Search results for: re-polymerization.

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re-polymerization.</title> <meta name="description" content="Search results for: re-polymerization."> <meta name="keywords" content="re-polymerization."> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block 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action="https://publications.waset.org/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="re-polymerization."> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 1</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: re-polymerization.</h1> <div class="card publication-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Realignment of f-actin Cytoskeleton in Osteocytes after Mechanical Loading</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/search?q=R.%20S.%20A.%20Nesbitt">R. S. A. Nesbitt</a>, <a href="https://publications.waset.org/search?q=J.%20Macione"> J. Macione</a>, <a href="https://publications.waset.org/search?q=E.%20Babollah"> E. Babollah</a>, <a href="https://publications.waset.org/search?q=B.%20Adu-baffour"> B. Adu-baffour</a>, <a href="https://publications.waset.org/search?q=S.%20P.%20Kotha"> S. P. Kotha</a> </p> <p class="card-text"><strong>Abstract:</strong></p> F-actin fibrils are the cytoskeleton of osteocytes. They react in a dynamic manner to mechanical loading, and strength and reposition their efforts to reinforce the cells structure. We hypothesize that f-actin is temporarly disrupted after loading and repolymerizes in a new orientation to oppose the applied load. In vitro studies are conducted to determine f-actin disruption after varying mechanical stimulus parameters that are known to affect bone formation. Results indicate that the f-actin cytoskeleton is disrupted in vitro as a function of applied mechanical stimulus parameters and that the f-actin bundles reassemble after loading induced disruption within 3 minutes after cessation of loading. The disruption of the factin cytoskeleton depends on the magnitude of stretch, the numbers of loading cycles, frequency, the insertion of rest between loading cycles and extracellular calcium. In vivo studies also demonstrate disruption of the f-actin cytoskeleton in cells embedded in the bone matrix immediately after mechanical loading. These studies suggest that adaptation of the f-actin fiber bundles of the cytoskeleton in response to applied loads occurs by disruption and subsequent repolymerization. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/search?q=Mechanical%20loading%20of%20osteocytes" title="Mechanical loading of osteocytes">Mechanical loading of osteocytes</a>, <a href="https://publications.waset.org/search?q=f-actin%20cytoskeleton" title=" f-actin cytoskeleton"> f-actin cytoskeleton</a>, <a href="https://publications.waset.org/search?q=disruption" title=" disruption"> disruption</a>, <a href="https://publications.waset.org/search?q=re-polymerization." title=" re-polymerization."> re-polymerization.</a> </p> <a href="https://publications.waset.org/2128/realignment-of-f-actin-cytoskeleton-in-osteocytes-after-mechanical-loading" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/2128/apa" target="_blank" rel="nofollow" class="btn 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Search results for: re-polymerization.