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Volume 635 Issue 8039, 21 November 2024

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Issue 8039, 21 November 2024</h1> <nav class="u-hide-print" data-track-component="issue navigation" aria-label="issue navigation" role="navigation"> <ul class="c-pagination app-pagination-borderless"> <li class="c-pagination__item"> <a href="/nature/volumes/635/issues/8038" class="c-pagination__link" data-track="click" data-track-action="previous link" data-track-label="link"> <svg class="u-flex-static u-mr-8 c-pagination__icon c-pagination__icon--active u-hide u-show-at-sm" aria-hidden="true" focusable="false"> <use xlink:href="#icon-springer-arrow-left"></use> </svg><span>Previous issue</span></a> </li> <li class="c-pagination__item"> <a href="/nature/volumes/635" class="c-pagination__link" data-track="click" data-track-action="view volume 635" data-track-label="link"> <span>Volume 635</span></a> </li> </ul> </nav> </div> <div class="l-with-sidebar" style="--with-sidebar--gap:0;--with-sidebar--min:58%"> <div class="app-volumes-cover" data-test="issue-cover-container"> <div class="app-volumes-cover__copy" data-test="issue-description"> <div> <h2 class="u-h3">Cell nav</h2> <p data-promo-text data-promo-text-threshold="560"><a href="https://www.nature.com/immersive/d42859-024-00060-5/index.html">The Human Cell Atlas (HCA) initiative</a> was set up to create comprehensive reference maps of all the body’s cells in a bid to increase understanding of human health and disease. This week, the HCA consortium presents early drafts of a number of maps alongside analytical tools in a <a href="https://www.nature.com/collections/jccbbdahji">collection of papers published across Nature Portfolio and Genome Biology</a>. In <i>Nature</i>, <a href="https://doi.org/10.1038/s41586-024-08189-z">Ken To and colleagues</a> map early fetal skeletal development, identifying gene networks that drive bone formation. In a second paper, <a href="https://doi.org/10.1038/s41586-023-06806-x">Bao Zhang and co-workers</a> reveal gene programs that orchestrate the differentiation of bone, muscle and neural tissue in a map of human embryonic limb development. In a third paper, <a href="https://doi.org/10.1038/s41586-024-08002-x">Nusayhah Gopee and colleagues</a> map the fetal development of skin, identifying the role played by immune cells in the formation of hair follicles and the vascular network. A fourth paper sees <a href="https://doi.org/10.1038/s41586-024-08172-8">Zhisong He and co-workers</a> present an integrated brain organoid cell atlas, which provides insights into how well organoids capture aspects of the developing brain. In a fifth paper, <a href="https://doi.org/10.1038/s41586-024-07571-1">Amanda Oliver and colleagues</a> map the gastrointestinal tract to create an atlas and uncover disease-related cellular changes in conditions such as Crohn’s disease and ulcerative colitis. Finally, a detailed thymus map from <a href="https://doi.org/10.1038/s41586-024-07944-6">Nadav Yayon and co-workers</a> tracks the development of immune cells. The cover images captures the breadth of the HCA initiative, overlaying a subway-style network of biological systems on a detailed cellular map.</p> <p class="app-volumes-cover__image-copy-text" data-test="issue-image-credit" data-credit="Cover artwork: Claire Agosti (SayoStudio); concept: Ania Hupalowska">Cover artwork: Claire Agosti (SayoStudio); concept: Ania Hupalowska</p> </div> </div> <div class="app-volumes-cover__image"> <img src="https://media.springernature.com/w440/springer-static/cover-hires/journal/41586/635/8039" alt="Volume 635 Issue 8039" data-test="issue-cover-image"/> <p class="u-mt-16 u-mb-0"> <a href="/nature/subscribe" class="u-button u-button--primary u-button--full-width" data-test="issue-page-subscribe-button" data-track="click" data-track-action="subscribe" data-track-category="nature-issue-page" data-track-label="button">Subscribe</a> </p> </div> </div> <div class="l-with-sidebar__sidebar" style="--with-sidebar--basis: 385px;" data-test="issue-toc-container"> <aside class="u-full-height app-toc u-pa-16" aria-label="Issue navigation" class="hide-print"> <div data-container-type="issue-reading-companion"> <div class="clear cleared" data-component=reading-companion-placeholder> <div data-component=reading-companion-sticky> <nav id="toc"> <div data-component="reading-companion-sections"> <h1 class="app-toc__title">Table of Contents</h1> <ol class="u-list-reset u-mb-0" data-component="reading-companion-section-items"> <li class="app-toc__item" data-section="0"> <a href="#ThisWeek" data-id="ThisWeek" data-track="click" data-track-action="section anchor" data-track-category="reading companion" data-track-label="link:This Week" class="u-display-block u-pt-8 u-pb-8">This Week</a> </li> <li class="app-toc__item" data-section="1"> <a href="#NewsinFocus" data-id="NewsinFocus" data-track="click" data-track-action="section anchor" data-track-category="reading companion" data-track-label="link:News in Focus" class="u-display-block u-pt-8 u-pb-8">News in Focus</a> </li> <li class="app-toc__item" data-section="2"> <a href="#BooksandArts" data-id="BooksandArts" data-track="click" data-track-action="section anchor" data-track-category="reading companion" data-track-label="link:Books &amp; Arts" class="u-display-block u-pt-8 u-pb-8">Books &amp; Arts</a> </li> <li class="app-toc__item" data-section="3"> <a href="#Opinion" data-id="Opinion" data-track="click" data-track-action="section anchor" data-track-category="reading companion" data-track-label="link:Opinion" class="u-display-block u-pt-8 u-pb-8">Opinion</a> </li> <li class="app-toc__item" data-section="4"> <a href="#Work" data-id="Work" data-track="click" data-track-action="section anchor" data-track-category="reading companion" data-track-label="link:Work" class="u-display-block u-pt-8 u-pb-8">Work</a> </li> <li class="app-toc__item" data-section="5"> <a href="#Research" data-id="Research" data-track="click" data-track-action="section anchor" data-track-category="reading companion" data-track-label="link:Research" class="u-display-block u-pt-8 u-pb-8">Research</a> </li> <li class="app-toc__item" data-section="6"> <a href="#AmendmentsandCorrections" data-id="AmendmentsandCorrections" data-track="click" data-track-action="section anchor" data-track-category="reading companion" data-track-label="link:Amendments &amp; Corrections" class="u-display-block u-pt-8 u-pb-8">Amendments &amp; Corrections</a> </li> <li class="app-toc__item" data-section="7"> <a href="#NatureIndex" data-id="NatureIndex" data-track="click" data-track-action="section anchor" data-track-category="reading companion" data-track-label="link:Nature Index" class="u-display-block u-pt-8 u-pb-8">Nature Index</a> </li> </ol> </div> </nav> </div> </div> </div> </aside> </div> </div> <div data-track-component="issue section list"> <section id="ThisWeek" aria-labelledby="ThisWeek" class="u-mb-48 u-mt-48" data-container-type=issue-section-list data-track-component="issue section list"> <div class="c-section-heading" data-test="title"> <h2>This Week</h2> </div> <ul class="app-article-list-row"> <li> <h3 class="c-section-heading c-section-heading--no-bt">Editorial</h3> <ul class="app-article-list-row"> <li class="app-article-list-row__item"> <div class="u-full-height"> <div class="app-article-list-row__mpu"> <article class="u-full-height c-card c-card--flush c-card--major" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/d41586-024-03754-y" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">A ‘Wikipedia for cells’: researchers get an updated look at the Human Cell Atlas, and it’s remarkable</a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Coming less than a decade after its launch, the studies emerging from the global project are a major achievement. Funders should sign up for the long haul.</p> </div> <div> <p class="u-mr-8 u-display-inline">Collection: </p> <ul class="u-list-reset u-display-inline"> <li class="c-pill"> <a href="/collections/jccbbdahji" data-track="click" data-track-action="view collection" data-track-label="link">The Human Cell Atlas: towards a first draft atlas</a> </li> </ul> </div> </div> </div> <div class="c-meta "> <span class="c-meta__item c-meta__item--block-at-lg" > <span class="c-meta__type">Editorial</span> </span> <time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-20" itemprop="datePublished">20 Nov 2024</time> </div> </article> <div class="c-ad c-ad--300x250" data-test="issue-page-mpu-ad"> <div class="c-ad__inner"> <div id="div-gpt-ad-right-2" class="div-gpt-ad medium-rectangle c-ad c-ad--300x250 advert js-ad hide-print grade-c-hide" data-ad-type="right" data-test="right-ad" data-pa11y-ignore data-gpt data-gpt-unitpath="/285/nature.com/issue" data-gpt-sizes="300x250" data-gpt-targeting="pos=right;artid=/nature/volumes/635/issues/8039;path=/nature/volumes/635/issues/8039" > <noscript> <a href="//pubads.g.doubleclick.net/gampad/jump?iu=/285/nature.com/issue&amp;sz=300x250&amp;c=405101336&amp;t=pos%3Dright%26artid%3D/nature/volumes/635/issues/8039"> <img data-test="gpt-advert-fallback-img" src="//pubads.g.doubleclick.net/gampad/ad?iu=/285/nature.com/issue&amp;sz=300x250&amp;c=405101336&amp;t=pos%3Dright%26artid%3D/nature/volumes/635/issues/8039" alt="Advertisement" width="300" height="250"/> </a> </noscript> </div> <p class="c-ad__label u-mb-0 u-mt-8">Advertisement</p> </div> </div> </div> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/d41586-024-03753-z" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">‘Forever’ chemicals can be destroyed with clever chemistry — now test these techniques outside the lab</a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Chemistry that can break carbon–fluorine bonds in persistent molecules called PFAS could help to clean up the environment. Testing in real-world settings must come next.</p> </div> </div> </div> <div class="c-meta "> <span class="c-meta__item c-meta__item--block-at-lg" > <span class="c-meta__type">Editorial</span> </span> <time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-20" itemprop="datePublished">20 Nov 2024</time> </div> </article> </div> </li> </ul> </li> <li> <h3 class="c-section-heading c-section-heading--no-bt">World View</h3> <ul class="app-article-list-row"> <li class="app-article-list-row__item"> <div class="u-full-height"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/d41586-024-03735-1" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Why it’s in rich nations’ interests to fund climate finance</a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Wealthy countries face a stark choice — pay poorer ones to help them decarbonize now or face escalating climate damages at home.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact u-mb-16"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Alissa M. Kleinnijenhuis</span></li> </ul> </div> </div> <div class="c-meta "> <span class="c-meta__item c-meta__item--block-at-lg" > <span class="c-meta__type">World View</span> </span> <time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-13" itemprop="datePublished">13 Nov 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/d41586-024-03755-x" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">How the world will weather Trump’s withdrawal from global agreements</a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>The US president-elect says he will pull the country out of international treaties and partnerships. 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data-track-label="link">Rice is not as nice with global warming</a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Harvest records from Japan and China suggest that high night-time temperatures reduce the quality of rice, a staple food for billions of people.</p> </div> </div> </div> <div class="c-meta "> <span class="c-meta__item c-meta__item--block-at-lg" > <span class="c-meta__type">Research Highlight</span> </span> <time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-12" itemprop="datePublished">12 Nov 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/d41586-024-03671-0" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Reducing pregnancy risk could be as easy as chewing gum</a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Clinical trial in Malawi suggests that chewing gum sweetened with the natural compound xylitol is linked to a lower risk of preterm birth.</p> </div> </div> </div> <div class="c-meta "> <span class="c-meta__item c-meta__item--block-at-lg" > <span class="c-meta__type">Research Highlight</span> </span> <time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-13" itemprop="datePublished">13 Nov 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 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<div class="c-section-heading" data-test="title"> <h2>News in Focus</h2> </div> <ul class="app-article-list-row"> <li> <h3 class="c-section-heading c-section-heading--no-bt">News</h3> <ul class="app-article-list-row"> <li class="app-article-list-row__item"> <div class="u-full-height"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/d41586-024-03647-0" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">This scientist treated her own cancer with viruses she grew in the lab</a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Virologist Beata Halassy says self-treatment worked and was a positive experience — but researchers warn that it is not something others should try.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact u-mb-16"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Zoe Corbyn</span></li> </ul> <div> <p class="u-mr-8 u-display-inline">Collection: </p> <ul class="u-list-reset u-display-inline"> <li class="c-pill"> <a href="/collections/bpwtvhdwgf" data-track="click" data-track-action="view collection" data-track-label="link">Cancer at Nature Portfolio</a> </li> </ul> </div> </div> </div> <div class="c-meta "> <span class="c-meta__item c-meta__item--block-at-lg" > <span class="c-meta__type">News</span> </span> <time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-08" itemprop="datePublished">08 Nov 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/d41586-024-03629-2" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Should Alzheimer’s be diagnosed with a blood test? 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data-track-label="link">Computational technologies of the Human Cell Atlas</a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>As the international effort reaches a ‘critical mass’ of achievements, <i>Nature</i> highlights seven tools that are poised to enable the next set of discoveries.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact u-mb-16"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Amber Dance</span></li> </ul> <div> <p class="u-mr-8 u-display-inline">Collections: </p> <ul class="u-list-reset u-display-inline"> <li class="c-pill"> <a href="/collections/jccbbdahji" data-track="click" data-track-action="view collection" data-track-label="link">The Human Cell Atlas: towards a first draft atlas</a> </li> <li class="c-pill"> <a href="/collections/fxvqrpnlcq" data-track="click" data-track-action="view collection" data-track-label="link">NatureTech</a> </li> </ul> </div> </div> </div> <div class="c-meta "> <span class="c-meta__item c-meta__item--block-at-lg" > <span class="c-meta__type">Technology Feature</span> </span> <time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-20" itemprop="datePublished">20 Nov 2024</time> </div> </article> </div> </li> </ul> </li> <li> <h3 class="c-section-heading c-section-heading--no-bt">Where I Work</h3> <ul class="app-article-list-row"> <li class="app-article-list-row__item"> <div class="u-full-height"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/d41586-024-03763-x" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">What a forest’s glow can reveal about the impact of environmental change</a> 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Light-activated catalysts have been discovered that take them apart with ease.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact u-mb-16"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Jinyong Liu</span></li> </ul> </div> </div> <div class="c-meta "> <span class="c-meta__item c-meta__item--block-at-lg" > <span class="c-meta__type">News &amp; Views</span> </span> <time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-20" itemprop="datePublished">20 Nov 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/d41586-024-03469-0" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Division of labour: mitochondria split to meet energy demands</a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>How do mitochondria, the cell’s energy-producing organelles, perform competing metabolic processes? 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itemprop="name">Jiang Liu</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Yongcai He</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Xixiang Xu</span></li> </ul> </div> </div> <div class="c-meta "> <span class="c-meta__item c-meta__item--block-at-lg" > <span class="c-meta__type">Article</span> </span> <time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-09-05" itemprop="datePublished">05 Sept 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41586-024-08110-8" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Silicon heterojunction back-contact solar cells by laser patterning</a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>We fabricated silicon heterojunction back-contact solar cells using laser patterning, producing cells that exceeded 27% power-conversion efficiency.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated u-mb-16"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Hua Wu</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Feng Ye</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Xixiang Xu</span></li> </ul> </div> </div> <div class="c-meta "> <span class="c-meta__item c-meta__item--block-at-lg" > <span class="c-meta__type">Article</span> </span> <time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-10-01" itemprop="datePublished">01 Oct 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41586-024-08179-1" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Photocatalytic low-temperature defluorination of PFASs</a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Photocatalysis at 40–60 °C is shown to be able to defluorinate perfluoroalkyl substances, known as ‘forever chemicals’, allowing the recycling of fluorine in polyfluoroalkyl and perfluoroalkyl substances as inorganic fluoride salt.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated u-mb-16"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Hao Zhang</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Jin-Xiang Chen</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Yan-Biao Kang</span></li> </ul> </div> </div> <div class="c-meta "> <span class="c-meta__item c-meta__item--block-at-lg" > <span class="c-meta__type">Article</span> </span> <time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-20" itemprop="datePublished">20 Nov 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41586-024-08230-1" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Early-twentieth-century cold bias in ocean surface temperature observations</a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Independent statistical reconstructions of the global mean surface temperature from either ocean or land data show that existing estimates of early-twentieth-century ocean surface temperatures are too cold.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated u-mb-16"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Sebastian Sippel</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Elizabeth C. Kent</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Reto Knutti</span></li> </ul> </div> </div> <div class="c-meta "> <span class="c-meta__item c-meta__item--block-at-lg" > <span class="c-meta__type">Article</span> </span> <span class="c-meta__item c-meta__item--block-at-lg" itemprop="openAccess" data-test="open-access"><span class="u-color-open-access">Open Access</span></span> <time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-20" itemprop="datePublished">20 Nov 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41586-024-08154-w" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Keeping the global consumption within the planetary boundaries</a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>An analysis of the environmental footprints of consumption finds that planetary boundary transgressions can be mitigated by following an effective mitigation pathway focused on the food and services sectors and high-expenditure consumers.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated u-mb-16"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Peipei Tian</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Honglin Zhong</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Klaus Hubacek</span></li> </ul> </div> </div> <div class="c-meta "> <span class="c-meta__item c-meta__item--block-at-lg" > <span class="c-meta__type">Article</span> </span> <span class="c-meta__item c-meta__item--block-at-lg" itemprop="openAccess" data-test="open-access"><span class="u-color-open-access">Open Access</span></span> <time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-13" itemprop="datePublished">13 Nov 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41586-024-08089-2" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Global influence of soil texture on ecosystem water limitation</a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Through their effects on soil hydraulic properties,&#xa0;soil texture and sand content are shown to have&#xa0;broad implications for the terrestrial water cycle and carbon sink, and specific implications for vital ecosystems that are vulnerable to drought, especially with changing climate.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated u-mb-16"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">F. J. P. Wankmüller</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">L. Delval</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">A. Carminati</span></li> </ul> </div> </div> <div class="c-meta "> <span class="c-meta__item c-meta__item--block-at-lg" > <span class="c-meta__type">Article</span> </span> <span class="c-meta__item c-meta__item--block-at-lg" itemprop="openAccess" data-test="open-access"><span class="u-color-open-access">Open Access</span></span> <time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-10-23" itemprop="datePublished">23 Oct 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41586-024-08047-y" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Mosquito taste responses to human and floral cues guide biting and feeding</a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Taste neurons of the mosquito <i>Aedes</i> <i>albopictus</i> regulate biting, feeding and egg-laying behaviours by responding to taste cues in human sweat, nectar and egg-laying sites via excitation or inhibition.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated u-mb-16"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Lisa S. Baik</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Gaëlle J. S. Talross</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">John R. Carlson</span></li> </ul> </div> </div> <div class="c-meta "> <span class="c-meta__item c-meta__item--block-at-lg" > <span class="c-meta__type">Article</span> </span> <time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-10-16" itemprop="datePublished">16 Oct 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41586-024-08186-2" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Releasing a sugar brake generates sweeter tomato without yield penalty</a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>A study identifies two genes that act as brakes controlling the sugar content of tomatoes and demonstrates their manipulation to generate sweeter tomatoes without affecting the fruit size and yield.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated u-mb-16"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Jinzhe Zhang</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Hongjun Lyu</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Sanwen Huang</span></li> </ul> </div> </div> <div class="c-meta "> <span class="c-meta__item c-meta__item--block-at-lg" > <span class="c-meta__type">Article</span> </span> <span class="c-meta__item c-meta__item--block-at-lg" itemprop="openAccess" data-test="open-access"><span class="u-color-open-access">Open Access</span></span> <time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-13" itemprop="datePublished">13 Nov 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41586-024-08189-z" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">A multi-omic atlas of human embryonic skeletal development</a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>A multiomic atlas of human embryonic joint and cranium development enables detailed analysis of bone and cartilage maturation.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated u-mb-16"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Ken To</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Lijiang Fei</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Sarah A. Teichmann</span></li> </ul> <div> <p class="u-mr-8 u-display-inline">Collection: </p> <ul class="u-list-reset u-display-inline"> <li class="c-pill"> <a href="/collections/jccbbdahji" data-track="click" data-track-action="view collection" data-track-label="link">The Human Cell Atlas: towards a first draft atlas</a> </li> </ul> </div> </div> </div> <div class="c-meta "> <span class="c-meta__item c-meta__item--block-at-lg" > <span class="c-meta__type">Article</span> </span> <span class="c-meta__item c-meta__item--block-at-lg" itemprop="openAccess" data-test="open-access"><span class="u-color-open-access">Open Access</span></span> <time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-20" itemprop="datePublished">20 Nov 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41586-023-06806-x" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">A human embryonic limb cell atlas resolved in space and time</a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Using single-cell and spatial transcriptomics, human embryonic limb development across space and time and the diversification and cross-species&#xa0;conservation&#xa0;of cells are demonstrated.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated u-mb-16"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Bao Zhang</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Peng He</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Sarah A. Teichmann</span></li> </ul> <div> <p class="u-mr-8 u-display-inline">Collections: </p> <ul class="u-list-reset u-display-inline"> <li class="c-pill"> <a href="/collections/jccbbdahji" data-track="click" data-track-action="view collection" data-track-label="link">The Human Cell Atlas: towards a first draft atlas</a> </li> <li class="c-pill"> <a href="/collections/ccabegigec" data-track="click" data-track-action="view collection" data-track-label="link">Spatial Biology </a> </li> </ul> </div> </div> </div> <div class="c-meta "> <span class="c-meta__item c-meta__item--block-at-lg" > <span class="c-meta__type">Article</span> </span> <span class="c-meta__item c-meta__item--block-at-lg" itemprop="openAccess" data-test="open-access"><span class="u-color-open-access">Open Access</span></span> <time class="c-meta__item c-meta__item--block-at-lg" datetime="2023-12-06" itemprop="datePublished">06 Dec 2023</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41586-024-08002-x" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">A prenatal skin atlas reveals immune regulation of human skin morphogenesis</a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>A comprehensive multi-omics reference atlas of prenatal human skin shows that innate immune cells crosstalk with non-immune cells to perform pivotal roles in skin morphogenesis, including the formation of hair follicles.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated u-mb-16"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Nusayhah Hudaa Gopee</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Elena Winheim</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Muzlifah Haniffa</span></li> </ul> <div> <p class="u-mr-8 u-display-inline">Collection: </p> <ul class="u-list-reset u-display-inline"> <li class="c-pill"> <a href="/collections/jccbbdahji" data-track="click" data-track-action="view collection" data-track-label="link">The Human Cell Atlas: towards a first draft atlas</a> </li> </ul> </div> </div> </div> <div class="c-meta "> <span class="c-meta__item c-meta__item--block-at-lg" > <span class="c-meta__type">Article</span> </span> <span class="c-meta__item c-meta__item--block-at-lg" itemprop="openAccess" data-test="open-access"><span class="u-color-open-access">Open Access</span></span> <time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-10-16" itemprop="datePublished">16 Oct 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41586-024-08172-8" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">An integrated transcriptomic cell atlas of human neural organoids</a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>A human neural organoid cell atlas integrating 36 single-cell transcriptomic datasets shows cell types and states and estimates transcriptomic similarity between primary and organoid counterparts, showing potential to assess organoid fidelity and facilitate protocol development.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated u-mb-16"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Zhisong He</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Leander Dony</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Barbara Treutlein</span></li> </ul> <div> <p class="u-mr-8 u-display-inline">Collection: </p> <ul class="u-list-reset u-display-inline"> <li class="c-pill"> <a href="/collections/jccbbdahji" data-track="click" data-track-action="view collection" data-track-label="link">The Human Cell Atlas: towards a first draft atlas</a> </li> </ul> </div> </div> </div> <div class="c-meta "> <span class="c-meta__item c-meta__item--block-at-lg" > <span class="c-meta__type">Article</span> </span> <span class="c-meta__item c-meta__item--block-at-lg" itemprop="openAccess" data-test="open-access"><span class="u-color-open-access">Open Access</span></span> <time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-20" itemprop="datePublished">20 Nov 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41586-024-07571-1" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Single-cell integration reveals metaplasia in inflammatory gut diseases</a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>The study provides a comprehensive transcriptomic atlas of the human gastrointestinal tract across the lifespan, highlighting inflammation-induced changes in epithelial stem cells that alter mucosal architecture and promote further inflammation.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated u-mb-16"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Amanda J. Oliver</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Ni Huang</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Sarah A. Teichmann</span></li> </ul> <div> <p class="u-mr-8 u-display-inline">Collection: </p> <ul class="u-list-reset u-display-inline"> <li class="c-pill"> <a href="/collections/jccbbdahji" data-track="click" data-track-action="view collection" data-track-label="link">The Human Cell Atlas: towards a first draft atlas</a> </li> </ul> </div> </div> </div> <div class="c-meta "> <span class="c-meta__item c-meta__item--block-at-lg" > <span class="c-meta__type">Article</span> </span> <span class="c-meta__item c-meta__item--block-at-lg" itemprop="openAccess" data-test="open-access"><span class="u-color-open-access">Open Access</span></span> <time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-20" itemprop="datePublished">20 Nov 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41586-024-07944-6" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">A spatial human thymus cell atlas mapped to a continuous tissue axis</a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>A quantitative morphological framework for the human thymus&#xa0;reveals the establishment of the lobular cytokine network, canonical thymocyte trajectories and thymic epithelial cell distributions in fetal and paediatric thymic development.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated u-mb-16"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Nadav Yayon</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Veronika R. Kedlian</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Sarah A. 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