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id="content-inner" class="site-content-inner row multi-columns-row"> <div id="primary" class="content-area col-md-9 col-lg-9 col-xs-12"> <main id="main" class="site-main"> <article id="post-8946" class="ts-no-featured-content themestek-box-blog-classic post-8946 post type-post status-publish format-standard hentry category-press-releases" > <div class="ts-blog-classic-featured-wrapper"> <div class="ts-blog-classic-datebox-overlay"> <div class="ts-blog-classic-dbox-date">22</div> <div class="ts-blog-classic-dbox-month">Apr</div> </div> </div> <div class="ts-blog-classic-box-content ">  <div class="ts-featured-meta-wrapper ts-featured-overlay"> <div class="ts-blog-post-date"> <span class="ts-meta-line"><span class="screen-reader-text ts-hide">Date </span> <i class="ts-labtechco-icon-clock"></i> <a href="https://lexariabioscience.com/2021/04/22/lexaria-commences-human-clinical-hypertension-study/">April 22, 2021</a></span> </div> <div class="ts-blog-post-cat ts-blog-post-cat-above-title"> <span class="ts-meta-line cat-links"><span class="screen-reader-text ts-hide">Categories </span> <i class="ts-labtechco-icon-category"></i> <a href="https://lexariabioscience.com/category/press-releases/">Press Releases</a></span> </div> <div class="themestek-box-title"><h4><a href="https://lexariabioscience.com/2021/04/22/lexaria-commences-human-clinical-hypertension-study/">Lexaria Commences Human Clinical Hypertension Study</a></h4></div> </div>  <div class="entry-content"> <div class="themestek-box-desc-text"><div class="b2iNewsItemBodyDiv"><ul><br /> <li><strong><i>Study to examine DehydraTECH<sup>TM</sup> CBD's ability to control blood pressure</i></strong></li><br /> <li><strong><i>First of three human clinical studies hoped to validate Lexaria's patented technology for hypertension relief</i></strong></li><br /> </ul><br /> <br /> <p><b>KELOWNA, BC / April 22, 2021</b> / Lexaria Bioscience Corp. (NASDAQ:LEXX)(NASDAQ:LEXXW)(CSE:LXX) (the "Company" or "Lexaria"), a global innovator in drug delivery platforms, announces that its human clinical hypertension study HYPER-H21-1 is officially underway. Lexaria's patented DehydraTECH CBD formulation will be examined to assess its ability to control blood pressure and assess impact on inflammation.</p><br /> <br /> <p>"We are very pleased that dosing of human volunteers as part of Lexaria's hypertension study has begun," said Lexaria CEO Mr. Chris Bunka. "Dosing is expected to be completed, on schedule, within several weeks, and we may be in a position to report preliminary data in July or thereabouts. Despite challenges in launching a human clinical study during a global pandemic, Lexaria's Europe-based research partners have done an excellent job of balancing the need for scientific validation for a potential new hypertension treatment, with the required safety protocols currently in place."</p><br /> <br /> <p>HYPER-H21-1 is a randomized, double-blinded, controlled human clinical study expected to involve 24 human volunteers with symptoms of either pre-hypertension, or mild hypertension. A single 300mg dose of an advanced DehydraTECH<sup>TM</sup> 2.0 CBD formulation will be evaluated relative to a concentration-matched control without Lexaria's DehydraTECH enhancements.</p><br /> <br /> <p>Time series blood pressure and heart rate analyses are the primary objectives of this study. Secondary objectives include speed and rate of absorption of the CBD and its main metabolites (pharmacokinetics or "PK" assessments), as well as evaluation of inflammatory markers associated with cardiovascular disease and gold-standard biomarkers of nitric oxide. This latter measure provides mechanistic insight into the anticipated reduction in blood pressure via vasodilation.</p><br /> <br /> <p>These inflammatory marker assessments may also be applicable to Lexaria's research initiatives in the antiviral therapeutics space whereby effective anti-inflammatory therapies are also useful in treating diseases like COVID-19 or other common pro-inflammatory conditions.</p><br /> <br /> <p>Since a large array of data points will be generated and analyzed, final reporting on this study is likely to be reported in early September.</p><br /> <br /> <p>There are five studies in Lexaria's 2021 hypertension program which are expected to generate data required to further support the validity of using DehydraTECH-processed CBD as a potential hypertension treatment across various applications. Lexaria has received 18 granted patents internationally, including issuances in the European Union and Australia specifically to use DehydraTECH-processed CBD to treat heart disease.</p><br /> <br /> <p><b>About Lexaria Bioscience Corp.</b><br><br /> Lexaria Bioscience Corp.'s proprietary drug delivery technology, DehydraTECH™, improves the way active pharmaceutical ingredients (APIs) enter the bloodstream by promoting healthier oral ingestion methods and increasing the effectiveness of fat-soluble active molecules, thereby lowering overall dosing. The Company's technology can be applied to many different ingestible product formats, including foods, beverages, oral suspensions, tablets, and capsules. DehydraTECH has repeatedly demonstrated since 2016 with cannabinoids and nicotine the ability to increase bio-absorption by up to 5-10x, reduce time of onset from 1 - 2 hours to minutes, and mask unwanted tastes; and is planned to be further evaluated for orally administered bioactive molecules, including anti-virals, cannabinoids, vitamins, non-steroidal anti-inflammatory drugs (NSAIDs), and nicotine. Lexaria has licensed DehydraTECH to multiple companies including a world-leading tobacco producer for the development of smokeless, oral-based nicotine products and for use in industries that produce cannabinoid beverages, edibles, and oral products. Lexaria operates a licensed in-house research laboratory and holds a robust intellectual property portfolio with 18 patents granted and approximately 60 patents pending worldwide. For more information, please visit <a href="https://pr.report/z5qNdB-j">www.lexariabioscience.com</a>.</p><br /> <br /> <p><b>CAUTION REGARDING FORWARD-LOOKING STATEMENTS</b><br><br /> This press release includes forward-looking statements. Statements as such term is defined under applicable securities laws. These statements may be identified by words such as "anticipate," "if," "believe," "plan," "estimate," "expect," "intend," "may," "could," "should," "will," and other similar expressions. Such forward-looking statements in this press release include, but are not limited to, statements by the company relating the Company's ability to carry out research initiatives, receive regulatory approvals or grants or experience positive effects or results from any research or study. Such forward-looking statements are estimates reflecting the Company's best judgment based upon current information and involve a number of risks and uncertainties, and there can be no assurance that the Company will actually achieve the plans, intentions, or expectations disclosed in these forward-looking statements. As such, you should not place undue reliance on these forward-looking statements. Factors which could cause actual results to differ materially from those estimated by the Company include, but are not limited to, government regulation and regulatory approvals, managing and maintaining growth, the effect of adverse publicity, litigation, competition, scientific discovery, the patent application and approval process, potential adverse effects arising from the testing or use of products utilizing the DehydraTECH technology, the Company's ability to maintain existing collaborations and realize the benefits thereof, delays or cancellations of planned R&D that could occur related to pandemics or for other reasons, and other factors which may be identified from time to time in the Company's public announcements and periodic filings with the US Securities and Exchange Commission on EDGAR. There is no assurance that any of Lexaria's postulated uses, benefits, or advantages for the patented and patent-pending technology will in fact be realized in any manner or in any part. No statement herein has been evaluated by the Food and Drug Administration (FDA). Lexaria-associated products are not intended to diagnose, treat, cure or prevent any disease. Any forward-looking statements contained in this release speak only as of the date hereof, and the Company expressly disclaims any obligation to update any forward-looking statements contained herein, whether as a result of any new information, future events, changed circumstances or otherwise, except as otherwise required by law.</p><br /> <br /> <p><i>The CSE has not reviewed and does not accept responsibility for the adequacy or accuracy of this release.</i></p><br /> <br /> <p><b>INVESTOR CONTACT: </b><br><br /> <a href="/cdn-cgi/l/email-protection#2f465d6f434a574e5d464e4d46405c4c464a414c4a014c4042"><span class="__cf_email__" data-cfemail="553c271539302d34273c34373c3a26363c303b36307b363a38">[email protected]</span></a><br><br /> Phone: 866-221-3341</p><br /> <br /> <p><strong>SOURCE: </strong>Lexaria Bioscience Corp.</p><br /> <br><br>View source version on accesswire.com: <br><a href='https://www.accesswire.com/641682/Lexaria-Commences-Human-Clinical-Hypertension-Study'>https://www.accesswire.com/641682/Lexaria-Commences-Human-Clinical-Hypertension-Study</a><br><br><img src='https://www.accesswire.com/img.ashx?id=641682' /></div></div> <div class="themestek-blog-classic-footer-readmore"> <div class="themestek-blogbox-footer-left"><a href="https://lexariabioscience.com/2021/04/22/lexaria-commences-human-clinical-hypertension-study/">Read More</a></div> </div> <div class="ts-footer-meta-wrapper"> <span class="ts-footer-meta-line-w ts-footer-meta-line-comments"> <a href="https://lexariabioscience.com/2021/04/22/lexaria-commences-human-clinical-hypertension-study/"> <i class="ts-labtechco-icon-comment-1"></i> <span class="comments"> 0 Comments </span> </a> </span> <span class="ts-footer-meta-line-w ts-footer-meta-line-author"> <span class="author vcard"> <span class="screen-reader-text ts-hide">Author </span> <a class="url fn n" href="https://lexariabioscience.com/author/mmcdonald/"><i class="ts-labtechco-icon-user"></i> mmcdonald</a> </span> </span> </div> </div> </div> </article> <article id="post-8947" class="ts-no-featured-content themestek-box-blog-classic post-8947 post type-post status-publish format-standard hentry category-press-releases" > <div class="ts-blog-classic-featured-wrapper"> <div class="ts-blog-classic-datebox-overlay"> <div class="ts-blog-classic-dbox-date">15</div> <div class="ts-blog-classic-dbox-month">Apr</div> </div> </div> <div class="ts-blog-classic-box-content ">  <div class="ts-featured-meta-wrapper ts-featured-overlay"> <div class="ts-blog-post-date"> <span class="ts-meta-line"><span class="screen-reader-text ts-hide">Date </span> <i class="ts-labtechco-icon-clock"></i> <a href="https://lexariabioscience.com/2021/04/15/lexaria-appoints-new-chief-financial-officer-and-issues-consultant-warrants/">April 15, 2021</a></span> </div> <div class="ts-blog-post-cat ts-blog-post-cat-above-title"> <span class="ts-meta-line cat-links"><span class="screen-reader-text ts-hide">Categories </span> <i class="ts-labtechco-icon-category"></i> <a href="https://lexariabioscience.com/category/press-releases/">Press Releases</a></span> </div> <div class="themestek-box-title"><h4><a href="https://lexariabioscience.com/2021/04/15/lexaria-appoints-new-chief-financial-officer-and-issues-consultant-warrants/">Lexaria Appoints New Chief Financial Officer and Issues Consultant Warrants</a></h4></div> </div>  <div class="entry-content"> <div class="themestek-box-desc-text"><div class="b2iNewsItemBodyDiv"><p><strong>KELOWNA, BC / April 15, 2021 / </strong>Lexaria Bioscience Corp. (Nasdaq:LEXX)(Nasdaq:LEXXW)(CSE:LXX) (the "Company" or "Lexaria"), a global innovator in drug delivery platforms, announces the appointment of a new Chief Financial Officer and the issuance of share purchase warrants to third party consultants.</p><br /> <br /> <p>Lexaria is pleased to announce that effective April 15, 2021, Gregory Downey will be assuming the role of Chief Financial Officer of the Company. During the past two years, Mr. Downey has been engaged by the Company as its Controller and has intimate knowledge regarding the Company's business and finances. Mr. Downey brings a wealth of experience to Lexaria, having served as the Chief Financial Officer of several public companies during the past ten years. Mr. Downey holds a Certified Management Accountant designation and is a member of the Chartered Professional Accountants of British Columbia.</p><br /> <br /> <p>In the position as Chief Financial Officer, Mr. Downey will be compensated with a base annual salary of CDN$144,000, with an annual increase of 10%, an option grant for the issuance of up to 12,000 common shares, and other customary incentives.</p><br /> <br /> <p>The Company is grateful to outgoing CFO, Mr. Allan Spissinger, for his many contributions and wishes him continued success in his future endeavours.</p><br /> <br /> <p>The Company also announces that effective on April 16, 2021, it will be issuing share purchase warrants (the "<b>Warrants</b>") for the issuance of up to an aggregate 300,000 common shares to three unrelated third party consultants. The Warrants will be exercisable for a period of three years ending on April 16, 2024 at an exercise price of US$9.00 per share. The shares issuable upon exercise of the Warrants will be restricted securities pursuant to US securities laws.</p><br /> <br /> <p><b>About Lexaria Bioscience Corp.</b></p><br /> <br /> <p>Lexaria Bioscience Corp.'s proprietary drug delivery technology, DehydraTECH™, improves the way active pharmaceutical ingredients (APIs) enter the bloodstream by promoting healthier oral ingestion methods and increasing the effectiveness of fat-soluble active molecules, thereby lowering overall dosing. The Company's technology can be applied to many different ingestible product formats, including foods, beverages, oral suspensions, tablets, and capsules. DehydraTECH has repeatedly demonstrated since 2016 with cannabinoids and nicotine the ability to increase bio-absorption by up to 5-10x, reduce time of onset from 1 - 2 hours to minutes, and mask unwanted tastes; and is planned to be further evaluated for orally administered bioactive molecules, including anti-virals, cannabinoids, vitamins, non-steroidal anti-inflammatory drugs (NSAIDs), and nicotine. Lexaria has licensed DehydraTECH to multiple companies including a world-leading tobacco producer for the development of smokeless, oral-based nicotine products and for use in industries that produce cannabinoid beverages, edibles, and oral products. Lexaria operates a licensed in-house research laboratory and holds a robust intellectual property portfolio with 18 patents granted and approximately 60 patents pending worldwide. For more information, please visit <a href="https://pr.report/CY81zvSP">www.lexariabioscience.com</a>.</p><br /> <br /> <p><b>CAUTION REGARDING FORWARD-LOOKING STATEMENTS</b></p><br /> <br /> <p>This press release includes forward-looking statements. Statements as such term is defined under applicable securities laws. These statements may be identified by words such as "anticipate," "if," "believe," "plan," "estimate," "expect," "intend," "may," "could," "should," "will," and other similar expressions. Such forward-looking statements in this press release include, but are not limited to, statements by the company relating the Company's ability to carry out research initiatives, receive regulatory approvals or grants or experience positive effects or results from any research or study. Such forward-looking statements are estimates reflecting the Company's best judgment based upon current information and involve a number of risks and uncertainties, and there can be no assurance that the Company will actually achieve the plans, intentions, or expectations disclosed in these forward-looking statements. As such, you should not place undue reliance on these forward-looking statements. Factors which could cause actual results to differ materially from those estimated by the Company include, but are not limited to, government regulation and regulatory approvals, managing and maintaining growth, the effect of adverse publicity, litigation, competition, scientific discovery, the patent application and approval process, potential adverse effects arising from the testing or use of products utilizing the DehydraTECH technology, the Company's ability to maintain existing collaborations and realize the benefits thereof, delays or cancellations of planned R&D that could occur related to pandemics or for other reasons, and other factors which may be identified from time to time in the Company's public announcements and periodic filings with the US Securities and Exchange Commission on EDGAR. There is no assurance that any of Lexaria's postulated uses, benefits, or advantages for the patented and patent-pending technology will in fact be realized in any manner or in any part. No statement herein has been evaluated by the Food and Drug Administration (FDA). Lexaria-associated products are not intended to diagnose, treat, cure or prevent any disease. Any forward-looking statements contained in this release speak only as of the date hereof, and the Company expressly disclaims any obligation to update any forward-looking statements contained herein, whether as a result of any new information, future events, changed circumstances or otherwise, except as otherwise required by law.</p><br /> <br /> <p><i>The CSE has not reviewed and does not accept responsibility for the adequacy or accuracy of this release.</i></p><br /> <br /> <p><b>INVESTOR CONTACT:</b></p><br /> <br /> <p><a href="/cdn-cgi/l/email-protection#78110a38141d00190a11191a11170b1b111d161b1d561b1715"><span class="__cf_email__" data-cfemail="9af3e8daf6ffe2fbe8f3fbf8f3f5e9f9f3fff4f9ffb4f9f5f7">[email protected]</span></a><br><br /> Phone: 866-221-3341</p><br /> <br /> <p><strong>SOURCE:</strong> Lexaria Bioscience Corp.</p><br /> <br><br>View source version on accesswire.com: <br><a href='https://www.accesswire.com/640499/Lexaria-Appoints-New-Chief-Financial-Officer-and-Issues-Consultant-Warrants'>https://www.accesswire.com/640499/Lexaria-Appoints-New-Chief-Financial-Officer-and-Issues-Consultant-Warrants</a><br><br><img src='https://www.accesswire.com/img.ashx?id=640499' /></div></div> <div class="themestek-blog-classic-footer-readmore"> <div class="themestek-blogbox-footer-left"><a href="https://lexariabioscience.com/2021/04/15/lexaria-appoints-new-chief-financial-officer-and-issues-consultant-warrants/">Read More</a></div> </div> <div class="ts-footer-meta-wrapper"> <span class="ts-footer-meta-line-w ts-footer-meta-line-comments"> <a href="https://lexariabioscience.com/2021/04/15/lexaria-appoints-new-chief-financial-officer-and-issues-consultant-warrants/"> <i class="ts-labtechco-icon-comment-1"></i> <span class="comments"> 0 Comments </span> </a> </span> <span class="ts-footer-meta-line-w ts-footer-meta-line-author"> <span class="author vcard"> <span class="screen-reader-text ts-hide">Author </span> <a class="url fn n" href="https://lexariabioscience.com/author/mmcdonald/"><i class="ts-labtechco-icon-user"></i> mmcdonald</a> </span> </span> </div> </div> </div> </article> <article id="post-8948" class="ts-no-featured-content themestek-box-blog-classic post-8948 post type-post status-publish format-standard hentry category-press-releases" > <div class="ts-blog-classic-featured-wrapper"> <div class="ts-blog-classic-datebox-overlay"> <div class="ts-blog-classic-dbox-date">14</div> <div class="ts-blog-classic-dbox-month">Apr</div> </div> </div> <div class="ts-blog-classic-box-content ">  <div class="ts-featured-meta-wrapper ts-featured-overlay"> <div class="ts-blog-post-date"> <span class="ts-meta-line"><span class="screen-reader-text ts-hide">Date </span> <i class="ts-labtechco-icon-clock"></i> <a href="https://lexariabioscience.com/2021/04/14/lexarias-dehydratechtm-technology-utilized-in-amaris-everyday-calm-named-a-top-cbd-product-pick-by-new-hope-network/">April 14, 2021</a></span> </div> <div class="ts-blog-post-cat ts-blog-post-cat-above-title"> <span class="ts-meta-line cat-links"><span class="screen-reader-text ts-hide">Categories </span> <i class="ts-labtechco-icon-category"></i> <a href="https://lexariabioscience.com/category/press-releases/">Press Releases</a></span> </div> <div class="themestek-box-title"><h4><a href="https://lexariabioscience.com/2021/04/14/lexarias-dehydratechtm-technology-utilized-in-amaris-everyday-calm-named-a-top-cbd-product-pick-by-new-hope-network/">Lexaria’s DehydraTECHTM Technology Utilized in Amari’s “Everyday Calm,” Named a Top CBD Product Pick by New Hope Network</a></h4></div> </div>  <div class="entry-content"> <div class="themestek-box-desc-text"><div class="b2iNewsItemBodyDiv"><ul><br /> <li><strong><i>DehydraTECH<sup>TM</sup> Powers Amari's Award-Winning Products </i></strong></li><br /> </ul><br /> <br /> <p><b>KELOWNA, BC / April 14, 2021 /</b> Lexaria Bioscience Corp. (NASDAQ:LEXX)(NASDAQ:LEXXW)(CSE:LXX) (the "Company" or "Lexaria"), a global innovator in drug delivery platforms, announced that its corporate client Amari Corp.'s "Everyday Calm" CBD product was named a <a href="https://pr.report/BpXCSfVP">Top CBD Product Pick</a> by <a href="https://pr.report/K6irmTUd">New Hope Network</a>, host of the industry-leading Natural Products Expo conference events. Hundreds of CBD products competed to be among "New Hope Network editors' Top Picks for 2020".</p><br /> <br /> <p style="text-align: center"><img height="333" src="https://www.accesswire.com/users/newswire/images/640240/image-20210413155918-1.png" width="500"></p><br /> <br /> <p>Eric Gricus, CEO and Founder of Amari, commented, "Amari went through an extensive selection process for our CBD technology supplier. Lexaria exceeded our expectations for product quality, service, and pricing. We are thrilled to have the Lexaria team working with Amari to help us develop <a href="https://pr.report/zf1hswLI">products our customers love</a> and to win industry accolades."</p><br /> <br /> <p>Lexaria's DehydraTECH<sup>TM</sup> technology delivers CBD more quickly and effectively, as evidenced in repeated studies, to enhance consumer satisfaction and strengthen brand loyalty.</p><br /> <br /> <p>"Lexaria is delighted to have been able to work with Amari and their award-winning products," said Chris Bunka, CEO of Lexaria. "DehydraTECH is gaining more widespread consumer support, and we expect to see products utilizing DehydraTECH technology in more and more stores across America as the year unfolds."</p><br /> <br /> <p><b>About Lexaria Bioscience Corp.</b></p><br /> <br /> <p>Lexaria Bioscience Corp.'s proprietary drug delivery technology, DehydraTECH™, improves the way active pharmaceutical ingredients (APIs) enter the bloodstream by promoting healthier oral ingestion methods and increasing the effectiveness of fat-soluble active molecules, thereby lowering overall dosing. The Company's technology can be applied to many different ingestible product formats, including foods, beverages, oral suspensions, tablets, and capsules. DehydraTECH has repeatedly demonstrated since 2016 with cannabinoids and nicotine the ability to increase bio-absorption by up to 5-10x, reduce time of onset from 1 - 2 hours to minutes, and mask unwanted tastes; and is planned to be further evaluated for orally administered bioactive molecules, including anti-virals, cannabinoids, vitamins, non-steroidal anti-inflammatory drugs (NSAIDs), and nicotine. Lexaria has licensed DehydraTECH to multiple companies, including a world-leading tobacco producer, for the development of smokeless, oral-based nicotine products and for use in industries that produce cannabinoid beverages, edibles, and oral products. Lexaria operates a licensed in-house research laboratory and holds a robust intellectual property portfolio with 18 patents granted and approximately 60 patents pending worldwide. For more information, please visit <a href="https://pr.report/rle4nO6o">www.lexariabioscience.com</a>.</p><br /> <br /> <p><b>About Amari</b></p><br /> <br /> <p>Founded in 2019, Amari was launched by outdoor enthusiast Eric Gricus for people like him. People who love to be active, but who may have noticed as they get older that the spirit is willing, but the body often has aches and pains and soreness after a day of hiking, skiing, or rafting. To create the product, Eric leveraged his more than 10 years' experience working with early-stage CPG companies and commercializing research from a university setting. Amari formulas blend science and technology to provide authentic, plant-based remedies that deliver tangible benefits to support a lifestyle of wellness and vitality while being rooted in transparency and extensive quality controls.</p><br /> <br /> <p><b>CAUTION REGARDING FORWARD-LOOKING STATEMENTS</b></p><br /> <br /> <p>This press release includes forward-looking statements. Statements as such term is defined under applicable securities laws. These statements may be identified by words such as "anticipate," "if," "believe," "plan," "estimate," "expect," "intend," "may," "could," "should," "will," and other similar expressions. Such forward-looking statements in this press release include, but are not limited to, statements by the company relating the Company's ability to carry out research initiatives, receive regulatory approvals or grants, or experience positive effects or results from any research or study. Such forward-looking statements are estimates reflecting the Company's best judgment based upon current information and involve a number of risks and uncertainties, and there can be no assurance that the Company will actually achieve the plans, intentions, or expectations disclosed in these forward-looking statements. As such, you should not place undue reliance on these forward-looking statements. Factors which could cause actual results to differ materially from those estimated by the Company include, but are not limited to, government regulation and regulatory approvals, managing and maintaining growth, the effect of adverse publicity, litigation, competition, scientific discovery, the patent application, and approval process, potential adverse effects arising from the testing or use of products utilizing the DehydraTECH technology, the Company's ability to maintain existing collaborations and realize the benefits thereof, delays or cancellations of planned R&D that could occur related to pandemics or for other reasons, and other factors which may be identified from time to time in the Company's public announcements and periodic filings with the US Securities and Exchange Commission on EDGAR. There is no assurance that any of Lexaria's postulated uses, benefits, or advantages for the patented and patent-pending technology will, in fact, be realized in any manner or in any part. No statement herein has been evaluated by the Food and Drug Administration (FDA). Lexaria-associated products are not intended to diagnose, treat, cure or prevent any disease. Any forward-looking statements contained in this release speak only as of the date hereof, and the Company expressly disclaims any obligation to update any forward-looking statements contained herein, whether as a result of any new information, future events, changed circumstances, or otherwise, except as otherwise required by law.</p><br /> <br /> <p><i>The CSE has not reviewed and does not accept responsibility for the adequacy or accuracy of this release.</i></p><br /> <br /> <p><b>INVESTOR CONTACT:</b><br><br /> <a href="/cdn-cgi/l/email-protection#2c455e6c4049544d5e454d4e45435f4f4549424f49024f4341"><span class="__cf_email__" data-cfemail="97fee5d7fbf2eff6e5fef6f5fef8e4f4fef2f9f4f2b9f4f8fa">[email protected]</span></a><br><br /> Phone: 866-221-3341</p><br /> <br /> <p><strong>SOURCE: </strong>Lexaria Bioscience Corp.</p><br /> <br><br>View source version on accesswire.com: <br><a href='https://www.accesswire.com/640240/Lexarias-DehydraTECHTM-Technology-Utilized-in-Amaris-Everyday-Calm-Named-a-Top-CBD-Product-Pick-by-New-Hope-Network'>https://www.accesswire.com/640240/Lexarias-DehydraTECHTM-Technology-Utilized-in-Amaris-Everyday-Calm-Named-a-Top-CBD-Product-Pick-by-New-Hope-Network</a><br><br><img src='https://www.accesswire.com/img.ashx?id=640240' /></div></div> <div class="themestek-blog-classic-footer-readmore"> <div class="themestek-blogbox-footer-left"><a href="https://lexariabioscience.com/2021/04/14/lexarias-dehydratechtm-technology-utilized-in-amaris-everyday-calm-named-a-top-cbd-product-pick-by-new-hope-network/">Read More</a></div> </div> <div class="ts-footer-meta-wrapper"> <span class="ts-footer-meta-line-w ts-footer-meta-line-comments"> <a href="https://lexariabioscience.com/2021/04/14/lexarias-dehydratechtm-technology-utilized-in-amaris-everyday-calm-named-a-top-cbd-product-pick-by-new-hope-network/"> <i class="ts-labtechco-icon-comment-1"></i> <span class="comments"> 0 Comments </span> </a> </span> <span class="ts-footer-meta-line-w ts-footer-meta-line-author"> <span class="author vcard"> <span class="screen-reader-text ts-hide">Author </span> <a class="url fn n" href="https://lexariabioscience.com/author/mmcdonald/"><i class="ts-labtechco-icon-user"></i> mmcdonald</a> </span> </span> </div> </div> </div> </article> <article id="post-8949" class="ts-no-featured-content themestek-box-blog-classic post-8949 post type-post status-publish format-standard hentry category-press-releases" > <div class="ts-blog-classic-featured-wrapper"> <div class="ts-blog-classic-datebox-overlay"> <div class="ts-blog-classic-dbox-date">06</div> <div class="ts-blog-classic-dbox-month">Apr</div> </div> </div> <div class="ts-blog-classic-box-content ">  <div class="ts-featured-meta-wrapper ts-featured-overlay"> <div class="ts-blog-post-date"> <span class="ts-meta-line"><span class="screen-reader-text ts-hide">Date </span> <i class="ts-labtechco-icon-clock"></i> <a href="https://lexariabioscience.com/2021/04/06/lexaria-to-evaluate-dehydratechtm-in-multiple-new-markets/">April 6, 2021</a></span> </div> <div class="ts-blog-post-cat ts-blog-post-cat-above-title"> <span class="ts-meta-line cat-links"><span class="screen-reader-text ts-hide">Categories </span> <i class="ts-labtechco-icon-category"></i> <a href="https://lexariabioscience.com/category/press-releases/">Press Releases</a></span> </div> <div class="themestek-box-title"><h4><a href="https://lexariabioscience.com/2021/04/06/lexaria-to-evaluate-dehydratechtm-in-multiple-new-markets/">Lexaria to Evaluate DehydraTECH(TM) in Multiple New Markets</a></h4></div> </div>  <div class="entry-content"> <div class="themestek-box-desc-text"><div class="b2iNewsItemBodyDiv"><ul><br /> <li><strong><i>Undertaking new 2021 R&D programs in additional drug markets with combined market potential of $87 Billion.</i></strong></li><br /> </ul><br /> <br /> <p><b>KELOWNA, BC / ACCESSWIRE</b> <strong>/</strong><b> April 6, 2021</b> <strong>/</strong> Lexaria Bioscience Corp. (NASDAQ:LEXX)(NASDAQ:LEXXW)(CSE:LXX) (the "Company" or "Lexaria"), a global innovator in drug delivery platforms, will begin important new applied research and development (R&D) study programs planned in 2021.</p><br /> <br /> <p>Lexaria's new study programs will target four drug markets, including NSAIDs, nicotine replacement therapies, tetrahydrocannabinol, and erectile dysfunction. Each of the studies will evaluate the rate of absorption and speed (pharmacokinetics or "PK" assessments) with which various new enhanced DehydraTECH<sup>TM</sup> experimental formulations - "DehydraTECH 2.0" - deliver the drugs being studied into the bloodstream and, in some cases, the brain, after oral dosing. Evidencing improvements in delivery efficiencies or reductions in time required to deliver drugs into bloodstream and brain is intended to support further study and commercial exploitation through prospective pharmaceutical industry strategic partnering.</p><br /> <br /> <p>"Our 2021 study program - already the largest in our company's history - is growing," commented Chris Bunka, CEO of Lexaria. "All of our studies are designed to generate must-have data allowing us to have more meaningful business discussions with various industry leaders and, as such, can shorten the time required for positive commercial developments."</p><br /> <br /> <p><b>Ibuprofen (such as Advil) and Naproxen (such as Aleve): NSAID-A21-1. </b></p><br /> <br /> <p>Test articles are planned to be manufactured in April, and animal dosing is expected in July. The global NSAID market was US$15.6 Billion in 2019,and is <a href="https://pr.report/0z5eFiTV">expected to grow to $24.4 Billion</a> in 2027. Although NSAIDs are in widespread use, they can cause <a href="https://pr.report/uGzSIfAp">serious side effects</a> such as gastrointestinal toxicity, irreversible kidney damage, and <a href="https://pr.report/j4O1U2kR">16,500 deaths per year</a>. Lexaria will investigate whether DehydraTECH-processed NSAIDs might achieve higher bioavailability and brain uptake than conventional formulations and, in turn, be able to be used at lower dosage levels in order to lower unwanted side effects. Lexaria has selected ibuprofen and naproxen for this exercise as two of the most common NSAIDs in use today, predominantly for management of chronic inflammation and pain, respectively. DehydraTECH for oral NSAID delivery is covered by existing granted Lexaria patents in the USA and internationally as well as additional patent applications pending globally.</p><br /> <br /> <p><b>THC: THC-A21-1</b>.</p><br /> <br /> <p>Test articles are planned to be manufactured in July, and animal dosing is expected in August/September. Lexaria has a successful track record through strategic partners and licensees who use DehydraTECH technology and have demonstrated improved delivery and performance of tetrahydrocannabinol ("THC") in both subjective human studies and marketed consumer packaged goods product offerings. Furthermore, Lexaria has repeatedly demonstrated that DehydraTECH-processed cannabidiol (CBD) (another common cannabinoid) has superior delivery characteristics into the bloodstream and brain compared to generic CBD and expects to generate similar results with THC. Successful results from this study will support efforts to commercialize DehydraTECH within the registered THC industry. The global licensed dispensary market for cannabis is projected <a href="https://pr.report/78GJhNmt">to be $40.6 Billion</a> in 2024. DehydraTECH for oral THC delivery is covered by existing granted Lexaria patents in the USA and internationally as well as additional patent applications pending globally. Lexaria divested certain of its THC-related business assets as it prepared for its uplisting to the Nasdaq marketplace, however, it retained all rights to use its DehydraTECH technology with THC related to pharmaceutical purposes or registered drugs within its wholly-owned subsidiary Lexaria Pharmaceutical Corp.</p><br /> <br /> <p><b>Oral Nicotine: NIC-C21-1</b></p><br /> <br /> <p>Test articles have been manufactured, and dosing is expected in September/October. The global market for smokeless tobacco and nicotine replacement therapy (NRT) pharmaceutical products <a href="https://pr.report/zCLRM8hJ">was $15.5 Billion</a> in 2018. Lexaria has repeatedly demonstrated that DehydraTECH-processed nicotine has superior delivery characteristics compared to generic nicotine when dosed orally and swallowed for intestinal delivery to the bloodstream. Lexaria's limited subjective human testing utilizing DehydraTECH-processed nicotine formulations have demonstrated nicotine absorption and onset of nicotine effectiveness in as little as 1.5-4 minutes after an oral dose compared to average 8-10 minutes with comparable pouches. The upcoming PK test will measure the delivery of nicotine directly into <a href="https://pr.report/YaWmJ15l">oral mucosal tissues</a> to evaluate potential superior delivery characteristics without the need to swallow. Both cigarette and e-cigarette sales are trending lower due to well-publicized issues regarding health; whereas oral nicotine products were the first ever to receive an <a href="https://pr.report/VdFQnTuq">FDA reduced risk notice</a>. Modern o<a href="https://pr.report/xM8B01c5">ral nicotine products contain no tobacco</a>, unlike older consumer products which contain moist tobacco. DehydraTECH for oral nicotine is covered by existing granted Lexaria patents in the USA and internationally as well as additional patent applications pending globally.</p><br /> <br /> <p><b>Sildenafil (such as Viagra): PDE5-A21-1 </b></p><br /> <br /> <p>Test article manufacturing is planned for October, and animal dosing is expected in November/December. The erectile dysfunction market was worth $4.8 Billion in 2018 and <a href="https://pr.report/DpGvSnk5">expected to reach $7.1 billion</a> in 2024. Phosphodiesterase-5 inhibitor (PDE5) drugs work using a process of vasodilation, and most are considered to be slow-acting, <a href="https://pr.report/hz2rmoHT">requiring 1-2 hours</a> to reach peak levels in the bloodstream for maximum effectiveness. Lexaria has repeatedly evidenced a greatly reduced delivery time of another drug that encourages vasodilation - DehydraTECH CBD - and theorizes whether DehydraTECH might likewise deliver PDE5 drugs more quickly and effectively. Some of the most popular existing erectile dysfunction drugs have seen their primary patents expire. DehydraTECH for PDE5 drugs is patent pending.</p><br /> <br /> <p>All scheduling is subject to change, postponement, or even cancellation, but as of the date of this press release are reasonable expectations. All studies referenced within this press release are fully funded from existing Company resources and are being performed by third-party laboratories to ensure study objectivity.</p><br /> <br /> <p><b>About Lexaria Bioscience Corp.</b></p><br /> <br /> <p>Lexaria Bioscience Corp.'s proprietary drug delivery technology, DehydraTECH™, improves the way active pharmaceutical ingredients (APIs) enter the bloodstream by promoting healthier oral ingestion methods and increasing the effectiveness of fat-soluble active molecules, thereby lowering overall dosing. The Company's technology can be applied to many different ingestible product formats, including foods, beverages, oral suspensions, tablets, and capsules. DehydraTECH has repeatedly demonstrated since 2016 with cannabinoids and nicotine the ability to increase bio-absorption by up to 5-10x, reduce time of onset from 1 - 2 hours to minutes, and mask unwanted tastes; and is planned to be further evaluated for orally administered bioactive molecules, including anti-virals, cannabinoids, vitamins, non-steroidal anti-inflammatory drugs (NSAIDs), and nicotine. Lexaria has licensed DehydraTECH to multiple companies, including a world-leading tobacco producer for the development of smokeless, oral-based nicotine products and for use in industries that produce cannabinoid beverages, edibles, and oral products. Lexaria operates a licensed in-house research laboratory and holds a robust intellectual property portfolio with 18 patents granted and approximately 60 patents pending worldwide. For more information, please visit <a href="https://pr.report/OwhyHg3N">www.lexariabioscience.com</a>.</p><br /> <br /> <p><b>CAUTION REGARDING FORWARD-LOOKING STATEMENTS</b></p><br /> <br /> <p>This press release includes forward-looking statements. Statements as such term is defined under applicable securities laws. These statements may be identified by words such as "anticipate," "if," "believe," "plan," "estimate," "expect," "intend," "may," "could," "should," "will," and other similar expressions. Such forward-looking statements in this press release include, but are not limited to, statements by the company relating the Company's ability to carry out research initiatives, receive regulatory approvals or grants, or experience positive effects or results from any research or study. Such forward-looking statements are estimates reflecting the Company's best judgment based upon current information and involve a number of risks and uncertainties, and there can be no assurance that the Company will actually achieve the plans, intentions, or expectations disclosed in these forward-looking statements. As such, you should not place undue reliance on these forward-looking statements. Factors which could cause actual results to differ materially from those estimated by the Company include, but are not limited to, government regulation and regulatory approvals, managing and maintaining growth, the effect of adverse publicity, litigation, competition, scientific discovery, the patent application, and approval process, potential adverse effects arising from the testing or use of products utilizing the DehydraTECH technology, the Company's ability to maintain existing collaborations and realize the benefits thereof, delays or cancellations of planned R&D that could occur related to pandemics or for other reasons, and other factors which may be identified from time to time in the Company's public announcements and periodic filings with the US Securities and Exchange Commission on EDGAR. There is no assurance that any of Lexaria's postulated uses, benefits, or advantages for the patented and patent-pending technology will, in fact, be realized in any manner or in any part. No statement herein has been evaluated by the Food and Drug Administration (FDA). Lexaria-associated products are not intended to diagnose, treat, cure or prevent any disease. Any forward-looking statements contained in this release speak only as of the date hereof, and the Company expressly disclaims any obligation to update any forward-looking statements contained herein, whether as a result of any new information, future events, changed circumstances, or otherwise, except as otherwise required by law.</p><br /> <br /> <p><i>The CSE has not reviewed and does not accept responsibility for the adequacy or accuracy of this release.</i></p><br /> <br /> <p><b>INVESTOR CONTACT:</b></p><br /> <br /> <p><a href="/cdn-cgi/l/email-protection#8ce5fecce0e9f4edfee5edeee5e3ffefe5e9e2efe9a2efe3e1"><span class="__cf_email__" data-cfemail="d7bea597bbb2afb6a5beb6b5beb8a4b4beb2b9b4b2f9b4b8ba">[email protected]</span></a><br><br /> Phone: 866-221-3341</p><br /> <br /> <p><strong>SOURCE: </strong>Lexaria Bioscience Corp.</p><br /> <br><br>View source version on accesswire.com: <br><a href='https://www.accesswire.com/639012/Lexaria-to-Evaluate-DehydraTECHTM-in-Multiple-New-Markets'>https://www.accesswire.com/639012/Lexaria-to-Evaluate-DehydraTECHTM-in-Multiple-New-Markets</a><br><br><img src='https://www.accesswire.com/img.ashx?id=639012' /></div></div> <div class="themestek-blog-classic-footer-readmore"> <div class="themestek-blogbox-footer-left"><a href="https://lexariabioscience.com/2021/04/06/lexaria-to-evaluate-dehydratechtm-in-multiple-new-markets/">Read More</a></div> </div> <div class="ts-footer-meta-wrapper"> <span class="ts-footer-meta-line-w ts-footer-meta-line-comments"> <a href="https://lexariabioscience.com/2021/04/06/lexaria-to-evaluate-dehydratechtm-in-multiple-new-markets/"> <i class="ts-labtechco-icon-comment-1"></i> <span class="comments"> 0 Comments </span> </a> </span> <span class="ts-footer-meta-line-w ts-footer-meta-line-author"> <span class="author vcard"> <span class="screen-reader-text ts-hide">Author </span> <a class="url fn n" 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