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Global health estimates: Leading causes of death

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Since 2000, the largest increase in deaths has been for this disease, rising by 2.7 million to 9.0 million deaths in 2021. </li><li>As a newly emerged cause of deaths, COVID-19 was directly responsible for 8.7 million deaths in 2021.</li><li>Lower respiratory infections remained the world&rsquo;s most deadly communicable disease other than COVID-19, ranked as the fifth leading cause of death in 2021, although the total number of deaths from lower respiratory infections has decreased.</li></ul><p>&nbsp;</p><p>&nbsp;</p><p>&nbsp;</p><p>&nbsp;</p><p>&nbsp;</p><p>&nbsp;</p><p>&nbsp;</p><div class="arrowed-link"><a href="https://cdn.who.int/media/docs/default-source/gho-documents/global-health-estimates/ghe2021_cod_methods.pdf?sfvrsn=dca346b7_1">WHO methods and data sources for country-level causes of death 2000-2021</a></div></div></div> </div> </div> </div> </div> <div id="PageContent_C039_Col01" class="sf_colsIn col-md-4" data-sf-element="Column 2" data-placeholder-label="Column 2"><div class="row" data-sf-element="Row"> <div id="PageContent_C049_Col00" class="sf_colsIn col-md-12" data-sf-element="Column 1" data-placeholder-label="Column 1"> <div class="section-heading"> <h2>More on the Global Health Estimates</h2> </div> <div class="sf-content-block content-block" > <div ><p><ol><li><a href="/data/gho/data/themes/mortality-and-global-health-estimates/ghe-life-expectancy-and-healthy-life-expectancy">Life expectancy and healthy life expectancy</a></li><li><strong>Leading causes of death</strong></li><li><a href="/data/gho/data/themes/mortality-and-global-health-estimates/global-health-estimates-leading-causes-of-dalys">Leading causes of DALYs</a></li></ol><p><strong><a href="/data/gho/data/themes/mortality-and-global-health-estimates">Back to the Global Health Estimates page</a></strong></p><p><strong>&nbsp;</strong></p></p></div> </div> </div> </div> </div> </div> <div class="row" data-sf-element="Row"> <div id="PageContent_C064_Col00" class="sf_colsIn col-md-12" data-sf-element="Column 1" data-placeholder-label="Column 1"> <!-- Author: Shady A.Rashwan Date: 15-07-2024 Unit: DEX Topic: New Graph GHE Top 10 --> <style> .ghe-top10-widget { --primary-color: #3498db; 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} .ghe-top10-widget #data-table th, .ghe-top10-widget #data-table td { border: 1px solid var(--border-color); padding: 12px; text-align: left; } .ghe-top10-widget #data-table th { background-color: var(--primary-color); color: white; } .ghe-top10-widget #data-table tr:nth-child(even) { background-color: #f8f9fa; } .ghe-top10-widget .legend { display: flex; justify-content: center; margin-top: 20px; } .ghe-top10-widget .legend-item { display: flex; align-items: center; margin: 0 10px; } .ghe-top10-widget .legend-color { width: 20px; height: 20px; margin-right: 5px; border-radius: 3px; } </style> <div class="ghe-top10-widget"> <div id="ghe-top10"> <h2>Top 10 Causes of <span id="chart-type">Death</span></h2> <div id="subtitle"></div> <div id="controls"> <div class="filter-labels"> <label for="country-select">Country</label> <label for="year-select">Year</label> <label for="sex-select">Sex</label> <label for="age-select">Age</label> </div> <div class="filter-controls"> <select id="country-select"></select> <select id="year-select"></select> <select id="sex-select"></select> <select id="age-select"></select> </div> <div class="button-controls"> <button id="toggle-chart">Toggle DEATHs/DALYs</button> <a id="odata-download" href="#" target="_blank">Download with OData API</a> </div> </div> <div id="chart-container"> <canvas id="myChart"></canvas> <div id="loading-indicator">Loading data...</div> </div> <div class="legend"> <div class="legend-item"> <div class="legend-color" style="background-color: #117a65;"></div> <span>Communicable</span> </div> <div class="legend-item"> <div class="legend-color" style="background-color: #2e86c1;"></div> <span>Non-communicable</span> </div> <div class="legend-item"> <div class="legend-color" style="background-color: #002C5F;"></div> <span>Injuries</span> </div> </div> <div id="data-container"> <h3>Underlying Data</h3> <table id="data-table"> <thead> <tr> <th>Cause</th> <th>Value</th> <th>Category</th> </tr> </thead> <tbody></tbody> </table> </div> </div> </div> <script src="https://cdn.jsdelivr.net/npm/chart.js"></script> <script src="https://cdn.jsdelivr.net/npm/chartjs-plugin-datalabels@2.0.0"></script> </div> </div> <div class="row" data-sf-element="Row"> <div id="PageContent_C058_Col00" class="sf_colsIn col-md-12" data-sf-element="Column 1" data-placeholder-label="Column 1"><div class="row" data-sf-element="Row"> <div id="PageContent_C028_Col00" class="sf_colsIn col-md-12" data-sf-element="Column 1" data-placeholder-label="Column 1"> <script type="text/javascript"> /* Author: Shady A.Rashwan Date: 15-07-2024 Unit: DEX Topic: New Graph GHE Top 10 */ document.addEventListener('DOMContentLoaded', function() { const GHETop10 = (function() { const colorMap = { 'Communicable': '#117a65', 'Non-communicable': '#2e86c1', 'Injuries': '#002C5F' }; const __xmart_odata_api = "https://xmart-api-public.who.int"; const __xmart = "DEX_CMS"; let state = { data: [], filters: { country: 'AFG', year: '2021', sex: 'MALE', ageGroup: 'TOTAL' }, mode: 'death', dropdownData: {} }; let chart; let cache = {}; function init() { console.log('Initializing GHETop10...'); fetchDropdownData().then(() => { createControls(); fetchData(); }).catch(error => { console.error('Error during initialization:', error); showError('Failed to initialize the visualization. Please try refreshing the page.'); }); const toggleButton = document.querySelector('.ghe-top10-widget #toggle-chart'); if (toggleButton) { toggleButton.addEventListener('click', toggleChartType); } else { console.error('Toggle button not found'); } } async function fetchDropdownData() { try { const endpoints = { countries: '/REFMART/REF_COUNTRY?&$orderby=NAME_SHORT_EN asc&$select=CODE_ISO_3,NAME_SHORT_EN&$filter=GEO_SMALL_POP_FLAG eq false and WHO_LEGAL_STATUS eq \'M\'', years: '/DEX_CMS/REF_YEAR_COD?&$orderby=SEQUENCE desc&$select=CODE,TITLE', sexes: '/DEX_CMS/REF_SEX_COD?&$orderby=SEQUENCE&$select=CODE,TITLE', ageGroups: '/DEX_CMS/REF_AGE_COD?&$orderby=SEQUENCE&$select=CODE,TITLE' }; const fetchPromises = Object.entries(endpoints).map(async ([key, endpoint]) => { const response = await fetch(`${__xmart_odata_api}${endpoint}`); if (!response.ok) throw new Error(`HTTP error! status: ${response.status}`); const data = await response.json(); return [key, data.value.map(item => ({ value: item.CODE || item.CODE_ISO_3, label: item.TITLE || item.NAME_SHORT_EN }))]; }); state.dropdownData = Object.fromEntries(await Promise.all(fetchPromises)); } catch (error) { console.error('Error fetching dropdown data:', error); throw error; } } function createControls() { const controls = [ { id: 'country-select', data: state.dropdownData.countries, stateKey: 'country' }, { id: 'year-select', data: state.dropdownData.years, stateKey: 'year' }, { id: 'sex-select', data: state.dropdownData.sexes, stateKey: 'sex' }, { id: 'age-select', data: state.dropdownData.ageGroups, stateKey: 'ageGroup' } ]; controls.forEach(control => { const select = document.querySelector(`.ghe-top10-widget #${control.id}`); if (select) { control.data.forEach(item => { const option = document.createElement('option'); option.value = item.value; option.textContent = item.label; select.appendChild(option); }); select.addEventListener('change', (e) => handleFilterChange(control.stateKey, e.target.value)); } else { console.error(`Select element not found: ${control.id}`); } }); } function handleFilterChange(filterType, value) { console.log(`Filter changed: ${filterType} = ${value}`); state.filters[filterType] = value; fetchData(); } function toggleChartType() { state.mode = state.mode === 'death' ? 'daly' : 'death'; const chartTypeElement = document.querySelector('.ghe-top10-widget #chart-type'); if (chartTypeElement) { chartTypeElement.textContent = state.mode === 'death' ? 'Death' : 'DALYs'; } fetchData(); } async function fetchData() { showLoading(); updateSubtitle(); const url = buildUrl(); console.log('Fetching data from URL:', url); const cacheKey = url + state.mode; if (cache[cacheKey]) { state.data = cache[cacheKey]; updateVisualization(); hideLoading(); return; } try { const response = await fetch(url); if (!response.ok) { throw new Error(`HTTP error! status: ${response.status}`); } const result = await response.json(); if (result.value.length === 0) { console.warn('No data returned from API for the current filters'); showError('No data available for the selected filters'); return; } state.data = result.value.map(item => ({ name: item.DIM_GHECAUSE_TITLE, value: state.mode === 'daly' ? item.VAL_DALY_RATE100K_NUMERIC : item.VAL_DTHS_RATE100K_NUMERIC, category: item.DIM_GHECAUSE_CODE < 600 ? 'Communicable' : item.DIM_GHECAUSE_CODE < 1510 ? 'Non-communicable' : 'Injuries' })); cache[cacheKey] = state.data; updateVisualization(); } catch (error) { console.error('Error fetching data:', error); showError('Failed to fetch data. Please try again later.'); } finally { hideLoading(); } } function updateVisualization() { createChart(); updateDataTable(); updateODataDownloadLink(buildUrl()); } function buildUrl() { const baseUrl = `${__xmart_odata_api}/${__xmart}/GHE_FULL`; const filter = `FLAG_RANKABLE eq 1 and DIM_COUNTRY_CODE eq '${state.filters.country}' and DIM_SEX_CODE eq '${state.filters.sex}' and DIM_AGEGROUP_CODE eq '${state.filters.ageGroup}' and DIM_YEAR_CODE eq ${state.filters.year}`; const orderBy = state.mode === 'daly' ? 'VAL_DALY_RATE100K_NUMERIC desc' : 'VAL_DTHS_RATE100K_NUMERIC desc'; const select = 'DIM_GHECAUSE_CODE,DIM_GHECAUSE_TITLE,VAL_DALY_RATE100K_NUMERIC,VAL_DTHS_RATE100K_NUMERIC'; return `${baseUrl}?$filter=${filter}&$orderBy=${orderBy}&$select=${select}&$top=10`; } function createChart() { const canvas = document.querySelector('.ghe-top10-widget #myChart'); if (!canvas) { console.error('Chart canvas element not found'); return; } const ctx = canvas.getContext('2d'); const chartData = { labels: state.data.map(d => d.name), datasets: [{ label: state.mode === 'death' ? 'Deaths per 100,000 population' : 'DALYs per 100,000 population', data: state.data.map(d => d.value), backgroundColor: state.data.map(d => colorMap[d.category]), borderColor: state.data.map(d => colorMap[d.category]), borderWidth: 1 }] }; const options = { indexAxis: 'y', responsive: true, maintainAspectRatio: false, plugins: { legend: { display: false }, tooltip: { callbacks: { label: function(context) { let label = context.dataset.label || ''; if (label) { label += ': '; } if (context.parsed.x !== null) { label += context.parsed.x.toFixed(2); } return label; } } }, datalabels: { color: 'white', anchor: 'end', align: 'right', formatter: function(value, context) { return value.toFixed(2); }, font: { weight: 'bold' } } }, scales: { x: { beginAtZero: true, title: { display: true, text: state.mode === 'death' ? 'Deaths per 100,000 population' : 'DALYs per 100,000 population' }, grid: { display: true, color: 'rgba(0, 0, 0, 0.1)' }, ticks: { color: 'rgba(0, 0, 0, 0.7)' } }, y: { title: { display: true, text: 'Cause' }, grid: { display: false }, ticks: { color: 'rgba(0, 0, 0, 0.7)' } } } }; if (chart) { chart.destroy(); } chart = new Chart(ctx, { type: 'bar', data: chartData, options: options, plugins: [ChartDataLabels] }); } function updateDataTable() { const tbody = document.querySelector('.ghe-top10-widget #data-table tbody'); if (!tbody) { console.error('Data table body not found'); return; } tbody.innerHTML = ''; state.data.forEach(item => { const row = tbody.insertRow(); row.insertCell(0).textContent = item.name; row.insertCell(1).textContent = item.value.toFixed(2); row.insertCell(2).textContent = item.category; }); } function updateODataDownloadLink(url) { const downloadLink = document.querySelector('.ghe-top10-widget #odata-download'); if (downloadLink) { downloadLink.href = url; downloadLink.download = `GHE_Top10_${state.filters.country}_${state.filters.year}_${state.filters.sex}_${state.filters.ageGroup}_${state.mode}.csv`; } else { console.error('Download link element not found'); } } function showLoading() { const loadingIndicator = document.querySelector('.ghe-top10-widget #loading-indicator'); if (loadingIndicator) { loadingIndicator.style.display = 'block'; } // Disable controls while loading document.querySelectorAll('.ghe-top10-widget #controls select, .ghe-top10-widget #controls button').forEach(el => { el.disabled = true; }); } function hideLoading() { const loadingIndicator = document.querySelector('.ghe-top10-widget #loading-indicator'); if (loadingIndicator) { loadingIndicator.style.display = 'none'; } // Re-enable controls after loading document.querySelectorAll('.ghe-top10-widget #controls select, .ghe-top10-widget #controls button').forEach(el => { el.disabled = false; }); } function updateSubtitle() { const subtitleElement = document.querySelector('.ghe-top10-widget #subtitle'); if (!subtitleElement) { console.error('Subtitle element not found'); return; } const country = state.dropdownData.countries.find(c => c.value === state.filters.country)?.label || ''; const year = state.filters.year; const sex = state.dropdownData.sexes.find(s => s.value === state.filters.sex)?.label || ''; const ageGroup = state.dropdownData.ageGroups.find(a => a.value === state.filters.ageGroup)?.label || ''; subtitleElement.textContent = `${country}, ${year}, ${sex}, ${ageGroup}`; } function showError(message) { const chartContainer = document.querySelector('.ghe-top10-widget #chart-container'); if (chartContainer) { chartContainer.innerHTML = `<p class="error-message">${message}</p>`; } else { console.error('Chart container not found'); } } return { init: init }; })(); GHETop10.init(); }); </script> <div class="section-heading"> <h2>Data download</h2> </div> <div class="sf-content-block content-block" > <div ><p><strong>About the download files</strong></p><p>&nbsp;</p><p>The latest global, regional and country-level cause-specific mortality estimates for the year 2000, 2010, 2015, 2019, 2020 and 2021 are available for download below.</p><p>Recommended citation: Global Health Estimates 2021: Deaths by Cause, Age, Sex, by Country and by Region, 2000-2021. Geneva, World Health Organization; 2024.</p><p>A summary of data sources and methods is available. Due to changes in data and some methods, the 2000&ndash;2021 estimates are not comparable to previously-released WHO estimates.&nbsp;</p><p>&nbsp;</p><p class="arrowed-link"><a href="https://cdn.who.int/media/docs/default-source/gho-documents/global-health-estimates/ghe2021_cod_methods.pdf?sfvrsn=dca346b7_1">WHO methods and data sources or country-level causes of death, 2000-2021</a> </p></div> </div> <div class="sf-content-block content-block" > <div ><p><strong>&nbsp;</strong></p><p><strong></strong><strong>GLOBAL AND BY REGION&nbsp;</strong></p><p style=""><span style="background-color:initial;font-size:inherit;font-family:inherit;text-transform:inherit;white-space:inherit;word-spacing:normal;caret-color:auto;">Summary tables of mortality estimates by cause, age and sex, globally and by region, 2000&ndash;2021</span><br /></p><div><p class="-sf-direction-ltr" style="direction:ltr;text-align:left;margin-left:30px;"><a href="http://www.who.int/entity/healthinfo/global_burden_disease/GHE2016_Deaths_Global_2000_2016.xls" data-sf-ec-immutable="" class="-sf-direction-ltr" style="direction:ltr;text-align:left;"></a><a target="_blank" href="https://cdn.who.int/media/docs/default-source/gho-documents/global-health-estimates/ghe2021_deaths_global_new2.xlsx?sfvrsn=e1f725b1_2">Global summary estimates</a> <strong>&brvbar;&nbsp;</strong> <a target="_blank" href="https://cdn.who.int/media/docs/default-source/gho-documents/global-health-estimates/ghe2021_deaths_whoregion_new2.xlsx?sfvrsn=a05d8c31_2">WHO regions</a><span style="background-color:transparent;text-align:left;text-transform:inherit;white-space:inherit;word-spacing:normal;caret-color:auto;direction:ltr;" class="-sf-direction-ltr">&nbsp;</span><strong>&brvbar;&nbsp;</strong> <a target="_blank" href="https://cdn.who.int/media/docs/default-source/gho-documents/global-health-estimates/ghe2021_deaths_wbincome_new.xlsx?sfvrsn=6756ba97_2">World Bank income groups</a></p><p class="-sf-direction-ltr" style="direction:ltr;text-align:left;"><span style="background-color:transparent;text-align:inherit;text-transform:inherit;white-space:inherit;word-spacing:normal;caret-color:auto;">&nbsp;</span></p><p class="-sf-direction-ltr" style="direction:ltr;text-align:left;"><span style="background-color:transparent;text-align:inherit;text-transform:inherit;white-space:inherit;word-spacing:normal;caret-color:auto;"></span><strong>BY COUNTRY</strong></p><p>Summary tables of mortality estimates by cause, age and sex, by country, 2000&ndash;2021</p><p style="margin-left:30px;"><strong>Estimated deaths ('000) by age, cause and sex</strong></p><p style="margin-left:30px;"><a target="_blank" href="https://cdn.who.int/media/docs/default-source/gho-documents/global-health-estimates/ghe2021_deaths_bycountry_2000.xlsx?sfvrsn=fad0cc1a_4">WHO Member States, 2000</a>&nbsp;<strong>&brvbar;</strong>&nbsp; <a href="https://cdn.who.int/media/docs/default-source/gho-documents/global-health-estimates/ghe2021_deaths_bycountry_age_sex_2010_new.xlsx?sfvrsn=7b8f1cd0_5">WHO Member States, 2010</a>&nbsp;<strong>&brvbar;</strong>&nbsp; <a target="_blank" href="https://cdn.who.int/media/docs/default-source/gho-documents/global-health-estimates/ghe2021_deaths_bycountry_2015.xlsx?sfvrsn=ef03f276_4">WHO Member States, 2015</a>&nbsp;<strong>&brvbar;</strong>&nbsp; <a target="_blank" href="https://cdn.who.int/media/docs/default-source/gho-documents/global-health-estimates/ghe2021_deaths_bycountry_2019.xlsx?sfvrsn=af73850f_4">WHO Member States, 2019</a>&nbsp;<strong>&brvbar;</strong>&nbsp;&nbsp; <a target="_blank" href="https://cdn.who.int/media/docs/default-source/gho-documents/global-health-estimates/ghe2021_deaths_bycountry_2020.xlsx?sfvrsn=1658d249_4">WHO Member States, 2020</a>&nbsp;<strong>&brvbar;</strong>&nbsp;&nbsp; <a target="_blank" href="https://cdn.who.int/media/docs/default-source/gho-documents/global-health-estimates/ghe2021_deaths_bycountry_2021.xlsx?sfvrsn=91763f5c_4">WHO Member States,&nbsp;2021</a></p><p style="margin-left:30px;"><strong>Death rates<a href="https://cdn.who.int/media/docs/default-source/gho-documents/global-health-estimates/ghe2021_deathrates_bycountry_asdr.xlsx?sfvrsn=d2ead5e5_2"></a></strong></p><p>&nbsp;</p><p style="margin-left:30px;"><a href="https://cdn.who.int/media/docs/default-source/gho-documents/global-health-estimates/ghe2021_deathrates_bycountry_asdr.xlsx?sfvrsn=d2ead5e5_2">WHO Member States, age-standardized death rates, 2021</a>&nbsp;|&nbsp;<a href="https://cdn.who.int/media/docs/default-source/gho-documents/global-health-estimates/ghe2021_deathrates_bycountry_cdr.xlsx?sfvrsn=99b82f0f_1">WHO Member States, crude death rates, 2021</a>&nbsp;</p><br /><p>&nbsp;</p></div></div> </div> <div class="row" data-sf-element="Row"> <div id="PageContent_C059_Col00" class="sf_colsIn col-md-12" data-sf-element="Column 1" data-placeholder-label="Column 1"> <div class="section-heading"> <h2>Leading causes of death and disability</h2> </div> <div class="sf-content-block content-block" > <div ><div>WHO&rsquo;s Global Health Estimates (GHE) provide the latest available data on causes of death and disability globally, by region and country, and by age, sex and income group. They provide key insights on mortality and morbidity trends to support informed decision-making on health policy and resource allocation.&nbsp;</div><div><br /></div><div>These estimates are produced using data from multiple sources, including national vital registration data, latest estimates from WHO technical programmes, United Nations partners and inter-agency groups, as well as the Global Burden of Disease and other scientific studies. 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