Neuroscience - Chan Zuckerberg Initiative

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class="container--global-search"> <div class="container--search-items"> <form class="search" method="get" action="https://chanzuckerberg.com" role="search" > <div class="search-icon"> <svg xmlns="http://www.w3.org/2000/svg" width="23" height="23" viewBox="0 0 23 23" fill="none" > <style> .c { stroke-width: 2; stroke: #ff414b; } </style> <path d="M15.5 15.7L21.4 21.6" class="c" /> <path d="M9.7 18.1C14.2 18.1 17.9 14.4 17.9 9.9 17.9 5.3 14.2 1.6 9.7 1.6 5.1 1.6 1.4 5.3 1.4 9.9 1.4 14.4 5.1 18.1 9.7 18.1Z" class="c" /> </svg> </div> <input class="search--textfield" type="text" name="s" id="search" value="" placeholder="Search" aria-label="Search" /> <button type="submit"> <div class="button-cta__arrow cta-arrow cta-arrow--red "> <div class="cta-arrow__bkg"></div> </div> </button> </form> <div class="close-icon"> <svg xmlns="http://www.w3.org/2000/svg" width="44" height="44" viewBox="0 0 44 44" fill="none" > <style> .b { stroke-width: 2; stroke: black; } </style> <circle cx="22" cy="22" r="22" fill="#FAFAFA" /> <g opacity="0.8"> <path d="M15.1 14.9L29.2 29.1" class="b" /> <path d="M15.1 29.1L29.2 14.9" class="b" /> </g> </svg> </div> </div> </div> </div> </header> <main id="content" role="main" class="content-wrapper with-subnav ">  <div class="search-overlay "></div> <div class="dimmed-overlay"></div> <section class="section--hero hero"> <div class="hero__wrapper section--border-bottom"> <div class="hero__bkg"></div> <div class="hero__block"> <h1 class="hero__title t-h2--bold color--red">Neuroscience</h1> <div class="t-body--large section--border-txt-left"> <p>The Neuroscience program was launched in 2018 with a focus on neurodegenerative disease and centered on the <a href="/science/programs-resources/neurodegeneration-challenge/">CZI Neurodegeneration Challenge Network (NDCN)</a>. The Challenge Network model is built on the vision that progress in solving neurodegenerative diseases will come from bringing new talent and ideas from diverse disciplines and expertise into the neurodegeneration field, building interdisciplinary collaborations, empowering the broader scientific community with robust tools and platforms, and creating a culture of innovation, collaboration, and open science.</p> <p>Building on learnings and successes of the Challenge Network model, we have expanded the focus of our program from neurodegeneration to other areas of fundamental neuroscience. In addition to our ongoing focus on mechanisms of neurodegeneration, new grantees will broaden our remit to include research in areas such as cellular neuroscience, sleep biology, and circuit mechanisms for learning, memory & cognition.</p> </div> </div> </div> <div class="hero__wrapper section--border-bottom"> <div class="hero__block--img"> <div class="hero__image hero__image--2-3-first frame frame--red"> <div class="fit-photo fit-photo "> <img src="https://chanzuckerberg.com/wp-content/uploads/2024/04/sun1-gfp-neuronal-nuclei-angel-barco-guerrero.png" alt="DNA (blue), a nucleosome histone modification (in red) and the nuclear envelope (protein SUN1 fused to GFP in green) generated by super-resolution fluorescence microscopy (Airyscan technology)." object-fit-polyfill loading="lazy" /> <div class="caption--overlay t-caption "></div> <figcaption class="caption t-caption "> Labeling of neuronal nuclei in the adult mouse hippocampus. Photo by CZI Neuroscience grantee Angel Barco.</figcaption> </div> <div class="caption--overlay t-caption is-left color--white "></div> <figcaption class="caption t-caption is-left color--white "> Labeling of neuronal nuclei in the adult mouse hippocampus. Photo by CZI Neuroscience grantee Angel Barco.</figcaption> </div> </div> </div> <div class="funded-module"> <div class="funded-module--title"> <h6 class="t-h6--semibold">The Neuroscience program has funded the following RFAs:</h6> </div> <div class="funded-module--col"> <div class="funded-module--col-left"> <div class="funded-module--col-left-content"> <ul> <li><a href="https://chanzuckerberg.com/science/programs-resources/neurodegeneration-challenge/projects/?award=collaborative-science">Collaborative Science Awards</a>, $9.5 million</li> <li><a href="https://chanzuckerberg.com/patient-partnered-collaborations-for-rare-neurodegenerative-disease-rfa-grantees/">Patient-Partnered Collaborations for Rare Neurodegenerative Disease</a>, $10 million</li> <li>Ben Barres Award Early Career Acceleration Awards (<a href="https://chanzuckerberg.com/science/programs-resources/neurodegeneration-challenge/projects/?award=ben-barres-early-career-acceleration">Cycle 1</a>, $42.5 million and <a href="https://chanzuckerberg.com/science/programs-resources/neurodegeneration-challenge/projects/?award=ben-barres-cycle-2">Cycle 2</a>, $15.6 million)</li> <li>Collaborative Pairs Pilot Project Awards (Cycle 1 (<a href="https://chanzuckerberg.com/science/programs-resources/neurodegeneration-challenge/projects/?award=collaborative-pairs-pilot-project">Phase 1</a>, which is inclusive of all grants, and <a href="https://chanzuckerberg.com/science/programs-resources/neurodegeneration-challenge/projects/?award=collaborative-pairs-pilot-project-phase-2">Phase 2</a>), $30.1 million and <a href="https://chanzuckerberg.com/science/programs-resources/neurodegeneration-challenge/projects/?award=collaborative-pairs-pilot-project-cycle-2-phase-1">Cycle 2</a>, <span style="font-weight: 400">$12.8 million</span>)</li> </ul> </div> </div> <div class="funded-module--col-right"> <div class="funded-module--col-right-content"> <a href="https://chanzuckerberg.com/science/programs-resources/neurodegeneration-challenge/projects/" class="learn-more-container"> <div class="learn-more-container__img"> <img src="https://chanzuckerberg.com/wp-content/uploads/2020/06/grantees.png" alt="Stylized "Learn About Our Grantees" icon of two interconnected figures beneath a diagonal ascending arrow (CZI Neurodegeneration Challenge Network, NDCN)."> </div> <div class="learn-more-container__text"> <p class="t-h6--semibold color--black">Meet the grantees</p> <div class="t-smallcaps-plain--small color--red">Learn More</div> <svg width="20" height="9" fill="none" xmlns="http://www.w3.org/2000/svg"><path d="M13.826 8.333V0l6 4.167-6 4.166z" fill="#FF414B"/><path d="M15.651 4.167H1" stroke="#000" stroke-linecap="square"/></svg> </div> </a> </div> </div> </div> </div> <div class="hero__wrapper section--border-bottom has-padding-l-3"> <div class="hero__block hero__block--img"> <div class="hero__image hero__image--2-3-second frame frame--red"> <div class="fit-photo fit-photo "> <img src="https://chanzuckerberg.com/wp-content/uploads/2024/04/ndcn-annual-meeting-2023.png" alt="Two women stand together, smiling at the camera, at the 2023 NDCN Annual Meeting" object-fit-polyfill loading="lazy" /> <div class="caption--overlay t-caption "></div> <figcaption class="caption t-caption "> Members of the Neurodegeneration Challenge Network at the 2023 Annual Meeting</figcaption> </div> <div class="caption--overlay t-caption is-left color--white "></div> <figcaption class="caption t-caption is-left color--white "> Members of the Neurodegeneration Challenge Network at the 2023 Annual Meeting</figcaption> </div> </div> </div> <div class="hero__wrapper section--border-bottom"> <div class="hero__block hero__block--txt"> <div class="hero__p t-h5--roman"> <h3 class="hero__title color--red t-h3--bold">The Neurodegeneration Challenge Network</h3> <div class="t-body--large"> <p>The CZI Neurodegeneration Challenge Network (NDCN) brings together experimental scientists from diverse research fields, along with computational biologists and physicians, to understand the fundamental biology of neurodegenerative disorders. Their shared aim is to develop new strategies for the treatment and prevention of neurodegenerative disease.</p> </div> </div> <a href="https://chanzuckerberg.com/science/programs-resources/neurodegeneration-challenge/" class="button-cta button-cta--"> <div class="button-cta__text">Learn About the NDCN</div> <div class="button-cta__arrow cta-arrow cta-arrow--red"> <div class="cta-arrow__bkg"></div> </div> </a> </div> </div> </section> <section class="section--cards-grid section--border-bottom-100vw section--border-bottom-margin-1 section--padding-b-1 section--border-bottom-mobile-hidden carousel cards-grid--carousel " carousel-container data-number-moving="1" data-stop-offset-mobile="0" data-stop-offset="0" mobile-only id="" > <header class="cards-grid--related__header header__column"> <h2 class="t-h3--semibold color--red">Funding Opportunities </h2> </header> <div class="carousel__slider section-- " carousel-slider> <div class="cards-section cards-section--carousel cards-section--3-cols section--"> <div class="card rfa-card list__row is-active" carousel-item card> <div class="card__wrapper"> <a href="https://chanzuckerberg.com/rfa/ndcn-collaborative-pairs/" class="card__link" title="Visit Collaborative Pairs Pilot Project Awards (Cycle 2)" aria-labelledby="card-title-6358"></a> <div class="card__pattern background--pink"> <svg viewBox="0 0 315 315" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><clipPath id="a"><path d="m0 0h315v315h-315z"/></clipPath><g style="clip-path:url(#a);opacity:0.35;fill:none;stroke:black;stroke-linecap:round;stroke-miterlimit:10"><rect height="470.02" rx="235.01" transform="matrix(.70710678 -.70710678 .70710678 .70710678 -65.24 157.5)" width="470.02" x="-77.51" y="-77.51"/><rect height="443.68" rx="221.84" transform="matrix(.70710678 -.70710678 .70710678 .70710678 -65.24 157.5)" width="443.68" x="-64.34" y="-64.34"/><rect height="417.34" rx="208.67" transform="matrix(.70710678 -.70710678 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fields of neurodegenerative diseases and fundamental neuroscience. </p> <div class="card__footer"> <ul class="card__infos"> <li> <span class="card__info__title color--red t-body--x-small">Cycle 2 - </span> <span class="card__info__desc t-body--x-small td-searchable">$12.8 million</span> </li> <div class="card__info__divider"></div> <button class="card__info__view-all t-body--x-small color--red"> <span>All grant resources</span> <svg width="21" height="9" viewBox="0 0 21 9" fill="none" xmlns="http://www.w3.org/2000/svg"> <path d="M14.1433 8.91669L14.1433 0.583354L20.1433 4.75002L14.1433 8.91669Z" fill="#FF414B"/> <path d="M15.9688 4.75L1.31763 4.75" stroke="black" stroke-linecap="square"/> </svg> </button> </ul> <a href="https://chanzuckerberg.com/rfa/ndcn-collaborative-pairs/" target="_self" class="button-cta button-cta-- button-cta-- " title="Visit Collaborative Pairs Pilot Project Awards (Cycle 2) page" aria-label="" > <div class="button-cta__text " >RFA details</div> <div class="button-cta__arrow cta-arrow cta-arrow--red "> <div class="cta-arrow__bkg"></div> </div> </a> </div> <div class="card__all-resources"> <div class="card__resources-close"> <svg width="31" height="32" viewBox="0 0 31 32" fill="none" xmlns="http://www.w3.org/2000/svg"> <path opacity="0.6" d="M20.8023 10.4473L10.1973 21.0523M20.8023 21.0523L10.1973 10.4473M15.5 30.75C23.7843 30.75 30.5 24.0343 30.5 15.75C30.5 7.46573 23.7843 0.75 15.5 0.75C7.21573 0.75 0.5 7.46573 0.5 15.75C0.5 24.0343 7.21573 30.75 15.5 30.75Z" stroke="black" stroke-linecap="round" stroke-linejoin="round"/> </svg> </div> <div class="card__resources-title t-smallcaps-plain--small">Collaborative Pairs Pilot Project Awards </div> <div class="card__info__divider"></div> <ul class="card__infos"> <li> <span class="card__info__title color--red t-body--x-small"> <a href="https://chanzuckerberg.com/science/programs-resources/neurodegeneration-challenge/projects/?award=collaborative-pairs-pilot-project,collaborative-pairs-pilot-project-phase-2"> Cycle 1 </a> </span> <span class="card__info__desc t-body--x-small td-searchable"> - $30.1 Million</span> </li> <li> <span class="card__info__title color--red t-body--x-small"> <a href="https://chanzuckerberg.com/science/programs-resources/neurodegeneration-challenge/projects/?award=collaborative-pairs-pilot-project-cycle-2-phase-1"> Cycle 2 </a> </span> <span class="card__info__desc t-body--x-small td-searchable"> - $12.8 million</span> </li> </ul> </div> </div> </div> </div> <div class="card rfa-card list__row is-active" carousel-item card> <div class="card__wrapper"> <a href="https://chanzuckerberg.com/rfa/ben-barres-early-career-acceleration-awards/" class="card__link" title="Visit Ben Barres Early Career Acceleration Awards (Cycles 1-2)" target="_blank" aria-labelledby="card-title-453"></a> <div class="card__pattern background--pink"> <svg viewBox="0 0 315 315" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><clipPath id="a"><path d="m0 0h315v315h-315z"/></clipPath><g style="clip-path:url(#a);opacity:0.35;fill:none;stroke:black;stroke-linecap:round;stroke-miterlimit:10"><path d="m-77.51-77.51h470.02v470.02h-470.02z" transform="matrix(.70710678 -.70710678 .70710678 .70710678 -65.24 157.5)"/><path d="m-64.34-64.34h443.68v443.68h-443.68z" transform="matrix(.70710678 -.70710678 .70710678 .70710678 -65.24 157.5)"/><path d="m-51.17-51.17h417.34v417.34h-417.34z" transform="matrix(.70710678 -.70710678 .70710678 .70710678 -65.24 157.5)"/><path d="m-38-38h390.99v390.99h-390.99z" transform="matrix(.70710678 -.70710678 .70710678 .70710678 -65.24 157.5)"/><path d="m-24.83-24.83h364.65v364.65h-364.65z" transform="matrix(.70710678 -.70710678 .70710678 .70710678 -65.24 157.5)"/><path d="m-11.66-11.66h338.31v338.31h-338.31z" transform="matrix(.70710678 -.70710678 .70710678 .70710678 -65.24 157.5)"/><path d="m1.51 1.51h311.97v311.97h-311.97z" transform="matrix(.70710678 -.70710678 .70710678 .70710678 -65.24 157.5)"/><path d="m14.68 14.68h285.63v285.63h-285.63z" transform="matrix(.70710678 -.70710678 .70710678 .70710678 -65.24 157.5)"/><path d="m27.86 27.86h259.29v259.29h-259.29z" transform="matrix(.70710678 -.70710678 .70710678 .70710678 -65.24 157.5)"/><path d="m41.03 41.03h232.95v232.95h-232.95z" transform="matrix(.70710678 -.70710678 .70710678 .70710678 -65.24 157.5)"/><path d="m54.2 54.2h206.61v206.61h-206.61z" transform="matrix(.70710678 -.70710678 .70710678 .70710678 -65.24 157.5)"/><path d="m67.37 67.37h180.27v180.27h-180.27z" transform="matrix(.70710678 -.70710678 .70710678 .70710678 -65.24 157.5)"/><path d="m80.54 80.54h153.93v153.93h-153.93z" transform="matrix(.70710678 -.70710678 .70710678 .70710678 -65.24 157.5)"/><path d="m93.71 93.71h127.58v127.58h-127.58z" transform="matrix(.70710678 -.70710678 .70710678 .70710678 -65.24 157.5)"/><path d="m106.88 106.88h101.24v101.24h-101.24z" transform="matrix(.70710678 -.70710678 .70710678 .70710678 -65.24 157.5)"/><path d="m120.05 120.05h74.9v74.9h-74.9z" transform="matrix(.70710678 -.70710678 .70710678 .70710678 -65.24 157.5)"/><path d="m133.22 133.22h48.56v48.56h-48.56z" transform="matrix(.70710678 -.70710678 .70710678 .70710678 -65.24 157.5)"/><path d="m146.39 146.39h22.22v22.22h-22.22z" transform="matrix(.70710678 -.70710678 .70710678 .70710678 -65.24 157.5)"/></g></svg> </div> <div class="card__background background--off-gray"></div> <div class="card__container"> <div class="card__alert t-smallcaps-plain--large background--gray-dark">Closed</div> <div class="card__header"> <h5 class="card__surtitle t-smallcaps-plain--small color--red">Request for Applications</h5> <h5 class="card__surtitle t-smallcaps-plain--small color--off-black td-searchable">Neurodegeneration Challenge Network</h5> <h4 class="card__title t-h5--semibold td-searchable" id="card-title-453">Ben Barres Early Career Acceleration Awards (Cycles 1-2)</h4> </div> <p class="card__text t-body--x-small td-searchable"> This RFA aims to provide mentored support for early career investigators to conduct bold, innovative, and rigorous research in the basic science underlying neurodegenerative disease and fundamental neuroscience. </p> <div class="card__footer"> <ul class="card__infos"> <li> <span class="card__info__title color--red t-body--x-small">Cycle 2 - </span> <span class="card__info__desc t-body--x-small td-searchable">$15.6 Million</span> </li> <div class="card__info__divider"></div> <button class="card__info__view-all t-body--x-small color--red"> <span>All grant resources</span> <svg width="21" height="9" viewBox="0 0 21 9" fill="none" xmlns="http://www.w3.org/2000/svg"> <path d="M14.1433 8.91669L14.1433 0.583354L20.1433 4.75002L14.1433 8.91669Z" fill="#FF414B"/> <path d="M15.9688 4.75L1.31763 4.75" stroke="black" stroke-linecap="square"/> </svg> </button> </ul> <a href="https://chanzuckerberg.com/rfa/ben-barres-early-career-acceleration-awards/" target="_blank" class="button-cta button-cta-- button-cta-- " title="Visit Ben Barres Early Career Acceleration Awards (Cycles 1-2) page (Opens a new window)" aria-label="" > <div class="button-cta__text " >RFA Details</div> <div class="button-cta__arrow cta-arrow cta-arrow--red "> <div class="cta-arrow__bkg"></div> </div> </a> </div> <div class="card__all-resources"> <div class="card__resources-close"> <svg width="31" height="32" viewBox="0 0 31 32" fill="none" xmlns="http://www.w3.org/2000/svg"> <path opacity="0.6" d="M20.8023 10.4473L10.1973 21.0523M20.8023 21.0523L10.1973 10.4473M15.5 30.75C23.7843 30.75 30.5 24.0343 30.5 15.75C30.5 7.46573 23.7843 0.75 15.5 0.75C7.21573 0.75 0.5 7.46573 0.5 15.75C0.5 24.0343 7.21573 30.75 15.5 30.75Z" stroke="black" stroke-linecap="round" stroke-linejoin="round"/> </svg> </div> <div class="card__resources-title t-smallcaps-plain--small">Ben Barres Early Career Acceleration Awards </div> <div class="card__info__divider"></div> <ul class="card__infos"> <li> <span class="card__info__title color--red t-body--x-small"> <a href="https://chanzuckerberg.com/science/programs-resources/neurodegeneration-challenge/projects/?award=ben-barres-early-career-acceleration"> Cycle 1 </a> </span> <span class="card__info__desc t-body--x-small td-searchable"> - $42.5 Million</span> </li> <li> <span class="card__info__title color--red t-body--x-small"> <a href="https://chanzuckerberg.com/science/programs-resources/neurodegeneration-challenge/projects/?award=ben-barres-cycle-2"> Cycle 2 </a> </span> <span class="card__info__desc t-body--x-small td-searchable"> - $15.6 Million</span> </li> </ul> </div> </div> </div> </div> <div class="card rfa-card list__row is-active" carousel-item card> <div class="card__wrapper"> <a href="https://chanzuckerberg.com/rfa/patient-partnered-collaborations-ppc-for-rare-neurodegenerative-disease/" class="card__link" title="Visit 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y="146.39"/></g></svg> </div> <div class="card__background background--off-gray"></div> <div class="card__container"> <div class="card__alert t-smallcaps-plain--large background--gray-dark">Closed</div> <div class="card__header"> <h5 class="card__surtitle t-smallcaps-plain--small color--red">Request for Applications</h5> <h5 class="card__surtitle t-smallcaps-plain--small color--off-black td-searchable">Neurodegeneration Challenge Network</h5> <h4 class="card__title t-h5--semibold td-searchable" id="card-title-21192">Patient-Partnered Rare Neurodegenerative Disease RFA</h4> </div> <p class="card__text t-body--x-small td-searchable"> This RFA aims to advance the understanding of the pathophysiology and mechanistic underpinnings of rare neurodegenerative and neurological disorders. </p> <div class="card__footer"> <ul class="card__infos"> <li> <span class="card__info__title color--red t-body--x-small">Total Grant Resources </span> <span class="card__info__desc t-body--x-small td-searchable">$10 Million</span> </li> </ul> <a href="https://chanzuckerberg.com/rfa/patient-partnered-collaborations-ppc-for-rare-neurodegenerative-disease/" target="_self" class="button-cta button-cta-- button-cta-- " title="Visit Patient-Partnered Rare Neurodegenerative Disease RFA page" aria-label="" > <div class="button-cta__text " >RFA Details</div> <div class="button-cta__arrow cta-arrow cta-arrow--red "> <div class="cta-arrow__bkg"></div> </div> </a> </div> </div> </div> </div> </div> <div class="cards-section cards-section--carousel cards-section--3-cols section--border-top"> <div class="card rfa-card list__row is-active" carousel-item card> <div class="card__wrapper"> <a href="https://chanzuckerberg.com/rfa/collaborative-science-awards/" class="card__link" title="Visit Collaborative Science Awards" aria-labelledby="card-title-454"></a> <div class="card__pattern background--teal"> <svg viewBox="0 0 315 315" xmlns="http://www.w3.org/2000/svg" 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td-searchable"> <span class="mobile-only">As part of the CZI Neurodegeneration Challenge Network, an interdisciplinary collaborative network that addresses fundamental issues in neurodegenerative disease biology, these are grant opportunities for small group interdisciplinary research collaborations tha</span><span class="ellipsis-dots mobile-only">...</span> <span class="desktop-only">As part of the CZI Neurodegeneration Challenge Network, an interdisciplinary collaborative network that addresses fundamental issues in neurodegenerative disease biology, these are grant opportunities for small group interdisciplinary research collaborations that include a physician with active clinical engagement. </span> </p> <div class="card__footer"> <ul class="card__infos"> <li> <span class="card__info__title color--red t-body--x-small">Total Grant Resources </span> <span class="card__info__desc t-body--x-small td-searchable">$9 Million</span> </li> </ul> <a href="https://chanzuckerberg.com/rfa/collaborative-science-awards/" target="_self" class="button-cta button-cta-- button-cta-- " title="Visit Collaborative Science Awards page" aria-label="" > <div class="button-cta__text " >RFA Details</div> <div class="button-cta__arrow cta-arrow cta-arrow--red "> <div class="cta-arrow__bkg"></div> </div> </a> </div> </div> </div> </div> </div> </div> <footer class="carousel__footer"> <div class="carousel__buttons" carousel-controls> <button tabindex="-1" class="button-carousel button-prev" aria-label="prev" carousel-prev><div class="cta-arrow"></div></button> <button tabindex="-1" class="button-carousel button-next" aria-label="next" carousel-next><div class="cta-arrow"></div></button> </div> <span class="carousel__index-number"><span carousel-active-index></span> / 4</span> </footer> </section> <section class="section--cards-grid section-- carousel cards-grid--carousel cards-grid--latest cards-grid--highlights-carousel" carousel-container 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Get the latest information from the links below.</p> </header> <div class="carousel__slider highlights-carousel section-- " carousel-slider> <div class="cards-section cards-section--latest cards-section--3-cols section--"> <div class="card background-image-card card--align-top card--align-center card--button-bottom list__row is-active" carousel-item card> <div class="card__wrapper"> <a href="https://chanzuckerberg.com/blog/2024-look-back/" class="card__link" title="Read Story - How AI Shaped a Year of Impact at CZI" aria-labelledby="card-title-33455"></a> <div class="card__background "> <div class="fit-photo fit-photo "> <picture> <source media="(max-width: 768px)" srcset="https://chanzuckerberg.com/wp-content/uploads/2024/12/24_1209-CZI-EOY-Moments-Mobile-BLANK.jpg"> <source media="(min-width: 769px)" srcset="https://chanzuckerberg.com/wp-content/uploads/2024/12/24_1209-CZI-EOY-Moments-Desktop-BLANK.jpg"> <img src="https://chanzuckerberg.com/wp-content/uploads/2024/12/24_1209-CZI-EOY-Moments-Desktop-BLANK.jpg" alt="A collage of moments featuring circular cutouts of Sandra Liu Huang in a classroom, researchers in a lab, a close-up of a gloved hand holding a tiny device, Priscilla Chan and Mark Zuckerberg clapping on stage, and Patricia Brennan and Theofanis Karaletsos in a keynote, all set against a vibrant red background with colorful abstract designs." object-fit-polyfill loading="lazy" /> </picture> </div> </div> <div class="card__container"> <div class="card__surtitle t-category-label background--green color--white">2024 Look Back</div> <div class="card__title t-h4--bold color--white" id="card-title-33455">How AI Shaped a Year of Impact at CZI</div> <a href="https://chanzuckerberg.com/blog/2024-look-back/" target="_self" class="button-cta button-cta-- button-cta--light-fill " title="Read Story" aria-label="" > <div class="button-cta__text " >Read Story</div> <div class="button-cta__arrow cta-arrow cta-arrow--red "> <div class="cta-arrow__bkg"></div> </div> </a> </div> </div> </div> <div class="card background-image-card card--align-top card--align-center card--button-bottom list__row is-active" carousel-item card> <div class="card__wrapper"> <a href="https://chanzuckerberg.com/blog/2023-look-back/" class="card__link" title="Explore Story - 7 Memorable Moments & Learnings From Across Our Work" aria-labelledby="card-title-29869"></a> <div class="card__background "> <div class="fit-photo fit-photo "> <picture> <source media="(max-width: 768px)" srcset="https://chanzuckerberg.com/wp-content/uploads/2023/12/23_1130-CZI-7-Memorable-Moments-2023-Mobile-BLANK.jpg"> <source media="(min-width: 769px)" srcset="https://chanzuckerberg.com/wp-content/uploads/2023/12/23_1130-CZI-7-Memorable-Moments-2023-Desktop-BLANK.jpg"> <img src="https://chanzuckerberg.com/wp-content/uploads/2023/12/23_1130-CZI-7-Memorable-Moments-2023-Desktop-BLANK.jpg" alt="Four circular images related to CZI’s work in science, education and California’s Bay Area community on a blue gradient background. 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A Scientist’s Groundbreaking ALS Discovery" aria-labelledby="card-title-23443"></a> <div class="card__background "> <div class="fit-photo fit-photo "> <picture> <source media="(max-width: 768px)" srcset="https://chanzuckerberg.com/wp-content/uploads/2022/07/22_0712-CZI-HP-Groundbreaking-ALS-Discovery-Mobile-BLANK.jpg"> <source media="(min-width: 769px)" srcset="https://chanzuckerberg.com/wp-content/uploads/2022/07/22_0712-CZI-HP-Groundbreaking-ALS-Discovery-Desktop-BLANK.jpg"> <img src="https://chanzuckerberg.com/wp-content/uploads/2022/07/22_0712-CZI-HP-Groundbreaking-ALS-Discovery-Desktop-BLANK.jpg" alt="Illustration of Ivan Marazzi in discussion with a colleague" object-fit-polyfill loading="lazy" /> </picture> </div> </div> <div class="card__container"> <div class="card__surtitle t-category-label background--green color--white">Science</div> <div class="card__title t-h4--bold color--white" id="card-title-23443">A Scientist’s Groundbreaking ALS Discovery</div> <a href="https://chanzuckerberg.com/blog/ivan-marazzi-als-disease/" target="_self" class="button-cta button-cta-- button-cta--light-fill " title="Explore Photo Story" aria-label="" > <div class="button-cta__text " >Explore Photo Story</div> <div class="button-cta__arrow cta-arrow cta-arrow--red "> <div class="cta-arrow__bkg"></div> </div> </a> </div> </div> </div> <div class="card background-image-card card--align-top card--align-center card--button-bottom list__row is-active" carousel-item card> <div class="card__wrapper"> <a href="https://chanzuckerberg.com/blog/series/collaborative-science/" class="card__link" title="Explore Series - 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