CINXE.COM

<!DOCTYPE html> <html class="client-nojs vector-feature-language-in-header-enabled vector-feature-language-in-main-page-header-disabled vector-feature-page-tools-pinned-disabled vector-feature-toc-pinned-clientpref-1 vector-feature-main-menu-pinned-disabled vector-feature-limited-width-clientpref-1 vector-feature-limited-width-content-enabled vector-feature-custom-font-size-clientpref-1 vector-feature-appearance-pinned-clientpref-1 vector-feature-night-mode-enabled skin-theme-clientpref-day vector-sticky-header-enabled vector-toc-available" lang="en" dir="ltr"> <head> <meta charset="UTF-8"> <title>Integrin alpha L - Wikipedia</title> <script>(function(){var className="client-js vector-feature-language-in-header-enabled vector-feature-language-in-main-page-header-disabled vector-feature-page-tools-pinned-disabled vector-feature-toc-pinned-clientpref-1 vector-feature-main-menu-pinned-disabled vector-feature-limited-width-clientpref-1 vector-feature-limited-width-content-enabled vector-feature-custom-font-size-clientpref-1 vector-feature-appearance-pinned-clientpref-1 vector-feature-night-mode-enabled skin-theme-clientpref-day vector-sticky-header-enabled vector-toc-available";var cookie=document.cookie.match(/(?:^|; )enwikimwclientpreferences=([^;]+)/);if(cookie){cookie[1].split('%2C').forEach(function(pref){className=className.replace(new RegExp('(^| )'+pref.replace(/-clientpref-\w+$|[^\w-]+/g,'')+'-clientpref-\\w+( |$)'),'$1'+pref+'$2');});}document.documentElement.className=className;}());RLCONF={"wgBreakFrames":false,"wgSeparatorTransformTable":["",""],"wgDigitTransformTable":["",""],"wgDefaultDateFormat":"dmy", "wgMonthNames":["","January","February","March","April","May","June","July","August","September","October","November","December"],"wgRequestId":"4e1b4512-500f-461a-b98e-9b9b105d03a2","wgCanonicalNamespace":"","wgCanonicalSpecialPageName":false,"wgNamespaceNumber":0,"wgPageName":"Integrin_alpha_L","wgTitle":"Integrin alpha L","wgCurRevisionId":1228262317,"wgRevisionId":1228262317,"wgArticleId":5874177,"wgIsArticle":true,"wgIsRedirect":false,"wgAction":"view","wgUserName":null,"wgUserGroups":["*"],"wgCategories":["Articles with short description","Short description matches Wikidata","Webarchive template wayback links","All stub articles","Genes on human chromosome 16","Integrins","Clusters of differentiation","Human chromosome 16 gene stubs"],"wgPageViewLanguage":"en","wgPageContentLanguage":"en","wgPageContentModel":"wikitext","wgRelevantPageName":"Integrin_alpha_L","wgRelevantArticleId":5874177,"wgIsProbablyEditable":true,"wgRelevantPageIsProbablyEditable":true,"wgRestrictionEdit":[], "wgRestrictionMove":[],"wgRedirectedFrom":"CD11a","wgNoticeProject":"wikipedia","wgCiteReferencePreviewsActive":false,"wgFlaggedRevsParams":{"tags":{"status":{"levels":1}}},"wgMediaViewerOnClick":true,"wgMediaViewerEnabledByDefault":true,"wgPopupsFlags":0,"wgVisualEditor":{"pageLanguageCode":"en","pageLanguageDir":"ltr","pageVariantFallbacks":"en"},"wgMFDisplayWikibaseDescriptions":{"search":true,"watchlist":true,"tagline":false,"nearby":true},"wgWMESchemaEditAttemptStepOversample":false,"wgWMEPageLength":10000,"wgInternalRedirectTargetUrl":"/wiki/Integrin_alpha_L","wgEditSubmitButtonLabelPublish":true,"wgULSPosition":"interlanguage","wgULSisCompactLinksEnabled":false,"wgVector2022LanguageInHeader":true,"wgULSisLanguageSelectorEmpty":false,"wgWikibaseItemId":"Q3648604","wgCheckUserClientHintsHeadersJsApi":["brands","architecture","bitness","fullVersionList","mobile","model","platform","platformVersion"],"GEHomepageSuggestedEditsEnableTopics":true,"wgGETopicsMatchModeEnabled":false, "wgGEStructuredTaskRejectionReasonTextInputEnabled":false,"wgGELevelingUpEnabledForUser":false};RLSTATE={"ext.globalCssJs.user.styles":"ready","site.styles":"ready","user.styles":"ready","ext.globalCssJs.user":"ready","user":"ready","user.options":"loading","ext.cite.styles":"ready","mediawiki.page.gallery.styles":"ready","skins.vector.search.codex.styles":"ready","skins.vector.styles":"ready","skins.vector.icons":"ready","jquery.makeCollapsible.styles":"ready","ext.wikimediamessages.styles":"ready","ext.visualEditor.desktopArticleTarget.noscript":"ready","ext.uls.interlanguage":"ready","wikibase.client.init":"ready","ext.wikimediaBadges":"ready"};RLPAGEMODULES=["mediawiki.action.view.redirect","ext.cite.ux-enhancements","site","mediawiki.page.ready","jquery.makeCollapsible","mediawiki.toc","skins.vector.js","ext.centralNotice.geoIP","ext.centralNotice.startUp","ext.gadget.ReferenceTooltips","ext.gadget.switcher","ext.urlShortener.toolbar","ext.centralauth.centralautologin", "mmv.bootstrap","ext.popups","ext.visualEditor.desktopArticleTarget.init","ext.visualEditor.targetLoader","ext.echo.centralauth","ext.eventLogging","ext.wikimediaEvents","ext.navigationTiming","ext.uls.interface","ext.cx.eventlogging.campaigns","ext.cx.uls.quick.actions","wikibase.client.vector-2022","ext.checkUser.clientHints","ext.growthExperiments.SuggestedEditSession"];</script> <script>(RLQ=window.RLQ||[]).push(function(){mw.loader.impl(function(){return["user.options@12s5i",function($,jQuery,require,module){mw.user.tokens.set({"patrolToken":"+\\","watchToken":"+\\","csrfToken":"+\\"}); }];});});</script> <link rel="stylesheet" href="/w/load.php?lang=en&modules=ext.cite.styles%7Cext.uls.interlanguage%7Cext.visualEditor.desktopArticleTarget.noscript%7Cext.wikimediaBadges%7Cext.wikimediamessages.styles%7Cjquery.makeCollapsible.styles%7Cmediawiki.page.gallery.styles%7Cskins.vector.icons%2Cstyles%7Cskins.vector.search.codex.styles%7Cwikibase.client.init&only=styles&skin=vector-2022"> <script async="" src="/w/load.php?lang=en&modules=startup&only=scripts&raw=1&skin=vector-2022"></script> <meta name="ResourceLoaderDynamicStyles" content=""> <link rel="stylesheet" href="/w/load.php?lang=en&modules=site.styles&only=styles&skin=vector-2022"> <meta name="generator" content="MediaWiki 1.44.0-wmf.17"> <meta name="referrer" content="origin"> <meta name="referrer" content="origin-when-cross-origin"> <meta name="robots" content="max-image-preview:standard"> <meta name="format-detection" content="telephone=no"> <meta property="og:image" content="https://upload.wikimedia.org/wikipedia/commons/3/33/Protein_ITGAL_PDB_1cqp.png"> <meta property="og:image:width" content="1200"> <meta property="og:image:height" content="707"> <meta property="og:image" content="https://upload.wikimedia.org/wikipedia/commons/thumb/3/33/Protein_ITGAL_PDB_1cqp.png/800px-Protein_ITGAL_PDB_1cqp.png"> <meta property="og:image:width" content="800"> <meta property="og:image:height" content="472"> <meta property="og:image" content="https://upload.wikimedia.org/wikipedia/commons/thumb/3/33/Protein_ITGAL_PDB_1cqp.png/640px-Protein_ITGAL_PDB_1cqp.png"> <meta property="og:image:width" content="640"> <meta property="og:image:height" content="377"> <meta name="viewport" content="width=1120"> <meta property="og:title" content="Integrin alpha L - Wikipedia"> <meta property="og:type" content="website"> <link rel="preconnect" href="//upload.wikimedia.org"> <link rel="alternate" media="only screen and (max-width: 640px)" href="//en.m.wikipedia.org/wiki/Integrin_alpha_L"> <link rel="alternate" type="application/x-wiki" title="Edit this page" href="/w/index.php?title=Integrin_alpha_L&action=edit"> <link rel="apple-touch-icon" href="/static/apple-touch/wikipedia.png"> <link rel="icon" href="/static/favicon/wikipedia.ico"> <link rel="search" type="application/opensearchdescription+xml" href="/w/rest.php/v1/search" title="Wikipedia (en)"> <link rel="EditURI" type="application/rsd+xml" href="//en.wikipedia.org/w/api.php?action=rsd"> <link rel="canonical" href="https://en.wikipedia.org/wiki/Integrin_alpha_L"> <link rel="license" href="https://creativecommons.org/licenses/by-sa/4.0/deed.en"> <link rel="alternate" type="application/atom+xml" title="Wikipedia Atom feed" href="/w/index.php?title=Special:RecentChanges&feed=atom"> <link rel="dns-prefetch" href="//meta.wikimedia.org" /> <link rel="dns-prefetch" href="login.wikimedia.org"> </head> <body class="skin--responsive skin-vector skin-vector-search-vue mediawiki ltr sitedir-ltr mw-hide-empty-elt ns-0 ns-subject mw-editable page-Integrin_alpha_L rootpage-Integrin_alpha_L skin-vector-2022 action-view"><a class="mw-jump-link" href="#bodyContent">Jump to content</a> <div class="vector-header-container"> <header class="vector-header mw-header"> <div class="vector-header-start"> <nav class="vector-main-menu-landmark" aria-label="Site"> <div id="vector-main-menu-dropdown" class="vector-dropdown vector-main-menu-dropdown vector-button-flush-left vector-button-flush-right" title="Main menu" > <input type="checkbox" id="vector-main-menu-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-main-menu-dropdown" class="vector-dropdown-checkbox " aria-label="Main menu" > <label id="vector-main-menu-dropdown-label" for="vector-main-menu-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-menu mw-ui-icon-wikimedia-menu"></span> <span class="vector-dropdown-label-text">Main menu</span> </label> <div class="vector-dropdown-content"> <div id="vector-main-menu-unpinned-container" class="vector-unpinned-container"> <div id="vector-main-menu" class="vector-main-menu vector-pinnable-element"> <div class="vector-pinnable-header vector-main-menu-pinnable-header vector-pinnable-header-unpinned" data-feature-name="main-menu-pinned" data-pinnable-element-id="vector-main-menu" data-pinned-container-id="vector-main-menu-pinned-container" data-unpinned-container-id="vector-main-menu-unpinned-container" > <div class="vector-pinnable-header-label">Main menu</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-main-menu.pin">move to sidebar</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-main-menu.unpin">hide</button> </div> <div id="p-navigation" class="vector-menu mw-portlet mw-portlet-navigation" > <div class="vector-menu-heading"> Navigation </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="n-mainpage-description" class="mw-list-item"><a href="/wiki/Main_Page" title="Visit the main page [z]" accesskey="z"><span>Main page</span></a></li><li id="n-contents" class="mw-list-item"><a href="/wiki/Wikipedia:Contents" title="Guides to browsing Wikipedia"><span>Contents</span></a></li><li id="n-currentevents" class="mw-list-item"><a href="/wiki/Portal:Current_events" title="Articles related to current events"><span>Current events</span></a></li><li id="n-randompage" class="mw-list-item"><a href="/wiki/Special:Random" title="Visit a randomly selected article [x]" accesskey="x"><span>Random article</span></a></li><li id="n-aboutsite" class="mw-list-item"><a href="/wiki/Wikipedia:About" title="Learn about Wikipedia and how it works"><span>About Wikipedia</span></a></li><li id="n-contactpage" class="mw-list-item"><a href="//en.wikipedia.org/wiki/Wikipedia:Contact_us" title="How to contact Wikipedia"><span>Contact us</span></a></li> </ul> </div> </div> <div id="p-interaction" class="vector-menu mw-portlet mw-portlet-interaction" > <div class="vector-menu-heading"> Contribute </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="n-help" class="mw-list-item"><a href="/wiki/Help:Contents" title="Guidance on how to use and edit Wikipedia"><span>Help</span></a></li><li id="n-introduction" class="mw-list-item"><a href="/wiki/Help:Introduction" title="Learn how to edit Wikipedia"><span>Learn to edit</span></a></li><li id="n-portal" class="mw-list-item"><a href="/wiki/Wikipedia:Community_portal" title="The hub for editors"><span>Community portal</span></a></li><li id="n-recentchanges" class="mw-list-item"><a href="/wiki/Special:RecentChanges" title="A list of recent changes to Wikipedia [r]" accesskey="r"><span>Recent changes</span></a></li><li id="n-upload" class="mw-list-item"><a href="/wiki/Wikipedia:File_upload_wizard" title="Add images or other media for use on Wikipedia"><span>Upload file</span></a></li><li id="n-specialpages" class="mw-list-item"><a href="/wiki/Special:SpecialPages"><span>Special pages</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> <a href="/wiki/Main_Page" class="mw-logo"> <img class="mw-logo-icon" src="/static/images/icons/wikipedia.png" alt="" aria-hidden="true" height="50" width="50"> <span class="mw-logo-container skin-invert"> <img class="mw-logo-wordmark" alt="Wikipedia" src="/static/images/mobile/copyright/wikipedia-wordmark-en.svg" style="width: 7.5em; height: 1.125em;"> <img class="mw-logo-tagline" alt="The Free Encyclopedia" src="/static/images/mobile/copyright/wikipedia-tagline-en.svg" width="117" height="13" style="width: 7.3125em; height: 0.8125em;"> </span> </a> </div> <div class="vector-header-end"> <div id="p-search" role="search" class="vector-search-box-vue vector-search-box-collapses vector-search-box-show-thumbnail vector-search-box-auto-expand-width vector-search-box"> <a href="/wiki/Special:Search" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only search-toggle" title="Search Wikipedia [f]" accesskey="f"><span class="vector-icon mw-ui-icon-search mw-ui-icon-wikimedia-search"></span> <span>Search</span> </a> <div class="vector-typeahead-search-container"> <div class="cdx-typeahead-search cdx-typeahead-search--show-thumbnail cdx-typeahead-search--auto-expand-width"> <form action="/w/index.php" id="searchform" class="cdx-search-input cdx-search-input--has-end-button"> <div id="simpleSearch" class="cdx-search-input__input-wrapper" data-search-loc="header-moved"> <div class="cdx-text-input cdx-text-input--has-start-icon"> <input class="cdx-text-input__input" type="search" name="search" placeholder="Search Wikipedia" aria-label="Search Wikipedia" autocapitalize="sentences" title="Search Wikipedia [f]" accesskey="f" id="searchInput" > <span class="cdx-text-input__icon cdx-text-input__start-icon"></span> </div> <input type="hidden" name="title" value="Special:Search"> </div> <button class="cdx-button cdx-search-input__end-button">Search</button> </form> </div> </div> </div> <nav class="vector-user-links vector-user-links-wide" aria-label="Personal tools"> <div class="vector-user-links-main"> <div id="p-vector-user-menu-preferences" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <div id="p-vector-user-menu-userpage" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <nav class="vector-appearance-landmark" aria-label="Appearance"> <div id="vector-appearance-dropdown" class="vector-dropdown " title="Change the appearance of the page's font size, width, and color" > <input type="checkbox" id="vector-appearance-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-appearance-dropdown" class="vector-dropdown-checkbox " aria-label="Appearance" > <label id="vector-appearance-dropdown-label" for="vector-appearance-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-appearance mw-ui-icon-wikimedia-appearance"></span> <span class="vector-dropdown-label-text">Appearance</span> </label> <div class="vector-dropdown-content"> <div id="vector-appearance-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <div id="p-vector-user-menu-notifications" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <div id="p-vector-user-menu-overflow" class="vector-menu mw-portlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-sitesupport-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="https://donate.wikimedia.org/?wmf_source=donate&wmf_medium=sidebar&wmf_campaign=en.wikipedia.org&uselang=en" class=""><span>Donate</span></a> </li> <li id="pt-createaccount-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=Special:CreateAccount&returnto=Integrin+alpha+L" title="You are encouraged to create an account and log in; however, it is not mandatory" class=""><span>Create account</span></a> </li> <li id="pt-login-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=Special:UserLogin&returnto=Integrin+alpha+L" title="You're encouraged to log in; however, it's not mandatory. [o]" accesskey="o" class=""><span>Log in</span></a> </li> </ul> </div> </div> </div> <div id="vector-user-links-dropdown" class="vector-dropdown vector-user-menu vector-button-flush-right vector-user-menu-logged-out" title="Log in and more options" > <input type="checkbox" id="vector-user-links-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-user-links-dropdown" class="vector-dropdown-checkbox " aria-label="Personal tools" > <label id="vector-user-links-dropdown-label" for="vector-user-links-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-ellipsis mw-ui-icon-wikimedia-ellipsis"></span> <span class="vector-dropdown-label-text">Personal tools</span> </label> <div class="vector-dropdown-content"> <div id="p-personal" class="vector-menu mw-portlet mw-portlet-personal user-links-collapsible-item" title="User menu" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-sitesupport" class="user-links-collapsible-item mw-list-item"><a href="https://donate.wikimedia.org/?wmf_source=donate&wmf_medium=sidebar&wmf_campaign=en.wikipedia.org&uselang=en"><span>Donate</span></a></li><li id="pt-createaccount" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=Special:CreateAccount&returnto=Integrin+alpha+L" title="You are encouraged to create an account and log in; however, it is not mandatory"><span class="vector-icon mw-ui-icon-userAdd mw-ui-icon-wikimedia-userAdd"></span> <span>Create account</span></a></li><li id="pt-login" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=Special:UserLogin&returnto=Integrin+alpha+L" title="You're encouraged to log in; however, it's not mandatory. [o]" accesskey="o"><span class="vector-icon mw-ui-icon-logIn mw-ui-icon-wikimedia-logIn"></span> <span>Log in</span></a></li> </ul> </div> </div> <div id="p-user-menu-anon-editor" class="vector-menu mw-portlet mw-portlet-user-menu-anon-editor" > <div class="vector-menu-heading"> Pages for logged out editors <a href="/wiki/Help:Introduction" aria-label="Learn more about editing"><span>learn more</span></a> </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-anoncontribs" class="mw-list-item"><a href="/wiki/Special:MyContributions" title="A list of edits made from this IP address [y]" accesskey="y"><span>Contributions</span></a></li><li id="pt-anontalk" class="mw-list-item"><a href="/wiki/Special:MyTalk" title="Discussion about edits from this IP address [n]" accesskey="n"><span>Talk</span></a></li> </ul> </div> </div> </div> </div> </nav> </div> </header> </div> <div class="mw-page-container"> <div class="mw-page-container-inner"> <div class="vector-sitenotice-container"> <div id="siteNotice"></div> </div> <div class="vector-column-start"> <div class="vector-main-menu-container"> <div id="mw-navigation"> <nav id="mw-panel" class="vector-main-menu-landmark" aria-label="Site"> <div id="vector-main-menu-pinned-container" class="vector-pinned-container"> </div> </nav> </div> </div> <div class="vector-sticky-pinned-container"> <nav id="mw-panel-toc" aria-label="Contents" data-event-name="ui.sidebar-toc" class="mw-table-of-contents-container vector-toc-landmark"> <div id="vector-toc-pinned-container" class="vector-pinned-container"> <div id="vector-toc" class="vector-toc vector-pinnable-element"> <div class="vector-pinnable-header vector-toc-pinnable-header vector-pinnable-header-pinned" data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">Contents</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">move to sidebar</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">hide</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">(Top)</div> </a> </li> <li id="toc-Function" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Function"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Function</span> </div> </a> <ul id="toc-Function-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Interactions" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Interactions"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Interactions</span> </div> </a> <ul id="toc-Interactions-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-See_also" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#See_also"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>See also</span> </div> </a> <ul id="toc-See_also-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-References" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#References"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>References</span> </div> </a> <ul id="toc-References-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Further_reading" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Further_reading"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>Further reading</span> </div> </a> <ul id="toc-Further_reading-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-External_links" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#External_links"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>External links</span> </div> </a> <ul id="toc-External_links-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Contents" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" title="Table of Contents" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Toggle the table of contents" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Toggle the table of contents</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Integrin alpha L</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Go to an article in another language. Available in 9 languages" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-9" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">9 languages</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-cy mw-list-item"><a href="https://cy.wikipedia.org/wiki/ITGAL" title="ITGAL – Welsh" lang="cy" hreflang="cy" data-title="ITGAL" data-language-autonym="Cymraeg" data-language-local-name="Welsh" class="interlanguage-link-target"><span>Cymraeg</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Integrin_%CE%B1-L" title="Integrin α-L – German" lang="de" hreflang="de" data-title="Integrin α-L" data-language-autonym="Deutsch" data-language-local-name="German" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/CD11" title="CD11 – Spanish" lang="es" hreflang="es" data-title="CD11" data-language-autonym="Español" data-language-local-name="Spanish" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/CD11a" title="CD11a – Persian" lang="fa" hreflang="fa" data-title="CD11a" data-language-autonym="فارسی" data-language-local-name="Persian" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/CD11a" title="CD11a – Galician" lang="gl" hreflang="gl" data-title="CD11a" data-language-autonym="Galego" data-language-local-name="Galician" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/CD11a" title="CD11a – Italian" lang="it" hreflang="it" data-title="CD11a" data-language-autonym="Italiano" data-language-local-name="Italian" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%98%D0%BD%D1%82%D0%B5%D0%B3%D1%80%D0%B8%D0%BD_%D0%B0%D0%BB%D1%8C%D1%84%D0%B0-L" title="Интегрин альфа-L – Russian" lang="ru" hreflang="ru" data-title="Интегрин альфа-L" data-language-autonym="Русский" data-language-local-name="Russian" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-tt mw-list-item"><a href="https://tt.wikipedia.org/wiki/ITGAL" title="ITGAL – Tatar" lang="tt" hreflang="tt" data-title="ITGAL" data-language-autonym="Татарча / tatarça" data-language-local-name="Tatar" class="interlanguage-link-target"><span>Татарча / tatarça</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/ITGAL" title="ITGAL – Ukrainian" lang="uk" hreflang="uk" data-title="ITGAL" data-language-autonym="Українська" data-language-local-name="Ukrainian" class="interlanguage-link-target"><span>Українська</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q3648604#sitelinks-wikipedia" title="Edit interlanguage links" class="wbc-editpage">Edit links</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Namespaces"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/Integrin_alpha_L" title="View the content page [c]" accesskey="c"><span>Article</span></a></li><li id="ca-talk" class="vector-tab-noicon mw-list-item"><a href="/wiki/Talk:Integrin_alpha_L" rel="discussion" title="Discuss improvements to the content page [t]" accesskey="t"><span>Talk</span></a></li> </ul> </div> </div> <div id="vector-variants-dropdown" class="vector-dropdown emptyPortlet" > <input type="checkbox" id="vector-variants-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-variants-dropdown" class="vector-dropdown-checkbox " aria-label="Change language variant" > <label id="vector-variants-dropdown-label" for="vector-variants-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">English</span> </label> <div class="vector-dropdown-content"> <div id="p-variants" class="vector-menu mw-portlet mw-portlet-variants emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> </div> </div> </nav> </div> <div id="right-navigation" class="vector-collapsible"> <nav aria-label="Views"> <div id="p-views" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-views" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-view" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/Integrin_alpha_L"><span>Read</span></a></li><li id="ca-edit" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Integrin_alpha_L&action=edit" title="Edit this page [e]" accesskey="e"><span>Edit</span></a></li><li id="ca-history" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Integrin_alpha_L&action=history" title="Past revisions of this page [h]" accesskey="h"><span>View history</span></a></li> </ul> </div> </div> </nav> <nav class="vector-page-tools-landmark" aria-label="Page tools"> <div id="vector-page-tools-dropdown" class="vector-dropdown vector-page-tools-dropdown" > <input type="checkbox" id="vector-page-tools-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-tools-dropdown" class="vector-dropdown-checkbox " aria-label="Tools" > <label id="vector-page-tools-dropdown-label" for="vector-page-tools-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">Tools</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-tools-unpinned-container" class="vector-unpinned-container"> <div id="vector-page-tools" class="vector-page-tools vector-pinnable-element"> <div class="vector-pinnable-header vector-page-tools-pinnable-header vector-pinnable-header-unpinned" data-feature-name="page-tools-pinned" data-pinnable-element-id="vector-page-tools" data-pinned-container-id="vector-page-tools-pinned-container" data-unpinned-container-id="vector-page-tools-unpinned-container" > <div class="vector-pinnable-header-label">Tools</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-page-tools.pin">move to sidebar</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-page-tools.unpin">hide</button> </div> <div id="p-cactions" class="vector-menu mw-portlet mw-portlet-cactions emptyPortlet vector-has-collapsible-items" title="More options" > <div class="vector-menu-heading"> Actions </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-more-view" class="selected vector-more-collapsible-item mw-list-item"><a href="/wiki/Integrin_alpha_L"><span>Read</span></a></li><li id="ca-more-edit" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Integrin_alpha_L&action=edit" title="Edit this page [e]" accesskey="e"><span>Edit</span></a></li><li id="ca-more-history" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Integrin_alpha_L&action=history"><span>View history</span></a></li> </ul> </div> </div> <div id="p-tb" class="vector-menu mw-portlet mw-portlet-tb" > <div class="vector-menu-heading"> General </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-whatlinkshere" class="mw-list-item"><a href="/wiki/Special:WhatLinksHere/Integrin_alpha_L" title="List of all English Wikipedia pages containing links to this page [j]" accesskey="j"><span>What links here</span></a></li><li id="t-recentchangeslinked" class="mw-list-item"><a href="/wiki/Special:RecentChangesLinked/Integrin_alpha_L" rel="nofollow" title="Recent changes in pages linked from this page [k]" accesskey="k"><span>Related changes</span></a></li><li id="t-upload" class="mw-list-item"><a href="//en.wikipedia.org/wiki/Wikipedia:File_Upload_Wizard" title="Upload files [u]" accesskey="u"><span>Upload file</span></a></li><li id="t-permalink" class="mw-list-item"><a href="/w/index.php?title=Integrin_alpha_L&oldid=1228262317" title="Permanent link to this revision of this page"><span>Permanent link</span></a></li><li id="t-info" class="mw-list-item"><a href="/w/index.php?title=Integrin_alpha_L&action=info" title="More information about this page"><span>Page information</span></a></li><li id="t-cite" class="mw-list-item"><a href="/w/index.php?title=Special:CiteThisPage&page=Integrin_alpha_L&id=1228262317&wpFormIdentifier=titleform" title="Information on how to cite this page"><span>Cite this page</span></a></li><li id="t-urlshortener" class="mw-list-item"><a href="/w/index.php?title=Special:UrlShortener&url=https%3A%2F%2Fen.wikipedia.org%2Fwiki%2FIntegrin_alpha_L"><span>Get shortened URL</span></a></li><li id="t-urlshortener-qrcode" class="mw-list-item"><a href="/w/index.php?title=Special:QrCode&url=https%3A%2F%2Fen.wikipedia.org%2Fwiki%2FIntegrin_alpha_L"><span>Download QR code</span></a></li> </ul> </div> </div> <div id="p-coll-print_export" class="vector-menu mw-portlet mw-portlet-coll-print_export" > <div class="vector-menu-heading"> Print/export </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="coll-download-as-rl" class="mw-list-item"><a href="/w/index.php?title=Special:DownloadAsPdf&page=Integrin_alpha_L&action=show-download-screen" title="Download this page as a PDF file"><span>Download as PDF</span></a></li><li id="t-print" class="mw-list-item"><a href="/w/index.php?title=Integrin_alpha_L&printable=yes" title="Printable version of this page [p]" accesskey="p"><span>Printable version</span></a></li> </ul> </div> </div> <div id="p-wikibase-otherprojects" class="vector-menu mw-portlet mw-portlet-wikibase-otherprojects" > <div class="vector-menu-heading"> In other projects </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-wikibase" class="wb-otherproject-link wb-otherproject-wikibase-dataitem mw-list-item"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q3648604" title="Structured data on this page hosted by Wikidata [g]" accesskey="g"><span>Wikidata item</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> </div> </div> </div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="Page tools"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="Appearance"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Appearance</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">move to sidebar</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">hide</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">From Wikipedia, the free encyclopedia</div> </div> <div id="contentSub"><div id="mw-content-subtitle"><span class="mw-redirectedfrom">(Redirected from <a href="/w/index.php?title=CD11a&redirect=no" class="mw-redirect" title="CD11a">CD11a</a>)</span></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="en" dir="ltr"><p class="mw-empty-elt"> </p> <div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">Mammalian protein found in Homo sapiens</div> <table class="infobox" style="width:26.4em"><tbody><tr><th colspan="4" style="text-align:center;font-size:125%;font-weight:bold">ITGAL</th></tr><tr><td colspan="4" style="text-align:center"><span typeof="mw:File"><a href="/wiki/File:Protein_ITGAL_PDB_1cqp.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/3/33/Protein_ITGAL_PDB_1cqp.png/250px-Protein_ITGAL_PDB_1cqp.png" decoding="async" width="250" height="147" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/33/Protein_ITGAL_PDB_1cqp.png/375px-Protein_ITGAL_PDB_1cqp.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/33/Protein_ITGAL_PDB_1cqp.png/500px-Protein_ITGAL_PDB_1cqp.png 2x" data-file-width="1016" data-file-height="599" /></a></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><table style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:light-dark(#ddd, #404244) !important;color:inherit">Available structures</th></tr><tr><th rowspan="2" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit;width:43px"><a href="/wiki/Protein_Data_Bank" title="Protein Data Bank">PDB</a></th><td colspan="2" style="background-color:light-dark(#eee, #27292d) !important;color:inherit">Ortholog search: <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/pdbe/searchResults.html?display=both&term=P24063%20or%20P20701%20or%20H3BSV1">PDBe</a> <a rel="nofollow" class="external text" href="https://www.rcsb.org/search?q=rcsb_polymer_entity_container_identifiers.reference_sequence_identifiers.database_name:UniProt%20AND%20rcsb_polymer_entity_container_identifiers.reference_sequence_identifiers.database_accession:P24063,P20701,H3BSV1">RCSB</a> </span></td></tr><tr><td><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr style="text-align:center"><th colspan="2" style="background-color:light-dark(#ddd, #404244) !important;color:inherit">List of PDB id codes</th></tr><tr><td colspan="2" style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/4IXD">4IXD</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1CQP">1CQP</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1DGQ">1DGQ</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1LFA">1LFA</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1MJN">1MJN</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1MQ8">1MQ8</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1MQ9">1MQ9</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1MQA">1MQA</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1RD4">1RD4</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1T0P">1T0P</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1XDD">1XDD</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1XDG">1XDG</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1XUO">1XUO</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1ZON">1ZON</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1ZOO">1ZOO</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1ZOP">1ZOP</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2ICA">2ICA</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2K8O">2K8O</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2M3E">2M3E</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2O7N">2O7N</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3BN3">3BN3</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3BQM">3BQM</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3BQN">3BQN</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3E2M">3E2M</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3EOA">3EOA</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3EOB">3EOB</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3F74">3F74</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3F78">3F78</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3HI6">3HI6</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3M6F">3M6F</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3TCX">3TCX</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/5E6S">5E6S</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/5E6R">5E6R</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/5E6U">5E6U</a></span></p></td></tr></tbody></table></td></tr></tbody></table></td></tr><tr><th colspan="4" style="text-align:center;background-color:light-dark(#ddd, #404244) !important;color:inherit">Identifiers</th></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><span class="plainlinks"><a href="/wiki/Gene_nomenclature" title="Gene nomenclature">Aliases</a></span></th><td colspan="3" style="background:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/6148">ITGAL</a></span>, CD11A, LFA-1, LFA1A, integrin subunit alpha L</td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit">External IDs</th><td colspan="3" style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks"><a href="/wiki/Mendelian_Inheritance_in_Man" class="mw-redirect" title="Mendelian Inheritance in Man">OMIM</a>: <a rel="nofollow" class="external text" href="https://omim.org/entry/153370">153370</a>; <a href="/wiki/Mouse_Genome_Informatics" title="Mouse Genome Informatics">MGI</a>: <a rel="nofollow" class="external text" href="http://www.informatics.jax.org/marker/MGI:96606">96606</a>; <a href="/wiki/HomoloGene" title="HomoloGene">HomoloGene</a>: <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=homologene&dopt=HomoloGene&list_uids=1666">1666</a>; <a href="/wiki/GeneCards" title="GeneCards">GeneCards</a>: <a rel="nofollow" class="external text" href="https://www.genecards.org/cgi-bin/carddisp.pl?gene=ITGAL">ITGAL</a>; <a href="/wiki/Orthologous_MAtrix" title="Orthologous MAtrix">OMA</a>:<a rel="nofollow" class="external text" href="https://omabrowser.org/oma/vps/ENSG00000005844">ITGAL - orthologs</a></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:light-dark(#ddd, #404244) !important;color:inherit">Gene location (<a href="/wiki/Human_genome" title="Human genome">Human</a>)</th></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><span typeof="mw:File"><a href="/wiki/File:Ideogram_human_chromosome_16.svg" class="mw-file-description" title="Chromosome 16 (human)"><img alt="Chromosome 16 (human)" src="//upload.wikimedia.org/wikipedia/commons/thumb/2/2d/Ideogram_human_chromosome_16.svg/300px-Ideogram_human_chromosome_16.svg.png" decoding="async" width="300" height="120" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/2d/Ideogram_human_chromosome_16.svg/450px-Ideogram_human_chromosome_16.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/2d/Ideogram_human_chromosome_16.svg/600px-Ideogram_human_chromosome_16.svg.png 2x" data-file-width="474" data-file-height="189" /></a></span></td></tr><tr><th scope="row" width="15%" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a href="/wiki/Chromosome" title="Chromosome">Chr.</a></th><td colspan="3" width="85%" style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks"><a href="/wiki/Chromosome_16_(human)" class="mw-redirect" title="Chromosome 16 (human)">Chromosome 16 (human)</a><sup id="cite_ref-refGRCh38Ensembl_1-0" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><div align="center"><div style="position: relative; width: 300px;"><span typeof="mw:File"><a href="/wiki/File:Human_chromosome_16_ideogram.svg" class="mw-file-description" title="Chromosome 16 (human)"><img alt="Chromosome 16 (human)" src="//upload.wikimedia.org/wikipedia/commons/thumb/c/c3/Human_chromosome_16_ideogram.svg/300px-Human_chromosome_16_ideogram.svg.png" decoding="async" width="300" height="58" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/c/c3/Human_chromosome_16_ideogram.svg/450px-Human_chromosome_16_ideogram.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/c/c3/Human_chromosome_16_ideogram.svg/600px-Human_chromosome_16_ideogram.svg.png 2x" data-file-width="1125" data-file-height="216" /></a></span><div style="position: absolute; left: 93.899001144918px; top: 2px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:HSR_1996_II_3.5e.svg" class="mw-file-description" title="Genomic location for ITGAL"><img alt="Genomic location for ITGAL" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/14px-HSR_1996_II_3.5e.svg.png" decoding="async" width="14" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/21px-HSR_1996_II_3.5e.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/28px-HSR_1996_II_3.5e.svg.png 2x" data-file-width="142" data-file-height="142" /></a></span></div><div style="position: absolute; left: 99.9px; top: 19px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:Red_rectangle_2x18.png" class="mw-file-description" title="Genomic location for ITGAL"><img alt="Genomic location for ITGAL" src="//upload.wikimedia.org/wikipedia/commons/6/6a/Red_rectangle_2x18.png" decoding="async" width="2" height="18" class="mw-file-element" data-file-width="2" data-file-height="18" /></a></span></div></div></div></td></tr><tr><th scope="row" rowspan="2" width="15%" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a href="/wiki/Locus_(genetics)" title="Locus (genetics)">Band</a></th><td rowspan="2" width="35%" style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks">16p11.2</span></td><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit">Start</th><td style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks">30,472,658 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCh38Ensembl_1-1" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit">End</th><td style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks">30,523,567 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCh38Ensembl_1-2" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:light-dark(#ddd, #404244) !important;color:inherit">Gene location (<a href="/wiki/Laboratory_mouse" title="Laboratory mouse">Mouse</a>)</th></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><span typeof="mw:File"><a href="/wiki/File:Ideogram_house_mouse_chromosome_7.svg" class="mw-file-description" title="Chromosome 7 (mouse)"><img alt="Chromosome 7 (mouse)" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e4/Ideogram_house_mouse_chromosome_7.svg/260px-Ideogram_house_mouse_chromosome_7.svg.png" decoding="async" width="260" height="111" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e4/Ideogram_house_mouse_chromosome_7.svg/390px-Ideogram_house_mouse_chromosome_7.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e4/Ideogram_house_mouse_chromosome_7.svg/520px-Ideogram_house_mouse_chromosome_7.svg.png 2x" data-file-width="470" data-file-height="200" /></a></span></td></tr><tr><th scope="row" width="15%" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a href="/wiki/Chromosome" title="Chromosome">Chr.</a></th><td colspan="3" width="85%" style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks">Chromosome 7 (mouse)<sup id="cite_ref-refGRCm38Ensembl_2-0" class="reference"><a href="#cite_note-refGRCm38Ensembl-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><div align="center"><div style="position: relative; width: 300px;"><span typeof="mw:File"><a href="/wiki/File:Ideogram_of_house_mouse_chromosome_7.svg" class="mw-file-description" title="Chromosome 7 (mouse)"><img alt="Chromosome 7 (mouse)" src="//upload.wikimedia.org/wikipedia/commons/thumb/2/2c/Ideogram_of_house_mouse_chromosome_7.svg/300px-Ideogram_of_house_mouse_chromosome_7.svg.png" decoding="async" width="300" height="58" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/2c/Ideogram_of_house_mouse_chromosome_7.svg/450px-Ideogram_of_house_mouse_chromosome_7.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/2c/Ideogram_of_house_mouse_chromosome_7.svg/600px-Ideogram_of_house_mouse_chromosome_7.svg.png 2x" data-file-width="1200" data-file-height="231" /></a></span><div style="position: absolute; left: 251.26599738124px; top: 2px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:HSR_1996_II_3.5e.svg" class="mw-file-description" title="Genomic location for ITGAL"><img alt="Genomic location for ITGAL" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/14px-HSR_1996_II_3.5e.svg.png" decoding="async" width="14" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/21px-HSR_1996_II_3.5e.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/28px-HSR_1996_II_3.5e.svg.png 2x" data-file-width="142" data-file-height="142" /></a></span></div><div style="position: absolute; left: 257.3px; top: 19px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:Red_rectangle_2x18.png" class="mw-file-description" title="Genomic location for ITGAL"><img alt="Genomic location for ITGAL" src="//upload.wikimedia.org/wikipedia/commons/6/6a/Red_rectangle_2x18.png" decoding="async" width="2" height="18" class="mw-file-element" data-file-width="2" data-file-height="18" /></a></span></div></div></div></td></tr><tr><th scope="row" rowspan="2" width="15%" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a href="/wiki/Locus_(genetics)" title="Locus (genetics)">Band</a></th><td rowspan="2" width="35%" style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks">7 F3|7 69.44 cM</span></td><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit">Start</th><td style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks">126,895,432 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCm38Ensembl_2-1" class="reference"><a href="#cite_note-refGRCm38Ensembl-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit">End</th><td style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks">126,934,310 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCm38Ensembl_2-2" class="reference"><a href="#cite_note-refGRCm38Ensembl-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:light-dark(#ddd, #404244) !important;color:inherit"><a href="/wiki/Gene_expression" title="Gene expression">RNA expression</a> pattern</th></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a rel="nofollow" class="external text" href="https://www.bgee.org/">Bgee</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th><b><a href="/wiki/Human_genome" title="Human genome">Human</a></b></th><th><b><a href="/wiki/Laboratory_mouse" title="Laboratory mouse">Mouse</a> (ortholog)</b></th></tr><tr><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="1"><span class="plainlinks" style="margin:-3px"><a rel="nofollow" class="external text" href="https://www.bgee.org/gene/ENSG00000005844">Top expressed in</a></span></td></tr><tr><td colspan="1"><div class="plainlinks" style="margin:-12px 0px -10px 0px"><ul style="line-height:15%;margin:9px"><li style="line-height: 137%;">granulocyte</li><br /><li style="line-height: 137%;">monocyte</li><br /><li style="line-height: 137%;">blood</li><br /><li style="line-height: 137%;">spleen</li><br /><li style="line-height: 137%;">lymph node</li><br /><li style="line-height: 137%;">bone marrow cells</li><br /><li style="line-height: 137%;">appendix</li><br /><li style="line-height: 137%;">thymus</li><br /><li style="line-height: 137%;">upper lobe of left lung</li><br /><li style="line-height: 137%;">epithelium of colon</li></ul></div></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="1"><span class="plainlinks" style="margin:-3px"><a rel="nofollow" class="external text" href="https://www.bgee.org/gene/ENSMUSG00000030830">Top expressed in</a></span></td></tr><tr><td colspan="1"><div class="plainlinks" style="margin:-12px 0px -10px 0px"><ul style="line-height:15%;margin:9px"><li style="line-height: 137%;">granulocyte</li><br /><li style="line-height: 137%;">thymus</li><br /><li style="line-height: 137%;">mesenteric lymph nodes</li><br /><li style="line-height: 137%;">blood</li><br /><li style="line-height: 137%;">spleen</li><br /><li style="line-height: 137%;">subcutaneous adipose tissue</li><br /><li style="line-height: 137%;">submandibular gland</li><br /><li style="line-height: 137%;">bone marrow</li><br /><li style="line-height: 137%;">right lung lobe</li><br /><li style="line-height: 137%;">stroma of bone marrow</li></ul></div></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.bgee.org/gene/ENSG00000005844">More reference expression data</a></span></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a rel="nofollow" class="external text" href="http://biogps.org/">BioGPS</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><span typeof="mw:File"><a href="/wiki/File:PBB_GE_ITGAL_213475_s_at_fs.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/PBB_GE_ITGAL_213475_s_at_fs.png/250px-PBB_GE_ITGAL_213475_s_at_fs.png" decoding="async" width="250" height="181" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/PBB_GE_ITGAL_213475_s_at_fs.png/375px-PBB_GE_ITGAL_213475_s_at_fs.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/b1/PBB_GE_ITGAL_213475_s_at_fs.png/500px-PBB_GE_ITGAL_213475_s_at_fs.png 2x" data-file-width="732" data-file-height="530" /></a></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks"><a rel="nofollow" class="external text" href="http://biogps.org/gene/3683/">More reference expression data</a></span></td></tr></tbody></table></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:light-dark(#ddd, #404244) !important;color:inherit"><a href="/wiki/Gene_ontology" class="mw-redirect" title="Gene ontology">Gene ontology</a></th></tr><tr><td style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit;font-weight:bold">Molecular function</td><td style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><div class="plainlinks"> <ul><li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0044877">protein-containing complex binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0046872">metal ion binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005515">protein binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0046982">protein heterodimerization activity</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0030369">ICAM-3 receptor activity</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0050839">cell adhesion molecule binding</a></li></ul> </div></td></tr><tr><td style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit;font-weight:bold">Cellular component</td><td style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><div class="plainlinks"> <ul><li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0016021">integral component of membrane</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0034687">integrin alphaL-beta2 complex</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0016020">membrane</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0009986">cell surface</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0008305">integrin complex</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0070062">extracellular exosome</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005886">plasma membrane</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0035579">specific granule membrane</a></li></ul> </div></td></tr><tr><td style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit;font-weight:bold">Biological process</td><td style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><div class="plainlinks"> <ul><li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0007159">leukocyte cell-cell adhesion</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0007157">heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0002291">T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0030198">extracellular matrix organization</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0043113">receptor clustering</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0007155">cell adhesion</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0050776">regulation of immune response</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0007229">integrin-mediated signaling pathway</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0007160">cell-matrix adhesion</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0006954">inflammatory response</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0050900">leukocyte migration</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0007165">signal transduction</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0006909">phagocytosis</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0043312">neutrophil degranulation</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0098609">cell-cell adhesion</a></li></ul> </div></td></tr><tr><td colspan="4" style="background-color:light-dark(#eee, #27292d) !important;color:inherit;text-align:center">Sources:<a rel="nofollow" class="external text" href="http://amigo.geneontology.org/">Amigo</a> / <a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/QuickGO/">QuickGO</a></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><table class="collapsible" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:light-dark(#ddd, #404244) !important;color:inherit"><a href="/wiki/Orthologs" class="mw-redirect" title="Orthologs">Orthologs</a></th></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit">Species</th><td><b>Human</b></td><td><b>Mouse</b></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a href="/wiki/Entrez" title="Entrez">Entrez</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=3683&rn=1">3683</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=16408&rn=1">16408</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a href="/wiki/Ensembl" class="mw-redirect" title="Ensembl">Ensembl</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Homo_sapiens/geneview?gene=ENSG00000005844;db=core">ENSG00000005844</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Mus_musculus/geneview?gene=ENSMUSG00000030830;db=core">ENSMUSG00000030830</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a href="/wiki/UniProt" title="UniProt">UniProt</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/P20701">P20701</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/P24063">P24063</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit">RefSeq (mRNA)</th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001114380">NM_001114380</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_002209">NM_002209</a></span></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001253872">NM_001253872</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001253873">NM_001253873</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001253874">NM_001253874</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_008400">NM_008400</a></span></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit">RefSeq (protein)</th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001107852">NP_001107852</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_002200">NP_002200</a></span></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001240801">NP_001240801</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001240802">NP_001240802</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001240803">NP_001240803</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_032426">NP_032426</a></span></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit">Location (UCSC)</th><td><span class="plainlinks"><a rel="nofollow" class="external text" href="https://genome.ucsc.edu/cgi-bin/hgTracks?org=Human&db=hg38&position=chr16:30472658-30523567">Chr 16: 30.47 – 30.52 Mb</a></span></td><td><span class="plainlinks"><a rel="nofollow" class="external text" href="https://genome.ucsc.edu/cgi-bin/hgTracks?org=Mouse&db=mm0&position=chr7:126895432-126934310">Chr 7: 126.9 – 126.93 Mb</a></span></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a href="/wiki/PubMed" title="PubMed">PubMed</a> search</th><td><span class="plainlinks"><sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup></span></td><td><span class="plainlinks"><sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><a href="/wiki/Wikidata" title="Wikidata">Wikidata</a></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><table style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="2" style="background-color:light-dark(#eee, #27292d) !important;color:inherit;text-align:center"><a href="https://www.wikidata.org/wiki/Q14904995" class="extiw" title="d:Q14904995">View/Edit Human</a></td><td colspan="2" style="background-color:light-dark(#eee, #27292d) !important;color:inherit;text-align:center"><a href="https://www.wikidata.org/wiki/Q14904996" class="extiw" title="d:Q14904996">View/Edit Mouse</a></td></tr></tbody></table></td></tr></tbody></table> <p><b>Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)</b>, also known as <b>ITGAL</b>, is a protein that in humans is encoded by the <i>ITGAL</i> <a href="/wiki/Gene" title="Gene">gene</a>.<sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> CD11a functions in the immune system. It is involved in cellular adhesion and costimulatory signaling. It is the target of the drug <a href="/wiki/Efalizumab" title="Efalizumab">efalizumab</a>. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Function">Function</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Integrin_alpha_L&action=edit&section=1" title="Edit section: Function"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><i>ITGAL</i> gene encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed in all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling.<sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p><p>CD11a is one of the two components, along with <a href="/wiki/CD18" class="mw-redirect" title="CD18">CD18</a>, which form <a href="/wiki/Lymphocyte_function-associated_antigen-1" class="mw-redirect" title="Lymphocyte function-associated antigen-1">lymphocyte function-associated antigen-1</a>. </p><p><a href="/wiki/Efalizumab" title="Efalizumab">Efalizumab</a> acts as an <a href="/wiki/Immunosuppressant" class="mw-redirect" title="Immunosuppressant">immunosuppressant</a> by binding to CD11a but was withdrawn in 2009 because it was associated with severe side effects. </p> <div class="mw-heading mw-heading2"><h2 id="Interactions">Interactions</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Integrin_alpha_L&action=edit&section=2" title="Edit section: Interactions"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>CD11a has been shown to <a href="/wiki/Protein-protein_interaction" class="mw-redirect" title="Protein-protein interaction">interact</a> with <a href="/wiki/ICAM-1" title="ICAM-1">ICAM-1</a>.<sup id="cite_ref-pmid11279101_7-0" class="reference"><a href="#cite_note-pmid11279101-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid12526797_8-0" class="reference"><a href="#cite_note-pmid12526797-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid11786177_9-0" class="reference"><a href="#cite_note-pmid11786177-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="See_also">See also</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Integrin_alpha_L&action=edit&section=3" title="Edit section: See also"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/CD11c" class="mw-redirect" title="CD11c">CD11c</a></li> <li><a href="/wiki/Integrin" title="Integrin">integrin</a></li> <li><a href="/wiki/Leukocyte_adhesion_deficiency" title="Leukocyte adhesion deficiency">leukocyte adhesion deficiency</a></li> <li><a href="/wiki/Cluster_of_differentiation" title="Cluster of differentiation">Cluster of differentiation</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Integrin_alpha_L&action=edit&section=4" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-refGRCh38Ensembl-1"><span class="mw-cite-backlink">^ <a href="#cite_ref-refGRCh38Ensembl_1-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-refGRCh38Ensembl_1-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-refGRCh38Ensembl_1-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://May2017.archive.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000005844">GRCh38: Ensembl release 89: ENSG00000005844</a> – <a href="/wiki/Ensembl_genome_database_project" title="Ensembl genome database project">Ensembl</a>, May 2017</span> </li> <li id="cite_note-refGRCm38Ensembl-2"><span class="mw-cite-backlink">^ <a href="#cite_ref-refGRCm38Ensembl_2-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-refGRCm38Ensembl_2-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-refGRCm38Ensembl_2-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://May2017.archive.ensembl.org/Mus_musculus/Gene/Summary?db=core;g=ENSMUSG00000030830">GRCm38: Ensembl release 89: ENSMUSG00000030830</a> – <a href="/wiki/Ensembl_genome_database_project" title="Ensembl genome database project">Ensembl</a>, May 2017</span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-3">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=3683">"Human PubMed Reference:"</a>. <i>National Center for Biotechnology Information, U.S. National Library of Medicine</i>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=National+Center+for+Biotechnology+Information%2C+U.S.+National+Library+of+Medicine&rft.atitle=Human+PubMed+Reference%3A&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fentrez%3Fdb%3Dgene%26cmd%3DLink%26LinkName%3Dgene_pubmed%26from_uid%3D3683&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-4">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=16408">"Mouse PubMed Reference:"</a>. <i>National Center for Biotechnology Information, U.S. National Library of Medicine</i>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=National+Center+for+Biotechnology+Information%2C+U.S.+National+Library+of+Medicine&rft.atitle=Mouse+PubMed+Reference%3A&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fentrez%3Fdb%3Dgene%26cmd%3DLink%26LinkName%3Dgene_pubmed%26from_uid%3D16408&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></span> </li> <li id="cite_note-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-5">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/gene/3683">"NCBI"</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=NCBI&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fgene%2F3683&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></span> </li> <li id="cite_note-6"><span class="mw-cite-backlink"><b><a href="#cite_ref-6">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3683">"Entrez Gene: ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)"</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Entrez+Gene%3A+ITGAL+integrin%2C+alpha+L+%28antigen+CD11A+%28p180%29%2C+lymphocyte+function-associated+antigen+1%3B+alpha+polypeptide%29&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fentrez%3FDb%3Dgene%26Cmd%3DShowDetailView%26TermToSearch%3D3683&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></span> </li> <li id="cite_note-pmid11279101-7"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid11279101_7-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLuTakagiSpringer2001" class="citation journal cs1">Lu C, Takagi J, Springer TA (May 2001). <a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.M100600200">"Association of the membrane proximal regions of the alpha and beta subunit cytoplasmic domains constrains an integrin in the inactive state"</a>. <i>J. Biol. Chem</i>. <b>276</b> (18): <span class="nowrap">14642–</span>8. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.M100600200">10.1074/jbc.M100600200</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11279101">11279101</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Biol.+Chem.&rft.atitle=Association+of+the+membrane+proximal+regions+of+the+alpha+and+beta+subunit+cytoplasmic+domains+constrains+an+integrin+in+the+inactive+state&rft.volume=276&rft.issue=18&rft.pages=%3Cspan+class%3D%22nowrap%22%3E14642-%3C%2Fspan%3E8&rft.date=2001-05&rft_id=info%3Adoi%2F10.1074%2Fjbc.M100600200&rft_id=info%3Apmid%2F11279101&rft.aulast=Lu&rft.aufirst=C&rft.au=Takagi%2C+J&rft.au=Springer%2C+TA&rft_id=https%3A%2F%2Fdoi.org%2F10.1074%252Fjbc.M100600200&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></span> </li> <li id="cite_note-pmid12526797-8"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid12526797_8-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFShimaokaXiaoLiuYang2003" class="citation journal cs1">Shimaoka M, Xiao T, Liu JH, Yang Y, Dong Y, Jun CD, McCormack A, Zhang R, Joachimiak A, Takagi J, Wang JH, Springer TA (Jan 2003). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372089">"Structures of the alpha L I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation"</a>. <i>Cell</i>. <b>112</b> (1): <span class="nowrap">99–</span>111. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0092-8674%2802%2901257-6">10.1016/S0092-8674(02)01257-6</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372089">4372089</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/12526797">12526797</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Cell&rft.atitle=Structures+of+the+alpha+L+I+domain+and+its+complex+with+ICAM-1+reveal+a+shape-shifting+pathway+for+integrin+regulation&rft.volume=112&rft.issue=1&rft.pages=%3Cspan+class%3D%22nowrap%22%3E99-%3C%2Fspan%3E111&rft.date=2003-01&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC4372089%23id-name%3DPMC&rft_id=info%3Apmid%2F12526797&rft_id=info%3Adoi%2F10.1016%2FS0092-8674%2802%2901257-6&rft.aulast=Shimaoka&rft.aufirst=M&rft.au=Xiao%2C+T&rft.au=Liu%2C+JH&rft.au=Yang%2C+Y&rft.au=Dong%2C+Y&rft.au=Jun%2C+CD&rft.au=McCormack%2C+A&rft.au=Zhang%2C+R&rft.au=Joachimiak%2C+A&rft.au=Takagi%2C+J&rft.au=Wang%2C+JH&rft.au=Springer%2C+TA&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC4372089&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></span> </li> <li id="cite_note-pmid11786177-9"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid11786177_9-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFYusuf-MakagiansarMakagiansarHuSiahaan2001" class="citation journal cs1">Yusuf-Makagiansar H, Makagiansar IT, Hu Y, Siahaan TJ (Dec 2001). "Synergistic inhibitory activity of alpha- and beta-LFA-1 peptides on LFA-1/ICAM-1 interaction". <i>Peptides</i>. <b>22</b> (12): <span class="nowrap">1955–</span>62. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0196-9781%2801%2900546-0">10.1016/S0196-9781(01)00546-0</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11786177">11786177</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:54343441">54343441</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Peptides&rft.atitle=Synergistic+inhibitory+activity+of+alpha-+and+beta-LFA-1+peptides+on+LFA-1%2FICAM-1+interaction&rft.volume=22&rft.issue=12&rft.pages=%3Cspan+class%3D%22nowrap%22%3E1955-%3C%2Fspan%3E62&rft.date=2001-12&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A54343441%23id-name%3DS2CID&rft_id=info%3Apmid%2F11786177&rft_id=info%3Adoi%2F10.1016%2FS0196-9781%2801%2900546-0&rft.aulast=Yusuf-Makagiansar&rft.aufirst=H&rft.au=Makagiansar%2C+IT&rft.au=Hu%2C+Y&rft.au=Siahaan%2C+TJ&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></span> </li> </ol></div></div> <div class="mw-heading mw-heading2"><h2 id="Further_reading">Further reading</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Integrin_alpha_L&action=edit&section=5" title="Edit section: Further reading"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239549316">.mw-parser-output .refbegin{margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}@media screen{.mw-parser-output .refbegin{font-size:90%}}</style><div class="refbegin refbegin-columns references-column-width" style="column-width: 30em"> <ul><li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLubvan_KooykFigdor1995" class="citation journal cs1">Lub M, van Kooyk Y, Figdor CG (1995). "Ins and outs of LFA-1". <i>Immunol. Today</i>. <b>16</b> (10): <span class="nowrap">479–</span>83. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2F0167-5699%2895%2980031-X">10.1016/0167-5699(95)80031-X</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/7576051">7576051</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Immunol.+Today&rft.atitle=Ins+and+outs+of+LFA-1.&rft.volume=16&rft.issue=10&rft.pages=%3Cspan+class%3D%22nowrap%22%3E479-%3C%2Fspan%3E83&rft.date=1995&rft_id=info%3Adoi%2F10.1016%2F0167-5699%2895%2980031-X&rft_id=info%3Apmid%2F7576051&rft.aulast=Lub&rft.aufirst=M&rft.au=van+Kooyk%2C+Y&rft.au=Figdor%2C+CG&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFDickesonSantoro1998" class="citation journal cs1">Dickeson SK, Santoro SA (1998). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11147323">"Ligand recognition by the I domain-containing integrins"</a>. <i>Cell. Mol. Life Sci</i>. <b>54</b> (6): <span class="nowrap">556–</span>66. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1007%2Fs000180050184">10.1007/s000180050184</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11147323">11147323</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/9676575">9676575</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:9775686">9775686</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Cell.+Mol.+Life+Sci.&rft.atitle=Ligand+recognition+by+the+I+domain-containing+integrins.&rft.volume=54&rft.issue=6&rft.pages=%3Cspan+class%3D%22nowrap%22%3E556-%3C%2Fspan%3E66&rft.date=1998&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC11147323%23id-name%3DPMC&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A9775686%23id-name%3DS2CID&rft_id=info%3Apmid%2F9676575&rft_id=info%3Adoi%2F10.1007%2Fs000180050184&rft.aulast=Dickeson&rft.aufirst=SK&rft.au=Santoro%2C+SA&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC11147323&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFPorterHogg1999" class="citation journal cs1">Porter JC, Hogg N (1999). "Integrins take partners: cross-talk between integrins and other membrane receptors". <i>Trends Cell Biol</i>. <b>8</b> (10): <span class="nowrap">390–</span>6. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0962-8924%2898%2901344-0">10.1016/S0962-8924(98)01344-0</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/9789327">9789327</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Trends+Cell+Biol.&rft.atitle=Integrins+take+partners%3A+cross-talk+between+integrins+and+other+membrane+receptors.&rft.volume=8&rft.issue=10&rft.pages=%3Cspan+class%3D%22nowrap%22%3E390-%3C%2Fspan%3E6&rft.date=1999&rft_id=info%3Adoi%2F10.1016%2FS0962-8924%2898%2901344-0&rft_id=info%3Apmid%2F9789327&rft.aulast=Porter&rft.aufirst=JC&rft.au=Hogg%2C+N&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFGiblinLemieux2006" class="citation journal cs1">Giblin PA, Lemieux RM (2006). "LFA-1 as a key regulator of immune function: approaches toward the development of LFA-1-based therapeutics". <i>Curr. Pharm. Des</i>. <b>12</b> (22): <span class="nowrap">2771–</span>95. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.2174%2F138161206777947731">10.2174/138161206777947731</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/16918410">16918410</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Curr.+Pharm.+Des.&rft.atitle=LFA-1+as+a+key+regulator+of+immune+function%3A+approaches+toward+the+development+of+LFA-1-based+therapeutics.&rft.volume=12&rft.issue=22&rft.pages=%3Cspan+class%3D%22nowrap%22%3E2771-%3C%2Fspan%3E95&rft.date=2006&rft_id=info%3Adoi%2F10.2174%2F138161206777947731&rft_id=info%3Apmid%2F16918410&rft.aulast=Giblin&rft.aufirst=PA&rft.au=Lemieux%2C+RM&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMaurerHolterMajdicFischer1991" class="citation journal cs1">Maurer D, Holter W, Majdic O, Fischer GF, Knapp W (1991). "CD27 expression by a distinct subpopulation of human B lymphocytes". <i>Eur. J. Immunol</i>. <b>20</b> (12): <span class="nowrap">2679–</span>84. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1002%2Feji.1830201223">10.1002/eji.1830201223</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/1702722">1702722</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:9794163">9794163</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Eur.+J.+Immunol.&rft.atitle=CD27+expression+by+a+distinct+subpopulation+of+human+B+lymphocytes.&rft.volume=20&rft.issue=12&rft.pages=%3Cspan+class%3D%22nowrap%22%3E2679-%3C%2Fspan%3E84&rft.date=1991&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A9794163%23id-name%3DS2CID&rft_id=info%3Apmid%2F1702722&rft_id=info%3Adoi%2F10.1002%2Feji.1830201223&rft.aulast=Maurer&rft.aufirst=D&rft.au=Holter%2C+W&rft.au=Majdic%2C+O&rft.au=Fischer%2C+GF&rft.au=Knapp%2C+W&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFKalterGendelmanMeltzer1992" class="citation journal cs1">Kalter DC, <a href="/wiki/Howard_E._Gendelman" title="Howard E. Gendelman">Gendelman HE</a>, Meltzer MS (1992). "Inhibition of human immunodeficiency virus infection in monocytes by monoclonal antibodies against leukocyte adhesion molecules". <i>Immunol. Lett</i>. <b>30</b> (2): <span class="nowrap">219–</span>27. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2F0165-2478%2891%2990029-A">10.1016/0165-2478(91)90029-A</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/1757107">1757107</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Immunol.+Lett.&rft.atitle=Inhibition+of+human+immunodeficiency+virus+infection+in+monocytes+by+monoclonal+antibodies+against+leukocyte+adhesion+molecules.&rft.volume=30&rft.issue=2&rft.pages=%3Cspan+class%3D%22nowrap%22%3E219-%3C%2Fspan%3E27&rft.date=1992&rft_id=info%3Adoi%2F10.1016%2F0165-2478%2891%2990029-A&rft_id=info%3Apmid%2F1757107&rft.aulast=Kalter&rft.aufirst=DC&rft.au=Gendelman%2C+HE&rft.au=Meltzer%2C+MS&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFAlvarezPulidoCampaneroParaiso1992" class="citation journal cs1">Alvarez V, Pulido R, Campanero MR, Paraiso V, de Landázuri MO, Sánchez-Madrid F (1992). <a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fki.1991.291">"Differentially regulated cell surface expression of leukocyte adhesion receptors on neutrophils"</a>. <i>Kidney Int</i>. <b>40</b> (5): <span class="nowrap">899–</span>905. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fki.1991.291">10.1038/ki.1991.291</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/1762294">1762294</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Kidney+Int.&rft.atitle=Differentially+regulated+cell+surface+expression+of+leukocyte+adhesion+receptors+on+neutrophils.&rft.volume=40&rft.issue=5&rft.pages=%3Cspan+class%3D%22nowrap%22%3E899-%3C%2Fspan%3E905&rft.date=1992&rft_id=info%3Adoi%2F10.1038%2Fki.1991.291&rft_id=info%3Apmid%2F1762294&rft.aulast=Alvarez&rft.aufirst=V&rft.au=Pulido%2C+R&rft.au=Campanero%2C+MR&rft.au=Paraiso%2C+V&rft.au=de+Land%C3%A1zuri%2C+MO&rft.au=S%C3%A1nchez-Madrid%2C+F&rft_id=https%3A%2F%2Fdoi.org%2F10.1038%252Fki.1991.291&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFValentinLundinPatarroyoAsjö1990" class="citation journal cs1">Valentin A, Lundin K, Patarroyo M, Asjö B (1990). <a rel="nofollow" class="external text" href="https://doi.org/10.4049%2Fjimmunol.144.3.934">"The leukocyte adhesion glycoprotein CD18 participates in HIV-1-induced syncytia formation in monocytoid and T cells"</a>. <i>J. Immunol</i>. <b>144</b> (3): <span class="nowrap">934–</span>7. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.4049%2Fjimmunol.144.3.934">10.4049/jimmunol.144.3.934</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/1967280">1967280</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Immunol.&rft.atitle=The+leukocyte+adhesion+glycoprotein+CD18+participates+in+HIV-1-induced+syncytia+formation+in+monocytoid+and+T+cells.&rft.volume=144&rft.issue=3&rft.pages=%3Cspan+class%3D%22nowrap%22%3E934-%3C%2Fspan%3E7&rft.date=1990&rft_id=info%3Adoi%2F10.4049%2Fjimmunol.144.3.934&rft_id=info%3Apmid%2F1967280&rft.aulast=Valentin&rft.aufirst=A&rft.au=Lundin%2C+K&rft.au=Patarroyo%2C+M&rft.au=Asj%C3%B6%2C+B&rft_id=https%3A%2F%2Fdoi.org%2F10.4049%252Fjimmunol.144.3.934&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLarsonCorbiBermanSpringer1989" class="citation journal cs1">Larson RS, Corbi AL, Berman L, Springer T (1989). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2115430">"Primary structure of the leukocyte function-associated molecule-1 alpha subunit: an integrin with an embedded domain defining a protein superfamily"</a>. <i>J. Cell Biol</i>. <b>108</b> (2): <span class="nowrap">703–</span>12. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1083%2Fjcb.108.2.703">10.1083/jcb.108.2.703</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2115430">2115430</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/2537322">2537322</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Cell+Biol.&rft.atitle=Primary+structure+of+the+leukocyte+function-associated+molecule-1+alpha+subunit%3A+an+integrin+with+an+embedded+domain+defining+a+protein+superfamily&rft.volume=108&rft.issue=2&rft.pages=%3Cspan+class%3D%22nowrap%22%3E703-%3C%2Fspan%3E12&rft.date=1989&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2115430%23id-name%3DPMC&rft_id=info%3Apmid%2F2537322&rft_id=info%3Adoi%2F10.1083%2Fjcb.108.2.703&rft.aulast=Larson&rft.aufirst=RS&rft.au=Corbi%2C+AL&rft.au=Berman%2C+L&rft.au=Springer%2C+T&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2115430&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFHildrethOrentas1989" class="citation journal cs1">Hildreth JE, Orentas RJ (1989). "Involvement of a leukocyte adhesion receptor (LFA-1) in HIV-induced syncytium formation". <i>Science</i>. <b>244</b> (4908): <span class="nowrap">1075–</span>8. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/1989Sci...244.1075H">1989Sci...244.1075H</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1126%2Fscience.2543075">10.1126/science.2543075</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/2543075">2543075</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Science&rft.atitle=Involvement+of+a+leukocyte+adhesion+receptor+%28LFA-1%29+in+HIV-induced+syncytium+formation&rft.volume=244&rft.issue=4908&rft.pages=%3Cspan+class%3D%22nowrap%22%3E1075-%3C%2Fspan%3E8&rft.date=1989&rft_id=info%3Apmid%2F2543075&rft_id=info%3Adoi%2F10.1126%2Fscience.2543075&rft_id=info%3Abibcode%2F1989Sci...244.1075H&rft.aulast=Hildreth&rft.aufirst=JE&rft.au=Orentas%2C+RJ&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFSandersMakgobaSharrowStephany1988" class="citation journal cs1">Sanders ME, Makgoba MW, Sharrow SO, Stephany D, Springer TA, Young HA, Shaw S (1988). <a rel="nofollow" class="external text" href="https://doi.org/10.4049%2Fjimmunol.140.5.1401">"Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN-gamma production"</a>. <i>J. Immunol</i>. <b>140</b> (5): <span class="nowrap">1401–</span>7. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.4049%2Fjimmunol.140.5.1401">10.4049/jimmunol.140.5.1401</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/2894392">2894392</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Immunol.&rft.atitle=Human+memory+T+lymphocytes+express+increased+levels+of+three+cell+adhesion+molecules+%28LFA-3%2C+CD2%2C+and+LFA-1%29+and+three+other+molecules+%28UCHL1%2C+CDw29%2C+and+Pgp-1%29+and+have+enhanced+IFN-gamma+production&rft.volume=140&rft.issue=5&rft.pages=%3Cspan+class%3D%22nowrap%22%3E1401-%3C%2Fspan%3E7&rft.date=1988&rft_id=info%3Adoi%2F10.4049%2Fjimmunol.140.5.1401&rft_id=info%3Apmid%2F2894392&rft.aulast=Sanders&rft.aufirst=ME&rft.au=Makgoba%2C+MW&rft.au=Sharrow%2C+SO&rft.au=Stephany%2C+D&rft.au=Springer%2C+TA&rft.au=Young%2C+HA&rft.au=Shaw%2C+S&rft_id=https%3A%2F%2Fdoi.org%2F10.4049%252Fjimmunol.140.5.1401&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFCorbiLarsonKishimotoSpringer1988" class="citation journal cs1">Corbi AL, Larson RS, Kishimoto TK, Springer TA, Morton CC (1988). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188934">"Chromosomal location of the genes encoding the leukocyte adhesion receptors LFA-1, Mac-1 and p150,95. Identification of a gene cluster involved in cell adhesion"</a>. <i>J. Exp. Med</i>. <b>167</b> (5): <span class="nowrap">1597–</span>607. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1084%2Fjem.167.5.1597">10.1084/jem.167.5.1597</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188934">2188934</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/3284962">3284962</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Exp.+Med.&rft.atitle=Chromosomal+location+of+the+genes+encoding+the+leukocyte+adhesion+receptors+LFA-1%2C+Mac-1+and+p150%2C95.+Identification+of+a+gene+cluster+involved+in+cell+adhesion&rft.volume=167&rft.issue=5&rft.pages=%3Cspan+class%3D%22nowrap%22%3E1597-%3C%2Fspan%3E607&rft.date=1988&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2188934%23id-name%3DPMC&rft_id=info%3Apmid%2F3284962&rft_id=info%3Adoi%2F10.1084%2Fjem.167.5.1597&rft.aulast=Corbi&rft.aufirst=AL&rft.au=Larson%2C+RS&rft.au=Kishimoto%2C+TK&rft.au=Springer%2C+TA&rft.au=Morton%2C+CC&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2188934&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFte_VeldeKeizerFigdor1987" class="citation journal cs1">te Velde AA, Keizer GD, Figdor CG (1987). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1453405">"Differential function of LFA-1 family molecules (CD11 and CD18) in adhesion of human monocytes to melanoma and endothelial cells"</a>. <i>Immunology</i>. <b>61</b> (3): <span class="nowrap">261–</span>7. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1453405">1453405</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/3301632">3301632</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Immunology&rft.atitle=Differential+function+of+LFA-1+family+molecules+%28CD11+and+CD18%29+in+adhesion+of+human+monocytes+to+melanoma+and+endothelial+cells&rft.volume=61&rft.issue=3&rft.pages=%3Cspan+class%3D%22nowrap%22%3E261-%3C%2Fspan%3E7&rft.date=1987&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1453405%23id-name%3DPMC&rft_id=info%3Apmid%2F3301632&rft.aulast=te+Velde&rft.aufirst=AA&rft.au=Keizer%2C+GD&rft.au=Figdor%2C+CG&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1453405&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFQuLeahy1995" class="citation journal cs1">Qu A, Leahy DJ (1995). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC40779">"Crystal structure of the I-domain from the CD11a/CD18 (LFA-1, alpha L beta 2) integrin"</a>. <i>Proc. Natl. Acad. Sci. U.S.A</i>. <b>92</b> (22): <span class="nowrap">10277–</span>81. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/1995PNAS...9210277Q">1995PNAS...9210277Q</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1073%2Fpnas.92.22.10277">10.1073/pnas.92.22.10277</a></span>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC40779">40779</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/7479767">7479767</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proc.+Natl.+Acad.+Sci.+U.S.A.&rft.atitle=Crystal+structure+of+the+I-domain+from+the+CD11a%2FCD18+%28LFA-1%2C+alpha+L+beta+2%29+integrin&rft.volume=92&rft.issue=22&rft.pages=%3Cspan+class%3D%22nowrap%22%3E10277-%3C%2Fspan%3E81&rft.date=1995&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC40779%23id-name%3DPMC&rft_id=info%3Apmid%2F7479767&rft_id=info%3Adoi%2F10.1073%2Fpnas.92.22.10277&rft_id=info%3Abibcode%2F1995PNAS...9210277Q&rft.aulast=Qu&rft.aufirst=A&rft.au=Leahy%2C+DJ&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC40779&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFTurnerMcIlwaineAnthonyParker1995" class="citation journal cs1">Turner ML, McIlwaine K, Anthony RS, Parker AC (1995). "Differential expression of cell adhesion molecules by human hematopoietic progenitor cells from bone marrow and mobilized adult peripheral blood". <i>Stem Cells</i>. <b>13</b> (3): <span class="nowrap">311–</span>6. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1002%2Fstem.5530130312">10.1002/stem.5530130312</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/7542116">7542116</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:21373771">21373771</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Stem+Cells&rft.atitle=Differential+expression+of+cell+adhesion+molecules+by+human+hematopoietic+progenitor+cells+from+bone+marrow+and+mobilized+adult+peripheral+blood&rft.volume=13&rft.issue=3&rft.pages=%3Cspan+class%3D%22nowrap%22%3E311-%3C%2Fspan%3E6&rft.date=1995&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A21373771%23id-name%3DS2CID&rft_id=info%3Apmid%2F7542116&rft_id=info%3Adoi%2F10.1002%2Fstem.5530130312&rft.aulast=Turner&rft.aufirst=ML&rft.au=McIlwaine%2C+K&rft.au=Anthony%2C+RS&rft.au=Parker%2C+AC&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMarzuschRuckGeiselhartHandgretinger1993" class="citation journal cs1">Marzusch K, Ruck P, Geiselhart A, Handgretinger R, Dietl JA, Kaiserling E, Horny HP, Vince G, Redman CW (1993). "Distribution of cell adhesion molecules on CD56++, CD3-, CD16- large granular lymphocytes and endothelial cells in first-trimester human decidua". <i>Hum. Reprod</i>. <b>8</b> (8): <span class="nowrap">1203–</span>8. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Foxfordjournals.humrep.a138229">10.1093/oxfordjournals.humrep.a138229</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/7691868">7691868</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Hum.+Reprod.&rft.atitle=Distribution+of+cell+adhesion+molecules+on+CD56%2B%2B%2C+CD3-%2C+CD16-+large+granular+lymphocytes+and+endothelial+cells+in+first-trimester+human+decidua&rft.volume=8&rft.issue=8&rft.pages=%3Cspan+class%3D%22nowrap%22%3E1203-%3C%2Fspan%3E8&rft.date=1993&rft_id=info%3Adoi%2F10.1093%2Foxfordjournals.humrep.a138229&rft_id=info%3Apmid%2F7691868&rft.aulast=Marzusch&rft.aufirst=K&rft.au=Ruck%2C+P&rft.au=Geiselhart%2C+A&rft.au=Handgretinger%2C+R&rft.au=Dietl%2C+JA&rft.au=Kaiserling%2C+E&rft.au=Horny%2C+HP&rft.au=Vince%2C+G&rft.au=Redman%2C+CW&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFCapobianchiAmeglioCordiali_FeiCastilletti1994" class="citation journal cs1">Capobianchi MR, Ameglio F, Cordiali Fei P, Castilletti C, Mercuri F, Fais S, Dianzani F (1994). "Coordinate induction of interferon alpha and gamma by recombinant HIV-1 glycoprotein 120". <i>AIDS Res. Hum. Retroviruses</i>. <b>9</b> (10): <span class="nowrap">957–</span>62. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1089%2Faid.1993.9.957">10.1089/aid.1993.9.957</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/7904170">7904170</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=AIDS+Res.+Hum.+Retroviruses&rft.atitle=Coordinate+induction+of+interferon+alpha+and+gamma+by+recombinant+HIV-1+glycoprotein+120&rft.volume=9&rft.issue=10&rft.pages=%3Cspan+class%3D%22nowrap%22%3E957-%3C%2Fspan%3E62&rft.date=1994&rft_id=info%3Adoi%2F10.1089%2Faid.1993.9.957&rft_id=info%3Apmid%2F7904170&rft.aulast=Capobianchi&rft.aufirst=MR&rft.au=Ameglio%2C+F&rft.au=Cordiali+Fei%2C+P&rft.au=Castilletti%2C+C&rft.au=Mercuri%2C+F&rft.au=Fais%2C+S&rft.au=Dianzani%2C+F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBermanNakamura1994" class="citation journal cs1">Berman PW, Nakamura GR (1994). "Adhesion mediated by intercellular adhesion molecule 1 attenuates the potency of antibodies that block HIV-1 gp160-dependent syncytium formation". <i>AIDS Res. Hum. Retroviruses</i>. <b>10</b> (5): <span class="nowrap">585–</span>93. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1089%2Faid.1994.10.585">10.1089/aid.1994.10.585</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/7917519">7917519</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=AIDS+Res.+Hum.+Retroviruses&rft.atitle=Adhesion+mediated+by+intercellular+adhesion+molecule+1+attenuates+the+potency+of+antibodies+that+block+HIV-1+gp160-dependent+syncytium+formation&rft.volume=10&rft.issue=5&rft.pages=%3Cspan+class%3D%22nowrap%22%3E585-%3C%2Fspan%3E93&rft.date=1994&rft_id=info%3Adoi%2F10.1089%2Faid.1994.10.585&rft_id=info%3Apmid%2F7917519&rft.aulast=Berman&rft.aufirst=PW&rft.au=Nakamura%2C+GR&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFChirmuleOyaizuSaxingerPahwa1994" class="citation journal cs1">Chirmule N, Oyaizu N, Saxinger C, Pahwa S (1994). <a rel="nofollow" class="external text" href="https://zenodo.org/record/1234770">"Nef protein of HIV-1 has B-cell stimulatory activity"</a>. <i>AIDS</i>. <b>8</b> (6): <span class="nowrap">733–</span>4. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1097%2F00002030-199406000-00002">10.1097/00002030-199406000-00002</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/8086129">8086129</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:36774740">36774740</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=AIDS&rft.atitle=Nef+protein+of+HIV-1+has+B-cell+stimulatory+activity&rft.volume=8&rft.issue=6&rft.pages=%3Cspan+class%3D%22nowrap%22%3E733-%3C%2Fspan%3E4&rft.date=1994&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A36774740%23id-name%3DS2CID&rft_id=info%3Apmid%2F8086129&rft_id=info%3Adoi%2F10.1097%2F00002030-199406000-00002&rft.aulast=Chirmule&rft.aufirst=N&rft.au=Oyaizu%2C+N&rft.au=Saxinger%2C+C&rft.au=Pahwa%2C+S&rft_id=https%3A%2F%2Fzenodo.org%2Frecord%2F1234770&rfr_id=info%3Asid%2Fen.wikipedia.org%3AIntegrin+alpha+L" class="Z3988"></span></li></ul> </div> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r1129693374">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output .hlist.inline,.mw-parser-output .hlist.inline dl,.mw-parser-output .hlist.inline ol,.mw-parser-output .hlist.inline ul,.mw-parser-output .hlist dl dl,.mw-parser-output .hlist dl ol,.mw-parser-output .hlist dl ul,.mw-parser-output .hlist ol dl,.mw-parser-output .hlist ol ol,.mw-parser-output .hlist ol ul,.mw-parser-output .hlist ul dl,.mw-parser-output .hlist ul ol,.mw-parser-output .hlist ul ul{display:inline}.mw-parser-output .hlist .mw-empty-li{display:none}.mw-parser-output .hlist dt::after{content:": "}.mw-parser-output .hlist dd::after,.mw-parser-output .hlist li::after{content:" · ";font-weight:bold}.mw-parser-output .hlist dd:last-child::after,.mw-parser-output .hlist dt:last-child::after,.mw-parser-output .hlist li:last-child::after{content:none}.mw-parser-output .hlist dd dd:first-child::before,.mw-parser-output .hlist dd dt:first-child::before,.mw-parser-output .hlist dd li:first-child::before,.mw-parser-output .hlist dt dd:first-child::before,.mw-parser-output .hlist dt dt:first-child::before,.mw-parser-output .hlist dt li:first-child::before,.mw-parser-output .hlist li dd:first-child::before,.mw-parser-output .hlist li dt:first-child::before,.mw-parser-output .hlist li li:first-child::before{content:" (";font-weight:normal}.mw-parser-output .hlist dd dd:last-child::after,.mw-parser-output .hlist dd dt:last-child::after,.mw-parser-output .hlist dd li:last-child::after,.mw-parser-output .hlist dt dd:last-child::after,.mw-parser-output .hlist dt dt:last-child::after,.mw-parser-output .hlist dt li:last-child::after,.mw-parser-output .hlist li dd:last-child::after,.mw-parser-output .hlist li dt:last-child::after,.mw-parser-output .hlist li li:last-child::after{content:")";font-weight:normal}.mw-parser-output .hlist ol{counter-reset:listitem}.mw-parser-output .hlist ol>li{counter-increment:listitem}.mw-parser-output .hlist ol>li::before{content:" "counter(listitem)"\a0 "}.mw-parser-output .hlist dd ol>li:first-child::before,.mw-parser-output .hlist dt ol>li:first-child::before,.mw-parser-output .hlist li ol>li:first-child::before{content:" ("counter(listitem)"\a0 "}</style><style data-mw-deduplicate="TemplateStyles:r1236075235">.mw-parser-output .navbox{box-sizing:border-box;border:1px solid #a2a9b1;width:100%;clear:both;font-size:88%;text-align:center;padding:1px;margin:1em auto 0}.mw-parser-output .navbox .navbox{margin-top:0}.mw-parser-output .navbox+.navbox,.mw-parser-output .navbox+.navbox-styles+.navbox{margin-top:-1px}.mw-parser-output .navbox-inner,.mw-parser-output .navbox-subgroup{width:100%}.mw-parser-output .navbox-group,.mw-parser-output .navbox-title,.mw-parser-output .navbox-abovebelow{padding:0.25em 1em;line-height:1.5em;text-align:center}.mw-parser-output .navbox-group{white-space:nowrap;text-align:right}.mw-parser-output .navbox,.mw-parser-output .navbox-subgroup{background-color:#fdfdfd}.mw-parser-output .navbox-list{line-height:1.5em;border-color:#fdfdfd}.mw-parser-output .navbox-list-with-group{text-align:left;border-left-width:2px;border-left-style:solid}.mw-parser-output tr+tr>.navbox-abovebelow,.mw-parser-output tr+tr>.navbox-group,.mw-parser-output tr+tr>.navbox-image,.mw-parser-output tr+tr>.navbox-list{border-top:2px solid #fdfdfd}.mw-parser-output .navbox-title{background-color:#ccf}.mw-parser-output .navbox-abovebelow,.mw-parser-output .navbox-group,.mw-parser-output .navbox-subgroup .navbox-title{background-color:#ddf}.mw-parser-output .navbox-subgroup .navbox-group,.mw-parser-output .navbox-subgroup .navbox-abovebelow{background-color:#e6e6ff}.mw-parser-output .navbox-even{background-color:#f7f7f7}.mw-parser-output .navbox-odd{background-color:transparent}.mw-parser-output .navbox .hlist td dl,.mw-parser-output .navbox .hlist td ol,.mw-parser-output .navbox .hlist td ul,.mw-parser-output .navbox td.hlist dl,.mw-parser-output .navbox td.hlist ol,.mw-parser-output .navbox td.hlist ul{padding:0.125em 0}.mw-parser-output .navbox .navbar{display:block;font-size:100%}.mw-parser-output .navbox-title .navbar{float:left;text-align:left;margin-right:0.5em}body.skin--responsive .mw-parser-output .navbox-image img{max-width:none!important}@media print{body.ns-0 .mw-parser-output .navbox{display:none!important}}</style></div><div role="navigation" class="navbox" aria-labelledby="PDB_gallery11" style="padding:3px"><table class="nowraplinks mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="background:#e7dcc3;color:inherit;"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><style data-mw-deduplicate="TemplateStyles:r1239400231">.mw-parser-output .navbar{display:inline;font-size:88%;font-weight:normal}.mw-parser-output .navbar-collapse{float:left;text-align:left}.mw-parser-output .navbar-boxtext{word-spacing:0}.mw-parser-output .navbar ul{display:inline-block;white-space:nowrap;line-height:inherit}.mw-parser-output .navbar-brackets::before{margin-right:-0.125em;content:"[ "}.mw-parser-output .navbar-brackets::after{margin-left:-0.125em;content:" ]"}.mw-parser-output .navbar li{word-spacing:-0.125em}.mw-parser-output .navbar a>span,.mw-parser-output .navbar a>abbr{text-decoration:inherit}.mw-parser-output .navbar-mini abbr{font-variant:small-caps;border-bottom:none;text-decoration:none;cursor:inherit}.mw-parser-output .navbar-ct-full{font-size:114%;margin:0 7em}.mw-parser-output .navbar-ct-mini{font-size:114%;margin:0 4em}html.skin-theme-clientpref-night .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}@media(prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}}@media print{.mw-parser-output .navbar{display:none!important}}</style><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:PDB_Gallery" title="Template:PDB Gallery"><abbr title="View this template" style="color:inherit">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:PDB_Gallery" title="Template talk:PDB Gallery"><abbr title="Discuss this template" style="color:inherit">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:PDB_Gallery" title="Special:EditPage/Template:PDB Gallery"><abbr title="Edit this template" style="color:inherit">e</abbr></a></li></ul></div><div id="PDB_gallery11" style="font-size:114%;margin:0 4em">PDB gallery</div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><ul class="gallery mw-gallery-traditional nochecker" style="line-height:130%"> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1cqp_EBI.jpg" class="mw-file-description" title="1cqp: CRYSTAL STRUCTURE ANALYSIS OF THE COMPLEX LFA-1 (CD11A) I-DOMAIN / LOVASTATIN AT 2.6 A RESOLUTION"><img alt="1cqp: CRYSTAL STRUCTURE ANALYSIS OF THE COMPLEX LFA-1 (CD11A) I-DOMAIN / LOVASTATIN AT 2.6 A RESOLUTION" src="//upload.wikimedia.org/wikipedia/commons/thumb/b/bd/PDB_1cqp_EBI.jpg/180px-PDB_1cqp_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/bd/PDB_1cqp_EBI.jpg/270px-PDB_1cqp_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/bd/PDB_1cqp_EBI.jpg/360px-PDB_1cqp_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1cqp</b>: CRYSTAL STRUCTURE ANALYSIS OF THE COMPLEX LFA-1 (CD11A) I-DOMAIN / LOVASTATIN AT 2.6 A RESOLUTION</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1dgq_EBI.jpg" class="mw-file-description" title="1dgq: NMR SOLUTION STRUCTURE OF THE INSERTED DOMAIN OF HUMAN LEUKOCYTE FUNCTION ASSOCIATED ANTIGEN-1"><img alt="1dgq: NMR SOLUTION STRUCTURE OF THE INSERTED DOMAIN OF HUMAN LEUKOCYTE FUNCTION ASSOCIATED ANTIGEN-1" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/de/PDB_1dgq_EBI.jpg/180px-PDB_1dgq_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/de/PDB_1dgq_EBI.jpg/270px-PDB_1dgq_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/de/PDB_1dgq_EBI.jpg/360px-PDB_1dgq_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1dgq</b>: NMR SOLUTION STRUCTURE OF THE INSERTED DOMAIN OF HUMAN LEUKOCYTE FUNCTION ASSOCIATED ANTIGEN-1</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1lfa_EBI.jpg" class="mw-file-description" title="1lfa: CD11A I-DOMAIN WITH BOUND MN++"><img alt="1lfa: CD11A I-DOMAIN WITH BOUND MN++" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/36/PDB_1lfa_EBI.jpg/180px-PDB_1lfa_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/36/PDB_1lfa_EBI.jpg/270px-PDB_1lfa_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/36/PDB_1lfa_EBI.jpg/360px-PDB_1lfa_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1lfa</b>: CD11A I-DOMAIN WITH BOUND MN++</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1mjn_EBI.jpg" class="mw-file-description" title="1mjn: Crystal Structure of the intermediate affinity aL I domain mutant"><img alt="1mjn: Crystal Structure of the intermediate affinity aL I domain mutant" src="//upload.wikimedia.org/wikipedia/commons/thumb/9/93/PDB_1mjn_EBI.jpg/180px-PDB_1mjn_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/9/93/PDB_1mjn_EBI.jpg/270px-PDB_1mjn_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/9/93/PDB_1mjn_EBI.jpg/360px-PDB_1mjn_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1mjn</b>: Crystal Structure of the intermediate affinity aL I domain mutant</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1mq8_EBI.jpg" class="mw-file-description" title="1mq8: Crystal structure of alphaL I domain in complex with ICAM-1"><img alt="1mq8: Crystal structure of alphaL I domain in complex with ICAM-1" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/ec/PDB_1mq8_EBI.jpg/180px-PDB_1mq8_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/ec/PDB_1mq8_EBI.jpg/270px-PDB_1mq8_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/ec/PDB_1mq8_EBI.jpg/360px-PDB_1mq8_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1mq8</b>: Crystal structure of alphaL I domain in complex with ICAM-1</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1mq9_EBI.jpg" class="mw-file-description" title="1mq9: Crystal structure of high affinity alphaL I domain with ligand mimetic crystal contact"><img alt="1mq9: Crystal structure of high affinity alphaL I domain with ligand mimetic crystal contact" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/43/PDB_1mq9_EBI.jpg/180px-PDB_1mq9_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/43/PDB_1mq9_EBI.jpg/270px-PDB_1mq9_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/43/PDB_1mq9_EBI.jpg/360px-PDB_1mq9_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1mq9</b>: Crystal structure of high affinity alphaL I domain with ligand mimetic crystal contact</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1mqa_EBI.jpg" class="mw-file-description" title="1mqa: Crystal structure of high affinity alphaL I domain in the absence of ligand or metal"><img alt="1mqa: Crystal structure of high affinity alphaL I domain in the absence of ligand or metal" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/71/PDB_1mqa_EBI.jpg/180px-PDB_1mqa_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/71/PDB_1mqa_EBI.jpg/270px-PDB_1mqa_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/71/PDB_1mqa_EBI.jpg/360px-PDB_1mqa_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1mqa</b>: Crystal structure of high affinity alphaL I domain in the absence of ligand or metal</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1rd4_EBI.jpg" class="mw-file-description" title="1rd4: An allosteric inhibitor of LFA-1 bound to its I-domain"><img alt="1rd4: An allosteric inhibitor of LFA-1 bound to its I-domain" src="//upload.wikimedia.org/wikipedia/commons/thumb/b/bc/PDB_1rd4_EBI.jpg/180px-PDB_1rd4_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/bc/PDB_1rd4_EBI.jpg/270px-PDB_1rd4_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/bc/PDB_1rd4_EBI.jpg/360px-PDB_1rd4_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1rd4</b>: An allosteric inhibitor of LFA-1 bound to its I-domain</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1t0p_EBI.png" class="mw-file-description" title="1t0p: Structural Basis of ICAM recognition by integrin alpahLbeta2 revealed in the complex structure of binding domains of ICAM-3 and alphaLbeta2 at 1.65 A"><img alt="1t0p: Structural Basis of ICAM recognition by integrin alpahLbeta2 revealed in the complex structure of binding domains of ICAM-3 and alphaLbeta2 at 1.65 A" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/74/PDB_1t0p_EBI.png/180px-PDB_1t0p_EBI.png" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/74/PDB_1t0p_EBI.png/270px-PDB_1t0p_EBI.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/74/PDB_1t0p_EBI.png/360px-PDB_1t0p_EBI.png 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1t0p</b>: Structural Basis of ICAM recognition by integrin alpahLbeta2 revealed in the complex structure of binding domains of ICAM-3 and alphaLbeta2 at 1.65 A</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1xdd_EBI.jpg" class="mw-file-description" title="1xdd: X-ray structure of LFA-1 I-domain in complex with LFA703 at 2.2A resolution"><img alt="1xdd: X-ray structure of LFA-1 I-domain in complex with LFA703 at 2.2A resolution" src="//upload.wikimedia.org/wikipedia/commons/thumb/9/9a/PDB_1xdd_EBI.jpg/180px-PDB_1xdd_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/9/9a/PDB_1xdd_EBI.jpg/270px-PDB_1xdd_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/9/9a/PDB_1xdd_EBI.jpg/360px-PDB_1xdd_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1xdd</b>: X-ray structure of LFA-1 I-domain in complex with LFA703 at 2.2A resolution</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1xdg_EBI.jpg" class="mw-file-description" title="1xdg: X-ray structure of LFA-1 I-domain in complex with LFA878 at 2.1A resolution"><img alt="1xdg: X-ray structure of LFA-1 I-domain in complex with LFA878 at 2.1A resolution" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e4/PDB_1xdg_EBI.jpg/180px-PDB_1xdg_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e4/PDB_1xdg_EBI.jpg/270px-PDB_1xdg_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e4/PDB_1xdg_EBI.jpg/360px-PDB_1xdg_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1xdg</b>: X-ray structure of LFA-1 I-domain in complex with LFA878 at 2.1A resolution</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1xuo_EBI.jpg" class="mw-file-description" title="1xuo: X-ray structure of LFA-1 I-domain bound to a 1,4-diazepane-2,5-dione inhibitor at 1.8A resolution"><img alt="1xuo: X-ray structure of LFA-1 I-domain bound to a 1,4-diazepane-2,5-dione inhibitor at 1.8A resolution" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/30/PDB_1xuo_EBI.jpg/180px-PDB_1xuo_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/30/PDB_1xuo_EBI.jpg/270px-PDB_1xuo_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/30/PDB_1xuo_EBI.jpg/360px-PDB_1xuo_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1xuo</b>: X-ray structure of LFA-1 I-domain bound to a 1,4-diazepane-2,5-dione inhibitor at 1.8A resolution</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1zon_EBI.jpg" class="mw-file-description" title="1zon: CD11A I-DOMAIN WITHOUT BOUND CATION"><img alt="1zon: CD11A I-DOMAIN WITHOUT BOUND CATION" src="//upload.wikimedia.org/wikipedia/commons/thumb/c/c9/PDB_1zon_EBI.jpg/180px-PDB_1zon_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/c/c9/PDB_1zon_EBI.jpg/270px-PDB_1zon_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/c/c9/PDB_1zon_EBI.jpg/360px-PDB_1zon_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1zon</b>: CD11A I-DOMAIN WITHOUT BOUND CATION</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1zoo_EBI.jpg" class="mw-file-description" title="1zoo: CD11A I-DOMAIN WITH BOUND MAGNESIUM ION"><img alt="1zoo: CD11A I-DOMAIN WITH BOUND MAGNESIUM ION" src="//upload.wikimedia.org/wikipedia/commons/thumb/5/57/PDB_1zoo_EBI.jpg/180px-PDB_1zoo_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/57/PDB_1zoo_EBI.jpg/270px-PDB_1zoo_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/57/PDB_1zoo_EBI.jpg/360px-PDB_1zoo_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1zoo</b>: CD11A I-DOMAIN WITH BOUND MAGNESIUM ION</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1zop_EBI.jpg" class="mw-file-description" title="1zop: CD11A I-DOMAIN WITH BOUND MAGNESIUM ION"><img alt="1zop: CD11A I-DOMAIN WITH BOUND MAGNESIUM ION" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/PDB_1zop_EBI.jpg/180px-PDB_1zop_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/PDB_1zop_EBI.jpg/270px-PDB_1zop_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4a/PDB_1zop_EBI.jpg/360px-PDB_1zop_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1zop</b>: CD11A I-DOMAIN WITH BOUND MAGNESIUM ION</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_2ica_EBI.jpg" class="mw-file-description" title="2ica: CD11a (LFA1) I-domain complexed with BMS-587101 aka 5-[(5S, 9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro [4.4]non-7-yl]methyl]-3-thiophenecarboxylicacid"><img alt="2ica: CD11a (LFA1) I-domain complexed with BMS-587101 aka 5-[(5S, 9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro [4.4]non-7-yl]methyl]-3-thiophenecarboxylicacid" src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a2/PDB_2ica_EBI.jpg/180px-PDB_2ica_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a2/PDB_2ica_EBI.jpg/270px-PDB_2ica_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a2/PDB_2ica_EBI.jpg/360px-PDB_2ica_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>2ica</b>: CD11a (LFA1) I-domain complexed with BMS-587101 aka 5-[(5S, 9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro [4.4]non-7-yl]methyl]-3-thiophenecarboxylicacid</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_2o7n_EBI.jpg" class="mw-file-description" title="2o7n: CD11A (LFA1) I-domain complexed with 7A-[(4-cyanophenyl)methyl]-6-(3,5-dichlorophenyl)-5-oxo-2,3,5,7A-tetrahydro-1H-pyrrolo[1,2-A]pyrrole-7-carbonitrile"><img alt="2o7n: CD11A (LFA1) I-domain complexed with 7A-[(4-cyanophenyl)methyl]-6-(3,5-dichlorophenyl)-5-oxo-2,3,5,7A-tetrahydro-1H-pyrrolo[1,2-A]pyrrole-7-carbonitrile" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/f8/PDB_2o7n_EBI.jpg/180px-PDB_2o7n_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/f8/PDB_2o7n_EBI.jpg/270px-PDB_2o7n_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/f8/PDB_2o7n_EBI.jpg/360px-PDB_2o7n_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>2o7n</b>: CD11A (LFA1) I-domain complexed with 7A-[(4-cyanophenyl)methyl]-6-(3,5-dichlorophenyl)-5-oxo-2,3,5,7A-tetrahydro-1H-pyrrolo[1,2-A]pyrrole-7-carbonitrile</div> </li> </ul></div></td></tr></tbody></table></div> <div class="mw-heading mw-heading2"><h2 id="External_links">External links</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Integrin_alpha_L&action=edit&section=6" title="Edit section: External links"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a rel="nofollow" class="external text" href="https://meshb.nlm.nih.gov/record/ui?name=CD11a+Antigen">CD11a+Antigen</a> at the U.S. National Library of Medicine <a href="/wiki/Medical_Subject_Headings" title="Medical Subject Headings">Medical Subject Headings</a> (MeSH)</li> <li><a rel="nofollow" class="external text" href="https://archive.today/20130414123919/http://cmkb.cellmigration.org/report.cgi?report=orth_overview&gene_id=3683">ITGAL</a> Info with links in the <a rel="nofollow" class="external text" href="http://www.cellmigration.org/index.shtml">Cell Migration Gateway</a> <a rel="nofollow" class="external text" href="https://web.archive.org/web/20141211173306/http://www.cellmigration.org/index.shtml">Archived</a> 2014-12-11 at the <a href="/wiki/Wayback_Machine" title="Wayback Machine">Wayback Machine</a></li> <li>Human <a rel="nofollow" class="external text" href="https://genome.ucsc.edu/cgi-bin/hgTracks?db=hg38&singleSearch=knownCanonical&position=ITGAL"><i>ITGAL</i></a> genome location and <a rel="nofollow" class="external text" href="https://genome.ucsc.edu/cgi-bin/hgGene?db=hg38&hgg_type=knownGene&hgg_gene=ITGAL"><i>ITGAL</i></a> gene details page in the <a href="/wiki/UCSC_Genome_Browser" title="UCSC Genome Browser">UCSC Genome Browser</a>.</li></ul> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox" aria-labelledby="Proteins:_clusters_of_differentiation_(see_also_list_of_human_clusters_of_differentiation)188" style="padding:3px"><table class="nowraplinks mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="background:#e7dcc3"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Clusters_of_differentiation" title="Template:Clusters of differentiation"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Clusters_of_differentiation" title="Template talk:Clusters of differentiation"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Clusters_of_differentiation" title="Special:EditPage/Template:Clusters of differentiation"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Proteins:_clusters_of_differentiation_(see_also_list_of_human_clusters_of_differentiation)188" style="font-size:114%;margin:0 4em"><a href="/wiki/Protein" title="Protein">Proteins</a>: <a href="/wiki/Cluster_of_differentiation" title="Cluster of differentiation">clusters of differentiation</a> (see also <a href="/wiki/List_of_human_clusters_of_differentiation" title="List of human clusters of differentiation">list of human clusters of differentiation</a>)</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">1–50</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CD1" title="CD1">CD1</a> <ul><li><a href="/wiki/Group_1_CD1" class="mw-redirect" title="Group 1 CD1">a-c</a></li> <li><a href="/wiki/CD1A" title="CD1A">1A</a></li> <li><a href="/wiki/CD1b" title="CD1b">1B</a></li> <li><a href="/wiki/CD1D" title="CD1D">1D</a></li> <li><a href="/wiki/CD1E" title="CD1E">1E</a></li></ul></li> <li><a href="/wiki/CD2" title="CD2">CD2</a></li> <li><a href="/wiki/CD3_(immunology)" title="CD3 (immunology)">CD3</a> <ul><li><a href="/wiki/CD3G" title="CD3G">γ</a></li> <li><a href="/wiki/CD3D" title="CD3D">δ</a></li> <li><a href="/wiki/CD3E" class="mw-redirect" title="CD3E">ε</a></li></ul></li> <li><a href="/wiki/CD4" title="CD4">CD4</a></li> <li><a href="/wiki/CD5_(protein)" title="CD5 (protein)">CD5</a></li> <li><a href="/wiki/CD6" title="CD6">CD6</a></li> <li><a href="/wiki/CD7" title="CD7">CD7</a></li> <li><a href="/wiki/CD8" title="CD8">CD8</a> <ul><li><a href="/wiki/CD8A" title="CD8A">a</a></li></ul></li> <li><a href="/wiki/CD9" title="CD9">CD9</a></li> <li><a href="/wiki/Neprilysin" title="Neprilysin">CD10</a></li> <li><i>CD11</i> <ul><li><a href="/wiki/CD11a" class="mw-redirect" title="CD11a">a</a></li> <li><a href="/wiki/Integrin_alpha_M" title="Integrin alpha M">b</a></li> <li><a href="/wiki/CD11c" class="mw-redirect" title="CD11c">c</a></li> <li><a href="/wiki/ITGAD" class="mw-redirect" title="ITGAD">d</a></li></ul></li> <li><a href="/wiki/Alanine_aminopeptidase" title="Alanine aminopeptidase">CD13</a></li> <li><a href="/wiki/CD14" title="CD14">CD14</a></li> <li><a href="/wiki/CD15" class="mw-redirect" title="CD15">CD15</a></li> <li><a href="/wiki/CD16" title="CD16">CD16</a> <ul><li><a href="/wiki/FCGR3A" title="FCGR3A">A</a></li> <li><a href="/wiki/FCGR3B" title="FCGR3B">B</a></li></ul></li> <li><a href="/wiki/CD18" class="mw-redirect" title="CD18">CD18</a></li> <li><a href="/wiki/CD19" title="CD19">CD19</a></li> <li><a href="/wiki/CD20" title="CD20">CD20</a></li> <li><a href="/wiki/Complement_receptor_2" title="Complement receptor 2">CD21</a></li> <li><a href="/wiki/CD22" title="CD22">CD22</a></li> <li><a href="/wiki/CD23" title="CD23">CD23</a></li> <li><a href="/wiki/CD24" title="CD24">CD24</a></li> <li><a href="/wiki/IL2RA" title="IL2RA">CD25</a></li> <li><a href="/wiki/Dipeptidyl_peptidase-4" title="Dipeptidyl peptidase-4">CD26</a></li> <li><a href="/wiki/CD27" title="CD27">CD27</a></li> <li><a href="/wiki/CD28" title="CD28">CD28</a></li> <li><a href="/wiki/Integrin_beta_1" title="Integrin beta 1">CD29</a></li> <li><a href="/wiki/CD30" title="CD30">CD30</a></li> <li><a href="/wiki/CD31" title="CD31">CD31</a></li> <li><a href="/wiki/CD32" title="CD32">CD32</a> <ul><li><a href="/wiki/FCGR2A" title="FCGR2A">A</a></li> <li><a href="/wiki/FCGR2B" title="FCGR2B">B</a></li></ul></li> <li><a href="/wiki/CD33" title="CD33">CD33</a></li> <li><a href="/wiki/CD34" title="CD34">CD34</a></li> <li><a href="/wiki/Complement_receptor_1" title="Complement receptor 1">CD35</a></li> <li><a href="/wiki/CD36" title="CD36">CD36</a></li> <li><a href="/wiki/CD37" title="CD37">CD37</a></li> <li><a href="/wiki/CD38" title="CD38">CD38</a></li> <li><a href="/wiki/ENTPD1" title="ENTPD1">CD39</a></li> <li><a href="/wiki/CD40_(protein)" title="CD40 (protein)">CD40</a></li> <li><a href="/wiki/ITGA2B" class="mw-redirect" title="ITGA2B">CD41</a></li> <li><a href="/wiki/Glycoprotein_Ib" title="Glycoprotein Ib">CD42</a> <ul><li><a href="/wiki/Glycoprotein_IX" title="Glycoprotein IX">a</a></li> <li><a href="/wiki/GP1BA" title="GP1BA">b</a></li> <li><a href="/wiki/GP1BB" title="GP1BB">c</a></li> <li><a href="/wiki/GP5_(gene)" title="GP5 (gene)">d</a></li></ul></li> <li><a href="/wiki/CD43" title="CD43">CD43</a></li> <li><a href="/wiki/CD44" title="CD44">CD44</a></li> <li><a href="/wiki/PTPRC" title="PTPRC">CD45</a></li> <li><a href="/wiki/CD46" title="CD46">CD46</a></li> <li><a href="/wiki/CD47" title="CD47">CD47</a></li> <li><a href="/wiki/CD48" title="CD48">CD48</a></li> <li><i>CD49</i> <ul><li><a href="/wiki/CD49a" class="mw-redirect" title="CD49a">a</a></li> <li><a href="/wiki/CD49b" class="mw-redirect" title="CD49b">b</a></li> <li><a href="/wiki/CD49c" class="mw-redirect" title="CD49c">c</a></li> <li><a href="/wiki/CD49d" class="mw-redirect" title="CD49d">d</a></li> <li><a href="/wiki/ITGA5" class="mw-redirect" title="ITGA5">e</a></li> <li><a href="/wiki/ITGA6" class="mw-redirect" title="ITGA6">f</a></li></ul></li> <li><a href="/wiki/ICAM3" title="ICAM3">CD50</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">51–100</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/ITGAV" class="mw-redirect" title="ITGAV">CD51</a></li> <li><a href="/wiki/CD52" title="CD52">CD52</a></li> <li><a href="/wiki/CD53" title="CD53">CD53</a></li> <li><a href="/wiki/ICAM-1" title="ICAM-1">CD54</a></li> <li><a href="/wiki/Decay-accelerating_factor" title="Decay-accelerating factor">CD55</a></li> <li><a href="/wiki/Neural_cell_adhesion_molecule" title="Neural cell adhesion molecule">CD56</a></li> <li><a href="/wiki/B3GAT1" title="B3GAT1">CD57</a></li> <li><a href="/wiki/CD58" title="CD58">CD58</a></li> <li><a href="/wiki/CD59" title="CD59">CD59</a></li> <li><a href="/wiki/CD61" class="mw-redirect" title="CD61">CD61</a></li> <li><a href="/wiki/Selectin" title="Selectin">CD62</a> <ul><li><a href="/wiki/E-selectin" title="E-selectin">E</a></li> <li><a href="/wiki/L-selectin" title="L-selectin">L</a></li> <li><a href="/wiki/P-selectin" title="P-selectin">P</a></li></ul></li> <li><a href="/wiki/CD63" title="CD63">CD63</a></li> <li><a href="/wiki/CD64_(biology)" title="CD64 (biology)">CD64</a> <ul><li><a href="/wiki/FCGR1A" title="FCGR1A">A</a></li> <li><a href="/wiki/FCGR1B" class="mw-redirect" title="FCGR1B">B</a></li> <li><a href="/wiki/FCGR1C" class="mw-redirect" title="FCGR1C">C</a></li></ul></li> <li><a href="/wiki/Carcinoembryonic_antigen" title="Carcinoembryonic antigen">CD66</a> <ul><li><a href="/wiki/CEACAM1" title="CEACAM1">a</a></li> <li><a href="/wiki/CEACAM8" title="CEACAM8">b</a></li> <li><a href="/wiki/CEACAM6" title="CEACAM6">c</a></li> <li><a href="/wiki/CEACAM3" title="CEACAM3">d</a></li> <li><a href="/wiki/CEACAM5" title="CEACAM5">e</a></li> <li><a href="/wiki/PSG1_(gene)" class="mw-redirect" title="PSG1 (gene)">f</a></li></ul></li> <li><a href="/wiki/CD68" title="CD68">CD68</a></li> <li><a href="/wiki/CD69" title="CD69">CD69</a></li> <li><a href="/wiki/CD70" title="CD70">CD70</a></li> <li><a href="/wiki/TFRC" class="mw-redirect" title="TFRC">CD71</a></li> <li><a href="/wiki/CD72" title="CD72">CD72</a></li> <li><a href="/wiki/NT5E" title="NT5E">CD73</a></li> <li><a href="/wiki/CD74" title="CD74">CD74</a></li> <li><a href="/wiki/CD78" title="CD78">CD78</a></li> <li><a href="/wiki/CD79" title="CD79">CD79</a> <ul><li><a href="/wiki/CD79A" title="CD79A">a</a></li> <li><a href="/wiki/CD79B" title="CD79B">b</a></li></ul></li> <li><a href="/wiki/CD80" title="CD80">CD80</a></li> <li><a href="/wiki/CD81" title="CD81">CD81</a></li> <li><a href="/wiki/CD82_(gene)" title="CD82 (gene)">CD82</a></li> <li><a href="/wiki/CD83" title="CD83">CD83</a></li> <li><a href="/wiki/CD84" title="CD84">CD84</a></li> <li><i>CD85</i> <ul><li><a href="/wiki/LILRB3" title="LILRB3">a</a></li> <li><a href="/wiki/LILRB2" title="LILRB2">d</a></li> <li><a href="/wiki/LILRA3" title="LILRA3">e</a></li> <li><a href="/wiki/LILRA2" title="LILRA2">h</a></li> <li><a href="/wiki/LILRB1" title="LILRB1">j</a></li> <li><a href="/wiki/LILRB4" title="LILRB4">k</a></li></ul></li> <li><a href="/wiki/CD86" title="CD86">CD86</a></li> <li><a href="/wiki/Urokinase_receptor" title="Urokinase receptor">CD87</a></li> <li><a href="/wiki/C5a_receptor" title="C5a receptor">CD88</a></li> <li><a href="/wiki/FCAR" title="FCAR">CD89</a></li> <li><a href="/wiki/CD90" title="CD90">CD90</a></li> <li><a href="/wiki/LRP1" title="LRP1">CD91</a> - <a href="/wiki/SLC44A1" class="mw-redirect" title="SLC44A1">CD92</a></li> <li><a href="/wiki/CD93" title="CD93">CD93</a></li> <li><a href="/wiki/KLRD1" title="KLRD1">CD94</a></li> <li><a href="/wiki/Fas_receptor" title="Fas receptor">CD95</a></li> <li><a href="/wiki/CD96" title="CD96">CD96</a></li> <li><a href="/wiki/CD97" title="CD97">CD97</a></li> <li><a href="/wiki/CD98" title="CD98">CD98</a></li> <li><a href="/wiki/CD99" title="CD99">CD99</a></li> <li><a href="/wiki/SEMA4D" title="SEMA4D">CD100</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">101–150</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/IGSF2" title="IGSF2">CD101</a></li> <li><a href="/wiki/ICAM2" title="ICAM2">CD102</a></li> <li><a href="/wiki/ITGAE" title="ITGAE">CD103</a></li> <li><a href="/wiki/ITGB4" class="mw-redirect" title="ITGB4">CD104</a></li> <li><a href="/wiki/Endoglin" title="Endoglin">CD105</a></li> <li><a href="/wiki/VCAM-1" title="VCAM-1">CD106</a></li> <li><i>CD107</i> <ul><li><a href="/wiki/LAMP1" title="LAMP1">a</a></li> <li><a href="/wiki/LAMP2" title="LAMP2">b</a></li></ul></li> <li><a href="/wiki/SEMA7A" title="SEMA7A">CD108</a></li> <li><a href="/wiki/CD109" title="CD109">CD109</a></li> <li><a href="/wiki/Myeloproliferative_leukemia_virus_oncogene" class="mw-redirect" title="Myeloproliferative leukemia virus oncogene">CD110</a></li> <li><a href="/wiki/PVRL1" class="mw-redirect" title="PVRL1">CD111</a></li> <li><a href="/wiki/PVRL2" class="mw-redirect" title="PVRL2">CD112</a></li> <li><a href="/wiki/PVRL3" class="mw-redirect" title="PVRL3">CD113</a></li> <li><a href="/wiki/Granulocyte_colony-stimulating_factor_receptor" title="Granulocyte colony-stimulating factor receptor">CD114</a></li> <li><a href="/wiki/Colony_stimulating_factor_1_receptor" title="Colony stimulating factor 1 receptor">CD115</a></li> <li><a href="/wiki/Granulocyte_macrophage_colony-stimulating_factor_receptor" class="mw-redirect" title="Granulocyte macrophage colony-stimulating factor receptor">CD116</a></li> <li><a href="/wiki/KIT_(gene)" title="KIT (gene)">CD117</a></li> <li><a href="/wiki/Leukemia_inhibitory_factor_receptor" title="Leukemia inhibitory factor receptor">CD118</a></li> <li><a href="/wiki/Interferon_gamma_receptor_1" title="Interferon gamma receptor 1">CD119</a></li> <li><a href="/wiki/CD120" title="CD120">CD120</a> <ul><li><a href="/wiki/TNFRSF1A" class="mw-redirect" title="TNFRSF1A">a</a></li> <li><a href="/wiki/TNFRSF1B" class="mw-redirect" title="TNFRSF1B">b</a></li></ul></li> <li><i>CD121</i> <ul><li><a href="/wiki/Interleukin_1_receptor,_type_I" title="Interleukin 1 receptor, type I">a</a></li> <li><a href="/wiki/Interleukin_1_receptor,_type_II" title="Interleukin 1 receptor, type II">b</a></li></ul></li> <li><a href="/wiki/IL2RB" title="IL2RB">CD122</a></li> <li><a href="/wiki/IL3RA" title="IL3RA">CD123</a></li> <li><a href="/wiki/Interleukin-4_receptor" title="Interleukin-4 receptor">CD124</a></li> <li><a href="/wiki/Interleukin_5_receptor_alpha_subunit" title="Interleukin 5 receptor alpha subunit">CD125</a></li> <li><a href="/wiki/Interleukin-6_receptor" title="Interleukin-6 receptor">CD126</a></li> <li><a href="/wiki/Interleukin-7_receptor" title="Interleukin-7 receptor">CD127</a></li> <li><a href="/wiki/Interleukin-9_receptor" title="Interleukin-9 receptor">CD129</a></li> <li><a href="/wiki/Glycoprotein_130" title="Glycoprotein 130">CD130</a></li> <li><a href="/wiki/CSF2RB" title="CSF2RB">CD131</a></li> <li><a href="/wiki/Common_gamma_chain" title="Common gamma chain">CD132</a></li> <li><a href="/wiki/CD133" title="CD133">CD133</a></li> <li><a href="/wiki/CD134" title="CD134">CD134</a></li> <li><a href="/wiki/CD135" title="CD135">CD135</a></li> <li><a href="/wiki/MST1R" title="MST1R">CD136</a></li> <li><a href="/wiki/CD137" title="CD137">CD137</a></li> <li><a href="/wiki/Syndecan_1" title="Syndecan 1">CD138</a></li> <li><a href="/wiki/PDGFRB" title="PDGFRB">CD140b</a></li> <li><a href="/wiki/Thrombomodulin" title="Thrombomodulin">CD141</a></li> <li><a href="/wiki/Tissue_factor" title="Tissue factor">CD142</a></li> <li><a href="/wiki/Angiotensin-converting_enzyme" title="Angiotensin-converting enzyme">CD143</a></li> <li><a href="/wiki/VE-cadherin" title="VE-cadherin">CD144</a></li> <li><a href="/wiki/CD146" title="CD146">CD146</a></li> <li><a href="/wiki/Basigin" title="Basigin">CD147</a></li> <li><a href="/wiki/PTPRJ" title="PTPRJ">CD148</a></li> <li><a href="/wiki/SLAMF1" title="SLAMF1">CD150</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">151–200</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CD151" title="CD151">CD151</a></li> <li><a href="/wiki/CTLA-4" class="mw-redirect" title="CTLA-4">CD152</a></li> <li><a href="/wiki/CD153" title="CD153">CD153</a></li> <li><a href="/wiki/CD154" title="CD154">CD154</a></li> <li><a href="/wiki/CD155" title="CD155">CD155</a></li> <li><i>CD156</i> <ul><li><a href="/wiki/ADAM8" title="ADAM8">a</a></li> <li><a href="/wiki/ADAM17" title="ADAM17">b</a></li> <li><a href="/wiki/ADAM10" title="ADAM10">c</a></li></ul></li> <li><a href="/wiki/BST1" title="BST1">CD157</a></li> <li><i>CD158</i> (<a href="/wiki/KIR2DL1" title="KIR2DL1">a</a></li> <li><a href="/wiki/KIR2DL4" title="KIR2DL4">d</a></li> <li><a href="/wiki/KIR3DL1" title="KIR3DL1">e</a></li> <li><a href="/wiki/KIR2DS4" title="KIR2DS4">i</a></li> <li><a href="/wiki/KIR3DL2" title="KIR3DL2">k</a>)</li> <li><i>CD159</i> <ul><li><a href="/wiki/NKG2" title="NKG2">a</a></li> <li><a href="/wiki/KLRC2" title="KLRC2">c</a></li></ul></li> <li><a href="/wiki/CD160" title="CD160">CD160</a></li> <li><a href="/wiki/KLRB1" title="KLRB1">CD161</a></li> <li><a href="/wiki/P-selectin_glycoprotein_ligand-1" title="P-selectin glycoprotein ligand-1">CD162</a></li> <li><a href="/wiki/CD163" title="CD163">CD163</a></li> <li><a href="/wiki/CD164" title="CD164">CD164</a></li> <li><a href="/wiki/ALCAM" title="ALCAM">CD166</a></li> <li><i>CD167</i> <ul><li><a href="/wiki/DDR1" title="DDR1">a</a></li> <li><a href="/wiki/Discoidin_domain-containing_receptor_2" title="Discoidin domain-containing receptor 2">b</a></li></ul></li> <li><a href="/wiki/Hyaluronan-mediated_motility_receptor" title="Hyaluronan-mediated motility receptor">CD168</a></li> <li><a href="/wiki/Sialoadhesin" title="Sialoadhesin">CD169</a></li> <li><a href="/wiki/SIGLEC5" title="SIGLEC5">CD170</a></li> <li><a href="/wiki/L1_(protein)" title="L1 (protein)">CD171</a></li> <li><i>CD172</i> <ul><li><a href="/wiki/Signal-regulatory_protein_alpha" title="Signal-regulatory protein alpha">a</a></li> <li><a href="/wiki/SIRPB1" title="SIRPB1">b</a></li> <li><a href="/wiki/SIRPG" title="SIRPG">g</a></li></ul></li> <li><a href="/wiki/Fucosyltransferase_3" title="Fucosyltransferase 3">CD174</a></li> <li><a href="/wiki/CD177" title="CD177">CD177</a></li> <li><a href="/wiki/Fas_ligand" title="Fas ligand">CD178</a></li> <li><i>CD179</i> <ul><li><a href="/wiki/VPREB1" title="VPREB1">a</a></li> <li><a href="/wiki/IGLL1" title="IGLL1">b</a></li></ul></li> <li><a href="/wiki/CD180" title="CD180">CD180</a></li> <li><a href="/wiki/Interleukin_8_receptor,_alpha" title="Interleukin 8 receptor, alpha">CD181</a></li> <li><a href="/wiki/Interleukin_8_receptor,_beta" title="Interleukin 8 receptor, beta">CD182</a></li> <li><a href="/wiki/CXCR3" title="CXCR3">CD183</a></li> <li><a href="/wiki/CXCR4" title="CXCR4">CD184</a></li> <li><a href="/wiki/CXCR5" title="CXCR5">CD185</a></li> <li><a href="/wiki/CXCR6" title="CXCR6">CD186</a></li> <li><a href="/wiki/CCR1" title="CCR1">CD191</a></li> <li><a href="/wiki/CCR2" title="CCR2">CD192</a></li> <li><a href="/wiki/CCR3_(gene)" title="CCR3 (gene)">CD193</a></li> <li><a href="/wiki/CCR4" title="CCR4">CD194</a></li> <li><a href="/wiki/CCR5" title="CCR5">CD195</a></li> <li><a href="/wiki/C-C_chemokine_receptor_type_6" title="C-C chemokine receptor type 6">CD196</a></li> <li><a href="/wiki/C-C_chemokine_receptor_type_7" title="C-C chemokine receptor type 7">CD197</a></li> <li><a href="/wiki/CCR8_(gene)" title="CCR8 (gene)">CDw198</a></li> <li><a href="/wiki/CCR9" title="CCR9">CDw199</a></li> <li><a href="/wiki/CD200" title="CD200">CD200</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">201–250</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Endothelial_protein_C_receptor" title="Endothelial protein C receptor">CD201</a></li> <li><a href="/wiki/TEK_tyrosine_kinase" title="TEK tyrosine kinase">CD202b</a></li> <li><a href="/wiki/MSR1" title="MSR1">CD204</a></li> <li><a href="/wiki/LY75" class="mw-redirect" title="LY75">CD205</a></li> <li><a href="/wiki/Mannose_receptor" title="Mannose receptor">CD206</a></li> <li><a href="/wiki/CD207" class="mw-redirect" title="CD207">CD207</a></li> <li><a href="/wiki/LAMP3" title="LAMP3">CD208</a></li> <li><a href="/wiki/DC-SIGN" title="DC-SIGN">CD209</a></li> <li><i>CDw210</i> <ul><li><a href="/wiki/Interleukin_10_receptor,_alpha_subunit" title="Interleukin 10 receptor, alpha subunit">a</a></li> <li><a href="/wiki/Interleukin_10_receptor,_beta_subunit" title="Interleukin 10 receptor, beta subunit">b</a></li></ul></li> <li><a href="/wiki/Interleukin_12_receptor,_beta_1_subunit" title="Interleukin 12 receptor, beta 1 subunit">CD212</a></li> <li><i>CD213a</i> <ul><li><a href="/wiki/IL13RA1" class="mw-redirect" title="IL13RA1">1</a></li> <li><a href="/wiki/IL13RA2" title="IL13RA2">2</a></li></ul></li> <li><a href="/wiki/IL17RA" title="IL17RA">CD217</a></li> <li><i>CD218</i> (<a href="/wiki/IL18R1" title="IL18R1">a</a></li> <li><a href="/wiki/IL18RAP" title="IL18RAP">b</a>)</li> <li><a href="/wiki/Insulin_receptor" title="Insulin receptor">CD220</a></li> <li><a href="/wiki/Insulin-like_growth_factor_1_receptor" title="Insulin-like growth factor 1 receptor">CD221</a></li> <li><a href="/wiki/Insulin-like_growth_factor_2_receptor" title="Insulin-like growth factor 2 receptor">CD222</a></li> <li><a href="/wiki/LAG3" class="mw-redirect" title="LAG3">CD223</a></li> <li><a href="/wiki/GGT1" class="mw-redirect" title="GGT1">CD224</a></li> <li><a href="/wiki/IFITM1" title="IFITM1">CD225</a></li> <li><a href="/wiki/CD226" title="CD226">CD226</a></li> <li><a href="/wiki/MUC1" class="mw-redirect" title="MUC1">CD227</a></li> <li><a href="/wiki/MFI2" class="mw-redirect" title="MFI2">CD228</a></li> <li><a href="/wiki/LY9" title="LY9">CD229</a></li> <li><a href="/wiki/PRNP" class="mw-redirect" title="PRNP">CD230</a></li> <li><a href="/wiki/Band_3" class="mw-redirect" title="Band 3">CD233</a></li> <li><a href="/wiki/Duffy_antigen_system" title="Duffy antigen system">CD234</a></li> <li><i>CD235</i> <ul><li><a href="/wiki/GYPA" class="mw-redirect" title="GYPA">a</a></li> <li><a href="/wiki/GYPB" title="GYPB">b</a></li></ul></li> <li><a href="/wiki/Glycophorin_C" title="Glycophorin C">CD236</a></li> <li><a href="/wiki/Kell_antigen_system" title="Kell antigen system">CD238</a></li> <li><a href="/wiki/Basal_cell_adhesion_molecule" title="Basal cell adhesion molecule">CD239</a></li> <li><a href="/wiki/RHCE_(gene)" title="RHCE (gene)">CD240CE</a></li> <li><a href="/wiki/RHD_(gene)" title="RHD (gene)">CD240D</a></li> <li><a href="/wiki/RHAG" title="RHAG">CD241</a></li> <li><a href="/wiki/P-glycoprotein" title="P-glycoprotein">CD243</a></li> <li><a href="/wiki/CD244" title="CD244">CD244</a></li> <li><a href="/wiki/Anaplastic_lymphoma_kinase" title="Anaplastic lymphoma kinase">CD246</a></li> <li><a href="/wiki/CD247" class="mw-redirect" title="CD247">CD247</a> - <a href="/wiki/CD248" title="CD248">CD248</a></li> <li><a href="/wiki/Glutamyl_aminopeptidase" title="Glutamyl aminopeptidase">CD249</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">251–300</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/OX40L" class="mw-redirect" title="OX40L"> CD252</a></li> <li><a href="/wiki/TRAIL" title="TRAIL">CD253</a></li> <li><a href="/wiki/RANKL" title="RANKL">CD254</a></li> <li><a href="/wiki/TNFSF13" class="mw-redirect" title="TNFSF13">CD256</a></li> <li><a href="/wiki/B-cell_activating_factor" title="B-cell activating factor">CD257</a></li> <li><a href="/wiki/TNFSF14" class="mw-redirect" title="TNFSF14">CD258</a></li> <li><a href="/wiki/TNFRSF10A" class="mw-redirect" title="TNFRSF10A">CD261</a></li> <li><a href="/wiki/TNFRSF10B" class="mw-redirect" title="TNFRSF10B">CD262</a></li> <li><a href="/wiki/TNFRSF10C" class="mw-redirect" title="TNFRSF10C">CD263</a></li> <li><a href="/wiki/TNFRSF10D" class="mw-redirect" title="TNFRSF10D">CD264</a></li> <li><a href="/wiki/RANK" title="RANK">CD265</a></li> <li><a href="/wiki/TNFRSF12A" title="TNFRSF12A">CD266</a></li> <li><a href="/wiki/TNFRSF13B" class="mw-redirect" title="TNFRSF13B">CD267</a></li> <li><a href="/wiki/TNFRSF13C" class="mw-redirect" title="TNFRSF13C">CD268</a></li> <li><a href="/wiki/TNFRSF17" class="mw-redirect" title="TNFRSF17">CD269</a></li> <li><a href="/wiki/Low-affinity_nerve_growth_factor_receptor" title="Low-affinity nerve growth factor receptor">CD271</a></li> <li><a href="/wiki/BTLA" title="BTLA">CD272</a></li> <li><a href="/wiki/PDCD1LG2" title="PDCD1LG2">CD273</a></li> <li><a href="/wiki/CD274" class="mw-redirect" title="CD274">CD274</a></li> <li><a href="/wiki/ICOSLG" title="ICOSLG">CD275</a></li> <li><a href="/wiki/CD276" title="CD276">CD276</a></li> <li><a href="/wiki/CD278" title="CD278">CD278</a></li> <li><a href="/wiki/Programmed_cell_death_protein_1" title="Programmed cell death protein 1">CD279</a></li> <li><a href="/wiki/Mannose_receptor" title="Mannose receptor">CD280</a></li> <li><a href="/wiki/TLR_1" class="mw-redirect" title="TLR 1">CD281</a></li> <li><a href="/wiki/TLR2" class="mw-redirect" title="TLR2">CD282</a></li> <li><a href="/wiki/TLR3" class="mw-redirect" title="TLR3">CD283</a></li> <li><a href="/wiki/TLR4" class="mw-redirect" title="TLR4">CD284</a></li> <li><a href="/wiki/TLR6" class="mw-redirect" title="TLR6">CD286</a></li> <li><a href="/wiki/TLR8" class="mw-redirect" title="TLR8">CD288</a></li> <li><a href="/wiki/TLR9" class="mw-redirect" title="TLR9">CD289</a></li> <li><a href="/wiki/TLR10" class="mw-redirect" title="TLR10">CD290</a></li> <li><a href="/wiki/BMPR1A" title="BMPR1A">CD292</a></li> <li><a href="/wiki/BMPR1B" title="BMPR1B">CDw293</a></li> <li><a href="/wiki/CD294" class="mw-redirect" title="CD294">CD294</a></li> <li><a href="/wiki/Leptin_receptor" title="Leptin receptor">CD295</a></li> <li><a href="/wiki/ART4" title="ART4">CD297</a></li> <li><a href="/wiki/ATP1B3" title="ATP1B3">CD298</a></li> <li><a href="/wiki/CLEC4M" title="CLEC4M">CD299</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">301–350</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CD300A" title="CD300A">CD300A</a></li> <li><a href="/wiki/CLEC10A" title="CLEC10A">CD301</a></li> <li><a href="/wiki/CD302" title="CD302">CD302</a></li> <li><a href="/wiki/CLEC4C" title="CLEC4C">CD303</a></li> <li><a href="/wiki/Neuropilin" title="Neuropilin">CD304</a></li> <li><a href="/wiki/LAIR1" title="LAIR1">CD305</a></li> <li><a href="/wiki/LAIR2" title="LAIR2">CD306</a></li> <li><a href="/wiki/FCRL5" title="FCRL5">CD307</a></li> <li><a href="/wiki/Kinase_insert_domain_receptor" title="Kinase insert domain receptor">CD309</a></li> <li><a href="/wiki/EMR2" title="EMR2">CD312</a></li> <li><a href="/wiki/NKG2D" title="NKG2D">CD314</a></li> <li><a href="/wiki/PTGFRN" title="PTGFRN">CD315</a></li> <li><a href="/wiki/IGSF8" title="IGSF8">CD316</a></li> <li><a href="/wiki/Tetherin" title="Tetherin">CD317</a></li> <li><a href="/wiki/CDCP1" title="CDCP1">CD318</a></li> <li><a href="/wiki/CD320" title="CD320">CD320</a></li> <li><a href="/wiki/F11_receptor" title="F11 receptor">CD321</a></li> <li><a href="/wiki/JAM2" title="JAM2">CD322</a></li> <li><a href="/wiki/CDH1_(gene)" class="mw-redirect" title="CDH1 (gene)">CD324</a></li> <li><a href="/wiki/CDH2" class="mw-redirect" title="CDH2">CD325</a></li> <li><a href="/wiki/Epithelial_cell_adhesion_molecule" title="Epithelial cell adhesion molecule">CD326</a></li> <li><a href="/wiki/SIGLEC6" title="SIGLEC6">CD327</a></li> <li><a href="/wiki/SIGLEC7" title="SIGLEC7">CD328</a></li> <li><a href="/wiki/SIGLEC9" title="SIGLEC9">CD329</a></li> <li><a href="/wiki/Fibroblast_growth_factor_receptor_1" title="Fibroblast growth factor receptor 1">CD331</a></li> <li><a href="/wiki/Fibroblast_growth_factor_receptor_2" title="Fibroblast growth factor receptor 2">CD332</a></li> <li><a href="/wiki/Fibroblast_growth_factor_receptor_3" title="Fibroblast growth factor receptor 3">CD333</a></li> <li><a href="/wiki/Fibroblast_growth_factor_receptor_4" title="Fibroblast growth factor receptor 4">CD334</a></li> <li><a href="/wiki/NCR1" title="NCR1">CD335</a></li> <li><a href="/wiki/NCR2" title="NCR2">CD336</a></li> <li><a href="/wiki/NCR3" title="NCR3">CD337</a></li> <li><a href="/wiki/ABCG2" title="ABCG2">CD338</a></li> <li><a href="/wiki/JAG1" title="JAG1">CD339</a></li> <li><a href="/wiki/HER2/neu" class="mw-redirect" title="HER2/neu">CD340</a></li> <li><a href="/wiki/FZD4" class="mw-redirect" title="FZD4">CD344</a></li> <li><a href="/wiki/FZD9" class="mw-redirect" title="FZD9">CD349</a></li> <li><a href="/wiki/FZD10" class="mw-redirect" title="FZD10">CD350</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox" aria-labelledby="Integrins123" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="background:#e7dcc3"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Integrins" title="Template:Integrins"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Integrins" title="Template talk:Integrins"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Integrins" title="Special:EditPage/Template:Integrins"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Integrins123" style="font-size:114%;margin:0 4em"><a href="/wiki/Integrin" title="Integrin">Integrins</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Alpha</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CD49a" class="mw-redirect" title="CD49a">A1</a></li> <li><a href="/wiki/CD49b" class="mw-redirect" title="CD49b">A2</a></li> <li><a href="/wiki/CD49c" class="mw-redirect" title="CD49c">A3</a></li> <li><a href="/wiki/CD49d" class="mw-redirect" title="CD49d">A4</a></li> <li><a href="/wiki/CD49e" class="mw-redirect" title="CD49e">A5</a></li> <li><a href="/wiki/ITGA6" class="mw-redirect" title="ITGA6">A6</a></li> <li><a href="/wiki/ITGA7" class="mw-redirect" title="ITGA7">A7</a></li> <li><a href="/wiki/ITGA8" class="mw-redirect" title="ITGA8">A8</a></li> <li><a href="/wiki/ITGA9" class="mw-redirect" title="ITGA9">A9</a></li> <li><a href="/wiki/ITGA10" class="mw-redirect" title="ITGA10">A10</a></li> <li><a href="/wiki/ITGA11" class="mw-redirect" title="ITGA11">A11</a></li> <li><a href="/wiki/ITGAD" class="mw-redirect" title="ITGAD">AD</a></li> <li><a href="/wiki/ITGAE" title="ITGAE">AE</a></li> <li><a href="/wiki/CD11a" class="mw-redirect" title="CD11a">AL</a></li> <li><a href="/wiki/Integrin_alpha_M" title="Integrin alpha M">AM</a></li> <li><a href="/wiki/ITGAV" class="mw-redirect" title="ITGAV">AV</a></li> <li><a href="/wiki/CD11c" class="mw-redirect" title="CD11c">AX</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Beta</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CD29" class="mw-redirect" title="CD29">B1</a></li> <li><a href="/wiki/CD18" class="mw-redirect" title="CD18">B2</a></li> <li><a href="/wiki/CD61" class="mw-redirect" title="CD61">B3</a></li> <li><a href="/wiki/ITGB4" class="mw-redirect" title="ITGB4">B4</a></li> <li><a href="/wiki/Integrin,_beta_5" class="mw-redirect" title="Integrin, beta 5">B5</a></li> <li><a href="/wiki/Integrin,_beta_6" class="mw-redirect" title="Integrin, beta 6">B6</a></li> <li><a href="/wiki/ITGB7" class="mw-redirect" title="ITGB7">B7</a></li> <li><a href="/wiki/ITGB8" class="mw-redirect" title="ITGB8">B8</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Dimers</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Cytoadhesin receptor:</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Integrin_alpha6beta4&action=edit&redlink=1" class="new" title="Integrin alpha6beta4 (page does not exist)">Integrin alpha6beta4</a></li> <li><a href="/wiki/Glycoprotein_IIb/IIIa" title="Glycoprotein IIb/IIIa">Glycoprotein IIb/IIIa</a> <ul><li><a href="/wiki/ITGA2B" class="mw-redirect" title="ITGA2B">ITGA2B</a>+<a href="/wiki/CD61" class="mw-redirect" title="CD61">ITGB3</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Fibrinogen receptor:</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Macrophage-1_antigen" title="Macrophage-1 antigen">Macrophage-1 antigen</a> <ul><li><a href="/wiki/Integrin_alpha_M" title="Integrin alpha M">CD11b</a>+<a href="/wiki/CD18" class="mw-redirect" title="CD18">CD18</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Fibronectin receptor:</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Integrin_alpha2beta1&action=edit&redlink=1" class="new" title="Integrin alpha2beta1 (page does not exist)">Integrin alpha2beta1</a></li> <li><a href="/wiki/VLA-4" title="VLA-4">Integrin alpha4beta1</a></li> <li><a href="/w/index.php?title=Integrin_alpha5beta1&action=edit&redlink=1" class="new" title="Integrin alpha5beta1 (page does not exist)">Integrin alpha5beta1</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Leukocyte-adhesion receptor:</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Lymphocyte_function-associated_antigen_1" title="Lymphocyte function-associated antigen 1">LFA-1</a> <ul><li><a href="/wiki/CD11a" class="mw-redirect" title="CD11a">CD11a</a>+<a href="/wiki/CD18" class="mw-redirect" title="CD18">CD18</a></li></ul></li> <li><a href="/wiki/Macrophage-1_antigen" title="Macrophage-1 antigen">Macrophage-1 antigen</a> <ul><li><a href="/wiki/Integrin_alpha_M" title="Integrin alpha M">CD11b</a>+<a href="/wiki/CD18" class="mw-redirect" title="CD18">CD18</a></li></ul></li> <li><a href="/wiki/Integrin_alphaXbeta2" class="mw-redirect" title="Integrin alphaXbeta2">Integrin alphaXbeta2</a> <ul><li><a href="/wiki/CD11c" class="mw-redirect" title="CD11c">CD11c</a>+<a href="/wiki/CD18" class="mw-redirect" title="CD18">CD18</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Very late antigen receptor:</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Integrin_alpha1beta1&action=edit&redlink=1" class="new" title="Integrin alpha1beta1 (page does not exist)">Integrin alpha1beta1</a></li> <li><a href="/w/index.php?title=Integrin_alpha2beta1&action=edit&redlink=1" class="new" title="Integrin alpha2beta1 (page does not exist)">Integrin alpha2beta1</a></li> <li><a href="/w/index.php?title=Integrin_alpha3beta1&action=edit&redlink=1" class="new" title="Integrin alpha3beta1 (page does not exist)">Integrin alpha3beta1</a></li> <li><a href="/wiki/VLA-4" title="VLA-4">VLA-4</a> <ul><li><a href="/wiki/CD49d" class="mw-redirect" title="CD49d">CD49d</a>+<a href="/wiki/CD29" class="mw-redirect" title="CD29">CD29</a></li></ul></li> <li><a href="/wiki/Alpha-5_beta-1" title="Alpha-5 beta-1">Alpha-5 beta-1</a></li> <li><a href="/w/index.php?title=Integrin_alpha6beta1&action=edit&redlink=1" class="new" title="Integrin alpha6beta1 (page does not exist)">Integrin alpha6beta1</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Vitronectin receptor:</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Alpha-v_beta-3" title="Alpha-v beta-3">Alpha-v beta-3</a></li> <li><a href="/wiki/Alpha-v_beta-5" title="Alpha-v beta-5">Alpha-v beta-5</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background-color: AntiqueWhite"><div><i>see also <a href="/wiki/Template:Cell_surface_receptor_deficiencies" title="Template:Cell surface receptor deficiencies">cell surface receptor deficiencies</a></i></div></td></tr></tbody></table></div> <p><br /> </p> <style data-mw-deduplicate="TemplateStyles:r1271159938">.mw-parser-output .asbox{position:relative;overflow:hidden}.mw-parser-output .asbox table{background:transparent}.mw-parser-output .asbox p{margin:0}.mw-parser-output .asbox p+p{margin-top:0.25em}.mw-parser-output .asbox-body{font-style:italic}.mw-parser-output .asbox-note{font-size:smaller}.mw-parser-output .asbox .navbar{position:absolute;top:-0.75em;right:1em;display:none}.mw-parser-output :not(p):not(.asbox)+style+.asbox,.mw-parser-output :not(p):not(.asbox)+link+.asbox{margin-top:3em}</style><div role="note" class="metadata plainlinks asbox stub"><table role="presentation"><tbody><tr class="noresize"><td><span typeof="mw:File"><a href="/wiki/File:DNA_stub.png" class="mw-file-description"><img alt="Stub icon" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/61/DNA_stub.png/40px-DNA_stub.png" decoding="async" width="40" height="30" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/61/DNA_stub.png/59px-DNA_stub.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/61/DNA_stub.png/79px-DNA_stub.png 2x" data-file-width="816" data-file-height="621" /></a></span></td><td><p class="asbox-body">This article on a <a href="/wiki/Gene" title="Gene">gene</a> on human <a href="/wiki/Chromosome_16" title="Chromosome 16">chromosome 16</a> is a <a href="/wiki/Wikipedia:Stub" title="Wikipedia:Stub">stub</a>. You can help Wikipedia by <a class="external text" href="https://en.wikipedia.org/w/index.php?title=Integrin_alpha_L&action=edit">expanding it</a>.</p></td></tr></tbody></table><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Gene-16-stub" title="Template:Gene-16-stub"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Gene-16-stub" title="Template talk:Gene-16-stub"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Gene-16-stub" title="Special:EditPage/Template:Gene-16-stub"><abbr title="Edit this template">e</abbr></a></li></ul></div></div>    </div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?useformat=desktop&type=1x1&usesul3=0" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="">Retrieved from "<a dir="ltr" href="https://en.wikipedia.org/w/index.php?title=Integrin_alpha_L&oldid=1228262317">https://en.wikipedia.org/w/index.php?title=Integrin_alpha_L&oldid=1228262317</a>"</div></div> <div id="catlinks" class="catlinks" data-mw="interface"><div id="mw-normal-catlinks" class="mw-normal-catlinks"><a href="/wiki/Help:Category" title="Help:Category">Categories</a>: <ul><li><a href="/wiki/Category:Genes_on_human_chromosome_16" title="Category:Genes on human chromosome 16">Genes on human chromosome 16</a></li><li><a href="/wiki/Category:Integrins" title="Category:Integrins">Integrins</a></li><li><a href="/wiki/Category:Clusters_of_differentiation" title="Category:Clusters of differentiation">Clusters of differentiation</a></li><li><a href="/wiki/Category:Human_chromosome_16_gene_stubs" title="Category:Human chromosome 16 gene stubs">Human chromosome 16 gene stubs</a></li></ul></div><div id="mw-hidden-catlinks" class="mw-hidden-catlinks mw-hidden-cats-hidden">Hidden categories: <ul><li><a href="/wiki/Category:Articles_with_short_description" title="Category:Articles with short description">Articles with short description</a></li><li><a href="/wiki/Category:Short_description_matches_Wikidata" title="Category:Short description matches Wikidata">Short description matches Wikidata</a></li><li><a href="/wiki/Category:Webarchive_template_wayback_links" title="Category:Webarchive template wayback links">Webarchive template wayback links</a></li><li><a href="/wiki/Category:All_stub_articles" title="Category:All stub articles">All stub articles</a></li></ul></div></div> </div> </main> </div> <div class="mw-footer-container"> <footer id="footer" class="mw-footer" > <ul id="footer-info"> <li id="footer-info-lastmod"> This page was last edited on 10 June 2024, at 08:31<span class="anonymous-show"> (UTC)</span>.</li> <li id="footer-info-copyright">Text is available under the <a href="/wiki/Wikipedia:Text_of_the_Creative_Commons_Attribution-ShareAlike_4.0_International_License" title="Wikipedia:Text of the Creative Commons Attribution-ShareAlike 4.0 International License">Creative Commons Attribution-ShareAlike 4.0 License</a>; additional terms may apply. By using this site, you agree to the <a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Terms_of_Use" class="extiw" title="foundation:Special:MyLanguage/Policy:Terms of Use">Terms of Use</a> and <a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Privacy_policy" class="extiw" title="foundation:Special:MyLanguage/Policy:Privacy policy">Privacy Policy</a>. Wikipedia® is a registered trademark of the <a rel="nofollow" class="external text" href="https://wikimediafoundation.org/">Wikimedia Foundation, Inc.</a>, a non-profit organization.</li> </ul> <ul id="footer-places"> <li id="footer-places-privacy"><a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Privacy_policy">Privacy policy</a></li> <li id="footer-places-about"><a href="/wiki/Wikipedia:About">About Wikipedia</a></li> <li id="footer-places-disclaimers"><a href="/wiki/Wikipedia:General_disclaimer">Disclaimers</a></li> <li id="footer-places-contact"><a href="//en.wikipedia.org/wiki/Wikipedia:Contact_us">Contact Wikipedia</a></li> <li id="footer-places-wm-codeofconduct"><a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Universal_Code_of_Conduct">Code of Conduct</a></li> <li id="footer-places-developers"><a href="https://developer.wikimedia.org">Developers</a></li> <li id="footer-places-statslink"><a href="https://stats.wikimedia.org/#/en.wikipedia.org">Statistics</a></li> <li id="footer-places-cookiestatement"><a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Cookie_statement">Cookie statement</a></li> <li id="footer-places-mobileview"><a href="//en.m.wikipedia.org/w/index.php?title=Integrin_alpha_L&mobileaction=toggle_view_mobile" class="noprint stopMobileRedirectToggle">Mobile view</a></li> </ul> <ul id="footer-icons" class="noprint"> <li id="footer-copyrightico"><a href="https://wikimediafoundation.org/" class="cdx-button cdx-button--fake-button cdx-button--size-large cdx-button--fake-button--enabled"><picture><source media="(min-width: 500px)" srcset="/static/images/footer/wikimedia-button.svg" width="84" height="29"><img src="/static/images/footer/wikimedia.svg" width="25" height="25" alt="Wikimedia Foundation" lang="en" loading="lazy"></picture></a></li> <li id="footer-poweredbyico"><a href="https://www.mediawiki.org/" class="cdx-button cdx-button--fake-button cdx-button--size-large cdx-button--fake-button--enabled"><picture><source media="(min-width: 500px)" srcset="/w/resources/assets/poweredby_mediawiki.svg" width="88" height="31"><img src="/w/resources/assets/mediawiki_compact.svg" alt="Powered by MediaWiki" width="25" height="25" loading="lazy"></picture></a></li> </ul> </footer> </div> </div> </div> <div class="vector-header-container vector-sticky-header-container"> <div id="vector-sticky-header" class="vector-sticky-header"> <div class="vector-sticky-header-start"> <div class="vector-sticky-header-icon-start vector-button-flush-left vector-button-flush-right" aria-hidden="true"> <button class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-sticky-header-search-toggle" tabindex="-1" data-event-name="ui.vector-sticky-search-form.icon"><span class="vector-icon mw-ui-icon-search mw-ui-icon-wikimedia-search"></span> <span>Search</span> </button> </div> <div role="search" class="vector-search-box-vue vector-search-box-show-thumbnail vector-search-box"> <div class="vector-typeahead-search-container"> <div class="cdx-typeahead-search cdx-typeahead-search--show-thumbnail"> <form action="/w/index.php" id="vector-sticky-search-form" class="cdx-search-input cdx-search-input--has-end-button"> <div class="cdx-search-input__input-wrapper" data-search-loc="header-moved"> <div class="cdx-text-input cdx-text-input--has-start-icon"> <input class="cdx-text-input__input" type="search" name="search" placeholder="Search Wikipedia"> <span class="cdx-text-input__icon cdx-text-input__start-icon"></span> </div> <input type="hidden" name="title" value="Special:Search"> </div> <button class="cdx-button cdx-search-input__end-button">Search</button> </form> </div> </div> </div> <div class="vector-sticky-header-context-bar"> <nav aria-label="Contents" class="vector-toc-landmark"> <div id="vector-sticky-header-toc" class="vector-dropdown mw-portlet mw-portlet-sticky-header-toc vector-sticky-header-toc vector-button-flush-left" > <input type="checkbox" id="vector-sticky-header-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-sticky-header-toc" class="vector-dropdown-checkbox " aria-label="Toggle the table of contents" > <label id="vector-sticky-header-toc-label" for="vector-sticky-header-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Toggle the table of contents</span> </label> <div class="vector-dropdown-content"> <div id="vector-sticky-header-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <div class="vector-sticky-header-context-bar-primary" aria-hidden="true" ><span class="mw-page-title-main">Integrin alpha L</span></div> </div> </div> <div class="vector-sticky-header-end" aria-hidden="true"> <div class="vector-sticky-header-icons"> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only" id="ca-talk-sticky-header" tabindex="-1" data-event-name="talk-sticky-header"><span class="vector-icon mw-ui-icon-speechBubbles mw-ui-icon-wikimedia-speechBubbles"></span> <span></span> </a> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only" id="ca-subject-sticky-header" tabindex="-1" data-event-name="subject-sticky-header"><span class="vector-icon mw-ui-icon-article mw-ui-icon-wikimedia-article"></span> <span></span> </a> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only" id="ca-history-sticky-header" tabindex="-1" data-event-name="history-sticky-header"><span class="vector-icon mw-ui-icon-wikimedia-history mw-ui-icon-wikimedia-wikimedia-history"></span> <span></span> </a> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only mw-watchlink" id="ca-watchstar-sticky-header" tabindex="-1" data-event-name="watch-sticky-header"><span class="vector-icon mw-ui-icon-wikimedia-star mw-ui-icon-wikimedia-wikimedia-star"></span> <span></span> </a> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only" id="ca-edit-sticky-header" tabindex="-1" data-event-name="wikitext-edit-sticky-header"><span class="vector-icon mw-ui-icon-wikimedia-wikiText mw-ui-icon-wikimedia-wikimedia-wikiText"></span> <span></span> </a> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only" id="ca-ve-edit-sticky-header" tabindex="-1" data-event-name="ve-edit-sticky-header"><span class="vector-icon mw-ui-icon-wikimedia-edit mw-ui-icon-wikimedia-wikimedia-edit"></span> <span></span> </a> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only" id="ca-viewsource-sticky-header" tabindex="-1" data-event-name="ve-edit-protected-sticky-header"><span class="vector-icon mw-ui-icon-wikimedia-editLock mw-ui-icon-wikimedia-wikimedia-editLock"></span> <span></span> </a> </div> <div class="vector-sticky-header-buttons"> <button class="cdx-button cdx-button--weight-quiet mw-interlanguage-selector" id="p-lang-btn-sticky-header" tabindex="-1" data-event-name="ui.dropdown-p-lang-btn-sticky-header"><span class="vector-icon mw-ui-icon-wikimedia-language mw-ui-icon-wikimedia-wikimedia-language"></span> <span>9 languages</span> </button> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive" id="ca-addsection-sticky-header" tabindex="-1" data-event-name="addsection-sticky-header"><span class="vector-icon mw-ui-icon-speechBubbleAdd-progressive mw-ui-icon-wikimedia-speechBubbleAdd-progressive"></span> <span>Add topic</span> </a> </div> <div class="vector-sticky-header-icon-end"> <div class="vector-user-links"> </div> </div> </div> </div> </div> <div class="vector-settings" id="p-dock-bottom"> <ul></ul> </div><script>(RLQ=window.RLQ||[]).push(function(){mw.config.set({"wgHostname":"mw-web.codfw.main-d8647bfd6-rqrx7","wgBackendResponseTime":127,"wgPageParseReport":{"limitreport":{"cputime":"0.764","walltime":"1.144","ppvisitednodes":{"value":1816,"limit":1000000},"postexpandincludesize":{"value":166768,"limit":2097152},"templateargumentsize":{"value":609,"limit":2097152},"expansiondepth":{"value":8,"limit":100},"expensivefunctioncount":{"value":36,"limit":500},"unstrip-depth":{"value":1,"limit":20},"unstrip-size":{"value":117481,"limit":5000000},"entityaccesscount":{"value":36,"limit":400},"timingprofile":["100.00% 982.516 1 -total"," 59.50% 584.616 1 Template:Infobox_gene"," 12.69% 124.714 4 Template:Navbox"," 12.22% 120.099 22 Template:Cite_journal"," 10.98% 107.878 1 Template:PDB_Gallery"," 7.24% 71.163 1 Template:Short_description"," 5.20% 51.052 1 Template:Reflist"," 4.19% 41.201 2 Template:Pagetype"," 2.96% 29.095 1 Template:PDB_Gallery/3683"," 1.92% 18.876 1 Template:Gene-16-stub"]},"scribunto":{"limitreport-timeusage":{"value":"0.550","limit":"10.000"},"limitreport-memusage":{"value":7660065,"limit":52428800}},"cachereport":{"origin":"mw-api-ext.eqiad.main-7dc6c6fd7c-5c5np","timestamp":"20250204231917","ttl":2592000,"transientcontent":false}}});});</script> <script type="application/ld+json">{"@context":"https:\/\/schema.org","@type":"Article","name":"Integrin alpha L","url":"https:\/\/en.wikipedia.org\/wiki\/Integrin_alpha_L","sameAs":"http:\/\/www.wikidata.org\/entity\/Q3648604","mainEntity":"http:\/\/www.wikidata.org\/entity\/Q3648604","author":{"@type":"Organization","name":"Contributors to Wikimedia projects"},"publisher":{"@type":"Organization","name":"Wikimedia Foundation, Inc.","logo":{"@type":"ImageObject","url":"https:\/\/www.wikimedia.org\/static\/images\/wmf-hor-googpub.png"}},"datePublished":"2006-07-07T21:59:24Z","dateModified":"2024-06-10T08:31:07Z","image":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/3\/33\/Protein_ITGAL_PDB_1cqp.png"}</script> </body> </html>