<?xml version="1.0" encoding="UTF-8"?> <article key="pdf/9999333" mdate="2014-08-05 00:00:00"> <author>Vladimir V. Iakovlev and Erin T. Carey and John Steege</author> <title>Pathology of Explanted Transvaginal Meshes</title> <pages>549 - 552</pages> <year>2014</year> <volume>8</volume> <number>9</number> <journal>International Journal of Medical and Health Sciences</journal> <ee>https://publications.waset.org/pdf/9999333</ee> <url>https://publications.waset.org/vol/93</url> <publisher>World Academy of Science, Engineering and Technology</publisher> <abstract>The use of polypropylene mesh devices for Pelvic Organ Prolapse (POP) spread rapidly during the last decade, yet our knowledge of the meshtissue interaction is far from complete. We aimed to perform a thorough pathological examination of explanted POP meshes and describe findings that may explain mechanisms of complications resulting in product excision. We report a spectrum of important findings, including nerve ingrowth, mesh deformation, involvement of detrusor muscle with neural ganglia, and polypropylene degradation. Analysis of these findings may improve and guide future treatment strategies. </abstract> <index>Open Science Index 93, 2014</index> </article>