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</div> <main id="main" class="site-main" role="main"> <article id="post-4897" class="post-4897 post type-post status-publish format-standard hentry category-general"> <div id="breadcrumb"> <div id="crumbs"><span class="crumb"><a href="https://www.compbio.com">Home</a></span> <i class="fa fa-angle-right"></i> <span class="crumb"><a href="https://www.compbio.com/general/">General</a></span> <i class="fa fa-angle-right"></i> <span class="current">Dermal Immune Mediated Disease</span></div> </div> <div class="entry-content"> <div class="the-content-contain"> <div class="row builder-row content-row"> <div class="medium-12 columns"> <p><img class="wp-image-4905 alignleft" src="https://www.compbio.com/images/CBI-Eblast-Header-Psoriasis-1024x760.jpg?v=1712233281" alt="" width="724" height="537" /></p> <h2>A Model of Psoriasis</h2> <div></div> <div> <p>Psoriasis is a chronic skin condition associated with multiple contributing factors including autoimmune disease. The imiquimod-induced Psoriasis model is particularly translational into the clinic as it has many of the significant markers of human disease, including histopathology of lesions and strong activation of the immune system. CBI’s extensive immunology expertise allows our scientists to implement these translational models to mimic human disease, and our experienced pathologists can analyze the pathology associated with the Psoriasis disease model.</p> </div> <h2 style="font-weight: 400;"></h2> <p> </p> <p> </p> <div> <p><img loading="lazy" class=" wp-image-5634 alignleft" src="https://www.compbio.com/images/Screen-Shot-2022-06-13-at-3.08.39-PM.png?v=1712262976" alt="" width="1062" height="343" srcset="https://www.compbio.com/images/Screen-Shot-2022-06-13-at-3.08.39-PM.png?v=1712262976 1392w, https://www.compbio.com/images/Screen-Shot-2022-06-13-at-3.08.39-PM-300x97.png?v=1712262999 300w, https://www.compbio.com/images/Screen-Shot-2022-06-13-at-3.08.39-PM-1024x331.png?v=1712263010 1024w, https://www.compbio.com/images/Screen-Shot-2022-06-13-at-3.08.39-PM-768x248.png?v=1712263031 768w" sizes="(max-width: 1062px) 100vw, 1062px" /></p> <p> </p> <p> </p> <p> </p> <p><b>Imiquimodis – Induced Dermatitis In Mice:</b></p> </div> <div> <div align="left"></div> <div align="left">• Lesions similar to man</div> <div align="left">• Erythema, swelling and scaling</div> <div align="left">• Histologically similar to man</div> <div align="left">• Responds to similar human therapies</div> </div> <div align="left"></div> <div align="left"></div> <div align="left"></div> <div align="left"></div> <div align="left"></div> <div align="left"></div> <div align="left"></div> <div align="left"></div> <div align="left"></div> <div align="left"></div> <div align="left"></div> <div align="left"><strong></strong></div> <div align="left"><strong></strong></div> <div align="left"></div> <h3 align="left"></h3> <h3 align="left"><strong>CHECK OUT OUR POWERPOINT PRESENTATION:</strong></h3> <div align="left"></div> <div align="left"></div> <div align="left"></div> <div align="left"></div> <div align="left"><strong><a href="https://www.compbio.com/files/CBI-WEB.-Imiquimod-induced-Dermatitis-in-Mice.pdf?v=1712263295">IMIQUIMOD-INDUCED PSORIASIS MODEL IN MICE</a></strong></div> <div align="left"></div> <div align="left"></div> <div align="left"></div> <div align="left"> <h3 align="left"><strong> </strong></h3> <h3 align="left"><strong>CHECK OUT OUR FOUR-PAGE TECHNOLOGY BULLETIN NEWSLETTER:</strong></h3> <div align="left"></div> <div align="left"></div> <div align="left"></div> <div align="left"></div> <div align="left"><a href="https://www.compbio.com/files/CBI-Tec.-Bulletin-Psoriasis-2020.pdf?v=1712263309"><strong>TECHNICAL BULLETIN: A MODEL OF PSORIASIS</strong></a></div> </div> </div> </div> </div> </div> </article> </main> </div> </div> <div class="call-out"> <h3 class="content-left"><span class="line-one">Have a question</span> <span class="line-two">or need a quote?</span></h3> <svg version="1.1" id="Layer_1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 100 85" style="enable-background:new 0 0 100 85;" xml:space="preserve"> <style type="text/css"> .st0{fill:#FFFFFF;} </style> <g> <path class="st0" d="M64.3,0.5H16c-8.8,0-16,7.2-16,16V44c0,8.4,6.6,15.4,14.9,16l-3.7,17.4L31.6,60h8.8V43.9 c0-8.7,7.1-15.8,15.8-15.8h24.2V16.5C80.3,7.7,73.1,0.5,64.3,0.5z"/> <path class="st0" d="M89.1,33h-33c-6,0-10.9,4.9-10.9,10.9v18.8c0,6,4.9,10.9,10.9,10.9h22.4l13.9,11.8l-2.5-11.9 c5.7-0.4,10.2-5.1,10.2-10.9V44C100,38,95.1,33,89.1,33z M85.5,49.3c2.2,0,4,1.8,4,4.1c0,2.2-1.8,4.1-4,4.1s-4-1.8-4-4.1 C81.5,51.1,83.3,49.3,85.5,49.3z M59.6,57.4c-2.2,0-4-1.8-4-4.1c0-2.2,1.8-4.1,4-4.1c2.2,0,4,1.8,4,4.1 C63.7,55.6,61.9,57.4,59.6,57.4z M68.5,53.4c0-2.2,1.8-4.1,4-4.1s4,1.8,4,4.1c0,2.2-1.8,4.1-4,4.1S68.5,55.6,68.5,53.4z"/> </g> </svg> <h3 class="content-right"><span>We can help!</span> <a href="https://www.compbio.com/contact-us/"><span class="cta-btn">Contact us</span></a></h3> </div> </div> </div> <footer id="colophon" class="site-footer row"> <div class="site-info medium-12 columns"> Comparative Biosciences, Inc. · <strong>Phone: 888-994-4879</strong><br> Copyright 2024 Comparative Biosciences, Inc. 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