Engenharia de Tecidos

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class="col-sm-12"> <h1 class="font-size-30 fweight-400 color-white">Revista de Medicina Regenerativa </h1> </div> </div> </div> </div> <nav class="navbar navbar-expand-lg bg-navbar navbar-light mega-menu journal-menu topbar-shadow" id="mainNavbar"> <div class="container"> <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbarSupportedContent" aria-controls="navbarSupportedContent" aria-expanded="false" aria-label="Toggle navigation"> <span class="navbar-toggler-icon"></span> </button> <div class="collapse navbar-collapse justify-content-center" id="navbarSupportedContent"> <ul class="navbar-nav mb-auto mb-2 mb-lg-0"> <li class="nav-item"><a class="nav-link" href="https://portuguese.scitechnol.com/journals/regenerative-medicine.html" title="Clique aqui"><i class="fa fa-home" aria-hidden="true"></i></a></li> <li class="nav-item dropdown"> <a class="nav-link dropdown-toggle" href="#" id="navbarDropdown" role="button" data-bs-toggle="dropdown" aria-expanded="false">Instru莽玫es</a> <ul class="dropdown-menu" aria-labelledby="navbarDropdown"> <li><a class="dropdown-item" href="https://portuguese.scitechnol.com/journals/instructionsforauthors-cell-biology-research-therapy.html" title="Clique aqui">Para autor</a></li> <li><a class="dropdown-item" href="https://portuguese.scitechnol.com/journals/ethics-regenerative-medicine.html" title="Clique aqui">Pol铆ticas e 脡tica</a></li> <li><a class="dropdown-item" href="https://portuguese.scitechnol.com/journals/aims-scope-regenerative-medicine.html" title="Clique aqui">Objetivo e escopo</a></li> <li><a class="dropdown-item" href="https://portuguese.scitechnol.com/journals/peer-review-regenerative-medicine.html" title="Clique aqui">Revis茫o por pares</a></li> </ul> </li> <li class="nav-item"><a class="nav-link" href="https://portuguese.scitechnol.com/journals/submitmanuscript-regenerative-medicine.html" title="Clique aqui">Enviar manuscrito</a></li> <li class="nav-item"><a class="nav-link" 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partir da implantação (em vez do transplante) e, portanto, livres de rejeição imunológica. O ponto de partida para qualquer órgão de engenharia de tecidos é a colheita de pequenas quantidades de tecido do futuro receptor do órgão de engenharia de tecidos. Isso pode ser tão pequeno quanto uma biópsia por punch de 2 mm para algumas aplicações. As células da biópsia são cultivadas a partir de explantes ou de uma digestão com colagenase para criar um "banco de células". Estas células são então cultivadas em substratos de colágeno, sob as condições fisiológicas corretas, para formar construções de Engenharia de Tecidos para implantação. O processo é realizado em uma instalação de Cultura de Tecidos para manter um ambiente estéril.</font></font></p> <p style="text-align: justify;"><font style="vertical-align: inherit;"><font style="vertical-align: inherit;">A atividade física e bioquímica celular pode ser potencializada pela adição de fatores de crescimento ou citocinas, também pelo uso de estimulação física. O Monitor de Força de Cultura de Tensão aplica cargas físicas mínimas para estimular a população de células residentes na estrutura de colágeno para a atividade bioquímica e biofísica normalmente associada à organogênese e ao reparo tecidual. Após mais cultura de tecidos sob as condições corretas, as células residentes na construção Tissue Engineered dissolverão a estrutura de colágeno original e secretarão um novo neotecido rico em colágeno, a construção poderá então ser implantada de volta no paciente de quem as células foram originalmente removidas .</font></font></p> <p style="text-align: justify;"><font style="vertical-align: inherit;"><font style="vertical-align: inherit;">A engenharia de tecidos tem um potencial de mercado significativo e o investimento financeiro continua em ritmo acelerado. Um inquérito realizado em 1997 revelou que, só nesse ano, as despesas de I&D directamente ligadas a projectos empresariais de engenharia de tecidos foram de cerca de 0,5 mil milhões de dólares, com uma taxa de crescimento de cerca de 22% ao ano. Isto demonstra o interesse sustentado nesta área, impulsionado em parte pelos resultados positivos relativos a produtos e processos específicos em ambientes clínicos. Os avanços técnicos nos diversos componentes da indústria contribuirão para o crescimento do mercado. Um componente é a disponibilidade de biomateriais que atuam como suportes para reparo e reconstrução de tecidos, ou para a deposição de tecidos e células projetados antes da implantação. Uma quantidade crescente de P&D é direcionada para abordar as propriedades desses andaimes com o objetivo de criar materiais que tenham os perfis funcionais desejados para diversas aplicações.</font></font></p> </div> </div>  <div class="col-xs-12 col-md-3"> <div class="divider-v4 divider-v4-left-double bg-color-white padding-10 margin-b-10"> <h2 class="divider-v4-title">Explore a Ci锚nciaTecnologia</h2> <div> <ul class="list-unstyled angle-right"> <li class="color-base"><a href="https://portuguese.scitechnol.com/author-guidelines.html" title="Clique aqui"> Diretrizes para Autores</a></li> <li class="color-base"><a href="https://portuguese.scitechnol.com/reviewer-guidelines.html" title="Clique aqui"> Diretrizes para revisores</a></li> <li class="color-base"><a href="https://portuguese.scitechnol.com/scitechnol-associations-indexing.html" title="Clique aqui"> Associa莽玫es</a></li> <li class="color-base"><a href="https://portuguese.scitechnol.com/submitmanuscript.html" title="Clique aqui"> 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