Patients with IBD at greater risk for post-endoscopy complications

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<script type="text/javascript"> jQuery(".nav>li:last>a").addClass("last"); //fix for IE last-child style </script>   <div id="main-content">  <p id="breadcrumbs"> <a href="/web/20131007082915/http://www.healio.com/"> Healio</a> <span>›</span> <a href="/web/20131007082915/http://www.healio.com/gastroenterology"> Gastroenterology</a> <span>›</span> <a href="/web/20131007082915/http://www.healio.com/gastroenterology/inflammatory-bowel-disease"> Inflammatory Bowel Disease</a> <span>›</span> <a href="/web/20131007082915/http://www.healio.com/gastroenterology/inflammatory-bowel-disease/news"> News</a> </p>   <div id="SeeAlso" class="related-links"><h3>See Also</h3><ul><li><a href="https://web.archive.org/web/20131007082915/http://www.healio.com/gastroenterology/inflammatory-bowel-disease/news/online/%7B90a24150-fad2-4704-9dc4-65b085c6be8a%7D/osteoporosis-risk-heightened-among-patients-with-crohns-disease">Osteoporosis risk heightened among patients with Crohn's ...</a></li><li><a href="https://web.archive.org/web/20131007082915/http://www.healio.com/gastroenterology/inflammatory-bowel-disease/news/online/%7B909d707c-97d9-41d8-8a30-d70d14e135b8%7D/elderly-patients-with-ibd-prone-to-depression">Elderly patients with IBD prone to depression ...</a></li><li><a href="https://web.archive.org/web/20131007082915/http://www.healio.com/gastroenterology/inflammatory-bowel-disease/news/online/%7B7ba7c404-906f-49fa-a381-f8da13b17a97%7D/no-link-between-parental-ibd-asthma-risk-in-offspring">No link between parental IBD, asthma risk in offspring ...</a></li></ul></div> <input name="layout_0$maincontent_0$seeAlsoInsertUnderParagraph" type="hidden" id="layout_0_maincontent_0_seeAlsoInsertUnderParagraph" value="1"/>  <div class="content"> <h2> Patients with IBD at greater risk for post-endoscopy complications</h2> <h3 class="deck"> <a target="_blank" href="https://web.archive.org/web/20131007082915/http://www.cghjournal.org/article/S1542-3565%2813%2900622-8/abstract">Ferreira J. <em>Clin Gastroent</em><em>e</em><em>rol Hepatol</em>. 2013;11:1288-1293.</a></h3> <p class="main-subtitle"> </p> <div class="social-links-top"> <ul class="share"> <li class="l1"><a href="javascript:void(0)" class="facebook-link" target="_new">Facebook</a></li> <li class="l2"><a href="javascript:void(0)" class="twitter-link" target="_new">Tweet</a></li> <li class="l3"><a href="javascript:void(0)" class="linkedin-link">Share</a></li> </ul> </div> <ul class="meta-info"> <li> October 3, 2013</li> </ul> <div class="wyContent"> <p>Complications and the need for medical care following an endoscopic procedure were more common among patients with IBD than controls in a recent study.</p> <p>Researchers evaluated health care use within 14 days of outpatient colonoscopy, esophagogastroduodenoscopy or sigmoidoscopy among patients with <a href="https://web.archive.org/web/20131007082915/http://www.healio.com/gastroenterology/inflammatory-bowel-disease" target="_blank">IBD</a> and controls treated at Beth Israel Deaconess Medical Center in Boston between March 1 and Nov. 30, 2007. The cohort included 685 procedures performed in 622 patients with IBD, and 17,330 procedures performed on controls. Complications, defined as endoscopy-related ED visits within 14 days of the procedure, were observed in both groups. Investigators also performed retrospective chart reviews of patients with IBD to assess health care use after procedures.</p> <p>Complications were observed in 1.17% of patients and 0.96% of controls (<em>P</em><em>=</em>.55). Within 2 weeks of endoscopy, 73 patients required health care use, 26 cases considered procedure related, for a post-procedure health care use rate of 3.8%. Fifty-four percent of these incidents were minor; the remainder required ED or hospital admission. Post-procedural complications requiring inpatient admission occurred in seven cases.</p> <p>Using a Markov Monte Carlo model simulating routine screening and surveillance colonoscopy in 10,000 patients with IBD and 10,000 patients in the general population, the investigators calculated a 12.7% lifetime risk for complications, compared with 2% in the general population (<em>P</em><.001), for a relative risk of 6.3 (95% CI, 5.4-7.3) among those with IBD. Likewise, patients had a higher mean number of complications per person (0.13 vs. 0.02; <em>P</em><.001) and underwent more colonoscopies (13 vs. 3; <em>P</em><.001).</p> <p>“This study suggests that IBD and non-IBD cohorts have similar rates of endoscopy-related complications,” researcher <strong>Jason Ferreira, MD,</strong> division of gastroenterology at the medical center, told <em>Healio.com</em>. “However, our data propose that IBD patients will experience a six-fold significantly higher projected lifetime risk of post-endoscopic complications, given the increased volume of procedures this group endures.</p> <p>“This amount of health care interaction following endoscopy represents a sizable burden to both the patient and physician, which was previously underappreciated.”</p> <p><strong>Disclosure: </strong>The researchers report no relevant financial disclosures.</p> </div>  <div class="fig left"> <p class="figcaption"> </p> </div> <div class="wyPagination">   </div>  <div class="follow"> <img src="/web/20131007082915im_/http://www.healio.com/~/media/Images/News/FollowUs.jpg" id="layout_0_maincontent_1_SocialFollow_socialfollow" name="socialfollow" alt="Follow us" usemap="#followus" border="0"/> <map id="followus" name="followus"> <area id="layout_0_maincontent_1_SocialFollow_followfb" shape="rect" coords="51,5,5,51" target="_blank" href="https://web.archive.org/web/20131007082915/https://www.facebook.com/HealioGastroenterology?ref=hl" alt="Follow us on Facebook"></area> <area id="layout_0_maincontent_1_SocialFollow_followtw" shape="rect" coords="270,3,320,50" target="_blank" href="https://web.archive.org/web/20131007082915/https://twitter.com/healiogastro" alt="Follow us on Twitter"></area> </map> </div> </div>  <div class="social-links"> <div class="fb-like" data-send="false" data-width="300" data-show-faces="true" data-action="recommend"></div> <ul class="share"> <li><a href="javascript:void(0)" id="twitter" class="twitter-link" target="_new">Tweet</a></li> <li><a href="javascript:void(0)" id="facebook" class="facebook-link" target="_new">Share</a></li> <li class="linkedin"><a href="javascript:void(0)" id="linkedin" class="linkedin-link">Link</a></li> <li><span class="db-wrapper"><span class="g-plusone" data-size="tall" data-annotation="none"></span></span></li> <li><a href="javascript:void(0)" id="email">Email</a></li> <li class="last"><a href="javascript:void(0)" id="print">Print</a></li> </ul> <input name="layout_0$maincontent_1$SocialMedia$articleItemForTweet" type="hidden" id="layout_0_maincontent_1_SocialMedia_articleItemForTweet" value="{0F155382-7326-4527-81DF-77027D9DDA66}"/> <input name="layout_0$maincontent_1$SocialMedia$tweettext" type="hidden" id="layout_0_maincontent_1_SocialMedia_tweettext" class="tweettext" value="Patients with IBD at greater risk for post-endoscopy complications "/> <input name="layout_0$maincontent_1$SocialMedia$tweeturl" type="hidden" id="layout_0_maincontent_1_SocialMedia_tweeturl" class="tweeturl"/> </div>  <div id="respond"> <h4> Comments</h4> <script language="javascript" type="text/javascript"> var idcomments_acct = 'aa6ff53f9870e40f92f83e1b5df3cddf'; var idcomments_post_id = '{0F155382-7326-4527-81DF-77027D9DDA66}'; var idcomments_post_url; </script> <span id="IDCommentsPostTitle" style="display: none"></span> <script type="text/javascript" src="https://web.archive.org/web/20131007082915js_/http://www.intensedebate.com/js/genericCommentWrapperV2.js"></script> <p class="comment-notes"> Healio is intended for health care provider use and all comments will be posted at the discretion of the editors. 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