<?xml version="1.0" encoding="UTF-8" standalone="no"?> <!DOCTYPE svg PUBLIC "-//W3C//DTD SVG 1.1//EN" "http://www.w3.org/Graphics/SVG/1.1/DTD/svg11.dtd"> <!-- Generated by graphviz version 2.40.1 (20161225.0304) --> <!-- Title: test Pages: 1 --> <!-- BEGIN modified area --> <svg id="rgsvg" width="32.0in" height="32.0in" zoomAndPan="disable" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" xml:space="preserve"> <defs> <symbol id="checkBoxFill" overflow="visible"><g pointer-events="none" stroke="black" stroke-width="2"><rect x="-5" y="-5" width="10" height="10" fill="black" stroke="black" stroke-width="1" /></g></symbol> <symbol id="checkBoxCross" overflow="visible"><g pointer-events="none" stroke="black" stroke-width="2"><line x1="-5" y1="-5" x2="5" y2="5"/><line x1="5" y1="-5" x2="-5" y2="5"/></g></symbol> <symbol id="checkBoxRect" overflow="visible"><rect x="-7.5" y="-7.5" width="15" height="15" fill="white" stroke="black" stroke-width="1" cursor="pointer"/></symbol> <symbol id="highlightSymbol" overflow="visible"><circle r="100" stroke-width="5" stroke="black" fill-opacity=".5" cx="0" cy="0"/></symbol> <symbol id="mini_pie" overflow="visible"><g transform="scale(.125)"><g pointer-events="none" transform="rotate(0)"><path d="M0,0 0 -110 a110,110 0 0,1 95.2627944162882,55 z" fill-opacity=".9" stroke="black" stroke-width="5"/></g></g></symbol> <symbol id="mini_pie_exp" overflow="visible"><g transform="scale(.125)"><g pointer-events="none" transform="rotate(0)"><path d="M0,0 0 -110 a110,110 0 0,1 95.2627944162882,55 z" fill-opacity=".9" stroke="black" stroke-width="5"/><circle r="22" stroke-width="7" stroke="black" fill="#80FF80" fill-opacity=".9" cx="49.5" cy="-85.7365149746594"/></g></g></symbol> <symbol id="mini_pie_iss" overflow="visible"><g transform="scale(.125)"><g pointer-events="none" transform="rotate(0)"><path d="M0,0 0 -110 a110,110 0 0,1 95.2627944162882,55 z" fill-opacity=".9" stroke="black" stroke-width="5"/><circle r="22" stroke-width="7" stroke="black" fill="#8080FF" fill-opacity=".9" cx="49.5" cy="-85.7365149746594"/></g></g></symbol> <symbol id="miniHighlightSymbol" overflow="visible"><g transform="scale(.09)"><circle r="100" stroke-width="5" stroke="black" fill-opacity=".5" cx="0" cy="0"/></g></symbol> </defs> <g id="tform_matrix" transform="matrix(1, 0, 0, 1, 4, 1246)"> <g id="underlay_context_1"/> <g id="underlay_context_2"/> <g id="underlay_context_3"/> <!-- END modified area --> <!-- CHANGE: removed initial transformation. --> <g id="graph0" class="graph"> <!-- END modified area --> <title>test</title> <polygon fill="#ffffff" stroke="transparent" points="-4,4 -4,-1246 1867,-1246 1867,4 -4,4"/> <!-- node1 --> <g id="node1" class="node"> <title>node1</title> <polygon fill="#ffffff" stroke="transparent" points="1479.2695,-860.5 1378.2695,-860.5 1378.2695,-813.5 1479.2695,-813.5 1479.2695,-860.5"/> <polygon fill="none" stroke="#000000" points="1386.7695,-817 1386.7695,-856 1471.7695,-856 1471.7695,-817 1386.7695,-817"/> <text text-anchor="start" x="1401.7695" y="-845" font-family="Times,serif" font-size="10px" fill="#000000">GO:0110165</text> <text text-anchor="start" x="1389.7695" y="-834" font-family="Times,serif" font-size="10px" fill="#000000">cellular anatomical</text> <text text-anchor="start" x="1411.2695" y="-823" font-family="Times,serif" font-size="10px" fill="#000000">structure</text> </g> <!-- node2 --> <g id="node2" class="node"> <title>node2</title> <polygon fill="#ffffff" stroke="transparent" points="1467.2695,-772 1390.2695,-772 1390.2695,-736 1467.2695,-736 1467.2695,-772"/> <polygon fill="none" stroke="#000000" points="1398.7695,-740 1398.7695,-768 1459.7695,-768 1459.7695,-740 1398.7695,-740"/> <text text-anchor="start" x="1401.7695" y="-757" font-family="Times,serif" font-size="10px" fill="#000000">GO:0030054</text> <text text-anchor="start" x="1403.2695" y="-746" font-family="Times,serif" font-size="10px" fill="#000000">cell junction</text> </g> <!-- node1&#45;&gt;node2 --> <g id="edge52" class="edge"> <title>node1&#45;&gt;node2</title> <path fill="none" stroke="#000000" stroke-width="2" d="M1428.7695,-813.4375C1428.7695,-800.3056 1428.7695,-784.2065 1428.7695,-772.0769"/> </g> <!-- node32 --> <g id="node32" class="node"> <title>node32</title> <polygon fill="#ffffff" stroke="transparent" points="1467.2695,-689 1390.2695,-689 1390.2695,-653 1467.2695,-653 1467.2695,-689"/> <polygon fill="none" stroke="#000000" points="1398.7695,-657 1398.7695,-685 1459.7695,-685 1459.7695,-657 1398.7695,-657"/> <text text-anchor="start" x="1401.7695" y="-674" font-family="Times,serif" font-size="10px" fill="#000000">GO:0045202</text> <text text-anchor="start" x="1412.7695" y="-663" font-family="Times,serif" font-size="10px" fill="#000000">synapse</text> </g> <!-- node2&#45;&gt;node32 --> <g id="edge29" class="edge"> <title>node2&#45;&gt;node32</title> <path fill="none" stroke="#000000" stroke-width="2" d="M1428.7695,-735.9902C1428.7695,-722.1637 1428.7695,-703.1501 1428.7695,-689.2612"/> </g> <!-- node3 --> <g id="node3" class="node"> <title>node3</title> <polygon fill="#ffffff" stroke="transparent" points="1365.7695,-932 1261.7695,-932 1261.7695,-896 1365.7695,-896 1365.7695,-932"/> <polygon fill="none" stroke="#000000" points="1269.7695,-900 1269.7695,-928 1357.7695,-928 1357.7695,-900 1269.7695,-900"/> <text text-anchor="start" x="1286.2695" y="-917" font-family="Times,serif" font-size="10px" fill="#000000">GO:0005575</text> <text text-anchor="start" x="1272.7695" y="-906" font-family="Times,serif" font-size="10px" fill="#000000">cellular_component</text> </g> <!-- node3&#45;&gt;node1 --> <g id="edge5" class="edge"> <title>node3&#45;&gt;node1</title> <path fill="none" stroke="#000000" stroke-width="2" d="M1340.7319,-895.9469C1356.3994,-885.4565 1376.3282,-872.1129 1393.2611,-860.7752"/> </g> <!-- node4 --> <g id="node4" class="node"> <title>node4</title> <polygon fill="#ffffff" stroke="transparent" points="1159.7695,-528.5 1079.7695,-528.5 1079.7695,-481.5 1159.7695,-481.5 1159.7695,-528.5"/> <polygon fill="none" stroke="#000000" points="1087.7695,-485 1087.7695,-524 1151.7695,-524 1151.7695,-485 1087.7695,-485"/> <text text-anchor="start" x="1092.2695" y="-513" font-family="Times,serif" font-size="10px" fill="#000000">GO:0099537</text> <text text-anchor="start" x="1090.7695" y="-502" font-family="Times,serif" font-size="10px" fill="#000000">trans&#45;synaptic</text> <text text-anchor="start" x="1100.2695" y="-491" font-family="Times,serif" font-size="10px" fill="#000000">signaling</text> </g> <!-- node5 --> <g id="node5" class="node"> <title>node5</title> <polygon fill="#ffffff" stroke="transparent" points="949.7695,-445 869.7695,-445 869.7695,-387 949.7695,-387 949.7695,-445"/> <polygon fill="none" stroke="#000000" points="877.7695,-391 877.7695,-441 941.7695,-441 941.7695,-391 877.7695,-391"/> <text text-anchor="start" x="882.2695" y="-430" font-family="Times,serif" font-size="10px" fill="#000000">GO:0099177</text> <text text-anchor="start" x="883.2695" y="-419" font-family="Times,serif" font-size="10px" fill="#000000">regulation of</text> <text text-anchor="start" x="880.7695" y="-408" font-family="Times,serif" font-size="10px" fill="#000000">trans&#45;synaptic</text> <text text-anchor="start" x="890.2695" y="-397" font-family="Times,serif" font-size="10px" fill="#000000">signaling</text> </g> <!-- node4&#45;&gt;node5 --> <g id="edge51" class="edge"> <title>node4&#45;&gt;node5</title> <path fill="none" stroke="#2f4f4f" stroke-width="2" d="M1079.2794,-487.8399C1041.974,-472.0295 986.9307,-448.7016 949.7787,-432.9563"/> </g> <!-- node13 --> <g id="node13" class="node"> <title>node13</title> <polygon fill="#ffffff" stroke="transparent" points="1175.7695,-445 1095.7695,-445 1095.7695,-387 1175.7695,-387 1175.7695,-445"/> <polygon fill="none" stroke="#000000" points="1103.7695,-391 1103.7695,-441 1167.7695,-441 1167.7695,-391 1103.7695,-391"/> <text text-anchor="start" x="1108.2695" y="-430" font-family="Times,serif" font-size="10px" fill="#000000">GO:0098916</text> <text text-anchor="start" x="1111.2695" y="-419" font-family="Times,serif" font-size="10px" fill="#000000">anterograde</text> <text text-anchor="start" x="1106.7695" y="-408" font-family="Times,serif" font-size="10px" fill="#000000">trans&#45;synaptic</text> <text text-anchor="start" x="1116.2695" y="-397" font-family="Times,serif" font-size="10px" fill="#000000">signaling</text> </g> <!-- node4&#45;&gt;node13 --> <g id="edge50" class="edge"> <title>node4&#45;&gt;node13</title> <path fill="none" stroke="#000000" stroke-width="2" d="M1124.0572,-481.1496C1126.0381,-470.1308 1128.4092,-456.9415 1130.4983,-445.3211"/> </g> <!-- node21 --> <g id="node21" class="node"> <title>node21</title> <polygon fill="#ffffff" stroke="transparent" points="964.7695,-268 868.7695,-268 868.7695,-210 964.7695,-210 964.7695,-268"/> <polygon fill="none" stroke="#000000" points="876.7695,-214 876.7695,-264 956.7695,-264 956.7695,-214 876.7695,-214"/> <text text-anchor="start" x="889.2695" y="-253" font-family="Times,serif" font-size="10px" fill="#000000">GO:0050804</text> <text text-anchor="start" x="887.7695" y="-242" font-family="Times,serif" font-size="10px" fill="#000000">modulation of</text> <text text-anchor="start" x="879.7695" y="-231" font-family="Times,serif" font-size="10px" fill="#000000">chemical synaptic</text> <text text-anchor="start" x="890.7695" y="-220" font-family="Times,serif" font-size="10px" fill="#000000">transmission</text> </g> <!-- node5&#45;&gt;node21 --> <g id="edge48" class="edge"> <title>node5&#45;&gt;node21</title> <path fill="none" stroke="#000000" stroke-width="2" d="M910.9254,-386.772C912.2224,-353.9768 914.3142,-301.0844 915.6119,-268.2714"/> </g> <!-- node6 --> <g id="node6" class="node"> <title>node6</title> <polygon fill="#ffffff" stroke="transparent" points="1288.2695,-268 1209.2695,-268 1209.2695,-210 1288.2695,-210 1288.2695,-268"/> <polygon fill="none" stroke="#000000" points="1217.7695,-214 1217.7695,-264 1280.7695,-264 1280.7695,-214 1217.7695,-214"/> <text text-anchor="start" x="1221.7695" y="-253" font-family="Times,serif" font-size="10px" fill="#000000">GO:0035249</text> <text text-anchor="start" x="1231.7695" y="-242" font-family="Times,serif" font-size="10px" fill="#000000">synaptic</text> <text text-anchor="start" x="1222.2695" y="-231" font-family="Times,serif" font-size="10px" fill="#000000">transmission,</text> <text text-anchor="start" x="1220.7695" y="-220" font-family="Times,serif" font-size="10px" fill="#000000">glutamatergic</text> </g> <!-- node7 --> <g id="node7" class="node"> <title>node7</title> <polygon fill="#ffffff" stroke="transparent" points="1141.7695,-69.5 1041.7695,-69.5 1041.7695,-.5 1141.7695,-.5 1141.7695,-69.5"/> <polygon fill="none" stroke="#000000" points="1049.7695,-4 1049.7695,-65 1133.7695,-65 1133.7695,-4 1049.7695,-4"/> <text text-anchor="start" x="1064.2695" y="-54" font-family="Times,serif" font-size="10px" fill="#000000">GO:0051968</text> <text text-anchor="start" x="1052.7695" y="-43" font-family="Times,serif" font-size="10px" fill="#000000">positive regulation</text> <text text-anchor="start" x="1068.7695" y="-32" font-family="Times,serif" font-size="10px" fill="#000000">of synaptic</text> <text text-anchor="start" x="1064.7695" y="-21" font-family="Times,serif" font-size="10px" fill="#000000">transmission,</text> <text text-anchor="start" x="1063.2695" y="-10" font-family="Times,serif" font-size="10px" fill="#000000">glutamatergic</text> </g> <!-- node6&#45;&gt;node7 --> <g id="edge31" class="edge"> <title>node6&#45;&gt;node7</title> <path fill="none" stroke="#008000" stroke-width="2" d="M1226.2752,-209.7718C1197.7862,-172.7541 1148.7622,-109.0542 1118.4246,-69.6347"/> </g> <!-- node18 --> <g id="node18" class="node"> <title>node18</title> <polygon fill="#ffffff" stroke="transparent" points="1131.2695,-174.5 1052.2695,-174.5 1052.2695,-105.5 1131.2695,-105.5 1131.2695,-174.5"/> <polygon fill="none" stroke="#000000" points="1060.7695,-109 1060.7695,-170 1123.7695,-170 1123.7695,-109 1060.7695,-109"/> <text text-anchor="start" x="1064.7695" y="-159" font-family="Times,serif" font-size="10px" fill="#000000">GO:0051966</text> <text text-anchor="start" x="1065.7695" y="-148" font-family="Times,serif" font-size="10px" fill="#000000">regulation of</text> <text text-anchor="start" x="1074.7695" y="-137" font-family="Times,serif" font-size="10px" fill="#000000">synaptic</text> <text text-anchor="start" x="1065.2695" y="-126" font-family="Times,serif" font-size="10px" fill="#000000">transmission,</text> <text text-anchor="start" x="1063.7695" y="-115" font-family="Times,serif" font-size="10px" fill="#000000">glutamatergic</text> </g> <!-- node6&#45;&gt;node18 --> <g id="edge30" class="edge"> <title>node6&#45;&gt;node18</title> <path fill="none" stroke="#2f4f4f" stroke-width="2" d="M1209.1518,-214.0181C1185.3518,-199.0105 1155.1723,-179.9801 1131.3746,-164.9739"/> </g> <!-- node8 --> <g id="node8" class="node"> <title>node8</title> <polygon fill="#ffffff" stroke="transparent" points="1144.7695,-351.5 1048.7695,-351.5 1048.7695,-304.5 1144.7695,-304.5 1144.7695,-351.5"/> <polygon fill="none" stroke="#000000" points="1056.7695,-308 1056.7695,-347 1136.7695,-347 1136.7695,-308 1056.7695,-308"/> <text text-anchor="start" x="1069.2695" y="-336" font-family="Times,serif" font-size="10px" fill="#000000">GO:0007268</text> <text text-anchor="start" x="1059.7695" y="-325" font-family="Times,serif" font-size="10px" fill="#000000">chemical synaptic</text> <text text-anchor="start" x="1070.7695" y="-314" font-family="Times,serif" font-size="10px" fill="#000000">transmission</text> </g> <!-- node8&#45;&gt;node6 --> <g id="edge10" class="edge"> <title>node8&#45;&gt;node6</title> <path fill="none" stroke="#000000" stroke-width="2" d="M1137.1037,-304.3833C1159.3552,-291.3544 1186.882,-275.2368 1209.0373,-262.2643"/> </g> <!-- node8&#45;&gt;node21 --> <g id="edge11" class="edge"> <title>node8&#45;&gt;node21</title> <path fill="none" stroke="#2f4f4f" stroke-width="2" d="M1049.0054,-304.3833C1023.0715,-291.5604 991.0866,-275.7457 965.07,-262.8819"/> </g> <!-- node34 --> <g id="node34" class="node"> <title>node34</title> <polygon fill="#ffffff" stroke="transparent" points="892.7695,-169 792.7695,-169 792.7695,-111 892.7695,-111 892.7695,-169"/> <polygon fill="none" stroke="#000000" points="800.7695,-115 800.7695,-165 884.7695,-165 884.7695,-115 800.7695,-115"/> <text text-anchor="start" x="815.2695" y="-154" font-family="Times,serif" font-size="10px" fill="#000000">GO:0050806</text> <text text-anchor="start" x="803.7695" y="-143" font-family="Times,serif" font-size="10px" fill="#000000">positive regulation</text> <text text-anchor="start" x="819.7695" y="-132" font-family="Times,serif" font-size="10px" fill="#000000">of synaptic</text> <text text-anchor="start" x="816.7695" y="-121" font-family="Times,serif" font-size="10px" fill="#000000">transmission</text> </g> <!-- node8&#45;&gt;node34 --> <g id="edge12" class="edge"> <title>node8&#45;&gt;node34</title> <path fill="none" stroke="#008000" stroke-width="2" d="M1075.7497,-304.2772C1052.4811,-278.9126 1013.0493,-238.5014 973.7695,-210 948.62,-191.7515 918.1219,-175.173 892.8825,-162.7354"/> </g> <!-- node9 --> <g id="node9" class="node"> <title>node9</title> <polygon fill="#ffffff" stroke="transparent" points="905.2695,-860.5 808.2695,-860.5 808.2695,-813.5 905.2695,-813.5 905.2695,-860.5"/> <polygon fill="none" stroke="#000000" points="816.7695,-817 816.7695,-856 897.7695,-856 897.7695,-817 816.7695,-817"/> <text text-anchor="start" x="829.7695" y="-845" font-family="Times,serif" font-size="10px" fill="#000000">GO:0050789</text> <text text-anchor="start" x="830.7695" y="-834" font-family="Times,serif" font-size="10px" fill="#000000">regulation of</text> <text text-anchor="start" x="819.7695" y="-823" font-family="Times,serif" font-size="10px" fill="#000000">biological process</text> </g> <!-- node10 --> <g id="node10" class="node"> <title>node10</title> <polygon fill="#ffffff" stroke="transparent" points="1248.2695,-694.5 1171.2695,-694.5 1171.2695,-647.5 1248.2695,-647.5 1248.2695,-694.5"/> <polygon fill="none" stroke="#000000" points="1179.7695,-651 1179.7695,-690 1240.7695,-690 1240.7695,-651 1179.7695,-651"/> <text text-anchor="start" x="1182.7695" y="-679" font-family="Times,serif" font-size="10px" fill="#000000">GO:0023051</text> <text text-anchor="start" x="1183.7695" y="-668" font-family="Times,serif" font-size="10px" fill="#000000">regulation of</text> <text text-anchor="start" x="1190.7695" y="-657" font-family="Times,serif" font-size="10px" fill="#000000">signaling</text> </g> <!-- node9&#45;&gt;node10 --> <g id="edge36" class="edge"> <title>node9&#45;&gt;node10</title> <path fill="none" stroke="#000000" stroke-width="2" d="M905.4936,-823.9241C941.9192,-813.3868 992.5074,-797.1204 1034.7695,-777.5 1086.3837,-753.5378 1141.8396,-717.9268 1176.1732,-694.5882"/> </g> <!-- node24 --> <g id="node24" class="node"> <title>node24</title> <polygon fill="#ffffff" stroke="transparent" points="1026.2695,-772 949.2695,-772 949.2695,-736 1026.2695,-736 1026.2695,-772"/> <polygon fill="none" stroke="#000000" points="957.7695,-740 957.7695,-768 1018.7695,-768 1018.7695,-740 957.7695,-740"/> <text text-anchor="start" x="960.7695" y="-757" font-family="Times,serif" font-size="10px" fill="#000000">GO:0023052</text> <text text-anchor="start" x="968.7695" y="-746" font-family="Times,serif" font-size="10px" fill="#000000">signaling</text> </g> <!-- node9&#45;&gt;node24 --> <g id="edge37" class="edge"> <title>node9&#45;&gt;node24</title> <path fill="none" stroke="#000000" stroke-width="2" d="M893.9585,-813.4375C914.6847,-800.3056 940.0941,-784.2065 959.2385,-772.0769"/> </g> <!-- node27 --> <g id="node27" class="node"> <title>node27</title> <polygon fill="#ffffff" stroke="transparent" points="511.7695,-777.5 425.7695,-777.5 425.7695,-730.5 511.7695,-730.5 511.7695,-777.5"/> <polygon fill="none" stroke="#000000" points="433.7695,-734 433.7695,-773 503.7695,-773 503.7695,-734 433.7695,-734"/> <text text-anchor="start" x="441.2695" y="-762" font-family="Times,serif" font-size="10px" fill="#000000">GO:0050794</text> <text text-anchor="start" x="442.2695" y="-751" font-family="Times,serif" font-size="10px" fill="#000000">regulation of</text> <text text-anchor="start" x="436.7695" y="-740" font-family="Times,serif" font-size="10px" fill="#000000">cellular process</text> </g> <!-- node9&#45;&gt;node27 --> <g id="edge39" class="edge"> <title>node9&#45;&gt;node27</title> <path fill="none" stroke="#000000" stroke-width="2" d="M808.0219,-826.572C731.5954,-810.2231 584.7962,-778.8201 511.9546,-763.238"/> </g> <!-- node30 --> <g id="node30" class="node"> <title>node30</title> <polygon fill="#ffffff" stroke="transparent" points="787.2695,-777.5 680.2695,-777.5 680.2695,-730.5 787.2695,-730.5 787.2695,-777.5"/> <polygon fill="none" stroke="#000000" points="688.7695,-734 688.7695,-773 779.7695,-773 779.7695,-734 688.7695,-734"/> <text text-anchor="start" x="706.7695" y="-762" font-family="Times,serif" font-size="10px" fill="#000000">GO:0048518</text> <text text-anchor="start" x="695.2695" y="-751" font-family="Times,serif" font-size="10px" fill="#000000">positive regulation</text> <text text-anchor="start" x="691.7695" y="-740" font-family="Times,serif" font-size="10px" fill="#000000">of biological process</text> </g> <!-- node9&#45;&gt;node30 --> <g id="edge38" class="edge"> <title>node9&#45;&gt;node30</title> <path fill="none" stroke="#000000" stroke-width="2" d="M821.8517,-813.4375C805.2321,-802.2227 785.4055,-788.8438 768.7747,-777.6214"/> </g> <!-- node10&#45;&gt;node5 --> <g id="edge24" class="edge"> <title>node10&#45;&gt;node5</title> <path fill="none" stroke="#000000" stroke-width="2" d="M1171.0838,-661.5257C1139.4468,-652.4235 1094.7155,-636.3431 1061.7695,-611.5 999.9807,-564.9078 949.9359,-487.1837 925.6676,-445.1413"/> </g> <!-- node33 --> <g id="node33" class="node"> <title>node33</title> <polygon fill="#ffffff" stroke="transparent" points="797.7695,-611.5 697.7695,-611.5 697.7695,-564.5 797.7695,-564.5 797.7695,-611.5"/> <polygon fill="none" stroke="#000000" points="705.7695,-568 705.7695,-607 789.7695,-607 789.7695,-568 705.7695,-568"/> <text text-anchor="start" x="720.2695" y="-596" font-family="Times,serif" font-size="10px" fill="#000000">GO:0023056</text> <text text-anchor="start" x="708.7695" y="-585" font-family="Times,serif" font-size="10px" fill="#000000">positive regulation</text> <text text-anchor="start" x="723.2695" y="-574" font-family="Times,serif" font-size="10px" fill="#000000">of signaling</text> </g> <!-- node10&#45;&gt;node33 --> <g id="edge23" class="edge"> <title>node10&#45;&gt;node33</title> <path fill="none" stroke="#000000" stroke-width="2" d="M1171.1743,-664.0662C1087.7881,-649.0856 890.8583,-613.7064 797.949,-597.0149"/> </g> <!-- node11 --> <g id="node11" class="node"> <title>node11</title> <polygon fill="#ffffff" stroke="transparent" points="1794.7695,-1093 1690.7695,-1093 1690.7695,-1057 1794.7695,-1057 1794.7695,-1093"/> <polygon fill="none" stroke="#000000" points="1698.7695,-1061 1698.7695,-1089 1786.7695,-1089 1786.7695,-1061 1698.7695,-1061"/> <text text-anchor="start" x="1701.7695" y="-1078" font-family="Times,serif" font-size="10px" fill="#000000">UBERON:0001062</text> <text text-anchor="start" x="1706.7695" y="-1067" font-family="Times,serif" font-size="10px" fill="#000000">anatomical entity</text> </g> <!-- node12 --> <g id="node12" class="node"> <title>node12</title> <polygon fill="#ffffff" stroke="transparent" points="1794.7695,-1015.5 1690.7695,-1015.5 1690.7695,-968.5 1794.7695,-968.5 1794.7695,-1015.5"/> <polygon fill="none" stroke="#000000" points="1698.7695,-972 1698.7695,-1011 1786.7695,-1011 1786.7695,-972 1698.7695,-972"/> <text text-anchor="start" x="1701.7695" y="-1000" font-family="Times,serif" font-size="10px" fill="#000000">UBERON:0000465</text> <text text-anchor="start" x="1702.2695" y="-989" font-family="Times,serif" font-size="10px" fill="#000000">material anatomical</text> <text text-anchor="start" x="1730.2695" y="-978" font-family="Times,serif" font-size="10px" fill="#000000">entity</text> </g> <!-- node11&#45;&gt;node12 --> <g id="edge55" class="edge"> <title>node11&#45;&gt;node12</title> <path fill="none" stroke="#000000" stroke-width="2" d="M1742.7695,-1056.9902C1742.7695,-1044.8801 1742.7695,-1028.7908 1742.7695,-1015.6508"/> </g> <!-- node15 --> <g id="node15" class="node"> <title>node15</title> <polygon fill="#ffffff" stroke="transparent" points="1650.2695,-932 1545.2695,-932 1545.2695,-896 1650.2695,-896 1650.2695,-932"/> <polygon fill="none" stroke="#000000" points="1553.7695,-900 1553.7695,-928 1642.7695,-928 1642.7695,-900 1553.7695,-900"/> <text text-anchor="start" x="1557.2695" y="-917" font-family="Times,serif" font-size="10px" fill="#000000">UBERON:0000061</text> <text text-anchor="start" x="1556.7695" y="-906" font-family="Times,serif" font-size="10px" fill="#000000">anatomical structure</text> </g> <!-- node12&#45;&gt;node15 --> <g id="edge54" class="edge"> <title>node12&#45;&gt;node15</title> <path fill="none" stroke="#000000" stroke-width="2" d="M1698.8712,-968.3858C1677.1992,-956.7277 1651.4664,-942.8852 1631.3856,-932.0831"/> </g> <!-- node13&#45;&gt;node8 --> <g id="edge47" class="edge"> <title>node13&#45;&gt;node8</title> <path fill="none" stroke="#000000" stroke-width="2" d="M1122.7831,-386.6973C1117.731,-375.2976 1112.0198,-362.4109 1107.2384,-351.6222"/> </g> <!-- node14 --> <g id="node14" class="node"> <title>node14</title> <polygon fill="#ffffff" stroke="transparent" points="1507.7695,-1015.5 1395.7695,-1015.5 1395.7695,-968.5 1507.7695,-968.5 1507.7695,-1015.5"/> <polygon fill="none" stroke="#000000" points="1403.7695,-972 1403.7695,-1011 1499.7695,-1011 1499.7695,-972 1403.7695,-972"/> <text text-anchor="start" x="1417.2695" y="-1000" font-family="Times,serif" font-size="10px" fill="#000000">CARO:0000003</text> <text text-anchor="start" x="1406.7695" y="-989" font-family="Times,serif" font-size="10px" fill="#000000">connected anatomical</text> <text text-anchor="start" x="1433.7695" y="-978" font-family="Times,serif" font-size="10px" fill="#000000">structure</text> </g> <!-- node14&#45;&gt;node15 --> <g id="edge2" class="edge"> <title>node14&#45;&gt;node15</title> <path fill="none" stroke="#000000" stroke-width="2" d="M1495.9705,-968.3858C1517.792,-956.7277 1543.7023,-942.8852 1563.9216,-932.0831"/> </g> <!-- node15&#45;&gt;node1 --> <g id="edge53" class="edge"> <title>node15&#45;&gt;node1</title> <path fill="none" stroke="#000000" stroke-width="2" d="M1558.1465,-895.9469C1534.6343,-885.2342 1504.5917,-871.5462 1479.3758,-860.0573"/> </g> <!-- node16 --> <g id="node16" class="node"> <title>node16</title> <polygon fill="#ffffff" stroke="transparent" points="573.7695,-694.5 473.7695,-694.5 473.7695,-647.5 573.7695,-647.5 573.7695,-694.5"/> <polygon fill="none" stroke="#000000" points="481.7695,-651 481.7695,-690 565.7695,-690 565.7695,-651 481.7695,-651"/> <text text-anchor="start" x="496.2695" y="-679" font-family="Times,serif" font-size="10px" fill="#000000">GO:0048522</text> <text text-anchor="start" x="484.7695" y="-668" font-family="Times,serif" font-size="10px" fill="#000000">positive regulation</text> <text text-anchor="start" x="486.7695" y="-657" font-family="Times,serif" font-size="10px" fill="#000000">of cellular process</text> </g> <!-- node17 --> <g id="node17" class="node"> <title>node17</title> <polygon fill="#ffffff" stroke="transparent" points="379.7695,-611.5 265.7695,-611.5 265.7695,-564.5 379.7695,-564.5 379.7695,-611.5"/> <polygon fill="none" stroke="#000000" points="273.7695,-568 273.7695,-607 371.7695,-607 371.7695,-568 273.7695,-568"/> <text text-anchor="start" x="295.2695" y="-596" font-family="Times,serif" font-size="10px" fill="#000000">GO:0010647</text> <text text-anchor="start" x="283.7695" y="-585" font-family="Times,serif" font-size="10px" fill="#000000">positive regulation</text> <text text-anchor="start" x="276.7695" y="-574" font-family="Times,serif" font-size="10px" fill="#000000">of cell communication</text> </g> <!-- node16&#45;&gt;node17 --> <g id="edge35" class="edge"> <title>node16&#45;&gt;node17</title> <path fill="none" stroke="#000000" stroke-width="2" d="M473.5672,-650.2697C445.0789,-638.5059 409.3255,-623.742 379.7832,-611.543"/> </g> <!-- node17&#45;&gt;node34 --> <g id="edge22" class="edge"> <title>node17&#45;&gt;node34</title> <path fill="none" stroke="#000000" stroke-width="2" d="M344.0719,-564.328C370.1157,-532.8491 410.7695,-474.3639 410.7695,-416 410.7695,-416 410.7695,-416 410.7695,-328 410.7695,-245.5923 678.4113,-176.4386 792.3682,-150.7292"/> </g> <!-- node18&#45;&gt;node7 --> <g id="edge45" class="edge"> <title>node18&#45;&gt;node7</title> <path fill="none" stroke="#000000" stroke-width="2" d="M1091.7695,-105.3281C1091.7695,-93.859 1091.7695,-81.1019 1091.7695,-69.6355"/> </g> <!-- node19 --> <g id="node19" class="node"> <title>node19</title> <polygon fill="#ffffff" stroke="transparent" points="428.7695,-855 342.7695,-855 342.7695,-819 428.7695,-819 428.7695,-855"/> <polygon fill="none" stroke="#000000" points="350.7695,-823 350.7695,-851 420.7695,-851 420.7695,-823 350.7695,-823"/> <text text-anchor="start" x="358.2695" y="-840" font-family="Times,serif" font-size="10px" fill="#000000">GO:0009987</text> <text text-anchor="start" x="353.7695" y="-829" font-family="Times,serif" font-size="10px" fill="#000000">cellular process</text> </g> <!-- node19&#45;&gt;node16 --> <g id="edge18" class="edge"> <title>node19&#45;&gt;node16</title> <path fill="none" stroke="#008000" stroke-width="2" d="M386.8815,-818.8874C389.1422,-796.0248 395.9962,-756.5447 416.7695,-730.5 431.4149,-712.1382 453.3528,-698.5421 473.559,-689.0187"/> </g> <!-- node25 --> <g id="node25" class="node"> <title>node25</title> <polygon fill="#ffffff" stroke="transparent" points="171.7695,-772 67.7695,-772 67.7695,-736 171.7695,-736 171.7695,-772"/> <polygon fill="none" stroke="#000000" points="75.7695,-740 75.7695,-768 163.7695,-768 163.7695,-740 75.7695,-740"/> <text text-anchor="start" x="92.2695" y="-757" font-family="Times,serif" font-size="10px" fill="#000000">GO:0007154</text> <text text-anchor="start" x="78.7695" y="-746" font-family="Times,serif" font-size="10px" fill="#000000">cell communication</text> </g> <!-- node19&#45;&gt;node25 --> <g id="edge17" class="edge"> <title>node19&#45;&gt;node25</title> <path fill="none" stroke="#000000" stroke-width="2" d="M342.7364,-823.5724C296.1251,-809.0283 221.7607,-785.8243 171.877,-770.2591"/> </g> <!-- node19&#45;&gt;node27 --> <g id="edge19" class="edge"> <title>node19&#45;&gt;node27</title> <path fill="none" stroke="#2f4f4f" stroke-width="2" d="M403.7793,-818.9902C415.8894,-806.8801 431.9787,-790.7908 445.1187,-777.6508"/> </g> <!-- node20 --> <g id="node20" class="node"> <title>node20</title> <polygon fill="#ffffff" stroke="transparent" points="721.7695,-1010 621.7695,-1010 621.7695,-974 721.7695,-974 721.7695,-1010"/> <polygon fill="none" stroke="#000000" points="629.7695,-978 629.7695,-1006 713.7695,-1006 713.7695,-978 629.7695,-978"/> <text text-anchor="start" x="644.2695" y="-995" font-family="Times,serif" font-size="10px" fill="#000000">GO:0008150</text> <text text-anchor="start" x="632.7695" y="-984" font-family="Times,serif" font-size="10px" fill="#000000">biological_process</text> </g> <!-- node20&#45;&gt;node9 --> <g id="edge15" class="edge"> <title>node20&#45;&gt;node9</title> <path fill="none" stroke="#2f4f4f" stroke-width="2" d="M693.3534,-973.9162C726.9041,-945.8062 791.5622,-891.6331 828.6971,-860.5201"/> </g> <!-- node20&#45;&gt;node19 --> <g id="edge13" class="edge"> <title>node20&#45;&gt;node19</title> <path fill="none" stroke="#000000" stroke-width="2" d="M638.4019,-973.9162C583.4401,-944.1291 474.4785,-885.0765 419.3667,-855.2082"/> </g> <!-- node20&#45;&gt;node30 --> <g id="edge14" class="edge"> <title>node20&#45;&gt;node30</title> <path fill="none" stroke="#008000" stroke-width="2" d="M676.5316,-973.7197C687.647,-931.0509 715.2938,-824.9231 727.6426,-777.5195"/> </g> <!-- node35 --> <g id="node35" class="node"> <title>node35</title> <polygon fill="#ffffff" stroke="transparent" points="961.2695,-932 852.2695,-932 852.2695,-896 961.2695,-896 961.2695,-932"/> <polygon fill="none" stroke="#000000" points="860.7695,-900 860.7695,-928 953.7695,-928 953.7695,-900 860.7695,-900"/> <text text-anchor="start" x="879.7695" y="-917" font-family="Times,serif" font-size="10px" fill="#000000">GO:0065007</text> <text text-anchor="start" x="863.7695" y="-906" font-family="Times,serif" font-size="10px" fill="#000000">biological regulation</text> </g> <!-- node20&#45;&gt;node35 --> <g id="edge16" class="edge"> <title>node20&#45;&gt;node35</title> <path fill="none" stroke="#000000" stroke-width="2" d="M721.8947,-975.3627C760.1775,-962.6561 812.8723,-945.1659 852.212,-932.1085"/> </g> <!-- node21&#45;&gt;node18 --> <g id="edge43" class="edge"> <title>node21&#45;&gt;node18</title> <path fill="none" stroke="#000000" stroke-width="2" d="M965.0523,-211.6857C992.4693,-196.1755 1026.3633,-177.0012 1052.1968,-162.3868"/> </g> <!-- node21&#45;&gt;node34 --> <g id="edge42" class="edge"> <title>node21&#45;&gt;node34</title> <path fill="none" stroke="#000000" stroke-width="2" d="M894.9673,-209.8322C885.4175,-197.0561 874.2328,-182.0927 864.6716,-169.3014"/> </g> <!-- node22 --> <g id="node22" class="node"> <title>node22</title> <polygon fill="#ffffff" stroke="transparent" points="1168.7695,-606 1070.7695,-606 1070.7695,-570 1168.7695,-570 1168.7695,-606"/> <polygon fill="none" stroke="#000000" points="1078.7695,-574 1078.7695,-602 1160.7695,-602 1160.7695,-574 1078.7695,-574"/> <text text-anchor="start" x="1092.2695" y="-591" font-family="Times,serif" font-size="10px" fill="#000000">GO:0099536</text> <text text-anchor="start" x="1081.7695" y="-580" font-family="Times,serif" font-size="10px" fill="#000000">synaptic signaling</text> </g> <!-- node22&#45;&gt;node4 --> <g id="edge49" class="edge"> <title>node22&#45;&gt;node4</title> <path fill="none" stroke="#000000" stroke-width="2" d="M1119.7695,-569.9902C1119.7695,-557.8801 1119.7695,-541.7908 1119.7695,-528.6508"/> </g> <!-- node23 --> <g id="node23" class="node"> <title>node23</title> <polygon fill="#ffffff" stroke="transparent" points="1015.7695,-689 919.7695,-689 919.7695,-653 1015.7695,-653 1015.7695,-689"/> <polygon fill="none" stroke="#000000" points="927.7695,-657 927.7695,-685 1007.7695,-685 1007.7695,-657 927.7695,-657"/> <text text-anchor="start" x="940.2695" y="-674" font-family="Times,serif" font-size="10px" fill="#000000">GO:0007267</text> <text text-anchor="start" x="930.7695" y="-663" font-family="Times,serif" font-size="10px" fill="#000000">cell&#45;cell signaling</text> </g> <!-- node23&#45;&gt;node22 --> <g id="edge9" class="edge"> <title>node23&#45;&gt;node22</title> <path fill="none" stroke="#000000" stroke-width="2" d="M1000.7513,-652.9902C1026.1594,-639.116 1061.1324,-620.0189 1086.59,-606.1177"/> </g> <!-- node24&#45;&gt;node10 --> <g id="edge26" class="edge"> <title>node24&#45;&gt;node10</title> <path fill="none" stroke="#2f4f4f" stroke-width="2" d="M1026.439,-739.5425C1067.0614,-724.3549 1130.5758,-700.6084 1171.1714,-685.4308"/> </g> <!-- node24&#45;&gt;node23 --> <g id="edge25" class="edge"> <title>node24&#45;&gt;node23</title> <path fill="none" stroke="#000000" stroke-width="2" d="M983.4298,-735.9902C980.0981,-722.1637 975.5165,-703.1501 972.1698,-689.2612"/> </g> <!-- node24&#45;&gt;node33 --> <g id="edge27" class="edge"> <title>node24&#45;&gt;node33</title> <path fill="none" stroke="#008000" stroke-width="2" d="M961.6284,-735.9191C918.0136,-705.7522 830.4197,-645.1664 781.9634,-611.6508"/> </g> <!-- node25&#45;&gt;node17 --> <g id="edge8" class="edge"> <title>node25&#45;&gt;node17</title> <path fill="none" stroke="#008000" stroke-width="2" d="M130.9544,-735.8365C145.7815,-712.9202 173.8258,-673.3833 205.7695,-647.5 223.6521,-633.0102 245.6358,-620.6922 265.7011,-611.0879"/> </g> <!-- node25&#45;&gt;node23 --> <g id="edge6" class="edge"> <title>node25&#45;&gt;node23</title> <path fill="none" stroke="#000000" stroke-width="2" d="M171.8571,-748.9018C324.9154,-733.9209 771.7848,-690.1825 919.6422,-675.7106"/> </g> <!-- node26 --> <g id="node26" class="node"> <title>node26</title> <polygon fill="#ffffff" stroke="transparent" points="306.7695,-694.5 214.7695,-694.5 214.7695,-647.5 306.7695,-647.5 306.7695,-694.5"/> <polygon fill="none" stroke="#000000" points="222.7695,-651 222.7695,-690 298.7695,-690 298.7695,-651 222.7695,-651"/> <text text-anchor="start" x="233.2695" y="-679" font-family="Times,serif" font-size="10px" fill="#000000">GO:0010646</text> <text text-anchor="start" x="225.7695" y="-668" font-family="Times,serif" font-size="10px" fill="#000000">regulation of cell</text> <text text-anchor="start" x="228.7695" y="-657" font-family="Times,serif" font-size="10px" fill="#000000">communication</text> </g> <!-- node25&#45;&gt;node26 --> <g id="edge7" class="edge"> <title>node25&#45;&gt;node26</title> <path fill="none" stroke="#2f4f4f" stroke-width="2" d="M150.3644,-735.9902C170.937,-723.8801 198.2695,-707.7908 220.5916,-694.6508"/> </g> <!-- node26&#45;&gt;node5 --> <g id="edge21" class="edge"> <title>node26&#45;&gt;node5</title> <path fill="none" stroke="#000000" stroke-width="2" d="M306.9237,-652.8655C428.4066,-605.1334 755.5161,-476.608 869.7449,-431.7262"/> </g> <!-- node26&#45;&gt;node17 --> <g id="edge20" class="edge"> <title>node26&#45;&gt;node17</title> <path fill="none" stroke="#000000" stroke-width="2" d="M278.3704,-647.4375C286.7477,-636.2227 296.7416,-622.8438 305.1246,-611.6214"/> </g> <!-- node27&#45;&gt;node16 --> <g id="edge41" class="edge"> <title>node27&#45;&gt;node16</title> <path fill="none" stroke="#000000" stroke-width="2" d="M484.3832,-730.4375C491.8147,-719.2227 500.6803,-705.8438 508.1168,-694.6214"/> </g> <!-- node27&#45;&gt;node26 --> <g id="edge40" class="edge"> <title>node27&#45;&gt;node26</title> <path fill="none" stroke="#000000" stroke-width="2" d="M425.6718,-736.8023C391.0448,-722.9848 342.5102,-703.6177 307.0626,-689.4727"/> </g> <!-- node28 --> <g id="node28" class="node"> <title>node28</title> <polygon fill="#ffffff" stroke="transparent" points="1497.2695,-1242 1406.2695,-1242 1406.2695,-1206 1497.2695,-1206 1497.2695,-1242"/> <polygon fill="none" stroke="#000000" points="1414.7695,-1210 1414.7695,-1238 1489.7695,-1238 1489.7695,-1210 1414.7695,-1210"/> <text text-anchor="start" x="1417.7695" y="-1227" font-family="Times,serif" font-size="10px" fill="#000000">CARO:0030000</text> <text text-anchor="start" x="1417.7695" y="-1216" font-family="Times,serif" font-size="10px" fill="#000000">biological entity</text> </g> <!-- node29 --> <g id="node29" class="node"> <title>node29</title> <polygon fill="#ffffff" stroke="transparent" points="1498.7695,-1170 1404.7695,-1170 1404.7695,-1134 1498.7695,-1134 1498.7695,-1170"/> <polygon fill="none" stroke="#000000" points="1412.7695,-1138 1412.7695,-1166 1490.7695,-1166 1490.7695,-1138 1412.7695,-1138"/> <text text-anchor="start" x="1417.2695" y="-1155" font-family="Times,serif" font-size="10px" fill="#000000">CARO:0000000</text> <text text-anchor="start" x="1415.7695" y="-1144" font-family="Times,serif" font-size="10px" fill="#000000">anatomical entity</text> </g> <!-- node28&#45;&gt;node29 --> <g id="edge4" class="edge"> <title>node28&#45;&gt;node29</title> <path fill="none" stroke="#000000" stroke-width="2" d="M1451.7695,-1205.8314C1451.7695,-1195 1451.7695,-1181.2876 1451.7695,-1170.4133"/> </g> <!-- node31 --> <g id="node31" class="node"> <title>node31</title> <polygon fill="#ffffff" stroke="transparent" points="1503.2695,-1098.5 1400.2695,-1098.5 1400.2695,-1051.5 1503.2695,-1051.5 1503.2695,-1098.5"/> <polygon fill="none" stroke="#000000" points="1408.7695,-1055 1408.7695,-1094 1495.7695,-1094 1495.7695,-1055 1408.7695,-1055"/> <text text-anchor="start" x="1417.7695" y="-1083" font-family="Times,serif" font-size="10px" fill="#000000">CARO:0000006</text> <text text-anchor="start" x="1411.7695" y="-1072" font-family="Times,serif" font-size="10px" fill="#000000">material anatomical</text> <text text-anchor="start" x="1439.7695" y="-1061" font-family="Times,serif" font-size="10px" fill="#000000">entity</text> </g> <!-- node29&#45;&gt;node31 --> <g id="edge1" class="edge"> <title>node29&#45;&gt;node31</title> <path fill="none" stroke="#000000" stroke-width="2" d="M1451.7695,-1133.7521C1451.7695,-1123.2566 1451.7695,-1109.9539 1451.7695,-1098.6619"/> </g> <!-- node30&#45;&gt;node16 --> <g id="edge34" class="edge"> <title>node30&#45;&gt;node16</title> <path fill="none" stroke="#000000" stroke-width="2" d="M680.2343,-732.8408C647.5457,-719.921 606.0158,-703.5069 573.9582,-690.8365"/> </g> <!-- node30&#45;&gt;node33 --> <g id="edge33" class="edge"> <title>node30&#45;&gt;node33</title> <path fill="none" stroke="#000000" stroke-width="2" d="M735.7754,-730.2162C738.4368,-698.6597 743.1079,-643.274 745.7674,-611.7396"/> </g> <!-- node31&#45;&gt;node14 --> <g id="edge3" class="edge"> <title>node31&#45;&gt;node14</title> <path fill="none" stroke="#000000" stroke-width="2" d="M1451.7695,-1051.4375C1451.7695,-1040.2227 1451.7695,-1026.8438 1451.7695,-1015.6214"/> </g> <!-- node32&#45;&gt;node22 --> <g id="edge32" class="edge"> <title>node32&#45;&gt;node22</title> <path fill="none" stroke="#66cdaa" stroke-width="2" d="M1390.2592,-660.6558C1334.2823,-645.6199 1230.4344,-617.7255 1168.9796,-601.2183"/> </g> <!-- node33&#45;&gt;node34 --> <g id="edge28" class="edge"> <title>node33&#45;&gt;node34</title> <path fill="none" stroke="#000000" stroke-width="2" d="M746.1986,-564.3637C744.1347,-531.2215 740.7695,-469.0473 740.7695,-416 740.7695,-416 740.7695,-416 740.7695,-328 740.7695,-265.6161 784.6973,-204.1462 814.8976,-169.2572"/> </g> <!-- node34&#45;&gt;node7 --> <g id="edge44" class="edge"> <title>node34&#45;&gt;node7</title> <path fill="none" stroke="#000000" stroke-width="2" d="M892.8589,-118.878C936.1737,-100.6127 998.4688,-74.3437 1041.7602,-56.0883"/> </g> <!-- node35&#45;&gt;node9 --> <g id="edge46" class="edge"> <title>node35&#45;&gt;node9</title> <path fill="none" stroke="#000000" stroke-width="2" d="M894.9202,-895.7521C888.1049,-885.2566 879.4669,-871.9539 872.1344,-860.6619"/> </g> </g> <!-- BEGIN modified area bottom --><g id="overlay_context"></g></g><g id="control_context"></g><g id="detail_context"></g><g id="super_context"></g></svg><!-- END modified area -->