CINXE.COM

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href="/science/applications/research-areas/post-mortem-brain-tissue">Post-mortem Brain Tissue</a></li></ul></div></div></div><div class="row menu__blocks"><div class="col-lg-3 col-md-3 col-sm-3 col-xs-12 menu-col"><div class="sec-title">Other</div> <span class="sectitle-span">+</span><ul><li><a href="/science/applications/research-solutions/circular-rna">Circular RNA</a></li><li><a href="/science/applications/research-solutions/gene-fusions">Gene Fusions</a></li><li><a href="/science/applications/research-solutions/ngsht-transcriptomic-validation-rna-seq">HT Transcript Validation</a></li><li><a href="/science/applications/research-solutions/long-noncoding-rna">Long Non-coding RNA</a></li><li><a href="/science/applications/research-solutions/ngsht-transcriptomic-validation-rna-seq">RNAseq Validation</a></li><li><a href="/science/applications/research-solutions/single-cell-analysis">Single Cell Analysis</a></li><li><a href="/science/applications/research-solutions/splice-variant">Splice Variant</a></li><li><a href="/science/applications/research-solutions/mirna">miRNA</a></li></ul></div><div class="col-lg-3 col-md-3 col-sm-3 col-xs-12 menu-col"><div class="sec-title">RNA & Protein</div> <span class="sectitle-span">+</span><ul><li><a href="/science/applications/research-solutions/antibody-challenges-and-validation">Antibody Challenges</a></li><li><a href="/science/applications/research-solutions/dual-ish-and-ihc">Dual ISH + IHC Methods</a></li><li><a href="/science/applications/research-solutions/no-antibodies-available">No Antibodies</a></li><li><a href="/science/applications/research-solutions/ish-and-ihc-complementary">RNA & Protein Analysis</a></li></ul></div><div class="col-lg-3 col-md-3 col-sm-3 col-xs-12 menu-col"><div class="sec-title">Customer Innovations</div> <span class="sectitle-span">+</span><ul><li><a href="/innovations-rnascope">Dual RNA+DNA ISH</a></li><li><a href="/innovations-rnascope">Very old FFPE ISH</a></li><li><a href="/innovations-rnascope">Wholemount ISH</a></li></ul></div><div class="col-lg-3 col-md-3 col-sm-3 col-xs-12 menu-col"><div class="sec-title">Animal Models</div> <span class="sectitle-span">+</span><ul><li><a href="/science/applications/animal-models/virtually-any-species">Any Species</a></li><li><a href="/science/applications/animal-models/mouse-model">Mouse Model</a></li><li><a href="/science/applications/animal-models/preclinical-safety-assessment">Preclincal Safety</a></li></ul></div></div></div></div></li><li class="level0 technology"> <a href="/science/technology-overview" class="level0">Technology</a> <span class="level0 visible-xs">+</span><div class="menu-content"><div class="container"><div class="row menu__blocks"><div class="col-lg-3 col-md-3 col-sm-3 col-xs-12 menu-col"><div class="sec-title"><a href="/science/technology-overview">Overview</a></div> <span class="sectitle-span">+</span><ul><li><a href="/science/how-it-works">How it Works</a></li><li><a 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region-content"><div id="block-system-main" class="block block-system clearfix"><div class="content"> <script src="//info.bio-techne.com/js/forms2/js/forms2.min.js"></script> <div id="node-20219" class="node node-marketing-overview node-promoted" about="/pas" typeof="sioc:Item foaf:Document"><div class="nav-tab-container"><ul class="nav nav-tabs page-tabs" id="myTab"><li class="active"><a href="/pas" class="active">Our services</a></li><li><a href="/new-multiomics-services">NEW Multiomics Services</a></li><li><a href="/biomarker-assay-development">Biomarker Assay Development</a></li><li><a href="/cell-gene-therapy-services">Cell & Gene Therapy Services</a></li><li><a href="/services/CDx-prototype">Clinical Assay Development</a></li><li><a href="/services/acd-tissue-bank">Tissue Bank & Sample Procurement</a></li><li><a href="/services/quantitative-analysis">Digital Pathology Image Analysis</a></li><li><a href="/services/your-benefits-your-success">Your benefits</a></li><li><a href="/services/how-order">How to Order</a></li><li><a href="/contact-services">Contact Services</a></li></ul></div><div class="tab-content"><div id="profile" class="tab-pane fade in active biopharma"><div class="home_content"><div class="biopharma-content"><div class="biopharma-title">Expert ISH and Image Analysis Services</div><p><iframe allow="accelerometer; clipboard-write; encrypted-media; gyroscope; picture-in-picture" allowfullscreen="" frameborder="0" height="315" src="https://www.youtube.com/embed/260-jMUCWdE" title="ACD Professional Assay Services" width="560"></iframe></p><p>Professional Assay Services (PAS) provides GCLP-compliant RNAscope, BaseScope™, miRNAscope™ <em>in situ</em> hybridization (ISH) assay services to support clinical and pre-clinical studies for our academic and biopharma partners. We provide end-to-end solutions from sample procurement to ISH staining to image analysis and reporting. Researchers who partner with Professional Assay Services will receive access to the most specialized and technically experienced RNAscope services of any CRO, provided by an expert multi-disciplinary team that includes PhD scientists and MDs, who serve our clients as technical experts, image analysis specialists and board-certified pathologists, spanning a broad array of scientific disciplines. With direct access to the developers of the technology, the PAS team provides unparalleled expertise in Bio-Techne's ISH platforms and delivers fast, high-quality data designed to meet your study objectives and timelines.</p><div class="row review"><h2>Flyer</h2><div class="col-md-6"><img src="/sites/default/files/MK51_184RevA_Power_Through_with_RNAscope_PAS.jpg" /></div><div class="col-md-6"><h3>Power Your Next Breakthrough from Target Validation to Clinical Development with RNAscope™ Professional Highlights Assay Services</h3><div class="rteindent1 download-pdf"><p><a class="down-pdf-btn" href="/system/files_force/MK51_184RevA_Power_Through_with_RNAscope_PAS.pdf?download=1" style="min-width:265px;">Download Flyer</a></p></div><p class="rteindent1"><a class="learn-more" href="https://info.bio-techne.com/WEB-ACD-2023-07-PAS-Lead-Capture-Assay-Services-7398_01-LP-Main.html" style="min-width:265px;" target="_blank">Request a Free PAS Project<br />Consultation - Click Here</a></p></div><div class="clear"> </div></div><h2>Why Choose PAS as your ISH and Multiomic service provider?</h2><ul><li>A decade of experience as a service provider, delivering 15,000+ stained slides per year</li><li>An established history of servicing 28 of the 30 global pharmaceutical companies as well as dozens of cell and gene therapy biotech companies</li><li>Ph.D. level scientists and MD pathologists who are specialized experts and provide scientific consultation for study design and data interpretation</li></ul><h2>What We Offer: Tissue-Based Expression Analysis</h2><ul><li><span style="color:#008080;"><strong>Target validation</strong>.</span> Screen and validate candidate targets by assessing target expression levels in drug-treated versus naïve samples or disease vs normal tissues</li><li><span style="color:#008080;"><strong>Biomarker assay development</strong>.</span> Evaluate candidate biomarker expression and establish assay performance and dynamic range using bioanalytical method validation guidelines</li><li><span style="color:#008080;"><strong>AAV biodistribution</strong></span>. Profile the spatial distribution of AAV vector together with genetically modified transgenes to assess biodistribution and safety</li><li><span style="color:#008080;"><strong>CAR/TCR biodistribution and function</strong>.</span> Visualize the biodistribution of CAR T or TCR T cells within the tumor microenvironment and assess functionality with co-detection of immune cell markers and/or markers of activation</li><li><span style="color:#008080;"><strong>Safety/toxicology tissue screening</strong>.</span> Single-molecule detection for high sensitivity screening of normal tissues for pre-clinical ADME and safety assessment</li><li><span style="color:#008080;"><strong>CDx assay development</strong></span>. Partner with ACD to support the assay prototype development, proof of concept and validation steps of your RNAscope CDx assay</li></ul></div><div class="quality-results"><div class="biopharma-title"></div></div><div class="hexa-section"><div class="six-section"><div class="list" id="list6" target="6"> <img class="image" src="/sites/all/themes/acd/images/services/6-blue-line.png" alt=""> <img class="h-image" src="/sites/all/themes/acd/images/services/6-blue-fill.png" alt=""></div><div class="list" id="list1" target="1"> <img class="image" src="/sites/all/themes/acd/images/services/1-blue-line.png" alt=""> <img class="h-image" src="/sites/all/themes/acd/images/services/1-blue-fill.png" alt=""></div><div class="list" id="list2" target="2"> <img class="image" src="/sites/all/themes/acd/images/services/2-blue-line.png" alt=""> <img class="h-image" src="/sites/all/themes/acd/images/services/2-blue-fill.png" alt=""></div><div class="list" id="list3" target="3"> <img class="image" src="/sites/all/themes/acd/images/services/3-blue-line.png" alt=""> <img class="h-image" src="/sites/all/themes/acd/images/services/3-blue-fill.png" alt=""></div><div class="list" id="list4" target="4"> <img class="image" src="/sites/all/themes/acd/images/services/4-blue-line.png" alt=""> <img class="h-image" src="/sites/all/themes/acd/images/services/4-blue-fill.png" alt=""></div><div class="list" id="list5" target="5"> <img class="image" src="/sites/all/themes/acd/images/services/5-blue-line.png" alt=""> <img class="h-image" src="/sites/all/themes/acd/images/services/5-blue-fill.png" alt=""></div></div><div class="overlay-popup"><div id="popuplocal1" style="display: none;" class="hex_popup"><div class="close-popup"><img src="/sites/all/themes/acd/images/services/icon-close.png" alt=""></div><div class="details"><p>The Tissue bank is a set of pre-sourced, pre-qualified samples and we can also help procure samples from tissue vendors</p></div></div><div id="popuplocal2" style="display: none;" class="hex_popup"><div class="close-popup"><img src="/sites/all/themes/acd/images/services/icon-close.png" alt=""></div><div class="details"><p>Our team can coordinate embedding and tissue sectioning for faster turnaround</p></div></div><div id="popuplocal3" style="display: none;" class="hex_popup"><div class="close-popup"><img src="/sites/all/themes/acd/images/services/icon-close.png" alt=""></div><div class="details"><p>Providing RNAscope, BaseScope, miRNAscope ISH and ISH-IHC, ISH-IF Staining</p></div></div><div id="popuplocal4" style="display: none;" class="hex_popup"><div class="close-popup"><img src="/sites/all/themes/acd/images/services/icon-close.png" alt=""></div><div class="details"><p>We offer semi-quantitative scoring, pathologist H-scoring and quantitative software-based analysis. <a href="/services/quantitative-analysis">Click here</a> to learn more</p></div></div><div id="popuplocal5" style="display: none;" class="hex_popup"><div class="close-popup"><img src="/sites/all/themes/acd/images/services/icon-close.png" alt=""></div><div class="details"><p>We offer data review by our board-certified pathologists for image and expression analysis. <a href="/services/quantitative-analysis">Click here</a> to learn more</p></div></div><div id="popuplocal6" style="display: none;" class="hex_popup"><div class="close-popup"><img src="/sites/all/themes/acd/images/services/icon-close.png" alt=""></div><div class="details"><p>A complete summary report is an option for every project</p></div></div></div></div> <script type="text/javascript"> jQuery(document).ready(function(){ jQuery('.six-section .list').mouseover(function() { jQuery('.hex_popup').hide(); jQuery('#popuplocal' + jQuery(this).attr('target')).show(); }); jQuery('.six-section .list').mouseout(function() { jQuery('.hex_popup').hide(); }); jQuery('.overlay-popup .close-popup').click(function(){ jQuery('.hex_popup').hide(); }) }); </script> <div class="services-cont"><div class="row services-cont-row"></div></div><div class="explore-wrap bottom"><div class="explore"><div class="explore-title"><p>We are supporting a broad range of pre-clinical and clinical applications in every therapeutic area including:</p></div><div class="row"><div class="col-lg-3 col-md-3 col-sm-6 col-xs-12 models-wrap"> <a href="https://acdbio.com/science/applications/research-areas/cell-therapy" class="models"> <span class="model-name">Cell therapy</span> <span class="model-image"> <img src="/sites/default/files/cell-theraphy-icon.png" width="65" height="65" alt=""> </span> </a></div><div class="col-lg-3 col-md-3 col-sm-6 col-xs-12 models-wrap"> <a href="https://acdbio.com/co-detection-of-mrna-and-protein" class="models"> <span class="model-name">RNA-Protein Co-detection</span> <span class="model-image"> <img src="/sites/default/files/Rna-Protein-icon.png" width="65" height="65" alt=""> </span> </a></div><div class="col-lg-3 col-md-3 col-sm-6 col-xs-12 models-wrap"> <a href="https://acdbio.com/companion-diagnostics" class="models"> <span class="model-name">Companion Diagnostics</span> <span class="model-image"> <img src="/sites/default/files/companion-icon.png" width="65" height="65" alt=""> </span> </a></div><div class="col-lg-3 col-md-3 col-sm-6 col-xs-12 models-wrap"> <a href="https://acdbio.com/science/applications/animal-models/preclinical-safety-assessment" class="models"> <span class="model-name">Drug Safety Testing</span> <span class="model-image"> <img src="/sites/all/themes/acd/images/services/img6.jpg" width="65" height="65" alt=""> </span> </a></div><div class="col-lg-3 col-md-3 col-sm-6 col-xs-12 models-wrap"> <a href="https://acdbio.com/science/applications/research-areas/gene-therapy" class="models"> <span class="model-name">Gene Therapy</span> <span class="model-image"> <img src="/sites/default/files/gene_therapy.jpg" width="65" height="65" alt=""> </span> </a></div><div class="col-lg-3 col-md-3 col-sm-6 col-xs-12 models-wrap"> <a href="https://acdbio.com/science/applications/research-solutions/validates-ht-transcriptomic-rna-seq" class="models"> <span class="model-name">Biomarker Dev & validation</span> <span class="model-image"> <img src="/sites/default/files/biomarker.jpg" width="65" height="65" alt=""> </span> </a></div><div class="col-lg-3 col-md-3 col-sm-6 col-xs-12 models-wrap"> <a href="https://acdbio.com/science/applications/research-areas/cancer" class="models"> <span class="model-name">Cancer</span> <span class="model-image"> <img src="/sites/default/files/cancer_0.jpg" width="65" height="65" alt=""> </span> </a></div><div class="col-lg-3 col-md-3 col-sm-6 col-xs-12 models-wrap"> <a href="https://acdbio.com/science/applications/research-areas/immuno-oncology" class="models"> <span class="model-name">Immuno-Oncology</span> <span class="model-image"> <img src="/sites/default/files/immuno.jpg" width="65" height="65" alt=""> </span> </a></div><div class="col-lg-3 col-md-3 col-sm-6 col-xs-12 models-wrap"> <a href="https://acdbio.com/science/applications/research-areas/neuroscience" class="models"> <span class="model-name">Neuroscience</span> <span class="model-image"> <img src="/sites/default/files/Neuroscience.jpg" width="65" height="65" alt=""> </span> </a></div><div class="col-lg-3 col-md-3 col-sm-6 col-xs-12 models-wrap"> <a href="https://acdbio.com/science/applications" class="models"> <span class="model-name">Other applications</span> <span class="model-image"> <img src="/sites/default/files/inflamation_0.jpg" width="65" height="65" alt=""> </span> </a></div></div></div></div><div class="biopharma-content"><div class="profile-bottom publication"><h2>Resources</h2><div class="show-hide"><div class="r-show"><h3>Publications</h3><ul><li><p><a href="https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(20)30210-X?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS266637912030210X%3Fshowall%3Dtrue#secsectitle0020">Development and Preliminary Clinical Activity of PD-1-Guided CTLA-4 Blocking Bispecific DART Molecule</a></p><p>Berezhnoy A, Sumrow BJ, Stahl K, Shah K, Liu D, Li J, Hao SS, De Costa A, Kaul S, Bendell J, Cote GM, Luke JJ, Sanborn RE, Sharma MR, Chen F, Li H, Diedrich G, Bonvini E, Moore PA. Cell Rep Med. 2020 Dec 22</p></li><li><p><a href="https://www.cell.com/molecular-therapy-family/methods/fulltext/S2329-0501(20)30151-0?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2329050120301510%3Fshowall%3Dtrue">AAV2/6 Gene Therapy in a Murine Model of Fabry Disease Results in Supraphysiological Enzyme Activity and Effective Substrate Reduction.</a></p><p>Yasuda M, Huston MW, Pagant S, Gan L, St Martin S, Sproul S, Richards D, Ballaron S, Hettini K, Ledeboer A, Falese L, Cao L, Lu Y, Holmes MC, Meyer K, Desnick RJ, Wechsler T. Mol Ther Methods Clin Dev. 2020 Jul 9</p></li><li><p><a href="https://jitc.bmj.com/content/7/1/276">Systemic and local immunity following adoptive transfer of NY-ESO-1 SPEAR T cells in synovial sarcoma.</a></p><p>Ramachandran, I., Lowther, D. E., Dryer-Minnerly, R., Wang, R., Fayngerts, S., Nunez, D., Betts, G., Bath, N., Tipping, A. J., Melchiori, L., Navenot, J. M., Glod, J., Mackall, C. L., D'Angelo, S. P., Araujo, D. M., Chow, W. A., Demetri, G. D., Druta, M., Van Tine, B. A., Grupp, S. A., … Basu, S. J Immunother Cancer. 2019 Oct 24</p></li><li><p><a href="https://www.frontiersin.org/articles/10.3389/fnins.2019.00281/full">GPR139 and Dopamine D2 Receptor Co-express in the Same Cells of the Brain and May Functionally Interact</a></p><p>Wang L, Lee G, Kuei C, Yao X, Harrington A, Bonaventure P, Lovenberg TW, Liu C. Front. Neurosci., 2019 March 26</p></li></ul></div><div class="r-hide"><ul><li><p><a href="https://www.nature.com/articles/nm.4393">The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL</a></p><p>Emmerson PJ, Wang F, Du Y, Liu Q, Pickard RT, Gonciarz MD, Coskun T, Hamang MJ, Sindelar DK, Ballman KK, Foltz LA, Muppidi A, Alsina-Fernandez J, Barnard GC, Tang JX, Liu X, Mao X, Siegel R, Sloan JH, Mitchell PJ, Zhang BB, Gimeno RE, Shan B, Wu X. Nature Medicine . 2017 August 28</p></li><li><p><a href="https://www.cell.com/molecular-therapy-family/nucleic-acids/fulltext/S2162-2531(17)30156-7">Translation of angiotensin converting enzyme 2 (ACE2) upon liver and lung targeted delivery of optimized chemically modified mRNA.</a></p><p>Eva Schrom, Maja Huber, Manish Aneja, Christian Dohmen, Daniela Emrich, Johannes Geiger, Günther Hasenpusch, Annika Herrmann-Janson, Verena Kretzschmann, Olga Mykhailyk, Tamara Pasewald, Prajakta Oak, Anne Hilgendorff, Dirk Wohlleber, Heinz-Gerd Hoymann, Dirk Schaudien, Christian Plank, Carsten Rudolph, Rebekka Kubisch-Dohmen. Mol Ther Nuc Acids. 2017 May 05</p></li><li><p><a href="https://pubmed.ncbi.nlm.nih.gov/27270421/">Integrated genomic analysis of colorectal cancer progression reveals activation of EGFR through demethylation of the EREG promoter.</a></p><p>Qu, X., Sandmann, T., Frierson, H., Jr, Fu, L., Fuentes, E., Walter, K., Okrah, K., Rumpel, C., Moskaluk, C., Lu, S., Wang, Y., Bourgon, R., Penuel, E., Pirzkall, A., Amler, L., Lackner, M. R., Tabernero, J., Hampton, G. M., & Kabbarah, O. Oncogene, 2016 Dec 5</p></li><li><p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838384/">Functional annotation of the vlinc class of non-coding RNAs using systems biology approach.</a></p><p>St Laurent, G., Vyatkin, Y., Antonets, D., Ri, M., Qi, Y., Saik, O., Shtokalo, D., de Hoon, M. J., Kawaji, H., Itoh, M., Lassmann, T., Arner, E., Forrest, A. R., FANTOM consortium, Nicolas, E., McCaffrey, T. A., Carninci, P., Hayashizaki, Y., Wahlestedt, C., & Kapranov, P. Nucleic acids research. 2016 Apr 20</p></li><li><p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919276/">Overexpression of the Long Non-coding RNA SChLAP1 Independently Predicts Lethal Prostate Cancer</a></p><p>Mehra R, Udager AM, Ahearn TU, Cao X, Feng FY, Loda M, Petimar JS, Kantoff P, Mucci LA, Chinnaiyan AM. Eur Urol. 2016 Oct.</p></li><li><p><a href="https://pubmed.ncbi.nlm.nih.gov/26259677/">FGFR1 and FGFR2 in Fibrolamellar Carcinoma</a></p><p>Graham RP, Garcia JJ, Greipp PT, Barr Fritcher EG, Kipp BR, Torbenson MS. FGFR1 and FGFR2 in fibrolamellar carcinoma. Histopathology. 2016 Apr</p></li><li><p><a href="https://www.nature.com/articles/nature15715">Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung</a></p><p>Lafkas D, Shelton A, Chiu C, de Leon Boenig G, Chen Y, Stawicki SS, Siltanen C, Reichelt M, Zhou M, Wu X, Eastham-Anderson J, Moore H, Roose-Girma M, Chinn Y, Hang JQ, Warming S, Egen J, Lee WP, Austin C, Wu Y, Payandeh J, Lowe JB, Siebel CW. Nature. 2015 Dec 3;</p></li><li><p><a href="https://www.nature.com/articles/modpathol20154">DNAJB1-PRKACA is specific for fibrolamellar carcinoma.</a></p><p>Graham RP, Jin L, Knutson DL, Kloft-Nelson SM, Greipp PT, Waldburger N, Roessler S, Longerich T, Roberts LR, Oliveira AM, Halling KC, Schirmacher P, Torbenson MS. Mod Pathol. 2015 Jun</p></li><li><p><a href="http://www.ncbi.nlm.nih.gov/pubmed/26222558">Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor.</a></p><p>Tap WD, Wainberg ZA, Anthony SP, Ibrahim PN, Zhang C, Healey JH, Chmielowski B, Staddon AP, Cohn AL, Shapiro GI, Keedy VL, Singh AS, Puzanov I, Kwak EL, Wagner AJ, Von Hoff DD, Weiss GJ, Ramanathan RK, Zhang J, Habets G, Zhang Y, Burton EA, Visor G, Sanftner L, Severson P, Nguyen H, Kim MJ, Marimuthu A, Tsang G, Shellooe R, Gee C, West BL, Hirth P, Nolop K, van de Rijn M, Hsu HH, Peterfy C, Lin PS, Tong-Starksen S, Bollag G. N Engl J Med. 2015 Jul 30;373(5):428-37</p></li><li><p><a href="http://www.ncbi.nlm.nih.gov/pubmed/25838397">Upregulation of Periostin and Reactive Stroma Is Associated with Primary Chemoresistance and Predicts Clinical Outcomes in Epithelial Ovarian Cancer.</a></p><p>Ryner L, Guan Y, Firestein R, Xiao Y, Choi Y, Rabe C, Lu S, Fuentes E, Huw LY, Lackner MR, Fu L, Amler LC, Bais C, Wang Y. Clin Cancer Res. 2015 Jul 1</p></li><li><p><a href="http://www.ncbi.nlm.nih.gov/pubmed/26050928">Transcriptome-wide Analysis Reveals Hallmarks of Human Intestine Development and Maturation In Vitro and In Vivo.</a></p><p>Finkbeiner SR, Hill DR, Altheim CH, Dedhia PH, Taylor MJ, Tsai YH, Chin AM, Mahe MM, Watson CL, Freeman JJ, Nattiv R, Thomson M, Klein OD, Shroyer NF, Helmrath MA, Teitelbaum DH, Dempsey PJ, Spence JR. Stem Cell Reports. 2015 Jun 3</p></li><li><p><a href="http://www.ncbi.nlm.nih.gov/pubmed/25971554">Expression of folate receptors alpha and beta in normal and cancerous gynecologic tissues: correlation of expression of the beta isoform with macrophage markers.</a></p><p>O'Shannessy DJ, Somers EB, Wang LC, Wang H, Hsu R. J Ovarian Res. 2015 May 14</p></li></ul></div></div><div class="row review app-appendix"><h3>PAS Brochure</h3><div class="col-md-4"><img src="/sites/default/files/PAS-Brochure.jpg" style="max-width: 100%;"></div><div class="col-md-8 download-pdf"><h3>Download Professional Assay Services Brochure</h3><div class="marketo-container"> <a class="down-pdf-btn" href="/system/files_force/PAS-Brochure.pdf?download=1">Download Brochure</a></div></div><div class="clear"> </div></div></div></div></div></div></div></div> <script type="text/javascript"> jQuery(document).ready(function($) { $('.marketo-popup').click(function(event){ event.preventDefault(); console.log("mrktoform"); var mrktContainer = $(this).parent().parent(); var mrktoform = mrktContainer.find("form").attr('rel'); console.log(mrktoform); MktoForms2.loadForm("//info.bio-techne.com", "584-XSF-168", mrktoform, function (form){ MktoForms2.lightbox(form).show(); mrktContainer.append('<form id="mktoForm_'+mrktoform+'" rel="'+mrktoform+'" 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