts on water and food security. Migration from rural regions to larger communities and urban centres along with increased tourism may be accompanied by changes in exposure to contaminants and zoonotic diseases. Universities have developed educational programmes and research projects on One Health in the Arctic, and under the Arctic Council there is running a project of One Arctic, One Health. These arctivities have produced interdisciplinary information and practical solutions for local communities, decision-makers, and in scientific forums. There is a need for epidemiological zoonotic/human disease models, as well as new approaches to integrate existing and future surveillance data to climatic and environmental data. This requires not only regional and international collaboration but also multi-agency and transdisciplinary research. </div> <a href="javascript:ShowArticleAbstract(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Zoonoses%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Zoonoses</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22infectious+diseases%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">infectious diseases</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22monitoring%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">monitoring</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22risk+assessment%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">risk assessment</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22wildlife%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">wildlife</a></li></ul> <a href="javascript:ShowArticleKeywords(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Arctic+Regions%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Arctic Regions</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22One+Health%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">One Health</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Zoonoses%2fepidemiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Zoonoses/epidemiology</a></li></ul> <a href="javascript:ShowArticleMeSH(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(7);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow8"> <td style="min-width: 40px; text-align: center;"> 8 </td> <td> <div id="citation8" class="article-citation"> <b>Bhattacharjee A</b>, Antony H, Schwarz C. <span class="highlight-field">Human</span> tactile discrimination of pulse shape is possible without preadaptation. <em class='incite-journal-name' onclick='ShowInCiteJournal(14658);'>J Neurophysiol</em> 2024;<b>132</b>:1747-1755. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39503582' target='_blank'>39503582</a> DOI: <a href='https://dx.doi.org/10.1152/jn.00376.2024' target='_blank'>10.1152/jn.00376.2024</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1152/jn.00376.2024','39503582', 'human')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(8);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(8);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(8);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(8);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1152/jn.00376.2024' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(14658);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/21/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/11/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/28/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/26/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv8" value="10.1152/jn.00376.2024" /> <div style="display: none" id="articleAbstract8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Recent progress in the field of tactile coding suggests that discrimination of texture may involve the instantaneous kinematic analysis of frictional stick-slip movements. The idea has received support from analytical psychophysical experiments employing changes of pulsatile skin deflections in a well-adapted state, i.e. when changing repetitive pulsatile stimulation from one pulse shape to another. Here we investigated whether perception of pulse shapes is possible with single, isolated pulses. In other words, whether the well-described neuronal "onset-responses" in central parts of the tactile pathway, which differ largely from "adapted responses," carry information about pulse shape. We tested human participants on a pulse shape two-alternative forced-choice discrimination paradigm: in each trial, three pulsatile skin indentations were presented at an interval of 0.5 s. Either the first or the last pulse deviated in its shape, which the participants had to correctly identify. The task could not be solved by simply integrating tactile response across the three pulses. A majority of the participants (18 out of 30) yielded a performance of P(correct) > 0.75, indicating that isolated pulse shapes reach perception. The performance was enhanced by presenting the same shape changes in the context of a preadapting series of pulses. Participants confronted with the three-pulse test did not show a systematic preference for the kinematic parameter used to change the shape. We conclude that perceptual processes in principle have access to the kinematic shape of isolated pulsatile skin deflections. However, sensory adaption plays a crucial role in the quality and specificity of encoding kinematic pulse profiles.NEW & NOTEWORTHY Can humans perceive the kinematic shape of very short tactile events? Textures impose such short events, frictional slips, which could be used for their discrimination. Using a pulse shape discrimination paradigm that enforces local analysis, we find that even the shape of isolated pulsatile skin deflections can be discriminated by humans. Providing an adaptive series of pulses, however, improves the performance, showing that the adaptive context plays an important role in instantaneous shape discrimination. </div> <a href="javascript:ShowArticleAbstract(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22adaptation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">adaptation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22fingertip%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">fingertip</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22pulsatile+stimulation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">pulsatile stimulation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22tactile+coding%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">tactile coding</a></li></ul> <a href="javascript:ShowArticleKeywords(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Touch+Perception%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Touch Perception/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Discrimination%2c+Psychological%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Discrimination, Psychological/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Touch%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Touch/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adaptation%2c+Physiological%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adaptation, Physiological/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Young+Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Young Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Biomechanical+Phenomena%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Biomechanical Phenomena</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Physical+Stimulation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Physical Stimulation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Skin%2finnervation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Skin/innervation</a></li></ul> <a href="javascript:ShowArticleMeSH(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Deutsche+Forschungsgemeinschaft+(DFG)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">SCHW577/14-2 Deutsche Forschungsgemeinschaft (DFG)</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Deutsche+Forschungsgemeinschaft+(DFG)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">SCHW577/14-3 Deutsche Forschungsgemeinschaft (DFG)</a></li></ul> <a href="javascript:ShowArticleGrant(8);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow9"> <td style="min-width: 40px; text-align: center;"> 9 </td> <td> <div id="citation9" class="article-citation"> <b>Fimognari N</b>, Kardol LR, O'Shannassy T, Sanders KA, Smith JT, Wyrwoll CS. Inclusion of genital, sexual, and gender diversity in <span class="highlight-field">human</span> reproductive teaching: impact on student experience and recommendations for tertiary educators. <em>ADVANCES IN PHYSIOLOGY EDUCATION</em> 2024;<b>48</b>:698-703. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39116390' target='_blank'>39116390</a> DOI: <a href='https://dx.doi.org/10.1152/advan.00113.2024' target='_blank'>10.1152/advan.00113.2024</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1152/advan.00113.2024','39116390', 'human')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(9);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(9);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(9);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1152/advan.00113.2024' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 07/08/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/05/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 08/10/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv9" value="10.1152/advan.00113.2024" /> <div style="display: none" id="articleAbstract9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Western societal norms have long been constrained by binary and exclusionary perspectives on matters such as infertility, contraception, sexual health, sexuality, and gender. These viewpoints have shaped research and knowledge frameworks for decades and led to an inaccurate and incomplete reproductive biology curriculum. To combat these deficiencies in reproductive systems-related education, our teaching team undertook a gradual transformation of unit content from 2018 to 2023, aiming to better reflect real diversity in human reproductive biology. This initiative involved intentional modifications, including clear use of pronoun self-identification by staff. We addressed the historical lack of representation of genital variation and helped students interrogate oversimplified reproductive biology binaries. A novel assignment was also introduced, prompting students to apply reproductive physiology knowledge to propose innovative assisted reproductive technology solutions for diverse demographics. The collective impact of these innovations had a positive effect on student learning. With improved lecture content and inclusive language, the proportion of inclusive group assignment topics chosen by students more than doubled in 2021. By 2022, coinciding with assessment topic changes, the percentage of inclusive assignments topics surpassed 50%. Further development of laboratory activities on intersex genital variation and genital modification raised further understanding of genital, sexual, gender, and cultural diversity. While implementing these changes posed challenges, pushing both staff and students out of their comfort zones at times, collaboration with relevant organizations and individuals with lived experience of queer identity proved integral. Ultimately, these relatively simple adjustments had a substantial impact on student experiences and appreciation for diversity.NEW & NOTEWORTHY We outline the teaching innovations that we have implemented to improve inclusion of diversity in reproductive biology and physiology contexts. This includes improved representation of genital, sexual, and gender diversity considerations in the curriculum. There is a critical need for these innovations as how we teach fundamentally shapes the understanding of our future medical and health professionals and researchers and thus influences the quality of future medical care and research. </div> <a href="javascript:ShowArticleAbstract(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22diversity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">diversity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22reproduction%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">reproduction</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22teaching%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">teaching</a></li></ul> <a href="javascript:ShowArticleKeywords(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Curriculum%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Curriculum</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Genitalia%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Genitalia/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Teaching%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Teaching</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sexual+Behavior%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sexual Behavior/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cultural+Diversity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cultural Diversity</a></li></ul> <a href="javascript:ShowArticleMeSH(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(9);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow10"> <td style="min-width: 40px; text-align: center;"> 10 </td> <td> <div id="citation10" class="article-citation"> <b>Khiar H</b>, Lévêque E, Lopez AG, Moreau-Grangé L, Richard L, Brunel V, Perdrix A, Takhlidjt S, Devère M, Tavolacci MP, Houivet E, Huet E, Degrimaudet B, Travers C, Leprince J, Picot M, Chartrel N, Prévost G. Serum levels of the incretin-like peptide 26RFa are diminished in women living with obesity and diabetes and restored after sleeve gastrectomy: Results from the prospective pilot RFa-Ba-S study. <em class='incite-journal-name' onclick='ShowInCiteJournal(7741);'>Diabetes Obes Metab</em> 2024;<b>26</b>:5556-5568. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39350486' target='_blank'>39350486</a> DOI: <a href='https://dx.doi.org/10.1111/dom.15871' target='_blank'>10.1111/dom.15871</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1111/dom.15871','39350486', 'human')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(10);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(10);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(10);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(10);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1111/dom.15871' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(7741);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://mc.manuscriptcentral.com/dom' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/13/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 07/28/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 07/28/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/05/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv10" value="10.1111/dom.15871" /> <div style="display: none" id="articleAbstract10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">AIM</div><div class="abstract-content">To investigate the evolution of the incretin-like peptide 26RFa in a prospective cohort of women living with obesity with or without type 2 diabetes (T2D) before and after sleeve gastrectomy (SG). </div><div class="abstract-label">METHODS</div><div class="abstract-content">In this study, a total of 61 women were divided into three groups: women living with severe obesity without T2D (WlwOB group), women living with severe obesity and T2D (WlwOB-T2D group) and lean healthy volunteers (control group). Serum 26RFa concentrations were measured using a 26RFa enzyme-linked immunosorbent assay developed specifically for this study during meal tests before SG, and 30 and 180 days after SG. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">At baseline, serum 26RFa levels were reduced in the WlwOB (P < .05) and WlwOB-T2D (P < .01) groups compared with controls. In the WlwOB-T2D group, fasting 26RFa levels were found to increase throughout the entire follow-up period up to 6 months after the SG (P < .001). During the meal tests, serum 26RFa levels increased, especially in the WlwOB-T2D group at baseline. At the end of the follow-up, the profile of 26RFa concentrations obtained during the meal test in patients with severe obesity and T2D was similar to that of the controls. </div><div class="abstract-label">CONCLUSIONS</div><div class="abstract-content">This prospective clinical study provides the first evidence that circulating 26RFa is altered mainly in WlwOB-T2D, and that these defects are partially reversed after SG. </div> <a href="javascript:ShowArticleAbstract(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%2226RFa%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">26RFa</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22QRFP%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">QRFP</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22obesity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">obesity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22sleeve+gastrectomy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">sleeve gastrectomy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22type+2+diabetes%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">type 2 diabetes</a></li></ul> <a href="javascript:ShowArticleKeywords(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Diabetes+Mellitus%2c+Type+2%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Diabetes Mellitus, Type 2/blood</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Diabetes+Mellitus%2c+Type+2%2fcomplications%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Diabetes Mellitus, Type 2/complications</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Prospective+Studies%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Prospective Studies</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gastrectomy%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gastrectomy/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Middle+Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Middle Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pilot+Projects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pilot Projects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Obesity%2c+Morbid%2fsurgery%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Obesity, Morbid/surgery</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Obesity%2c+Morbid%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Obesity, Morbid/blood</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Obesity%2c+Morbid%2fcomplications%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Obesity, Morbid/complications</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Incretins%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Incretins/blood</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Weight+Loss%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Weight Loss/physiology</a></li></ul> <a href="javascript:ShowArticleMeSH(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22CHU+Rouen%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">CHU Rouen</a></li></ul> <a href="javascript:ShowArticleGrant(10);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow11"> <td style="min-width: 40px; text-align: center;"> 11 </td> <td> <div id="citation11" class="article-citation"> <b>Angaji A</b>, Owusu M, Velling C, Dick N, Weghorn D, Berg J. High-density sampling reveals volume growth in <span class="highlight-field">human</span> tumours. <em class='incite-journal-name' onclick='ShowInCiteJournal(8168);'>eLife</em> 2024;<b>13</b>:RP95338. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39587846' target='_blank'>39587846</a> DOI: <a href='https://dx.doi.org/10.7554/elife.95338' target='_blank'>10.7554/elife.95338</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.7554/elife.95338','39587846', 'human')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(11);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(11);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(11);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(11);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.7554/elife.95338' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(8168);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/27/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv11" value="10.7554/elife.95338" /> <div style="display: none" id="articleAbstract11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">In growing cell populations such as tumours, mutations can serve as markers that allow tracking the past evolution from current samples. The genomic analyses of bulk samples and samples from multiple regions have shed light on the evolutionary forces acting on tumours. However, little is known empirically on the spatio-temporal dynamics of tumour evolution. Here, we leverage published data from resected hepatocellular carcinomas, each with several hundred samples taken in two and three dimensions. Using spatial metrics of evolution, we find that tumour cells grow predominantly uniformly within the tumour volume instead of at the surface. We determine how mutations and cells are dispersed throughout the tumour and how cell death contributes to the overall tumour growth. Our methods shed light on the early evolution of tumours in vivo and can be applied to high-resolution data in the emerging field of spatial biology. </div> <a href="javascript:ShowArticleAbstract(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22cancer+biology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">cancer biology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22evolutionary+biology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">evolutionary biology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22multi-region+tumour+samples%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">multi-region tumour samples</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22spatial+genomics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">spatial genomics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22tumour+samples%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">tumour samples</a></li></ul> <a href="javascript:ShowArticleKeywords(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carcinoma%2c+Hepatocellular%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carcinoma, Hepatocellular/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carcinoma%2c+Hepatocellular%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carcinoma, Hepatocellular/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mutation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mutation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Liver+Neoplasms%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Liver Neoplasms/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Liver+Neoplasms%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Liver Neoplasms/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Tumor+Burden%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Tumor Burden</a></li></ul> <a href="javascript:ShowArticleMeSH(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Deutsche+Forschungsgemeinschaft%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">SFB1310/2 - 325931972 Deutsche Forschungsgemeinschaft</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Spanish+Ministry+of+Science+and+Innovation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">CEX2020-001049-S Spanish Ministry of Science and Innovation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22FWF+Austrian+Science+Fund%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">10.55776/J4366 FWF Austrian Science Fund</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Generalitat+de+Catalunya%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">CERCA programme Generalitat de Catalunya</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Spanish+Ministry+of+Science+and+Innovation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">MCIN/AEI /10.13039/50110001 Spanish Ministry of Science and Innovation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Spanish+Ministry+of+Science+and+Innovation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">PGC2018-100941-A-I00 Spanish Ministry of Science and Innovation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Spanish+Ministry+of+Science+and+Innovation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">PID2021-128976NB-I001033 Spanish Ministry of Science and Innovation</a></li></ul> <a href="javascript:ShowArticleGrant(11);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow12"> <td style="min-width: 40px; text-align: center;"> 12 </td> <td> <div id="citation12" class="article-citation"> <b>Jallais M</b>, Palombo M. Introducing µGUIDE for quantitative imaging via generalized uncertainty-driven inference using deep learning. <em class='incite-journal-name' onclick='ShowInCiteJournal(8168);'>eLife</em> 2024;<b>13</b>:RP101069. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39589260' target='_blank'>39589260</a> DOI: <a href='https://dx.doi.org/10.7554/elife.101069' target='_blank'>10.7554/elife.101069</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.7554/elife.101069','39589260', 'human')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(12);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(12);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(12);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(12);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.7554/elife.101069' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(8168);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/27/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv12" value="10.7554/elife.101069" /> <div style="display: none" id="articleAbstract12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">This work proposes µGUIDE: a general Bayesian framework to estimate posterior distributions of tissue microstructure parameters from any given biophysical model or signal representation, with exemplar demonstration in diffusion-weighted magnetic resonance imaging. Harnessing a new deep learning architecture for automatic signal feature selection combined with simulation-based inference and efficient sampling of the posterior distributions, µGUIDE bypasses the high computational and time cost of conventional Bayesian approaches and does not rely on acquisition constraints to define model-specific summary statistics. The obtained posterior distributions allow to highlight degeneracies present in the model definition and quantify the uncertainty and ambiguity of the estimated parameters. </div> <a href="javascript:ShowArticleAbstract(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Bayesian+inference%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Bayesian inference</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22diffusion+MRI%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">diffusion MRI</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22microstructure+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">microstructure imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22neuroscience%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">neuroscience</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22quantitative+MRI%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">quantitative MRI</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22simulation-based+inference%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">simulation-based inference</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22uncertainty+quantification%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">uncertainty quantification</a></li></ul> <a href="javascript:ShowArticleKeywords(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Deep+Learning%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Deep Learning</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Uncertainty%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Uncertainty</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Bayes+Theorem%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Bayes Theorem</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Diffusion+Magnetic+Resonance+Imaging%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Diffusion Magnetic Resonance Imaging/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Image+Processing%2c+Computer-Assisted%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Image Processing, Computer-Assisted/methods</a></li></ul> <a href="javascript:ShowArticleMeSH(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22UK+Research+and+Innovation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Future Leaders Fellowship MR/T020296/2 UK Research and Innovation</a></li></ul> <a href="javascript:ShowArticleGrant(12);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow13"> <td style="min-width: 40px; text-align: center;"> 13 </td> <td> <div id="citation13" class="article-citation"> <b>Nugent TW</b>, Zele AJ. What can the eye see with melanopsin? <em class='incite-journal-name' onclick='ShowInCiteJournal(19666);'>Proc Natl Acad Sci U S A</em> 2024;<b>121</b>:e2411151121. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39570305' target='_blank'>39570305</a> DOI: <a href='https://dx.doi.org/10.1073/pnas.2411151121' target='_blank'>10.1073/pnas.2411151121</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1073/pnas.2411151121','39570305', 'human')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(13);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(13);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(13);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(13);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1073/pnas.2411151121' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(19666);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/03/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/22/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/22/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv13" value="10.1073/pnas.2411151121" /> <div style="display: none" id="articleAbstract13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">A subpopulation of human retinal ganglion cells contains the melanopsin photopigment, allowing them to act as a fifth photoreceptor class. These ganglion cells project to the visual cortex, but to reveal its intrinsic contribution to conscious vision is technically challenging as it requires melanopsin to be separated from the responses originating in the rods and three cone classes. Using a display engineered to isolate the melanopic visual response, we show that it detects lowpass spatial (≤0.35 cycles per degree) and temporal image content (≤1 Hz) but cannot reconstruct the stimulus form necessary for object recognition. We demonstrate that a model of the spatially diffuse intrinsically-photosensitive retinal ganglion cells' sampling structure is predictive of the measured image reconstruction limits of melanopic spatial vision. Separately, we find that under five-photoreceptor silent substitution conditions, rod pathways alone can support form vision in bright lighting when typically thought to be in saturation. Form vision that is absent from melanopsin can be only perceived in mixtures of both melanopsin and rod signals because it is the rod pathway that sees the form. Our findings show that melanopsin's unique tuning to the diffuse and slow-changing elements in the world provides a stabilized reference point for vision. </div> <a href="javascript:ShowArticleAbstract(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22ipRGCs%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">ipRGCs</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22melanopsin%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">melanopsin</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22silent+substitution%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">silent substitution</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22vision%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">vision</a></li></ul> <a href="javascript:ShowArticleKeywords(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rod+Opsins%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rod Opsins/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Retinal+Ganglion+Cells%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Retinal Ganglion Cells/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Retinal+Ganglion+Cells%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Retinal Ganglion Cells/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Vision%2c+Ocular%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Vision, Ocular/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Photic+Stimulation%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Photic Stimulation/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Retinal+Rod+Photoreceptor+Cells%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Retinal Rod Photoreceptor Cells/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Retinal+Rod+Photoreceptor+Cells%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Retinal Rod Photoreceptor Cells/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Retinal+Cone+Photoreceptor+Cells%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Retinal Cone Photoreceptor Cells/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Retinal+Cone+Photoreceptor+Cells%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Retinal Cone Photoreceptor Cells/physiology</a></li></ul> <a href="javascript:ShowArticleMeSH(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Department+of+Education+and+Training+%7c+Australian+Research+Council+(ARC)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">ARC-FT180100458 Department of Education and Training | Australian Research Council (ARC)</a></li></ul> <a href="javascript:ShowArticleGrant(13);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow14"> <td style="min-width: 40px; text-align: center;"> 14 </td> <td> <div id="citation14" class="article-citation"> <b>Yegian AK</b>, Heymsfield SB, Castillo ER, Müller MJ, Redman LM, Lieberman DE. Metabolic scaling, energy allocation tradeoffs, and the evolution of <span class="highlight-field">human</span>s' unique metabolism. <em class='incite-journal-name' onclick='ShowInCiteJournal(19666);'>Proc Natl Acad Sci U S A</em> 2024;<b>121</b>:e2409674121. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39556743' target='_blank'>39556743</a> DOI: <a href='https://dx.doi.org/10.1073/pnas.2409674121' target='_blank'>10.1073/pnas.2409674121</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1073/pnas.2409674121','39556743', 'human')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(14);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(14);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(14);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(14);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1073/pnas.2409674121' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(19666);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/16/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/11/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/20/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv14" value="10.1073/pnas.2409674121" /> <div style="display: none" id="articleAbstract14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">All organisms use limited energy to grow, survive, and reproduce, necessitating energy allocation tradeoffs, but there is debate over how selection impacted metabolic budgets and tradeoffs in primates, including humans. Here, we develop a method to compare metabolic rates as quotients of observed relative to expected values for mammals corrected for size, body composition, environmental temperature, and phylogenetic relatedness. Contrary to previous analyses, these quotients reveal that nonhuman primates have total metabolic rates expected for similar-sized mammals in similar environments. In addition, data from several small-scale societies show that humans evolved exceptionally high resting, activity, and total metabolic rates apparently by overcoming tradeoffs between resting and active energy expenditures that constrain other primates. Enhanced metabolic rates help humans fuel expanded brains, faster reproductive rates, extended longevity, and high percentage of body fat. </div> <a href="javascript:ShowArticleAbstract(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22evolution%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">evolution</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22metabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22primate%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">primate</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22tradeoffs%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">tradeoffs</a></li></ul> <a href="javascript:ShowArticleKeywords(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Energy+Metabolism%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Energy Metabolism/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Biological+Evolution%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Biological Evolution</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Basal+Metabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Basal Metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Primates%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Primates</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Phylogeny%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Phylogeny</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Body+Composition%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Body Composition</a></li></ul> <a href="javascript:ShowArticleMeSH(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22HHS+%7c+NIH+%7c+NIDDK+%7c+Division+of+Diabetes%2c+Endocrinology%2c+and+Metabolic+Diseases+(DEM)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">5P30DK072476 HHS | NIH | NIDDK | Division of Diabetes, Endocrinology, and Metabolic Diseases (DEM)</a></li></ul> <a href="javascript:ShowArticleGrant(14);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow15"> <td style="min-width: 40px; text-align: center;"> 15 </td> <td> <div id="citation15" class="article-citation"> <b>Day JH</b>, Della Santina CM, Maretich P, Auld AL, Schnieder KK, Shin T, Boyden ES, Boyer LA. High-throughput expansion microscopy enables scalable super-resolution imaging. <em class='incite-journal-name' onclick='ShowInCiteJournal(8168);'>eLife</em> 2024;<b>13</b>:RP96025. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39589396' target='_blank'>39589396</a> DOI: <a href='https://dx.doi.org/10.7554/elife.96025' target='_blank'>10.7554/elife.96025</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.7554/elife.96025','39589396', 'human')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(15);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(15);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(15);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(15);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.7554/elife.96025' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(8168);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/27/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv15" value="10.7554/elife.96025" /> <div style="display: none" id="articleAbstract15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Expansion microscopy (ExM) enables nanoscale imaging using a standard confocal microscope through the physical, isotropic expansion of fixed immunolabeled specimens. ExM is widely employed to image proteins, nucleic acids, and lipid membranes in single cells; however, current methods limit the number of samples that can be processed simultaneously. We developed High-throughput Expansion Microscopy (HiExM), a robust platform that enables expansion microscopy of cells cultured in a standard 96-well plate. Our method enables ~4.2 x expansion of cells within individual wells, across multiple wells, and between plates. We also demonstrate that HiExM can be combined with high-throughput confocal imaging platforms to greatly improve the ease and scalability of image acquisition. As an example, we analyzed the effects of doxorubicin, a known cardiotoxic agent, on human cardiomyocytes (CMs) as measured by the Hoechst signal across the nucleus. We show a dose-dependent effect on nuclear DNA that is not observed in unexpanded CMs, suggesting that HiExM improves the detection of cellular phenotypes in response to drug treatment. Our method broadens the application of ExM as a tool for scalable super-resolution imaging in biological research applications. </div> <a href="javascript:ShowArticleAbstract(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22A549+cells%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">A549 cells</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22cardiomyocytes%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">cardiomyocytes</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22cell+biology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">cell biology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22cell+culture%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">cell culture</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human</a></li></ul> <a href="javascript:ShowArticleKeywords(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Myocytes%2c+Cardiac%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Myocytes, Cardiac/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Doxorubicin%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Doxorubicin/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Microscopy%2c+Confocal%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Microscopy, Confocal/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22High-Throughput+Screening+Assays%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">High-Throughput Screening Assays/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cells%2c+Cultured%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cells, Cultured</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Microscopy%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Microscopy/methods</a></li></ul> <a href="javascript:ShowArticleMeSH(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIH+Office+of+the+Director%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">OD-026839-01 NIH Office of the Director</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22National+Science+Foundation+Graduate+Research+Fellowship+Program%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">2141064 National Science Foundation Graduate Research Fellowship Program</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22National+Science+Foundation+Graduate+Research+Fellowship+Program%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">1122374 National Science Foundation Graduate Research Fellowship Program</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIH+Office+of+the+Director%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">EB024261 NIH Office of the Director</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIH+Office+of+the+Director%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">1R01AG070831 NIH Office of the Director</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIH+Office+of+the+Director%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">1R01MH123403 NIH Office of the Director</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIH+Office+of+the+Director%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">R01MH124606 NIH Office of the Director</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIH+Office+of+the+Director%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">1R56AG069192 NIH Office of the Director</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIH+Office+of+the+Director%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">R01HL140471 NIH Office of the Director</a></li></ul> <a href="javascript:ShowArticleGrant(15);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow16"> <td style="min-width: 40px; text-align: center;"> 16 </td> <td> <div id="citation16" class="article-citation"> <b>Tilk S</b>, Frydman J, Curtis C, Petrov DA. Cancers adapt to their mutational load by buffering protein misfolding stress. <em class='incite-journal-name' onclick='ShowInCiteJournal(8168);'>eLife</em> 2024;<b>12</b>:RP87301. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39585785' target='_blank'>39585785</a> DOI: <a href='https://dx.doi.org/10.7554/elife.87301' target='_blank'>10.7554/elife.87301</a>]<span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.referencecitationanalysis.com/citearticles?term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22c%22%2c%22o%22%3anull%2c%22v%22%3a%2210.7554%2felife.87301%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d' target='_blank'>Citation(s) in <i>RCA</i>: 2</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInflu('10.7554%2felife.87301')">Impact Index Per Article: 2.0</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.7554/elife.87301','39585785', 'human')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(16);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(16);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(16);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(16);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.7554/elife.87301' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(8168);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/27/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv16" value="10.7554/elife.87301" /> <div style="display: none" id="articleAbstract16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">In asexual populations that don't undergo recombination, such as cancer, deleterious mutations are expected to accrue readily due to genome-wide linkage between mutations. Despite this mutational load of often thousands of deleterious mutations, many tumors thrive. How tumors survive the damaging consequences of this mutational load is not well understood. Here, we investigate the functional consequences of mutational load in 10,295 human tumors by quantifying their phenotypic response through changes in gene expression. Using a generalized linear mixed model (GLMM), we find that high mutational load tumors up-regulate proteostasis machinery related to the mitigation and prevention of protein misfolding. We replicate these expression responses in cancer cell lines and show that the viability in high mutational load cancer cells is strongly dependent on complexes that degrade and refold proteins. This indicates that the upregulation of proteostasis machinery is causally important for high mutational burden tumors and uncovers new therapeutic vulnerabilities. </div> <a href="javascript:ShowArticleAbstract(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22cancer%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">cancer</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22cancer+biology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">cancer biology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22evolutionary+biology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">evolutionary biology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22mutational+load%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">mutational load</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22proteostasis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">proteostasis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22somatic+evolution%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">somatic evolution</a></li></ul> <a href="javascript:ShowArticleKeywords(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neoplasms%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neoplasms/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neoplasms%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neoplasms/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mutation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mutation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Protein+Folding%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Protein Folding</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Proteostasis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Proteostasis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+Line%2c+Tumor%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell Line, Tumor</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Regulation%2c+Neoplastic%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Regulation, Neoplastic</a></li></ul> <a href="javascript:ShowArticleMeSH(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">GM74074 NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">R35GM118165 NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">DP1CA238296 NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NCI+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">U01CA217851 NCI NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">T32-HG000044-21 NIH HHS</a></li></ul> <a href="javascript:ShowArticleGrant(16);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow17"> <td style="min-width: 40px; text-align: center;"> 17 </td> <td> <div id="citation17" class="article-citation"> <b>Lee SS</b>, Civitelli L, Parkkinen L. Brain-derived and in vitro-seeded alpha-synuclein fibrils exhibit distinct biophysical profiles. <em class='incite-journal-name' onclick='ShowInCiteJournal(8168);'>eLife</em> 2024;<b>13</b>:RP92775. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39584804' target='_blank'>39584804</a> DOI: <a href='https://dx.doi.org/10.7554/elife.92775' target='_blank'>10.7554/elife.92775</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.7554/elife.92775','39584804', 'human')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(17);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(17);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(17);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.7554/elife.92775' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(8168);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/26/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv17" value="10.7554/elife.92775" /> <div style="display: none" id="articleAbstract17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">The alpha-synuclein (αSyn) seeding ampliﬁcation assay (SAA) that allows the generation of disease-speciﬁc in vitro seeded ﬁbrils (SAA ﬁbrils) is used as a research tool to study the connection between the structure of αSyn fibrils, cellular seeding/spreading, and the clinicopathological manifestations of different synucleinopathies. However, structural differences between human brain-derived and SAA αSyn ﬁbrils have been recently highlighted. Here, we characterize the biophysical properties of the human brain-derived αSyn ﬁbrils from the brains of patients with Parkinson's disease with and without dementia (PD, PDD), dementia with Lewy bodies (DLB), multiple system atrophy (MSA), and compare them to the 'model' SAA ﬁbrils. We report that the brain-derived αSyn ﬁbrils show distinct biochemical proﬁles, which were not replicated in the corresponding SAA ﬁbrils. Furthermore, the brain-derived αSyn ﬁbrils from all synucleinopathies displayed a mixture of 'straight' and 'twisted' microscopic structures. However, the PD, PDD, and DLB SAA ﬁbrils had a 'straight' structure, whereas MSA SAA ﬁbrils showed a 'twisted' structure. Finally, the brain-derived αSyn ﬁbrils from all four synucleinopathies were phosphorylated (S129). Interestingly, phosphorylated αSyn were carried over to the PDD and DLB SAA fibrils. Our ﬁndings demonstrate the limitation of the SAA ﬁbrils modeling the brain-derived αSyn ﬁbrils and pay attention to the necessity of deepening the understanding of the SAA fibrillation methodology. </div> <a href="javascript:ShowArticleAbstract(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Alpha-synuclein%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Alpha-synuclein</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Synucleinopathies%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Synucleinopathies</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22neuroscience%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">neuroscience</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22seeded+amplification+assay%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">seeded amplification assay</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22strains%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">strains</a></li></ul> <a href="javascript:ShowArticleKeywords(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22alpha-Synuclein%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">alpha-Synuclein/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22alpha-Synuclein%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">alpha-Synuclein/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Parkinson+Disease%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Parkinson Disease/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Parkinson+Disease%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Parkinson Disease/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Synucleinopathies%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Synucleinopathies/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Synucleinopathies%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Synucleinopathies/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Lewy+Body+Disease%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Lewy Body Disease/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Lewy+Body+Disease%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Lewy Body Disease/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Multiple+System+Atrophy%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Multiple System Atrophy/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Multiple+System+Atrophy%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Multiple System Atrophy/pathology</a></li></ul> <a href="javascript:ShowArticleMeSH(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(17);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow18"> <td style="min-width: 40px; text-align: center;"> 18 </td> <td> <div id="citation18" class="article-citation"> <b>Hayatigolkhatmi K</b>, Soriani C, Soda E, Ceccacci E, El Menna O, Peri S, Negrelli I, Bertolini G, Franchi GM, Carbone R, Minucci S, Rodighiero S. Automated workflow for the cell cycle analysis of (non-)adherent cells using a machine learning approach. <em class='incite-journal-name' onclick='ShowInCiteJournal(8168);'>eLife</em> 2024;<b>13</b>:RP94689. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39576677' target='_blank'>39576677</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11584176' target='_blank'>PMC11584176</a> DOI: <a href='https://dx.doi.org/10.7554/elife.94689' target='_blank'>10.7554/elife.94689</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.7554/elife.94689','39576677', 'human')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(18);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(18);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(18);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(18);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.7554/elife.94689' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(8168);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/24/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv18" value="10.7554/elife.94689" /> <div style="display: none" id="articleAbstract18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Understanding the cell cycle at the single-cell level is crucial for cellular biology and cancer research. While current methods using fluorescent markers have improved the study of adherent cells, non-adherent cells remain challenging. In this study, we addressed this gap by combining a specialized surface to enhance cell attachment, the FUCCI(CA)2 sensor, an automated image analysis pipeline, and a custom machine learning algorithm. This approach enabled precise measurement of cell cycle phase durations in non-adherent cells. This method was validated in acute myeloid leukemia cell lines NB4 and Kasumi-1, which have unique cell cycle characteristics, and we tested the impact of cell cycle-modulating drugs on NB4 cells. Our cell cycle analysis system, which is also compatible with adherent cells, is fully automated and freely available, providing detailed insights from hundreds of cells under various conditions. This report presents a valuable tool for advancing cancer research and drug development by enabling comprehensive, automated cell cycle analysis in both adherent and non-adherent cells. </div> <a href="javascript:ShowArticleAbstract(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22AML%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">AML</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22cancer+biology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">cancer biology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22cell+biology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">cell biology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22cell+cycle%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">cell cycle</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22cell+tracking%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">cell tracking</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22live-cell+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">live-cell imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22machine+learning%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">machine learning</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22non-adherent+cells%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">non-adherent cells</a></li></ul> <a href="javascript:ShowArticleKeywords(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Machine+Learning%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Machine Learning</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+Cycle%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell Cycle</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+Line%2c+Tumor%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell Line, Tumor</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+Adhesion%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell Adhesion</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Workflow%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Workflow</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Image+Processing%2c+Computer-Assisted%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Image Processing, Computer-Assisted/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Automation%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Automation/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Leukemia%2c+Myeloid%2c+Acute%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Leukemia, Myeloid, Acute/pathology</a></li></ul> <a href="javascript:ShowArticleMeSH(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Fondazione+AIRC+per+la+ricerca+sul+cancro+ETS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">28467 Fondazione AIRC per la ricerca sul cancro ETS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Marie+Sk%c5%82odowska-Curie+Innovative+Training+Network%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">10.3030/813327 Marie Skłodowska-Curie Innovative Training Network</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Fondazione+AIRC+per+la+ricerca+sul+cancro+ETS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">IG20 Fondazione AIRC per la ricerca sul cancro ETS</a></li></ul> <a href="javascript:ShowArticleGrant(18);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow19"> <td style="min-width: 40px; text-align: center;"> 19 </td> <td> <div id="citation19" class="article-citation"> <b>Das D</b>, Sharma M, Gahlot D, Nia SS, Gain C, Mecklenburg M, Zhou ZH, Bourdenx M, Thukral L, Martinez-Lopez N, Singh R. VPS4A is the selective receptor for lipophagy in mice and <span class="highlight-field">human</span>s. <em class='incite-journal-name' onclick='ShowInCiteJournal(17008);'>Mol Cell</em> 2024;<b>84</b>:4436-4453.e8. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39520981' target='_blank'>39520981</a> DOI: <a href='https://dx.doi.org/10.1016/j.molcel.2024.10.022' target='_blank'>10.1016/j.molcel.2024.10.022</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.molcel.2024.10.022','39520981', 'human')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(19);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(19);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(19);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.molcel.2024.10.022' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(17008);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/06/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/22/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/16/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/16/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv19" value="10.1016/j.molcel.2024.10.022" /> <div style="display: none" id="articleAbstract19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Lipophagy is a ubiquitous mechanism for degradation of lipid droplets (LDs) in lysosomes. Autophagy receptors selectively target organelles for lysosomal degradation. The selective receptor for lipophagy remains elusive. Using mouse liver phosphoproteomics and human liver transcriptomics, we identify vacuolar-protein-sorting-associated protein 4A (VPS4A), a member of a large family AAA+ ATPases, as a selective receptor for lipophagy. We show that phosphorylation of VPS4A on Ser95,97 and its localization to LDs in response to fasting drives lipophagy. Imaging/three-dimensional (3D) reconstruction and biochemical analyses reveal the concomitant degradation of VPS4A and LDs in lysosomes in an autophagy-gene-7-sensitive manner. Either silencing VPS4A or targeting VPS4AS95,S97 phosphorylation or VPS4A binding to LDs or LC3 blocks lipophagy without affecting other forms of selective autophagy. Finally, VPS4A levels and markers of lipophagy are markedly reduced in human steatotic livers-revealing a fundamental role of VPS4A as the lipophagy receptor in mice and humans. </div> <a href="javascript:ShowArticleAbstract(19);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22MASLD%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">MASLD</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22VPS4A%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">VPS4A</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22autophagy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">autophagy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22lipid+droplet%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">lipid droplet</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22lipophagy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">lipophagy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22liver%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">liver</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22lysosome%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">lysosome</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22phosphorylation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">phosphorylation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22receptor%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">receptor</a></li></ul> <a href="javascript:ShowArticleKeywords(19);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a 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ND, Abel L, Nagata S, Huse M, Miller WT, Casanova JL, Geissmann F. ACK1 and BRK non-receptor tyrosine kinase deficiencies are associated with familial systemic lupus and involved in efferocytosis. <em class='incite-journal-name' onclick='ShowInCiteJournal(8168);'>eLife</em> 2024;<b>13</b>:RP96085. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39570652' target='_blank'>39570652</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11581429' target='_blank'>PMC11581429</a> DOI: <a href='https://dx.doi.org/10.7554/elife.96085' target='_blank'>10.7554/elife.96085</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.7554/elife.96085','39570652', 'human')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(20);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(20);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(20);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(20);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.7554/elife.96085' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(8168);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/22/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv20" value="10.7554/elife.96085" /> <div style="display: none" id="articleAbstract20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Systemic lupus erythematosus (SLE) is an autoimmune disease, the pathophysiology and genetic basis of which are incompletely understood. Using a forward genetic screen in multiplex families with SLE, we identified an association between SLE and compound heterozygous deleterious variants in the non-receptor tyrosine kinases (NRTKs) ACK1 and BRK. Experimental blockade of ACK1 or BRK increased circulating autoantibodies in vivo in mice and exacerbated glomerular IgG deposits in an SLE mouse model. Mechanistically, NRTKs regulate activation, migration, and proliferation of immune cells. We found that the patients' ACK1 and BRK variants impair efferocytosis, the MERTK-mediated anti-inflammatory response to apoptotic cells, in human induced pluripotent stem cell (hiPSC)-derived macrophages, which may contribute to SLE pathogenesis. Overall, our data suggest that ACK1 and BRK deficiencies are associated with human SLE and impair efferocytosis in macrophages. </div> <a href="javascript:ShowArticleAbstract(20);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22ACK1%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">ACK1</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22BRK%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">BRK</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22genetic+diseases%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">genetic diseases</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22genetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22genomics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">genomics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22immunology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">immunology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22inflammation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">inflammation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22mouse%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">mouse</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22systemic+lupus%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">systemic lupus</a></li></ul> <a href="javascript:ShowArticleKeywords(20);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh20" class="article-abstract"> <b style="display: block; 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text-align: center;"> 21 </td> <td> <div id="citation21" class="article-citation"> <b>Haynesworth K</b>, Kemp TJ, Loftus SA, Metz J, Castro NC, Bullock J, Fetterer D, Pinto LA. Analytical measuring interval, linearity, and precision of serology assays for detection of SARS-CoV-2 antibodies according to CLSI guidelines. <em class='incite-journal-name' onclick='ShowInCiteJournal(17474);'>mSphere</em> 2024;<b>9</b>:e0039324. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39480103' target='_blank'>39480103</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11580426' target='_blank'>PMC11580426</a> DOI: <a href='https://dx.doi.org/10.1128/msphere.00393-24' target='_blank'>10.1128/msphere.00393-24</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1128/msphere.00393-24','39480103', 'human')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(21);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(21);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(21);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(21);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1128/msphere.00393-24' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(17474);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/09/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/02/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/02/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv21" value="10.1128/msphere.00393-24" /> <div style="display: none" id="articleAbstract21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Serology testing is commonly used to evaluate the immunogenicity of COVID-19 vaccines and measure antibodies as a marker of previous infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this study, four laboratory-developed serology enzyme-linked immunosorbent assays (SARS-CoV-2 anti-Spike and anti-Nucleocapsid immunoglobin G [IgG] and immunoglobin M [IgM]) calibrated to the WHO International Standard 20/136 were validated via analytical measuring interval (limit of blank [LOB], limit of detection [LOD], and limit of quantification [LOQ]), linearity, and precision according to the Clinical and Laboratory Standards Institute (CLSI) guidelines EP17-A2, EP06 2nd Edition, and EP05-A3. For Spike IgG, LOB was 3.0 binding antibody units per milliliter (BAU/mL), LOD was 4.1 BAU/mL, and LOQ was 27.1 BAU/mL. For Nucleocapsid IgG, LOB was 1.9 BAU/mL, LOD was 3.2 BAU/mL, and LOQ was 24.6 BAU/mL. For Spike IgM, LOB was 57.1 BAU/mL, LOD was 69.0 BAU/mL, and LOQ was 113.5 BAU/mL. For Nucleocapsid IgM, LOD was 242.2 BAU/mL, LOD was 289.9 BAU/mL, and LOQ was 572.4 BAU/mL. Each assay displayed good linearity (max % deviation from linearity (≥LOQ) = 10.7%). The result of within-run repeatability evaluation for medium positive samples was 7.7% for Spike IgG, 4.6% for Nucleocapsid IgG, 7.5% for Spike IgM, and 10.1% for Nucleocapsid IgM. The total precision, including medium positive sample variability across 20 days, three reagent kits, and two operators, was 13.5% for Spike IgG, 14.5% for Nucleocapsid IgG, 17.6% for Spike IgM, and 16.2% for Nucleocapsid IgM. The assays were successfully validated following the applicable CLSI guidelines. All assays met the ±20% deviation from linearity and the ±20% coefficient of variation specification for precision and repeatability. </div><div class="abstract-label">IMPORTANCE</div><div class="abstract-content">Reliable and validated serology assays are of increasing importance as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus continues to evolve and cause outbreaks. Validation of serology assays along with calibration to the International and National Standards (such as anti-SARS-CoV-2 Immunoglobulin WHO International Standard 20/136 or Frederick National Laboratory for Cancer Research's National Serology Standard COVID-NS01097) is critical to ensuring that results from clinical studies are reliable and comparable among various assays and laboratories. We describe the design and execution of a comprehensive study that established the analytical measuring intervals, linearity, precision, and repeatability of four in-house developed serology enzyme-linked immunosorbent assays (SARS-CoV-2 anti-Spike immunoglobin G [IgG] and immunoglobin M [IgM] and anti-Nucleocapsid IgG and IgM) following applicable Clinical and Laboratory Standards Institute (CLSI) guidelines. Overall, this study provides practical guidance on experimental design strategies and data analysis techniques, pertaining to the validation of COVID-19 serology assays according to CLSI guidelines, for use in clinical research studies. </div> <a href="javascript:ShowArticleAbstract(21);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22CLSI%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">CLSI</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22IgG%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">IgG</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22IgM%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">IgM</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nucleocapsid%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nucleocapsid</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22SARS-CoV-2%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">SARS-CoV-2</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Spike%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Spike</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22analytical+measuring+interval%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">analytical measuring interval</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22enzyme-linked+immunosorbent+assay+(ELISA)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">enzyme-linked immunosorbent assay (ELISA)</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22linearity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">linearity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22plasma%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">plasma</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22precision%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">precision</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22serology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">serology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22serum%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">serum</a></li></ul> <a href="javascript:ShowArticleKeywords(21);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh21" class="article-abstract"> <b style="display: block; 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padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NCI+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">75N91019D00024 NCI NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22HHS+%7c+NIH+%7c+National+Cancer+Institute+(NCI)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">HHS | NIH | National Cancer Institute (NCI)</a></li></ul> <a href="javascript:ShowArticleGrant(21);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow22"> <td style="min-width: 40px; text-align: center;"> 22 </td> <td> <div id="citation22" class="article-citation"> <b>Ennasr A</b>, Isaac G, Strohman A, Legon W. Examination of the interaction of parameters for low-intensity focused ultrasound of the <span class="highlight-field">human</span> motor cortex. <em class='incite-journal-name' onclick='ShowInCiteJournal(4017);'>Brain Stimul</em> 2024:S1935-861X(24)00189-X. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39577741' target='_blank'>39577741</a> DOI: <a href='https://dx.doi.org/10.1016/j.brs.2024.11.005' target='_blank'>10.1016/j.brs.2024.11.005</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.brs.2024.11.005','39577741', 'human')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(22);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(22);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.brs.2024.11.005' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(4017);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/27/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/28/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 11/07/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/24/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv22" value="10.1016/j.brs.2024.11.005" /> <div style="display: none" id="articleAbstract22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">Low-intensity focused ultrasound (LIFU) is a promising form of non-invasive neuromodulation characterized by a rich parameter space that includes intensity, duration, duty cycle and pulsing strategy. The effect and interaction of these parameters to affect human brain activity is poorly understood. A better understanding of how parameters interact is critical to advance LIFU as a potential therapeutic. </div><div class="abstract-label">OBJECTIVE/HYPOTHESIS</div><div class="abstract-content">To determine how intensity, duration, and duty cycle interact to produce neuromodulation effects in the human motor cortex. Further, this study assesses the effect of pulsing versus continuous ultrasound. We hypothesize that higher duty cycles will confer excitation. Increasing intensity or duration will increase the magnitude of effect. Pulsing LIFU will not be more effective than continuous wave ultrasound. </div><div class="abstract-label">METHODS</div><div class="abstract-content">N = 18 healthy human volunteers underwent 20 different parameter combinations that included a fully parametrized set of two intensities (ISPPA: 6 & 24 W/cm2), five duty cycles (1, 10, 30, 50, 70%) and two durations (100, 500 msec) with a constant pulse repetition frequency of 1 kHz delivered concurrently with transcranial magnetic stimulation (TMS) to the primary motor cortex (M1). Four of these parameter combinations were also delivered continuously, matched on the number of cycles. Motor-evoked potential (MEP) amplitude was the primary outcome measure. All parameter combinations were collected time-locked to MEP generation. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">There was no evidence of excitation from any parameter combination. 3 of the 24 parameter sets resulted in significant inhibition. The parameter set that resulted in the greatest inhibition (∼ 30%) was an intensity of 6W/cm2 with a duty cycle of 30% and a duration of 500 msec. A three-way ANOVA revealed an interaction of intensity and duty cycle. The analysis of continuous versus pulsed ultrasound revealed a 3-way interaction of intensity, pulsing, and the number of cycles such that under the 6W/cm2 condition higher cycles of pulsed ultrasound resulted in inhibition whereas lower number of cycles using continuous LIFU resulted in inhibition. </div><div class="abstract-label">CONCLUSIONS</div><div class="abstract-content">LIFU to M1 in humans, in the range employed, either conferred inhibition or had no effect. Significant excitation was not observed. In general, lower intensity looks to be more efficacious for inhibition that depends on duration. In addition, pulsed ultrasound looks to be more effective for inhibition as compared to continuous wave after controlling for total energy delivered. Non-specific auditory effects may contribute to these results. </div> <a href="javascript:ShowArticleAbstract(22);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Low-intensity+focused+ultrasound%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Low-intensity focused ultrasound</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22TMS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">TMS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22motor+evoked+potential%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">motor evoked potential</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22parameters%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">parameters</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22primary+motor+cortex%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">primary motor cortex</a></li></ul> <a href="javascript:ShowArticleKeywords(22);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(22);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(22);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow23"> <td style="min-width: 40px; text-align: center;"> 23 </td> <td> <div id="citation23" class="article-citation"> <b>Hardikar S</b>, Mckeown B, Schaare HL, Wallace RS, Xu T, Lauckener ME, Valk SL, Margulies DS, Turnbull A, Bernhardt BC, Vos de Wael R, Villringer A, Smallwood J. Macro-scale patterns in functional connectivity associated with ongoing thought patterns and dispositional traits. <em class='incite-journal-name' onclick='ShowInCiteJournal(8168);'>eLife</em> 2024;<b>13</b>:RP93689. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39565648' target='_blank'>39565648</a> DOI: <a href='https://dx.doi.org/10.7554/elife.93689' target='_blank'>10.7554/elife.93689</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.7554/elife.93689','39565648', 'human')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(23);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(23);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(23);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(23);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.7554/elife.93689' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(8168);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/21/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv23" value="10.7554/elife.93689" /> <div style="display: none" id="articleAbstract23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Complex macro-scale patterns of brain activity that emerge during periods of wakeful rest provide insight into the organisation of neural function, how these differentiate individuals based on their traits, and the neural basis of different types of self-generated thoughts. Although brain activity during wakeful rest is valuable for understanding important features of human cognition, its unconstrained nature makes it difficult to disentangle neural features related to personality traits from those related to the thoughts occurring at rest. Our study builds on recent perspectives from work on ongoing conscious thought that highlight the interactions between three brain networks - ventral and dorsal attention networks, as well as the default mode network. We combined measures of personality with state-of-the-art indices of ongoing thoughts at rest and brain imaging analysis and explored whether this 'tri-partite' view can provide a framework within which to understand the contribution of states and traits to observed patterns of neural activity at rest. To capture macro-scale relationships between different brain systems, we calculated cortical gradients to describe brain organisation in a low-dimensional space. Our analysis established that for more introverted individuals, regions of the ventral attention network were functionally more aligned to regions of the somatomotor system and the default mode network. At the same time, a pattern of detailed self-generated thought was associated with a decoupling of regions of dorsal attention from regions in the default mode network. Our study, therefore, establishes that interactions between attention systems and the default mode network are important influences on ongoing thought at rest and highlights the value of integrating contemporary perspectives on conscious experience when understanding patterns of brain activity at rest. </div> <a href="javascript:ShowArticleAbstract(23);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22macro-scale+connectivity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">macro-scale connectivity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22neuroscience%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">neuroscience</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22personality+traits%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">personality traits</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22spontaneous+thought%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">spontaneous thought</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22tri-partite+network%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">tri-partite network</a></li></ul> <a href="javascript:ShowArticleKeywords(23);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Personality%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Personality/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Magnetic+Resonance+Imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Magnetic Resonance Imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Young+Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Young Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Thinking%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Thinking/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nerve+Net%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nerve Net/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nerve+Net%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nerve Net/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Mapping%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Mapping</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rest%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rest/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Default+Mode+Network%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Default Mode Network/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Attention%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Attention/physiology</a></li></ul> <a href="javascript:ShowArticleMeSH(23);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Natural+Sciences+and+Engineering+Research+Council+of+Canada%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">#RGPIN 2023-03496 Natural Sciences and Engineering Research Council of Canada</a></li></ul> <a href="javascript:ShowArticleGrant(23);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow24"> <td style="min-width: 40px; text-align: center;"> 24 </td> <td> <div id="citation24" class="article-citation"> <b>Howard IS</b>, Franklin S, Franklin DW. Kernels of Motor Memory Formation: Temporal Generalization in Bimanual Adaptation. <em class='incite-journal-name' onclick='ShowInCiteJournal(169709);'>J Neurosci</em> 2024;<b>44</b>:e0359242024. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39358042' target='_blank'>39358042</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11580777' target='_blank'>PMC11580777</a> DOI: <a href='https://dx.doi.org/10.1523/jneurosci.0359-24.2024' target='_blank'>10.1523/jneurosci.0359-24.2024</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1523/jneurosci.0359-24.2024','39358042', 'human')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(24);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(24);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(24);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1523/jneurosci.0359-24.2024' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(169709);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 02/23/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/25/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/27/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/04/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv24" value="10.1523/jneurosci.0359-24.2024" /> <div style="display: none" id="articleAbstract24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">In daily life, we coordinate both simultaneous and sequential bimanual movements to manipulate objects. Our ability to rapidly account for different object dynamics suggests there are neural mechanisms to quickly deal with them. Here we investigate how actions of one arm can serve as a contextual cue for the other arm and facilitate adaptation. Specifically, we examine the temporal characteristics that underlie motor memory formation and recall, by testing the contextual effects of prior, simultaneous, and post contralateral arm movements in both male and female human participants. To do so, we measure their temporal generalization in three bimanual interference tasks. Importantly, the timing context of the learned action plays a pivotal role in the temporal generalization. While motor memories trained with post adaptation contextual movements generalize broadly, motor memories trained with prior contextual movements exhibit limited generalization, and motor memories trained with simultaneous contextual movements do not generalize to prior or post contextual timings. This highlights temporal tuning in sensorimotor plasticity: different training conditions yield substantially different temporal generalization characteristics. Since these generalizations extend far beyond any variability in training times, we suggest that the observed differences may stem from inherent differences in the use of prior, current, and post adaptation contextual information in the generation of natural behavior. This would imply differences in the underlying neural circuitry involved in learning and executing the corresponding coordinated bimanual movements. </div> <a href="javascript:ShowArticleAbstract(24);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22bimanual+context%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">bimanual context</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22dynamic+learning%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">dynamic learning</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22motor+learning%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">motor learning</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22temporal+generalization%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">temporal generalization</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22viscous+curl+field%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">viscous curl field</a></li></ul> <a href="javascript:ShowArticleKeywords(24);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Psychomotor+Performance%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Psychomotor Performance/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adaptation%2c+Physiological%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adaptation, Physiological/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Young+Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Young Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Generalization%2c+Psychological%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Generalization, Psychological/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Memory%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Memory/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Movement%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Movement/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Functional+Laterality%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Functional Laterality/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Time+Factors%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Time Factors</a></li></ul> <a href="javascript:ShowArticleMeSH(24);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(24);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow25"> <td style="min-width: 40px; text-align: center;"> 25 </td> <td> <div id="citation25" class="article-citation"> <b>Grogan JP</b>, Raemaekers M, van Swieten MMH, Green AL, Gillies MJ, Manohar SG. Muscarinic receptors mediate motivation via preparatory neural activity in <span class="highlight-field">human</span>s. <em class='incite-journal-name' onclick='ShowInCiteJournal(8168);'>eLife</em> 2024;<b>13</b>:RP98922. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39565722' target='_blank'>39565722</a> DOI: <a href='https://dx.doi.org/10.7554/elife.98922' target='_blank'>10.7554/elife.98922</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.7554/elife.98922','39565722', 'human')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(25);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(25);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(25);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(25);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.7554/elife.98922' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(8168);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/22/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv25" value="10.7554/elife.98922" /> <div style="display: none" id="articleAbstract25" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Motivation depends on dopamine, but might be modulated by acetylcholine which influences dopamine release in the striatum, and amplifies motivation in animal studies. A corresponding effect in humans would be important clinically, since anticholinergic drugs are frequently used in Parkinson's disease, a condition that can also disrupt motivation. Reward and dopamine make us more ready to respond, as indexed by reaction times (RT), and move faster, sometimes termed vigour. These effects may be controlled by preparatory processes that can be tracked using electroencephalography (EEG). We measured vigour in a placebo-controlled, double-blinded study of trihexyphenidyl (THP), a muscarinic antagonist, with an incentivised eye movement task and EEG. Participants responded faster and with greater vigour when incentives were high, but THP blunted these motivational effects, suggesting that muscarinic receptors facilitate invigoration by reward. Preparatory EEG build-up (contingent negative variation [CNV]) was strengthened by high incentives and by muscarinic blockade, although THP reduced the incentive effect. The amplitude of preparatory activity predicted both vigour and RT, although over distinct scalp regions; frontal activity predicted vigour, whereas a larger, earlier, central component predicted RT. The incentivisation of RT was partly mediated by the CNV, though vigour was not. Moreover, the CNV mediated the drug's effect on dampening incentives, suggesting that muscarinic receptors underlie the motivational influence on this preparatory activity. Taken together, these findings show that a muscarinic blocker impairs motivated action in healthy people, and that medial frontal preparatory neural activity mediates this for RT. </div> <a href="javascript:ShowArticleAbstract(25);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords25" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22EEG%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">EEG</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22acetylcholine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">acetylcholine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22human%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">human</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22motivation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">motivation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22neuroscience%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">neuroscience</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22reward%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">reward</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22saccade%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">saccade</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22vigour%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">vigour</a></li></ul> <a href="javascript:ShowArticleKeywords(25);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh25" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Motivation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Motivation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Electroencephalography%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Electroencephalography</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Receptors%2c+Muscarinic%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Receptors, Muscarinic/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Double-Blind+Method%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Double-Blind Method</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Young+Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Young Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reaction+Time%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reaction Time/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Muscarinic+Antagonists%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Muscarinic Antagonists/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reward%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reward</a></li></ul> <a href="javascript:ShowArticleMeSH(25);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant25" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Medical+Research+Council%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">MR/P00878X Medical Research Council</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Medical+Research+Council%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">MC_ST_U16042 Medical Research Council</a></li></ul> <a href="javascript:ShowArticleGrant(25);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> </tbody></table> <div class="search-pager-container"> <div class="dxpLite_MetropolisBlue" id="RootHolder_SearchResultPager" style="margin-top: 20px; margin-bottom: 20px;"> <b class="dxp-lead dxp-button dxp-bi dxp-disabledButton"><img class="dxWeb_pPrevDisabled_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Prev" /></b><b class="dxp-summary" style="margin-left:0px;">Page 1 of 425 </b><b class="dxp-num dxp-current page-number" style="margin-left:0px;">1</b><a class="dxp-num page-number" 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id="RootHolder_LeftLoadingPanel" style="position:absolute;left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="text-align:Center;vertical-align:Top;"><span id="RootHolder_LeftLoadingPanel_TL">Loading…</span></td> </tr> </table><div id="RootHolder_LeftLoadingPanel_LD" class="dxlpLoadingDiv_MetropolisBlue dxlpControl_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1950550554" type="text/javascript">  </script> <div id="RootHolder_articleCitationPopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:450px;width:600px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam"></span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content">    </div> </div> </div> </div><div id="RootHolder_articleCitationPopup_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_articleCitationPopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleCitationPopup_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleCitationPopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1115091042" type="text/javascript">  </script> <div id="RootHolder_chartPopupControl_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:1000px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_chartPopupControl_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam"></span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content" style="overflow-x:hidden;overflow-y:scroll;">    </div> </div> </div> </div><div id="RootHolder_chartPopupControl_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_chartPopupControl_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_chartPopupControl_TL">Loading…</span></td> </tr> </table><div id="RootHolder_chartPopupControl_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_420552910" type="text/javascript">  </script> <div id="RootHolder_pcImportArticlesControl_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:50px;width:50px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_pcImportArticlesControl_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Import Articles</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper" style="overflow:auto;"> <div class="dxpc-content"> </div> </div> </div> </div><div id="RootHolder_pcImportArticlesControl_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_pcImportArticlesControl_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_pcImportArticlesControl_TL">Loading…</span></td> </tr> </table><div id="RootHolder_pcImportArticlesControl_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_365297802" type="text/javascript">  </script> <div id="RootHolder_pcEditArticleControl_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:800px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_pcEditArticleControl_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Edit My Journal Article</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content" style="overflow-x:hidden;overflow-y:scroll;">    </div> </div> </div> </div><div id="RootHolder_pcEditArticleControl_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_pcEditArticleControl_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_pcEditArticleControl_TL">Loading…</span></td> </tr> </table><div id="RootHolder_pcEditArticleControl_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_298765222" type="text/javascript">  </script> <div id="RootHolder_userIndexComputePopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:200px;width:400px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header dxpc-withBtn" style="font-size:20px;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Article Influence Index</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="ai-content-container"> <p> <b>Calculation for <span id="RootHolder_userIndexComputePopup_InfluenceIndexTitle2">Article Influence Index</span></b> </p> <p> Total Citations in Crossref ÷ Total Articles = <span id="RootHolder_userIndexComputePopup_InfluenceIndexTitle3">Article Influence Index</span><sup class="standard-yellow">TM</sup> </p> </div> </div> </div> </div> </div><table id="RootHolder_userIndexComputePopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_userIndexComputePopup_TL">Loading…</span></td> </tr> </table><div id="RootHolder_userIndexComputePopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1286575841" type="text/javascript">  </script> <div id="RootHolder_articleExportPopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:280px;width:800px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow" style="font-size:11pt;"> <div class="dxpc-header drag dxpc-withBtn" style="font-size:20px;user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_articleExportPopup_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Export Articles to File</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="dxtcLite_MetropolisBlue dxtcSys dxtc-init dxtc-top dxtc-pc" id="RootHolder_articleExportPopup_ExportFilePageControl" style="width:100%;"> <ul class="dxtc-strip dxtc-row dxtc-stripContainer"> <li class="dxtc-leftIndent"> </li><li class="dxtc-tab dxtc-lead" style="display:none;"><a class="dxtc-link"><span class="dx-vam">Export Article Detail</span></a></li><li class="dxtc-activeTab dxtc-lead"><a class="dxtc-link"><span class="dx-vam">Export Article Detail</span></a></li><li class="dxtc-spacer"> </li><li class="dxtc-tab dxtc-last"><a class="dxtc-link"><span class="dx-vam">Export Citation Analysis</span></a></li><li class="dxtc-activeTab dxtc-last" style="display:none;"><a class="dxtc-link"><span class="dx-vam">Export Citation Analysis</span></a></li><li class="dxtc-rightIndent"> </li> </ul><div class="dxtc-content"> <div> <div> <div class="dxflFormLayout_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout" style="font-size:11pt;width:100%;"> <table class="dxflGroup_MetropolisBlue dxflGroupSys dxflAGSys" style="border-collapse:separate;"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_0" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_0_Cap" class="dxDefaultCursor dxflCaption_MetropolisBlue" style="font-weight:bold;">Searched Name:</span></td><td class="dxflNestedControlCell_MetropolisBlue"> <span class="dxeBase_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_SearchTermText1">human (10621 results from Reference Citation Analysis)</span> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_1" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="padding-bottom:5px;"> <table> <tr> <td> <span style="font-weight: bold">Article Number From</span> </td> <td>   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ExportDetailStartIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" value="1" type="text" /></td> </tr> </table><script id="dxss_1662381219" type="text/javascript">  </script> </td> <td>  to   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ExportDetailEndIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" value="600" type="text" /></td> </tr> </table><script id="dxss_616434442" type="text/javascript">  </script> </td> <td>  </td> <td>(No more than 600 records at a time.) </td> </tr> </table> </div></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_2" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_I" style="font-weight:bold;">Indexing:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$selectDetailSource" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-100" class="dxeButton dxeButtonEditButton_MetropolisBlue dxeButtonEditClearButton_MetropolisBlue" onmousedown="ASPx.BEClear('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="display:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-100Img" class="dxEditors_edtClear_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="x" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$selectDetailSource$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr> <td></td> </tr> </table> </div></td> </tr> </table><script id="dxss_1167331127" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_54524200" type="text/javascript">  </script><script id="dxss_1678130197" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_4" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_I" style="font-weight:bold;">JCR Year:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_VI" type="hidden" value="2023" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$JCRYear" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" value="2023" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$JCRYear$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2023</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2022</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2021</td> </tr> </table> </div></td> </tr> </table><script id="dxss_830317689" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_167955898" type="text/javascript">  </script><script id="dxss_2013408041" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_5" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_I" style="font-weight:bold;">Format:</label><em class="dxflRequired_MetropolisBlue">*</em></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_ET" class="dxeValidDynEditorTable dxeRoot_MetropolisBlue"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_CC"><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat" style="width:200px;border-collapse:separate;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$DetailFileFormat" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$DetailFileFormat$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Excel</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Plain Text</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">PDF</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">WORD</td> </tr> </table> </div></td> </tr> </table><script id="dxss_1062639383" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_104403608" type="text/javascript">  </script></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_EC" class="dxeErrorCell_MetropolisBlue dxeErrorFrame_MetropolisBlue dxeErrorFrameSys dxeErrorCellSys dxeNoBorderLeft" style="vertical-align:middle;display:none;white-space:nowrap;">Invalid value</td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1973673553" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_6" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLTSys dxflItemSys dxflCheckBoxWithTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields_S" style="font-weight:bold;">Record Content:</label></td> </tr><tr> <td class="dxflNestedControlCell_MetropolisBlue"> <table> <tr> <td style="vertical-align: middle; padding: 5px;"> <table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields" style="color:#BD4100;"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields_S" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$cbSelectAllFields" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label>Select All Fields</label></td> </tr> </table><script id="dxss_1176833720" type="text/javascript">  </script> </td> </tr> <tr> <td style="padding: 5px;"> <table class="dxeCheckBoxList_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields" style="width:100%;border-collapse:separate;"> <tr> <td class="dxe"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields" /><table style="width:100%;"> <tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB0"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB0_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB0" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Author(s)</label></td> </tr> </table><script id="dxss_771536870" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB1"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB1_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB1" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Article Title</label></td> </tr> </table><script id="dxss_1086331335" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB2"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB2_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB2" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Keywords</label></td> </tr> </table><script id="dxss_1308541020" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB3"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB3_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB3" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">MESH Headings</label></td> </tr> </table><script id="dxss_896786043" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB4"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB4_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB4" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Journal Title</label></td> </tr> </table><script id="dxss_450242410" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB5"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB5_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB5" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Year</label></td> </tr> </table><script id="dxss_765036875" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB6"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB6_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB6" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Article Type</label></td> </tr> </table><script id="dxss_1629835480" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB7"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB7_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB7" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Language</label></td> </tr> </table><script id="dxss_1218080503" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB8"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB8_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB8" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Published Date</label></td> </tr> </table><script id="dxss_1428514578" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB9"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB9_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB9" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">First Author</label></td> </tr> </table><script id="dxss_1113720113" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB10"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB10_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB10" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">First Author’s Affiliations</label></td> </tr> </table><script id="dxss_310841941" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB11"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB11_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB11" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Corresponding Author</label></td> </tr> </table><script id="dxss_1301541094" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB12"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB12_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB12" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Corresponding Author’s Affiliations</label></td> </tr> </table><script id="dxss_675718561" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB13"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB13_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB13" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Email</label></td> </tr> </table><script id="dxss_2006865700" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB14"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB14_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB14" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">All Authors's Affiliations</label></td> </tr> </table><script id="dxss_1204905793" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB15"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB15_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB15" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Grant</label></td> </tr> </table><script id="dxss_407477242" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB16"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB16_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB16" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">ISSN</label></td> </tr> </table><script id="dxss_218345291" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB17"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB17_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB17" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Publisher</label></td> </tr> </table><script id="dxss_1394037744" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB18"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB18_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB18" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Indexing / Abstracting</label></td> </tr> </table><script id="dxss_319681069" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB19"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB19_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB19" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">2023 Impact Factor</label></td> </tr> </table><script id="dxss_1292701966" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB20"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB20_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB20" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">2023 JCR Quartile</label></td> </tr> </table><script id="dxss_1844280938" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB21"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB21_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB21" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Impact Index Per Article</label></td> </tr> </table><script id="dxss_838303323" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB22"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB22_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB22" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Category</label></td> </tr> </table><script id="dxss_1464125856" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB23"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB23_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB23" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Times Cited in RCA</label></td> </tr> </table><script id="dxss_148257179" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB24"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB24_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB24" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Peer-Reviewed Journal</label></td> </tr> </table><script id="dxss_950217086" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB25"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB25_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB25" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Open Access</label></td> </tr> </table><script id="dxss_1732367175" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB26"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB26_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB26" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">DOI</label></td> </tr> </table><script id="dxss_1936777588" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB27"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB27_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB27" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">PMID</label></td> </tr> </table><script id="dxss_745806673" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB28"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB28_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB28" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Citation</label></td> </tr> </table><script id="dxss_1835441810" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB29"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB29_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB29" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Indexed in RCA</label></td> </tr> </table><script id="dxss_847142451" type="text/javascript">  </script></td><td></td><td></td> </tr> </table></td> </tr> </table><script id="dxss_427463133" type="text/javascript">  </script> </td> </tr> </table> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_7" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue"> <a class="dxeHyperlink_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportedDetailFileLink" target="_blank" rel="noopener noreferrer">Click to Download the Exported File</a><script id="dxss_1198171345" type="text/javascript">  </script> </div></td> </tr> </table> </div><script id="dxss_1960175520" type="text/javascript">  </script> </div> </div><div style="display:none;"> <div> <div class="dxflFormLayout_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout" style="font-size:11pt;width:100%;"> <table class="dxflGroup_MetropolisBlue dxflGroupSys dxflAGSys" style="border-collapse:separate;"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_0" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_0_Cap" class="dxDefaultCursor dxflCaption_MetropolisBlue" style="font-weight:bold;">Searched Name:</span></td><td class="dxflNestedControlCell_MetropolisBlue"> <span class="dxeBase_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_SearchTermText2">human (10621 results from Reference Citation Analysis)</span> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_1" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="padding-bottom:10px;"> <table> <tr> <td> <span style="font-weight: bold">Article Number From</span> </td> <td>   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$ExportStartIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" value="1" type="text" /></td> </tr> </table><script id="dxss_814491935" type="text/javascript">  </script> </td> <td>  to   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$ExportEndSIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" value="600" type="text" /></td> </tr> </table><script id="dxss_1331245653" type="text/javascript">  </script> </td> <td>  </td> <td>(No more than 600 records at a time.) </td> </tr> </table> </div></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_2" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:10px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_I" style="font-weight:bold;">Indexing:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$selectSource" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-100" class="dxeButton dxeButtonEditButton_MetropolisBlue dxeButtonEditClearButton_MetropolisBlue" onmousedown="ASPx.BEClear('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="display:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-100Img" class="dxEditors_edtClear_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="x" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$selectSource$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr> <td></td> </tr> </table> </div></td> </tr> </table><script id="dxss_2046065225" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_1926633208" type="text/javascript">  </script><script id="dxss_228619664" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_4" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:20px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_I" style="font-weight:bold;">Format:</label><em class="dxflRequired_MetropolisBlue">*</em></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_ET" class="dxeValidDynEditorTable dxeRoot_MetropolisBlue"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_CC"><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat" style="width:200px;border-collapse:separate;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_VI" type="hidden" value="1" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$FileFormat" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" value="Excel" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$FileFormat$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Excel</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Plain Text</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">PDF</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">WORD</td> </tr> </table> </div></td> </tr> </table><script id="dxss_1509722775" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_960798088" type="text/javascript">  </script></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_EC" class="dxeErrorCell_MetropolisBlue dxeErrorFrame_MetropolisBlue dxeErrorFrameSys dxeErrorCellSys dxeNoBorderLeft" style="vertical-align:middle;display:none;white-space:nowrap;">Invalid value</td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_835950349" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_5" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue"> <a class="dxeHyperlink_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportedFileLink" target="_blank" rel="noopener noreferrer">Click to Download the Exported File</a><script id="dxss_308093146" type="text/javascript">  </script> </div></td> </tr> </table> </div><script id="dxss_424125632" type="text/javascript">  </script> </div> </div> </div> </div><b class="dx-clear"></b><table id="RootHolder_articleExportPopup_ExportFilePageControl_LP" class="dxtcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_TL">Loading…</span></td> </tr> </table><script id="dxss_2124675053" type="text/javascript">  </script> </div> </div><div class="dxpc-footer"> <div class="popup-footer-button-container"> <div class="dxbButton_MetropolisBlue DefaultButton dxbButtonSys dxbTSys" id="RootHolder_articleExportPopup_TPCFm1_btnExportArticles" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxb"> <input id="RootHolder_articleExportPopup_TPCFm1_btnExportArticles_I" class="dxb-hb" value="Export" type="submit" name="ctl00$RootHolder$articleExportPopup$TPCFm1$TC$btnExportArticles" /><span class="dx-vam">Export</span> </div> </div><script id="dxss_77486387" type="text/javascript">  </script>    <div class="dxbButton_MetropolisBlue DefaultButton dxbButtonSys dxbTSys" id="RootHolder_articleExportPopup_TPCFm1_btnCancel" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxb"> <input id="RootHolder_articleExportPopup_TPCFm1_btnCancel_I" class="dxb-hb" value="Cancel" type="submit" name="ctl00$RootHolder$articleExportPopup$TPCFm1$TC$btnCancel" /><span class="dx-vam">Cancel</span> </div> </div><script id="dxss_2118985763" type="text/javascript">  </script> </div> </div> </div> </div><div id="RootHolder_articleExportPopup_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_articleExportPopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="font-size:11pt;left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="font-size:11pt;padding-left:0px;"><span id="RootHolder_articleExportPopup_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_578446409" type="text/javascript">  </script> </div> <div class="bottom-part cl"> © 2004-2024 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA </div> <div class="scroll"> <a href="#top" target="_self"> <img src="/Contents/Images/backtop3.png" /> </a> </div> <div id="categorySelectorPopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:800px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="font-size:20px;user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Select the Category</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper" style="overflow:auto;"> <div class="dxpc-content"> </div> </div> </div> </div><div id="categorySelectorPopup_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="categorySelectorPopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="categorySelectorPopup_TL">Loading…</span></td> </tr> </table><div id="categorySelectorPopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_166253781" type="text/javascript">  </script> <div id="pcLoginPopUp_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:700px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper" style="overflow:auto;"> <div class="dxpc-content"> </div> </div> </div> </div><div id="pcLoginPopUp_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="pcLoginPopUp_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="pcLoginPopUp_TL">Loading…</span></td> </tr> </table><div id="pcLoginPopUp_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_430910140" type="text/javascript">  </script> <div id="aiComputePopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:200px;width:300px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header dxpc-withBtn" style="font-size:20px;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Impact Index Per Article</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="ai-content-container"> <p> <b>Calculation for Impact Index Per Article</b> </p> <p> Times Cited ÷ Number of Years = Impact Index Per Article<sup class="standard-yellow">TM</sup> </p> </div> </div> </div> </div> </div><table id="aiComputePopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="aiComputePopup_TL">Loading…</span></td> </tr> </table><div id="aiComputePopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_698179129" type="text/javascript">  </script> <script type="text/javascript"> //<![CDATA[ var callBackFrameUrl='/WebResource.axd?d=beToSAE3vdsL1QUQUxjWdX-3aFLejnBliGvqSCZYULGFdxZmRlcJcqs71AKVNTQEXljNmd0slFkUZ_AFaCke4Q2&t=638628207619783110'; WebForm_InitCallback();//]]> </script> </form> </body> </html>