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style="--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:3%;--awb-padding-bottom:3%;--awb-padding-top-small:12%;--awb-padding-bottom-small:12%;--awb-background-image:linear-gradient(180deg, rgba(0,0,0,0.65) 0%,rgba(0,0,0,0.4) 100%);;--awb-background-size:cover;--awb-flex-wrap:wrap;background-attachment:fixed;" data-bg="https://biocomputationlab.com/wp-content/uploads/2022/05/bg_Research_v3.png" data-bg-gradient="linear-gradient(180deg, rgba(0,0,0,0.65) 0%,rgba(0,0,0,0.4) 100%)" ><div class="fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap" style="max-width:1216.8px;margin-left: calc(-4% / 2 );margin-right: calc(-4% / 2 );"><div class="fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_2_3 2_3 fusion-flex-column fusion-flex-align-self-center fusion-animated" style="--awb-bg-size:cover;--awb-width-large:66.666666666667%;--awb-margin-top-large:0px;--awb-spacing-right-large:2.88%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:2.88%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;" data-animationType="fadeIn" data-animationDuration="1.6" data-animationOffset="top-into-view"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"><div class="fusion-text fusion-text-1"><h1>Engineering microbes with new functionalities</h1> </div><div class="fusion-text fusion-text-2"><h2>We use living cells as substrate for computing </h2> </div><div class="fusion-separator" style="align-self: flex-start;margin-right:auto;margin-top:1%;margin-bottom:4%;width:100%;max-width:15%;"><div class="fusion-separator-border sep-single sep-solid" style="--awb-height:20px;--awb-amount:20px;border-color:var(--awb-color2);border-top-width:3px;"></div></div></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-1 fusion_builder_column_1_3 1_3 fusion-flex-column fusion-no-small-visibility" style="--awb-bg-size:cover;--awb-width-large:33.333333333333%;--awb-margin-top-large:0px;--awb-spacing-right-large:5.76%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:5.76%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"></div></div></div></div> </section> <main id="main" class="clearfix width-100"> <div class="fusion-row" style="max-width:100%;"> <section id="content" class="full-width"> <div id="post-5179" class="post-5179 page type-page status-publish has-post-thumbnail hentry"> <span class="entry-title rich-snippet-hidden">Research</span><span class="vcard rich-snippet-hidden"><span class="fn"><a href="https://biocomputationlab.com/author/d3veloperscs_biocomplab/" title="Posts by D3veloperSCS_biocomplab" rel="author">D3veloperSCS_biocomplab</a></span></span><span class="updated rich-snippet-hidden">2024-11-11T14:06:58+00:00</span> <div class="post-content"> <div id="research-lines" class="fusion-container-anchor"><div class="fusion-fullwidth fullwidth-box fusion-builder-row-2 fusion-flex-container fusion-parallax-fixed nonhundred-percent-fullwidth non-hundred-percent-height-scrolling lazyload" style="--awb-background-position:left bottom;--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:4%;--awb-padding-bottom:8%;--awb-padding-bottom-small:10%;--awb-background-color:var(--awb-color2);--awb-background-size:cover;--awb-flex-wrap:wrap;background-attachment:fixed;" data-bg="https://biocomputationlab.com/wp-content/uploads/2022/05/fondo_logo_v8.png" ><div class="fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap" style="max-width:1216.8px;margin-left: calc(-4% / 2 );margin-right: calc(-4% / 2 );"><div class="fusion-layout-column fusion_builder_column fusion-builder-column-2 fusion-flex-column" style="--awb-bg-size:cover;--awb-width-large:10%;--awb-margin-top-large:0px;--awb-spacing-right-large:19.2%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:19.2%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-3 fusion_builder_column_4_5 4_5 fusion-flex-column fusion-animated" style="--awb-bg-size:cover;--awb-width-large:80%;--awb-margin-top-large:0px;--awb-spacing-right-large:2.4%;--awb-margin-bottom-large:4%;--awb-spacing-left-large:2.4%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:1;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;" data-animationType="fadeInUp" data-animationDuration="1.3" data-animationOffset="top-into-view"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"><div class="fusion-text fusion-text-3"><h3 style="text-align: center;">Our research lines</h3> </div><div class="fusion-text fusion-text-4"><h4 style="text-align: center;">Harnessing the information-processing capacity of bacteria for new biological devices</h4> </div></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-4 fusion-flex-column" style="--awb-bg-size:cover;--awb-width-large:10%;--awb-margin-top-large:0px;--awb-spacing-right-large:19.2%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:19.2%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:2;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-5 fusion_builder_column_1_3 1_3 fusion-flex-column fusion-flex-align-self-center fusion-animated" style="--awb-bg-size:cover;--awb-width-large:33.333333333333%;--awb-margin-top-large:0px;--awb-spacing-right-large:5.76%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:5.76%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:83.333333333333%;--awb-order-small:4;--awb-spacing-right-small:2.304%;--awb-margin-bottom-small:6%;--awb-spacing-left-small:2.304%;" data-animationType="fadeInLeft" data-animationDuration="1.3" data-animationOffset="top-into-view"><div class="fusion-column-wrapper lazyload fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column fusion-column-has-bg-image" data-bg-url="https://biocomputationlab.com/wp-content/uploads/2022/05/engineered.png" data-bg="https://biocomputationlab.com/wp-content/uploads/2022/05/engineered.png"><div class="fusion-menu-anchor" id="engineered-biological-circuits"></div><div class="fusion-image-element " style="text-align:center;--awb-margin-top:5%;--awb-margin-right:5%;--awb-margin-bottom:5%;--awb-margin-left:5%;--awb-max-width:90%;--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);"><span class=" fusion-imageframe imageframe-none imageframe-1 hover-type-none fusion-animated" data-animationType="fadeIn" data-animationDuration="2.0" data-animationOffset="top-mid-of-view"><img fetchpriority="high" decoding="async" width="380" height="379" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27380%27%20height%3D%27379%27%20viewBox%3D%270%200%20380%20379%27%3E%3Crect%20width%3D%27380%27%20height%3D%27379%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E" data-orig-src="https://biocomputationlab.com/wp-content/uploads/2022/05/engineered_icon.svg" alt class="lazyload img-responsive wp-image-5261"/></span></div></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-6 fusion_builder_column_1_6 1_6 fusion-flex-column fusion-no-medium-visibility fusion-no-large-visibility" style="--awb-bg-size:cover;--awb-width-large:16.666666666667%;--awb-margin-top-large:0px;--awb-spacing-right-large:11.52%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:11.52%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:8.3%;--awb-order-small:5;--awb-spacing-right-small:23.132530120482%;--awb-spacing-left-small:23.132530120482%;"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-7 fusion_builder_column_1_6 1_6 fusion-flex-column fusion-no-medium-visibility fusion-no-large-visibility" style="--awb-bg-size:cover;--awb-width-large:16.666666666667%;--awb-margin-top-large:0px;--awb-spacing-right-large:11.52%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:11.52%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:8.3%;--awb-order-small:16;--awb-spacing-right-small:23.132530120482%;--awb-spacing-left-small:23.132530120482%;"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-8 fusion_builder_column_1_6 1_6 fusion-flex-column fusion-no-medium-visibility fusion-no-large-visibility" style="--awb-bg-size:cover;--awb-width-large:16.666666666667%;--awb-margin-top-large:0px;--awb-spacing-right-large:11.52%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:11.52%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:8.3%;--awb-order-small:14;--awb-spacing-right-small:23.132530120482%;--awb-spacing-left-small:23.132530120482%;"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-9 fusion_builder_column_1_6 1_6 fusion-flex-column fusion-no-medium-visibility fusion-no-large-visibility" style="--awb-bg-size:cover;--awb-width-large:16.666666666667%;--awb-margin-top-large:0px;--awb-spacing-right-large:11.52%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:11.52%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:8.3%;--awb-order-small:20;--awb-spacing-right-small:23.132530120482%;--awb-spacing-left-small:23.132530120482%;"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-10 fusion_builder_column_1_6 1_6 fusion-flex-column fusion-no-medium-visibility fusion-no-large-visibility" style="--awb-bg-size:cover;--awb-width-large:16.666666666667%;--awb-margin-top-large:0px;--awb-spacing-right-large:11.52%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:11.52%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:8.3%;--awb-order-small:18;--awb-spacing-right-small:23.132530120482%;--awb-spacing-left-small:23.132530120482%;"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-11 fusion_builder_column_1_6 1_6 fusion-flex-column fusion-no-medium-visibility fusion-no-large-visibility" style="--awb-bg-size:cover;--awb-width-large:16.666666666667%;--awb-margin-top-large:0px;--awb-spacing-right-large:11.52%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:11.52%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:8.3%;--awb-order-small:10;--awb-spacing-right-small:23.132530120482%;--awb-spacing-left-small:23.132530120482%;"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-12 fusion_builder_column_1_6 1_6 fusion-flex-column fusion-no-medium-visibility fusion-no-large-visibility" style="--awb-bg-size:cover;--awb-width-large:16.666666666667%;--awb-margin-top-large:0px;--awb-spacing-right-large:11.52%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:11.52%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:8.3%;--awb-order-small:12;--awb-spacing-right-small:23.132530120482%;--awb-spacing-left-small:23.132530120482%;"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-13 fusion_builder_column_1_6 1_6 fusion-flex-column fusion-no-medium-visibility fusion-no-large-visibility" style="--awb-bg-size:cover;--awb-width-large:16.666666666667%;--awb-margin-top-large:0px;--awb-spacing-right-large:11.52%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:11.52%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:8.3%;--awb-order-small:3;--awb-spacing-right-small:23.132530120482%;--awb-spacing-left-small:23.132530120482%;"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-14 fusion_builder_column_2_3 2_3 fusion-flex-column fusion-flex-align-self-center fusion-animated" style="--awb-bg-size:cover;--awb-width-large:66.666666666667%;--awb-margin-top-large:0px;--awb-spacing-right-large:2.88%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:2.88%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:9;--awb-spacing-right-small:1.92%;--awb-margin-bottom-small:12%;--awb-spacing-left-small:1.92%;" data-animationType="fadeInLeft" data-animationDuration="1.3" data-animationOffset="top-into-view"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"><div class="fusion-text fusion-text-5"><h4 style="font-size: 23px; color: #37493e;">Engineered biological circuits</h4> </div><div class="fusion-text fusion-text-6"><h5>Designing biocircuits to perform predefined functions</h5> </div><div class="fusion-text fusion-text-7"><p>Genetic and metabolic networks are like cascades of events triggered by certain inputs, such as environmental signals, to deliver outputs. We design and implement synthetic networks that <strong>process inputs into outputs </strong>according to predefined rules encoded in the genetics of microbes. This set of rules is equivalent to an algorithm. In other words, we <strong>program biocomputations</strong> that are <strong>tailored to</strong> an application or case study in the <strong>environmental field</strong>. We are currently working with the bacteria <em>E. coli</em>, <em>P. putida</em>, <em>G. sulfurreducens</em> and <em>P. protegens</em>.</p> </div></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-15 fusion_builder_column_1_1 1_1 fusion-flex-column" style="--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:1.92%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:6;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"><div class="fusion-separator fusion-no-small-visibility fusion-full-width-sep" style="align-self: center;margin-left: auto;margin-right: auto;margin-top:3%;margin-bottom:3%;width:100%;"></div></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-16 fusion_builder_column_2_3 2_3 fusion-flex-column fusion-flex-align-self-center fusion-animated" style="--awb-bg-size:cover;--awb-width-large:66.666666666667%;--awb-margin-top-large:0px;--awb-spacing-right-large:2.88%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:2.88%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:13;--awb-spacing-right-small:1.92%;--awb-margin-bottom-small:12%;--awb-spacing-left-small:1.92%;" data-animationType="fadeInRight" data-animationDuration="1.3" data-animationOffset="top-into-view"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"><div class="fusion-text fusion-text-8"><h4 style="font-size: 23px; color: #37493e;">Biological complexity: from context to evolution</h4> </div><div class="fusion-text fusion-text-9"><h5>Understanding how context affect performance</h5> </div><div class="fusion-text fusion-text-10"><p>Genetic circuits are much more than DNA sequences and they <strong>do not guarantee the same behaviour </strong>in different organisms. Their performance is influenced by how the host context interacts with the circuits, something we call <strong>contextual dependencies</strong>. Our aim is to characterise these interactions and modify the spatial structure of circuits and the extracellular environment to <strong>affect their</strong> <strong>performance</strong> without modifying the DNA. Ultimately, we aim to achieve the challenging goal of programming <strong>evolutionary dynamics</strong>.</p> </div></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-17 fusion_builder_column_1_3 1_3 fusion-flex-column fusion-flex-align-self-center fusion-animated" style="--awb-bg-size:cover;--awb-width-large:33.333333333333%;--awb-margin-top-large:0px;--awb-spacing-right-large:5.76%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:5.76%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:83.333333333333%;--awb-order-small:11;--awb-spacing-right-small:2.304%;--awb-margin-bottom-small:6%;--awb-spacing-left-small:2.304%;" data-animationType="fadeInRight" data-animationDuration="1.3" data-animationOffset="top-into-view"><div class="fusion-column-wrapper lazyload fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column fusion-column-has-bg-image" data-bg-url="https://biocomputationlab.com/wp-content/uploads/2022/05/biological-complexity_image.png" data-bg="https://biocomputationlab.com/wp-content/uploads/2022/05/biological-complexity_image.png"><div class="fusion-menu-anchor" id="biological-complexity"></div><div class="fusion-image-element " style="text-align:center;--awb-margin-top:5%;--awb-margin-right:5%;--awb-margin-bottom:5%;--awb-margin-left:5%;--awb-max-width:90%;--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);"><span class=" fusion-imageframe imageframe-none imageframe-2 hover-type-none fusion-animated" data-animationType="fadeIn" data-animationDuration="2.0" data-animationOffset="top-mid-of-view"><img decoding="async" width="380" height="380" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27380%27%20height%3D%27380%27%20viewBox%3D%270%200%20380%20380%27%3E%3Crect%20width%3D%27380%27%20height%3D%27380%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E" data-orig-src="https://biocomputationlab.com/wp-content/uploads/2022/05/biological-complex.svg" alt class="lazyload img-responsive wp-image-5268"/></span></div></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-18 fusion_builder_column_1_1 1_1 fusion-flex-column" style="--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:1.92%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:7;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"><div class="fusion-separator fusion-no-small-visibility fusion-full-width-sep" style="align-self: center;margin-left: auto;margin-right: auto;margin-top:3%;margin-bottom:3%;width:100%;"></div></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-19 fusion_builder_column_1_3 1_3 fusion-flex-column fusion-flex-align-self-center fusion-animated" style="--awb-bg-size:cover;--awb-width-large:33.333333333333%;--awb-margin-top-large:0px;--awb-spacing-right-large:5.76%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:5.76%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:83.333333333333%;--awb-order-small:15;--awb-spacing-right-small:2.304%;--awb-margin-bottom-small:6%;--awb-spacing-left-small:2.304%;" data-animationType="fadeInLeft" data-animationDuration="1.3" data-animationOffset="top-into-view"><div class="fusion-column-wrapper lazyload fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column fusion-column-has-bg-image" data-bg-url="https://biocomputationlab.com/wp-content/uploads/2022/06/mathematical_image_v3_research.png" data-bg="https://biocomputationlab.com/wp-content/uploads/2022/06/mathematical_image_v3_research.png"><div class="fusion-menu-anchor" id="mathematical-modelling"></div><div class="fusion-image-element " style="text-align:center;--awb-margin-top:5%;--awb-margin-right:5%;--awb-margin-bottom:5%;--awb-margin-left:5%;--awb-max-width:90%;--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);"><span class=" fusion-imageframe imageframe-none imageframe-3 hover-type-none fusion-animated" data-animationType="fadeIn" data-animationDuration="2.0" data-animationOffset="top-mid-of-view"><img decoding="async" width="380" height="379" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27380%27%20height%3D%27379%27%20viewBox%3D%270%200%20380%20379%27%3E%3Crect%20width%3D%27380%27%20height%3D%27379%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E" data-orig-src="https://biocomputationlab.com/wp-content/uploads/2022/05/mathematical.svg" alt class="lazyload img-responsive wp-image-5271"/></span></div></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-20 fusion_builder_column_2_3 2_3 fusion-flex-column fusion-flex-align-self-center fusion-animated" style="--awb-bg-size:cover;--awb-width-large:66.666666666667%;--awb-margin-top-large:0px;--awb-spacing-right-large:2.88%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:2.88%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:17;--awb-spacing-right-small:1.92%;--awb-margin-bottom-small:12%;--awb-spacing-left-small:1.92%;" data-animationType="fadeInLeft" data-animationDuration="1.3" data-animationOffset="top-into-view"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"><div class="fusion-text fusion-text-11"><h4 style="font-size: 23px; color: #37493e;">Mathematical modelling beyond experiments</h4> </div><div class="fusion-text fusion-text-12"><h5>Towards a comprehensive understanding of biological systems</h5> </div><div class="fusion-text fusion-text-13"><p>How does ribosome jamming alter translation? What are the effects of transcription-translation coupling of circuits? Can multicellular systems be effectively modulated? We use <strong>mathematical modelling</strong> and <strong>computational simulations</strong> to better understand <strong>how biological systems work</strong>. In addition, these tools allow us to <strong>design and predict</strong> the performance of new biological circuits, as well as to interpret experimental results to refine initial designs.</p> </div></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-21 fusion_builder_column_1_1 1_1 fusion-flex-column" style="--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:1.92%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:8;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"><div class="fusion-separator fusion-no-small-visibility fusion-full-width-sep" style="align-self: center;margin-left: auto;margin-right: auto;margin-top:3%;margin-bottom:3%;width:100%;"></div></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-22 fusion_builder_column_2_3 2_3 fusion-flex-column fusion-flex-align-self-center fusion-animated" style="--awb-bg-size:cover;--awb-width-large:66.666666666667%;--awb-margin-top-large:0px;--awb-spacing-right-large:2.88%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:2.88%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:21;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;" data-animationType="fadeInRight" data-animationDuration="1.3" data-animationOffset="top-into-view"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"><div class="fusion-text fusion-text-14"><h4 style="font-size: 23px; color: #37493e;">Standards, automation, and data handling</h4> </div><div class="fusion-text fusion-text-15"><h5>Committed to synthetic biology standardisation</h5> </div><div class="fusion-text fusion-text-16"><p>Our laboratory uses and has contributed to the <strong>Standard European Vector Architecture</strong> (SEVA) and the <strong>Synthetic Biology Open Language</strong> (SBOL). We are developing methods to visualise and edit design information in a user-friendly manner, and we use <strong>automation machinery</strong>. Ensuring that these and other automation facilities fit our laboratory’s requirements is a task in its own: we write protocols, methods, and calibration scripts, centralise information and engineer our own ad hoc solutions.</p> </div></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-23 fusion_builder_column_1_3 1_3 fusion-flex-column fusion-flex-align-self-center fusion-animated" style="--awb-bg-size:cover;--awb-width-large:33.333333333333%;--awb-margin-top-large:0px;--awb-spacing-right-large:5.76%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:5.76%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:83.333333333333%;--awb-order-small:19;--awb-spacing-right-small:2.304%;--awb-margin-bottom-small:6%;--awb-spacing-left-small:2.304%;" data-animationType="fadeInRight" data-animationDuration="1.3" data-animationOffset="top-into-view"><div class="fusion-column-wrapper lazyload fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column fusion-column-has-bg-image" data-bg-url="https://biocomputationlab.com/wp-content/uploads/2022/06/standards_image_v3_research.png" data-bg="https://biocomputationlab.com/wp-content/uploads/2022/06/standards_image_v3_research.png"><div class="fusion-menu-anchor" id="standards-automotion-data-handling"></div><div class="fusion-image-element " style="text-align:center;--awb-margin-top:5%;--awb-margin-right:5%;--awb-margin-bottom:5%;--awb-margin-left:5%;--awb-max-width:90%;--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);"><span class=" fusion-imageframe imageframe-none imageframe-4 hover-type-none fusion-animated" data-animationType="fadeIn" data-animationDuration="2.0" data-animationOffset="top-mid-of-view"><img decoding="async" width="380" height="380" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27380%27%20height%3D%27380%27%20viewBox%3D%270%200%20380%20380%27%3E%3Crect%20width%3D%27380%27%20height%3D%27380%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E" data-orig-src="https://biocomputationlab.com/wp-content/uploads/2022/05/standards.svg" alt class="lazyload img-responsive wp-image-5273"/></span></div></div></div></div></div></div><div id="ongoing-projects" class="fusion-container-anchor"><div class="fusion-fullwidth fullwidth-box fusion-builder-row-3 fusion-flex-container fusion-parallax-fixed nonhundred-percent-fullwidth non-hundred-percent-height-scrolling lazyload" style="--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:4%;--awb-padding-bottom:5%;--awb-background-color:#fafafc;--awb-background-image:linear-gradient(180deg, rgba(33,43,36,0.88) 0%,rgba(33,43,36,0.58) 100%);;--awb-background-size:cover;--awb-flex-wrap:wrap;background-attachment:fixed;" data-bg="https://biocomputationlab.com/wp-content/uploads/2022/05/bg_ongoing-projects.png" data-bg-gradient="linear-gradient(180deg, rgba(33,43,36,0.88) 0%,rgba(33,43,36,0.58) 100%)" ><div class="fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap" style="max-width:1216.8px;margin-left: calc(-4% / 2 );margin-right: calc(-4% / 2 );"><div class="fusion-layout-column fusion_builder_column fusion-builder-column-24 fusion-flex-column" style="--awb-bg-size:cover;--awb-width-large:10%;--awb-margin-top-large:0px;--awb-spacing-right-large:19.2%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:19.2%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-25 fusion_builder_column_4_5 4_5 fusion-flex-column fusion-animated" style="--awb-bg-size:cover;--awb-width-large:80%;--awb-margin-top-large:0px;--awb-spacing-right-large:2.4%;--awb-margin-bottom-large:4%;--awb-spacing-left-large:2.4%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;" data-animationType="fadeInUp" data-animationDuration="1.3" data-animationOffset="top-into-view"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"><div class="fusion-menu-anchor" id="ongoing-projects"></div><div class="fusion-text fusion-text-17"><h3 style="text-align: center; color: #ffffff;">Ongoing projects</h3> </div><div class="fusion-text fusion-text-18"><h4 style="text-align: center; color: rgba(255,255,255,0.87);">From evolution to standardisation, we meet the challenges of synthetic biology</h4> </div></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-26 fusion-flex-column" style="--awb-bg-size:cover;--awb-width-large:10%;--awb-margin-top-large:0px;--awb-spacing-right-large:19.2%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:19.2%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-27 fusion_builder_column_1_1 1_1 fusion-flex-column" style="--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:1.92%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"><div class="fusion-modal modal fade modal-1 ecco" tabindex="-1" role="dialog" aria-labelledby="modal-heading-1" aria-hidden="true" style="--awb-border-color:#ebebeb;--awb-background:hsla(var(--awb-color8-h),var(--awb-color8-s),calc( var(--awb-color8-l) + 96% ),var(--awb-color8-a));"><div class="modal-dialog modal-lg" role="document"><div class="modal-content fusion-modal-content"><div class="modal-header"><button class="close" type="button" data-dismiss="modal" aria-hidden="true" aria-label="Close">×</button><h3 class="modal-title" id="modal-heading-1" data-dismiss="modal" aria-hidden="true">ECCO: Evolutionary Cellular Computing for Environmental Synthetic Biology</h3></div><div class="modal-body fusion-clearfix"> <p>Can evolution be predicted or controlled? At the <strong>ECCO project</strong> we aim to build <strong>genetic circuits</strong> with <strong>designed evolutionary dynamics</strong>. Circuits capable of self-repairing and adapting to changing environments will be applied as intelligent biocontrol and bioremediation agents. This ERC Consolidator Grant builds on the need to design and implement <strong>robust and predictable engineered circuits</strong> that can be applied to <strong>ecological problems</strong>, in which evolution plays a crucial role. This implies not only the development of novel solutions, but also the definition of new problems.</p> </div></div></div></div><div class="fusion-modal modal fade modal-2 emma" tabindex="-1" role="dialog" aria-labelledby="modal-heading-2" aria-hidden="true" style="--awb-border-color:#ebebeb;--awb-background:hsla(var(--awb-color8-h),var(--awb-color8-s),calc( var(--awb-color8-l) + 96% ),var(--awb-color8-a));"><div class="modal-dialog modal-lg" role="document"><div class="modal-content fusion-modal-content"><div class="modal-header"><button class="close" type="button" data-dismiss="modal" aria-hidden="true" aria-label="Close">×</button><h3 class="modal-title" id="modal-heading-2" data-dismiss="modal" aria-hidden="true">EMMA: Engineering multi-functional microbes for plant-related applications</h3></div><div class="modal-body fusion-clearfix"> <p>Many microbes provide <strong>beneficial traits to plants</strong>. From a synthetic biology point of view, it would be ideal to control both the microbes as well as their functions. At the <strong>EMMA</strong> project we aim to <strong>engineer a multi-functional microbe</strong> with as many of those traits as possible. This poses a magnificent challenge: Synthetic Biology for engineering a bacterial chassis, Metabolic Engineering for implementing pathways, and Control Engineering to fine-tune internal workings. We put our research into practice in <strong>rice crops</strong>.</p> </div></div></div></div><div class="fusion-modal modal fade modal-3 context" tabindex="-1" role="dialog" aria-labelledby="modal-heading-3" aria-hidden="true" style="--awb-border-color:#ebebeb;--awb-background:hsla(var(--awb-color8-h),var(--awb-color8-s),calc( var(--awb-color8-l) + 96% ),var(--awb-color8-a));"><div class="modal-dialog modal-lg" role="document"><div class="modal-content fusion-modal-content"><div class="modal-header"><button class="close" type="button" data-dismiss="modal" aria-hidden="true" aria-label="Close">×</button><h3 class="modal-title" id="modal-heading-3" data-dismiss="modal" aria-hidden="true">CONTEXT: Engineering context-aware synthetic biological circuits</h3></div><div class="modal-body fusion-clearfix"> <p>Bacteria are not only a long DNA sequence. However, researchers often build genetic circuits and devices considering DNA alone. Breaking the current reductionist approach in Synthetic Biology requires thinking about the <strong>context</strong> in which different circuits, parts and devices must perform. In the <strong>CONTEXT project </strong>we aim at designing and implementing devices considering genes, their <strong>intra-cellular dependencies</strong> and also <strong>extra-cellular conditions</strong>. Our hypothesis is that embracing complexity may delay the development of a device but will surely expand its scope and power.</p> </div></div></div></div><div class="fusion-modal modal fade modal-4 biosint" tabindex="-1" role="dialog" aria-labelledby="modal-heading-4" aria-hidden="true" style="--awb-border-color:#ebebeb;--awb-background:hsla(var(--awb-color8-h),var(--awb-color8-s),calc( var(--awb-color8-l) + 96% ),var(--awb-color8-a));"><div class="modal-dialog modal-lg" role="document"><div class="modal-content fusion-modal-content"><div class="modal-header"><button class="close" type="button" data-dismiss="modal" aria-hidden="true" aria-label="Close">×</button><h3 class="modal-title" id="modal-heading-4" data-dismiss="modal" aria-hidden="true">BIOSINT- CM: Biología Sintética Tridimensional en Bacterias de BIocontrol Ambiental</h3></div><div class="modal-body fusion-clearfix"> <p>In electronic circuits, position is not an issue because connections between components are unique. In a cell, however, the position of circuit parts should not be ignored. <strong>Spatial engineering </strong>is a central topic at our laboratory. The <strong>BIOSINT-CM</strong> project studies several <strong>spatial features</strong>, such us where genes and proteins should be located or whether transcription and translation are coupled or not, to <strong>improve circuit performance</strong> and achieve the best results.</p> </div></div></div></div><div class="fusion-modal modal fade modal-5 multi" tabindex="-1" role="dialog" aria-labelledby="modal-heading-5" aria-hidden="true" style="--awb-border-color:#ebebeb;--awb-background:hsla(var(--awb-color8-h),var(--awb-color8-s),calc( var(--awb-color8-l) + 96% ),var(--awb-color8-a));"><div class="modal-dialog modal-lg" role="document"><div class="modal-content fusion-modal-content"><div class="modal-header"><button class="close" type="button" data-dismiss="modal" aria-hidden="true" aria-label="Close">×</button><h3 class="modal-title" id="modal-heading-5" data-dismiss="modal" aria-hidden="true">MULTI-SYSBIO: Implementing social relationships in synthetic multicellular systems to achieve robust and reliable biocomputations</h3></div><div class="modal-body fusion-clearfix"> <p>The way bacteria communicate can be engineered, so <strong>programming </strong>can be done for<strong> a multi-strain</strong> consortium, not only for individual cells. The <strong>MULTI-SYSBIO</strong> project aims to develop <strong>multicellular architectures</strong> that facilitate engineering efforts—such as the development of single-cell chassis—but for consortia.</p> </div></div></div></div><div class="fusion-modal modal fade modal-6 multi2" tabindex="-1" role="dialog" aria-labelledby="modal-heading-6" aria-hidden="true" style="--awb-border-color:#ebebeb;--awb-background:hsla(var(--awb-color8-h),var(--awb-color8-s),calc( var(--awb-color8-l) + 96% ),var(--awb-color8-a));"><div class="modal-dialog modal-lg" role="document"><div class="modal-content fusion-modal-content"><div class="modal-header"><button class="close" type="button" data-dismiss="modal" aria-hidden="true" aria-label="Close">×</button><h3 class="modal-title" id="modal-heading-6" data-dismiss="modal" aria-hidden="true">MULTI-SYNBIO: Increasing the efficiency of multicellular synthetic consortia for biocomputing via implementing pre-defined conjugation dynamics</h3></div><div class="modal-body fusion-clearfix"> <p>By using <strong>bacterial conjugation</strong> as a messaging protocol, MULTI-SYNBIO aims to implement <strong>synthetic multicellular consortia</strong> with unprecedented computing capabilities. <strong>Entire genetic circuits</strong> encoded in plasmid vectors will<strong> travel between cells</strong> and throughout the population.</p> </div></div></div></div><div class="fusion-modal modal fade modal-7 electric" tabindex="-1" role="dialog" aria-labelledby="modal-heading-7" aria-hidden="true" style="--awb-border-color:#ebebeb;--awb-background:hsla(var(--awb-color8-h),var(--awb-color8-s),calc( var(--awb-color8-l) + 96% ),var(--awb-color8-a));"><div class="modal-dialog modal-lg" role="document"><div class="modal-content fusion-modal-content"><div class="modal-header"><button class="close" type="button" data-dismiss="modal" aria-hidden="true" aria-label="Close">×</button><h3 class="modal-title" id="modal-heading-7" data-dismiss="modal" aria-hidden="true">BIOELECTRIC: Synthetic biological systems with electronic control</h3></div><div class="modal-body fusion-clearfix"> <p><strong>BIOELECTRIC</strong> will develop our current line of research into how we can use electricity to interact with genetic networks – and vice versa. The intersection of <strong>electric and genetic signals</strong> will facilitate the use of Synthetic Biology in <strong>application domains that are unreachable</strong> to current strategies and methodologies.</p> </div></div></div></div><div class="fusion-modal modal fade modal-8 bioroboost" tabindex="-1" role="dialog" aria-labelledby="modal-heading-8" aria-hidden="true" style="--awb-border-color:#ebebeb;--awb-background:hsla(var(--awb-color8-h),var(--awb-color8-s),calc( var(--awb-color8-l) + 96% ),var(--awb-color8-a));"><div class="modal-dialog modal-lg" role="document"><div class="modal-content fusion-modal-content"><div class="modal-header"><button class="close" type="button" data-dismiss="modal" aria-hidden="true" aria-label="Close">×</button><h3 class="modal-title" id="modal-heading-8" data-dismiss="modal" aria-hidden="true">BioRoboost: Fostering Synthetic Biology standardisation through international collaboration</h3></div><div class="modal-body fusion-clearfix"> <p>Although Synthetic Biology claims to be an engineering discipline, it lacks the level of <strong>standardisation</strong> of other engineering fields, which rely on the use of well-defined, universal, and robust standard components. In <strong>BioRoboost,</strong> more than 25 Synthetic Biology laboratories joined forces to tackle this issue. The project looked into biological standards, information standards, robust measurements and characterisations, as well as cultural issues that may impact the <strong>adoption of standard methods and techniques </strong>by scientists.</p> </div></div></div></div><div class="fusion-modal modal fade modal-9 synbio" tabindex="-1" role="dialog" aria-labelledby="modal-heading-9" aria-hidden="true" style="--awb-border-color:#ebebeb;--awb-background:hsla(var(--awb-color8-h),var(--awb-color8-s),calc( var(--awb-color8-l) + 96% ),var(--awb-color8-a));"><div class="modal-dialog modal-lg" role="document"><div class="modal-content fusion-modal-content"><div class="modal-header"><button class="close" type="button" data-dismiss="modal" aria-hidden="true" aria-label="Close">×</button><h3 class="modal-title" id="modal-heading-9" data-dismiss="modal" aria-hidden="true">SynBio3D: Establishing the engineering fundamentals of three-dimensional synthetic biology</h3></div><div class="modal-body fusion-clearfix"> <p>It is not only the DNA sequence of a given part, but also its positioning within the 3D volume of the cell that is responsible for its performance. Therefore, the <strong>spatial arrangement</strong> of a regulatory circuit is a central design principle. The <strong>SynBio3D</strong> project dealt with the modelling of gene regulation kinetics that included <strong>distance-specific dynamics</strong>, like transcription factor sliding, hopping and diffusing.</p> </div></div></div></div></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-28 fusion_builder_column_1_3 1_3 fusion-flex-column fusion-flex-align-self-stretch fusion-animated" style="--awb-padding-right:6%;--awb-padding-bottom:10%;--awb-padding-left:6%;--awb-overflow:hidden;--awb-bg-color:var(--awb-color1);--awb-bg-color-hover:var(--awb-color1);--awb-bg-size:cover;--awb-border-radius:20px 20px 20px 20px;--awb-width-large:33.333333333333%;--awb-margin-top-large:0px;--awb-spacing-right-large:5.76%;--awb-margin-bottom-large:4%;--awb-spacing-left-large:5.76%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-margin-bottom-small:6%;--awb-spacing-left-small:1.92%;" data-animationType="fadeInUp" data-animationDuration="1.3" data-animationOffset="top-into-view"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-space-between fusion-content-layout-column"><div class="fusion-image-element " style="text-align:center;--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);"><span class=" fusion-imageframe imageframe-none imageframe-5 hover-type-none"><img decoding="async" width="1251" height="1250" alt="ECCO_project" src="https://biocomputationlab.com/wp-content/uploads/2022/05/project_-02.png" data-orig-src="https://biocomputationlab.com/wp-content/uploads/2022/05/project_-02.png" class="lazyload img-responsive wp-image-5278" srcset="data:image/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%271251%27%20height%3D%271250%27%20viewBox%3D%270%200%201251%201250%27%3E%3Crect%20width%3D%271251%27%20height%3D%271250%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E" data-srcset="https://biocomputationlab.com/wp-content/uploads/2022/05/project_-02-200x200.png 200w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-02-400x400.png 400w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-02-600x600.png 600w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-02-800x799.png 800w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-02-1200x1199.png 1200w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-02.png 1251w" data-sizes="auto" data-orig-sizes="(max-width: 1024px) 100vw, (max-width: 640px) 100vw, 400px" /></span></div><div class="fusion-text fusion-text-19 fusion-text-no-margin" style="--awb-margin-bottom:-11%;"><h5 style="text-align: center;">ECCO: Evolutionary Cellular Computing for Environmental Synthetic Biology</h5> </div><div class="fusion-text fusion-text-20"><ul style="font-size: 17px;"> <li><strong>Duration</strong>: Oct 2022 – Sep 2027.</li> <li><strong>Funding body</strong>: European Research Council (ERC Consolidator Grant).</li> <li><strong>Project number</strong>: 101044360</li> </ul> </div><div style="text-align:center;"><a class="fusion-button button-flat fusion-button-default-size button-default fusion-button-default button-1 fusion-button-default-span fusion-button-default-type" style="--button_margin-top:6%;" target="_self" href="#" data-toggle="modal" data-target=".fusion-modal.ecco"><span class="fusion-button-text">DISCOVER MORE</span></a></div></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-29 fusion_builder_column_1_3 1_3 fusion-flex-column fusion-flex-align-self-stretch fusion-animated" style="--awb-padding-right:6%;--awb-padding-bottom:10%;--awb-padding-left:6%;--awb-overflow:hidden;--awb-bg-color:var(--awb-color1);--awb-bg-color-hover:var(--awb-color1);--awb-bg-size:cover;--awb-border-radius:20px 20px 20px 20px;--awb-width-large:33.333333333333%;--awb-margin-top-large:0px;--awb-spacing-right-large:5.76%;--awb-margin-bottom-large:4%;--awb-spacing-left-large:5.76%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-margin-bottom-small:6%;--awb-spacing-left-small:1.92%;" data-animationType="fadeInUp" data-animationDuration="1.3" data-animationOffset="top-into-view"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-space-between fusion-content-layout-column"><div class="fusion-image-element " style="text-align:center;--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);"><span class=" fusion-imageframe imageframe-none imageframe-6 hover-type-none"><img decoding="async" width="1251" height="1251" alt="BIOSINT_project" src="https://biocomputationlab.com/wp-content/uploads/2022/05/project_-06.png" data-orig-src="https://biocomputationlab.com/wp-content/uploads/2022/05/project_-06.png" class="lazyload img-responsive wp-image-5282" srcset="data:image/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%271251%27%20height%3D%271251%27%20viewBox%3D%270%200%201251%201251%27%3E%3Crect%20width%3D%271251%27%20height%3D%271251%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E" data-srcset="https://biocomputationlab.com/wp-content/uploads/2022/05/project_-06-200x200.png 200w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-06-400x400.png 400w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-06-600x600.png 600w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-06-800x800.png 800w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-06-1200x1200.png 1200w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-06.png 1251w" data-sizes="auto" data-orig-sizes="(max-width: 1024px) 100vw, (max-width: 640px) 100vw, 400px" /></span></div><div class="fusion-text fusion-text-21 fusion-text-no-margin" style="--awb-margin-bottom:-11%;"><h5 style="text-align: center;">BIOSINT- CM: Biología Sintética Tridimensional en Bacterias de BIocontrol Ambiental</h5> </div><div class="fusion-text fusion-text-22"><ul style="font-size: 17px;"> <li><strong>Duration</strong>: July 2021 – Dec 2024.</li> <li><strong>Funding body</strong>: Comunidad de Madrid.</li> <li><strong>Project number: </strong>Y2020/TCS-6555</li> </ul> </div><div style="text-align:center;"><a class="fusion-button button-flat fusion-button-default-size button-default fusion-button-default button-2 fusion-button-default-span fusion-button-default-type" style="--button_margin-top:6%;" target="_self" href="#" data-toggle="modal" data-target=".fusion-modal.biosint"><span class="fusion-button-text">DISCOVER MORE</span></a></div></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-30 fusion_builder_column_1_3 1_3 fusion-flex-column fusion-flex-align-self-stretch fusion-animated" style="--awb-padding-right:6%;--awb-padding-bottom:10%;--awb-padding-left:6%;--awb-overflow:hidden;--awb-bg-color:var(--awb-color1);--awb-bg-color-hover:var(--awb-color1);--awb-bg-size:cover;--awb-border-radius:20px 20px 20px 20px;--awb-width-large:33.333333333333%;--awb-margin-top-large:0px;--awb-spacing-right-large:5.76%;--awb-margin-bottom-large:4%;--awb-spacing-left-large:5.76%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-margin-bottom-small:6%;--awb-spacing-left-small:1.92%;" data-animationType="fadeInUp" data-animationDuration="1.3" data-animationOffset="top-into-view"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-space-between fusion-content-layout-column"><div class="fusion-image-element " style="text-align:center;--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);"><span class=" fusion-imageframe imageframe-none imageframe-7 hover-type-none"><img decoding="async" width="1251" height="1250" alt="MULTI SYSBIO_project" src="https://biocomputationlab.com/wp-content/uploads/2022/05/project_-03.png" data-orig-src="https://biocomputationlab.com/wp-content/uploads/2022/05/project_-03.png" class="lazyload img-responsive wp-image-5283" srcset="data:image/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%271251%27%20height%3D%271250%27%20viewBox%3D%270%200%201251%201250%27%3E%3Crect%20width%3D%271251%27%20height%3D%271250%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E" data-srcset="https://biocomputationlab.com/wp-content/uploads/2022/05/project_-03-200x200.png 200w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-03-400x400.png 400w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-03-600x600.png 600w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-03-800x799.png 800w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-03-1200x1199.png 1200w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-03.png 1251w" data-sizes="auto" data-orig-sizes="(max-width: 1024px) 100vw, (max-width: 640px) 100vw, 400px" /></span></div><div class="fusion-text fusion-text-23 fusion-text-no-margin" style="--awb-margin-bottom:-11%;"><h5 style="text-align: center;">MULTI-SYSBIO: Implementing social relationships in synthetic multicellular systems to achieve robust and reliable biocomputations</h5> </div><div class="fusion-text fusion-text-24"><ul style="font-size: 17px;"> <li><strong>Duration</strong>: Sep 2021 – Sep 2024.</li> <li><strong>Funding body</strong>: Ministerio de Ciencia – Agencia Estatal de Investigación.</li> <li><strong>Project number: </strong>PID2020-117205GA-I00</li> </ul> </div><div style="text-align:center;"><a class="fusion-button button-flat fusion-button-default-size button-default fusion-button-default button-3 fusion-button-default-span fusion-button-default-type" style="--button_margin-top:6%;" target="_self" href="#" data-toggle="modal" data-target=".fusion-modal.multi"><span class="fusion-button-text">DISCOVER MORE</span></a></div></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-31 fusion_builder_column_1_6 1_6 fusion-flex-column" style="--awb-bg-size:cover;--awb-width-large:16.666666666667%;--awb-margin-top-large:0px;--awb-spacing-right-large:11.52%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:11.52%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-32 fusion_builder_column_1_3 1_3 fusion-flex-column fusion-flex-align-self-stretch fusion-animated" style="--awb-padding-right:6%;--awb-padding-bottom:10%;--awb-padding-left:6%;--awb-overflow:hidden;--awb-bg-color:var(--awb-color1);--awb-bg-color-hover:var(--awb-color1);--awb-bg-size:cover;--awb-border-radius:20px 20px 20px 20px;--awb-width-large:33.333333333333%;--awb-margin-top-large:0px;--awb-spacing-right-large:5.76%;--awb-margin-bottom-large:4%;--awb-spacing-left-large:5.76%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-margin-bottom-small:6%;--awb-spacing-left-small:1.92%;" data-animationType="fadeInUp" data-animationDuration="1.3" data-animationOffset="top-into-view"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-space-between fusion-content-layout-column"><div class="fusion-image-element " style="text-align:center;--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);"><span class=" fusion-imageframe imageframe-none imageframe-8 hover-type-none"><img decoding="async" width="300" height="281" title="MULTISYNBIO" src="https://biocomputationlab.com/wp-content/uploads/2024/11/MULTISYNBIO.png" data-orig-src="https://biocomputationlab.com/wp-content/uploads/2024/11/MULTISYNBIO-300x281.png" alt class="lazyload img-responsive wp-image-5697" srcset="data:image/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%272344%27%20height%3D%272193%27%20viewBox%3D%270%200%202344%202193%27%3E%3Crect%20width%3D%272344%27%20height%3D%272193%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E" data-srcset="https://biocomputationlab.com/wp-content/uploads/2024/11/MULTISYNBIO-200x187.png 200w, https://biocomputationlab.com/wp-content/uploads/2024/11/MULTISYNBIO-400x374.png 400w, https://biocomputationlab.com/wp-content/uploads/2024/11/MULTISYNBIO-600x561.png 600w, https://biocomputationlab.com/wp-content/uploads/2024/11/MULTISYNBIO-800x748.png 800w, https://biocomputationlab.com/wp-content/uploads/2024/11/MULTISYNBIO-1200x1123.png 1200w" data-sizes="auto" data-orig-sizes="(max-width: 1024px) 100vw, (max-width: 640px) 100vw, 400px" /></span></div><div class="fusion-text fusion-text-25 fusion-text-no-margin" style="--awb-margin-bottom:-11%;"><h5 style="text-align: center;">MULTI-SYNBIO: Increasing the efficiency of multicellular synthetic<br /> consortia for biocomputing via implementing pre-defined conjugation dynamics</h5> </div><div class="fusion-text fusion-text-26"><ul style="font-size: 17px;"> <li><strong>Duration</strong>: Sep 2024 – Sep 2027.</li> <li><strong>Funding body</strong>: Ministerio de Ciencia – Agencia Estatal de Investigación.</li> <li><strong>Project number:</strong>PID2023-152470NB-I00<strong><br /> </strong></li> </ul> </div><div style="text-align:center;"><a class="fusion-button button-flat fusion-button-default-size button-default fusion-button-default button-4 fusion-button-default-span fusion-button-default-type" style="--button_margin-top:6%;" target="_self" href="#" data-toggle="modal" data-target=".fusion-modal.multi2"><span class="fusion-button-text">DISCOVER MORE</span></a></div></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-33 fusion_builder_column_1_3 1_3 fusion-flex-column fusion-flex-align-self-stretch fusion-animated" style="--awb-padding-right:6%;--awb-padding-bottom:10%;--awb-padding-left:6%;--awb-overflow:hidden;--awb-bg-color:var(--awb-color1);--awb-bg-color-hover:var(--awb-color1);--awb-bg-size:cover;--awb-border-radius:20px 20px 20px 20px;--awb-width-large:33.333333333333%;--awb-margin-top-large:0px;--awb-spacing-right-large:5.76%;--awb-margin-bottom-large:4%;--awb-spacing-left-large:5.76%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-margin-bottom-small:6%;--awb-spacing-left-small:1.92%;" data-animationType="fadeInUp" data-animationDuration="1.3" data-animationOffset="top-into-view"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-space-between fusion-content-layout-column"><div class="fusion-image-element " style="text-align:center;--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);"><span class=" fusion-imageframe imageframe-none imageframe-9 hover-type-none"><img decoding="async" width="300" height="236" title="BIOELECTRIC" src="https://biocomputationlab.com/wp-content/uploads/2024/11/BIOELECTRIC.png" data-orig-src="https://biocomputationlab.com/wp-content/uploads/2024/11/BIOELECTRIC-300x236.png" alt class="lazyload img-responsive wp-image-5695" srcset="data:image/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%273501%27%20height%3D%272759%27%20viewBox%3D%270%200%203501%202759%27%3E%3Crect%20width%3D%273501%27%20height%3D%272759%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E" data-srcset="https://biocomputationlab.com/wp-content/uploads/2024/11/BIOELECTRIC-200x158.png 200w, https://biocomputationlab.com/wp-content/uploads/2024/11/BIOELECTRIC-400x315.png 400w, https://biocomputationlab.com/wp-content/uploads/2024/11/BIOELECTRIC-600x473.png 600w, https://biocomputationlab.com/wp-content/uploads/2024/11/BIOELECTRIC-800x630.png 800w, https://biocomputationlab.com/wp-content/uploads/2024/11/BIOELECTRIC-1200x946.png 1200w" data-sizes="auto" data-orig-sizes="(max-width: 1024px) 100vw, (max-width: 640px) 100vw, 400px" /></span></div><div class="fusion-text fusion-text-27 fusion-text-no-margin" style="--awb-margin-bottom:-11%;"><h5 style="text-align: center;">BIOELECTRIC: Synthetic biological systems with electronic control</h5> </div><div class="fusion-text fusion-text-28"><ul style="font-size: 17px;"> <li><strong>Duration</strong>: Sep 2023 – Sep 2025.</li> <li><strong>Funding body</strong>: Ministerio de Ciencia – Agencia Estatal de Investigación.</li> <li><strong>Project number: </strong>CNS2022-135951</li> </ul> </div><div style="text-align:center;"><a class="fusion-button button-flat fusion-button-default-size button-default fusion-button-default button-5 fusion-button-default-span fusion-button-default-type" style="--button_margin-top:6%;" target="_self" href="#" data-toggle="modal" data-target=".fusion-modal.electric"><span class="fusion-button-text">DISCOVER MORE</span></a></div></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-34 fusion_builder_column_1_6 1_6 fusion-flex-column" style="--awb-bg-size:cover;--awb-width-large:16.666666666667%;--awb-margin-top-large:0px;--awb-spacing-right-large:11.52%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:11.52%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"></div></div></div></div></div><div id="finished-projects" class="fusion-container-anchor"><div class="fusion-fullwidth fullwidth-box fusion-builder-row-4 fusion-flex-container fusion-parallax-none nonhundred-percent-fullwidth non-hundred-percent-height-scrolling lazyload" style="--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:4%;--awb-padding-bottom:5%;--awb-padding-bottom-small:4%;--awb-background-color:var(--awb-color2);--awb-background-size:cover;--awb-flex-wrap:wrap;" data-bg="https://biocomputationlab.com/wp-content/uploads/2022/05/details_v3.png" ><div class="fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap" style="max-width:1216.8px;margin-left: calc(-4% / 2 );margin-right: calc(-4% / 2 );"><div class="fusion-layout-column fusion_builder_column fusion-builder-column-35 fusion-flex-column" style="--awb-bg-size:cover;--awb-width-large:10%;--awb-margin-top-large:0px;--awb-spacing-right-large:19.2%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:19.2%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-36 fusion_builder_column_4_5 4_5 fusion-flex-column fusion-animated" style="--awb-bg-size:cover;--awb-width-large:80%;--awb-margin-top-large:0px;--awb-spacing-right-large:2.4%;--awb-margin-bottom-large:4%;--awb-spacing-left-large:2.4%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;" data-animationType="fadeInUp" data-animationDuration="1.3" data-animationOffset="top-into-view"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"><div class="fusion-menu-anchor" id="finished-projects"></div><div class="fusion-text fusion-text-29"><h3 style="text-align: center;">Finished projects</h3> </div><div class="fusion-text fusion-text-30"><h4 style="text-align: center;">Explore our past research</h4> </div></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-37 fusion-flex-column fusion-no-small-visibility" style="--awb-bg-size:cover;--awb-width-large:10%;--awb-margin-top-large:0px;--awb-spacing-right-large:19.2%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:19.2%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-38 fusion_builder_column_1_3 1_3 fusion-flex-column fusion-flex-align-self-stretch fusion-animated" style="--awb-padding-right:6%;--awb-padding-bottom:10%;--awb-padding-left:6%;--awb-overflow:hidden;--awb-bg-color:var(--awb-color1);--awb-bg-color-hover:var(--awb-color1);--awb-bg-size:cover;--awb-box-shadow:3px 3px 15px -3px rgba(55,73,62,0.27);;--awb-border-radius:20px 20px 20px 20px;--awb-width-large:33.333333333333%;--awb-margin-top-large:0px;--awb-spacing-right-large:5.76%;--awb-margin-bottom-large:4%;--awb-spacing-left-large:5.76%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-margin-bottom-small:6%;--awb-spacing-left-small:1.92%;" data-animationType="fadeInUp" data-animationDuration="1.3" data-animationOffset="top-into-view"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-space-between fusion-content-layout-column"><div class="fusion-image-element " style="text-align:center;--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);"><span class=" fusion-imageframe imageframe-none imageframe-10 hover-type-none"><img decoding="async" width="1250" height="1250" src="https://biocomputationlab.com/wp-content/uploads/2022/05/project_-01.png" data-orig-src="https://biocomputationlab.com/wp-content/uploads/2022/05/project_-01.png" alt class="lazyload img-responsive wp-image-5285" srcset="data:image/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%271250%27%20height%3D%271250%27%20viewBox%3D%270%200%201250%201250%27%3E%3Crect%20width%3D%271250%27%20height%3D%271250%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E" data-srcset="https://biocomputationlab.com/wp-content/uploads/2022/05/project_-01-200x200.png 200w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-01-400x400.png 400w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-01-600x600.png 600w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-01-800x800.png 800w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-01-1200x1200.png 1200w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-01.png 1250w" data-sizes="auto" data-orig-sizes="(max-width: 1024px) 100vw, (max-width: 640px) 100vw, 400px" /></span></div><div class="fusion-text fusion-text-31 fusion-text-no-margin" style="--awb-margin-bottom:-11%;"><h5 style="text-align: center;">Fostering Synthetic Biology standardisation through international collaboration</h5> </div><div class="fusion-text fusion-text-32"><ul style="font-size: 17px;"> <li><strong>Duration</strong>: Sep 2018 – Sep 2021.</li> <li><strong>Funding body</strong>: European Commission (H2020).</li> <li><strong>Project number: </strong>820699</li> </ul> </div><div style="text-align:center;"><a class="fusion-button button-flat fusion-button-default-size button-default fusion-button-default button-6 fusion-button-default-span fusion-button-default-type" style="--button_margin-top:6%;" target="_self" href="#" data-toggle="modal" data-target=".fusion-modal.bioroboost"><span class="fusion-button-text">DISCOVER MORE</span></a></div></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-39 fusion_builder_column_1_3 1_3 fusion-flex-column fusion-flex-align-self-stretch fusion-animated" style="--awb-padding-right:6%;--awb-padding-bottom:10%;--awb-padding-left:6%;--awb-overflow:hidden;--awb-bg-color:var(--awb-color1);--awb-bg-color-hover:var(--awb-color1);--awb-bg-size:cover;--awb-border-radius:20px 20px 20px 20px;--awb-width-large:33.333333333333%;--awb-margin-top-large:0px;--awb-spacing-right-large:5.76%;--awb-margin-bottom-large:4%;--awb-spacing-left-large:5.76%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-margin-bottom-small:6%;--awb-spacing-left-small:1.92%;" data-animationType="fadeInUp" data-animationDuration="1.3" data-animationOffset="top-into-view"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-space-between fusion-content-layout-column"><div class="fusion-image-element " style="text-align:center;--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);"><span class=" fusion-imageframe imageframe-none imageframe-11 hover-type-none"><img decoding="async" width="1251" height="1251" alt="CONTEXT_project" src="https://biocomputationlab.com/wp-content/uploads/2022/05/project_-07.png" data-orig-src="https://biocomputationlab.com/wp-content/uploads/2022/05/project_-07.png" class="lazyload img-responsive wp-image-5280" srcset="data:image/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%271251%27%20height%3D%271251%27%20viewBox%3D%270%200%201251%201251%27%3E%3Crect%20width%3D%271251%27%20height%3D%271251%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E" data-srcset="https://biocomputationlab.com/wp-content/uploads/2022/05/project_-07-200x200.png 200w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-07-400x400.png 400w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-07-600x600.png 600w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-07-800x800.png 800w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-07-1200x1200.png 1200w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-07.png 1251w" data-sizes="auto" data-orig-sizes="(max-width: 1024px) 100vw, (max-width: 640px) 100vw, 400px" /></span></div><div class="fusion-text fusion-text-33 fusion-text-no-margin" style="--awb-margin-bottom:-11%;"><h5 style="text-align: center;">CONTEXT: Engineering context-aware synthetic biological circuits</h5> </div><div class="fusion-text fusion-text-34"><ul style="font-size: 17px;"> <li><strong>Duration</strong>: Sep 2020 – Sep 2024.</li> <li><strong>Funding body</strong>: Comunidad de Madrid.</li> <li><strong>Project number:</strong> 2019-T1/BIO-14053</li> </ul> </div><div style="text-align:center;"><a class="fusion-button button-flat fusion-button-default-size button-default fusion-button-default button-7 fusion-button-default-span fusion-button-default-type" style="--button_margin-top:6%;" target="_self" href="#" data-toggle="modal" data-target=".fusion-modal.context"><span class="fusion-button-text">DISCOVER MORE</span></a></div></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-40 fusion_builder_column_1_3 1_3 fusion-flex-column fusion-flex-align-self-stretch fusion-animated" style="--awb-padding-right:6%;--awb-padding-bottom:10%;--awb-padding-left:6%;--awb-overflow:hidden;--awb-bg-color:var(--awb-color1);--awb-bg-color-hover:var(--awb-color1);--awb-bg-size:cover;--awb-border-radius:20px 20px 20px 20px;--awb-width-large:33.333333333333%;--awb-margin-top-large:0px;--awb-spacing-right-large:5.76%;--awb-margin-bottom-large:4%;--awb-spacing-left-large:5.76%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-margin-bottom-small:6%;--awb-spacing-left-small:1.92%;" data-animationType="fadeInUp" data-animationDuration="1.3" data-animationOffset="top-into-view"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-space-between fusion-content-layout-column"><div class="fusion-image-element " style="text-align:center;--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);"><span class=" fusion-imageframe imageframe-none imageframe-12 hover-type-none"><img decoding="async" width="1250" height="1251" alt="EMMA_project" src="https://biocomputationlab.com/wp-content/uploads/2022/05/project_-05.png" data-orig-src="https://biocomputationlab.com/wp-content/uploads/2022/05/project_-05.png" class="lazyload img-responsive wp-image-5279" srcset="data:image/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%271250%27%20height%3D%271251%27%20viewBox%3D%270%200%201250%201251%27%3E%3Crect%20width%3D%271250%27%20height%3D%271251%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E" data-srcset="https://biocomputationlab.com/wp-content/uploads/2022/05/project_-05-200x200.png 200w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-05-400x400.png 400w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-05-600x600.png 600w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-05-800x801.png 800w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-05-1200x1201.png 1200w, https://biocomputationlab.com/wp-content/uploads/2022/05/project_-05.png 1250w" data-sizes="auto" data-orig-sizes="(max-width: 1024px) 100vw, (max-width: 640px) 100vw, 400px" /></span></div><div class="fusion-text fusion-text-35 fusion-text-no-margin" style="--awb-margin-bottom:-11%;"><h5 style="text-align: center;">EMMA: Engineering multi-functional microbes for plant-related applications</h5> </div><div class="fusion-text fusion-text-36"><ul style="font-size: 17px;"> <li><strong>Duration</strong>: Sep 2022 – Dec 2024.</li> <li><strong>Funding body</strong>: Ministerio de Ciencia / Agencia Estatal de Investigación as part of the Severo Ochoa programme with code CEX2020-000999-S</li> </ul> </div><div style="text-align:center;"><a class="fusion-button button-flat fusion-button-default-size button-default fusion-button-default button-8 fusion-button-default-span fusion-button-default-type" style="--button_margin-top:6%;" target="_self" href="#" data-toggle="modal" data-target=".fusion-modal.emma"><span class="fusion-button-text">DISCOVER MORE</span></a></div></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-41 fusion_builder_column_1_3 1_3 fusion-flex-column" style="--awb-bg-size:cover;--awb-width-large:33.333333333333%;--awb-margin-top-large:0px;--awb-spacing-right-large:5.76%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:5.76%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column"></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-42 fusion_builder_column_1_3 1_3 fusion-flex-column fusion-flex-align-self-stretch fusion-animated" style="--awb-padding-right:6%;--awb-padding-bottom:10%;--awb-padding-left:6%;--awb-overflow:hidden;--awb-bg-color:var(--awb-color1);--awb-bg-color-hover:var(--awb-color1);--awb-bg-size:cover;--awb-box-shadow:3px 3px 15px -3px rgba(55,73,62,0.27);;--awb-border-radius:20px 20px 20px 20px;--awb-width-large:33.333333333333%;--awb-margin-top-large:0px;--awb-spacing-right-large:5.76%;--awb-margin-bottom-large:4%;--awb-spacing-left-large:5.76%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;" data-animationType="fadeInUp" data-animationDuration="1.3" data-animationOffset="top-into-view"><div class="fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-space-between fusion-content-layout-column"><div class="fusion-image-element " style="text-align:center;--awb-max-width:90%;--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);"><span class=" fusion-imageframe imageframe-none imageframe-13 hover-type-none"><img decoding="async" width="1251" height="1250" alt="SynBio_project" src="https://biocomputationlab.com/wp-content/uploads/2022/05/project_-04.png" data-orig-src="https://biocomputationlab.com/wp-content/uploads/2022/05/project_-04.png" class="lazyload img-responsive wp-image-5286" 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style="--awb-margin-bottom:-11%;"><h5 style="text-align: center;">SynBio3D: Establishing the engineering fundamentals of three-dimensional synthetic biology</h5> </div><div class="fusion-text fusion-text-38"><ul style="font-size: 17px;"> <li><strong>Duration</strong>: Feb 2018 – Aug 2020.</li> <li><strong>Funding body</strong>: Engineering and Physical Sciences Research Council (EPSRC).</li> <li><strong>Project number: </strong>EP/R019002/1</li> </ul> </div><div style="text-align:center;"><a class="fusion-button button-flat fusion-button-default-size button-default fusion-button-default button-9 fusion-button-default-span fusion-button-default-type" style="--button_margin-top:6%;" target="_self" href="#" data-toggle="modal" data-target=".fusion-modal.synbio"><span class="fusion-button-text">DISCOVER MORE</span></a></div></div></div><div class="fusion-layout-column fusion_builder_column fusion-builder-column-43 fusion_builder_column_1_3 1_3 fusion-flex-column" 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