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<li class="dropdown"> <a href="#" class="dropdown-toggle" role="button"> Register </a> <ul role="menu" class="dropdown-menu"> <li class=""> <a href="https://register.cambridgeinnovationinstitute.com/reg/imx" target="_self">Individual Pricing</a> </li> <li class=""> <a href="https://register.cambridgeinnovationinstitute.com/reg/imx/group" target="_self">Group Pricing</a> </li> <li class=""> <a href="https://register.cambridgeinnovationinstitute.com/reg/imx/ondemand" target="_self">On-Demand</a> </li> </ul> </li> </ul> </div><!-- /.navbar-collapse --> </div> </div> <div > <div class="sf-Long-text" ><div class="mobile-header hidden-sm hidden-md hidden-lg"><a href="/"><img class="imageResize" src="/images/librariesprovider48/template-images/24/header-mob.png?sfvrsn=d70cda15_3" alt="Immuno-Oncology Summit 2024" /></a> </div></div> </div> <noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-P76Z87P" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript> <div class="main-content"> <div id="cph1" class="container internal"> <div class="row"> <div class="row" data-sf-element="Row"> <div class="col-sm-9"> <div id="Contentplaceholder1_T39935FB7001_Col00" class="sf_colsIn pad-lr" data-sf-element="Column 1" data-placeholder-label="Column 1"> <div > <div class="sf-Long-text" ><p class="pageTitle">2023 Speaker Interviews</p><div class="row pad-bottom"><div class="col-sm-6"><div class="videoWrapper"><iframe width="560" height="315" src="https://www.youtube.com/embed/79WRDFJvLG0" title="YouTube video player" frameborder="0" allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" allowfullscreen=""></iframe></div></div><br class="hidden-sm hidden-md hidden-lg" /><div class="col-sm-6"><p><b>KEYNOTE PRESENTATION: AI-Based Target and Antibody Discovery for Cancer Immunotherapeutics</b></p><p class="Speaker">Xiaole Shirley Liu, PhD, CEO, GV20 Therapeutics</p></div></div><div><p class="terciary-text">GV20 Therapeutics have computationally extracted hundreds of millions of tumor-infiltrating antibody sequences from tumor RNA-seq profiles. Using AI trained on these tumor-infiltrating antibodies, GV20 can de novo design antibodies against targets without any known antibody sequences against the targets. This approach not only designs antibodies enriched in functional binders and good developability profiles, but also provides insights on target identification and validation.</p></div><p><br clear="all" /></p><div class="row pad-bottom"><div class="col-sm-6"><div class="videoWrapper"><iframe width="560" height="315" src="https://www.youtube.com/embed/kEzx81g0gBg" title="YouTube video player" frameborder="0" allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" allowfullscreen=""></iframe></div></div><br class="hidden-sm hidden-md hidden-lg" /><div class="col-sm-6"><p><b><a href="/AI-Cancer-Immunotherapy#JohnCatanzaro" data-sf-ec-immutable="">AI, ML, and DL in Molecular Design and Immunoediting Mechanisms and Implications in Individualized Cancer Therapeutics</a></b></p><p class="Speaker">John A. Catanzaro, PhD, Founder & CEO, Neo7Bioscience, Inc.</p></div></div><div><p class="terciary-text">In cancer immunotherapy, AI, ML, and DL are critical in developing precision-based targeted therapeutics and personalized molecular engineering. The complex cell signaling pathways, protein-to-protein interactions (PPI), cancer hallmark expressions, and the integral relationship of the differential multi-omic data expression necessitate a high confidence ranking, mapping, modeling, and selection architecture in developing small molecules, peptides, and peptide oligonucleotide conjugates. Cancer immunoediting is a molecular control process requiring a robust multi-omic design pipeline. The key features to consider in creating a design are immunoediting in cancer (elimination, equilibrium, escape) and mechanisms of action (immunosurveillance, immune induction, regulation, augmentation, signal editing, and adaptation.)</p></div><p><br clear="all" /></p></div> </div></div> </div> <div class="col-sm-3"> <div id="Contentplaceholder1_T39935FB7001_Col01" class="sf_colsIn pad-lr" data-sf-element="Column 2" data-placeholder-label="Column 2"><div class='sfContentBlock'><!-- Social Icons --> <br class="hidden-md hidden-lg" /><div class="social-icons"><a target="_blank" title="Outlook" href="/docs/librariesprovider48/ics/24/imx24.ics?sfvrsn=95fcb176_1&download=true"><img src="/images/default-source/social/calendar-gray.png?sfvrsn=91696e36_6" title="Outlook" alt="Outlook" class="social-icon" /></a> <a title="YouTube" href="http://www.youtube.com/CambridgeHealthtech/" target="_blank"><img src="/images/default-source/social/youtube-gray.png?sfvrsn=6bad7b8f_4" title="YouTube" 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