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Innovation and Research | UCSF Institute for Global Health Sciences
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</div> </div> </header> <div id="content" class="site-content container"> <div id="primary" class="content-area"> <main id="main" class="site-main"> <article id="post-1825" class="post-1825 page type-page status-publish has-post-thumbnail hentry page_category-area-of-expertise"> <header class="entry-header basic-hero"> <div class="container"> <h1>Innovation and Research</h1> </div> <div class="background-image"> <img src="https://globalhealthsciences.ucsf.edu/wp-content/plugins/phastpress/phast.php?service=images&src=https%3A%2F%2Fglobalhealthsciences.ucsf.edu%2Fwp-content%2Fuploads%2F2023%2F10%2FOurWork.jpg&cacheMarker=1697067207-487095&token=29487da5df74f8ca" srcset="https://globalhealthsciences.ucsf.edu/wp-content/plugins/phastpress/phast.php?service=images&src=https%3A%2F%2Fglobalhealthsciences.ucsf.edu%2Fwp-content%2Fuploads%2F2023%2F10%2FOurWork.jpg&cacheMarker=1697067207-487095&token=29487da5df74f8ca 1650w, 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current_page_parent"><a href="https://globalhealthsciences.ucsf.edu/our-work/areas-of-expertise/">Areas of Expertise</a></li> <li class="page_item page-item-1831 page_item_has_children"><a href="https://globalhealthsciences.ucsf.edu/our-work/health-challenges/">Health Challenges</a></li> <li class="page_item page-item-55"><a href="https://globalhealthsciences.ucsf.edu/our-work/where-we-work/">Where We Work</a></li> <li class="page_item page-item-50"><a href="https://globalhealthsciences.ucsf.edu/our-work/our-impact/">Our Impact</a></li> </ul> </nav> <div class="content-sidebar-wrap"> <div class="entry-content"> <div class="wp-block-columns is-layout-flex wp-container-core-columns-layout-1 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="flex-basis:25%"> <nav class="toc" aria-label="Table of Contents"> <ul> <li><h3 class="widget-title">Areas of Expertise</h3></li> <li><a class="item item--link" href="https://globalhealthsciences.ucsf.edu/our-work/areas-of-expertise/clinical-excellence-and-training/">Clinical Excellence and Training</a></li> <li><a class="item item--link" href="https://globalhealthsciences.ucsf.edu/our-work/areas-of-expertise/data-and-informatics/">Data and Informatics</a></li> <li><a class="item item--link" href="https://globalhealthsciences.ucsf.edu/our-work/areas-of-expertise/innovation-and-research/">Innovation and Research</a></li> <li><a class="item item--link" href="https://globalhealthsciences.ucsf.edu/our-work/areas-of-expertise/policy-advocacy-and-diplomacy/">Policy, Advocacy and Diplomacy</a></li> <li><a class="item item--link" href="https://globalhealthsciences.ucsf.edu/our-work/areas-of-expertise/strengthening-health-systems/">Strengthening Health Systems</a></li> <li><a class="item item--link" href="https://globalhealthsciences.ucsf.edu/our-work/areas-of-expertise/workforce-development/">Workforce Development</a></li> </ul> </nav> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="flex-basis:50%"> <p>Recognizing the potential of technology to revolutionize global health outcomes, IGHS consistently integrates innovative technologies into its research projects. This includes harnessing modern data analysis tools, utilizing mobile technologies for health interventions, and exploring digital solutions to streamline health service delivery. IGHS’s approach focuses on implementation science to ensure that health interventions aren’t just theoretical but practical, effective and scalable in real-world settings. IGHS aims to deliver tangible solutions to pressing global health challenges by melding implementation science with technological innovations.</p> <h2 class="wp-block-heading">Projects</h2> <div class="block block--accordion " id="block-block_f4e1374ec326e7c7bcf4b20845a30c20"> <div class="block__accordions"> <div class="accordion accordion-flush" id="#accordion_block-block_f4e1374ec326e7c7bcf4b20845a30c20"> <div class="accordion-item"> <p class="accordion-header" id="heading1block_f4e1374ec326e7c7bcf4b20845a30c20"> <button class="accordion-button collapsed" type="button" data-bs-toggle="collapse" data-bs-target="#collapse1block_f4e1374ec326e7c7bcf4b20845a30c20" aria-expanded="true" aria-controls="collapse1block_f4e1374ec326e7c7bcf4b20845a30c20"> <span>CHESA Perioperative Health Equity Fellowship</span> </button> </p> <div id="collapse1block_f4e1374ec326e7c7bcf4b20845a30c20" class="accordion-collapse collapse" aria-labelledby="heading1block_f4e1374ec326e7c7bcf4b20845a30c20" data-bs-parent="#accordion_block-block_f4e1374ec326e7c7bcf4b20845a30c20"> <div class="accordion-body"> <p>The <span class="scayt-misspell-word" data-scayt-word="CHESA" data-wsc-lang="en_US" data-wsc-id="lr5klnlit9l84wqus">CHESA</span> Fellowship is a one-year, part-time, <span class="scayt-misspell-word" data-scayt-word="non-ACGME" data-wsc-lang="en_US" data-wsc-id="lr5klnlha2g4t1eph">non-ACGME</span> fellowship for individuals committed to building careers focused on advancing health equity in perioperative care. The program leverages UCSF resources and expertise to foster the next generation of global surgery and anesthesia leaders who use research, education and advocacy to address disparities in perioperative care.</p> <p><strong>Country of activity</strong><br /> The program is administered in the United States. Fellows are from Haiti, Liberia, Nigeria, Uganda, Rwanda, Burundi, Mozambique, Tanzania, Kenya, Ethiopia, Jordan, Romania, and the United States.</p> <p><strong>IGHS Center</strong><br /> <a href="https://globalhealthsciences.ucsf.edu/about-us/our-centers/center-for-health-equity-in-surgery-and-anesthesia/" data-cke-saved-href="https://globalhealthsciences.ucsf.edu/about-us/our-centers/center-for-health-equity-in-surgery-and-anesthesia/">Center for Health Equity in Surgery and Anesthesia</a></p> <p><strong>Contact</strong><br /> <span class="scayt-misspell-word" data-scayt-word="Doruk" data-wsc-lang="en_US" data-wsc-id="lr5klnocf5gj0t8qg">Doruk</span> <span class="scayt-misspell-word" data-scayt-word="Ozgediz" data-wsc-lang="en_US" data-wsc-id="lr5klnocg32mxooa2">Ozgediz</span>, MD, <span class="scayt-misspell-word" data-scayt-word="MSc" data-wsc-lang="en_US" data-wsc-id="lr5klnobvucyhtidk">MSc</span> <a href="mailto:doruk.ozgediz@ucsf.edu" data-cke-saved-href="mailto:doruk.ozgediz@ucsf.edu">doruk.ozgediz@ucsf.edu</a><br /> Lia Jacobson, MD <a href="mailto:lia.jacobson@ucsf.edu" data-cke-saved-href="mailto:lia.jacobson@ucsf.edu">lia.jacobson@ucsf.edu</a><br /> Sriranjani Padmanabhan, MD <a href="mailto:sriranjani.padmanabhan@ucsf.edu" data-cke-saved-href="mailto:sriranjani.padmanabhan@ucsf.edu">sriranjani.padmanabhan@ucsf.edu</a></p> <p><strong>More information</strong><br /> <a href="https://globalsurgery.org/fellowships/the-chesa-fellowship/" data-cke-saved-href="https://globalsurgery.org/fellowships/the-chesa-fellowship/">The <span class="scayt-misspell-word" data-scayt-word="CHESA" data-wsc-lang="en_US" data-wsc-id="lr5klnwaalg2k7zz1">CHESA</span> Fellowship</a></p> </div> </div> </div> <div class="accordion-item"> <p class="accordion-header" id="heading2block_f4e1374ec326e7c7bcf4b20845a30c20"> <button class="accordion-button collapsed" type="button" data-bs-toggle="collapse" data-bs-target="#collapse2block_f4e1374ec326e7c7bcf4b20845a30c20" aria-expanded="true" aria-controls="collapse2block_f4e1374ec326e7c7bcf4b20845a30c20"> <span>Collective for Resilient Societies and Technology (CREST) Initiative</span> </button> </p> <div id="collapse2block_f4e1374ec326e7c7bcf4b20845a30c20" class="accordion-collapse collapse" aria-labelledby="heading2block_f4e1374ec326e7c7bcf4b20845a30c20" data-bs-parent="#accordion_block-block_f4e1374ec326e7c7bcf4b20845a30c20"> <div class="accordion-body"> <p>The CREST Initiative aims to be a beacon of interdisciplinary research, education and outreach in pioneering initiatives that harness technology to fortify societies against present and future adversities, such as pandemics and human-caused disasters.</p> <p><strong>Country of activity</strong><br /> United States</p> <p><strong>Partners</strong><br /> Positive and Adverse Childhood Experiences (PACEs) Connection, Resilient Collective</p> <p><strong>Funders</strong><br /> Centers for Disease Control and Prevention, National Science Foundation, UCSF Resource Allocation Program</p> <p><strong>IGHS Center</strong><br /> <a href="https://globalhealthsciences.ucsf.edu/about-us/our-centers/center-for-pandemic-preparedness-and-response/" data-cke-saved-href="https://globalhealthsciences.ucsf.edu/about-us/our-centers/center-for-pandemic-preparedness-and-response/">Center for Pandemic Preparedness and Response</a></p> <p><strong>Contact</strong><br /> Mohsen Malekinejad, MD, DrPH <a href="mailto:mmalekinejad@ucsf.edu" data-cke-saved-href="mailto:mmalekinejad@ucsf.edu">mmalekinejad@ucsf.edu</a></p> <p><strong>More information</strong><br /> <a href="https://globalhealthsciences.ucsf.edu/our-work/areas-of-expertise/data-and-informatics/collective-for-resilient-societies-and-technology-crest-initiative/" data-cke-saved-href="https://globalhealthsciences.ucsf.edu/our-work/areas-of-expertise/data-and-informatics/collective-for-resilient-societies-and-technology-crest-initiative/">Collective for Resilient Societies and Technology (CREST) Initiative</a></p> </div> </div> </div> <div class="accordion-item"> <p class="accordion-header" id="heading3block_f4e1374ec326e7c7bcf4b20845a30c20"> <button class="accordion-button collapsed" type="button" data-bs-toggle="collapse" data-bs-target="#collapse3block_f4e1374ec326e7c7bcf4b20845a30c20" aria-expanded="true" aria-controls="collapse3block_f4e1374ec326e7c7bcf4b20845a30c20"> <span>Combating Unequal Treatment in Healthcare Through Virtual Awareness and Training in Empathy (CULTIVATE</span> </button> </p> <div id="collapse3block_f4e1374ec326e7c7bcf4b20845a30c20" class="accordion-collapse collapse" aria-labelledby="heading3block_f4e1374ec326e7c7bcf4b20845a30c20" data-bs-parent="#accordion_block-block_f4e1374ec326e7c7bcf4b20845a30c20"> <div class="accordion-body"> <p>CULTIVATE uses virtual reality (VR) to deliver diversity, equity, and inclusion training to health care providers. This project aims to understand if changes in medical education enhanced by VR will improve health access, quality of care, and health outcomes of individuals who are Black, Indigenous, and People of Color.</p> <p><strong>Country of activity</strong><br /> United States</p> <p><strong>Funder</strong><br /> Genentech</p> <p><strong>IGHS Center</strong><br /> <a href="https://globalhealthsciences.ucsf.edu/about-us/our-centers/center-for-pandemic-preparedness-and-response/">Center for Pandemic Preparedness and Response</a></p> <p><strong>Contact</strong><br /> Nova Wilson, MPH <a href="mailto:nova.wilson@ucsf.edu">nova.wilson@ucsf.edu</a></p> <p><strong>More information</strong><br /> <a href="https://pandemic.ucsf.edu/cultivate">CULTIVATE</a></p> </div> </div> </div> <div class="accordion-item"> <p class="accordion-header" id="heading4block_f4e1374ec326e7c7bcf4b20845a30c20"> <button class="accordion-button collapsed" type="button" data-bs-toggle="collapse" data-bs-target="#collapse4block_f4e1374ec326e7c7bcf4b20845a30c20" aria-expanded="true" aria-controls="collapse4block_f4e1374ec326e7c7bcf4b20845a30c20"> <span>Community-based trials of drugs and vector control interventions to reduce malaria transmission</span> </button> </p> <div id="collapse4block_f4e1374ec326e7c7bcf4b20845a30c20" class="accordion-collapse collapse" aria-labelledby="heading4block_f4e1374ec326e7c7bcf4b20845a30c20" data-bs-parent="#accordion_block-block_f4e1374ec326e7c7bcf4b20845a30c20"> <div class="accordion-body"> <p>The Malaria Elimination Initiative leads two randomized controlled trials to reduce malaria transmission. CHILD (Child Health and Infection with Low Density) Malaria in Tanzania assesses the health and socioeconomic impacts of testing and treating low-density malaria infections among children. FLAME (FocaL Mass Drug Administration for Vivax Malaria Elimination) in Peru evaluates the efficacy of focal mass drug administration in reducing malaria transmission.</p> <p><strong>Countries of activity</strong><br /> Tanzania, Peru</p> <p><strong>Partners</strong><br /> Universidad Peruana Cayetano Heredia, Ifakara Health Institute, PATH, Stanford University, Swiss Tropical and Public Health Institute</p> <p><strong>Funders</strong><br /> National Institutes of Health, National Institute of Allergy and Infectious Diseases</p> <p><strong>IGHS Center</strong><br /> <a href="https://globalhealthsciences.ucsf.edu/about-us/our-centers/center-for-global-infectious-and-parasitic-diseases/">Center for Global Infectious and Parasitic Diseases</a></p> <p><strong>Contact</strong><br /> Sylvia Jebiwott, MPH <a href="mailto:sylvia.jebiwott@ucsf.edu">sylvia.jebiwott@ucsf.edu</a><br /> Sydney Fine, MPH <a href="mailto:sydney.fine@ucsf.edu">sydney.fine@ucsf.edu</a></p> <p><strong>More information<br /> </strong><a href="https://clinicaltrials.gov/study/NCT05690841?term=focal%20mass%20drug%20administration%20for%20vivax%20malaria&rank=1">FocaL Mass Drug Administration for Vivax Malaria Elimination (FLAME)</a>, <a href="https://clinicaltrials.gov/study/NCT05567016?term=CHILD%20(Child%20Health%20and%20Infection%20with%20Low%20Density)%20&rank=1">CHILD (Child Health and Infection With Low Density) Malaria</a></p> </div> </div> </div> <div class="accordion-item"> <p class="accordion-header" id="heading5block_f4e1374ec326e7c7bcf4b20845a30c20"> <button class="accordion-button collapsed" type="button" data-bs-toggle="collapse" data-bs-target="#collapse5block_f4e1374ec326e7c7bcf4b20845a30c20" aria-expanded="true" aria-controls="collapse5block_f4e1374ec326e7c7bcf4b20845a30c20"> <span>Drugs and diagnostics</span> </button> </p> <div id="collapse5block_f4e1374ec326e7c7bcf4b20845a30c20" class="accordion-collapse collapse" aria-labelledby="heading5block_f4e1374ec326e7c7bcf4b20845a30c20" data-bs-parent="#accordion_block-block_f4e1374ec326e7c7bcf4b20845a30c20"> <div class="accordion-body"> <p>Accurate diagnosis of malaria is critical for appropriate patient management and population-level surveillance. While standard diagnostics such as microscopy and rapid diagnostic testing (RDTs) are generally considered to have reliable accuracy, the changing epidemiology of malaria in low-transmission settings presents new challenges. Specifically, a higher proportion of infections in these settings is below the reliable detection limit of RDTs and microscopy. The Malaria Elimination Initiative uses research to assess the effectiveness of existing diagnostics in low transmission settings and the factors that influence the accuracy of these tests when used for passive and active case detection for surveillance.</p> <p><strong>Countries of activity</strong><br /> Tanzania, Peru</p> <p><strong>Partners</strong><br /> Ifakara Health Institute, Swiss Tropical and Public Health Institute, Stanford University, Universidad Peruana Cayetano Heredia, PATH</p> <p><strong>Funders</strong><br /> National Institutes of Health, National Institute of Allergy and Infectious Diseases</p> <p><strong>IGHS Center</strong><br /> <a href="https://globalhealthsciences.ucsf.edu/about-us/our-centers/center-for-global-infectious-and-parasitic-diseases/">Center for Global Infectious and Parasitic Diseases</a></p> <p><strong>Contact</strong><br /> Michelle Hsiang, MD <a href="mailto:michelle.hsiang@ucsf.edu">michelle.hsiang@ucsf.edu</a><br /> Sylvia Jebiwott, MPH <a href="mailto:sylvia.jebiwott@ucsf.edu">sylvia.jebiwott@ucsf.edu</a><br /> Sydney Fine, MPH <a href="mailto:sydney.fine@ucsf.edu">sydney.fine@ucsf.edu</a></p> </div> </div> </div> <div class="accordion-item"> <p class="accordion-header" id="heading6block_f4e1374ec326e7c7bcf4b20845a30c20"> <button class="accordion-button collapsed" type="button" data-bs-toggle="collapse" data-bs-target="#collapse6block_f4e1374ec326e7c7bcf4b20845a30c20" aria-expanded="true" aria-controls="collapse6block_f4e1374ec326e7c7bcf4b20845a30c20"> <span>Open Oximetry Project</span> </button> </p> <div id="collapse6block_f4e1374ec326e7c7bcf4b20845a30c20" class="accordion-collapse collapse" aria-labelledby="heading6block_f4e1374ec326e7c7bcf4b20845a30c20" data-bs-parent="#accordion_block-block_f4e1374ec326e7c7bcf4b20845a30c20"> <div class="accordion-body"> <p>The Open Oximetry Project improves access to safe pulse oximeters worldwide by sharing data and creating new standards and technologies for oximeter validation that better account for skin color. The project brings together a diverse community of oximetry experts, including engineers, academic researchers, clinicians, community members, manufacturers, and regulatory bodies, to partner to tackle these issues.</p> <p><strong>Country of activity</strong><br /> United States</p> <p><strong>Partners</strong><br /> The UCSF Hypoxia Lab</p> <p><strong>Funders</strong><br /> The Gordon and Betty Moore Foundation, Robert Wood Johnson Foundation, PATH with funding from Unitaid, Patrick J. McGovern Foundation, U.S. Food and Drug Administration, USAID-STAR Sustaining Technical and Analytic Resources (STAR) Project, The UCSF Hypoxia Lab</p> <p><strong>IGHS Center</strong><br /> <a href="https://globalhealthsciences.ucsf.edu/about-us/our-centers/center-for-health-equity-in-surgery-and-anesthesia/">Center for Health Equity in Surgery and Anesthesia</a></p> <p><strong>Contact</strong><br /> Michael Lipnick, MD <a href="mailto:michael.lipnick@ucsf.edu">michael.lipnick@ucsf.edu</a></p> <p><strong>More information</strong><br /> <a href="https://openoximetry.org/">Open Oximetry</a></p> </div> </div> </div> <div class="accordion-item"> <p class="accordion-header" id="heading7block_f4e1374ec326e7c7bcf4b20845a30c20"> <button class="accordion-button collapsed" type="button" data-bs-toggle="collapse" data-bs-target="#collapse7block_f4e1374ec326e7c7bcf4b20845a30c20" aria-expanded="true" aria-controls="collapse7block_f4e1374ec326e7c7bcf4b20845a30c20"> <span>Pacific Southwest Center for Emergency Public Health</span> </button> </p> <div id="collapse7block_f4e1374ec326e7c7bcf4b20845a30c20" class="accordion-collapse collapse" aria-labelledby="heading7block_f4e1374ec326e7c7bcf4b20845a30c20" data-bs-parent="#accordion_block-block_f4e1374ec326e7c7bcf4b20845a30c20"> <div class="accordion-body"> <p>The Pacific Southwest Center for Emergency Public Health collaborates with local, state and tribal health departments across California, Arizona, Nevada, Hawaii and U.S.-affiliated Pacific territories to strengthen our region’s capacity to prepare for and respond to public health threats.</p> <p><strong>Country of activity</strong><br /> United States</p> <p><strong>Partners</strong></p> <ul> <li>University of California, Los Angeles</li> <li>Public Health Institute</li> <li>University Hawaiʻi at Mānoa</li> <li>University of Nevada, Reno</li> </ul> <p><strong>Funder</strong><br /> U.S. Centers for Disease Control and Prevention</p> <p><strong>IGHS Center</strong><br /> <a href="https://globalhealthsciences.ucsf.edu/about-us/our-centers/center-for-global-strategic-information-and-public-health-practice/">Center for Global Strategic Information and Public Health Practice</a></p> <p><strong>Contact</strong><br /> Karen Horn, MBA, MPH <a href="mailto:Karen.White@ucsf.edu">Karen.White@ucsf.edu</a></p> <p><strong>More information</strong><br /> <a href="https://globalhealthsciences.ucsf.edu/about-us/our-centers/center-for-global-strategic-information-and-public-health-practice/pacific-southwest-center-for-emergency-public-health/">Pacific Southwest Center for Emergency Public Health</a></p> </div> </div> </div> <div class="accordion-item"> <p class="accordion-header" id="heading8block_f4e1374ec326e7c7bcf4b20845a30c20"> <button class="accordion-button collapsed" type="button" data-bs-toggle="collapse" data-bs-target="#collapse8block_f4e1374ec326e7c7bcf4b20845a30c20" aria-expanded="true" aria-controls="collapse8block_f4e1374ec326e7c7bcf4b20845a30c20"> <span>Vector Control</span> </button> </p> <div id="collapse8block_f4e1374ec326e7c7bcf4b20845a30c20" class="accordion-collapse collapse" aria-labelledby="heading8block_f4e1374ec326e7c7bcf4b20845a30c20" data-bs-parent="#accordion_block-block_f4e1374ec326e7c7bcf4b20845a30c20"> <div class="accordion-body"> <p>Despite significant progress in the fight against malaria, 239,000 cases were reported in the Greater Mekong Subregion in 2019, with most cases reported in Cambodia. Multidrug-resistant malaria remains a threat to regional elimination goals and global health security, and mobile and migrant populations, including forest-goers and forest rangers, remain at the highest risk for malaria. Moreover, many malaria-transmitting mosquitoes in the region bite and rest outdoors, yet the availability of effective protection against outdoor-biting mosquitoes is severely limited. One vector control project, Project BITE, is assessing the entomological protective efficacy, as well as the acceptability, durability, and cost, of a curated forest pack of bite prevention tools compared to the standard of care among high-risk forest rangers and forest-going populations in Cambodia, following evaluations of the same tools through semi-field studies in Thailand. Ultimately, Project BITE aims to inform the scale-up of effective outdoor bite prevention tools across Cambodia, the Greater Mekong Subregion, and the Asia Pacific region to support near-term malaria elimination goals.</p> <p><strong>Countries of activity</strong><br /> Thailand, Cambodia</p> <p><strong>Partners</strong><br /> University of Notre Dame, Swiss Tropical and Public Health Institute, the Armed Forces Research Institute of Medical Sciences in Thailand, Kasetsart University in Thailand, Cambodia’s National Center for Parasitology, Entomology, and Malaria Control</p> <p><strong>Funder</strong><br /> Australia’s Department of Foreign Affairs and Trade through the Innovative Vector Control Consortium</p> <p><strong>IGHS Center</strong><br /> <a href="https://globalhealthsciences.ucsf.edu/about-us/our-centers/center-for-global-infectious-and-parasitic-diseases/">Center for Global Infectious and Parasitic Diseases</a></p> <p><strong>Contact</strong><br /> Elodie Vajda <a href="mailto:elodie.vajda@ucsf.edu">elodie.vajda@ucsf.edu</a></p> <p><strong>More information</strong><br /> <a href="https://www.shrinkingthemalariamap.org/our-work/vector-control/research/project-bite">Project BITE</a></p> </div> </div> </div> </div> </div> </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="flex-basis:25%"></div> </div> </div> </div> </article> </main> </div> </div> <footer id="colophon" class="site-footer"> <div class="container"> <div class="footercol footercol--1"> <a class="footer-logo" href="https://globalhealthsciences.ucsf.edu"> <img src="https://globalhealthsciences.ucsf.edu/wp-content/plugins/phastpress/phast.php?service=images&src=https%3A%2F%2Fglobalhealthsciences.ucsf.edu%2Fwp-content%2Fuploads%2F2023%2F09%2FScreenshot-2023-08-31-at-3.39.25-PM.png&cacheMarker=1695136469-80618&token=3d26582a7786e0ff" 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}),(function(){var config=phast.config["script-proxy-service"];var urlPattern=/^(https?:)?\/\//;var typePattern=/^\s*(application|text)\/(x-)?(java|ecma|j|live)script/i;var cacheMarker=Math.floor((new Date).getTime()/1e3/config.urlRefreshTime);var whitelist=compileWhitelistPatterns(config.whitelist);phast.scripts.push(function(){overrideDOMMethod("appendChild");overrideDOMMethod("insertBefore")});function compileWhitelistPatterns(a){var b=/^(.)(.*)\1([a-z]*)$/i;var c=[];a.forEach(function(d){var e=b.exec(d);if(!e){window.console&&window.console.log("Phast: Not a pattern:",d);return}try{c.push(new RegExp(e[2],e[3]))}catch(f){window.console&&window.console.log("Phast: Failed to compile pattern:",d)}});return c}function checkWhitelist(g){for(var h=0;h<whitelist.length;h++){if(whitelist[h].exec(g)){return true}}return false}function overrideDOMMethod(i){var j=Element.prototype[i];var k=function(){var l=processNode(arguments[0]);var m=j.apply(this,arguments);l();return m};Element.prototype[i]=k;window.addEventListener("load",function(){if(Element.prototype[i]===k){delete Element.prototype[i]}})}function processNode(n){if(!n||n.nodeType!==Node.ELEMENT_NODE||n.tagName!=="SCRIPT"||!urlPattern.test(n.src)||n.type&&!typePattern.test(n.type)||n.src.substr(0,config.serviceUrl.length)===config.serviceUrl||!checkWhitelist(n.src)){return function(){}}var o=n.src;n.src=phast.buildServiceUrl(config,{service:"scripts",src:o,cacheMarker:cacheMarker});n.setAttribute("data-phast-rewritten","");return function(){n.src=o}} }),(function(){(function(){var a=function(){if(!("FontFace"in window)){return false}var b=new FontFace("t",'url( "data:font/woff2;base64,d09GMgABAAAAAADwAAoAAAAAAiQAAACoAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAABmAALAogOAE2AiQDBgsGAAQgBSAHIBuDAciO1EZ3I/mL5/+5/rfPnTt9/9Qa8H4cUUZxaRbh36LiKJoVh61XGzw6ufkpoeZBW4KphwFYIJGHB4LAY4hby++gW+6N1EN94I49v86yCpUdYgqeZrOWN34CMQg2tAmthdli0eePIwAKNIIRS4AGZFzdX9lbBUAQlm//f262/61o8PlYO/D1/X4FrWFFgdCQD9DpGJSxmFyjOAGUU4P0qigcNb82GAAA" ) format( "woff2" )',{});b.load()["catch"](function(){});return b.status=="loading"||b.status=="loaded"}();if(a){return}console.log("[Phast] Browser does not support WOFF2, falling back to original stylesheets");Array.prototype.forEach.call(document.querySelectorAll("style[data-phast-ie-fallback-url]"),function(c){var d=document.createElement("link");if(c.hasAttribute("media")){d.setAttribute("media",c.getAttribute("media"))}d.setAttribute("rel","stylesheet");d.setAttribute("href",c.getAttribute("data-phast-ie-fallback-url"));c.parentNode.insertBefore(d,c);c.parentNode.removeChild(c)});Array.prototype.forEach.call(document.querySelectorAll("style[data-phast-nested-inlined]"),function(e){e.parentNode.removeChild(e)})})(); }),(function(){phast.stylesLoading=0;var resourceLoader=phast.ResourceLoader.instance;phast.forEachSelectedElement("style[data-phast-params]",function(a){var b=a.getAttribute("data-phast-params");var c=phast.ResourceLoader.RequestParams.fromString(b);phast.stylesLoading++;resourceLoader.get(c).then(function(d){a.textContent=d;a.removeAttribute("data-phast-params")}).catch(function(e){console.warn("[Phast] Failed to load CSS",c,e);var f=a.getAttribute("data-phast-original-src");if(!f){console.error("[Phast] No data-phast-original-src on <style>!",a);return}console.info("[Phast] Falling back to <link> element for",f);var g=document.createElement("link");g.href=f;g.media=a.media;g.rel="stylesheet";g.addEventListener("load",function(){if(a.parentNode){a.parentNode.removeChild(a)}});a.parentNode.insertBefore(g,a.nextSibling)}).finally(function(){phast.stylesLoading--;if(phast.stylesLoading===0&&phast.onStylesLoaded){phast.onStylesLoaded()}})});(function(){var h=[];phast.forEachSelectedElement("style[data-phast-original-id]",function(i){var j=i.getAttribute("data-phast-original-id");if(h[j]){return}h[j]=true;console.warn("[Phast] The style element with id",j,"has been split into multiple style tags due to @import statements and the id attribute has been removed. Normally, this does not cause any issues.")})})(); }),(function(){var Promise=phast.ES6Promise;var hasCurrentScript=!!document.currentScript;phast.ScriptsLoader={};phast.ScriptsLoader.getScriptsInExecutionOrder=function(a,b){var c=Array.prototype.slice.call(a.querySelectorAll('script[type="text/phast"]')).filter(g);var d=[],e=[];for(var f=0;f<c.length;f++){if(getSrc(c[f])!==undefined&&isDefer(c[f])){e.push(c[f])}else{d.push(c[f])}}return d.concat(e).map(function(j){return b.makeScriptFromElement(j)});function g(k){try{var l=phast.config.scriptsLoader.csp}catch(m){return true}if(l.nonce==null){return true}if(k.nonce===l.nonce){return true}try{h(l,k)}catch(n){console.error("Could not send CSP report due to error:",n)}if(l.reportOnly){console.warn("Script with missing or invalid nonce would not be executed (but report-only mode is enabled):",k);return true}console.warn("Script with missing or invalid nonce will not be executed:",k);return false}function h(o,p){var q={"blocked-uri":getSrc(p),disposition:o.reportOnly?"report":"enforce","document-uri":location.href,referrer:a.referrer,"script-sample":i(p),implementation:"phast"};try{p.dispatchEvent(new SecurityPolicyViolationEvent("securitypolicyviolation",{blockedURI:q["blocked-uri"],disposition:q["disposition"],documentURI:q["document-uri"],effectiveDirective:"script-src-elem",originalPolicy:"phast",referrer:q["referrer"],sample:q["script-sample"],statusCode:200,violatedDirective:"script-src-elem"}))}catch(s){console.error("[Phast] Could not dispatch securitypolicyviolation event",s)}if(!o.reportUri){return}var r={"csp-report":q};fetch(o.reportUri,{method:"POST",headers:{"Content-Type":"application/csp-report"},credentials:"same-origin",redirect:"error",keepalive:true,body:JSON.stringify(r)})}function i(t){if(!t.hasAttribute("src")){return t.textContent.substr(0,40)}}};phast.ScriptsLoader.executeScripts=function(u){var v=u.map(function(x){return x.init()});var w=Promise.resolve();u.forEach(function(y){w=phast.ScriptsLoader.chainScript(w,y)});return w.then(function(){return Promise.all(v).catch(function(){})})};phast.ScriptsLoader.chainScript=function(z,A){var B;try{if(A.describe){B=A.describe()}else{B="unknown script"}}catch(C){B="script.describe() failed"}return z.then(function(){var D=A.execute();D.then(function(){console.debug("✓",B)});return D}).catch(function(E){console.error("✘",B);if(E){console.log(E)}})};var insertBefore=window.Element.prototype.insertBefore;phast.ScriptsLoader.Utilities=function(F){this._document=F;var G=0;function H(R){return new Promise(function(S){var T="PhastCompleteScript"+ ++G;var U=I(R);var V=I(T+"()");window[T]=W;F.body.appendChild(U);F.body.appendChild(V);function W(){S();F.body.removeChild(U);F.body.removeChild(V);delete window[T]}})}function I(X){var Y=F.createElement("script");Y.textContent=X;Y.nonce=phast.config.scriptsLoader.csp.nonce;return Y}function J(Z){var 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sa=Promise.resolve();var ta;if(isAsync(pa)){ta="async"}else if(isDefer(pa)){ta="defer"}F.write=function(xa){if(ta){console.warn("document.write call from "+ta+" script ignored");return}ua(xa)};F.writeln=function(ya){if(ta){console.warn("document.writeln call from "+ta+" script ignored");return}ua(ya+"\n")};function ua(za){var Aa=F.createElement("div");Aa.innerHTML=za;var Ba=va(Aa);if(ra&&ra.parentNode!==pa.parentNode){ra=pa.nextElementSibling}while(Aa.firstChild){pa.parentNode.insertBefore(Aa.firstChild,ra)}Ba.map(wa)}function va(Ca){return Array.prototype.slice.call(Ca.getElementsByTagName("script")).filter(function(Da){var Ea=Da.getAttribute("type");return!Ea||/^(text|application)\/javascript(;|$)/i.test(Ea)})}function wa(Fa){var Ga=new phast.ScriptsLoader.Scripts.Factory(F);var Ha=Ga.makeScriptFromElement(Fa);sa=phast.ScriptsLoader.chainScript(sa,Ha)}return qa().then(function(){return sa}).finally(function(){delete F.write;delete F.writeln})}function 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script"}};phast.ScriptsLoader.Scripts.AsyncBrowserScript=function(Qa,Ra){var Sa;this._utils=Qa;this._element=Ra;this.init=function(){Qa.addPreload(getSrc(Ra));return new Promise(function(Ta){Sa=Ta})};this.execute=function(){var Ua=Qa.copyElement(Ra);Qa.restoreOriginals(Ua);Qa.replaceElement(Ra,Ua).then(Sa).catch(Sa);return Promise.resolve()};this.describe=function(){return"async script at "+getSrc(Ra)}};phast.ScriptsLoader.Scripts.SyncBrowserScript=function(Va,Wa){this._utils=Va;this._element=Wa;this.init=function(){Va.addPreload(getSrc(Wa));return Promise.resolve()};this.execute=function(){var Xa=Va.copyElement(Wa);Va.restoreOriginals(Xa);return Va.writeProtectAndReplaceElement(Wa,Xa)};this.describe=function(){return"sync script at "+getSrc(Wa)}};phast.ScriptsLoader.Scripts.AsyncAJAXScript=function(Ya,Za,$a,_a){this._utils=Ya;this._element=Za;this._fetch=$a;this._fallback=_a;var a0;var b0;this.init=function(){a0=$a(Za);return new 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r0;if(q0.getAttribute("data-phast-debug-force-method")&&window.location.host.match(/\.test$/)){return new m0[q0.getAttribute("data-phast-debug-force-method")](n0,q0)}if(o0(q0)){if(isAsync(q0)){r0=new m0.AsyncBrowserScript(n0,q0);return l0?new m0.AsyncAJAXScript(n0,q0,l0,r0):r0}r0=new m0.SyncBrowserScript(n0,q0);return l0?new m0.SyncAJAXScript(n0,q0,l0,r0):r0}if(p0(q0)){return new m0.InlineScript(n0,q0)}if(isAsync(q0)){return new m0.AsyncBrowserScript(n0,q0)}return new m0.SyncBrowserScript(n0,q0)};function o0(s0){return s0.hasAttribute("data-phast-params")}function p0(t0){return!t0.hasAttribute("src")}};function getSrc(u0){if(u0.hasAttribute("data-phast-original-src")){return u0.getAttribute("data-phast-original-src")}else if(u0.hasAttribute("src")){return u0.getAttribute("src")}}function isAsync(v0){return v0.hasAttribute("async")||v0.hasAttribute("data-phast-async")}function isDefer(w0){return w0.hasAttribute("defer")||w0.hasAttribute("data-phast-defer")} }),(function(){var 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setReadyState(g){try{Object.defineProperty(document,"readyState",{configurable:true,get:function(){return g}})}catch(h){console.warn("[Phast] Unable to override document.readyState on this browser: ",h)}}function restoreReadyState(){i().then(function(){setReadyState("interactive");triggerEvent(document,"readystatechange");return i()}).then(function(){triggerEvent(document,"DOMContentLoaded");return i()}).then(function(){delete document["readyState"];triggerEvent(document,"readystatechange");if(loadFiltered){triggerEvent(window,"load")}loadFiltered=true});function i(){return new Promise(function(j){(function k(l){if(didSetTimeout&&l<10){didSetTimeout=false;originalSetTimeout.call(window,function(){k(l+1)})}else{requestAnimationFrame(j)}})(0)})}}function triggerEvent(m,n){var o=document.createEvent("Event");o.initEvent(n,true,true);m.dispatchEvent(o)}function fetchScript(p){return 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