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url(https://somalogic.com/wp-content/uploads/2023/10/11KHero-scaled.jpg);height: 684px;" title="Inner cave background with 11K in large text"> <div class="container"> <div class="grid"> <div class="cell-md-9"> <p class="breadcrumbs"><a href="/">Home</a> / Platform / Our Science / <span class="blue">SomaScan 11K Assay</span></p> <h1>Broader and deeper protein content for optimized discovery potential</h1> <p>Accelerate your research in oncology, neurology, cardiology, infectious disease, and more.</p> <p><a class="btn purple mt-60 mb-60" href="https://share.hsforms.com/1jQWm31fWRtGdwkhvRPNDJA3zbc6" target="_blank" rel="noopener">Download our Tech Note to learn how the SomaScan 11K Assay works</a></p> </div> </div> </div> </div><div class="wrap white align-center" id="wrap_0" title=""> <div class="container"> <div class="grid"><div class="text-block cell-md-12 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="a-center mb-60"><h2>The SomaScan® 11K Assay:<br /> Your access to half of the human proteome</h2> <p>The SomaScan Assay is the only proteomic technology capable of measuring rapidly (high throughput), broadly (thousands of proteins simultaneously), and deeply (high-and low-abundance proteins).</p> <p>This industry-leading multiplex platform provides 11,000 total protein measurements, including 10,000 unique human proteins measured. That’s half the human proteome.</p> <h3>What does this mean for your research?</h3> <p>The study of proteomics is essential for the discovery of novel bimarkers and potentially causative mechanisms. Acquiring such robust data on numerous proteins at once offers groundbreaking insights into predicting response, mechanisms of action and biomarker translation – and with the confidence that you are seeing it all.</p> </div> </div><div class="text-block cell-md-6 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="pr-40"><h2>The broadest, deepest disease coverage</h2> <p>The SomaScan 11,000-plex menu is the most powerful proteomics solution today, enabling researchers to decipher human biology by casting the widest net possible.</p> <p>Benefit from a high-plex, sensitive, and reproducible proteomic tool designed for drug discovery, pre-clinical, and clinical drug development across a wide range of diseases and conditions.</p> <p>Do you need to compare data from SomaScan 7K or 5K projects with the new SomaScan 11K platform? Or are you interested in learning more about what the 11k assay can do for your research? Maximize your data’s potential with our comprehensive tools that allow you to seamlessly compare data across assay versions and eliminate the need to run additional samples for data bridging.</p> <p><strong>The comprehensive coverage of a broad selection of protein targets is mapped to biological processes and various disease areas, shown at right.</strong></p> </div> </div><div class="text-block cell-md-6 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="a-center"><div style="position:relative;width:auto;padding:0 0 140.00%;height:0;top:0;left:0;bottom:0;right:0;margin:0;border:0 none" id="experience-653f2462b5140" data-aspectRatio="0.7143"><iframe title="11K Percent Growth Chart" allowfullscreen src="https://view.ceros.com/somalogic/11k-percent-growth-chart" style="position:absolute;top:0;left:0;bottom:0;right:0;margin:0;padding:0;border:0 none;height:1px;width:1px;min-height:100%;min-width:100%" frameborder="0" class="ceros-experience" scrolling="no"></iframe></div><script type="text/javascript" src="https://view.ceros.com/scroll-proxy.min.js" data-ceros-origin-domains="view.ceros.com"></script></div> </div></div> </div> </div><div class="wrap black align-center" id="SignUpOne" style="background-image: url(https://somalogic.com/wp-content/uploads/2023/10/SL_Black_Pink_Gradient_BG_v2.jpg)" title="Pink and black mesh gradient background"> <div class="container"> <div class="grid"><div class="text-block cell-md-6 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="a-center"><p><img loading="lazy" decoding="async" class="aligncenter wp-image-6089" src="https://somalogic.com/wp-content/uploads/2023/10/11KLayered_web_v3.png" alt="11K graphic, representing 11,000 measurable human proteins using the SomaScan Assay" width="601" height="339" srcset="https://somalogic.com/wp-content/uploads/2023/10/11KLayered_web_v3.png 900w, https://somalogic.com/wp-content/uploads/2023/10/11KLayered_web_v3-300x169.png 300w, https://somalogic.com/wp-content/uploads/2023/10/11KLayered_web_v3-768x433.png 768w" sizes="auto, (max-width: 601px) 100vw, 601px" /></p> </div> </div><div class="text-block cell-md-6 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="pl-40"><h2>Get started now</h2> <div style="width: 375px"><a class="btn purple" style="width: 100%" href="https://share.hsforms.com/1jQWm31fWRtGdwkhvRPNDJA3zbc6" target="_blank" rel="noopener">Learn more about 11K from our tech note</a><br /> <a class="btn white-border" style="width: 100%;margin-top: 24px" href="https://share.hsforms.com/1tuK-RnQUQHy0R2pKjyptxw3zbc6" target="_blank" rel="noopener">Or contact us to learn more about 11K</a></div> </div> </div></div> </div> </div><div class="wrap white " id="wrap_2" title=""> <div class="container"> <div class="grid"><div class="text-block cell-md-12 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="a-center"><h2>Detect proteins across every major biological pathway</h2> <h3 style="margin-bottom: 30px">% Proteomic Coverage by Platform for Selected Pathways</h3> </div> </div><div class="text-block cell-md-10 cell-offset-md-1 cell-sm-12 cell-offset-sm-0" > <div class="a-center desktop"><div style="position:relative;width:auto;padding:0 0 55.15%;height:0;top:0;left:0;bottom:0;right:0;margin:0;border:0 none" id="experience-66b163262cc37" data-aspectRatio="1.8133"><iframe title="Pathways - Horizontal" allowfullscreen src="https://view.ceros.com/somalogic/pathways-vertical-only-1" style="position:absolute;top:0;left:0;bottom:0;right:0;margin:0;padding:0;border:0 none;height:1px;width:1px;min-height:100%;min-width:100%" frameborder="0" class="ceros-experience" scrolling="no"></iframe></div><script type="text/javascript" src="https://view.ceros.com/scroll-proxy.min.js" data-ceros-origin-domains="view.ceros.com"></script></div> </div><div class="text-block cell-md-12 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="a-center mobile"><div style="position:relative;width:auto;padding:0 0 81.49%;height:0;top:0;left:0;bottom:0;right:0;margin:0;border:0 none" id="experience-66d8baa99138d" data-aspectRatio="1.2272"><iframe title="Pathways - Horizontal Mobile" allowfullscreen src="https://view.ceros.com/somalogic/pathways-vertical-only-1-1?heightOverride=625" style="position:absolute;top:0;left:0;bottom:0;right:0;margin:0;padding:0;border:0 none;height:1px;width:1px;min-height:100%;min-width:100%" frameborder="0" class="ceros-experience" scrolling="no"></iframe></div><script type="text/javascript" src="https://view.ceros.com/scroll-proxy.min.js" data-ceros-origin-domains="view.ceros.com"></script></div> </div><div class="text-block cell-md-12 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="a-center"><p><a class="btn black-border" style="margin-top: 30px" href="https://menu.somalogic.com" target="_blank" rel="noopener">View the entire menu</a></p> </div> </div></div> </div> </div><div class="wrap grey " id="wrap_3" title=""> <div class="container"> <div class="grid"><div class="text-block cell-md-12 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="mb-60"><div style="position:relative;width:auto;padding:0 0 25.74%;height:0;top:0;left:0;bottom:0;right:0;margin:0;border:0 none" id="experience-66b23e6879dd2" data-aspectRatio="3.8857"><iframe title="11K WyssCoray Quote - Horizontal" allowfullscreen src="https://view.ceros.com/somalogic/11k-landing-page-quote-1-3" style="position:absolute;top:0;left:0;bottom:0;right:0;margin:0;padding:0;border:0 none;height:1px;width:1px;min-height:100%;min-width:100%" frameborder="0" class="ceros-experience" scrolling="no"></iframe></div><script type="text/javascript" src="https://view.ceros.com/scroll-proxy.min.js" data-ceros-origin-domains="view.ceros.com"></script></div> </div><div class="text-block cell-md-12 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="a-center"><div style="position:relative;width:auto;padding:0 0 34.47%;height:0;top:0;left:0;bottom:0;right:0;margin:0;border:0 none" id="experience-66b241736731d" data-aspectRatio="2.9013"><iframe title="11K Libermann Quote - Horizontal" allowfullscreen src="https://view.ceros.com/somalogic/11k-landing-page-quote-1-1-1" style="position:absolute;top:0;left:0;bottom:0;right:0;margin:0;padding:0;border:0 none;height:1px;width:1px;min-height:100%;min-width:100%" frameborder="0" class="ceros-experience" scrolling="no"></iframe></div><script type="text/javascript" src="https://view.ceros.com/scroll-proxy.min.js" data-ceros-origin-domains="view.ceros.com"></script></div> </div></div> </div> </div><div class="wrap white " id="orthogonalValidation" title=""> <div class="container"> <div class="grid"><div class="text-block cell-md-6 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="pr-40"><h2>Our precision is backed by orthogonal validation</h2> <p>From our original 1,300-plex menu to today, we have maintained consistent quality metrics for specificity, sensitivity, reproducibility, and more.</p> <p>Our customers rely on consistent quality, so they know their data is always accurate and meaningful. To meet their needs, we provide the largest number of protein measurements and the greatest number of orthogonally confirmed protein reagents in the proteomics industry.</p> <h3>Primary validation of all SOMAmer® Reagents includes:</h3> <ul> <li>Determination of equilibrium binding affinity dissociation constant</li> <li>Pull down assay of cognate protein from buffer</li> <li>Demonstration of buffer dose response in the SomaScan Assay</li> <li>Estimation of endogenous cognate protein signals in plasma</li> <li>Required for inclusion in the SomaScan Assay</li> </ul> </div> </div><div class="text-block cell-md-6 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="pl-40"><div style="background-color: #faf8fd;padding: 40px"> <p><strong><img loading="lazy" decoding="async" class="alignnone size-large wp-image-8773" src="https://somalogic.com/wp-content/uploads/2024/09/11K-Donut-art_8-21-2024-1024x781.png" alt="SomaScan 11K Assay Orthogonal Validation Chart" width="1024" height="781" srcset="https://somalogic.com/wp-content/uploads/2024/09/11K-Donut-art_8-21-2024-1024x781.png 1024w, https://somalogic.com/wp-content/uploads/2024/09/11K-Donut-art_8-21-2024-300x229.png 300w, https://somalogic.com/wp-content/uploads/2024/09/11K-Donut-art_8-21-2024-768x585.png 768w, https://somalogic.com/wp-content/uploads/2024/09/11K-Donut-art_8-21-2024-1536x1171.png 1536w, https://somalogic.com/wp-content/uploads/2024/09/11K-Donut-art_8-21-2024-2048x1561.png 2048w" sizes="auto, (max-width: 1024px) 100vw, 1024px" /></strong></p> <p style="margin-top: 30px"><strong>Over 8,000</strong> SOMAmer Reagents have at least one additional form of orthogonal validation</p> <p><strong>Over 3,000</strong> SOMAmer Reagents have undergone two or more forms of orthogonal validation</p> </div> </div> </div></div> </div> </div><div class="wrap black align-center" id="11k-cta" style="background-image: url(https://somalogic.com/wp-content/uploads/2023/10/SL_Black_Pink_Gradient_BG_v2.jpg)" title="Pink and black mesh gradient background"> <div class="container"> <div class="grid"><div class="text-block cell-md-6 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="align-center"><p><img loading="lazy" decoding="async" class="alignnone wp-image-6089 size-full" src="https://somalogic.com/wp-content/uploads/2023/10/11KLayered_web_v3.png" alt="11K graphic, representing 11,000 measurable human proteins using the SomaScan Assay" width="900" height="508" srcset="https://somalogic.com/wp-content/uploads/2023/10/11KLayered_web_v3.png 900w, https://somalogic.com/wp-content/uploads/2023/10/11KLayered_web_v3-300x169.png 300w, https://somalogic.com/wp-content/uploads/2023/10/11KLayered_web_v3-768x433.png 768w" sizes="auto, (max-width: 900px) 100vw, 900px" /></p> </div> </div><div class="text-block cell-md-6 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="pl-40"><h2>Let us help you maximize your data’s potential with our comprehensive suite of tools.</h2> <div style="width: 375px"><a class="btn purple" style="width: 100%" href="https://share.hsforms.com/1jQWm31fWRtGdwkhvRPNDJA3zbc6" target="_blank" rel="noopener">Learn more about 11K from our tech note</a><br /> <a class="btn white-border" style="width: 100%;margin-top: 24px" href="https://share.hsforms.com/1tuK-RnQUQHy0R2pKjyptxw3zbc6" target="_blank" rel="noopener">Or contact us to learn more about 11K</a></div> </div> </div></div> </div> </div><div class="wrap white align-center" id="wrap_6" title=""> <div class="container"> <div class="grid"><div class="text-block cell-md-12 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="a-center"><h2>11K Platform Bridging</h2> <p>With some assay platforms, integrating data across versions can be difficult and time consuming. When you use the SomaScan platform, we make it easy for you to compare your 11K data to your 7K and 5K data.</p> </div> </div><div class="text-block cell-md-12 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="grid-parent mt-60"><div class="subgrid-item"> <div><img decoding="async" style="width: 100%;border: 2px solid #59cfdb;padding: 10px;border-radius: 4px" src="https://somalogic.com/wp-content/uploads/2024/03/platformBridge.svg" /></div> <div> <h3>Have confidence in data integration across SomaScan platforms</h3> <p>We’ve developed and qualified the method that allows you to quickly compare data from projects run across our SomaScan 5K, SomaScan 7K, and new SomaScan 11K platforms.</p> </div> </div> <div class="subgrid-item" style="margin-top: 30px"> <div><img loading="lazy" decoding="async" class="alignnone size-full wp-image-7728" style="width: 100%" src="https://somalogic.com/wp-content/uploads/2024/03/time.svg" alt="Clock icon" width="80" height="80" /></div> <div> <h3>Save time and money</h3> <p>With the SomaScan platform, we have developed simple solutions to compare 11K data to your 7K or 5K data for Human EDTA Plasma and Serum. This means your project may not require additional samples if you ever need to compare your project to a previous platform project.</p> </div> </div> <div class="subgrid-item" style="margin-top: 30px"> <div><img loading="lazy" decoding="async" class="alignnone size-full wp-image-7726" style="width: 100%" src="https://somalogic.com/wp-content/uploads/2024/03/maximizeInsight.svg" alt="Maximize insight icon" width="73" height="80" /></div> <div> <h3>Maximize your insights across long term studies</h3> <p>Our accessible, open-source tools break down data silos and unlock deeper insights across long term studies that span different versions of the SomaScan platform.</p> </div> </div> </div> </div><div class="text-block cell-md-12 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="a-center"><hr /> </div> </div><div class="text-block cell-md-6 cell-offset-md-1 cell-sm-12 cell-offset-sm-0" > <div class="a-center pr-40"><div style="position:relative;width:auto;padding:0 0 60.22%;height:0;top:0;left:0;bottom:0;right:0;margin:0;border:0 none" id="experience-66e1bf356a31c" data-aspectRatio="1.6607"><iframe title="11K Chart and Types_v2" allowfullscreen src="https://view.ceros.com/somalogic/11k-vs-7k-columns-11k-2-2-1-1" style="position:absolute;top:0;left:0;bottom:0;right:0;margin:0;padding:0;border:0 none;height:1px;width:1px;min-height:100%;min-width:100%" frameborder="0" class="ceros-experience" scrolling="no"></iframe></div><script type="text/javascript" src="https://view.ceros.com/scroll-proxy.min.js" data-ceros-origin-domains="view.ceros.com"></script></div> </div><div class="text-block cell-md-4 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="a-center"><p><img loading="lazy" decoding="async" class="aligncenter wp-image-7712 size-medium" src="https://somalogic.com/wp-content/uploads/2024/03/labMiceOnly-300x259.png" alt="Lab mice" width="300" height="259" srcset="https://somalogic.com/wp-content/uploads/2024/03/labMiceOnly-300x259.png 300w, https://somalogic.com/wp-content/uploads/2024/03/labMiceOnly-768x662.png 768w, https://somalogic.com/wp-content/uploads/2024/03/labMiceOnly-290x250.png 290w, https://somalogic.com/wp-content/uploads/2024/03/labMiceOnly.png 800w" sizes="auto, (max-width: 300px) 100vw, 300px" /><br /> <a class="btn black-border" href="/versatility/">Explore species and sample types</a></p> </div> </div><div class="text-block cell-md-12 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="a-center"><hr /> </div> </div><div class="text-block cell-md-6 cell-offset-md-1 cell-sm-12 cell-offset-sm-0" > <div class="grid-parent pr-40"><h3>SomaScan Assay services can be found at:</h3> <div class="subgrid-item subgrid-6col"> <div><img loading="lazy" decoding="async" class="alignnone wp-image-5979" src="https://somalogic.com/wp-content/uploads/2023/10/HQ_Icon_Hex_Teal.png" alt="Hexagon icon showing map marker" width="80" height="89" /></div> <div><strong>SomaLogic’s CLIA-certified, CAP-accredited laboratory (USA)</strong></div> </div> <div class="subgrid-item subgrid-6col" style="margin-top: 30px"> <div><img loading="lazy" decoding="async" class="alignnone wp-image-5980" src="https://somalogic.com/wp-content/uploads/2023/10/Global_Icon_Hex_Teal.png" alt="Hexagon icon showing globe icon" width="80" height="89" /></div> <div><strong>SomaLogic Authorized Sites (Worldwide)</strong></div> </div> </div> </div><div class="text-block cell-md-4 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="a-center"><p><img loading="lazy" decoding="async" class="aligncenter wp-image-8345 size-full" src="https://somalogic.com/wp-content/uploads/2024/07/clickableMap-7-2024.png" alt="Map of SomaLogic Authorized Sites WorldWide" width="991" height="619" srcset="https://somalogic.com/wp-content/uploads/2024/07/clickableMap-7-2024.png 991w, https://somalogic.com/wp-content/uploads/2024/07/clickableMap-7-2024-300x187.png 300w, https://somalogic.com/wp-content/uploads/2024/07/clickableMap-7-2024-768x480.png 768w" sizes="auto, (max-width: 991px) 100vw, 991px" /><br /> <a class="btn black-border" href="/authorized-sites-worldwide/">View authorized sites</a></p> </div> </div></div> </div> </div><div class="wrap black align-center" id="SignUpThree" style="background-image: url(https://somalogic.com/wp-content/uploads/2023/10/SL_Black_Pink_Gradient_BG_v2.jpg)" title="Pink and black mesh gradient background"> <div class="container"> <div class="grid"><div class="text-block cell-md-6 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="a-center"><p><img loading="lazy" decoding="async" class="alignnone wp-image-6089 size-full" src="https://somalogic.com/wp-content/uploads/2023/10/11KLayered_web_v3.png" alt="11K graphic, representing 11,000 measurable human proteins using the SomaScan Assay" width="900" height="508" srcset="https://somalogic.com/wp-content/uploads/2023/10/11KLayered_web_v3.png 900w, 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