CINXE.COM

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class="burr-flipped-content-inner burr-flipped-content-region-inner panel-panel-inner"> <div class="panel-pane pane-entity-field pane-node-field-subtitle" > <div class="pane-content"> <div class="field field-name-field-subtitle field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">The Kidney Project is awarded $1 million from KidneyX for recent advances</div></div></div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-views-panes pane-news-page-panel-pane-2" > <div class="pane-content"> <div class="view view-news-page view-id-news_page view-display-id-panel_pane_2 view-dom-id-6fe316d86e10a125d7455adb21eb4b47"> <div class="view-content"> <div class="submitted"> <div> <div class="views-field-created views-field">By Levi Gadye / Mon Jun 12, 2023</div> </div> </div> </div> </div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-node-content" > <div class="pane-content"> <div id="node-19966" class="node node-openacademy-news clearfix" about="/news/2023/06/scaling-bioartificial-kidney-ucsf" typeof="sioc:Item foaf:Document"> <span property="dc:title" content="" class="rdf-meta element-hidden"></span> <div class="content"> <div class="field field-name-field-featured-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><div id="file-168801" class="file file-image file-image-jpeg file-entity-third file-entity-element-container"> <div class="content"> <picture >  <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_third/public/featured/shuvo_roy.jpg?itok=6y1SdPO5&timestamp=1686599636 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_three_quarters/public/featured/shuvo_roy.jpg?itok=cI2wwsAT&timestamp=1686599636 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_full/public/featured/shuvo_roy.jpg?itok=cr9MveYJ&timestamp=1686599636 3x" media="(min-width: 1025px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_half/public/featured/shuvo_roy.jpg?itok=VNAITV17&timestamp=1686599636 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_three_quarters/public/featured/shuvo_roy.jpg?itok=cI2wwsAT&timestamp=1686599636 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_1_5x/public/featured/shuvo_roy.jpg?itok=lyVf7VsB&timestamp=1686599636 3x" media="(min-width: 656px) and (max-width: 1024px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_quarter/public/featured/shuvo_roy.jpg?itok=qoVmlOZM&timestamp=1686599636 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_half/public/featured/shuvo_roy.jpg?itok=VNAITV17&timestamp=1686599636 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_three_quarters/public/featured/shuvo_roy.jpg?itok=cI2wwsAT&timestamp=1686599636 3x" media="(min-width: 481px) and (max-width: 655px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_half/public/featured/shuvo_roy.jpg?itok=VNAITV17&timestamp=1686599636 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_three_quarters/public/featured/shuvo_roy.jpg?itok=cI2wwsAT&timestamp=1686599636 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_1_5x/public/featured/shuvo_roy.jpg?itok=lyVf7VsB&timestamp=1686599636 3x" media="(min-width: 431px) and (max-width: 480px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_third/public/featured/shuvo_roy.jpg?itok=6y1SdPO5&timestamp=1686599636 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_three_quarters/public/featured/shuvo_roy.jpg?itok=cI2wwsAT&timestamp=1686599636 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_full/public/featured/shuvo_roy.jpg?itok=cr9MveYJ&timestamp=1686599636 3x" media="(min-width: 0px) and (max-width: 430px)" />  <img src="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_third/public/featured/shuvo_roy.jpg?itok=6y1SdPO5&timestamp=1686599636" alt="Shuvo Roy Headshot" title="" /> </picture> <div class="field field-name-field-image-credit-term field-type-taxonomy-term-reference field-label-hidden"> <div class="field-items"> <div class="field-item even"><a href="https://elisabeth-fall.squarespace.com/" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Elisabeth Fall</a></div> </div> </div> <div class="field field-name-field-image-caption field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Shuvo Roy, PhD</p></div></div></div> </div> </div> </div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p>On June 12, The Kidney Project was awarded a $1 million Artificial Kidney Prize from KidneyX for advancing its prototype bioartificial kidney toward a full-sized, human scale, with manufacturing and ultimately clinical trials on the horizon.</p> <p><a href="https://pharm.ucsf.edu/kidney">The Kidney Project</a> is a nationwide collaboration led by Shuvo Roy, PhD of UC San Francisco and William Fissell, MD of Vanderbilt University Medical Center (VUMC), that aims to free kidney disease patients from dialysis machines and transplant waiting lists.</p> <p><a href="https://www.kidneyx.org/">KidneyX</a> is a public–private partnership between the <a href="https://www.hhs.gov/">U.S. Department of Health and Human Services</a> (HHS) and the <a href="https://www.asn-online.org/">American Society of Nephrology</a> (ASN) founded to “accelerate innovation in the prevention, diagnosis, and treatment of kidney diseases.”</p> <p>The KidneyX Prize recognizes the advances The Kidney Project has made in showing the feasibility of the bioreactor component of the bioartificial kidney to house kidney cells. “We previously showed the functional proof-of-concept of our device in an animal model,” said Roy, who is a professor of bioengineering at UCSF. “Now we can begin to create full-sized immunoprotective bioreactors that have the clinical capacity to treat patients.”</p> <p>When the kidneys fail during end-stage renal disease (ESRD), the body loses its ability to filter toxins and other molecules from the blood. Patients with ESRD undergo frequent visits to dialysis clinics, unless they are lucky enough to receive a kidney transplant, which itself requires a lifetime on immunosuppressant drugs.</p> <p>The Kidney Project’s device consists of a hemofilter that isolates toxins and other waste from the blood plus a bioreactor, containing live, engineered cells, that balances the composition of filtered blood. It is packaged into a proprietary, biologically neutral shell, precluding immune rejection as well as the need for immunosuppressant drugs, according to Roy.</p> <p>Moreover, its components are modular – the hemofilter could be implanted, on its own, to simplify the dialysis process, enabling dialysis to occur with a patient’s blood never leaving the body. And the shell that contains the device could be used to house other artificial organs in the future.</p> <p>“The Kidney Project would not be where it is today without our donors and advocates,” said Roy. “It is with their generosity and the continued support of our greater community we are able to receive this prize.”</p> <p>Millions of patients are desperate for more comfortable solutions to their condition.</p> <p>“The Kidney Project is building a more hopeful future for patients with no easy options,” said Kathy Giacomini, PhD, dean of the UCSF School of Pharmacy. “Funding like the Artificial Kidney Prize is vital for ensuring that this work makes good on its promise to revolutionize the treatment of kidney failure.”</p> <h2>More</h2> <p><a href="https://www.hhs.gov/about/news/2023/06/12/hhs-american-society-nephrology-announce-winners-9-2-million-artificial-kidney-prize-phase-2-kidneyx-summit.html">HHS and the American Society of Nephrology Announce Winners of $9.2 Million Artificial Kidney Prize Phase 2 at KidneyX Summit (U.S. Department of Health and Human Services)</a></p></div></div></div> </div> </div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-views-panes pane-news-page-panel-pane-3" > <h2 class="pane-title">Tags</h2> <div class="pane-content"> <div class="view view-news-page view-id-news_page view-display-id-panel_pane_3 view-dom-id-66723cde358baabbb0ec5910d6640f4f"> <div class="view-content"> <div> <div class="views-field views-field-field-keywords-revision-id"> <span class="views-label views-label-field-keywords-revision-id">Topics: </span> <div class="field-content"><a href="/topics-expertise/implantable-bioartificial-kidney" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">implantable bioartificial kidney</a>, <a href="/topics-expertise/kidney-project" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">The Kidney Project</a>, <a href="/topics-expertise/kidneyx" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">KidneyX</a></div> </div> <div class="views-field views-field-field-categories-revision-id"> <span class="views-label views-label-field-categories-revision-id">Category: </span> <div class="field-content"><a href="/categories/research" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Research</a>, <a href="/categories/honors-and-awards" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Honors and Awards</a></div> </div> <div class="views-field views-field-nothing"> <span class="views-label views-label-nothing">Sites: </span> <div class="field-content">School of Pharmacy, Department of Bioengineering and Therapeutic Sciences, PharmD Degree Program</div> </div> </div> </div> </div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-views-panes pane-related-profiles-news-related-profiles-pane" > <h2 class="pane-title">Related profiles</h2> <div class="pane-content"> <div class="view view-related-profiles view-id-related_profiles view-display-id-news_related_profiles_pane columns-4 view-dom-id-4d26ce4015e4bb62657a1f75d72d41b1"> <div class="view-content"> <div class="relatedprofile"> <span class="views-field views-field-field-person-headshot-photo"> <span class="field-content"><a href="https://pharmacy.ucsf.edu/shuvo-roy"><picture >  <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/person/photo/ucsf_20191203_roy_shuvo_397.jpg?itok=pckIE5ad&timestamp=1670440016 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_third/public/person/photo/ucsf_20191203_roy_shuvo_397.jpg?itok=VZJoZhnR&timestamp=1670440016 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_half/public/person/photo/ucsf_20191203_roy_shuvo_397.jpg?itok=iCX0OxqU&timestamp=1670440016 3x" media="(min-width: 1025px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/person/photo/ucsf_20191203_roy_shuvo_397.jpg?itok=pckIE5ad&timestamp=1670440016 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_quarter/public/person/photo/ucsf_20191203_roy_shuvo_397.jpg?itok=fYrurUCJ&timestamp=1670440016 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_half/public/person/photo/ucsf_20191203_roy_shuvo_397.jpg?itok=iCX0OxqU&timestamp=1670440016 3x" media="(min-width: 656px) and (max-width: 1024px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/person/photo/ucsf_20191203_roy_shuvo_397.jpg?itok=pckIE5ad&timestamp=1670440016 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_quarter/public/person/photo/ucsf_20191203_roy_shuvo_397.jpg?itok=fYrurUCJ&timestamp=1670440016 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_half/public/person/photo/ucsf_20191203_roy_shuvo_397.jpg?itok=iCX0OxqU&timestamp=1670440016 3x" media="(min-width: 481px) and (max-width: 655px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/person/photo/ucsf_20191203_roy_shuvo_397.jpg?itok=pckIE5ad&timestamp=1670440016 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_quarter/public/person/photo/ucsf_20191203_roy_shuvo_397.jpg?itok=fYrurUCJ&timestamp=1670440016 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_half/public/person/photo/ucsf_20191203_roy_shuvo_397.jpg?itok=iCX0OxqU&timestamp=1670440016 3x" media="(min-width: 431px) and (max-width: 480px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/person/photo/ucsf_20191203_roy_shuvo_397.jpg?itok=pckIE5ad&timestamp=1670440016 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_third/public/person/photo/ucsf_20191203_roy_shuvo_397.jpg?itok=VZJoZhnR&timestamp=1670440016 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_half/public/person/photo/ucsf_20191203_roy_shuvo_397.jpg?itok=iCX0OxqU&timestamp=1670440016 3x" media="(min-width: 0px) and (max-width: 430px)" />  <img src="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_half/public/person/photo/ucsf_20191203_roy_shuvo_397.jpg?itok=iCX0OxqU&timestamp=1670440016" alt="Shuvo Roy headshot" title="" /> </picture></a></span> </span> <div class="views-field views-field-path"> <span class="field-content"><a href="https://pharmacy.ucsf.edu/shuvo-roy">Shuvo Roy</a></span> </div> </div> </div> </div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-fieldable-panels-pane pane-current-171 pane-bundle-text" > <div class="pane-content"> <div class="fieldable-panels-pane"> <div class="field field-name-field-basic-text-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><hr /><p class="fine-print"><strong>About the School</strong>: The UCSF School of Pharmacy aims to solve the most pressing health care problems and strives to ensure that each patient receives the safest, most effective treatments. Our discoveries seed the development of novel therapies, and our researchers consistently lead the nation in NIH funding. The School’s doctor of pharmacy (PharmD) degree program, with its unique emphasis on scientific thinking, prepares students to be critical thinkers and leaders in their field.</p></div></div></div></div> </div> </div> </div> </div> <div class="burr-flipped-sidebar burr-flipped-content-region panel-panel"> <div class="burr-flipped-sidebar-inner burr-flipped-content-region-inner panel-panel-inner"> <div class="region region-sidebar region-background-callout"><div class="panel-pane pane-block pane-apachesolr-search-mlt-002 pane-basic" > <h2 class="pane-title">Related news</h2> <div class="pane-content"> <div class="item-list"><ul><li class="first"><a href="/news/2021/09/kidney-project-successfully-tests-prototype-bioartificial-kidney">The Kidney Project successfully tests a prototype bioartificial kidney</a></li> <li><a href="/news/2019/05/kidney-project-earns-kidneyx-award-make-home-dialysis-better-patients">The Kidney Project earns KidneyX award to make home dialysis better for patients</a></li> <li><a href="/news/2020/07/kidney-project-wins-kidneyx-award-enable-simpler-safer-home-dialysis">The Kidney Project wins KidneyX Award to enable simpler, safer at-home dialysis</a></li> <li><a href="/news/2020/10/bioartificial-kidney-aims-mimic-natural-kidney-function-1-million-grant-john-marcia">Bioartificial kidney aims to mimic natural kidney function with $1 million grant from the John and Marcia Goldman Foundation</a></li> <li class="last"><a href="/news/2012/10/artificial-kidney-project-receives-3-million-goldman-foundation-nih">Artificial kidney project receives $3 million from Goldman Foundation, NIH</a></li> </ul></div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-views-panes pane-openacademy-news-news-listing" > <h2 class="pane-title">Recent news</h2> <div class="pane-content"> <div class="view view-openacademy-news view-id-openacademy_news view-display-id-news_listing view-dom-id-348962892008481fde83b7ca2b528686"> <div 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views-row-3 views-row-odd views-row-last clearfix"> <div class="views-field views-field-rendered"> <span class="field-content"><a href="/news/2024/11/oni-orisan-tamraz-awarded-stripe-double-helix-award-contributions-pharmacogenomics"><picture >  <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_thumbnail/public/featured/oni-orisan_and_tamraz.jpg?itok=BEd7STEu&timestamp=1731708601 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/featured/oni-orisan_and_tamraz.jpg?itok=p2CJEN0c&timestamp=1731708601 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_quarter/public/featured/oni-orisan_and_tamraz.jpg?itok=k971xPLk&timestamp=1731708601 3x" media="(min-width: 1025px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_thumbnail/public/featured/oni-orisan_and_tamraz.jpg?itok=BEd7STEu&timestamp=1731708601 1x, 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/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/featured/oni-orisan_and_tamraz.jpg?itok=p2CJEN0c&timestamp=1731708601 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_quarter/public/featured/oni-orisan_and_tamraz.jpg?itok=k971xPLk&timestamp=1731708601 3x" media="(min-width: 431px) and (max-width: 480px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_thumbnail/public/featured/oni-orisan_and_tamraz.jpg?itok=BEd7STEu&timestamp=1731708601 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/featured/oni-orisan_and_tamraz.jpg?itok=p2CJEN0c&timestamp=1731708601 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_quarter/public/featured/oni-orisan_and_tamraz.jpg?itok=k971xPLk&timestamp=1731708601 3x" media="(min-width: 0px) and (max-width: 430px)" />  <img src="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_thumbnail/public/featured/oni-orisan_and_tamraz.jpg?itok=BEd7STEu&timestamp=1731708601" alt="Oni-Orisan and Tamraz" title="" /> </picture></a></span> </div> <div class="views-field views-field-title"> <span class="field-content"><a href="/news/2024/11/oni-orisan-tamraz-awarded-stripe-double-helix-award-contributions-pharmacogenomics">Oni-Orisan and Tamraz Awarded STRIPE Double Helix Award for Contributions to Pharmacogenomics</a></span> </div> <div class="views-field views-field-created"> <span class="field-content">Fri Nov 15, 2024</span> </div> </div> </div> <div class="view-footer"> <div class="more-link"><a href="/news">SEE ALL ></a></div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div>  </div>  </div>  </div>  </div>  <div role="complementary" class="footer-make-a-gift-and-quote"> <div class="footer-make-a-gift"> <a href="https://makeagift.ucsf.edu/site/SPageServer?pagename=A1_API_GeneralGivingForm&Primary=Pharmacy">Make a gift</a> </div> <div class="footer-quote"> Science is the foundation of the School of Pharmacy’s 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