CINXE.COM
Esophageal Cancer - Amira Software - Computed Tomography - Life in Atomic Resolution
<!DOCTYPE html> <html lang="en-US"> <head > <meta charset="UTF-8" /> <meta name="viewport" content="width=device-width, initial-scale=1" /> <meta name='robots' content='index, follow, max-image-preview:large, max-snippet:-1, max-video-preview:-1' /> <!-- This site is optimized with the Yoast SEO Premium plugin v23.4 (Yoast SEO v23.5) - https://yoast.com/wordpress/plugins/seo/ --> <title>Esophageal Cancer - Amira Software - Computed Tomography - Life in Atomic Resolution</title> <meta name="description" content="Esophageal cancer tumor volume is analyzed using Thermo Scientific Amira Software and computed tomography angiography." /> <link rel="canonical" href="https://www.thermofisher.com/blog/atomic-resolution/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer/" /> <meta property="og:locale" content="en_US" /> <meta property="og:type" content="article" /> <meta property="og:title" content="Tumor volume analysis with Amira Software assists in the diagnosis of esophageal cancer" /> <meta property="og:description" content="Esophageal cancer tumor volume is analyzed using Thermo Scientific Amira Software and computed tomography angiography." /> <meta property="og:url" content="https://www.thermofisher.com/blog/atomic-resolution/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer/" /> <meta property="og:site_name" content="Life in Atomic Resolution" /> <meta property="article:publisher" content="https://www.facebook.com/thermofisher" /> <meta property="article:published_time" content="2024-07-01T11:00:53+00:00" /> <meta property="article:modified_time" content="2024-07-10T22:01:53+00:00" /> <meta property="og:image" content="https://www.thermofisher.com/blog/atomic-resolution/wp-content/uploads/sites/22/2024/06/Tumor-Volume-Oesophageal-Cancer-Blog-Social-_no-logo__1200x630.jpg" /> <meta property="og:image:width" content="1200" /> <meta property="og:image:height" content="630" /> <meta property="og:image:type" content="image/jpeg" /> <meta name="author" content="Alex Ilitchev" /> <meta name="twitter:card" content="summary_large_image" /> <meta name="twitter:creator" content="@thermofisher" /> <meta name="twitter:site" content="@thermofisher" /> <meta name="twitter:label1" content="Written by" /> <meta name="twitter:data1" content="Alex Ilitchev" /> <meta name="twitter:label2" content="Est. reading time" /> <meta name="twitter:data2" content="3 minutes" /> <script type="application/ld+json" class="yoast-schema-graph">{"@context":"https://schema.org","@graph":[{"@type":"WebPage","@id":"https://www.thermofisher.com/blog/atomic-resolution/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer/","url":"https://www.thermofisher.com/blog/atomic-resolution/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer/","name":"Esophageal Cancer - Amira Software - Computed Tomography - Life in Atomic Resolution","isPartOf":{"@id":"https://www.thermofisher.com/blog/atomic-resolution/#website"},"primaryImageOfPage":{"@id":"https://www.thermofisher.com/blog/atomic-resolution/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer/#primaryimage"},"image":{"@id":"https://www.thermofisher.com/blog/atomic-resolution/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer/#primaryimage"},"thumbnailUrl":"https://www.thermofisher.com/blog/atomic-resolution/wp-content/uploads/sites/22/2024/06/Tumor-Volume-Oesophageal-Cancer-Blog-Social-_no-logo__1200x630.jpg","datePublished":"2024-07-01T11:00:53+00:00","dateModified":"2024-07-10T22:01:53+00:00","author":{"@id":"https://www.thermofisher.com/blog/atomic-resolution/#/schema/person/7b14b1ad2e6aaf9f989f5fb345363e39"},"description":"Esophageal cancer tumor volume is analyzed using Thermo Scientific Amira Software and computed tomography angiography.","breadcrumb":{"@id":"https://www.thermofisher.com/blog/atomic-resolution/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https://www.thermofisher.com/blog/atomic-resolution/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https://www.thermofisher.com/blog/atomic-resolution/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer/#primaryimage","url":"https://www.thermofisher.com/blog/atomic-resolution/wp-content/uploads/sites/22/2024/06/Tumor-Volume-Oesophageal-Cancer-Blog-Social-_no-logo__1200x630.jpg","contentUrl":"https://www.thermofisher.com/blog/atomic-resolution/wp-content/uploads/sites/22/2024/06/Tumor-Volume-Oesophageal-Cancer-Blog-Social-_no-logo__1200x630.jpg","width":1200,"height":630,"caption":"Tumor Volume Oesophageal Cancer"},{"@type":"BreadcrumbList","@id":"https://www.thermofisher.com/blog/atomic-resolution/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://www.thermofisher.com/blog/atomic-resolution/"},{"@type":"ListItem","position":2,"name":"Tumor volume analysis with Amira Software assists in the diagnosis of esophageal cancer"}]},{"@type":"WebSite","@id":"https://www.thermofisher.com/blog/atomic-resolution/#website","url":"https://www.thermofisher.com/blog/atomic-resolution/","name":"Life in Atomic Resolution","description":"Electron and cryo-electron microscopy stories and solutions about the advancement of cellular and structural biology","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https://www.thermofisher.com/blog/atomic-resolution/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https://www.thermofisher.com/blog/atomic-resolution/#/schema/person/7b14b1ad2e6aaf9f989f5fb345363e39","name":"Alex Ilitchev","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https://www.thermofisher.com/blog/atomic-resolution/#/schema/person/image/","url":"https://secure.gravatar.com/avatar/4b7f1ab8dd85e20f734eb34e834a9195?s=96&d=mm&r=g","contentUrl":"https://secure.gravatar.com/avatar/4b7f1ab8dd85e20f734eb34e834a9195?s=96&d=mm&r=g","caption":"Alex Ilitchev"},"sameAs":["https://www.thermofisher.com/blog/microscopy"],"url":"https://www.thermofisher.com/blog/author/alexilitchev/"}]}</script> <!-- / Yoast SEO Premium plugin. --> <link rel='dns-prefetch' href='//www.thermofisher.com' /> <link rel='dns-prefetch' href='//use.fontawesome.com' /> <link rel='dns-prefetch' href='//v0.wordpress.com' /> <link rel="alternate" type="application/rss+xml" title="Life in Atomic Resolution » Feed" href="https://www.thermofisher.com/blog/atomic-resolution/feed/" /> <link rel="alternate" type="application/rss+xml" title="Life in Atomic Resolution » Comments Feed" href="https://www.thermofisher.com/blog/atomic-resolution/comments/feed/" /> <link rel="alternate" type="application/rss+xml" title="Life in Atomic Resolution » Tumor volume analysis with Amira Software assists in the diagnosis of esophageal cancer Comments Feed" href="https://www.thermofisher.com/blog/atomic-resolution/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer/feed/" /> <!-- Optimizely tracking code --> <script src="https://cdn.optimizely.com/js/8156647427.js"></script> <!-- Hotjar Tracking Code for https://www.thermofisher.com/blog --> <script> (function(h,o,t,j,a,r){ h.hj=h.hj||function(){(h.hj.q=h.hj.q||[]).push(arguments)}; h._hjSettings={hjid:373708,hjsv:5}; a=o.getElementsByTagName('head')[0]; r=o.createElement('script');r.async=1; r.src=t+h._hjSettings.hjid+j+h._hjSettings.hjsv; a.appendChild(r); })(window,document,'//static.hotjar.com/c/hotjar-','.js?sv='); </script> <!-- This site uses the Google Analytics by MonsterInsights plugin v9.2.0 - Using Analytics tracking - https://www.monsterinsights.com/ --> <script src="//www.googletagmanager.com/gtag/js?id=G-TJ18KZWFVE" data-cfasync="false" data-wpfc-render="false" type="text/javascript" async></script> <script data-cfasync="false" data-wpfc-render="false" type="text/javascript"> var mi_version = '9.2.0'; var mi_track_user = true; var mi_no_track_reason = ''; var MonsterInsightsDefaultLocations = {"page_location":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\/"}; if ( typeof MonsterInsightsPrivacyGuardFilter === 'function' ) { var MonsterInsightsLocations = (typeof MonsterInsightsExcludeQuery === 'object') ? MonsterInsightsPrivacyGuardFilter( MonsterInsightsExcludeQuery ) : MonsterInsightsPrivacyGuardFilter( MonsterInsightsDefaultLocations ); } else { var MonsterInsightsLocations = (typeof MonsterInsightsExcludeQuery === 'object') ? MonsterInsightsExcludeQuery : MonsterInsightsDefaultLocations; } var disableStrs = [ 'ga-disable-G-TJ18KZWFVE', ]; /* Function to detect opted out users */ function __gtagTrackerIsOptedOut() { for (var index = 0; index < disableStrs.length; index++) { if (document.cookie.indexOf(disableStrs[index] + '=true') > -1) { return true; } } return false; } /* Disable tracking if the opt-out cookie exists. */ if (__gtagTrackerIsOptedOut()) { for (var index = 0; index < disableStrs.length; index++) { window[disableStrs[index]] = true; } } /* Opt-out function */ function __gtagTrackerOptout() { for (var index = 0; index < disableStrs.length; index++) { document.cookie = disableStrs[index] + '=true; expires=Thu, 31 Dec 2099 23:59:59 UTC; path=/'; window[disableStrs[index]] = true; } } if ('undefined' === typeof gaOptout) { function gaOptout() { __gtagTrackerOptout(); } } window.dataLayer = window.dataLayer || []; window.MonsterInsightsDualTracker = { helpers: {}, trackers: {}, }; if (mi_track_user) { function __gtagDataLayer() { dataLayer.push(arguments); } function __gtagTracker(type, name, parameters) { if (!parameters) { parameters = {}; } if (parameters.send_to) { __gtagDataLayer.apply(null, arguments); return; } if (type === 'event') { parameters.send_to = monsterinsights_frontend.v4_id; var hookName = name; if (typeof parameters['event_category'] !== 'undefined') { hookName = parameters['event_category'] + ':' + name; } if (typeof MonsterInsightsDualTracker.trackers[hookName] !== 'undefined') { MonsterInsightsDualTracker.trackers[hookName](parameters); } else { __gtagDataLayer('event', name, parameters); } } else { __gtagDataLayer.apply(null, arguments); } } __gtagTracker('js', new Date()); __gtagTracker('set', { 'developer_id.dZGIzZG': true, }); if ( MonsterInsightsLocations.page_location ) { __gtagTracker('set', MonsterInsightsLocations); } __gtagTracker('config', 'G-TJ18KZWFVE', {"use_amp_client_id":"true","forceSSL":"true","link_attribution":"true"} ); window.gtag = __gtagTracker; (function () { /* https://developers.google.com/analytics/devguides/collection/analyticsjs/ */ /* ga and __gaTracker compatibility shim. */ var noopfn = function () { return null; }; var newtracker = function () { return new Tracker(); }; var Tracker = function () { return null; }; var p = Tracker.prototype; p.get = noopfn; p.set = noopfn; p.send = function () { var args = Array.prototype.slice.call(arguments); args.unshift('send'); __gaTracker.apply(null, args); }; var __gaTracker = function () { var len = arguments.length; if (len === 0) { return; } var f = arguments[len - 1]; if (typeof f !== 'object' || f === null || typeof f.hitCallback !== 'function') { if ('send' === arguments[0]) { var hitConverted, hitObject = false, action; if ('event' === arguments[1]) { if ('undefined' !== typeof arguments[3]) { hitObject = { 'eventAction': arguments[3], 'eventCategory': arguments[2], 'eventLabel': arguments[4], 'value': arguments[5] ? arguments[5] : 1, } } } if ('pageview' === arguments[1]) { if ('undefined' !== typeof arguments[2]) { hitObject = { 'eventAction': 'page_view', 'page_path': arguments[2], } } } if (typeof arguments[2] === 'object') { hitObject = arguments[2]; } if (typeof arguments[5] === 'object') { Object.assign(hitObject, arguments[5]); } if ('undefined' !== typeof arguments[1].hitType) { hitObject = arguments[1]; if ('pageview' === hitObject.hitType) { hitObject.eventAction = 'page_view'; } } if (hitObject) { action = 'timing' === arguments[1].hitType ? 'timing_complete' : hitObject.eventAction; hitConverted = mapArgs(hitObject); __gtagTracker('event', action, hitConverted); } } return; } function mapArgs(args) { var arg, hit = {}; var gaMap = { 'eventCategory': 'event_category', 'eventAction': 'event_action', 'eventLabel': 'event_label', 'eventValue': 'event_value', 'nonInteraction': 'non_interaction', 'timingCategory': 'event_category', 'timingVar': 'name', 'timingValue': 'value', 'timingLabel': 'event_label', 'page': 'page_path', 'location': 'page_location', 'title': 'page_title', 'referrer' : 'page_referrer', }; for (arg in args) { if (!(!args.hasOwnProperty(arg) || !gaMap.hasOwnProperty(arg))) { hit[gaMap[arg]] = args[arg]; } else { hit[arg] = args[arg]; } } return hit; } try { f.hitCallback(); } catch (ex) { } }; __gaTracker.create = newtracker; __gaTracker.getByName = newtracker; __gaTracker.getAll = function () { return []; }; __gaTracker.remove = noopfn; __gaTracker.loaded = true; window['__gaTracker'] = __gaTracker; })(); } else { console.log(""); (function () { function __gtagTracker() { return null; } window['__gtagTracker'] = __gtagTracker; window['gtag'] = __gtagTracker; })(); } </script> <!-- / Google Analytics by MonsterInsights --> <link rel='stylesheet' id='jetpack_related-posts-css' href='https://www.thermofisher.com/blog/atomic-resolution/wp-content/plugins/jetpack/modules/related-posts/related-posts.css?ver=20240116' type='text/css' media='all' /> <link rel='stylesheet' id='accelerating-science-blogs-css' href='https://www.thermofisher.com/blog/atomic-resolution/wp-content/themes/accelerating-science-blogs/style.css?ver=1.2.9.3' type='text/css' media='all' /> <link rel='stylesheet' id='wp-block-library-css' href='https://www.thermofisher.com/blog//wp-includes/css/dist/block-library/style.min.css?ver=6.6.1' type='text/css' media='all' /> <link rel='stylesheet' id='mediaelement-css' href='https://www.thermofisher.com/blog//wp-includes/js/mediaelement/mediaelementplayer-legacy.min.css?ver=4.2.17' type='text/css' media='all' /> <link rel='stylesheet' id='wp-mediaelement-css' href='https://www.thermofisher.com/blog//wp-includes/js/mediaelement/wp-mediaelement.min.css?ver=6.6.1' type='text/css' media='all' /> <style id='jetpack-sharing-buttons-style-inline-css' type='text/css'> .jetpack-sharing-buttons__services-list{display:flex;flex-direction:row;flex-wrap:wrap;gap:0;list-style-type:none;margin:5px;padding:0}.jetpack-sharing-buttons__services-list.has-small-icon-size{font-size:12px}.jetpack-sharing-buttons__services-list.has-normal-icon-size{font-size:16px}.jetpack-sharing-buttons__services-list.has-large-icon-size{font-size:24px}.jetpack-sharing-buttons__services-list.has-huge-icon-size{font-size:36px}@media print{.jetpack-sharing-buttons__services-list{display:none!important}}.editor-styles-wrapper .wp-block-jetpack-sharing-buttons{gap:0;padding-inline-start:0}ul.jetpack-sharing-buttons__services-list.has-background{padding:1.25em 2.375em} </style> <style id='classic-theme-styles-inline-css' type='text/css'> /*! This file is auto-generated */ .wp-block-button__link{color:#fff;background-color:#32373c;border-radius:9999px;box-shadow:none;text-decoration:none;padding:calc(.667em + 2px) calc(1.333em + 2px);font-size:1.125em}.wp-block-file__button{background:#32373c;color:#fff;text-decoration:none} </style> <style id='global-styles-inline-css' type='text/css'> :root{--wp--preset--aspect-ratio--square: 1;--wp--preset--aspect-ratio--4-3: 4/3;--wp--preset--aspect-ratio--3-4: 3/4;--wp--preset--aspect-ratio--3-2: 3/2;--wp--preset--aspect-ratio--2-3: 2/3;--wp--preset--aspect-ratio--16-9: 16/9;--wp--preset--aspect-ratio--9-16: 9/16;--wp--preset--color--black: #000000;--wp--preset--color--cyan-bluish-gray: #abb8c3;--wp--preset--color--white: #ffffff;--wp--preset--color--pale-pink: #f78da7;--wp--preset--color--vivid-red: #cf2e2e;--wp--preset--color--luminous-vivid-orange: #ff6900;--wp--preset--color--luminous-vivid-amber: #fcb900;--wp--preset--color--light-green-cyan: #7bdcb5;--wp--preset--color--vivid-green-cyan: #00d084;--wp--preset--color--pale-cyan-blue: #8ed1fc;--wp--preset--color--vivid-cyan-blue: #0693e3;--wp--preset--color--vivid-purple: #9b51e0;--wp--preset--gradient--vivid-cyan-blue-to-vivid-purple: linear-gradient(135deg,rgba(6,147,227,1) 0%,rgb(155,81,224) 100%);--wp--preset--gradient--light-green-cyan-to-vivid-green-cyan: linear-gradient(135deg,rgb(122,220,180) 0%,rgb(0,208,130) 100%);--wp--preset--gradient--luminous-vivid-amber-to-luminous-vivid-orange: linear-gradient(135deg,rgba(252,185,0,1) 0%,rgba(255,105,0,1) 100%);--wp--preset--gradient--luminous-vivid-orange-to-vivid-red: linear-gradient(135deg,rgba(255,105,0,1) 0%,rgb(207,46,46) 100%);--wp--preset--gradient--very-light-gray-to-cyan-bluish-gray: linear-gradient(135deg,rgb(238,238,238) 0%,rgb(169,184,195) 100%);--wp--preset--gradient--cool-to-warm-spectrum: linear-gradient(135deg,rgb(74,234,220) 0%,rgb(151,120,209) 20%,rgb(207,42,186) 40%,rgb(238,44,130) 60%,rgb(251,105,98) 80%,rgb(254,248,76) 100%);--wp--preset--gradient--blush-light-purple: linear-gradient(135deg,rgb(255,206,236) 0%,rgb(152,150,240) 100%);--wp--preset--gradient--blush-bordeaux: linear-gradient(135deg,rgb(254,205,165) 0%,rgb(254,45,45) 50%,rgb(107,0,62) 100%);--wp--preset--gradient--luminous-dusk: linear-gradient(135deg,rgb(255,203,112) 0%,rgb(199,81,192) 50%,rgb(65,88,208) 100%);--wp--preset--gradient--pale-ocean: linear-gradient(135deg,rgb(255,245,203) 0%,rgb(182,227,212) 50%,rgb(51,167,181) 100%);--wp--preset--gradient--electric-grass: linear-gradient(135deg,rgb(202,248,128) 0%,rgb(113,206,126) 100%);--wp--preset--gradient--midnight: linear-gradient(135deg,rgb(2,3,129) 0%,rgb(40,116,252) 100%);--wp--preset--font-size--small: 13px;--wp--preset--font-size--medium: 20px;--wp--preset--font-size--large: 36px;--wp--preset--font-size--x-large: 42px;--wp--preset--spacing--20: 0.44rem;--wp--preset--spacing--30: 0.67rem;--wp--preset--spacing--40: 1rem;--wp--preset--spacing--50: 1.5rem;--wp--preset--spacing--60: 2.25rem;--wp--preset--spacing--70: 3.38rem;--wp--preset--spacing--80: 5.06rem;--wp--preset--shadow--natural: 6px 6px 9px rgba(0, 0, 0, 0.2);--wp--preset--shadow--deep: 12px 12px 50px rgba(0, 0, 0, 0.4);--wp--preset--shadow--sharp: 6px 6px 0px rgba(0, 0, 0, 0.2);--wp--preset--shadow--outlined: 6px 6px 0px -3px rgba(255, 255, 255, 1), 6px 6px rgba(0, 0, 0, 1);--wp--preset--shadow--crisp: 6px 6px 0px rgba(0, 0, 0, 1);}:where(.is-layout-flex){gap: 0.5em;}:where(.is-layout-grid){gap: 0.5em;}body .is-layout-flex{display: flex;}.is-layout-flex{flex-wrap: wrap;align-items: center;}.is-layout-flex > :is(*, div){margin: 0;}body .is-layout-grid{display: grid;}.is-layout-grid > :is(*, div){margin: 0;}:where(.wp-block-columns.is-layout-flex){gap: 2em;}:where(.wp-block-columns.is-layout-grid){gap: 2em;}:where(.wp-block-post-template.is-layout-flex){gap: 1.25em;}:where(.wp-block-post-template.is-layout-grid){gap: 1.25em;}.has-black-color{color: var(--wp--preset--color--black) !important;}.has-cyan-bluish-gray-color{color: var(--wp--preset--color--cyan-bluish-gray) !important;}.has-white-color{color: var(--wp--preset--color--white) !important;}.has-pale-pink-color{color: var(--wp--preset--color--pale-pink) !important;}.has-vivid-red-color{color: var(--wp--preset--color--vivid-red) !important;}.has-luminous-vivid-orange-color{color: var(--wp--preset--color--luminous-vivid-orange) !important;}.has-luminous-vivid-amber-color{color: var(--wp--preset--color--luminous-vivid-amber) !important;}.has-light-green-cyan-color{color: var(--wp--preset--color--light-green-cyan) !important;}.has-vivid-green-cyan-color{color: var(--wp--preset--color--vivid-green-cyan) !important;}.has-pale-cyan-blue-color{color: var(--wp--preset--color--pale-cyan-blue) !important;}.has-vivid-cyan-blue-color{color: var(--wp--preset--color--vivid-cyan-blue) !important;}.has-vivid-purple-color{color: var(--wp--preset--color--vivid-purple) !important;}.has-black-background-color{background-color: var(--wp--preset--color--black) !important;}.has-cyan-bluish-gray-background-color{background-color: var(--wp--preset--color--cyan-bluish-gray) !important;}.has-white-background-color{background-color: var(--wp--preset--color--white) !important;}.has-pale-pink-background-color{background-color: var(--wp--preset--color--pale-pink) !important;}.has-vivid-red-background-color{background-color: var(--wp--preset--color--vivid-red) !important;}.has-luminous-vivid-orange-background-color{background-color: var(--wp--preset--color--luminous-vivid-orange) !important;}.has-luminous-vivid-amber-background-color{background-color: var(--wp--preset--color--luminous-vivid-amber) !important;}.has-light-green-cyan-background-color{background-color: var(--wp--preset--color--light-green-cyan) !important;}.has-vivid-green-cyan-background-color{background-color: var(--wp--preset--color--vivid-green-cyan) !important;}.has-pale-cyan-blue-background-color{background-color: var(--wp--preset--color--pale-cyan-blue) !important;}.has-vivid-cyan-blue-background-color{background-color: var(--wp--preset--color--vivid-cyan-blue) !important;}.has-vivid-purple-background-color{background-color: var(--wp--preset--color--vivid-purple) !important;}.has-black-border-color{border-color: var(--wp--preset--color--black) !important;}.has-cyan-bluish-gray-border-color{border-color: var(--wp--preset--color--cyan-bluish-gray) !important;}.has-white-border-color{border-color: var(--wp--preset--color--white) !important;}.has-pale-pink-border-color{border-color: var(--wp--preset--color--pale-pink) !important;}.has-vivid-red-border-color{border-color: var(--wp--preset--color--vivid-red) !important;}.has-luminous-vivid-orange-border-color{border-color: var(--wp--preset--color--luminous-vivid-orange) !important;}.has-luminous-vivid-amber-border-color{border-color: var(--wp--preset--color--luminous-vivid-amber) !important;}.has-light-green-cyan-border-color{border-color: var(--wp--preset--color--light-green-cyan) !important;}.has-vivid-green-cyan-border-color{border-color: var(--wp--preset--color--vivid-green-cyan) !important;}.has-pale-cyan-blue-border-color{border-color: var(--wp--preset--color--pale-cyan-blue) !important;}.has-vivid-cyan-blue-border-color{border-color: var(--wp--preset--color--vivid-cyan-blue) !important;}.has-vivid-purple-border-color{border-color: var(--wp--preset--color--vivid-purple) !important;}.has-vivid-cyan-blue-to-vivid-purple-gradient-background{background: var(--wp--preset--gradient--vivid-cyan-blue-to-vivid-purple) !important;}.has-light-green-cyan-to-vivid-green-cyan-gradient-background{background: var(--wp--preset--gradient--light-green-cyan-to-vivid-green-cyan) !important;}.has-luminous-vivid-amber-to-luminous-vivid-orange-gradient-background{background: var(--wp--preset--gradient--luminous-vivid-amber-to-luminous-vivid-orange) !important;}.has-luminous-vivid-orange-to-vivid-red-gradient-background{background: var(--wp--preset--gradient--luminous-vivid-orange-to-vivid-red) !important;}.has-very-light-gray-to-cyan-bluish-gray-gradient-background{background: var(--wp--preset--gradient--very-light-gray-to-cyan-bluish-gray) !important;}.has-cool-to-warm-spectrum-gradient-background{background: var(--wp--preset--gradient--cool-to-warm-spectrum) !important;}.has-blush-light-purple-gradient-background{background: var(--wp--preset--gradient--blush-light-purple) !important;}.has-blush-bordeaux-gradient-background{background: var(--wp--preset--gradient--blush-bordeaux) !important;}.has-luminous-dusk-gradient-background{background: var(--wp--preset--gradient--luminous-dusk) !important;}.has-pale-ocean-gradient-background{background: var(--wp--preset--gradient--pale-ocean) !important;}.has-electric-grass-gradient-background{background: var(--wp--preset--gradient--electric-grass) !important;}.has-midnight-gradient-background{background: var(--wp--preset--gradient--midnight) !important;}.has-small-font-size{font-size: var(--wp--preset--font-size--small) !important;}.has-medium-font-size{font-size: var(--wp--preset--font-size--medium) !important;}.has-large-font-size{font-size: var(--wp--preset--font-size--large) !important;}.has-x-large-font-size{font-size: var(--wp--preset--font-size--x-large) !important;} :where(.wp-block-post-template.is-layout-flex){gap: 1.25em;}:where(.wp-block-post-template.is-layout-grid){gap: 1.25em;} :where(.wp-block-columns.is-layout-flex){gap: 2em;}:where(.wp-block-columns.is-layout-grid){gap: 2em;} :root :where(.wp-block-pullquote){font-size: 1.5em;line-height: 1.6;} </style> <link rel='stylesheet' id='gforms_reset_css-css' href='https://www.thermofisher.com/blog/atomic-resolution/wp-content/plugins/gravityforms/legacy/css/formreset.min.css?ver=2.8.17' type='text/css' media='all' /> <link rel='stylesheet' id='gforms_formsmain_css-css' href='https://www.thermofisher.com/blog/atomic-resolution/wp-content/plugins/gravityforms/legacy/css/formsmain.min.css?ver=2.8.17' type='text/css' media='all' /> <link rel='stylesheet' id='gforms_ready_class_css-css' href='https://www.thermofisher.com/blog/atomic-resolution/wp-content/plugins/gravityforms/legacy/css/readyclass.min.css?ver=2.8.17' type='text/css' media='all' /> <link rel='stylesheet' id='gforms_browsers_css-css' href='https://www.thermofisher.com/blog/atomic-resolution/wp-content/plugins/gravityforms/legacy/css/browsers.min.css?ver=2.8.17' type='text/css' media='all' /> <link rel='stylesheet' id='globals-css' href='https://www.thermofisher.com/blog/atomic-resolution/wp-content/themes/accelerating-science-blogs/global-style.css?ver=1.2.9.3' type='text/css' media='all' /> <link rel='stylesheet' id='bfa-font-awesome-css' href='https://use.fontawesome.com/releases/v5.15.4/css/all.css?ver=2.0.3' type='text/css' media='all' /> <script type="text/javascript" id="jetpack_related-posts-js-extra"> /* <![CDATA[ */ var related_posts_js_options = {"post_heading":"h4"}; /* ]]> */ </script> <script type="text/javascript" src="https://www.thermofisher.com/blog/atomic-resolution/wp-content/plugins/jetpack/_inc/build/related-posts/related-posts.min.js?ver=20240116" id="jetpack_related-posts-js"></script> <script type="text/javascript" src="https://www.thermofisher.com/blog/atomic-resolution/wp-content/plugins/google-analytics-premium/assets/js/frontend-gtag.min.js?ver=9.2.0" id="monsterinsights-frontend-script-js" async="async" data-wp-strategy="async"></script> <script data-cfasync="false" data-wpfc-render="false" type="text/javascript" id='monsterinsights-frontend-script-js-extra'>/* <![CDATA[ */ var monsterinsights_frontend = {"js_events_tracking":"true","download_extensions":"doc,pdf,ppt,zip,xls,docx,pptx,xlsx","inbound_paths":"[{\"path\":\"\\\/go\\\/\",\"label\":\"affiliate\"},{\"path\":\"\\\/recommend\\\/\",\"label\":\"affiliate\"}]","home_url":"https:\/\/admin.acceleratingscience.com\/atomic-resolution","hash_tracking":"false","v4_id":"G-TJ18KZWFVE"};/* ]]> */ </script> <script type="text/javascript" src="https://www.thermofisher.com/blog//wp-includes/js/jquery/jquery.min.js?ver=3.7.1" id="jquery-core-js"></script> <script type="text/javascript" src="https://www.thermofisher.com/blog//wp-includes/js/jquery/jquery-migrate.min.js?ver=3.4.1" id="jquery-migrate-js"></script> <script type="text/javascript" src="https://www.thermofisher.com/blog/atomic-resolution/wp-content/plugins/mashshare-google-analytics/assets/js/mashga.min.js?ver=1.0.9" id="mashga-js"></script> <script type="text/javascript" src="https://www.thermofisher.com/blog//wp-includes/js/underscore.min.js?ver=1.13.4" id="underscore-js"></script> <script type="text/javascript" src="https://www.thermofisher.com/blog//wp-includes/js/backbone.min.js?ver=1.5.0" id="backbone-js"></script> <script type="text/javascript" id="wp-api-js-js-extra"> /* <![CDATA[ */ var WP_API_Settings = {"root":"https:\/\/admin.acceleratingscience.com\/atomic-resolution","nonce":"8e838958fa"}; /* ]]> */ </script> <script type="text/javascript" src="https://www.thermofisher.com/blog/atomic-resolution/wp-content/plugins/wp-search-live/public/assets/js/util--wp-api.js?ver=0.9" id="wp-api-js-js"></script> <script type="text/javascript" defer='defer' src="https://www.thermofisher.com/blog/atomic-resolution/wp-content/plugins/gravityforms/js/jquery.json.min.js?ver=2.8.17" id="gform_json-js"></script> <script type="text/javascript" id="gform_gravityforms-js-extra"> /* <![CDATA[ */ var gf_global = {"gf_currency_config":{"name":"U.S. Dollar","symbol_left":"$","symbol_right":"","symbol_padding":"","thousand_separator":",","decimal_separator":".","decimals":2,"code":"USD"},"base_url":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/plugins\/gravityforms","number_formats":[],"spinnerUrl":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/plugins\/gravityforms\/images\/spinner.svg","version_hash":"4a792b070322e711c2521ee9802c04ea","strings":{"newRowAdded":"New row added.","rowRemoved":"Row removed","formSaved":"The form has been saved. The content contains the link to return and complete the form."}}; var gf_global = {"gf_currency_config":{"name":"U.S. Dollar","symbol_left":"$","symbol_right":"","symbol_padding":"","thousand_separator":",","decimal_separator":".","decimals":2,"code":"USD"},"base_url":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/plugins\/gravityforms","number_formats":[],"spinnerUrl":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/plugins\/gravityforms\/images\/spinner.svg","version_hash":"4a792b070322e711c2521ee9802c04ea","strings":{"newRowAdded":"New row added.","rowRemoved":"Row removed","formSaved":"The form has been saved. The content contains the link to return and complete the form."}}; var gform_i18n = {"datepicker":{"days":{"monday":"Mo","tuesday":"Tu","wednesday":"We","thursday":"Th","friday":"Fr","saturday":"Sa","sunday":"Su"},"months":{"january":"January","february":"February","march":"March","april":"April","may":"May","june":"June","july":"July","august":"August","september":"September","october":"October","november":"November","december":"December"},"firstDay":1,"iconText":"Select date"}}; var gf_legacy_multi = {"":"1"}; var gform_gravityforms = {"strings":{"invalid_file_extension":"This type of file is not allowed. Must be one of the following:","delete_file":"Delete this file","in_progress":"in progress","file_exceeds_limit":"File exceeds size limit","illegal_extension":"This type of file is not allowed.","max_reached":"Maximum number of files reached","unknown_error":"There was a problem while saving the file on the server","currently_uploading":"Please wait for the uploading to complete","cancel":"Cancel","cancel_upload":"Cancel this upload","cancelled":"Cancelled"},"vars":{"images_url":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/plugins\/gravityforms\/images"}}; /* ]]> */ </script> <script type="text/javascript" id="gform_gravityforms-js-before"> /* <![CDATA[ */ var gform;gform||(document.addEventListener("gform_main_scripts_loaded",function(){gform.scriptsLoaded=!0}),window.addEventListener("DOMContentLoaded",function(){gform.domLoaded=!0}),gform={domLoaded:!1,scriptsLoaded:!1,initializeOnLoaded:function(o){gform.domLoaded&&gform.scriptsLoaded?o():!gform.domLoaded&&gform.scriptsLoaded?window.addEventListener("DOMContentLoaded",o):document.addEventListener("gform_main_scripts_loaded",o)},hooks:{action:{},filter:{}},addAction:function(o,n,r,t){gform.addHook("action",o,n,r,t)},addFilter:function(o,n,r,t){gform.addHook("filter",o,n,r,t)},doAction:function(o){gform.doHook("action",o,arguments)},applyFilters:function(o){return gform.doHook("filter",o,arguments)},removeAction:function(o,n){gform.removeHook("action",o,n)},removeFilter:function(o,n,r){gform.removeHook("filter",o,n,r)},addHook:function(o,n,r,t,i){null==gform.hooks[o][n]&&(gform.hooks[o][n]=[]);var e=gform.hooks[o][n];null==i&&(i=n+"_"+e.length),gform.hooks[o][n].push({tag:i,callable:r,priority:t=null==t?10:t})},doHook:function(n,o,r){var t;if(r=Array.prototype.slice.call(r,1),null!=gform.hooks[n][o]&&((o=gform.hooks[n][o]).sort(function(o,n){return o.priority-n.priority}),o.forEach(function(o){"function"!=typeof(t=o.callable)&&(t=window[t]),"action"==n?t.apply(null,r):r[0]=t.apply(null,r)})),"filter"==n)return r[0]},removeHook:function(o,n,t,i){var r;null!=gform.hooks[o][n]&&(r=(r=gform.hooks[o][n]).filter(function(o,n,r){return!!(null!=i&&i!=o.tag||null!=t&&t!=o.priority)}),gform.hooks[o][n]=r)}}); /* ]]> */ </script> <script type="text/javascript" defer='defer' src="https://www.thermofisher.com/blog/atomic-resolution/wp-content/plugins/gravityforms/js/gravityforms.min.js?ver=2.8.17" id="gform_gravityforms-js"></script> <script type="text/javascript" defer='defer' src="https://www.thermofisher.com/blog/atomic-resolution/wp-content/plugins/gravityforms/assets/js/dist/utils.min.js?ver=50c7bea9c2320e16728e44ae9fde5f26" id="gform_gravityforms_utils-js"></script> <script type="text/javascript" src="https://www.thermofisher.com/blog/atomic-resolution/wp-content/themes/accelerating-science-blogs/js/single-scripts.js?ver=1.2.9.3" id="single-scripts-js"></script> <link rel="https://api.w.org/" href="https://www.thermofisher.com/blog/atomic-resolution/wp-json/" /><link rel="alternate" title="JSON" type="application/json" href="https://www.thermofisher.com/blog/atomic-resolution/wp-json/wp/v2/posts/1461" /><link rel="EditURI" type="application/rsd+xml" title="RSD" href="https://www.thermofisher.com/blog/xmlrpc.php?rsd" /> <link rel='shortlink' href='https://www.thermofisher.com/blog/atomic-resolution/?p=1461' /> <link rel="alternate" title="oEmbed (JSON)" type="application/json+oembed" href="https://www.thermofisher.com/blog/atomic-resolution/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww.thermofisher.com%2Fblog%2Fatomic-resolution%2Ftumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer%2F" /> <link rel="alternate" title="oEmbed (XML)" type="text/xml+oembed" href="https://www.thermofisher.com/blog/atomic-resolution/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww.thermofisher.com%2Fblog%2Fatomic-resolution%2Ftumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer%2F&format=xml" /> <meta property="ia:markup_url" content="https://www.thermofisher.com/blog/atomic-resolution/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer/?ia_markup=1" /> <!-- Stream WordPress user activity plugin v4.0.2 --> <link rel="icon" href="https://www.thermofisher.com/blog/atomic-resolution/wp-content/themes/accelerating-science-blogs/images/favicon.ico" /> <link rel="pingback" href="https://www.thermofisher.com/blog/xmlrpc.php" /> <script type="application/ld+json"> {"@context":"http:\/\/schema.org","@type":"BlogPosting","mainEntityofPage":{"@type":"WebPage","@id":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\/"},"headline":"Tumor volume analysis with Amira Software assists in the diagnosis of esophageal cancer","datePublished":"07\/01\/2024","dateModified":"07\/01\/2024","publisher":{"@type":"Organization","name":"Thermo Fisher Scientific","URL":"https:\/\/www.thermofisher.com\/us\/en\/home.html","logo":{"@type":"ImageObject","url":"https:\/\/www.thermofisher.com\/content\/dam\/LifeTech\/Images\/Header\/logo-color.png"}},"image":{"@type":"ImageObject","url":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2024\/06\/Tumor-Volume-Oesophageal-Cancer-Blog-Social-_no-logo__1200x630.jpg","width":1200,"height":630},"author":{"@type":"Person","name":"Alex Ilitchev"}} </script> <script type="text/javascript" src="https://www.thermofisher.com/etc/designs/lifetech/clientlibs/digitaldata.js" defer="defer"></script> <script id="tagmanager" type="text/javascript" src='https://assets.adobedtm.com/launch-ENeecb77f1160a4928a492ff040f7110c7.min.js' defer="defer"></script> <script> (function($) { $(document).ready(function() { digitalData.setPageType('blog'); }) })(jQuery); </script> </head> <body class="post-template-default single single-post postid-1461 single-format-standard header-image full-width-content genesis-breadcrumbs-visible"><div class="site-container"><header class="site-header"><div class="wrap"><div class="title-area"><p class="site-title"><a href="https://www.thermofisher.com/" title="Thermo Fisher Scientific">Thermo Fisher Scientific</a></p><p class="site-description">Electron and cryo-electron microscopy stories and solutions about the advancement of cellular and structural biology</p></div><div class="widget-area header-widget-area"><section id="block-5" class="widget widget_block"><div class="widget-wrap"> <div class="wp-block-group"><div class="wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow"></div></div> </div></section> <section id="block-6" class="widget widget_block"><div class="widget-wrap"> <div class="wp-block-group"><div class="wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow"></div></div> </div></section> </div><div class="breadcrumb"><span class="breadcrumb-link-wrap"><a href="https://www.thermofisher.com/blog/?">Accelerating Science</a></span><span class="breadcrumb-link-wrap"><a class="breadcrumb-link" href="https://www.thermofisher.com/blog/atomic-resolution/"><span class="breadcrumb-link-text-wrap">Life in Atomic Resolution</span></a><meta ></span> <span aria-label="breadcrumb separator">/</span> <span class="breadcrumb-link-wrap"><a class="breadcrumb-link" href="https://www.thermofisher.com/blog/atomic-resolution/cryo-electron-microscopy-cryo-em/"><span class="breadcrumb-link-text-wrap">Cryo-Electron Microscopy (Cryo-EM)</span></a><meta ></span> <span aria-label="breadcrumb separator">/</span> <span class="breadcrumb-link-wrap"><a class="breadcrumb-link" href="https://www.thermofisher.com/blog/atomic-resolution/cryo-electron-microscopy-cryo-em/amira-software/"><span class="breadcrumb-link-text-wrap">Amira Software</span></a><meta ></span> <span aria-label="breadcrumb separator">/</span> <span class="breadcrumb-current-title">Tumor volume analysis with Amira Software assists in the diagnosis of esophageal cancer</span></div></div></header> <section class="hero-banner" style="background-image:url(https://www.thermofisher.com/blog/atomic-resolution/wp-content/uploads/sites/22/2024/07/Tumor-Volume-Oesophageal-Cancer-Blog-Header_ALT_1920x800.jpg)"> </section> <div class="site-inner"><div class="content-sidebar-wrap"><main class="content"><article class="post-1461 post type-post status-publish format-standard has-post-thumbnail category-amira-software category-cancer-research category-cryo-electron-microscopy-software category-cryo-electron-microscopy-cryo-em entry" aria-label="Tumor volume analysis with Amira Software assists in the diagnosis of esophageal cancer"><header class="entry-header"><h1 class="entry-title">Tumor volume analysis with Amira Software assists in the diagnosis of esophageal cancer</h1> <span class="post-info-author"> By <a href="https://www.thermofisher.com/blog/author/alexilitchev/" title="Posts by Alex Ilitchev" rel="author">Alex Ilitchev</a> </span> <span class="post-info-date"> 07.01.2024 </span> </header><div class="entry-content"><h2 style="font-size: 100%"><strong>Clinical challenges of esophageal cancer diagnosis </strong></h2> <p>Esophageal cancer is a challenging and dangerous disease, accounting for 5.5% of cancer-related deaths while only making up 3.1% of new cases, according to <a href="https://acsjournals.onlinelibrary.wiley.com/doi/10.3322/caac.21660">2020 GLOBOCAN</a> estimates. Its relative lethality is a result of multiple factors including its difficult diagnosis and rapid progression, resulting in only a <a href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)60643-6/fulltext">15–25% 5-year survival rate</a>. Determining the extent of tumor growth (or T-stage) is a critical part of accurate diagnosis and treatment, but this information can be challenging to obtain for esophageal cancer, particularly at early stages.</p> <h2 style="font-size: 100%"><strong>Computed tomography angiography</strong></h2> <p>Clinically, doctors utilize a number of complex methods for tumor-stage determination, including computed tomography angiography (CTA). This procedure combines a typical CT scan with the injection of a dyeing agent that provides blood vessel and tissue contrast. While the procedure can be highly accurate for late-stage esophageal tumors, <a href="https://academic.oup.com/dote/article/31/1/dox113/4101232">it struggles to accurately identify early tumors</a> while also being invasive and cost-prohibitive. This leaves room for improved methods that can more accurately categorize these tumors earlier, enabling improved treatment.</p> <p>The increased prevalence of powerful 3D reconstruction software has provided a new avenue for tumor analysis. These tools can perform a range of data post-processing and segmentation to not only identify tissue structures more accurately, but also to analyze the resulting reconstructions for trends and identifying characteristics.</p> <div id="attachment_1465" style="width: 2058px" class="wp-caption aligncenter"><img decoding="async" aria-describedby="caption-attachment-1465" class="size-full wp-image-1465" src="https://www.thermofisher.com/blog/atomic-resolution/wp-content/uploads/sites/22/2024/06/Tumor-Volume-Oesophageal-Cancer-Blog-Figure-1_2048x850.jpg" alt="Esophageal cancer tumor progression at different T-stages, reconstructed with Amira Software" title="Esophageal cancer tumor progression at different T-stages, reconstructed with Amira Software" width="2048" height="845" srcset="https://www.thermofisher.com/blog/atomic-resolution/wp-content/uploads/sites/22/2024/06/Tumor-Volume-Oesophageal-Cancer-Blog-Figure-1_2048x850.jpg 2048w, https://www.thermofisher.com/blog/atomic-resolution/wp-content/uploads/sites/22/2024/06/Tumor-Volume-Oesophageal-Cancer-Blog-Figure-1_2048x850-300x124.jpg 300w, https://www.thermofisher.com/blog/atomic-resolution/wp-content/uploads/sites/22/2024/06/Tumor-Volume-Oesophageal-Cancer-Blog-Figure-1_2048x850-1024x423.jpg 1024w, https://www.thermofisher.com/blog/atomic-resolution/wp-content/uploads/sites/22/2024/06/Tumor-Volume-Oesophageal-Cancer-Blog-Figure-1_2048x850-768x317.jpg 768w, https://www.thermofisher.com/blog/atomic-resolution/wp-content/uploads/sites/22/2024/06/Tumor-Volume-Oesophageal-Cancer-Blog-Figure-1_2048x850-1536x634.jpg 1536w" sizes="(max-width: 2048px) 100vw, 2048px" /><p id="caption-attachment-1465" class="wp-caption-text">Esophageal tumor progression at different T-stages, reconstructed with Amira Software. Figure reproduced in part from Wang et al. under CC BY 4.0.</p></div> <h2 style="font-size: 100%"><strong>Tumor volume correlates with esophageal cancer progression</strong></h2> <p>Researchers at the Army Medical University (Chongqing, China) and Shanxi Medical University have recently utilized Thermo Scientific™ Amira™ Software to <a href="https://onlinelibrary.wiley.com/doi/10.1002/cam4.6051">analyze a wide range of pre-operative CTA data</a> in order to find structural trends that could assist in the diagnosis of esophageal tumor growth. Data was collected from 155 patients with esophageal cancer at various T-stages, from T1 to T4. Utilizing the data segmentation and reconstruction capabilities of Amira Software, they were able to find strong correlation between tumor volume and T-stage. Additionally, the lengths of the major and minor axis of the tumor were also found to correlate with T-stage. Their results provide three critical properties that can be used to assist in the clinical determination of T-stage.</p> <div id="attachment_1466" style="width: 2058px" class="wp-caption aligncenter"><img decoding="async" aria-describedby="caption-attachment-1466" class="size-full wp-image-1466" src="https://www.thermofisher.com/blog/atomic-resolution/wp-content/uploads/sites/22/2024/06/Tumor-Volume-Oesophageal-Cancer-Blog-Figure-2_2048x1816.jpg" alt="Major and minor axes of esophageal cancer tumors at different T-stages, reconstructed with Amira Software." title="Major and minor axes of esophageal cancer tumors at different T-stages, reconstructed with Amira Software." width="2048" height="1816" srcset="https://www.thermofisher.com/blog/atomic-resolution/wp-content/uploads/sites/22/2024/06/Tumor-Volume-Oesophageal-Cancer-Blog-Figure-2_2048x1816.jpg 2048w, https://www.thermofisher.com/blog/atomic-resolution/wp-content/uploads/sites/22/2024/06/Tumor-Volume-Oesophageal-Cancer-Blog-Figure-2_2048x1816-300x266.jpg 300w, https://www.thermofisher.com/blog/atomic-resolution/wp-content/uploads/sites/22/2024/06/Tumor-Volume-Oesophageal-Cancer-Blog-Figure-2_2048x1816-1024x908.jpg 1024w, https://www.thermofisher.com/blog/atomic-resolution/wp-content/uploads/sites/22/2024/06/Tumor-Volume-Oesophageal-Cancer-Blog-Figure-2_2048x1816-768x681.jpg 768w, https://www.thermofisher.com/blog/atomic-resolution/wp-content/uploads/sites/22/2024/06/Tumor-Volume-Oesophageal-Cancer-Blog-Figure-2_2048x1816-1536x1362.jpg 1536w, https://www.thermofisher.com/blog/atomic-resolution/wp-content/uploads/sites/22/2024/06/Tumor-Volume-Oesophageal-Cancer-Blog-Figure-2_2048x1816-310x274.jpg 310w" sizes="(max-width: 2048px) 100vw, 2048px" /><p id="caption-attachment-1466" class="wp-caption-text">Major and minor axes of esophageal tumors at different T-stages, reconstructed with Amira Software. Figure reproduced in part from Wang et al. under CC BY 4.0.</p></div> <p>This study highlights the impact that advanced segmentation and 3D reconstruction can have on high-resolution imaging data. As we collect more and more information with advanced tools and techniques, it only becomes ever more important that we find ways to analyze and interpret that wealth of data. Versatile tools like Amira Software, with integrated automation and AI capabilities, allow you to extract critical details from your observations, leading to valuable insights that can shape clinical procedures and ultimately improve the lives of patients.</p> <p><a href="https://onlinelibrary.wiley.com/doi/10.1002/cam4.6051">Read the full article here >></a></p> <p><a href="https://www.thermofisher.com/us/en/home/electron-microscopy/products/software-em-3d-vis/amira-software/pre-clinical-research.html?cid=msd_vds_ls_anbio_amr_1486630_gl_oso_blg_74gyfn&utm_source=comms-blog&utm_medium=atomic%20resolution%20blog&utm_campaign=msd_vds_ls_anbio_amr_1486630_gl_oso_blg_74gyfn">Learn more about Amira Software and the benefits of 3D reconstruction for pre-clinical research >></a></p> <!--<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:trackback="http://madskills.com/public/xml/rss/module/trackback/"> <rdf:Description rdf:about="https://www.thermofisher.com/blog/atomic-resolution/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer/" dc:identifier="https://www.thermofisher.com/blog/atomic-resolution/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer/" dc:title="Tumor volume analysis with Amira Software assists in the diagnosis of esophageal cancer" trackback:ping="https://www.thermofisher.com/blog/atomic-resolution/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer/trackback/" /> </rdf:RDF>--> <div class="jp-relatedposts"> <div class="related-post related-1"> <a href="https://www.thermofisher.com/blog/atomic-resolution/what-is-cryo-em-what-is-cryo-electron-microscopy/"><img width="310" height="274" src="https://www.thermofisher.com/blog/atomic-resolution/wp-content/uploads/sites/22/2024/10/cryoEM-blog-virus-pore4-1920x600_Header-310x274.jpg" class="attachment-grid size-grid wp-post-image" alt="cryoEM-blog-virus pore" decoding="async" loading="lazy" /></a> <span class="grid-content"> <h4 class="entry-title"><a href="https://www.thermofisher.com/blog/atomic-resolution/what-is-cryo-em-what-is-cryo-electron-microscopy/">What is cryo-EM?</a></h4> <p>Cryo-EM: cryo electron microscopy Cryo-electron microscopy (... </p> <a href="https://www.thermofisher.com/blog/atomic-resolution/what-is-cryo-em-what-is-cryo-electron-microscopy/" class="read-more">Read More <i class="fa fa-icon fa-chevron-right"></i></a> </span> </div> <div class="related-post related-2"> <a href="https://www.thermofisher.com/blog/atomic-resolution/glacios-cryo-tem-evolution-200-kv-cryo-em/"><img width="310" height="274" src="https://www.thermofisher.com/blog/atomic-resolution/wp-content/uploads/sites/22/2023/02/Glacios2-CDK-cyclin-1200x630-1-310x274.png" class="attachment-grid size-grid wp-post-image" alt="Next gen Glacios Cryo TEM helps solve CDK-cyclin at 2.3 Angstroms" decoding="async" loading="lazy" /></a> <span class="grid-content"> <h4 class="entry-title"><a href="https://www.thermofisher.com/blog/atomic-resolution/glacios-cryo-tem-evolution-200-kv-cryo-em/">Glacios 2 Cryo-TEM and the Evolution of 200 kV Cryo-EM</a></h4> <p>Glacios 2 Cryo-TEM and the Evolution of 200 kV Cryo-EM Cryo-... </p> <a href="https://www.thermofisher.com/blog/atomic-resolution/glacios-cryo-tem-evolution-200-kv-cryo-em/" class="read-more">Read More <i class="fa fa-icon fa-chevron-right"></i></a> </span> </div> <div class="related-post related-3"> <a href="https://www.thermofisher.com/blog/atomic-resolution/revolutionizing-prostate-cancer-research-cryo-em-breakthroughs/"><img width="310" height="274" src="https://www.thermofisher.com/blog/atomic-resolution/wp-content/uploads/sites/22/2024/02/UTHSA-Bolg-Header_1920x800_DRAFT-310x274.jpg" class="attachment-grid size-grid wp-post-image" alt="Protein structure used in prostate cancer research determined with cryo EM" decoding="async" loading="lazy" /></a> <span class="grid-content"> <h4 class="entry-title"><a href="https://www.thermofisher.com/blog/atomic-resolution/revolutionizing-prostate-cancer-research-cryo-em-breakthroughs/">Revolutionizing Prostate Cancer Research: University of Texas Health Science Center’s Cryo-EM Breakthrough</a></h4> <p>Prostate cancer research at the University of Texas Health S... </p> <a href="https://www.thermofisher.com/blog/atomic-resolution/revolutionizing-prostate-cancer-research-cryo-em-breakthroughs/" class="read-more">Read More <i class="fa fa-icon fa-chevron-right"></i></a> </span> </div> <div class="related-post related-4"> <a href="https://www.thermofisher.com/blog/atomic-resolution/advanced-characterization-unravels-ebola-virus-structure-and-behavior/"><img width="310" height="274" src="https://www.thermofisher.com/blog/atomic-resolution/wp-content/uploads/sites/22/2024/01/Ebola-Blog-Header-Image_1920x800-310x274.jpg" class="attachment-grid size-grid wp-post-image" alt="" decoding="async" loading="lazy" /></a> <span class="grid-content"> <h4 class="entry-title"><a href="https://www.thermofisher.com/blog/atomic-resolution/advanced-characterization-unravels-ebola-virus-structure-and-behavior/">Advanced Characterization Unravels Ebola Virus Structure and Behavior</a></h4> <p>Mechanism of Ebola cell entry is critical for the developmen... </p> <a href="https://www.thermofisher.com/blog/atomic-resolution/advanced-characterization-unravels-ebola-virus-structure-and-behavior/" class="read-more">Read More <i class="fa fa-icon fa-chevron-right"></i></a> </span> </div> </div></div></article> <div id="respond" class="comment-respond"> <h3 id="reply-title" class="comment-reply-title">Leave a Reply <small><a rel="nofollow" id="cancel-comment-reply-link" href="/atomic-resolution/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer/#respond" style="display:none;">Cancel reply</a></small></h3><form action="https://www.thermofisher.com/blog/atomic-resolution/wp-comments-post.php" method="post" id="commentform" class="comment-form" novalidate><p class="comment-notes"><span id="email-notes">Your email address will not be published.</span> <span class="required-field-message">Required fields are marked <span class="required">*</span></span></p><p class="comment-form-comment"><label for="comment">Comment <span class="required">*</span></label> <textarea id="comment" name="comment" cols="45" rows="8" maxlength="65525" required></textarea></p><p class="comment-form-author"><label for="author">Name <span class="required">*</span></label> <input id="author" name="author" type="text" value="" size="30" maxlength="245" autocomplete="name" required /></p> <p class="comment-form-email"><label for="email">Email <span class="required">*</span></label> <input id="email" name="email" type="email" value="" size="30" maxlength="100" aria-describedby="email-notes" autocomplete="email" required /></p> <p class="comment-form-url"><label for="url">Website</label> <input id="url" name="url" type="url" value="" size="30" maxlength="200" autocomplete="url" /></p> <p class="comment-form-cookies-consent"><input id="wp-comment-cookies-consent" name="wp-comment-cookies-consent" type="checkbox" value="yes" /> <label for="wp-comment-cookies-consent">Save my name, email, and website in this browser for the next time I comment.</label></p> <p class="form-submit"><input name="submit" type="submit" id="submit" class="submit" value="Post Comment" /> <input type='hidden' name='comment_post_ID' value='1461' id='comment_post_ID' /> <input type='hidden' name='comment_parent' id='comment_parent' value='0' /> </p><p style="display: none;"><input type="hidden" id="akismet_comment_nonce" name="akismet_comment_nonce" value="3ecebcae4b" /></p><p style="display: none !important;" class="akismet-fields-container" data-prefix="ak_"><label>Δ<textarea name="ak_hp_textarea" cols="45" rows="8" maxlength="100"></textarea></label><input type="hidden" id="ak_js_1" name="ak_js" value="209"/><script>document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() );</script></p></form> </div><!-- #respond --> <div class="adjacent-entry-pagination pagination"><div class="pagination-previous alignleft"><i class="fa fa-icon fa-chevron-left"></i> <a href="https://www.thermofisher.com/blog/atomic-resolution/brain-evolution-through-the-study-of-teleost-fish-intelligence/" rel="prev">Unraveling Brain Evolution Through the Study of Teleost Fish Intelligence</a></div><div class="pagination-next alignright"><a href="https://www.thermofisher.com/blog/atomic-resolution/glacios-cryo-tem-evolution-200-kv-cryo-em/" rel="next">Glacios 2 Cryo-TEM and the Evolution of 200 kV Cryo-EM</a> <i class="fa fa-icon fa-chevron-right"></i></div></div></main></div></div><footer class="site-footer"><div class="wrap"><div class="creds"><p class="footer-links"><a href="https://corporate.thermofisher.com/en/footer/privacy-statement.html" target="_blank" rel="noopener noreferrer">Privacy Statement</a><a href="https://corporate.thermofisher.com/en/footer/terms-and-conditions.html" target="_blank" rel="noopener noreferrer">Terms & Conditions</a><a href="/blog/locations/">Locations</a><a href="/blog/sitemap/">Sitemap</a></p><p>© 2024 <a href="https://www.thermofisher.com">Thermo Fisher Scientific</a>. All Rights Reserved.</p></div><span class="social-links"><p>Talk to us</p><a href="https://www.facebook.com/thermofisher" class="facebook" target="_blank" rel="noopener noreferrer"><i class="fa fa-icon fa-facebook"></i></a><a href="https://www.linkedin.com/company/thermo-fisher-scientific" class="linkedin" target="_blank" rel="noopener noreferrer"><i class="fa fa-icon fa-linkedin"></i></a><a href="https://twitter.com/thermofisher" class="twitter" target="_blank" rel="noopener noreferrer"><i class="fa fa-icon fa-twitter"></i></a><a href="https://www.youtube.com/c/thermofisher" class="youtube" target="_blank" rel="noopener noreferrer"><i class="fa fa-icon fa-youtube"></i></a></span></div></footer></div> <!-- WP Live Search --> <script type="text/html" id="wpls--tmpl"> <li class="search-result"> <a href="<%= post.link %>"> <div class="wpls--item-title-wrap"> <h4 class="wpls--item-title"><%= post.title %></h4> </div> </a> </li> </script> <script type="text/javascript"> /* MonsterInsights Scroll Tracking */ if ( typeof(jQuery) !== 'undefined' ) { jQuery( document ).ready(function(){ function monsterinsights_scroll_tracking_load() { if ( ( typeof(__gaTracker) !== 'undefined' && __gaTracker && __gaTracker.hasOwnProperty( "loaded" ) && __gaTracker.loaded == true ) || ( typeof(__gtagTracker) !== 'undefined' && __gtagTracker ) ) { (function(factory) { factory(jQuery); }(function($) { /* Scroll Depth */ "use strict"; var defaults = { percentage: true }; var $window = $(window), cache = [], scrollEventBound = false, lastPixelDepth = 0; /* * Plugin */ $.scrollDepth = function(options) { var startTime = +new Date(); options = $.extend({}, defaults, options); /* * Functions */ function sendEvent(action, label, scrollDistance, timing) { if ( 'undefined' === typeof MonsterInsightsObject || 'undefined' === typeof MonsterInsightsObject.sendEvent ) { return; } var paramName = action.toLowerCase(); var fieldsArray = { send_to: 'G-TJ18KZWFVE', non_interaction: true }; fieldsArray[paramName] = label; if (arguments.length > 3) { fieldsArray.scroll_timing = timing MonsterInsightsObject.sendEvent('event', 'scroll_depth', fieldsArray); } else { MonsterInsightsObject.sendEvent('event', 'scroll_depth', fieldsArray); } } function calculateMarks(docHeight) { return { '25%' : parseInt(docHeight * 0.25, 10), '50%' : parseInt(docHeight * 0.50, 10), '75%' : parseInt(docHeight * 0.75, 10), /* Cushion to trigger 100% event in iOS */ '100%': docHeight - 5 }; } function checkMarks(marks, scrollDistance, timing) { /* Check each active mark */ $.each(marks, function(key, val) { if ( $.inArray(key, cache) === -1 && scrollDistance >= val ) { sendEvent('Percentage', key, scrollDistance, timing); cache.push(key); } }); } function rounded(scrollDistance) { /* Returns String */ return (Math.floor(scrollDistance/250) * 250).toString(); } function init() { bindScrollDepth(); } /* * Public Methods */ /* Reset Scroll Depth with the originally initialized options */ $.scrollDepth.reset = function() { cache = []; lastPixelDepth = 0; $window.off('scroll.scrollDepth'); bindScrollDepth(); }; /* Add DOM elements to be tracked */ $.scrollDepth.addElements = function(elems) { if (typeof elems == "undefined" || !$.isArray(elems)) { return; } $.merge(options.elements, elems); /* If scroll event has been unbound from window, rebind */ if (!scrollEventBound) { bindScrollDepth(); } }; /* Remove DOM elements currently tracked */ $.scrollDepth.removeElements = function(elems) { if (typeof elems == "undefined" || !$.isArray(elems)) { return; } $.each(elems, function(index, elem) { var inElementsArray = $.inArray(elem, options.elements); var inCacheArray = $.inArray(elem, cache); if (inElementsArray != -1) { options.elements.splice(inElementsArray, 1); } if (inCacheArray != -1) { cache.splice(inCacheArray, 1); } }); }; /* * Throttle function borrowed from: * Underscore.js 1.5.2 * http://underscorejs.org * (c) 2009-2013 Jeremy Ashkenas, DocumentCloud and Investigative Reporters & Editors * Underscore may be freely distributed under the MIT license. */ function throttle(func, wait) { var context, args, result; var timeout = null; var previous = 0; var later = function() { previous = new Date; timeout = null; result = func.apply(context, args); }; return function() { var now = new Date; if (!previous) previous = now; var remaining = wait - (now - previous); context = this; args = arguments; if (remaining <= 0) { clearTimeout(timeout); timeout = null; previous = now; result = func.apply(context, args); } else if (!timeout) { timeout = setTimeout(later, remaining); } return result; }; } /* * Scroll Event */ function bindScrollDepth() { scrollEventBound = true; $window.on('scroll.scrollDepth', throttle(function() { /* * We calculate document and window height on each scroll event to * account for dynamic DOM changes. */ var docHeight = $(document).height(), winHeight = window.innerHeight ? window.innerHeight : $window.height(), scrollDistance = $window.scrollTop() + winHeight, /* Recalculate percentage marks */ marks = calculateMarks(docHeight), /* Timing */ timing = +new Date - startTime; checkMarks(marks, scrollDistance, timing); }, 500)); } init(); }; /* UMD export */ return $.scrollDepth; })); jQuery.scrollDepth(); } else { setTimeout(monsterinsights_scroll_tracking_load, 200); } } monsterinsights_scroll_tracking_load(); }); } /* End MonsterInsights Scroll Tracking */ </script><script type="text/javascript" id="wpls-script-js-extra"> /* <![CDATA[ */ var wp_search_vars = {"helperText":"one more character","api":"https:\/\/admin.acceleratingscience.com\/wp-json\/as\/v1\/all-posts\/22"}; /* ]]> */ </script> <script type="text/javascript" src="https://www.thermofisher.com/blog/atomic-resolution/wp-content/plugins/wp-search-live/public/assets/js/wp-live-search.js?ver=0.9" id="wpls-script-js"></script> <script type="text/javascript" src="https://www.thermofisher.com/blog//wp-includes/js/comment-reply.min.js?ver=6.6.1" id="comment-reply-js" async="async" data-wp-strategy="async"></script> <script type="text/javascript" src="https://www.thermofisher.com/blog//wp-includes/js/dist/dom-ready.min.js?ver=f77871ff7694fffea381" id="wp-dom-ready-js"></script> <script type="text/javascript" src="https://www.thermofisher.com/blog//wp-includes/js/dist/hooks.min.js?ver=2810c76e705dd1a53b18" id="wp-hooks-js"></script> <script type="text/javascript" src="https://www.thermofisher.com/blog//wp-includes/js/dist/i18n.min.js?ver=5e580eb46a90c2b997e6" id="wp-i18n-js"></script> <script type="text/javascript" id="wp-i18n-js-after"> /* <![CDATA[ */ wp.i18n.setLocaleData( { 'text direction\u0004ltr': [ 'ltr' ] } ); /* ]]> */ </script> <script type="text/javascript" src="https://www.thermofisher.com/blog//wp-includes/js/dist/a11y.min.js?ver=d90eebea464f6c09bfd5" id="wp-a11y-js"></script> <script type="text/javascript" defer='defer' src="https://www.thermofisher.com/blog/atomic-resolution/wp-content/plugins/gravityforms/assets/js/dist/vendor-theme.min.js?ver=54e7080aa7a02c83aa61fae430b9d869" id="gform_gravityforms_theme_vendors-js"></script> <script type="text/javascript" id="gform_gravityforms_theme-js-extra"> /* <![CDATA[ */ var gform_theme_config = {"common":{"form":{"honeypot":{"version_hash":"4a792b070322e711c2521ee9802c04ea"}}},"hmr_dev":"","public_path":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/plugins\/gravityforms\/assets\/js\/dist\/"}; /* ]]> */ </script> <script type="text/javascript" defer='defer' src="https://www.thermofisher.com/blog/atomic-resolution/wp-content/plugins/gravityforms/assets/js/dist/scripts-theme.min.js?ver=bab19fd84843dabc070e73326d787910" id="gform_gravityforms_theme-js"></script> <script type="text/javascript" src="https://www.thermofisher.com/blog//wp-includes/js/jquery/ui/core.min.js?ver=1.13.3" id="jquery-ui-core-js"></script> <script type="text/javascript" src="https://www.thermofisher.com/blog//wp-includes/js/jquery/ui/tabs.min.js?ver=1.13.3" id="jquery-ui-tabs-js"></script> <script type="text/javascript" src="https://www.thermofisher.com/blog/atomic-resolution/wp-content/themes/accelerating-science-blogs/js/scripts.js?ver=1.2.9.3" id="scripts-js"></script> <script defer type="text/javascript" src="https://www.thermofisher.com/blog/atomic-resolution/wp-content/plugins/akismet/_inc/akismet-frontend.js?ver=1722950842" id="akismet-frontend-js"></script> <script type="text/javascript" src="/-JVF2Mt77XrPue0oWQ_DN-r_/XEYukNG8mrG8EimE/LFhk/MBsdTQN/rVQM"></script></body></html>