CINXE.COM

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</form> <form id="pathways_iga-producing_b_cells_in_the_intestine" action="/pathways/iga-producing-b-cells-in-the-intestine" method="post"> <li class=""> <a href="/pathways/iga-producing-b-cells-in-the-intestine" class="pathway_link" data-form="pathways_iga-producing_b_cells_in_the_intestine"> IgA-Producing B Cells in the Intestine </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-1_family_signaling_pathways" action="/pathways/il-1-family-signaling-pathways" method="post"> <li class=""> <a href="/pathways/il-1-family-signaling-pathways" class="pathway_link" data-form="pathways_il-1_family_signaling_pathways"> IL-1 Family Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-10_cytokine_family_signaling_pathway" action="/pathways/il-10-cytokine-family-signaling-pathway" method="post"> <li class=""> <a href="/pathways/il-10-cytokine-family-signaling-pathway" class="pathway_link" data-form="pathways_il-10_cytokine_family_signaling_pathway"> IL-10 Cytokine Family Signaling Pathway </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-11_signaling_pathways" action="/pathways/il-11-signaling-pathways" method="post"> <li class=""> <a href="/pathways/il-11-signaling-pathways" class="pathway_link" data-form="pathways_il-11_signaling_pathways"> IL-11 Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-12_family_signaling_pathways" action="/pathways/il-12-family-signaling-pathways" method="post"> <li class=""> <a href="/pathways/il-12-family-signaling-pathways" class="pathway_link" data-form="pathways_il-12_family_signaling_pathways"> IL-12 Family Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-15_signaling_pathways" action="/pathways/il15-signaling-pathways" method="post"> <li class=""> <a href="/pathways/il15-signaling-pathways" class="pathway_link" data-form="pathways_il-15_signaling_pathways"> IL-15 Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-15_signaling_pathways_and_their_primary_biological_effects_in_different_immune_cell_types" action="/pathways/il-15-signaling-pathways-their-primary-biological-effects-in-different-immune-cell-types" method="post"> <li class=""> <a href="/pathways/il-15-signaling-pathways-their-primary-biological-effects-in-different-immune-cell-types" class="pathway_link" data-form="pathways_il-15_signaling_pathways_and_their_primary_biological_effects_in_different_immune_cell_types"> IL-15 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-17_family_signaling_pathways" action="/pathways/il17-family-signaling-pathways" method="post"> <li class=""> <a href="/pathways/il17-family-signaling-pathways" class="pathway_link" data-form="pathways_il-17_family_signaling_pathways"> IL-17 Family Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-2_signaling_pathways" action="/pathways/il2-signaling-pathways" method="post"> <li class=""> <a href="/pathways/il2-signaling-pathways" class="pathway_link" data-form="pathways_il-2_signaling_pathways"> IL-2 Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-2_signaling_pathways_and_their_primary_biological_effects_in_different_immune_cell_types" action="/pathways/il-2-signaling-pathways-their-primary-biological-effects-in-different-immune-cell-types" method="post"> <li class=""> <a href="/pathways/il-2-signaling-pathways-their-primary-biological-effects-in-different-immune-cell-types" class="pathway_link" data-form="pathways_il-2_signaling_pathways_and_their_primary_biological_effects_in_different_immune_cell_types"> IL-2 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-21_signaling_pathways" action="/pathways/il21-signaling-pathways" method="post"> <li class=""> <a href="/pathways/il21-signaling-pathways" class="pathway_link" data-form="pathways_il-21_signaling_pathways"> IL-21 Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-21_signaling_pathways_and_their_primary_biological_effects_in_different_immune_cell_types" action="/pathways/il-21-signaling-pathways-their-primary-biological-effects-in-different-immune-cell-types" method="post"> <li class=""> <a href="/pathways/il-21-signaling-pathways-their-primary-biological-effects-in-different-immune-cell-types" class="pathway_link" data-form="pathways_il-21_signaling_pathways_and_their_primary_biological_effects_in_different_immune_cell_types"> IL-21 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-27_p28_il-30_signaling_pathways" action="/pathways/il-27-p28il-30-signaling-pathways" method="post"> <li class=""> <a href="/pathways/il-27-p28il-30-signaling-pathways" class="pathway_link" data-form="pathways_il-27_p28_il-30_signaling_pathways"> IL-27 p28/IL-30 Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-31_signaling_pathways" action="/pathways/il-31-signaling-pathways" method="post"> <li class=""> <a href="/pathways/il-31-signaling-pathways" class="pathway_link" data-form="pathways_il-31_signaling_pathways"> IL-31 Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-4_signaling_pathways" action="/pathways/il4-signaling-pathways" method="post"> <li class=""> <a href="/pathways/il4-signaling-pathways" class="pathway_link" data-form="pathways_il-4_signaling_pathways"> IL-4 Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-4_signaling_pathways_and_their_primary_biological_effects_in_different_immune_cell_types" action="/pathways/il-4-signaling-pathways-their-primary-biological-effects-in-different-immune-cell-types" method="post"> <li class=""> <a href="/pathways/il-4-signaling-pathways-their-primary-biological-effects-in-different-immune-cell-types" class="pathway_link" data-form="pathways_il-4_signaling_pathways_and_their_primary_biological_effects_in_different_immune_cell_types"> IL-4 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-6_signaling_pathways" action="/pathways/il-6-family-signaling-pathways" method="post"> <li class=""> <a href="/pathways/il-6-family-signaling-pathways" class="pathway_link" data-form="pathways_il-6_signaling_pathways"> IL-6 Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-7_signaling_pathways" action="/pathways/il7-signaling-pathways" method="post"> <li class=""> <a href="/pathways/il7-signaling-pathways" class="pathway_link" data-form="pathways_il-7_signaling_pathways"> IL-7 Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-7_signaling_pathways_and_their_primary_biological_effects_in_different_immune_cell_types" action="/pathways/il-7-signaling-pathways-their-primary-biological-effects-in-different-immune-cell-types" method="post"> <li class=""> <a href="/pathways/il-7-signaling-pathways-their-primary-biological-effects-in-different-immune-cell-types" class="pathway_link" data-form="pathways_il-7_signaling_pathways_and_their_primary_biological_effects_in_different_immune_cell_types"> IL-7 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-9_signaling_pathways" action="/pathways/il9-signaling-pathways" method="post"> <li class=""> <a href="/pathways/il9-signaling-pathways" class="pathway_link" data-form="pathways_il-9_signaling_pathways"> IL-9 Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-9_signaling_pathways_and_their_primary_biological_effects_in_different_immune_cell_types" action="/pathways/il-9-signaling-pathways-their-primary-biological-effects-in-different-immune-cell-types" method="post"> <li class=""> <a href="/pathways/il-9-signaling-pathways-their-primary-biological-effects-in-different-immune-cell-types" class="pathway_link" data-form="pathways_il-9_signaling_pathways_and_their_primary_biological_effects_in_different_immune_cell_types"> IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_inflammasome_activation_pathways" action="/pathways/inflammasome-activation-pathways" method="post"> <li class=""> <a href="/pathways/inflammasome-activation-pathways" class="pathway_link" data-form="pathways_inflammasome_activation_pathways"> Inflammasome Activation Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_innate_lymphoid_cell_differentiation_pathways" action="/pathways/innate-lymphoid-cell-differentiation-pathways" method="post"> <li class=""> <a href="/pathways/innate-lymphoid-cell-differentiation-pathways" class="pathway_link" data-form="pathways_innate_lymphoid_cell_differentiation_pathways"> Innate Lymphoid Cell Differentiation Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_lif_signaling_pathways" action="/pathways/lif-signaling-pathways" method="post"> <li class=""> <a href="/pathways/lif-signaling-pathways" class="pathway_link" data-form="pathways_lif_signaling_pathways"> LIF Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_mdsc-mediated_mechanisms_of_immunosuppression" action="/pathways/mdsc-mediated-mechanisms-of-immunosuppression" method="post"> <li class=""> <a href="/pathways/mdsc-mediated-mechanisms-of-immunosuppression" class="pathway_link" data-form="pathways_mdsc-mediated_mechanisms_of_immunosuppression"> MDSC-Mediated Mechanisms of Immunosuppression </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_mechanisms_of_regulatory_t_cell-mediated_suppression" action="/pathways/mechanisms-of-regulatory-t-cell-mediated-suppression" method="post"> <li class=""> <a href="/pathways/mechanisms-of-regulatory-t-cell-mediated-suppression" class="pathway_link" data-form="pathways_mechanisms_of_regulatory_t_cell-mediated_suppression"> Mechanisms of Regulatory T Cell-Mediated Suppression </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_mechanisms_of_tumor-associated_macrophage_tam-mediated_immunosuppression" action="/pathways/tumor-associated-macrophage-tam" method="post"> <li class=""> <a href="/pathways/tumor-associated-macrophage-tam" class="pathway_link" data-form="pathways_mechanisms_of_tumor-associated_macrophage_tam-mediated_immunosuppression"> Mechanisms of Tumor-Associated Macrophage TAM-Mediated Immunosuppression </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_mechanisms_of_tumor-derived_exosome_tex-mediated_immunosuppression" action="/pathways/mechanisms-tumor-derived-exosome-tex-mediated-immunosuppression" method="post"> <li class=""> <a href="/pathways/mechanisms-tumor-derived-exosome-tex-mediated-immunosuppression" class="pathway_link" data-form="pathways_mechanisms_of_tumor-derived_exosome_tex-mediated_immunosuppression"> Mechanisms of Tumor-derived Exosome TEX-mediated Immunosuppression </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_natural_killer_cell_receptors__human_target_cell_–_nk_cell_ligand-receptor_interactions" action="/pathways/natural-killer-cell-receptors-human-target-cell-nk-cell-ligand-receptor-interactions-pathway" method="post"> <li class=""> <a href="/pathways/natural-killer-cell-receptors-human-target-cell-nk-cell-ligand-receptor-interactions-pathway" class="pathway_link" data-form="pathways_natural_killer_cell_receptors__human_target_cell_–_nk_cell_ligand-receptor_interactions"> Natural Killer Cell Receptors: Human Target Cell – NK Cell Ligand-Receptor Interactions </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_neuropoietin_signaling_pathways" action="/pathways/neuropoietin-signaling-pathways" method="post"> <li class=""> <a href="/pathways/neuropoietin-signaling-pathways" class="pathway_link" data-form="pathways_neuropoietin_signaling_pathways"> Neuropoietin Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_nod-like_receptor_signaling_pathways" action="/pathways/nod-like-receptor-signaling-pathways" method="post"> <li class=""> <a href="/pathways/nod-like-receptor-signaling-pathways" class="pathway_link" data-form="pathways_nod-like_receptor_signaling_pathways"> NOD-like Receptor Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_oncostatin_m_signaling_pathways" action="/pathways/oncostatin-m-signaling-pathways" method="post"> <li class=""> <a href="/pathways/oncostatin-m-signaling-pathways" class="pathway_link" data-form="pathways_oncostatin_m_signaling_pathways"> Oncostatin M Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_pathogen_or_damage-activated_c-type_lectin_receptor_signaling_pathways" action="/pathways/pathogen-damage-activated-c-type-lectin-receptor-signaling-pathways" method="post"> <li class=""> <a href="/pathways/pathogen-damage-activated-c-type-lectin-receptor-signaling-pathways" class="pathway_link" data-form="pathways_pathogen_or_damage-activated_c-type_lectin_receptor_signaling_pathways"> Pathogen or Damage-activated C-Type Lectin Receptor Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_t_cell_co-signaling_pathway__ligand-receptor_interactions" action="/pathways/t-cell-co-signaling-pathway-lig-recept-interactions" method="post"> <li class=""> <a href="/pathways/t-cell-co-signaling-pathway-lig-recept-interactions" class="pathway_link" data-form="pathways_t_cell_co-signaling_pathway__ligand-receptor_interactions"> T Cell Co-Signaling Pathway: Ligand-Receptor Interactions </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_tgf-beta_signaling_pathways" action="/pathways/tgf-beta-signaling-pathways" method="post"> <li class=""> <a href="/pathways/tgf-beta-signaling-pathways" class="pathway_link" data-form="pathways_tgf-beta_signaling_pathways"> TGF-beta Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_th1_differentiation_pathway" action="/pathways/th1-differentiation-pathway" method="post"> <li class=""> <a href="/pathways/th1-differentiation-pathway" class="pathway_link" data-form="pathways_th1_differentiation_pathway"> Th1 Differentiation Pathway </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_th17_differentiation_pathway" action="/pathways/th17-differentiation-pathway" method="post"> <li class=""> <a href="/pathways/th17-differentiation-pathway" class="pathway_link" data-form="pathways_th17_differentiation_pathway"> Th17 Differentiation Pathway </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_th2_differentiation_pathway" action="/pathways/th2-differentiation-pathway" method="post"> <li class=""> <a href="/pathways/th2-differentiation-pathway" class="pathway_link" data-form="pathways_th2_differentiation_pathway"> Th2 Differentiation Pathway </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_tnf_superfamily_pathway__human_ligand-receptor_interactions__their_associated_functions" action="/pathways/tnf-superfamily-pathway-human-lig-recept-interactions-their-associated-functions" method="post"> <li class=""> <a href="/pathways/tnf-superfamily-pathway-human-lig-recept-interactions-their-associated-functions" class="pathway_link" data-form="pathways_tnf_superfamily_pathway__human_ligand-receptor_interactions__their_associated_functions"> TNF Superfamily Pathway: Human Ligand-Receptor Interactions & their Associated Functions </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_toll-like_receptor_signaling_pathways" action="/pathways/toll-like-receptor-signaling-pathways" method="post"> <li class=""> <a href="/pathways/toll-like-receptor-signaling-pathways" class="pathway_link" data-form="pathways_toll-like_receptor_signaling_pathways"> Toll-Like Receptor Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_type_i_interferon_signaling_pathways" action="/pathways/type-i-interferon-signaling-pathways" method="post"> <li class=""> <a href="/pathways/type-i-interferon-signaling-pathways" class="pathway_link" data-form="pathways_type_i_interferon_signaling_pathways"> Type I Interferon Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_type_ii_interferon_signaling_pathways" action="/pathways/type-ii-interferon-signaling-pathways" method="post"> <li class=""> <a href="/pathways/type-ii-interferon-signaling-pathways" class="pathway_link" data-form="pathways_type_ii_interferon_signaling_pathways"> Type II Interferon Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_type_iii_interferon_signaling_pathways" action="/pathways/type-iii-interferon-signaling-pathways" method="post"> <li class=""> <a href="/pathways/type-iii-interferon-signaling-pathways" class="pathway_link" data-form="pathways_type_iii_interferon_signaling_pathways"> Type III Interferon Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_vegf_-_vegf_r2_signaling_pathways" action="/pathways/vegf-vegf-r2-signaling-pathways" method="post"> <li class=""> <a href="/pathways/vegf-vegf-r2-signaling-pathways" class="pathway_link" data-form="pathways_vegf_-_vegf_r2_signaling_pathways"> VEGF - VEGF R2 Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_virus_detection_and_induction_of_antiviral_signaling_pathways_by_rig-i-like_receptors_rlr" action="/pathways/rig-i-like-receptor-signaling-pathways" method="post"> <li class=""> <a href="/pathways/rig-i-like-receptor-signaling-pathways" class="pathway_link" data-form="pathways_virus_detection_and_induction_of_antiviral_signaling_pathways_by_rig-i-like_receptors_rlr"> Virus Detection and Induction of Antiviral Signaling Pathways by RIG-I-like Receptors RLR </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> </ul> </li> <li class="pathways-li "> <form id="pathways_neuroscience_pathways" action="/pathways/neuroscience" method="post"> <a href="/pathways/neuroscience" data-form="pathways_neuroscience_pathways" class="pathway_link"> <span class="icon-"> Neuroscience Pathways </span> </a> <input type="hidden" name="pw_parent" value="Neuroscience"> </form> </li> <li class="pathways-li "> <form id="pathways_proteases__other_enzymes_pathways" action="/pathways/proteases" method="post"> <a href="/pathways/proteases" data-form="pathways_proteases__other_enzymes_pathways" class="pathway_link"> <span class="icon-"> Proteases & Other Enzymes Pathways </span> </a> <input type="hidden" name="pw_parent" value="proteases"> </form> </li> <li class="pathways-li "> <form id="pathways_signal_transduction_pathways" action="/pathways/signal-transduction" method="post"> <a href="/pathways/signal-transduction" data-form="pathways_signal_transduction_pathways" class="pathway_link"> <span class="icon-"> Signal Transduction Pathways </span> </a> <input type="hidden" name="pw_parent" value="signal-transduction"> </form> </li> <li class="pathways-li "> <form id="pathways_stem_cell_pathways" action="/pathways/stem-cells" method="post"> <a href="/pathways/stem-cells" data-form="pathways_stem_cell_pathways" class="pathway_link"> <span class="icon-"> Stem Cell Pathways </span> </a> <input type="hidden" name="pw_parent" value="stem-cells"> </form> </li> <li class="pathways-li "> <form id="pathways_ubiquitin_related_modifiers__pathways" action="/pathways/ubiquitin-related-modifiers-and-pathways" method="post"> <a href="/pathways/ubiquitin-related-modifiers-and-pathways" data-form="pathways_ubiquitin_related_modifiers__pathways" class="pathway_link"> <span class="icon-"> Ubiquitin, Related Modifiers, & Pathways </span> </a> <input type="hidden" name="pw_parent" value="ubiquitin-related-modifiers-and-pathways"> </form> </li> </ul> </div> </div> </div> </div> </div> <div class="pw_right col-xs-12 col-sm-8 col-md-9"> <div class="search_mobile_buttons"> <div class="pw_menu_toggle btn btn-tertiary">Show Categories</div> </div> <div class="pw_header"> <h1>Dendritic Cell Lineage Development Pathways</h1> <p id="pw-intro-txt">Click on the mouse or human dendritic cell progenitor cells at the top of the graphic or the different tissue-specific dendritic cell subsets at the bottom of the graphic to see a list of the cell surface and intracellular markers that have been used to identify each cell type.<br></p> <div id="pw-con" data-mapname="" data-primary_segment=""> <div id="pw-main-nav-wrapper"> <div class="row"> <div id="pw-button-nav-top" class="col-xs-12 col-sm-12"> <div class="row"> <div class="col-xs-12 col-sm-6 col-md-6" > <div id="pw-nav-subtitle"> Dendritic Cell Lineage Development Pathways </div> </div> <div id="pw-print-button-col" class="col-xs-12 col-sm-6 col-md-6" > <a href="#print-copy-form" id="btn-get-print-copy" class="btn btn-primary"><img class="btn-icon" src="https://resources.rndsystems.com/images/Pathways/icons/icon-image.svg"/> Get Print Copy</a> </div> </div> </div> </div> </div> <div id="pw-map"> <div id="pw-maps"> <div id="el1_gry" class="dc_development_all pw-label2 el-gray1 pw-gray" style="top:70px;left:240px;"> Mouse </div> <div id="el1_off" data-id="1" data-set="Mouse" data-type="" class="dc_development_all pw-label2 el-off1" style="top:70px;left:240px;"> Mouse</div> <div id="el1_ct" class="pw-tooltip" data-id="1"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el2_gry" class="dc_development_all pw-label2 el-gray2 pw-gray" style="top:125px;left:374px;"> Bone Marrow </div> <div id="el2_off" data-id="2" data-set="BoneMarrow" data-type="" class="dc_development_all pw-label2 el-off2" style="top:125px;left:374px;"> Bone 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href="/target/integrin-alpha-2b-cd41">Integrin alpha 2b/CD41-</a><br><a target="_blank" href="/target/sca-1-ly6">Sca-1/Ly6+</a><br><a target="_blank" href="/target/slam-cd150">SLAM/CD150+</a><br><a target="_blank" href="/target/2b4-cd244-slamf4">2B4/CD244/SLAMF4-</a><br> </div> </div> <div id="el4_gry" class="dc_development_all pw-label el-gray4 pw-gray" style="top:116px;left:182px;"> Hematopoietic Stem<br>Cell (HSC) </div> <div id="el4_off" data-id="4" data-set="HematopoieticStemCell-HSC-3" data-type="No Products Click" class="dc_development_all pw-label el-off4" style="top:116px;left:182px;"> Hematopoietic Stem<br>Cell (HSC)</div> <div id="el4_ct" class="pw-tooltip" data-id="4"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/search? common_name=CD34">CD34+</a><br><a target="_blank" href="/target/cd38">CD38-</a><br><a target="_blank" href="/target/cd48-slamf2">CD48/SLAMF2-</a><br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2-</a><br><a target="_blank" href="/target/integrin-alpha-2b-cd41">Integrin alpha 2b/CD41-</a><br><a target="_blank" href="/target/sca-1-ly6">Sca-1/Ly6+</a><br><a target="_blank" href="/target/slam-cd150">SLAM/CD150+</a><br><a target="_blank" href="/target/2b4-cd244-slamf4">2B4/CD244/SLAMF4-</a><br> </div> </div> <div id="el5_gry" class="dc_development_all pw-sprite el-gray5 pw-gray" style="top:158.66668701171875px;left:182.666748046875px;"> </div> <div id="el5_off" data-id="5" data-set="CommonMyeloidProgenitorCell-CMP4" data-type="No Products Click" class="dc_development_all pw-sprite el-off5" style="top:158.66668701171875px;left:182.666748046875px;"> </div> <div id="el5_ct" class="pw-tooltip" data-id="5"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/fc-gamma-riii-cd16">CD16/Fc gamma RIII<sup>low</sup></a><br><a target="_blank" href="/target/fc-gamma-rii-cd32">CD32/Fc gamma RII<sup>low</sup></a><br><a target="_blank" href="/target/cd34">CD34+</a><br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br><a target="_blank" href="/target/gm-csf-r-alpha">GM-CSF R+</a><br><a target="_blank" href="/target/il-3-r-alpha-cd123">IL-3 R alpha/CD123+</a><br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br><a target="_blank" href="/target/sca-1-ly6">Sca-1/Ly6-</a><br> </div> </div> <div id="el6_gry" class="dc_development_all pw-label pw-right el-gray6 pw-gray" style="top:159px;left:50px;"> Common Myeloid<br>Progenitor Cell (CMP) </div> <div id="el6_off" data-id="6" data-set="CommonMyeloidProgenitorCell-CMP4" data-type="No Products Click" class="dc_development_all pw-label pw-right el-off6" style="top:159px;left:50px;"> Common Myeloid<br>Progenitor Cell (CMP)</div> <div id="el6_ct" class="pw-tooltip" data-id="6"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/fc-gamma-riii-cd16">CD16/Fc gamma RIII<sup>low</sup></a><br><a target="_blank" href="/target/fc-gamma-rii-cd32">CD32/Fc gamma RII<sup>low</sup></a><br><a target="_blank" href="/target/cd34">CD34+</a><br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br><a target="_blank" href="/target/gm-csf-r-alpha">GM-CSF R+</a><br><a target="_blank" href="/target/il-3-r-alpha-cd123">IL-3 R alpha/CD123+</a><br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br><a target="_blank" href="/target/sca-1-ly6">Sca-1/Ly6-</a><br> </div> </div> <div id="el7_gry" class="dc_development_all pw-sprite el-gray7 pw-gray" style="top:210.66668701171875px;left:142.666748046875px;"> </div> <div id="el7_off" data-id="7" data-set="Granulocyte-MacrophageProgenitor-GMP-5" data-type="No Products Click" class="dc_development_all pw-sprite el-off7" style="top:210.66668701171875px;left:142.666748046875px;"> </div> <div id="el7_ct" class="pw-tooltip" data-id="7"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/fc-gamma-riii-cd16">CD16/Fc gamma RIII<sup>high</sup></a><br><a target="_blank" href="/target/fc-gamma-rii-cd32">CD32/Fc gamma RII<sup>high</sup></a><br><a target="_blank" href="/target/cd34">CD34+</a><br><a target="_blank" href="/target/cd38">CD38+</a><br>CD45RA+<br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br><a target="_blank" href="/target/gm-csf-r-alpha">GM-CSF R+</a><br><a target="_blank" href="/target/il-3-r-alpha-cd123">IL-3 R alpha/CD123+</a><br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br><a target="_blank" href="/target/sca-1-ly6">Sca-1/Ly6-</a><br> </div> </div> <div id="el8_gry" class="dc_development_all pw-label el-gray8 pw-gray" style="top:215px;left:182px;"> Granulocyte-Macrophage<br>Progenitor (GMP) </div> <div id="el8_off" data-id="8" data-set="Granulocyte-MacrophageProgenitor-GMP-5" data-type="No Products Click" class="dc_development_all pw-label el-off8" style="top:215px;left:182px;"> Granulocyte-Macrophage<br>Progenitor (GMP)</div> <div id="el8_ct" class="pw-tooltip" data-id="8"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/fc-gamma-riii-cd16">CD16/Fc gamma RIII<sup>high</sup></a><br><a target="_blank" href="/target/fc-gamma-rii-cd32">CD32/Fc gamma RII<sup>high</sup></a><br><a target="_blank" href="/target/cd34">CD34+</a><br><a target="_blank" href="/target/cd38">CD38+</a><br>CD45RA+<br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br><a target="_blank" href="/target/gm-csf-r-alpha">GM-CSF R+</a><br><a target="_blank" href="/target/il-3-r-alpha-cd123">IL-3 R alpha/CD123+</a><br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br><a target="_blank" href="/target/sca-1-ly6">Sca-1/Ly6-</a><br> </div> </div> <div id="el9_gry" class="dc_development_all pw-sprite el-gray9 pw-gray" style="top:268.66668701171875px;left:170.666748046875px;"> </div> <div id="el9_off" data-id="9" data-set="Macrophage-DendriticProgenitor-MDP-6" data-type="No Products Click" class="dc_development_all pw-sprite el-off9" style="top:268.66668701171875px;left:170.666748046875px;"> </div> <div id="el9_ct" class="pw-tooltip" data-id="9"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M-</a><br><a target="_blank" href="/target/fc-gamma-riii-cd16">CD16/Fc gamma RIII<sup>high</sup></a><br><a target="_blank" href="/target/fc-gamma-rii-cd32">CD32/Fc gamma RII<sup>high</sup></a><br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit+</a><br><a target="_blank" href="/target/il-7-r-alpha-cd127">CD127/IL-7 R alpha-</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br><a target="_blank" href="/target/gm-csf-r-alpha">GM-CSF R+</a><br>Ly-6C-<br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br><a target="_blank" href="/target/sca-1-ly6">Sca-1/Ly6-</a><br> </div> </div> <div id="el10_gry" class="dc_development_all pw-label pw-right el-gray10 pw-gray" style="top:274px;left:34px;"> Macrophage-Dendritic<br>Progenitor (MDP) </div> <div id="el10_off" data-id="10" data-set="Macrophage-DendriticProgenitor-MDP-6" data-type="No Products Click" class="dc_development_all pw-label pw-right el-off10" style="top:274px;left:34px;"> Macrophage-Dendritic<br>Progenitor (MDP)</div> <div id="el10_ct" class="pw-tooltip" data-id="10"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M-</a><br><a target="_blank" href="/target/fc-gamma-riii-cd16">CD16/Fc gamma RIII<sup>high</sup></a><br><a target="_blank" href="/target/fc-gamma-rii-cd32">CD32/Fc gamma RII<sup>high</sup></a><br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit+</a><br><a target="_blank" href="/target/il-7-r-alpha-cd127">CD127/IL-7 R alpha-</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br><a target="_blank" href="/target/gm-csf-r-alpha">GM-CSF R+</a><br>Ly-6C-<br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br><a target="_blank" href="/target/sca-1-ly6">Sca-1/Ly6-</a><br> </div> </div> <div id="el11_gry" class="dc_development_all pw-sprite el-gray11 pw-gray" style="top:358.66668701171875px;left:180.666748046875px;"> </div> <div id="el11_off" data-id="11" data-set="CommonDendriticProgenitor-CDP-7" data-type="No Products Click" class="dc_development_all pw-sprite el-off11" style="top:358.66668701171875px;left:180.666748046875px;"> </div> <div id="el11_ct" class="pw-tooltip" data-id="11"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M-</a><br><a target="_blank" href="/target/fc-gamma-riii-cd16">CD16/Fc gamma RIII<sup>low</sup></a><br><a target="_blank" href="/target/fc-gamma-rii-cd32">CD32/Fc gamma RII<sup>low</sup></a><br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit<sup>int</sup></a><br><a target="_blank" href="/target/il-7-r-alpha-cd127">CD127/IL-7 R alpha-</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br><a target="_blank" href="/target/gm-csf-r-alpha">GM-CSF R+</a><br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br><a target="_blank" href="/target/sca-1-ly6">Sca-1/Ly6-</a><br> </div> </div> <div id="el12_gry" class="dc_development_all pw-label pw-right el-gray12 pw-gray" style="top:357px;left:65px;"> Common Dendritic<br>Progenitor (CDP) </div> <div id="el12_off" data-id="12" data-set="CommonDendriticProgenitor-CDP-7" data-type="No Products Click" class="dc_development_all pw-label pw-right el-off12" style="top:357px;left:65px;"> Common Dendritic<br>Progenitor (CDP)</div> <div id="el12_ct" class="pw-tooltip" data-id="12"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M-</a><br><a target="_blank" href="/target/fc-gamma-riii-cd16">CD16/Fc gamma RIII<sup>low</sup></a><br><a target="_blank" href="/target/fc-gamma-rii-cd32">CD32/Fc gamma RII<sup>low</sup></a><br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit<sup>int</sup></a><br><a target="_blank" href="/target/il-7-r-alpha-cd127">CD127/IL-7 R alpha-</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br><a target="_blank" href="/target/gm-csf-r-alpha">GM-CSF R+</a><br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br><a target="_blank" href="/target/sca-1-ly6">Sca-1/Ly6-</a><br> </div> </div> <div id="el13_gry" class="dc_development_all pw-sprite el-gray13 pw-gray" style="top:318.66668701171875px;left:250.666748046875px;"> </div> <div id="el13_off" data-id="13" data-set="CommonMonocyteProgenitor-cMoP-8" data-type="No Products Click" class="dc_development_all pw-sprite el-off13" style="top:318.66668701171875px;left:250.666748046875px;"> </div> <div id="el13_ct" class="pw-tooltip" data-id="13"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M-</a><br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2-</a><br>Ly-6C+<br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br> </div> </div> <div id="el14_gry" class="dc_development_all pw-label el-gray14 pw-gray" style="top:290.66668701171875px;left:248px;"> Common Monocyte<br>Progenitor (cMoP) </div> <div id="el14_off" data-id="14" data-set="CommonMonocyteProgenitor-cMoP-8" data-type="No Products Click" class="dc_development_all pw-label el-off14" style="top:290.66668701171875px;left:248px;"> Common Monocyte<br>Progenitor (cMoP)</div> <div id="el14_ct" class="pw-tooltip" data-id="14"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M-</a><br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2-</a><br>Ly-6C+<br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br> </div> </div> <div id="el15_gry" class="dc_development_all pw-sprite el-gray15 pw-gray" style="top:490.66668701171875px;left:218.666748046875px;"> </div> <div id="el15_off" data-id="15" data-set="Pre-DC9" data-type="No Products Click" class="dc_development_all pw-sprite el-off15" style="top:490.66668701171875px;left:218.666748046875px;"> </div> <div id="el15_ct" class="pw-tooltip" data-id="15"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd4">CD4-</a><br><a target="_blank" href="/target/cd8">CD8-</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+</a><br><a target="_blank" href="/target/cd11c">CD11c<sup>int</sup></a><br><a target="_blank" href="/target/fc-gamma-riii-cd16">CD16/Fc gamma RIII-</a><br><a target="_blank" href="/target/fc-gamma-rii-cd32">CD32/Fc gamma RII-</a><br><a target="_blank" href="/target/cd43">CD43<sup>int</sup></a><br>CD45RA<sup>low</sup><br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit-</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br><a target="_blank" href="/target/gm-csf-r-alpha">GM-CSF R+</a><br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II-</a><br> </div> </div> <div id="el16_gry" class="dc_development_all pw-label el-gray16 pw-gray" style="top:478.66668701171875px;left:234px;"> Pre-DC </div> <div id="el16_off" data-id="16" data-set="Pre-DC9" data-type="No Products Click" class="dc_development_all pw-label el-off16" style="top:478.66668701171875px;left:234px;"> Pre-DC</div> <div id="el16_ct" class="pw-tooltip" data-id="16"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd4">CD4-</a><br> <a target="_blank" href="/target/cd8">CD8-</a><br> <a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+</a><br> <a target="_blank" href="/target/cd11c">CD11c<sup>int</sup></a><br> <a target="_blank" href="/target/fc-gamma-riii-cd16">CD16/Fc gamma RIII-</a><br> <a target="_blank" href="/target/fc-gamma-rii-cd32">CD32/Fc gamma RII-</a><br> <a target="_blank" href="/target/cd43">CD43<sup>int</sup></a><br> CD45RA<sup>low</sup><br> <a target="_blank" href="/target/cd117-c-kit">CD117/c-kit-</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1+</a><br> <a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br> <a target="_blank" href="/target/gm-csf-r-alpha">GM-CSF R+</a><br> <a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br> <a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II-</a><br> </div> </div> <div id="el17_gry" class="dc_development_all pw-sprite el-gray17 pw-gray" style="top:434.66668701171875px;left:262.666748046875px;"> </div> <div id="el17_off" data-id="17" data-set="PlasmacytoidDendriticCell-pDC-10" data-type="No Products Click" class="dc_development_all pw-sprite el-off17" style="top:434.66668701171875px;left:262.666748046875px;"> </div> <div id="el17_ct" class="pw-tooltip" data-id="17"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br><a target="_blank" href="/target/b220-cd45r">B220/CD45 R+</a><br><a target="_blank" href="/target/bst-2-tetherin">Bst-2/PDCA-1+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M-</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/clec9a">CLEC9a+</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br>Ly-6C+<br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/siglec-h">Siglec-H+</a><br><strong>Intracellular Markers</strong><br>E2-2/Tcf4+</a><br>IRF7+<br><a target="_blank" href="/target/irf8">IRF8+</a><br><a target="_blank" href="/target/spi-b">Spi-B+</a><br><a target="_blank" href="/target/tlr7">TLR7+</a><br><a target="_blank" href="/target/tlr9">TLR9+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/ifn-alpha">IFN-alpha</a><br><a target="_blank" href="/target/ifn-beta">IFN-beta</a><br><a target="_blank" href="/target/il-6">IL-6</a><br><a target="_blank" href="/target/tnf-alpha">TNF-alpha</a><br> </div> </div> <div id="el18_gry" class="dc_development_all pw-label pw-center el-gray18 pw-gray" style="top:410px;left:215px;"> Plasmacytoid<br>Dendritic Cell (pDC) </div> <div id="el18_off" data-id="18" data-set="PlasmacytoidDendriticCell-pDC-10" data-type="No Products Click" class="dc_development_all pw-label pw-center el-off18" style="top:410px;left:215px;"> Plasmacytoid<br>Dendritic Cell (pDC)</div> <div id="el18_ct" class="pw-tooltip" data-id="18"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong> <br><a target="_blank" href="/target/b220-cd45r">B220/CD45 R+</a><br><a target="_blank" href="/target/bst-2-tetherin">Bst-2/PDCA-1+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M-</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/clec9a">CLEC9a+</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br>Ly-6C+<br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/siglec-h">Siglec-H+</a><br><strong>Intracellular Markers</strong><br>E2-2/Tcf4+<br>IRF7+<br><a target="_blank" href="/target/irf8">IRF8+</a><br><a target="_blank" href="/target/spi-b">Spi-B</a><br><a target="_blank" href="/target/tlr7">TLR7+</a><br><a target="_blank" href="/target/tlr9">TLR9+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/ifn-alpha">IFN-alpha</a><br><a target="_blank" href="/target/ifn-beta">IFN-beta</a><br><a target="_blank" href="/target/il-6">IL-6</a><br><a target="_blank" href="/target/tnf-alpha">TNF-alpha</a><br> </div> </div> <div id="el19_gry" class="dc_development_all pw-sprite el-gray19 pw-gray" style="top:378.66668701171875px;left:306.666748046875px;"> </div> <div id="el19_off" data-id="19" data-set="Monocyte11" data-type="No Products Click" class="dc_development_all pw-sprite el-off19" style="top:378.66668701171875px;left:306.666748046875px;"> </div> <div id="el19_ct" class="pw-tooltip" data-id="19"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/ccr2">CCR2-/+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+</a><br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit-</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1-/+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2-</a><br>Ly-6C<sup>high</sup> or Ly-6C<sup>low</sup></a><br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br> </div> </div> <div id="el20_gry" class="dc_development_all pw-label el-gray20 pw-gray" style="top:366.66668701171875px;left:318px;"> Monocyte </div> <div id="el20_off" data-id="20" data-set="Monocyte11" data-type="No Products Click" class="dc_development_all pw-label el-off20" style="top:366.66668701171875px;left:318px;"> Monocyte</div> <div id="el20_ct" class="pw-tooltip" data-id="20"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/ccr2">CCR2-/+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+</a><br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit-</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1-/+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2-</a><br>Ly-6C<sup>high</sup> or Ly-6C<sup>low</sup></a><br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br> </div> </div> <div id="el21_gry" class="dc_development_all pw-label2 el-gray21 pw-gray" style="top:416px;left:7px;"> Yolk sac-derived<br>Erythromeyloid<br>Progenitor Cell </div> <div id="el21_off" data-id="21" data-set="Yolksac-derivedErythromeyloidProgenitorCell" data-type="" class="dc_development_all pw-label2 el-off21" style="top:416px;left:7px;"> Yolk sac-derived<br>Erythromeyloid<br>Progenitor Cell</div> <div id="el21_ct" class="pw-tooltip" data-id="21"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el22_gry" class="dc_development_all pw-label2 el-gray22 pw-gray" style="top:478.66668701171875px;left:10px;"> P-Sp or AGM<br>HSC Progenitor </div> <div id="el22_off" data-id="22" data-set="P-SporAGMHSCProgenitor" data-type="" class="dc_development_all pw-label2 el-off22" style="top:478.66668701171875px;left:10px;"> P-Sp or AGM<br>HSC Progenitor</div> <div id="el22_ct" class="pw-tooltip" data-id="22"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el23_gry" class="dc_development_all pw-label2 el-gray23 pw-gray" style="top:558.6666870117188px;left:52px;"> HSC </div> <div id="el23_off" data-id="23" data-set="HSC" data-type="" class="dc_development_all pw-label2 el-off23" style="top:558.6666870117188px;left:52px;"> HSC</div> <div id="el23_ct" class="pw-tooltip" data-id="23"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el24_gry" class="dc_development_all pw-label2 el-gray24 pw-gray" style="top:486.66668701171875px;left:144px;"> Myeloid<br>Progenitor<br>Cell </div> <div id="el24_off" data-id="24" data-set="MyeloidProgenitorCell" data-type="" class="dc_development_all pw-label2 el-off24" style="top:486.66668701171875px;left:144px;"> Myeloid<br>Progenitor<br>Cell</div> <div id="el24_ct" class="pw-tooltip" data-id="24"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el25_gry" class="dc_development_all pw-label2 el-gray25 pw-gray" style="top:546.6666870117188px;left:140px;"> cMoP </div> <div id="el25_off" data-id="25" data-set="cMoP" data-type="" class="dc_development_all pw-label2 el-off25" style="top:546.6666870117188px;left:140px;"> cMoP</div> <div id="el25_ct" class="pw-tooltip" data-id="25"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el26_gry" class="dc_development_all pw-label2 el-gray26 pw-gray" style="top:638px;left:15px;"> Fetal Liver </div> <div id="el26_off" data-id="26" data-set="FetalLiver" data-type="" class="dc_development_all pw-label2 el-off26" style="top:638px;left:15px;"> Fetal Liver</div> <div id="el26_ct" class="pw-tooltip" data-id="26"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el27_gry" class="dc_development_all pw-label2 el-gray27 pw-gray" style="top:714px;left:12px;"> Yolk sac-derived<br>Erythromyeloid<br>Progenitor Cell </div> <div id="el27_off" data-id="27" data-set="Yolksac-derivedErythromyeloidProgenitorCell" data-type="" class="dc_development_all pw-label2 el-off27" style="top:714px;left:12px;"> Yolk sac-derived<br>Erythromyeloid<br>Progenitor Cell</div> <div id="el27_ct" class="pw-tooltip" data-id="27"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el28_gry" class="dc_development_all pw-label2 pw-center el-gray28 pw-gray" style="top:690px;left:108px;"> Fetal Liver-derived<br>Monocyte </div> <div id="el28_off" data-id="28" data-set="FetalLiver-derivedMonocyte" data-type="" class="dc_development_all pw-label2 pw-center el-off28" style="top:690px;left:108px;"> Fetal Liver-derived<br>Monocyte</div> <div id="el28_ct" class="pw-tooltip" data-id="28"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el29_gry" class="dc_development_all pw-sprite el-gray29 pw-gray" style="top:626.666748046875px;left:192.666748046875px;"> </div> <div id="el29_off" data-id="29" data-set="Pre-DC20" data-type="" class="dc_development_all pw-sprite el-off29" style="top:626.666748046875px;left:192.666748046875px;"> </div> <div id="el29_ct" class="pw-tooltip" data-id="29"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd4">CD4-</a><br><a target="_blank" href="/target/cd8">CD8-</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+</a><br><a target="_blank" href="/target/cd11c">CD11c<sup>int</sup></a><br><a target="_blank" href="/target/fc-gamma-riii-cd16">CD16/Fc gamma RIII-</a><br><a target="_blank" href="/target/fc-gamma-rii-cd32">CD32/Fc gamma RII-</a><br><a target="_blank" href="/target/cd43">CD43<sup>int</sup></a><br>CD45RA<sup>low</sup><br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit-</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br><a target="_blank" href="/target/gm-csf-r-alpha">GM-CSF R+</a><br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II-</a><br> </div> </div> <div id="el30_gry" class="dc_development_all pw-label el-gray30 pw-gray" style="top:638.666748046875px;left:232px;"> Pre-DC </div> <div id="el30_off" data-id="30" data-set="Pre-DC20" data-type="No Products Click" class="dc_development_all pw-label el-off30" style="top:638.666748046875px;left:232px;"> Pre-DC</div> <div id="el30_ct" class="pw-tooltip" data-id="30"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd4">CD4-</a><br><a target="_blank" href="/target/cd8">CD8-</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+</a><br><a target="_blank" href="/target/cd11c">CD11c<sup>int</sup></a><br><a target="_blank" href="/target/fc-gamma-riii-cd16">CD16/Fc gamma RIII-</a><br><a target="_blank" href="/target/fc-gamma-rii-cd32">CD32/Fc gamma RII-</a><br><a target="_blank" href="/target/cd43">CD43<sup>int</sup></a><br>CD45RA<sup>low</sup><br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit-</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br><a target="_blank" href="/target/gm-csf-r-alpha">GM-CSF R+</a><br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II-</a><br> </div> </div> <div id="el31_gry" class="dc_development_all pw-sprite el-gray31 pw-gray" style="top:568.6666870117188px;left:266.666748046875px;"> </div> <div id="el31_off" data-id="31" data-set="pDC21" data-type="No Products Click" class="dc_development_all pw-sprite el-off31" style="top:568.6666870117188px;left:266.666748046875px;"> </div> <div id="el31_ct" class="pw-tooltip" data-id="31"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br><a target="_blank" href="/target/b220-cd45r">B220/CD45 R+</a><br><a target="_blank" href="/target/bst-2-tetherin">Bst-2/PDCA-1+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M-</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/clec9a">CLEC9a+</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br>Ly-6C+<br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/siglec-h">Siglec-H+</a><br><strong>Intracellular Markers</strong><br>E2-2/Tcf4+<br>IRF7+<br><a target="_blank" href="/target/irf8">IRF8+</a><br><a target="_blank" href="/target/spi-b">Spi-B+</a><br><a target="_blank" href="/target/tlr7">TLR7+</a><br><a target="_blank" href="/target/tlr9">TLR9+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/ifn-alpha">IFN-alpha</a><br><a target="_blank" href="/target/ifn-beta">IFN-beta</a><br><a target="_blank" href="/target/il-6">IL-6</a><br><a target="_blank" href="/target/tnf-alpha">TNF-alpha</a><br> </div> </div> <div id="el32_gry" class="dc_development_all pw-label el-gray32 pw-gray" style="top:596.6666870117188px;left:280px;"> pDC </div> <div id="el32_off" data-id="32" data-set="pDC21" data-type="No Products Click" class="dc_development_all pw-label el-off32" style="top:596.6666870117188px;left:280px;"> pDC</div> <div id="el32_ct" class="pw-tooltip" data-id="32"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br><a target="_blank" href="/target/b220-cd45r">B220/CD45 R+</a><br><a target="_blank" href="/target/bst-2-tetherin">Bst-2/PDCA-1+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M-</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/clec9a">CLEC9a+</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br>Ly-6C+<br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/siglec-h">Siglec-H+</a><br><strong>Intracellular Markers</strong><br>E2-2/Tcf4+<br>IRF7+<br><a target="_blank" href="/target/irf8">IRF8+</a><br><a target="_blank" href="/target/spi-b">Spi-B+</a><br><a target="_blank" href="/target/tlr7">TLR7+</a><br><a target="_blank" href="/target/tlr9">TLR9+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/ifn-alpha">IFN-alpha</a><br><a target="_blank" href="/target/ifn-beta">IFN-beta</a><br><a target="_blank" href="/target/il-6">IL-6</a><br><a target="_blank" href="/target/tnf-alpha">TNF-alpha</a><br> </div> </div> <div id="el33_gry" class="dc_development_all pw-sprite el-gray33 pw-gray" style="top:516.6666870117188px;left:332.666748046875px;"> </div> <div id="el33_off" data-id="33" data-set="BloodMonocyte22" data-type="No Products Click" class="dc_development_all pw-sprite el-off33" style="top:516.6666870117188px;left:332.666748046875px;"> </div> <div id="el33_ct" class="pw-tooltip" data-id="33"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/ccr2">CCR2-/+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+</a><br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit-</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1-/+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2-</a><br>Ly-6C<sup>high</sup> or Ly-6C<sup>low</sup></a><br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br> </div> </div> <div id="el34_gry" class="dc_development_all pw-label pw-center el-gray34 pw-gray" style="top:550px;left:319px;"> Blood<br>Monocyte </div> <div id="el34_off" data-id="34" data-set="BloodMonocyte22" data-type="No Products Click" class="dc_development_all pw-label pw-center el-off34" style="top:550px;left:319px;"> Blood<br>Monocyte</div> <div id="el34_ct" class="pw-tooltip" data-id="34"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/ccr2">CCR2-/+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+</a><br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit-</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1-/+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2-</a><br>Ly-6C<sup>high</sup> or Ly-6C<sup>low</sup></a><br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br> </div> </div> <div id="el35_gry" class="dc_development_all pw-label2 el-gray35 pw-gray" style="top:789px;left:94px;"> Mouse Skin </div> <div id="el35_off" data-id="35" data-set="MouseSkin" data-type="" class="dc_development_all pw-label2 el-off35" style="top:789px;left:94px;"> Mouse Skin</div> <div id="el35_ct" class="pw-tooltip" data-id="35"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el36_gry" class="dc_development_all pw-sprite el-gray36 pw-gray" style="top:820.6666870117188px;left:52.666748046875px;"> </div> <div id="el36_off" data-id="36" data-set="LangerhansCell24" data-type="" class="dc_development_all pw-sprite el-off36" style="top:820.6666870117188px;left:52.666748046875px;"> </div> <div id="el36_ct" class="pw-tooltip" data-id="36"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd24">CD24+</a><br><a target="_blank" href="/target/integrin-alpha-e-cd103">CD103/Integrin alpha E-</a><br><a target="_blank" href="/target/clec9a">CLEC9a-</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209+</a><br><a target="_blank" href="/target/dec-205-cd205">DEC-205/CD205+</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1+</a><br><a target="_blank" href="/target/f4-80">F4/80+</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207+</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a+</a><br> </div> </div> <div id="el37_gry" class="dc_development_all pw-label pw-center el-gray37 pw-gray" style="top:860.6666870117188px;left:30px;"> Langerhans<br>Cell </div> <div id="el37_off" data-id="37" data-set="LangerhansCell24" data-type="No Products Click" class="dc_development_all pw-label pw-center el-off37" style="top:860.6666870117188px;left:30px;"> Langerhans<br>Cell</div> <div id="el37_ct" class="pw-tooltip" data-id="37"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd24">CD24+</a><br><a target="_blank" href="/target/integrin-alpha-e-cd103">CD103/Integrin alpha E-</a><br><a target="_blank" href="/target/clec9a">CLEC9a-</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209+</a><br><a target="_blank" href="/target/dec-205-cd205">DEC-205/CD205+</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1+</a><br><a target="_blank" href="/target/f4-80">F4/80+</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207+</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a+</a><br> </div> </div> <div id="el38_gry" class="dc_development_all pw-sprite el-gray38 pw-gray" style="top:820.6666870117188px;left:130.666748046875px;"> </div> <div id="el38_off" data-id="38" data-set="CD103-CD11b-CD207-DermalDC25" data-type="No Products Click" class="dc_development_all pw-sprite el-off38" style="top:820.6666870117188px;left:130.666748046875px;"> </div> <div id="el38_ct" class="pw-tooltip" data-id="38"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cd4">CD4-</a><br><a target="_blank" href="/target/cd8">CD8 alpha-</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M<sup>-/low</sup></a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd24">CD24+</a><br><a target="_blank" href="/target/integrin-alpha-e-cd103">CD103/Integrin alpha E+</a><br><a target="_blank" href="/target/clec9a">CLEC9a+</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1-</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209-</a><br><a target="_blank" href="/target/dec-205-cd205">DEC-205/CD205+</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1<sup>-/low</sup></a><br><a target="_blank" href="/target/f4-80">F4/80-</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207+</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a-</a><br><a target="_blank" href="/target/xcr1">XCR1+</a><br> </div> </div> <div id="el39_gry" class="dc_development_all pw-label pw-center el-gray39 pw-gray" style="top:864px;left:99px;"> CD103<sup>+</sup> CD11b<sup>-</sup><br>CD207<sup>+</sup> Dermal DC </div> <div id="el39_off" data-id="39" data-set="CD103-CD11b-CD207-DermalDC25" data-type="No Products Click" class="dc_development_all pw-label pw-center el-off39" style="top:864px;left:99px;"> CD103<sup>+</sup> CD11b<sup>-</sup><br>CD207<sup>+</sup> Dermal DC</div> <div id="el39_ct" class="pw-tooltip" data-id="39"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cd4">CD4-</a><br><a target="_blank" href="/target/cd8">CD8 alpha-</a><br> <a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M<sup>-/low</sup></a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd24">CD24+</a><br><a target="_blank" href="/target/integrin-alpha-e-cd103">CD103/Integrin alpha E+</a><br><a target="_blank" href="/target/clec9a">CLEC9a+</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1-</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209-</a><br><a target="_blank" href="/target/dec-205-cd205">DEC-205/CD205+</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1<sup>-/low</sup></a><br><a target="_blank" href="/target/f4-80">F4/80-</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207+</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a-</a><br><a target="_blank" href="/target/xcr1">XCR1+</a><br> </div> </div> <div id="el40_gry" class="dc_development_all pw-sprite el-gray40 pw-gray" style="top:882.6666870117188px;left:2.666748046875px;"> </div> <div id="el40_off" data-id="40" data-set="CD103-CD11b-CD207-DermalDC26" data-type="No Products Click" class="dc_development_all pw-sprite el-off40" style="top:882.6666870117188px;left:2.666748046875px;"> </div> <div id="el40_ct" class="pw-tooltip" data-id="40"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cd4">CD4-</a><br><a target="_blank" href="/target/cd8">CD8 alpha-</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd24">CD24-</a><br><a target="_blank" href="/target/integrin-alpha-e-cd103">CD103/Integrin alpha E-</a><br><a target="_blank" href="/target/clec9a">CLEC9a-</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1+</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1-</a><br><a target="_blank" href="/target/f4-80">F4/80+</a><br><a target="_blank" href="/target/fc-gamma-ri-cd64">Fc gamma RI/CD64+</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207-</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a+</a><br><a target="_blank" href="/target/xcr1">XCR1-</a><br> </div> </div> <div id="el41_gry" class="dc_development_all pw-label pw-center el-gray41 pw-gray" style="top:902.666748046875px;left:48px;"> CD103<sup>-</sup> CD11b<sup>+</sup> CD207<sup>-</sup><br>Dermal DC </div> <div id="el41_off" data-id="41" data-set="CD103-CD11b-CD207-DermalDC26" data-type="No Products Click" class="dc_development_all pw-label pw-center el-off41" style="top:902.666748046875px;left:48px;"> CD103<sup>-</sup> CD11b<sup>+</sup> CD207<sup>-</sup><br>Dermal DC</div> <div id="el41_ct" class="pw-tooltip" data-id="41"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cd4">CD4-</a><br><a target="_blank" href="/target/cd8">CD8 alpha-</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd24">CD24-</a><br><a target="_blank" href="/target/integrin-alpha-e-cd103">CD103/Integrin alpha E-</a><br><a target="_blank" href="/target/clec9a">CLEC9a-</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1+</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1-</a><br><a target="_blank" href="/target/f4-80">F4/80+</a><br><a target="_blank" href="/target/fc-gamma-ri-cd64">Fc gamma RI/CD64+</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207-</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a+</a><br><a target="_blank" href="/target/xcr1">XCR1-</a><br> </div> </div> <div id="el42_gry" class="dc_development_all pw-sprite el-gray42 pw-gray" style="top:920.666748046875px;left:26.666748046875px;"> </div> <div id="el42_off" data-id="42" data-set="CD103-CD11b-CD207-DermalDC27" data-type="No Products Click" class="dc_development_all pw-sprite el-off42" style="top:920.666748046875px;left:26.666748046875px;"> </div> <div id="el42_ct" class="pw-tooltip" data-id="42"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M<sup>-/low</sup></a><br><a target="_blank" href="/target/cd24">CD24+</a><br><a target="_blank" href="/target/integrin-alpha-e-cd103">CD103/Integrin alpha E-</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1<sup>-/low</sup></a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207+</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a-</a><br> </div> </div> <div id="el43_gry" class="dc_development_all pw-label pw-center el-gray43 pw-gray" style="top:940.666748046875px;left:74px;"> CD103<sup>-</sup> CD11b<sup>-</sup> CD207<sup>+</sup><br>Dermal DC </div> <div id="el43_off" data-id="43" data-set="CD103-CD11b-CD207-DermalDC27" data-type="No Products Click" class="dc_development_all pw-label pw-center el-off43" style="top:940.666748046875px;left:74px;"> CD103<sup>-</sup> CD11b<sup>-</sup> CD207<sup>+</sup><br>Dermal DC</div> <div id="el43_ct" class="pw-tooltip" data-id="43"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M<sup>-/low</sup></a><br><a target="_blank" href="/target/cd24">CD24+</a><br><a target="_blank" href="/target/integrin-alpha-e-cd103">CD103/Integrin alpha E-</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1<sup>-/low</sup></a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207+</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a-</a><br> </div> </div> <div id="el44_gry" class="dc_development_all pw-sprite el-gray44 pw-gray" style="top:957px;left:24px;"> </div> <div id="el44_off" data-id="44" data-set="CD103-CD11b-CD207-DermalDC28" data-type="No Products Click" class="dc_development_all pw-sprite el-off44" style="top:957px;left:24px;"> </div> <div id="el44_ct" class="pw-tooltip" data-id="44"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M<sup>-/low</sup></a><br><a target="_blank" href="/target/cd24">CD24-</a><br><a target="_blank" href="/target/integrin-alpha-e-cd103">CD103/Integrin alpha E-</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1-</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207-</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a<sup>-/low</sup></a><br> </div> </div> <div id="el45_gry" class="dc_development_all pw-label pw-center el-gray45 pw-gray" style="top:982px;left:61px;"> CD103<sup>-</sup> CD11b<sup>-</sup><br>CD207<sup>-</sup> Dermal DC </div> <div id="el45_off" data-id="45" data-set="CD103-CD11b-CD207-DermalDC28" data-type="No Products Click" class="dc_development_all pw-label pw-center el-off45" style="top:982px;left:61px;"> CD103<sup>-</sup> CD11b<sup>-</sup><br>CD207<sup>-</sup> Dermal DC</div> <div id="el45_ct" class="pw-tooltip" data-id="45"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M<sup>-/low</sup></a><br><a target="_blank" href="/target/cd24">CD24-</a><br><a target="_blank" href="/target/integrin-alpha-e-cd103">CD103/Integrin alpha E-</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1-</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207-</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a<sup>-/low</sup></a><br> </div> </div> <div id="el46_gry" class="dc_development_all pw-label2 pw-center el-gray46 pw-gray" style="top:804.6666870117188px;left:218px;"> Tissue Migratory/<br>Non-Lymphoid<br>Tissue cDCs </div> <div id="el46_off" data-id="46" data-set="TissueMigratoryNon-LymphoidTissuecDCs" data-type="" class="dc_development_all pw-label2 pw-center el-off46" style="top:804.6666870117188px;left:218px;"> Tissue Migratory/<br>Non-Lymphoid<br>Tissue cDCs</div> <div id="el46_ct" class="pw-tooltip" data-id="46"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el47_gry" class="dc_development_all pw-label2 pw-center el-gray47 pw-gray" style="top:734.6666870117188px;left:252px;"> Lymphoid Tissue-<br>Resident cDCs </div> <div id="el47_off" data-id="47" data-set="LymphoidTissue-ResidentcDCs" data-type="" class="dc_development_all pw-label2 pw-center el-off47" style="top:734.6666870117188px;left:252px;"> Lymphoid Tissue-<br>Resident cDCs</div> <div id="el47_ct" class="pw-tooltip" data-id="47"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el48_gry" class="dc_development_all pw-label2 el-gray48 pw-gray" style="top:1074.666748046875px;left:64px;"> Mouse Lung/Liver/Kidney </div> <div id="el48_off" data-id="48" data-set="MouseLungLiverKidney" data-type="" class="dc_development_all pw-label2 el-off48" style="top:1074.666748046875px;left:64px;"> Mouse Lung/Liver/Kidney</div> <div id="el48_ct" class="pw-tooltip" data-id="48"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el49_gry" class="dc_development_all pw-sprite el-gray49 pw-gray" style="top:1102.666748046875px;left:116.666748046875px;"> </div> <div id="el49_off" data-id="49" data-set="pDC32" data-type="" class="dc_development_all pw-sprite el-off49" style="top:1102.666748046875px;left:116.666748046875px;"> </div> <div id="el49_ct" class="pw-tooltip" data-id="49"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br><a target="_blank" href="/target/b220-cd45r">B220/CD45 R+</a><br><a target="_blank" href="/target/bst-2-tetherin">Bst-2/PDCA-1+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M-</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/clec9a">CLEC9a+</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br>Ly-6C+<br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/siglec-h">Siglec-H+</a><br><strong>Intracellular Markers</strong><br>E2-2/Tcf4+<br>IRF7+<br><a target="_blank" href="/target/irf8">IRF8+</a><br><a target="_blank" href="/target/spi-b">Spi-B+</a><br><a target="_blank" href="/target/tlr7">TLR7+</a><br><a target="_blank" href="/target/tlr9">TLR9+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/ifn-alpha">IFN-alpha</a><br><a target="_blank" href="/target/ifn-beta">IFN-beta</a><br><a target="_blank" href="/target/il-6">IL-6</a><br><a target="_blank" href="/target/tnf-alpha">TNF-alpha</a><br> </div> </div> <div id="el50_gry" class="dc_development_all pw-label el-gray50 pw-gray" style="top:1130.666748046875px;left:122px;"> pDC </div> <div id="el50_off" data-id="50" data-set="pDC32" data-type="No Products Click" class="dc_development_all pw-label el-off50" style="top:1130.666748046875px;left:122px;"> pDC</div> <div id="el50_ct" class="pw-tooltip" data-id="50"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br><a target="_blank" href="/target/b220-cd45r">B220/CD45 R+</a><br><a target="_blank" href="/target/bst-2-tetherin">Bst-2/PDCA-1+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M-</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/clec9a">CLEC9a+</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br>Ly-6C+<br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/siglec-h">Siglec-H+</a><br><strong>Intracellular Markers</strong><br>E2-2/Tcf4+<br>IRF7+<br><a target="_blank" href="/target/irf8">IRF8+</a><br><a target="_blank" href="/target/spi-b">Spi-B+</a><br><a target="_blank" href="/target/tlr7">TLR7+</a><br><a target="_blank" href="/target/tlr9">TLR9+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/ifn-alpha">IFN-alpha</a><br><a target="_blank" href="/target/ifn-beta">IFN-beta</a><br><a target="_blank" href="/target/il-6">IL-6</a><br><a target="_blank" href="/target/tnf-alpha">TNF-alpha</a><br> </div> </div> <div id="el51_gry" class="dc_development_all pw-sprite el-gray51 pw-gray" style="top:1150.666748046875px;left:68.666748046875px;"> </div> <div id="el51_off" data-id="51" data-set="CD103-CD11b-cDC33" data-type="No Products Click" class="dc_development_all pw-sprite el-off51" style="top:1150.666748046875px;left:68.666748046875px;"> </div> <div id="el51_ct" class="pw-tooltip" data-id="51"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cd4">CD4-</a><br><a target="_blank" href="/target/cd8">CD8 alpha-</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd24">CD24+/-</a><br><a target="_blank" href="/target/integrin-alpha-e-cd103">CD103/Integrin alpha E-</a><br><a target="_blank" href="/target/clec9a">CLEC9a-</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1+</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1-</a><br><a target="_blank" href="/target/f4-80">F4/80+</a><br><a target="_blank" href="/target/fc-gamma-ri-cd64">Fc gamma RI/CD64+</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207-</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a+</a><br><a target="_blank" href="/target/xcr1">XCR1-</a><br> </div> </div> <div id="el52_gry" class="dc_development_all pw-label pw-center el-gray52 pw-gray" style="top:1158px;left:120px;"> CD103<sup>-</sup><br>CD11b<sup>+</sup> cDC </div> <div id="el52_off" data-id="52" data-set="CD103-CD11b-cDC33" data-type="No Products Click" class="dc_development_all pw-label pw-center el-off52" style="top:1158px;left:120px;"> CD103<sup>-</sup><br>CD11b<sup>+</sup> cDC</div> <div id="el52_ct" class="pw-tooltip" data-id="52"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cd4">CD4-</a><br><a target="_blank" href="/target/cd8">CD8 alpha-</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd24">CD24+/-</a><br><a target="_blank" href="/target/integrin-alpha-e-cd103">CD103/Integrin alpha E-</a><br><a target="_blank" href="/target/clec9a">CLEC9a-</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1+</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1-</a><br><a target="_blank" href="/target/f4-80">F4/80+</a><br><a target="_blank" href="/target/fc-gamma-ri-cd64">Fc gamma RI/CD64+</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207-</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a+</a><br><a target="_blank" href="/target/xcr1">XCR1-</a><br> </div> </div> <div id="el53_gry" class="dc_development_all pw-sprite el-gray53 pw-gray" style="top:1196.6667175292969px;left:68.666748046875px;"> </div> <div id="el53_off" data-id="53" data-set="CD103-CD11b-cDC34" data-type="No Products Click" class="dc_development_all pw-sprite el-off53" style="top:1196.6667175292969px;left:68.666748046875px;"> </div> <div id="el53_ct" class="pw-tooltip" data-id="53"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cd4">CD4-</a><br><a target="_blank" href="/target/cd8">CD8 alpha-</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M-</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd24">CD24+</a><br><a target="_blank" href="/target/integrin-alpha-e-cd103">CD103/Integrin alpha E+</a><br><a target="_blank" href="/target/clec9a">CLEC9a+</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1-</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209-</a><br><a target="_blank" href="/target/dec-205-cd205">DEC-205/CD205+</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1-</a><br><a target="_blank" href="/target/f4-80">F4/80-</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207+</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a-</a><br><a target="_blank" href="/target/xcr1">XCR1+</a><br> </div> </div> <div id="el54_gry" class="dc_development_all pw-label pw-center el-gray54 pw-gray" style="top:1206px;left:119px;"> CD103<sup>+</sup><br>CD11b<sup>-</sup> cDC </div> <div id="el54_off" data-id="54" data-set="CD103-CD11b-cDC34" data-type="No Products Click" class="dc_development_all pw-label pw-center el-off54" style="top:1206px;left:119px;"> CD103<sup>+</sup><br>CD11b<sup>-</sup> cDC</div> <div id="el54_ct" class="pw-tooltip" data-id="54"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cd4">CD4-</a><br><a target="_blank" href="/target/cd8">CD8 alpha-</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M-</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd24">CD24+</a><br><a target="_blank" href="/target/integrin-alpha-e-cd103">CD103/Integrin alpha E+</a><br><a target="_blank" href="/target/clec9a">CLEC9a+</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1-</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209-</a><br><a target="_blank" href="/target/dec-205-cd205">DEC-205/CD205+</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1-</a><br><a target="_blank" href="/target/f4-80">F4/80-</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207+</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a-</a><br><a target="_blank" href="/target/xcr1">XCR1+</a><br> </div> </div> <div id="el55_gry" class="dc_development_all pw-label2 pw-center el-gray55 pw-gray" style="top:962.6667022705078px;left:291px;"> Mouse<br>Lymphoid Tissue </div> <div id="el55_off" data-id="55" data-set="MouseLymphoidTissue" data-type="" class="dc_development_all pw-label2 pw-center el-off55" style="top:962.6667022705078px;left:291px;"> Mouse<br>Lymphoid Tissue</div> <div id="el55_ct" class="pw-tooltip" data-id="55"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el56_gry" class="dc_development_all pw-sprite el-gray56 pw-gray" style="top:1006.6667022705078px;left:332.666748046875px;"> </div> <div id="el56_off" data-id="56" data-set="pDC36" data-type="" class="dc_development_all pw-sprite el-off56" style="top:1006.6667022705078px;left:332.666748046875px;"> </div> <div id="el56_ct" class="pw-tooltip" data-id="56"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br><a target="_blank" href="/target/b220-cd45r">B220/CD45 R+</a><br><a target="_blank" href="/target/bst-2-tetherin">Bst-2/PDCA-1+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M-</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/clec9a">CLEC9a+</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br>Ly-6C+<br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/siglec-h">Siglec-H+</a><br><strong>Intracellular Markers</strong><br>E2-2/Tcf4+<br>IRF7+<br><a target="_blank" href="/target/irf8">IRF8+</a><br><a target="_blank" href="/target/spi-b">Spi-B+</a><br><a target="_blank" href="/target/tlr7">TLR7+</a><br><a target="_blank" href="/target/tlr9">TLR9+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/ifn-alpha">IFN-alpha</a><br><a target="_blank" href="/target/ifn-beta">IFN-beta</a><br><a target="_blank" href="/target/il-6">IL-6</a><br><a target="_blank" href="/target/tnf-alpha">TNF-alpha</a><br> </div> </div> <div id="el57_gry" class="dc_development_all pw-label el-gray57 pw-gray" style="top:1017.6667022705078px;left:302px;"> pDC </div> <div id="el57_off" data-id="57" data-set="pDC36" data-type="No Products Click" class="dc_development_all pw-label el-off57" style="top:1017.6667022705078px;left:302px;"> pDC</div> <div id="el57_ct" class="pw-tooltip" data-id="57"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br><a target="_blank" href="/target/b220-cd45r">B220/CD45 R+</a><br><a target="_blank" href="/target/bst-2-tetherin">Bst-2/PDCA-1+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M-</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/clec9a">CLEC9a+</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br>Ly-6C+<br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/siglec-h">Siglec-H+</a><br><strong>Intracellular Markers</strong><br>E2-2/Tcf4+<br>IRF7+<br><a target="_blank" href="/target/irf8">IRF8+</a><br><a target="_blank" href="/target/spi-b">Spi-B+</a><br><a target="_blank" href="/target/tlr7">TLR7+</a><br><a target="_blank" href="/target/tlr9">TLR9+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/ifn-alpha">IFN-alpha</a><br><a target="_blank" href="/target/ifn-beta">IFN-beta</a><br><a target="_blank" href="/target/il-6">IL-6</a><br><a target="_blank" href="/target/tnf-alpha">TNF-alpha</a><br> </div> </div> <div id="el58_gry" class="dc_development_all pw-sprite el-gray58 pw-gray" style="top:1050.6667022705078px;left:364.666748046875px;"> </div> <div id="el58_off" data-id="58" data-set="CD8alpha-cDC37" data-type="No Products Click" class="dc_development_all pw-sprite el-off58" style="top:1050.6667022705078px;left:364.666748046875px;"> </div> <div id="el58_ct" class="pw-tooltip" data-id="58"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br><a target="_blank" href="/target/cd4">CD4-</a><br><a target="_blank" href="/target/cd8">CD8 alpha+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M-</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd24">CD24+</a><br><a target="_blank" href="/target/integrin-alpha-e-cd103">CD103/Integrin alpha E+/-</a><br><a target="_blank" href="/target/clec9a">CLEC9a+</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209-</a><br><a target="_blank" href="/target/dec-205-cd205">DEC-205/CD205+</a><br><a target="_blank" href="/target/f4-80">F4/80-</a><br><a target="_blank" href="/target/igsf4a-syncam1">IGSF4A/SynCAM1/Necl2+</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207+/-</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a-</a><br><a target="_blank" href="/target/xcr1">XCR1+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/il-12">IL-12</a><br> </div> </div> <div id="el59_gry" class="dc_development_all pw-label el-gray59 pw-gray" style="top:1058px;left:270px;"> CD8 alpha<sup>+</sup> cDC </div> <div id="el59_off" data-id="59" data-set="CD8alpha-cDC37" data-type="No Products Click" class="dc_development_all pw-label el-off59" style="top:1058px;left:270px;"> CD8 alpha<sup>+</sup> cDC</div> <div id="el59_ct" class="pw-tooltip" data-id="59"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br><a target="_blank" href="/target/cd4">CD4-</a><br><a target="_blank" href="/target/cd8">CD8 alpha+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M-</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd24">CD24+</a><br><a target="_blank" href="/target/integrin-alpha-e-cd103">CD103/Integrin alpha E+/-</a><br><a target="_blank" href="/target/clec9a">CLEC9a+</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209-</a><br><a target="_blank" href="/target/dec-205-cd205">DEC-205/CD205+</a><br><a target="_blank" href="/target/f4-80">F4/80-</a><br><a target="_blank" href="/target/igsf4a-syncam1">IGSF4A/SynCAM1/Necl2+</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207+/-</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a-</a><br><a target="_blank" href="/target/xcr1">XCR1+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/il-12">IL-12</a><br> </div> </div> <div id="el60_gry" class="dc_development_all pw-sprite el-gray60 pw-gray" style="top:1090px;left:273px;"> </div> <div id="el60_off" data-id="60" data-set="CD11b-cDC38" data-type="No Products Click" class="dc_development_all pw-sprite el-off60" style="top:1090px;left:273px;"> </div> <div id="el60_ct" class="pw-tooltip" data-id="60"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br><a target="_blank" href="/target/cd4">CD4+/-</a><br><a target="_blank" href="/target/cd8">CD8 alpha-</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd24">CD24+</a><br><a target="_blank" href="/target/clec9a">CLEC9a-</a><br>DCIR2+<br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209+</a><br><a target="_blank" href="/target/dec-205-cd205">DEC-205/CD205+</a><br><a target="_blank" href="/target/f4-80">F4/80+</a><br><a target="_blank" href="/target/igsf4a-syncam1">IGSF4A/SynCAM1/Necl2-</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207-</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a+</a><br><a target="_blank" href="/target/xcr1">XCR1-</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/ifn-gamma">IFN-gamma</a><br><a target="_blank" href="/target/il-2">IL-2</a><br><a target="_blank" href="/target/il-6">IL-6</a><br> </div> </div> <div id="el61_gry" class="dc_development_all pw-label el-gray61 pw-gray" style="top:1108px;left:320px;"> CD11b<sup>+</sup> cDC </div> <div id="el61_off" data-id="61" data-set="CD11b-cDC38" data-type="No Products Click" class="dc_development_all pw-label el-off61" style="top:1108px;left:320px;"> CD11b<sup>+</sup> cDC</div> <div id="el61_ct" class="pw-tooltip" data-id="61"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br><a target="_blank" href="/target/cd4">CD4+/-</a><br><a target="_blank" href="/target/cd8">CD8 alpha-</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd24">CD24+</a><br><a target="_blank" href="/target/clec9a">CLEC9a-</a><br>DCIR2+<br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209+</a><br><a target="_blank" href="/target/dec-205-cd205">DEC-205/CD205+</a><br><a target="_blank" href="/target/f4-80">F4/80+</a><br><a target="_blank" href="/target/igsf4a-syncam1">IGSF4A/SynCAM1/Necl2-</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207-</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a+</a><br><a target="_blank" href="/target/xcr1">XCR1-</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/ifn-gamma">IFN-gamma</a><br><a target="_blank" href="/target/il-2">IL-2</a><br><a target="_blank" href="/target/il-6">IL-6</a><br> </div> </div> <div id="el62_gry" class="dc_development_all pw-label2 pw-center el-gray62 pw-gray" style="top:1216.666748046875px;left:268px;"> Mouse Intestinal Lamina<br>Propria/Peyer's Patch </div> <div id="el62_off" data-id="62" data-set="MouseIntestinalLaminaPropriaPeyer" data-type="" class="dc_development_all pw-label2 pw-center el-off62" style="top:1216.666748046875px;left:268px;"> Mouse Intestinal Lamina<br>Propria/Peyer's Patch</div> <div id="el62_ct" class="pw-tooltip" data-id="62"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el63_gry" class="dc_development_all pw-sprite el-gray63 pw-gray" style="top:1265.6667175292969px;left:280.666748046875px;"> </div> <div id="el63_off" data-id="63" data-set="CD103-CD11b-cDC40" data-type="" class="dc_development_all pw-sprite el-off63" style="top:1265.6667175292969px;left:280.666748046875px;"> </div> <div id="el63_ct" class="pw-tooltip" data-id="63"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cd4">CD4-</a><br><a target="_blank" href="/target/cd8">CD8 alpha-</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M-</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd24">CD24+</a><br><a target="_blank" href="/target/integrin-alpha-e-cd103">CD103/Integrin alpha E+</a><br><a target="_blank" href="/target/clec9a">CLEC9a+</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1-</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209-</a><br><a target="_blank" href="/target/dec-205-cd205">DEC-205/CD205+</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1-</a><br><a target="_blank" href="/target/f4-80">F4/80-</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207+</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a-</a><br><a target="_blank" href="/target/xcr1">XCR1+</a><br> </div> </div> <div id="el64_gry" class="dc_development_all pw-label pw-center el-gray64 pw-gray" style="top:1272px;left:331px;"> CD103<sup>+</sup><br>CD11b<sup>-</sup> cDC </div> <div id="el64_off" data-id="64" data-set="CD103-CD11b-cDC40" data-type="No Products Click" class="dc_development_all pw-label pw-center el-off64" style="top:1272px;left:331px;"> CD103<sup>+</sup><br>CD11b<sup>-</sup> cDC</div> <div id="el64_ct" class="pw-tooltip" data-id="64"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cd4">CD4-</a><br><a target="_blank" href="/target/cd8">CD8 alpha-</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M-</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd24">CD24+</a><br><a target="_blank" href="/target/integrin-alpha-e-cd103">CD103/Integrin alpha E+</a><br><a target="_blank" href="/target/clec9a">CLEC9a+</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1-</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209-</a><br><a target="_blank" href="/target/dec-205-cd205">DEC-205/CD205+</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1-</a><br><a target="_blank" href="/target/f4-80">F4/80-</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207+</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a-</a><br><a target="_blank" href="/target/xcr1">XCR1+</a><br> </div> </div> <div id="el65_gry" class="dc_development_all pw-sprite el-gray65 pw-gray" style="top:1316.6667175292969px;left:250.666748046875px;"> </div> <div id="el65_off" data-id="65" data-set="CD103-CD11b-cDC41" data-type="No Products Click" class="dc_development_all pw-sprite el-off65" style="top:1316.6667175292969px;left:250.666748046875px;"> </div> <div id="el65_ct" class="pw-tooltip" data-id="65"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cd4">CD4-</a><br><a target="_blank" href="/target/cd8">CD8 alpha-</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd24">CD24+/-</a><br><a target="_blank" href="/target/integrin-alpha-e-cd103">CD103/Integrin alpha E-</a><br><a target="_blank" href="/target/clec9a">CLEC9a-</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1+</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1-</a><br><a target="_blank" href="/target/f4-80">F4/80+</a><br><a target="_blank" href="/target/fc-gamma-ri-cd64">Fc gamma RI/CD64+</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207-</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a+</a><br><a target="_blank" href="/target/xcr1">XCR1-</a><br> </div> </div> <div id="el66_gry" class="dc_development_all pw-label pw-center el-gray66 pw-gray" style="top:1321.6667175292969px;left:298px;"> CD103<sup>-</sup> CD11b<sup>+</sup><br>cDC </div> <div id="el66_off" data-id="66" data-set="CD103-CD11b-cDC41" data-type="No Products Click" class="dc_development_all pw-label pw-center el-off66" style="top:1321.6667175292969px;left:298px;"> CD103<sup>-</sup> CD11b<sup>+</sup><br>cDC</div> <div id="el66_ct" class="pw-tooltip" data-id="66"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cd4">CD4-</a><br><a target="_blank" href="/target/cd8">CD8 alpha-</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd24">CD24+/-</a><br><a target="_blank" href="/target/integrin-alpha-e-cd103">CD103/Integrin alpha E-</a><br><a target="_blank" href="/target/clec9a">CLEC9a-</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1+</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1-</a><br><a target="_blank" href="/target/f4-80">F4/80+</a><br><a target="_blank" href="/target/fc-gamma-ri-cd64">Fc gamma RI/CD64+</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207-</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a+</a><br><a target="_blank" href="/target/xcr1">XCR1-</a><br> </div> </div> <div id="el67_gry" class="dc_development_all pw-sprite el-gray67 pw-gray" style="top:1357.6667175292969px;left:300.666748046875px;"> </div> <div id="el67_off" data-id="67" data-set="CD103-CD11b-cDC42" data-type="No Products Click" class="dc_development_all pw-sprite el-off67" style="top:1357.6667175292969px;left:300.666748046875px;"> </div> <div id="el67_ct" class="pw-tooltip" data-id="67"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cd4">CD4-</a><br><a target="_blank" href="/target/cd8">CD8 alpha-</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd24">CD24+</a><br><a target="_blank" href="/target/integrin-alpha-e-cd103">CD103/Integrin alpha E+</a><br><a target="_blank" href="/target/clec9a">CLEC9a-</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1-</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209+</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1-</a><br><a target="_blank" href="/target/f4-80">F4/80-</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207-</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a-</a><br><a target="_blank" href="/target/xcr1">XCR1-</a><br> </div> </div> <div id="el68_gry" class="dc_development_all pw-label pw-center el-gray68 pw-gray" style="top:1402.6667175292969px;left:300px;"> CD103<sup>+</sup> CD11b<sup>+</sup><br>cDC </div> <div id="el68_off" data-id="68" data-set="CD103-CD11b-cDC42" data-type="No Products Click" class="dc_development_all pw-label pw-center el-off68" style="top:1402.6667175292969px;left:300px;"> CD103<sup>+</sup> CD11b<sup>+</sup><br>cDC</div> <div id="el68_ct" class="pw-tooltip" data-id="68"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cd4">CD4-</a><br><a target="_blank" href="/target/cd8">CD8 alpha-</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd24">CD24+</a><br><a target="_blank" href="/target/integrin-alpha-e-cd103">CD103/Integrin alpha E+</a><br><a target="_blank" href="/target/clec9a">CLEC9a-</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1-</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209+</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1-</a><br><a target="_blank" href="/target/f4-80">F4/80-</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207-</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a-</a><br><a target="_blank" href="/target/xcr1">XCR1-</a><br> </div> </div> <div id="el69_gry" class="dc_development_all pw-sprite el-gray69 pw-gray" style="top:1348.6667175292969px;left:386.666748046875px;"> </div> <div id="el69_off" data-id="69" data-set="pDC43" data-type="No Products Click" class="dc_development_all pw-sprite el-off69" style="top:1348.6667175292969px;left:386.666748046875px;"> </div> <div id="el69_ct" class="pw-tooltip" data-id="69"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br><a target="_blank" href="/target/b220-cd45r">B220/CD45 R+</a><br><a target="_blank" href="/target/bst-2-tetherin">Bst-2/PDCA-1+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M-</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/clec9a">CLEC9a+</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br>Ly-6C+<br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/siglec-h">Siglec-H+</a><br><strong>Intracellular Markers</strong><br>E2-2/Tcf4+<br>IRF7+<br><a target="_blank" href="/target/irf8">IRF8+</a><br><a target="_blank" href="/target/spi-b">Spi-B+</a><br><a target="_blank" href="/target/tlr7">TLR7+</a><br><a target="_blank" href="/target/tlr9">TLR9+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/ifn-alpha">IFN-alpha</a><br><a target="_blank" href="/target/ifn-beta">IFN-beta</a><br><a target="_blank" href="/target/il-6">IL-6</a><br><a target="_blank" href="/target/tnf-alpha">TNF-alpha</a><br> </div> </div> <div id="el70_gry" class="dc_development_all pw-label el-gray70 pw-gray" style="top:1336.6667175292969px;left:400px;"> pDC </div> <div id="el70_off" data-id="70" data-set="pDC43" data-type="No Products Click" class="dc_development_all pw-label el-off70" style="top:1336.6667175292969px;left:400px;"> pDC</div> <div id="el70_ct" class="pw-tooltip" data-id="70"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br><a target="_blank" href="/target/b220-cd45r">B220/CD45 R+</a><br><a target="_blank" href="/target/bst-2-tetherin">Bst-2/PDCA-1+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M-</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/clec9a">CLEC9a+</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209+</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br>Ly-6C+<br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/siglec-h">Siglec-H+</a><br><strong>Intracellular Markers</strong><br>E2-2/Tcf4+<br>IRF7+<br><a target="_blank" href="/target/irf8">IRF8+</a><br><a target="_blank" href="/target/spi-b">Spi-B+</a><br><a target="_blank" href="/target/tlr7">TLR7+</a><br><a target="_blank" href="/target/tlr9">TLR9+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/ifn-alpha">IFN-alpha</a><br><a target="_blank" href="/target/ifn-beta">IFN-beta</a><br><a target="_blank" href="/target/il-6">IL-6</a><br><a target="_blank" href="/target/tnf-alpha">TNF-alpha</a><br> </div> </div> <div id="el71_gry" class="dc_development_all pw-label2 pw-center el-gray71 pw-gray" style="top:1052.666748046875px;left:492px;"> Peripheral Tissues & <br>Draining Lymph Nodes<br>During Inflammation </div> <div id="el71_off" data-id="71" data-set="PeripheralTissuesDrainingLymphNodesDuringInflammation" data-type="" class="dc_development_all pw-label2 pw-center el-off71" style="top:1052.666748046875px;left:492px;"> Peripheral Tissues & <br>Draining Lymph Nodes<br>During Inflammation</div> <div id="el71_ct" class="pw-tooltip" data-id="71"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el72_gry" class="dc_development_all pw-sprite el-gray72 pw-gray" style="top:1112.666748046875px;left:526.666748046875px;"> </div> <div id="el72_off" data-id="72" data-set="MouseInflammatoryMonocyte-derivedDC45" data-type="" class="dc_development_all pw-sprite el-off72" style="top:1112.666748046875px;left:526.666748046875px;"> </div> <div id="el72_ct" class="pw-tooltip" data-id="72"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/lamp-2-cd107b">CD107b/Mac-3+</a><br><a target="_blank" href="/target/f4-80">F4/80+</a><br><a target="_blank" href="/target/fc-gamma-ri-cd64">Fc gamma RI/CD64+</a><br><a target="_blank" href="/target/fc-epsilon-ri-alpha">Fc epsilon RI+</a><br>Ly-6C+<br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/mmr-cd206">MMR/CD206+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/il-12">IL-12</a><br><a target="_blank" href="/target/nitric-oxide">NO</a><br><a target="_blank" href="/target/tnf-alpha">TNF-alpha</a><br> </div> </div> <div id="el73_gry" class="dc_development_all pw-label pw-center el-gray73 pw-gray" style="top:1156px;left:512px;"> Mouse<br>Inflammatory<br>Monocyte-<br>derived DC </div> <div id="el73_off" data-id="73" data-set="MouseInflammatoryMonocyte-derivedDC45" data-type="No Products Click" class="dc_development_all pw-label pw-center el-off73" style="top:1156px;left:512px;"> Mouse<br>Inflammatory<br>Monocyte-<br>derived DC</div> <div id="el73_ct" class="pw-tooltip" data-id="73"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/lamp-2-cd107b">CD107b/Mac-3+</a><br><a target="_blank" href="/target/f4-80">F4/80+</a><br><a target="_blank" href="/target/fc-gamma-ri-cd64">Fc gamma RI/CD64+</a><br><a target="_blank" href="/target/fc-epsilon-ri-alpha">Fc epsilon RI+</a><br>Ly-6C+<br><a target="_blank" href="/target/mhc-class-ii-i-a-i-e">MHC class II+</a><br><a target="_blank" href="/target/mmr-cd206">MMR/CD206+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/il-12">IL-12</a><br><a target="_blank" href="/target/nitric-oxide">NO</a><br><a target="_blank" href="/target/tnf-alpha">TNF-alpha</a><br> </div> </div> <div id="el74_gry" class="dc_development_all pw-label2 el-gray74 pw-gray" style="top:92px;left:508px;"> Human </div> <div id="el74_off" data-id="74" data-set="Human" data-type="" class="dc_development_all pw-label2 el-off74" style="top:92px;left:508px;"> Human</div> <div id="el74_ct" class="pw-tooltip" data-id="74"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el75_gry" class="dc_development_all pw-sprite el-gray75 pw-gray" style="top:152.6666717529297px;left:524.666748046875px;"> </div> <div id="el75_off" data-id="75" data-set="HematopoieticStemCell-HSC-47" data-type="" class="dc_development_all pw-sprite el-off75" style="top:152.6666717529297px;left:524.666748046875px;"> </div> <div id="el75_ct" class="pw-tooltip" data-id="75"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd34">CD34+</a><br><a target="_blank" href="/target/cd38">CD38-</a><br>CD45RA-<br>CD49f+<br><a target="_blank" href="/target/cd90-thy1">CD90/Thy1+</a><br> </div> </div> <div id="el76_gry" class="dc_development_all pw-label el-gray76 pw-gray" style="top:153px;left:564px;"> Hematopoietic Stem Cell (HSC) </div> <div id="el76_off" data-id="76" data-set="HematopoieticStemCell-HSC-47" data-type="No Products Click" class="dc_development_all pw-label el-off76" style="top:153px;left:564px;"> Hematopoietic Stem Cell (HSC)</div> <div id="el76_ct" class="pw-tooltip" data-id="76"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd34">CD34+</a><br><a target="_blank" href="/target/cd38">CD38-</a><br>CD45RA-<br>CD49f+<br><a target="_blank" href="/target/cd90-thy1">CD90/Thy1+</a><br> </div> </div> <div id="el77_gry" class="dc_development_all pw-sprite el-gray77 pw-gray" style="top:200.6666717529297px;left:508.666748046875px;"> </div> <div id="el77_off" data-id="77" data-set="Multi-lymphoidProgenitor-MLP-48" data-type="No Products Click" class="dc_development_all pw-sprite el-off77" style="top:200.6666717529297px;left:508.666748046875px;"> </div> <div id="el77_ct" class="pw-tooltip" data-id="77"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd7">CD7-</a><br><a target="_blank" href="/target/neprilysin-cd10">CD10/Neprilysin+</a><br><a target="_blank" href="/target/cd34">CD34+</a><br><a target="_blank" href="/target/cd38">CD38-</a><br>CD45RA+<br><a target="_blank" href="/target/cd90-thy1">CD90/Thy1<sup>-/low</sup></a><br> </div> </div> <div id="el78_gry" class="dc_development_all pw-label pw-right el-gray78 pw-gray" style="top:202px;left:404px;"> Multi-lymphoid<br>Progenitor (MLP) </div> <div id="el78_off" data-id="78" data-set="Multi-lymphoidProgenitor-MLP-48" data-type="No Products Click" class="dc_development_all pw-label pw-right el-off78" style="top:202px;left:404px;"> Multi-lymphoid<br>Progenitor (MLP)</div> <div id="el78_ct" class="pw-tooltip" data-id="78"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd7">CD7-</a><br><a target="_blank" href="/target/neprilysin-cd10">CD10/Neprilysin+</a><br><a target="_blank" href="/target/cd34">CD34+</a><br><a target="_blank" href="/target/cd38">CD38-</a><br>CD45RA+<br><a target="_blank" href="/target/cd90-thy1">CD90/Thy1<sup>-/low</sup></a><br> </div> </div> <div id="el79_gry" class="dc_development_all pw-sprite el-gray79 pw-gray" style="top:200.6666717529297px;left:544.666748046875px;"> </div> <div id="el79_off" data-id="79" data-set="Granulocyte-MacrophageProgenitor-GMP-49" data-type="No Products Click" class="dc_development_all pw-sprite el-off79" style="top:200.6666717529297px;left:544.666748046875px;"> </div> <div id="el79_ct" class="pw-tooltip" data-id="79"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1-</a><br><a target="_blank" href="/target/cd7">CD7-</a><br><a target="_blank" href="/target/neprilysin-cd10">CD10/Neprilysin-</a><br><a target="_blank" href="/target/cd34">CD34+</a><br><a target="_blank" href="/target/cd38">CD38+</a><br>CD45RA+<br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit+</a><br><a target="_blank" href="/target/thrombomodulin-bdca-3">CD141/BDCA-3-</a><br><a target="_blank" href="/target/dlec-clec4c-bdca-2">DLEC/BDCA-2-</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br><a target="_blank" href="/target/gm-csf-r-alpha">GM-CSF R-</a><br><a target="_blank" href="/target/il-3-r-alpha-cd123">IL-3 R alpha/CD123<sup>int</sup></a><br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115-</a><br> </div> </div> <div id="el80_gry" class="dc_development_all pw-label el-gray80 pw-gray" style="top:202px;left:581px;"> Granulocyte-Macrophage Progenitor (GMP) </div> <div id="el80_off" data-id="80" data-set="Granulocyte-MacrophageProgenitor-GMP-49" data-type="No Products Click" class="dc_development_all pw-label el-off80" style="top:202px;left:581px;"> Granulocyte-Macrophage Progenitor (GMP)</div> <div id="el80_ct" class="pw-tooltip" data-id="80"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1-</a><br><a target="_blank" href="/target/cd7">CD7-</a><br><a target="_blank" href="/target/neprilysin-cd10">CD10/Neprilysin-</a><br><a target="_blank" href="/target/cd34">CD34+</a><br><a target="_blank" href="/target/cd38">CD38+</a><br>CD45RA+<br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit+</a><br><a target="_blank" href="/target/thrombomodulin-bdca-3">CD141/BDCA-3-</a><br><a target="_blank" href="/target/dlec-clec4c-bdca-2">DLEC/BDCA-2-</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br><a target="_blank" href="/target/gm-csf-r-alpha">GM-CSF R-</a><br><a target="_blank" href="/target/il-3-r-alpha-cd123">IL-3 R alpha/CD123<sup>int</sup></a><br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115-</a><br> </div> </div> <div id="el81_gry" class="dc_development_all pw-sprite el-gray81 pw-gray" style="top:252.66668701171875px;left:522.666748046875px;"> </div> <div id="el81_off" data-id="81" data-set="HumanEquivalentofMDPorCDP50" data-type="No Products Click" class="dc_development_all pw-sprite el-off81" style="top:252.66668701171875px;left:522.666748046875px;"> </div> <div id="el81_ct" class="pw-tooltip" data-id="81"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>MDP</strong><br>Lin-<br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1-</a><br><a target="_blank" href="/target/cd34">CD34+</a><br>CD45RA+<br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit+</a><br><a target="_blank" href="/target/thrombomodulin-bdca-3">CD141/BDCA-3-</a><br><a target="_blank" href="/target/dlec-clec4c-bdca-2">DLEC/BDCA-2-</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br><a target="_blank" href="/target/gm-csf-r-alpha">GM-CSF R-</a><br><a target="_blank" href="/target/il-3-r-alpha-cd123">IL-3 R alpha/CD123<sup>low/int</sup><br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br><strong>CDP</strong><br> Lin-<br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1-</a><br><a target="_blank" href="/target/cd34">CD34+</a><br>CD45RA+<br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit+</a><br><a target="_blank" href="/target/thrombomodulin-bdca-3">CD141/BDCA-3-</a><br><a target="_blank" href="/target/dlec-clec4c-bdca-2">DLEC/BDCA-2-</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br> <a target="_blank" href="/target/gm-csf-r-alpha">GM-CSF R+</a><br><a target="_blank" href="/target/il-3-r-alpha-cd123">IL-3 R alpha/CD123<sup>high</sup></a><br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115-</a><br> </div> </div> <div id="el82_gry" class="dc_development_all pw-label el-gray82 pw-gray" style="top:253px;left:560px;"> Human Equivalent of<br>MDP or CDP </div> <div id="el82_off" data-id="82" data-set="HumanEquivalentofMDPorCDP50" data-type="No Products Click" class="dc_development_all pw-label el-off82" style="top:253px;left:560px;"> Human Equivalent of<br>MDP or CDP</div> <div id="el82_ct" class="pw-tooltip" data-id="82"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>MDP</strong><br>Lin-<br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1-</a><br><a target="_blank" href="/target/cd34">CD34+</a><br>CD45RA+<br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit+</a><br><a target="_blank" href="/target/thrombomodulin-bdca-3">CD141/BDCA-3-</a><br><a target="_blank" href="/target/dlec-clec4c-bdca-2">DLEC/BDCA-2-</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br><a target="_blank" href="/target/gm-csf-r-alpha">GM-CSF R-</a><br><a target="_blank" href="/target/il-3-r-alpha-cd123">IL-3 R alpha/CD123<sup>low/int</sup></a><br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115+</a><br><strong>CDP</strong><br> Lin-<br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1-</a><br><a target="_blank" href="/target/cd34">CD34+</a><br>CD45RA+<br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit+</a><br><a target="_blank" href="/target/thrombomodulin-bdca-3">CD141/BDCA-3-</a><br><a target="_blank" href="/target/dlec-clec4c-bdca-2">DLEC/BDCA-2-</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br> <a target="_blank" href="/target/gm-csf-r-alpha">GM-CSF R+</a><br><a target="_blank" href="/target/il-3-r-alpha-cd123">IL-3 R alpha/CD123<sup>high</sup></a><br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115-</a><br> </div> </div> <div id="el83_gry" class="dc_development_all pw-label2 el-gray83 pw-gray" style="top:252.66668701171875px;left:396px;"> Common Monocyte<br>Progenitor (cMoP) </div> <div id="el83_off" data-id="83" data-set="CommonMonocyteProgenitor-cMoP" data-type="" class="dc_development_all pw-label2 el-off83" style="top:252.66668701171875px;left:396px;"> Common Monocyte<br>Progenitor (cMoP)</div> <div id="el83_ct" class="pw-tooltip" data-id="83"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el84_gry" class="dc_development_all pw-sprite el-gray84 pw-gray" style="top:330.66668701171875px;left:406.666748046875px;"> </div> <div id="el84_off" data-id="84" data-set="Monocyte52" data-type="" class="dc_development_all pw-sprite el-off84" style="top:330.66668701171875px;left:406.666748046875px;"> </div> <div id="el84_ct" class="pw-tooltip" data-id="84"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/ccr2">CCR2-/+</a><br><a target="_blank" href="/target/ccr5">CCR5-/+</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1-/+</a><br><a target="_blank" href="/target/cd14">CD14+</a><br><a target="_blank" href="/target/fc-gamma-riii-cd16">Fc gamma RIII/CD16-/+</a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br> </div> </div> <div id="el85_gry" class="dc_development_all pw-label el-gray85 pw-gray" style="top:314.66668701171875px;left:386px;"> Monocyte </div> <div id="el85_off" data-id="85" data-set="Monocyte52" data-type="No Products Click" class="dc_development_all pw-label el-off85" style="top:314.66668701171875px;left:386px;"> Monocyte</div> <div id="el85_ct" class="pw-tooltip" data-id="85"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/ccr2">CCR2-/+</a><br><a target="_blank" href="/target/ccr5">CCR5-/+</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1-/+</a><br><a target="_blank" href="/target/cd14">CD14+</a><br><a target="_blank" href="/target/fc-gamma-riii-cd16">Fc gamma RIII/CD16-/+</a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br> </div> </div> <div id="el86_gry" class="dc_development_all pw-sprite el-gray86 pw-gray" style="top:314.66668701171875px;left:522.666748046875px;"> </div> <div id="el86_off" data-id="86" data-set="PlasmacytoidDendriticCellpDC-53" data-type="No Products Click" class="dc_development_all pw-sprite el-off86" style="top:314.66668701171875px;left:522.666748046875px;"> </div> <div id="el86_ct" class="pw-tooltip" data-id="86"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br>Lin-<br><a target="_blank" href="/target/cd1a">CD1a-</a><br><a target="_blank" href="/target/cd11c">CD11c<sup>low</sup></a><br><a target="_blank" href="/target/dlec-clec4c-bdca-2">DLEC/BDCA-2+</a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br><a target="_blank" href="/target/il-3-r-alpha-cd123">IL-3 R alpha/CD123+</a><br><a target="_blank" href="/target/neuropilin-1">Neuropilin-1/BDCA-4+</a><br><strong>Intracellular Markers</strong><br>E2-2/Tcf4+<br>IRF7+<br><a target="_blank" href="/target/irf8">IRF8+</a><br><a target="_blank" href="/target/spi-b">Spi-B+</a><br><a target="_blank" href="/target/tlr7">TLR7+</a><br><a target="_blank" href="/target/tlr9">TLR9+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/ifn-alpha">IFN-alpha</a><br><a target="_blank" href="/target/ifn-beta">IFN-beta</a><br><a target="_blank" href="/target/il-6">IL-6</a><br><a target="_blank" href="/target/tnf-alpha">TNF-alpha</a><br> </div> </div> <div id="el87_gry" class="dc_development_all pw-label pw-center el-gray87 pw-gray" style="top:336px;left:450px;"> Plasmacytoid<br>Dendritic Cell<br>(pDC) </div> <div id="el87_off" data-id="87" data-set="PlasmacytoidDendriticCellpDC-53" data-type="No Products Click" class="dc_development_all pw-label pw-center el-off87" style="top:336px;left:450px;"> Plasmacytoid<br>Dendritic Cell<br>(pDC)</div> <div id="el87_ct" class="pw-tooltip" data-id="87"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br>Lin-<br><a target="_blank" href="/target/cd1a">CD1a-</a><br><a target="_blank" href="/target/cd11c">CD11c<sup>low</sup></a><br><a target="_blank" href="/target/dlec-clec4c-bdca-2">DLEC/BDCA-2+</a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br><a target="_blank" href="/target/il-3-r-alpha-cd123">IL-3 R alpha/CD123+</a><br><a target="_blank" href="/target/neuropilin-1">Neuropilin-1/BDCA-4+</a><br><strong>Intracellular Markers</strong><br>E2-2/Tcf4+<br>IRF7+<br><a target="_blank" href="/target/irf8">IRF8+</a><br><a target="_blank" href="/target/spi-b">Spi-B+</a><br><a target="_blank" href="/target/tlr7">TLR7+</a><br><a target="_blank" href="/target/tlr9">TLR9+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/ifn-alpha">IFN-alpha</a><br><a target="_blank" href="/target/ifn-beta">IFN-beta</a><br><a target="_blank" href="/target/il-6">IL-6</a><br><a target="_blank" href="/target/tnf-alpha">TNF-alpha</a><br> </div> </div> <div id="el88_gry" class="dc_development_all pw-sprite el-gray88 pw-gray" style="top:294.66668701171875px;left:560.666748046875px;"> </div> <div id="el88_off" data-id="88" data-set="HumanEquivalentofPre-DC54" data-type="No Products Click" class="dc_development_all pw-sprite el-off88" style="top:294.66668701171875px;left:560.666748046875px;"> </div> <div id="el88_ct" class="pw-tooltip" data-id="88"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1-</a><br><a target="_blank" href="/target/cd34">CD34-</a><br>CD45RA+<br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit+</a><br><a target="_blank" href="/target/thrombomodulin-bdca-3">CD141/BDCA-3-</a><br><a target="_blank" href="/target/dlec-clec4c-bdca-2">DLEC/BDCA-2-</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br><a target="_blank" href="/target/gm-csf-r-alpha">GM-CSF R+</a><br><a target="_blank" href="/target/il-3-r-alpha-cd123">IL-3 R alpha/CD123<sup>-/low</sup></a><br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115-</a><br> </div> </div> <div id="el89_gry" class="dc_development_all pw-label el-gray89 pw-gray" style="top:294.66668701171875px;left:602px;"> Human Equivalent of Pre-DC </div> <div id="el89_off" data-id="89" data-set="HumanEquivalentofPre-DC54" data-type="No Products Click" class="dc_development_all pw-label el-off89" style="top:294.66668701171875px;left:602px;"> Human Equivalent of Pre-DC</div> <div id="el89_ct" class="pw-tooltip" data-id="89"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1-</a><br><a target="_blank" href="/target/cd34">CD34-</a><br>CD45RA+<br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit+</a><br><a target="_blank" href="/target/thrombomodulin-bdca-3">CD141/BDCA-3-</a><br><a target="_blank" href="/target/dlec-clec4c-bdca-2">DLEC/BDCA-2-</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br><a target="_blank" href="/target/gm-csf-r-alpha">GM-CSF R+</a><br><a target="_blank" href="/target/il-3-r-alpha-cd123">IL-3 R alpha/CD123<sup>-/low</sup></a><br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115-</a><br> </div> </div> <div id="el90_gry" class="dc_development_all pw-sprite el-gray90 pw-gray" style="top:476.66668701171875px;left:388.666748046875px;"> </div> <div id="el90_off" data-id="90" data-set="BloodMonocyte55" data-type="No Products Click" class="dc_development_all pw-sprite el-off90" style="top:476.66668701171875px;left:388.666748046875px;"> </div> <div id="el90_ct" class="pw-tooltip" data-id="90"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/ccr2">CCR2-/+</a><br><a target="_blank" href="/target/ccr5">CCR5-/+</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1-/+</a><br><a target="_blank" href="/target/cd14">CD14+</a><br><a target="_blank" href="/target/fc-gamma-riii-cd16">Fc gamma RIII/CD16-/+</a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br> </div> </div> <div id="el91_gry" class="dc_development_all pw-label pw-center el-gray91 pw-gray" style="top:508px;left:369px;"> Blood<br>Monocyte </div> <div id="el91_off" data-id="91" data-set="BloodMonocyte55" data-type="No Products Click" class="dc_development_all pw-label pw-center el-off91" style="top:508px;left:369px;"> Blood<br>Monocyte</div> <div id="el91_ct" class="pw-tooltip" data-id="91"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/ccr2">CCR2-/+</a><br><a target="_blank" href="/target/ccr5">CCR5-/+</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1-/+</a><br><a target="_blank" href="/target/cd14">CD14+</a><br><a target="_blank" href="/target/fc-gamma-riii-cd16">Fc gamma RIII/CD16-/+</a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br> </div> </div> <div id="el92_gry" class="dc_development_all pw-sprite el-gray92 pw-gray" style="top:462.66668701171875px;left:438.666748046875px;"> </div> <div id="el92_off" data-id="92" data-set="pDC56" data-type="No Products Click" class="dc_development_all pw-sprite el-off92" style="top:462.66668701171875px;left:438.666748046875px;"> </div> <div id="el92_ct" class="pw-tooltip" data-id="92"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br>Lin-<br><a target="_blank" href="/target/cd1a">CD1a-</a><br><a target="_blank" href="/target/cd11c">CD11c<sup>low</sup></a><br><a target="_blank" href="/target/dlec-clec4c-bdca-2">DLEC/BDCA-2+</a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br><a target="_blank" href="/target/il-3-r-alpha-cd123">IL-3 R alpha/CD123+</a><br><a target="_blank" href="/target/neuropilin-1">Neuropilin-1/BDCA-4+</a><br><strong>Intracellular Markers</strong><br>E2-2/Tcf4+<br>IRF7+<br><a target="_blank" href="/target/irf8">IRF8+</a><br><a target="_blank" href="/target/spi-b">Spi-B+</a><br><a target="_blank" href="/target/tlr7">TLR7+</a><br><a target="_blank" href="/target/tlr9">TLR9+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/ifn-alpha">IFN-alpha</a><br><a target="_blank" href="/target/ifn-beta">IFN-beta</a><br><a target="_blank" href="/target/il-6">IL-6</a><br><a target="_blank" href="/target/tnf-alpha">TNF-alpha</a><br> </div> </div> <div id="el93_gry" class="dc_development_all pw-label el-gray93 pw-gray" style="top:491px;left:448px;"> pDC </div> <div id="el93_off" data-id="93" data-set="pDC56" data-type="No Products Click" class="dc_development_all pw-label el-off93" style="top:491px;left:448px;"> pDC</div> <div id="el93_ct" class="pw-tooltip" data-id="93"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br>Lin-<br><a target="_blank" href="/target/cd1a">CD1a-</a><br><a target="_blank" href="/target/cd11c">CD11c<sup>low</sup></a><br><a target="_blank" href="/target/dlec-clec4c-bdca-2">DLEC/BDCA-2+</a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br><a target="_blank" href="/target/il-3-r-alpha-cd123">IL-3 R alpha/CD123+</a><br><a target="_blank" href="/target/neuropilin-1">Neuropilin-1/BDCA-4+</a><br><strong>Intracellular Markers</strong><br>E2-2/Tcf4+<br>IRF7+<br><a target="_blank" href="/target/irf8">IRF8+</a><br><a target="_blank" href="/target/spi-b">Spi-B+</a><br><a target="_blank" href="/target/tlr7">TLR7+</a><br><a target="_blank" href="/target/tlr9">TLR9+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/ifn-alpha">IFN-alpha</a><br><a target="_blank" href="/target/ifn-beta">IFN-beta</a><br><a target="_blank" href="/target/il-6">IL-6</a><br><a target="_blank" href="/target/tnf-alpha">TNF-alpha</a><br> </div> </div> <div id="el94_gry" class="dc_development_all pw-label2 el-gray94 pw-gray" style="top:428.66668701171875px;left:552px;"> Blood DCs </div> <div id="el94_off" data-id="94" data-set="BloodDCs" data-type="" class="dc_development_all pw-label2 el-off94" style="top:428.66668701171875px;left:552px;"> Blood DCs</div> <div id="el94_ct" class="pw-tooltip" data-id="94"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el95_gry" class="dc_development_all pw-sprite el-gray95 pw-gray" style="top:420.66668701171875px;left:506.666748046875px;"> </div> <div id="el95_off" data-id="95" data-set="CD141BDCA-3cDC58" data-type="" class="dc_development_all pw-sprite el-off95" style="top:420.66668701171875px;left:506.666748046875px;"> </div> <div id="el95_ct" class="pw-tooltip" data-id="95"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br>Lin-<br><a target="_blank" href="/target/cd1a">CD1a-</a><br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1-</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M<sup>low</sup></a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/thrombomodulin-bdca-3">CD141/BDCA-3+</a><br><a target="_blank" href="/target/clec9a">CLEC9a+</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1-</a><br><a target="_blank" href="/target/dec-205-cd205">DEC-205/CD205<sup>high</sup></a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br><a target="_blank" href="/target/igsf4a-syncam1">IGSF4a/SynCAM1/Necl2+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a-</a><br><a target="_blank" href="/target/xcr1">XCR1+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/il-12">IL-12</a><br> </div> </div> <div id="el96_gry" class="dc_development_all pw-label pw-center el-gray96 pw-gray" style="top:464px;left:484px;"> CD141/BDCA-3<sup>+</sup><br>cDC </div> <div id="el96_off" data-id="96" data-set="CD141BDCA-3cDC58" data-type="No Products Click" class="dc_development_all pw-label pw-center el-off96" style="top:464px;left:484px;"> CD141/BDCA-3<sup>+</sup><br>cDC</div> <div id="el96_ct" class="pw-tooltip" data-id="96"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br>Lin-<br><a target="_blank" href="/target/cd1a">CD1a-</a><br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1-</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M<sup>low</sup></a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/thrombomodulin-bdca-3">CD141/BDCA-3+</a><br><a target="_blank" href="/target/clec9a">CLEC9a+</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1-</a><br><a target="_blank" href="/target/dec-205-cd205">DEC-205/CD205<sup>high</sup></a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br><a target="_blank" href="/target/igsf4a-syncam1">IGSF4a/SynCAM1/Necl2+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a-</a><br><a target="_blank" href="/target/xcr1">XCR1+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/il-12">IL-12</a><br> </div> </div> <div id="el97_gry" class="dc_development_all pw-sprite el-gray97 pw-gray" style="top:404.66668701171875px;left:612.666748046875px;"> </div> <div id="el97_off" data-id="97" data-set="CD1cBDCA-1cDC59" data-type="No Products Click" class="dc_development_all pw-sprite el-off97" style="top:404.66668701171875px;left:612.666748046875px;"> </div> <div id="el97_ct" class="pw-tooltip" data-id="97"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br>Lin-<br><a target="_blank" href="/target/cd1a">CD1a-</a><br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M<sup>low</sup></a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/thrombomodulin-bdca-3">CD141/BDCA-3+/-</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1+</a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/il-1-beta-il-1f2">IL-1 beta</a><br><a target="_blank" href="/target/il-6">IL-6</a><br><a target="_blank" href="/target/il-10">IL-10</a><br><a target="_blank" href="/target/il-12">IL-12</a><br><a target="_blank" href="/target/tnf-alpha">TNF-alpha</a><br> </div> </div> <div id="el98_gry" class="dc_development_all pw-label pw-center el-gray98 pw-gray" style="top:444px;left:591px;"> CD1c/BDCA-1<sup>+</sup><br>cDC </div> <div id="el98_off" data-id="98" data-set="CD1cBDCA-1cDC59" data-type="No Products Click" class="dc_development_all pw-label pw-center el-off98" style="top:444px;left:591px;"> CD1c/BDCA-1<sup>+</sup><br>cDC</div> <div id="el98_ct" class="pw-tooltip" data-id="98"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br>Lin-<br><a target="_blank" href="/target/cd1a">CD1a-</a><br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M<sup>low</sup></a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/thrombomodulin-bdca-3">CD141/BDCA-3+/-</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1+</a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/il-1-beta-il-1f2">IL-1 beta</a><br><a target="_blank" href="/target/il-6">IL-6</a><br><a target="_blank" href="/target/il-10">IL-10</a><br><a target="_blank" href="/target/il-12">IL-12</a><br><a target="_blank" href="/target/tnf-alpha">TNF-alpha</a><br> </div> </div> <div id="el99_gry" class="dc_development_all pw-sprite el-gray99 pw-gray" style="top:402.66668701171875px;left:668.666748046875px;"> </div> <div id="el99_off" data-id="99" data-set="Pre-DC60" data-type="No Products Click" class="dc_development_all pw-sprite el-off99" style="top:402.66668701171875px;left:668.666748046875px;"> </div> <div id="el99_ct" class="pw-tooltip" data-id="99"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1-</a><br><a target="_blank" href="/target/cd34">CD34-</a><br>CD45RA+<br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit+</a><br><a target="_blank" href="/target/thrombomodulin-bdca-3">CD141/BDCA-3-</a><br><a target="_blank" href="/target/dlec-clec4c-bdca-2">DLEC/BDCA-2-</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br><a target="_blank" href="/target/gm-csf-r-alpha">GM-CSF R+</a><br><a target="_blank" href="/target/il-3-r-alpha-cd123">IL-3 R alpha/CD123<sup>-/low</sup></a><br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115-</a><br> </div> </div> <div id="el100_gry" class="dc_development_all pw-label el-gray100 pw-gray" style="top:400px;left:704px;"> Pre-DC </div> <div id="el100_off" data-id="100" data-set="Pre-DC60" data-type="No Products Click" class="dc_development_all pw-label el-off100" style="top:400px;left:704px;"> Pre-DC</div> <div id="el100_ct" class="pw-tooltip" data-id="100"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1-</a><br><a target="_blank" href="/target/cd34">CD34-</a><br>CD45RA+<br><a target="_blank" href="/target/cd117-c-kit">CD117/c-kit+</a><br><a target="_blank" href="/target/thrombomodulin-bdca-3">CD141/BDCA-3-</a><br><a target="_blank" href="/target/dlec-clec4c-bdca-2">DLEC/BDCA-2-</a><br><a target="_blank" href="/target/flt-3-flk-2">Flt-3/Flk-2+</a><br><a target="_blank" href="/target/gm-csf-r-alpha">GM-CSF R+</a><br><a target="_blank" href="/target/il-3-r-alpha-cd123">IL-3 R alpha/CD123<sup>-/low</sup></a><br><a target="_blank" href="/target/m-csf-r-cd115">M-CSF R/CD115-</a><br> </div> </div> <div id="el101_gry" class="dc_development_all pw-label2 pw-center el-gray101 pw-gray" style="top:598px;left:389px;"> Peripheral Tissues &<br>Draining Lymph Nodes<br>During Inflammation </div> <div id="el101_off" data-id="101" data-set="PeripheralTissuesDrainingLymphNodesDuringInflammation" data-type="" class="dc_development_all pw-label2 pw-center el-off101" style="top:598px;left:389px;"> Peripheral Tissues &<br>Draining Lymph Nodes<br>During Inflammation</div> <div id="el101_ct" class="pw-tooltip" data-id="101"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el102_gry" class="dc_development_all pw-sprite el-gray102 pw-gray" style="top:646.6666870117188px;left:438.666748046875px;"> </div> <div id="el102_off" data-id="102" data-set="HumanInflammatoryMonocyte-derivedDC62" data-type="" class="dc_development_all pw-sprite el-off102" style="top:646.6666870117188px;left:438.666748046875px;"> </div> <div id="el102_ct" class="pw-tooltip" data-id="102"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br>Lin-<br><a target="_blank" href="/target/cd1a">CD1a+</a><br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+/-</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd14">CD14+</a><br><a target="_blank" href="/target/fc-gamma-ri-cd64">Fc gamma RI/CD64+</a><br><a target="_blank" href="/target/fc-epsilon-ri-alpha">Fc epsilon RI+</a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br><a target="_blank" href="/target/mmr-cd206">MMR/CD206+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/il-23">IL-23</a><br><a target="_blank" href="/target/nitric-oxide">NO</a><br><a target="_blank" href="/target/tnf-alpha">TNF-alpha</a><br> </div> </div> <div id="el103_gry" class="dc_development_all pw-label pw-center el-gray103 pw-gray" style="top:688px;left:423px;"> Human<br>Inflammatory<br>Monocyte-<br>derived DC </div> <div id="el103_off" data-id="103" data-set="HumanInflammatoryMonocyte-derivedDC62" data-type="No Products Click" class="dc_development_all pw-label pw-center el-off103" style="top:688px;left:423px;"> Human<br>Inflammatory<br>Monocyte-<br>derived DC</div> <div id="el103_ct" class="pw-tooltip" data-id="103"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br>Lin-<br><a target="_blank" href="/target/cd1a">CD1a+</a><br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+/-</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd14">CD14+</a><br><a target="_blank" href="/target/fc-gamma-ri-cd64">Fc gamma RI/CD64+</a><br><a target="_blank" href="/target/fc-epsilon-ri-alpha">Fc epsilon RI+</a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br><a target="_blank" href="/target/mmr-cd206">MMR/CD206+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/il-23">IL-23</a><br><a target="_blank" href="/target/nitric-oxide">NO</a><br><a target="_blank" href="/target/tnf-alpha">TNF-alpha</a><br> </div> </div> <div id="el104_gry" class="dc_development_all pw-label2 el-gray104 pw-gray" style="top:498.66668701171875px;left:618px;"> Human Skin </div> <div id="el104_off" data-id="104" data-set="HumanSkin" data-type="" class="dc_development_all pw-label2 el-off104" style="top:498.66668701171875px;left:618px;"> Human Skin </div> <div id="el104_ct" class="pw-tooltip" data-id="104"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el105_gry" class="dc_development_all pw-label2 el-gray105 pw-gray" style="top:603px;left:598px;"> CD1a<sup>+</sup> Dermal DCs </div> <div id="el105_off" data-id="105" data-set="CD1aDermalDCs" data-type="" class="dc_development_all pw-label2 el-off105" style="top:603px;left:598px;"> CD1a<sup>+</sup> Dermal DCs</div> <div id="el105_ct" class="pw-tooltip" data-id="105"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el106_gry" class="dc_development_all pw-sprite el-gray106 pw-gray" style="top:522.6666870117188px;left:596.666748046875px;"> </div> <div id="el106_off" data-id="106" data-set="CD1cDermalDC65" data-type="" class="dc_development_all pw-sprite el-off106" style="top:522.6666870117188px;left:596.666748046875px;"> </div> <div id="el106_ct" class="pw-tooltip" data-id="106"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd1a">CD1a+</a><br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M<sup>high</sup></a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd14">CD14-</a><br><a target="_blank" href="/target/thrombomodulin-bdca-3">CD141/BDCA-3<sup>-/low</sup></a><br><a target="_blank" href="/target/cd163">CD163-</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209-</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1-</a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207-</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a+</a><br> </div> </div> <div id="el107_gry" class="dc_development_all pw-label pw-center el-gray107 pw-gray" style="top:565px;left:585px;"> CD1c<sup>+</sup><br>Dermal DC </div> <div id="el107_off" data-id="107" data-set="CD1cDermalDC65" data-type="No Products Click" class="dc_development_all pw-label pw-center el-off107" style="top:565px;left:585px;"> CD1c<sup>+</sup><br>Dermal DC</div> <div id="el107_ct" class="pw-tooltip" data-id="107"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd1a">CD1a+</a><br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M<sup>high</sup></a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd14">CD14-</a><br><a target="_blank" href="/target/thrombomodulin-bdca-3">CD141/BDCA-3<sup>-/low</sup></a><br><a target="_blank" href="/target/cd163">CD163-</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209-</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1-</a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207-</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a+</a><br> </div> </div> <div id="el108_gry" class="dc_development_all pw-sprite el-gray108 pw-gray" style="top:522.6666870117188px;left:658.666748046875px;"> </div> <div id="el108_off" data-id="108" data-set="CD141DermalDC66" data-type="No Products Click" class="dc_development_all pw-sprite el-off108" style="top:522.6666870117188px;left:658.666748046875px;"> </div> <div id="el108_ct" class="pw-tooltip" data-id="108"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd1a">CD1a+</a><br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1<sup>low/int</sup></a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M<sup>high</sup></a><br><a target="_blank" href="/target/cd11c">CD11c<sup>low</sup></a><br><a target="_blank" href="/target/cd14">CD14-</a><br><a target="_blank" href="/target/thrombomodulin-bdca-3">CD141/BDCA-3+</a><br><a target="_blank" href="/target/cd163">CD163-</a><br><a target="_blank" href="/target/clec9a">CLEC9a+</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209-</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1-</a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br><a target="_blank" href="/target/igsf4a-syncam1">IGSF4A/SynCAM1/Necl2+</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207-</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a+</a><br><a target="_blank" href="/target/xcr1">XCR1+</a><br> </div> </div> <div id="el109_gry" class="dc_development_all pw-label pw-center el-gray109 pw-gray" style="top:565px;left:660px;"> CD141<sup>+</sup><br>Dermal DC </div> <div id="el109_off" data-id="109" data-set="CD141DermalDC66" data-type="No Products Click" class="dc_development_all pw-label pw-center el-off109" style="top:565px;left:660px;"> CD141<sup>+</sup><br>Dermal DC</div> <div id="el109_ct" class="pw-tooltip" data-id="109"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd1a">CD1a+</a><br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1<sup>low/int</sup></a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M<sup>high</sup></a><br><a target="_blank" href="/target/cd11c">CD11c<sup>low</sup></a><br><a target="_blank" href="/target/cd14">CD14-</a><br><a target="_blank" href="/target/thrombomodulin-bdca-3">CD141/BDCA-3+</a><br><a target="_blank" href="/target/cd163">CD163-</a><br><a target="_blank" href="/target/clec9a">CLEC9a+</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209-</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1-</a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br><a target="_blank" href="/target/igsf4a-syncam1">IGSF4A/SynCAM1/Necl2+</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207-</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a+</a><br><a target="_blank" href="/target/xcr1">XCR1+</a><br> </div> </div> <div id="el110_gry" class="dc_development_all pw-sprite el-gray110 pw-gray" style="top:658.6666870117188px;left:616.666748046875px;"> </div> <div id="el110_off" data-id="110" data-set="CD14DermalDC67" data-type="No Products Click" class="dc_development_all pw-sprite el-off110" style="top:658.6666870117188px;left:616.666748046875px;"> </div> <div id="el110_ct" class="pw-tooltip" data-id="110"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd1a">CD1a-</a><br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1+/-</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd14">CD14+</a><br><a target="_blank" href="/target/cd163">CD163-/+</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209+</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1-</a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207-</a><br> </div> </div> <div id="el111_gry" class="dc_development_all pw-label pw-center el-gray111 pw-gray" style="top:636px;left:582px;"> CD14<sup>+</sup><br>Dermal DC </div> <div id="el111_off" data-id="111" data-set="CD14DermalDC67" data-type="No Products Click" class="dc_development_all pw-label pw-center el-off111" style="top:636px;left:582px;"> CD14<sup>+</sup><br>Dermal DC</div> <div id="el111_ct" class="pw-tooltip" data-id="111"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd1a">CD1a-</a><br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1+/-</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd14">CD14+</a><br><a target="_blank" href="/target/cd163">CD163-/+</a><br><a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209+</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1-</a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207-</a><br> </div> </div> <div id="el112_gry" class="dc_development_all pw-sprite el-gray112 pw-gray" style="top:636.6666870117188px;left:668.666748046875px;"> </div> <div id="el112_off" data-id="112" data-set="LangerhansCell68" data-type="No Products Click" class="dc_development_all pw-sprite el-off112" style="top:636.6666870117188px;left:668.666748046875px;"> </div> <div id="el112_ct" class="pw-tooltip" data-id="112"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd1a">CD1a+</a><br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+/-</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd14">CD14-</a><br><a target="_blank" href="/target/e-cadherin">E-Cadherin+</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1+</a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a+</a><br> </div> </div> <div id="el113_gry" class="dc_development_all pw-label el-gray113 pw-gray" style="top:628.6666870117188px;left:644px;"> Langerhans Cell </div> <div id="el113_off" data-id="113" data-set="LangerhansCell68" data-type="No Products Click" class="dc_development_all pw-label el-off113" style="top:628.6666870117188px;left:644px;"> Langerhans Cell</div> <div id="el113_ct" class="pw-tooltip" data-id="113"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> Lin-<br><a target="_blank" href="/target/cd1a">CD1a+</a><br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M+/-</a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/cd14">CD14-</a><br><a target="_blank" href="/target/e-cadherin">E-Cadherin+</a><br><a target="_blank" href="/target/epcam-trop1">EpCAM/TROP1+</a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br><a target="_blank" href="/target/langerin-cd207">Langerin/CD207+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a+</a><br> </div> </div> <div id="el114_gry" class="dc_development_all pw-label2 pw-center el-gray114 pw-gray" style="top:773px;left:503px;"> Human Secondary Lymphoid Organs/Non-lymphoid Tissue Parenchyma </div> <div id="el114_off" data-id="114" data-set="HumanSecondaryLymphoidOrgansNon-lymphoidTissueParenchyma" data-type="" class="dc_development_all pw-label2 pw-center el-off114" style="top:773px;left:503px;"> Human Secondary Lymphoid Organs/Non-lymphoid Tissue Parenchyma</div> <div id="el114_ct" class="pw-tooltip" data-id="114"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el115_gry" class="dc_development_all pw-sprite el-gray115 pw-gray" style="top:826.6666870117188px;left:614.666748046875px;"> </div> <div id="el115_off" data-id="115" data-set="pDC70" data-type="" class="dc_development_all pw-sprite el-off115" style="top:826.6666870117188px;left:614.666748046875px;"> </div> <div id="el115_ct" class="pw-tooltip" data-id="115"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br>Lin-<br><a target="_blank" href="/target/cd1a">CD1a-</a><br><a target="_blank" href="/target/cd11c">CD11c<sup>low</sup><br><a target="_blank" href="/target/dlec-clec4c-bdca-2">DLEC/BDCA-2+</a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br><a target="_blank" href="/target/il-3-r-alpha-cd123">IL-3 R alpha/CD123+</a><br><a target="_blank" href="/target/neuropilin-1">Neuropilin-1/BDCA-4+</a><br><strong>Intracellular Markers</strong><br>E2-2/Tcf4+<br>IRF7+<br><a target="_blank" href="/target/irf8">IRF8+</a><br><a target="_blank" href="/target/spi-b">Spi-B+</a><br><a target="_blank" href="/target/tlr7">TLR7+</a><br><a target="_blank" href="/target/tlr9">TLR9+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/ifn-alpha">IFN-alpha</a><br><a target="_blank" href="/target/ifn-beta">IFN-beta</a><br><a target="_blank" href="/target/il-6">IL-6</a><br><a target="_blank" href="/target/tnf-alpha">TNF-alpha</a><br> </div> </div> <div id="el116_gry" class="dc_development_all pw-label el-gray116 pw-gray" style="top:836.6666870117188px;left:588px;"> pDC </div> <div id="el116_off" data-id="116" data-set="pDC70" data-type="No Products Click" class="dc_development_all pw-label el-off116" style="top:836.6666870117188px;left:588px;"> pDC</div> <div id="el116_ct" class="pw-tooltip" data-id="116"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br>Lin-<br><a target="_blank" href="/target/cd1a">CD1a-</a><br><a target="_blank" href="/target/cd11c">CD11c<sup>low</sup></a><br><a target="_blank" href="/target/dlec-clec4c-bdca-2">DLEC/BDCA-2+</a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br><a target="_blank" href="/target/il-3-r-alpha-cd123">IL-3 R alpha/CD123+</a><br><a target="_blank" href="/target/neuropilin-1">Neuropilin-1/BDCA-4+</a><br><strong>Intracellular Markers</strong><br>E2-2/Tcf4+<br>IRF7+<br><a target="_blank" href="/target/irf8">IRF8+</a><br><a target="_blank" href="/target/spi-b">Spi-B+</a><br><a target="_blank" href="/target/tlr7">TLR7+</a><br><a target="_blank" href="/target/tlr9">TLR9+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/ifn-alpha">IFN-alpha</a><br><a target="_blank" href="/target/ifn-beta">IFN-beta</a><br><a target="_blank" href="/target/il-6">IL-6</a><br><a target="_blank" href="/target/tnf-alpha">TNF-alpha</a><br> </div> </div> <div id="el117_gry" class="dc_development_all pw-sprite el-gray117 pw-gray" style="top:862.6666870117188px;left:548px;"> </div> <div id="el117_off" data-id="117" data-set="CD141BDCA-3cDC71" data-type="No Products Click" class="dc_development_all pw-sprite el-off117" style="top:862.6666870117188px;left:548px;"> </div> <div id="el117_ct" class="pw-tooltip" data-id="117"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br>Lin-<br><a target="_blank" href="/target/cd1a">CD1a-</a><br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1-</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M<sup>low</sup></a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/thrombomodulin-bdca-3">CD141/BDCA-3+</a><br><a target="_blank" href="/target/clec9a">CLEC9a+</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1-</a><br><a target="_blank" href="/target/dec-205-cd205">DEC-205/CD205<sup>high</sup></a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br><a target="_blank" href="/target/igsf4a-syncam1">IGSF4a/SynCAM1/Necl2+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a-</a><br><a target="_blank" href="/target/xcr1">XCR1+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/il-12">IL-12</a><br> </div> </div> <div id="el118_gry" class="dc_development_all pw-label pw-center el-gray118 pw-gray" style="top:872px;left:600px;"> CD141/BDCA-3<sup>+</sup><br>cDC </div> <div id="el118_off" data-id="118" data-set="CD141BDCA-3cDC71" data-type="No Products Click" class="dc_development_all pw-label pw-center el-off118" style="top:872px;left:600px;"> CD141/BDCA-3<sup>+</sup><br>cDC</div> <div id="el118_ct" class="pw-tooltip" data-id="118"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br>Lin-<br><a target="_blank" href="/target/cd1a">CD1a-</a><br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1-</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M<sup>low</sup></a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/thrombomodulin-bdca-3">CD141/BDCA-3+</a><br><a target="_blank" href="/target/clec9a">CLEC9a+</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1-</a><br><a target="_blank" href="/target/dec-205-cd205">DEC-205/CD205<sup>high</sup></a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br><a target="_blank" href="/target/igsf4a-syncam1">IGSF4a/SynCAM1/Necl2+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a-</a><br><a target="_blank" href="/target/xcr1">XCR1+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/il-12">IL-12</a><br> </div> </div> <div id="el119_gry" class="dc_development_all pw-sprite el-gray119 pw-gray" style="top:912.6666870117188px;left:636.666748046875px;"> </div> <div id="el119_off" data-id="119" data-set="CD1cBDCA-1cDC72" data-type="No Products Click" class="dc_development_all pw-sprite el-off119" style="top:912.6666870117188px;left:636.666748046875px;"> </div> <div id="el119_ct" class="pw-tooltip" data-id="119"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br>Lin-<br><a target="_blank" href="/target/cd1a">CD1a-</a><br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M<sup>low</sup></a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/thrombomodulin-bdca-3">CD141/BDCA-3+/-</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1+</a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/il-1-beta-il-1f2">IL-1 beta</a><br><a target="_blank" href="/target/il-6">IL-6</a><br><a target="_blank" href="/target/il-10">IL-10</a><br><a target="_blank" href="/target/il-12">IL-12</a><br><a target="_blank" href="/target/tnf-alpha">TNF-alpha</a><br> </div> </div> <div id="el120_gry" class="dc_development_all pw-label pw-center el-gray120 pw-gray" style="top:924px;left:554px;"> CD1c/BDCA-1<sup>+</sup><br>cDC </div> <div id="el120_off" data-id="120" data-set="CD1cBDCA-1cDC72" data-type="No Products Click" class="dc_development_all pw-label pw-center el-off120" style="top:924px;left:554px;"> CD1c/BDCA-1<sup>+</sup><br>cDC</div> <div id="el120_ct" class="pw-tooltip" data-id="120"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <strong>Cell Surface Markers</strong><br>Lin-<br><a target="_blank" href="/target/cd1a">CD1a-</a><br><a target="_blank" href="/target/cd1c-bdca-1">CD1c/BDCA-1+</a><br><a target="_blank" href="/target/cd11b-integrin-alpha-m">CD11b/Integrin alpha M<sup>low</sup></a><br><a target="_blank" href="/target/cd11c">CD11c+</a><br><a target="_blank" href="/target/thrombomodulin-bdca-3">CD141/BDCA-3+/-</a><br><a target="_blank" href="/target/cx3cr1">CX3CR1+</a><br><a target="_blank" href="/target/hla-dr">HLA-DR+</a><br><a target="_blank" href="/target/sirp-alpha-cd172a">SIRP alpha/CD172a+</a><br><strong>Secreted Molecules</strong><br><a target="_blank" href="/target/il-1-beta-il-1f2">IL-1 beta</a><br><a target="_blank" href="/target/il-6">IL-6</a><br><a target="_blank" href="/target/il-10">IL-10</a><br><a target="_blank" href="/target/il-12">IL-12</a><br><a target="_blank" href="/target/tnf-alpha">TNF-alpha</a><br> </div> </div> </div> <div id="pw-img"> <img id="cont-img" src="https://resources.rndsystems.com/images/Pathways/pathway-images/dc-bkgd.png?t=6" alt="Dendritic Cell Lineage Development Pathways" style="height:1451px"> </div> </div> <div id="pathway-description"><p><div class="row"> <div class="col-md-4 col-xs-12"> <div class="featured-box"> <h2>Featured Literature</h2> <img src="//resources.rndsystems.com/images/site/pathway-resource-human-mouse-dc-subset-tn.jpg" alt="Dendritic Cells Brochure" width="100%"> <h3>Mouse and Human Dendritic Cell Subsets Poster</h3> <a href="/resources/posters/mouse-human-dendritic-cell-subsets" class="btn btn-senary" target="_blank">View Poster</a> </div> </div> <div class="col-md-4 col-xs-12"> <div class="featured-box"> <h2>Featured Products</h2> <img src="//resources.rndsystems.com/images/site/pathway-resource-dendritic-brochure.jpg" alt="Dendritic Cells Brochure" width="100%"> <h3>Dendritic Cells Brochure</h3> <a href="/resources/literature/dendritic-cell-development-and-subset-identification" class="btn btn-senary" target="_blank">View Brochure</a> </div> </div> <div style="clear:both"> </div> </div> <h2>Overview of Dendritic Cell Lineage Development</h2> <style type="text/css"> .container_16 {padding:0px !important;} .main.grid_16, .grid_16.base_rnd_css {width:1170px !important;} #pw-nav-con { width: 750px; height: inherit !important; background: none; } #pw-nav-con H2 { margin: 7px 0 5px 16px; padding: 5px 0; font-size: 19px; font-weight: inherit; width: 730px; border: none; } #pw-nav-con ul { margin: 0; padding: 0; height: 40px; } .pw-blu-btn { width: inherit; float: left; margin-left: 15px;} #pw-nav-con .pw-blu-btn a { background: #005F9E; border-top: 1px solid #005f9f;} #pw-nav-con .pw-blu-btn-active { border-top: none;} #pw-nav-con .pw-drk-blu-btn, #pw-nav-con li a /*request print button*/ { display: initial; padding: 5px 10px; font-weight: bold; background: #ffffff; border: 1px solid #005f9f; color: #090909; border-radius: 4px;} #pw-nav-con .pw-blu-btn-active { margin-left: 15px; float: left;} .related-information { background: #efefef; border: 1px solid #cccccc; position: relative; top: -54px;} .featured-links { display: block; text-decoration: none;} </style> <p>Dendritic cells (DCs) are key mediators of the innate and adaptive immune responses due to their abilities to: 1) upregulate MHC molecules and costimulatory receptors upon pathogen recognition, 2) capture, process, and present antigens to naïve T cells, and 3) produce polarizing cytokines that promote pathogen-specific effector T cell differentiation and activation. In addition, DCs can promote self-tolerance by secreting tolerogenic cytokines that induce the differentiation of regulatory T cells.</p> <p>With the exception of Langerhans cells which develop from precursor cells in the yolk sac and fetal liver, dendritic cells in mice develop from macrophage-dendritic cell precursors (MDPs) in the bone marrow. MDPs give rise to common monocyte progenitors (cMoPs) and common DC progenitors (CDPs). cMoPs develop into blood monocytes, which migrate to inflamed tissues, where they differentiate into monocyte-derived dendritic cells (MoDCs). In contrast, CDPs give rise to plasmacytoid dendritic cells (pDCs) and pre-DCs (cDC progenitors). pDCs fully mature in the bone marrow prior to entering the bloodstream, while pre-DCs migrate through the blood to lymphoid and non-lymphoid tissues, where they then differentiate into classical DC (cDC) subsets. Dendritic cell development in humans is not as clearly established but both granulocyte-macrophage progenitors (GMPs) and multi-lymphoid progenitors (MLPs) have been suggested to have the potential to differentiate into a MDP- or CDP-like progenitor. These progenitors are thought to subsequently differentiate into cMoPs, pDCs, and the human equivalent of pre-DCs. Similar to what is seen in mice, human cMoPs develop into blood monocytes, which differentiate into MoDCs in inflamed tissues, and fully mature pDCs along with immature pre-DCs migrate through the blood to tissues. Immature human pre-DCs differentiate either in the bloodstream or in tissues following migration.</p> <p>Several mouse and human cDC subsets have been characterized based on the differential expression of specific cell surface and intracellular markers on DCs isolated from different tissues. In mouse lymphoid tissue, two cDC subsets have been characterized based on their expression of either CD8 alpha or CD11b. CD8 alpha<sup>+</sup> cDCs are specialized in their ability to cross-present antigens on MHC class I molecules to CD8<sup>+</sup> T cells and prime Th1 and cytotoxic T cell responses, while CD11b<sup>+</sup> cDCs preferentially interact with CD4<sup>+</sup> T cells through MHC class II-antigenic peptide complexes. In addition to the lymphoid tissue-resident mouse cDCs subsets, several tissue migratory/non-lymphoid tissue cDC subsets have also been characterized. In mouse skin, five different cDC subsets have been identified including Langerhans cells and four other dermal DC subtypes that are distinguished based on the expression or lack of expression of CD103, CD11b, and CD207. In mouse lung, liver, and kidney, two cDC subsets have been identified that are either CD103<sup>+</sup> CD11b<sup>-</sup> or CD103<sup>-</sup> CD11b<sup>+</sup>. Similarly, in mouse intestinal lamina propria and Peyer’s patches, both CD103<sup>+</sup> CD11b<sup>-</sup> and CD103<sup>-</sup> CD11b<sup>+</sup> cDCs have been found, along with a third subset that expresses both CD103 and CD11b.</p> <p>Significant differences between the markers expressed on mouse and human cDCs have hindered the characterization of cDC subsets in humans. To date, only two subsets of human cDCs have been identified in the blood, spleen, and tonsils based on the expression of either CD141/BDCA-3 or CD1c/BDCA-1. Human CD141/BDCA-3<sup>+</sup> cDCs are thought to be phenotypically and functionally similar to mouse CD8 alpha<sup>+</sup> cDCs, while human CD1c/BDCA-3<sup>+</sup> cDCs correspond to mouse CD11b<sup>+</sup> cDCs. In addition to these two human cDC subsets, four other DC subsets have been characterized in the human skin including Langerhans cells, CD1a<sup>+</sup> CD1c/BDCA-1<sup>+</sup>, CD1a<sup>+</sup> CD141/BDCA-3<sup>+</sup>, and CD1a<sup>-</sup> CD14<sup>+</sup> dermal DCs.</p> <p>Unlike cDCs where multiple subsets have been identified, only one type of pDC has been characterized in both mouse and human. pDCs are relatively rare and are morphologically and functionally distinct from cDCs. They fully mature in the bone marrow before entering the bloodstream, have a spherical morphology, and express low levels of MHC class II prior to activation. Once activated, pDCs secrete large amounts of type I interferons and pro-inflammatory cytokines, and upregulate MHC class II and T cell co-stimulatory molecule expression, allowing them to function as antigen-presenting cells.</p> <p>To learn more, please visit our <a href="https://www.rndsystems.com/research-area/dendritic-cell-development--subsets-and-lineage--specific-markers">Dendritic Cell Subsets and Lineage-specific Markers research topic page</a>.</p> </p></div> <div id="print-copy-form" class="accordion-wrapper"> <h3 class="builder-header builder-bead-type ui-accordion-header ui-helper-reset ui-state-default ui-corner-all ui-accordion-icons" data-toggle="collapse" data-target="#collapsePathwayRequest" aria-expanded="false" id="pathwayRequestAccordionHeader"> <span class="ui-accordion-header-icon" id="accordionArrow"></span> Get Print Copy of this Pathway </h3> <div class="collapse" id="collapsePathwayRequest"> <div id="pathwayRequestWebformWrapper"> <form 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