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Peter Sörös | Carl von Ossietzky University of Oldenburg - Academia.edu

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class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/104382968/Diffusion_tensor_imaging_of_white_matter_microstructure_in_chronic_pain_a_tract_based_spatial_statistics_study_and_a_systematic_review"><img alt="Research paper thumbnail of Diffusion tensor imaging of white matter microstructure in chronic pain: a tract-based spatial statistics study and a systematic review" class="work-thumbnail" src="https://attachments.academia-assets.com/104128402/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/104382968/Diffusion_tensor_imaging_of_white_matter_microstructure_in_chronic_pain_a_tract_based_spatial_statistics_study_and_a_systematic_review">Diffusion tensor imaging of white matter microstructure in chronic pain: a tract-based spatial statistics study and a systematic review</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The pathophysiology of many chronic pain disorders is far from evident. MR imaging studies provid...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The pathophysiology of many chronic pain disorders is far from evident. MR imaging studies provided initial data indicating chronic pain might lead to changes in brain structure and function. These changes may contribute to cognitive and emotional impairment and maybe even to the chronification of pain. However, the evidence for pain-related changes in gray and white matter is inconclusive so far. Hence we investigated potential changes of white matter microstructure in 34 adults with chronic noncancer pain (&amp;gt; 1 year) and 34 sex- and age-matched healthy individuals using diffusion tensor imaging (DTI). Whole-brain tract-based spatial statistics (TBSS) analyses of fractional anisotropy, mode of diffusivity, mean diffusivity, axial diffusivity, and radial diffusivity did not show significant differences after correction for multiple comparisons. The volumes of subdivisons of the corpus callosum were not significantly different either. We also performed a systematic review of the ex...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="eb56a01c28a1e84d85fad68262e999e2" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:104128402,&quot;asset_id&quot;:104382968,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/104128402/download_file?st=MTczMjQwOTc1NCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="104382968"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="104382968"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 104382968; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=104382968]").text(description); $(".js-view-count[data-work-id=104382968]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 104382968; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='104382968']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 104382968, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "eb56a01c28a1e84d85fad68262e999e2" } } $('.js-work-strip[data-work-id=104382968]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":104382968,"title":"Diffusion tensor imaging of white matter microstructure in chronic pain: a tract-based spatial statistics study and a systematic review","translated_title":"","metadata":{"abstract":"The pathophysiology of many chronic pain disorders is far from evident. 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The aims of the present study were twofold: using task-based functional MRI in a group of 17 healthy young participants, we studied (1) potential differences in the cerebral control of frontal, horizontal, and vertical tongue movements and (2) potential inter-individual differences in tongue motor control. To investigate differences between different tongue movements, we performed voxel-wise multiple linear regressions. To investigate inter-individual differences, we applied a novel approach, spatio-temporal filtering of independent components. For this approach, individual functional data sets were decomposed into spatially independent components and corresponding time courses using ICA. A temporal filter (correlation with the expected brain response) was used to identify independent components time-locked to the tongue motor task. 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Several lines of evidence support the idea that ADHD is, in its core, a disorder of dysfunctional brain connectivity within and between several neurofunctional networks. The primary aim of this study was to investigate associations between the functional connectivity within resting state brain networks and the individual severity of core ADHD symptoms (inattention, hyperactivity, and impulsivity). Methods: Resting state functional magnetic resonance imaging (rs-fMRI) data of 38 methylphenidate-naïve adults with childhood-onset ADHD (20 women, mean age 40.5 years) were analyzed using independent component analysis (FSL's MELODIC) and FSL's dual regression technique. For motion correction, standard volume-realignment followed by independent component analysis-based automatic removal of motion artifacts (FSL's ICA-AROMA) were employed. To identify well-established brain networks, the independent components found in the ADHD group were correlated with brain networks previously found in healthy participants (Smith et al. PNAS 2009;106:13040-5). To investigate associations between functional connectivity and individual symptom severity, sex, and age, linear regressions were performed. Results: Decomposition of resting state brain activity of adults with ADHD resulted in similar resting state networks as previously described for healthy adults. No significant differences in functional connectivity were seen between women and men. Advanced age was associated with decreased functional connectivity in parts of the bilateral cingulate and paracingulate cortex within the executive control network. More severe hyperactivity was associated with increased functional connectivity in the left putamen, right caudate nucleus, right central operculum and a portion of the right postcentral gyrus within the auditory/sensorimotor network. Conclusions: The present study supports and extends our knowledge on the involvement of the striatum in the pathophysiology of ADHD, in particular, in the pathogenesis of hyperactivity. Our results emphasize the usefulness of dimensional analyses in the study of ADHD, a highly heterogeneous disorder. Trial registration: ISRCTN12722296 (","publication_date":{"day":null,"month":null,"year":2019,"errors":{}},"publication_name":"BMC 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disorder","url":"https://www.academia.edu/Documents/in/Attention_deficit_hyperactivity_disorder-1"}],"urls":[{"id":25141409,"url":"http://link.springer.com/content/pdf/10.1186/s12888-019-2031-9.pdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="89204521"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/89204521/The_Senses_of_Agency_and_Ownership_A_Review"><img alt="Research paper thumbnail of The Senses of Agency and Ownership: A Review" class="work-thumbnail" src="https://attachments.academia-assets.com/93044999/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89204521/The_Senses_of_Agency_and_Ownership_A_Review">The Senses of Agency and Ownership: A Review</a></div><div class="wp-workCard_item"><span>Frontiers in psychology</span><span>, 2018</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Usually, we do not question that we possess a body and act upon the world. This pre-reflective aw...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Usually, we do not question that we possess a body and act upon the world. This pre-reflective awareness of being a bodily and agentive self can, however, be disrupted by different clinical conditions. Whereas sense of ownership (SoO) describes the feeling of mineness toward one&amp;#39;s own body parts, feelings or thoughts, sense of agency (SoA) refers to the experience of initiating and controlling an action. Although SoA and SoO naturally coincide, both experiences can also be made in isolation. By using many different experimental paradigms, both experiences have been extensively studied over the last years. This review introduces both concepts, with a special focus also onto their interplay. First, current experimental paradigms, results and neurocognitive theories about both concepts will be presented and then their clinical and therapeutic relevance is discussed.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="c5935c469a87a84107792be907df1078" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:93044999,&quot;asset_id&quot;:89204521,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/93044999/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="89204521"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="89204521"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 89204521; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=89204521]").text(description); $(".js-view-count[data-work-id=89204521]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 89204521; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='89204521']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 89204521, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "c5935c469a87a84107792be907df1078" } } $('.js-work-strip[data-work-id=89204521]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":89204521,"title":"The Senses of Agency and Ownership: A Review","translated_title":"","metadata":{"abstract":"Usually, we do not question that we possess a body and act upon the world. This pre-reflective awareness of being a bodily and agentive self can, however, be disrupted by different clinical conditions. Whereas sense of ownership (SoO) describes the feeling of mineness toward one\u0026#39;s own body parts, feelings or thoughts, sense of agency (SoA) refers to the experience of initiating and controlling an action. Although SoA and SoO naturally coincide, both experiences can also be made in isolation. By using many different experimental paradigms, both experiences have been extensively studied over the last years. This review introduces both concepts, with a special focus also onto their interplay. First, current experimental paradigms, results and neurocognitive theories about both concepts will be presented and then their clinical and therapeutic relevance is discussed.","publication_date":{"day":null,"month":null,"year":2018,"errors":{}},"publication_name":"Frontiers in psychology"},"translated_abstract":"Usually, we do not question that we possess a body and act upon the world. This pre-reflective awareness of being a bodily and agentive self can, however, be disrupted by different clinical conditions. Whereas sense of ownership (SoO) describes the feeling of mineness toward one\u0026#39;s own body parts, feelings or thoughts, sense of agency (SoA) refers to the experience of initiating and controlling an action. Although SoA and SoO naturally coincide, both experiences can also be made in isolation. By using many different experimental paradigms, both experiences have been extensively studied over the last years. This review introduces both concepts, with a special focus also onto their interplay. First, current experimental paradigms, results and neurocognitive theories about both concepts will be presented and then their clinical and therapeutic relevance is discussed.","internal_url":"https://www.academia.edu/89204521/The_Senses_of_Agency_and_Ownership_A_Review","translated_internal_url":"","created_at":"2022-10-25T10:40:30.287-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":109814020,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":93044999,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93044999/thumbnails/1.jpg","file_name":"aa4cd9dae8d0daa687391242bcc0328c1a93.pdf","download_url":"https://www.academia.edu/attachments/93044999/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"The_Senses_of_Agency_and_Ownership_A_Rev.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93044999/aa4cd9dae8d0daa687391242bcc0328c1a93-libre.pdf?1666723076=\u0026response-content-disposition=attachment%3B+filename%3DThe_Senses_of_Agency_and_Ownership_A_Rev.pdf\u0026Expires=1732413355\u0026Signature=K3TFrOhHychq9-3RpPAUXZgt9sz2BrTcPb-rKxTgdLd-j8yIa-IEiORWbY0hO9V~--HxsG9bjw1NF7ZlRfz9RAEBsmtURNhN1DtgPlEE2h6zTzluafrlbGpe04AmXypIkUNAtm-2N3XqAsH1GiZe5d3h2s66ntnUhHAlS-GRIfkeZHJM9GMaGYXBOsJUMbAYeGYgWH-WCOM38MP8iabLXlmqh6M-sY-oOSnjcJLPtGN5391aUATJDcAwPq5c7ivM8WgFr9LXf8XbGeiurtDl8N5yc6v4CZs0rupce6pE5v5G7ZgjwwSOpONZnv2LgQ01hL1K7oFoP7X3tVFrvCwVLw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"The_Senses_of_Agency_and_Ownership_A_Review","translated_slug":"","page_count":17,"language":"en","content_type":"Work","owner":{"id":109814020,"first_name":"Peter","middle_initials":null,"last_name":"Sörös","page_name":"PeterSörös","domain_name":"uni-oldenburg","created_at":"2019-04-20T13:40:00.221-07:00","display_name":"Peter Sörös","url":"https://uni-oldenburg.academia.edu/PeterS%C3%B6r%C3%B6s"},"attachments":[{"id":93044999,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93044999/thumbnails/1.jpg","file_name":"aa4cd9dae8d0daa687391242bcc0328c1a93.pdf","download_url":"https://www.academia.edu/attachments/93044999/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"The_Senses_of_Agency_and_Ownership_A_Rev.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93044999/aa4cd9dae8d0daa687391242bcc0328c1a93-libre.pdf?1666723076=\u0026response-content-disposition=attachment%3B+filename%3DThe_Senses_of_Agency_and_Ownership_A_Rev.pdf\u0026Expires=1732413355\u0026Signature=K3TFrOhHychq9-3RpPAUXZgt9sz2BrTcPb-rKxTgdLd-j8yIa-IEiORWbY0hO9V~--HxsG9bjw1NF7ZlRfz9RAEBsmtURNhN1DtgPlEE2h6zTzluafrlbGpe04AmXypIkUNAtm-2N3XqAsH1GiZe5d3h2s66ntnUhHAlS-GRIfkeZHJM9GMaGYXBOsJUMbAYeGYgWH-WCOM38MP8iabLXlmqh6M-sY-oOSnjcJLPtGN5391aUATJDcAwPq5c7ivM8WgFr9LXf8XbGeiurtDl8N5yc6v4CZs0rupce6pE5v5G7ZgjwwSOpONZnv2LgQ01hL1K7oFoP7X3tVFrvCwVLw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology"},{"id":817,"name":"Philosophy of Agency","url":"https://www.academia.edu/Documents/in/Philosophy_of_Agency"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":38781,"name":"Sense of agency","url":"https://www.academia.edu/Documents/in/Sense_of_agency"},{"id":51861,"name":"Neurocognitive","url":"https://www.academia.edu/Documents/in/Neurocognitive"},{"id":180133,"name":"Feeling","url":"https://www.academia.edu/Documents/in/Feeling"},{"id":2498386,"name":"Frontiers in Psychology","url":"https://www.academia.edu/Documents/in/Frontiers_in_Psychology"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="89204520"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/89204520/Synthetic_Cannabinoid_Use_in_a_Psychiatric_Patient_Population_A_Pilot_Study"><img alt="Research paper thumbnail of Synthetic Cannabinoid Use in a Psychiatric Patient Population: A Pilot Study" class="work-thumbnail" src="https://attachments.academia-assets.com/93045032/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89204520/Synthetic_Cannabinoid_Use_in_a_Psychiatric_Patient_Population_A_Pilot_Study">Synthetic Cannabinoid Use in a Psychiatric Patient Population: A Pilot Study</a></div><div class="wp-workCard_item"><span>European Addiction Research</span><span>, 2017</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background: Consumption of natural cannabis (NC) and synthetic cannabinoids (SCs) has been associ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background: Consumption of natural cannabis (NC) and synthetic cannabinoids (SCs) has been associated with psychotic disorders. We compared the prevalence of use, consumer profiles, and psychosis-inducing potential of NC and SCs in a specific high-risk population. Methods: This prospective pilot study included 332 patients (18-64 years, mean 36.83, SD 13.33). Patients&amp;#39; sociodemographics and medical histories as well as illicit substance use and psychiatric symptom histories were collected using a drug consumption survey that assessed the use of new psychoactive substances and the Psychotic Symptoms Interview. Results: In total, 7.2% of all patients, 10.6% of psychotic patients, and 4.5% of nonpsychotic patients reported SC consumption. Compared with SCs, NC was consumed much more frequently by its users (mean 222.73, SD 498.27). NC and SC use induced persistent psychosis. Psychotic symptoms were first experienced by patients with a history of NC or SC use during intoxication and...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="5dd295f3be7a560b94be8c79252ca077" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:93045032,&quot;asset_id&quot;:89204520,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/93045032/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="89204520"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="89204520"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 89204520; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=89204520]").text(description); $(".js-view-count[data-work-id=89204520]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 89204520; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='89204520']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 89204520, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "5dd295f3be7a560b94be8c79252ca077" } } $('.js-work-strip[data-work-id=89204520]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":89204520,"title":"Synthetic Cannabinoid Use in a Psychiatric Patient Population: A Pilot Study","translated_title":"","metadata":{"abstract":"Background: Consumption of natural cannabis (NC) and synthetic cannabinoids (SCs) has been associated with psychotic disorders. We compared the prevalence of use, consumer profiles, and psychosis-inducing potential of NC and SCs in a specific high-risk population. Methods: This prospective pilot study included 332 patients (18-64 years, mean 36.83, SD 13.33). Patients\u0026#39; sociodemographics and medical histories as well as illicit substance use and psychiatric symptom histories were collected using a drug consumption survey that assessed the use of new psychoactive substances and the Psychotic Symptoms Interview. Results: In total, 7.2% of all patients, 10.6% of psychotic patients, and 4.5% of nonpsychotic patients reported SC consumption. Compared with SCs, NC was consumed much more frequently by its users (mean 222.73, SD 498.27). NC and SC use induced persistent psychosis. Psychotic symptoms were first experienced by patients with a history of NC or SC use during intoxication and...","publisher":"S. Karger AG","publication_date":{"day":null,"month":null,"year":2017,"errors":{}},"publication_name":"European Addiction Research"},"translated_abstract":"Background: Consumption of natural cannabis (NC) and synthetic cannabinoids (SCs) has been associated with psychotic disorders. We compared the prevalence of use, consumer profiles, and psychosis-inducing potential of NC and SCs in a specific high-risk population. Methods: This prospective pilot study included 332 patients (18-64 years, mean 36.83, SD 13.33). Patients\u0026#39; sociodemographics and medical histories as well as illicit substance use and psychiatric symptom histories were collected using a drug consumption survey that assessed the use of new psychoactive substances and the Psychotic Symptoms Interview. Results: In total, 7.2% of all patients, 10.6% of psychotic patients, and 4.5% of nonpsychotic patients reported SC consumption. Compared with SCs, NC was consumed much more frequently by its users (mean 222.73, SD 498.27). NC and SC use induced persistent psychosis. Psychotic symptoms were first experienced by patients with a history of NC or SC use during intoxication and...","internal_url":"https://www.academia.edu/89204520/Synthetic_Cannabinoid_Use_in_a_Psychiatric_Patient_Population_A_Pilot_Study","translated_internal_url":"","created_at":"2022-10-25T10:40:29.980-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":109814020,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":93045032,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93045032/thumbnails/1.jpg","file_name":"EAR479554.pdf","download_url":"https://www.academia.edu/attachments/93045032/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Synthetic_Cannabinoid_Use_in_a_Psychiatr.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93045032/EAR479554-libre.pdf?1666723070=\u0026response-content-disposition=attachment%3B+filename%3DSynthetic_Cannabinoid_Use_in_a_Psychiatr.pdf\u0026Expires=1732413355\u0026Signature=UyKlgfKOXtjFxydxRha9vKsEKfCx-Gm-b~~XqrTvdmiOH7xoliro~DDvuXERq~QziX5r9ykft5EdkViwWa4NqzChMqt6-AUXxwxMyw2AtBeJ26j9hRuuW2TOz0Zz79uaay2HykKYB6LZuMWWfj23Nbf5VxSYigSPxKqgWx9ybhp-yN1Z641jzvtNDbCGH-q9zBICQSJ2fcPBeiSMsfV7zlur8PuXDZ3nCN2ctHuumoo-NJZNpv8g~jBKWb6QULzO~ghTuNxKgt9EFAulNokSN0DOAnPEnE1XoqdcDnh62jTzyA4GuXf3BwMLBe98zimLJ11qcW69-Zv1JhTaU63m2A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Synthetic_Cannabinoid_Use_in_a_Psychiatric_Patient_Population_A_Pilot_Study","translated_slug":"","page_count":12,"language":"en","content_type":"Work","owner":{"id":109814020,"first_name":"Peter","middle_initials":null,"last_name":"Sörös","page_name":"PeterSörös","domain_name":"uni-oldenburg","created_at":"2019-04-20T13:40:00.221-07:00","display_name":"Peter Sörös","url":"https://uni-oldenburg.academia.edu/PeterS%C3%B6r%C3%B6s"},"attachments":[{"id":93045032,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93045032/thumbnails/1.jpg","file_name":"EAR479554.pdf","download_url":"https://www.academia.edu/attachments/93045032/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Synthetic_Cannabinoid_Use_in_a_Psychiatr.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93045032/EAR479554-libre.pdf?1666723070=\u0026response-content-disposition=attachment%3B+filename%3DSynthetic_Cannabinoid_Use_in_a_Psychiatr.pdf\u0026Expires=1732413355\u0026Signature=UyKlgfKOXtjFxydxRha9vKsEKfCx-Gm-b~~XqrTvdmiOH7xoliro~DDvuXERq~QziX5r9ykft5EdkViwWa4NqzChMqt6-AUXxwxMyw2AtBeJ26j9hRuuW2TOz0Zz79uaay2HykKYB6LZuMWWfj23Nbf5VxSYigSPxKqgWx9ybhp-yN1Z641jzvtNDbCGH-q9zBICQSJ2fcPBeiSMsfV7zlur8PuXDZ3nCN2ctHuumoo-NJZNpv8g~jBKWb6QULzO~ghTuNxKgt9EFAulNokSN0DOAnPEnE1XoqdcDnh62jTzyA4GuXf3BwMLBe98zimLJ11qcW69-Zv1JhTaU63m2A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology"},{"id":635,"name":"Psychiatry","url":"https://www.academia.edu/Documents/in/Psychiatry"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":41788,"name":"Cannabinoids","url":"https://www.academia.edu/Documents/in/Cannabinoids"},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male"},{"id":238724,"name":"Cannabis","url":"https://www.academia.edu/Documents/in/Cannabis"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1"},{"id":562842,"name":"Psychiatric Hospitals","url":"https://www.academia.edu/Documents/in/Psychiatric_Hospitals"},{"id":612870,"name":"Psychotic Disorders","url":"https://www.academia.edu/Documents/in/Psychotic_Disorders"},{"id":945595,"name":"Pilot Projects","url":"https://www.academia.edu/Documents/in/Pilot_Projects"},{"id":1423077,"name":"Substance-Related Disorders","url":"https://www.academia.edu/Documents/in/Substance-Related_Disorders"},{"id":1907321,"name":"Marijuana abuse","url":"https://www.academia.edu/Documents/in/Marijuana_abuse"},{"id":2922956,"name":"Psychology and Cognitive Sciences","url":"https://www.academia.edu/Documents/in/Psychology_and_Cognitive_Sciences"},{"id":3763225,"name":"Medical and Health Sciences","url":"https://www.academia.edu/Documents/in/Medical_and_Health_Sciences"}],"urls":[{"id":25141408,"url":"https://www.karger.com/Article/Pdf/479554"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="89204519"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/89204519/Inattention_Predicts_Increased_Thickness_of_Left_Occipital_Cortex_in_Men_with_Attention_Deficit_Hyperactivity_Disorder"><img alt="Research paper thumbnail of Inattention Predicts Increased Thickness of Left Occipital Cortex in Men with Attention-Deficit/Hyperactivity Disorder" class="work-thumbnail" src="https://attachments.academia-assets.com/93045022/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89204519/Inattention_Predicts_Increased_Thickness_of_Left_Occipital_Cortex_in_Men_with_Attention_Deficit_Hyperactivity_Disorder">Inattention Predicts Increased Thickness of Left Occipital Cortex in Men with Attention-Deficit/Hyperactivity Disorder</a></div><div class="wp-workCard_item"><span>Frontiers in Psychiatry</span><span>, 2017</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="36ce105d275db48f5200483d5bb606de" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:93045022,&quot;asset_id&quot;:89204519,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/93045022/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="89204519"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="89204519"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 89204519; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=89204519]").text(description); $(".js-view-count[data-work-id=89204519]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 89204519; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='89204519']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 89204519, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "36ce105d275db48f5200483d5bb606de" } } $('.js-work-strip[data-work-id=89204519]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":89204519,"title":"Inattention Predicts Increased Thickness of Left Occipital Cortex in Men with Attention-Deficit/Hyperactivity Disorder","translated_title":"","metadata":{"publisher":"Frontiers Media SA","grobid_abstract":"Background: Attention-deficit/hyperactivity disorder (ADHD) in adulthood is a serious and frequent psychiatric disorder with the core symptoms inattention, impulsivity, and hyperactivity. The principal aim of this study was to investigate associations between brain morphology, i.e., cortical thickness and volumes of subcortical gray matter, and individual symptom severity in adult ADHD. Methods: Surface-based brain morphometry was performed in 35 women and 29 men with ADHD using FreeSurfer. Linear regressions were calculated between cortical thickness and the volumes of subcortical gray matter and the inattention, hyperactivity, and impulsivity subscales of the Conners Adult ADHD Rating Scales (CAARS). Two separate analyses were performed. For the first analysis, age was included as additional regressor. For the second analysis, both age and severity of depression were included as additional regressors. Study participants were recruited between June 2012 and January 2014. results: Linear regression identified an area in the left occipital cortex of men, covering parts of the middle occipital sulcus and gyrus, in which the score on the CAARS inattention subscale predicted increased mean cortical thickness [F(1,27) = 26.27, p \u003c 0.001, adjusted R 2 = 0.4744]. No significant associations were found between cortical thickness and the scores on CAARS subscales in women. No significant associations were found between the volumes of subcortical gray matter and the scores on CAARS subscales, neither in men nor in women. These results remained stable when severity of depression was included as additional regressor, together with age. conclusion: Increased cortical thickness in the left occipital cortex may represent a mechanism to compensate for dysfunctional attentional networks in male adult ADHD patients.","publication_date":{"day":null,"month":null,"year":2017,"errors":{}},"publication_name":"Frontiers in Psychiatry","grobid_abstract_attachment_id":93045022},"translated_abstract":null,"internal_url":"https://www.academia.edu/89204519/Inattention_Predicts_Increased_Thickness_of_Left_Occipital_Cortex_in_Men_with_Attention_Deficit_Hyperactivity_Disorder","translated_internal_url":"","created_at":"2022-10-25T10:40:29.213-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":109814020,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":93045022,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93045022/thumbnails/1.jpg","file_name":"85ebc0bace6123dcae8dac1ab6636acb788b.pdf","download_url":"https://www.academia.edu/attachments/93045022/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Inattention_Predicts_Increased_Thickness.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93045022/85ebc0bace6123dcae8dac1ab6636acb788b-libre.pdf?1666723075=\u0026response-content-disposition=attachment%3B+filename%3DInattention_Predicts_Increased_Thickness.pdf\u0026Expires=1732413355\u0026Signature=T7YOLT2Qto4MWOLoYFSgdDRWkSjgD6q1uOb22iPrhJcdfuxqpVl6V2HyxnPKTMg00GU8m-egd0jnK46i5wXYteiBh8OdyCLaBs6HaBSOJ6Yn21OpVQ~zEcA92M56PTmleb2oD-FT65ybnPhC5cIJH21ozx1ZfHWRSiEwWKvDKmCd3p7ruHbxfbog8nPHL2bpHCaygfHzGf6WTuo-91re9MF0Wn9hIY3bSfSsWdp7nCAByDNRJlcgcjZLqnPM8HhkYDhj2BZsCNm3oKXfD482LZpjTqtt~D8NmdXOEHccY84qTyjeiFdwHLmXqP38PVITWkcLZRtmOYDyy9dBf9w1aw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Inattention_Predicts_Increased_Thickness_of_Left_Occipital_Cortex_in_Men_with_Attention_Deficit_Hyperactivity_Disorder","translated_slug":"","page_count":11,"language":"en","content_type":"Work","owner":{"id":109814020,"first_name":"Peter","middle_initials":null,"last_name":"Sörös","page_name":"PeterSörös","domain_name":"uni-oldenburg","created_at":"2019-04-20T13:40:00.221-07:00","display_name":"Peter Sörös","url":"https://uni-oldenburg.academia.edu/PeterS%C3%B6r%C3%B6s"},"attachments":[{"id":93045022,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93045022/thumbnails/1.jpg","file_name":"85ebc0bace6123dcae8dac1ab6636acb788b.pdf","download_url":"https://www.academia.edu/attachments/93045022/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Inattention_Predicts_Increased_Thickness.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93045022/85ebc0bace6123dcae8dac1ab6636acb788b-libre.pdf?1666723075=\u0026response-content-disposition=attachment%3B+filename%3DInattention_Predicts_Increased_Thickness.pdf\u0026Expires=1732413355\u0026Signature=T7YOLT2Qto4MWOLoYFSgdDRWkSjgD6q1uOb22iPrhJcdfuxqpVl6V2HyxnPKTMg00GU8m-egd0jnK46i5wXYteiBh8OdyCLaBs6HaBSOJ6Yn21OpVQ~zEcA92M56PTmleb2oD-FT65ybnPhC5cIJH21ozx1ZfHWRSiEwWKvDKmCd3p7ruHbxfbog8nPHL2bpHCaygfHzGf6WTuo-91re9MF0Wn9hIY3bSfSsWdp7nCAByDNRJlcgcjZLqnPM8HhkYDhj2BZsCNm3oKXfD482LZpjTqtt~D8NmdXOEHccY84qTyjeiFdwHLmXqP38PVITWkcLZRtmOYDyy9dBf9w1aw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology"},{"id":8928,"name":"MRI","url":"https://www.academia.edu/Documents/in/MRI"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":2754641,"name":"Attention deficit hyperactivity disorder","url":"https://www.academia.edu/Documents/in/Attention_deficit_hyperactivity_disorder-1"}],"urls":[{"id":25141407,"url":"http://journal.frontiersin.org/article/10.3389/fpsyt.2017.00170/full"}]}, dispatcherData: dispatcherData }); 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Slow (2-6Hz) and beta (14-3OHz) activity were monitored up to 10 weeks. Results were compared with normative data, and changes over time were statistically analyzed. MEG detected pathological activity that persisted clinical symptoms. Focal slow activity originating from sensorimotor (TIA) and mesiotemporal (TGA) cortices exceeded normal values up to 14 times during the first hours after the attack and recovered to normal within 11 days. Focal beta activity was not useful to monitor the tinne course of TIA or 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$a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="89204516"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/89204516/The_neurochemical_basis_of_human_cortical_auditory_processing_combining_proton_magnetic_resonance_spectroscopy_and_magnetoencephalography"><img alt="Research paper thumbnail of The neurochemical basis of human cortical auditory processing: combining proton magnetic resonance spectroscopy and magnetoencephalography" class="work-thumbnail" src="https://attachments.academia-assets.com/93045061/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89204516/The_neurochemical_basis_of_human_cortical_auditory_processing_combining_proton_magnetic_resonance_spectroscopy_and_magnetoencephalography">The neurochemical basis of human cortical auditory processing: combining proton magnetic resonance spectroscopy and magnetoencephalography</a></div><div class="wp-workCard_item"><span>Bmc Biology</span><span>, 2006</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="f1373a5b7d992f249c720b4256382ca4" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:93045061,&quot;asset_id&quot;:89204516,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/93045061/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa 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})(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "f1373a5b7d992f249c720b4256382ca4" } } $('.js-work-strip[data-work-id=89204516]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":89204516,"title":"The neurochemical basis of human cortical auditory processing: combining proton magnetic resonance spectroscopy and magnetoencephalography","translated_title":"","metadata":{"grobid_abstract":"Background: A combination of magnetoencephalography and proton magnetic resonance spectroscopy was used to correlate the electrophysiology of rapid auditory processing and the neurochemistry of the auditory cortex in 15 healthy adults. To assess rapid auditory processing in the left auditory cortex, the amplitude and decrement of the N1m peak, the major component of the late auditory evoked response, were measured during rapidly successive presentation of acoustic stimuli. We tested the hypothesis that: (i) the amplitude of the N1m response and (ii) its decrement during rapid stimulation are associated with the cortical neurochemistry as determined by proton magnetic resonance spectroscopy. Results: Our results demonstrated a significant association between the concentrations of Nacetylaspartate, a marker of neuronal integrity, and the amplitudes of individual N1m responses. In addition, the concentrations of choline-containing compounds, representing the functional integrity of membranes, were significantly associated with N1m amplitudes. No significant association was found between the concentrations of the glutamate/glutamine pool and the amplitudes of the first N1m. No significant associations were seen between the decrement of the N1m (the relative amplitude of the second N1m peak) and the concentrations of N-acetylaspartate, cholinecontaining compounds, or the glutamate/glutamine pool. However, there was a trend for higher glutamate/glutamine concentrations in individuals with higher relative N1m amplitude. Conclusion: These results suggest that neuronal and membrane functions are important for rapid auditory processing. This investigation provides a first link between the electrophysiology, as recorded by magnetoencephalography, and the neurochemistry, as assessed by proton magnetic resonance spectroscopy, of the auditory cortex. Background Hearing is one of the fundamental and most important abilities of the vertebrate nervous system. The neurophysiology of the auditory system is increasingly well under","publication_date":{"day":null,"month":null,"year":2006,"errors":{}},"publication_name":"Bmc 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processing","url":"https://www.academia.edu/Documents/in/Auditory_temporal_processing"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":382341,"name":"Glutamine","url":"https://www.academia.edu/Documents/in/Glutamine"},{"id":546419,"name":"Age Factors","url":"https://www.academia.edu/Documents/in/Age_Factors"},{"id":723371,"name":"Auditory Cortex","url":"https://www.academia.edu/Documents/in/Auditory_Cortex"},{"id":990296,"name":"Choline","url":"https://www.academia.edu/Documents/in/Choline"},{"id":1292998,"name":"Glutamic Acid","url":"https://www.academia.edu/Documents/in/Glutamic_Acid"},{"id":2012816,"name":"Glutamate 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wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89204515/fMRI_compatible_registration_of_jaw_movements_using_a_fiber_optic_bend_sensor">fMRI-compatible registration of jaw movements using a fiber-optic bend sensor</a></div><div class="wp-workCard_item"><span>Frontiers in Human Neuroscience</span><span>, 2010</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="e254798058100ca71b11276afdd55a00" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:93045007,&quot;asset_id&quot;:89204515,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/93045007/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa 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})(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "e254798058100ca71b11276afdd55a00" } } $('.js-work-strip[data-work-id=89204515]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":89204515,"title":"fMRI-compatible registration of jaw movements using a fiber-optic bend sensor","translated_title":"","metadata":{"grobid_abstract":"To study speech-related movements outside MRI systems, surface electromyography (EMG) is widely used (Smith, 1992). In positron emission tomography (Murphy et al., 1997) and magnetoencephalography (Sörös et al., 2003), EMG has also been used frequently and successfully to monitor muscle function associated with overt speech production. The use of EMG in fMRI studies, however, is challenging (for a recent review on the recording of electrophysiological data during fMRI, see Laufs et al., 2008). Time-varying radiofrequency pulses and magnetic fi eld gradients may induce artifacts in EMG recordings and, conversely, movements of EMG electrodes and leads inside the magnetic fi eld may cause artifacts in fMRI data (Ganesh et al., 2007; MacIntosh et al., 2007). In addition, the use of EMG in an fMRI study is limited by the need of an fMRI-compatible EMG system (e.g., BrainAmp, Brain Products, Gilching, Germany 1), specialized EMG data postprocessing (van Duinen et al., 2005; MacIntosh et al., 2007), and by time constraints. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="89204513"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/89204513/Phantom_sensations_following_acute_pain"><img alt="Research paper thumbnail of Phantom sensations following acute pain" class="work-thumbnail" src="https://attachments.academia-assets.com/93045023/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89204513/Phantom_sensations_following_acute_pain">Phantom sensations following acute pain</a></div><div class="wp-workCard_item"><span>Pain</span><span>, 1998</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="2ea14000e206b08d3547f613ca0fcb0b" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:93045023,&quot;asset_id&quot;:89204513,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/93045023/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="89204513"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="89204513"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 89204513; 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A similar phenomenon was incidentally encountered in healthy subjects. For reasons unrelated to the question of mislocalization, we performed a study involving the application of experimental acute pain to the hand followed by non-noxious tactile stimulation of the ipsilateral lip. During lip stimulation, two out of six subjects spontaneously reported perceiving an additional phantom-like sensation in the hand synchronously to the non-noxious lip stimulation. Similar, although more diffuse, phantom sensations were observed in two out of seven additional subjects who were then tested specifically for this effect. The observation is compatible with a pain-induced hyperresponsiveness of the cortical hand area to somatotopically adjacent inputs from the lip. This suggests that, even in the absence of deafferentation, pain can lead to a representational reorganization.","publication_date":{"day":null,"month":null,"year":1998,"errors":{}},"publication_name":"Pain","grobid_abstract_attachment_id":93045023},"translated_abstract":null,"internal_url":"https://www.academia.edu/89204513/Phantom_sensations_following_acute_pain","translated_internal_url":"","created_at":"2022-10-25T10:40:27.807-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":109814020,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":93045023,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93045023/thumbnails/1.jpg","file_name":"s0304-3959_2898_2900102-x20221025-1-11q34lf.pdf","download_url":"https://www.academia.edu/attachments/93045023/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Phantom_sensations_following_acute_pain.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93045023/s0304-3959_2898_2900102-x20221025-1-11q34lf-libre.pdf?1666723069=\u0026response-content-disposition=attachment%3B+filename%3DPhantom_sensations_following_acute_pain.pdf\u0026Expires=1732413355\u0026Signature=Uvt8tyduBxtb-HQZ3KlZ6gQE0ZTYeYA1AbUpfAAYLxtywObSJmpemwEyblnGbTfmhe0-N14EsqXHizFaLGeFoNXMHs2m1jq6kMcGj4tZkj0LbKm1PYItJ0szz1dJ9JEMfc4L1YHVtvFtNk9e8oShxirXFKQCwb2QKfeDKzlyHP1WXVUbg8BFIrP6P2p1IbUhcq6vPikA8r08HqsGfjdtRCDQQCE5kRszdbKnDBwa-OAOFoKYxr1Qm3s3eQgBLm0rLuAQYEvE1v-VFwPEQ~aWihOVU1eAit8UQnsoo0ggOII9SroebhHuM-XHOKmGYUWxt6chSpnGxAp0940AFxJALA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Phantom_sensations_following_acute_pain","translated_slug":"","page_count":5,"language":"en","content_type":"Work","owner":{"id":109814020,"first_name":"Peter","middle_initials":null,"last_name":"Sörös","page_name":"PeterSörös","domain_name":"uni-oldenburg","created_at":"2019-04-20T13:40:00.221-07:00","display_name":"Peter Sörös","url":"https://uni-oldenburg.academia.edu/PeterS%C3%B6r%C3%B6s"},"attachments":[{"id":93045023,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93045023/thumbnails/1.jpg","file_name":"s0304-3959_2898_2900102-x20221025-1-11q34lf.pdf","download_url":"https://www.academia.edu/attachments/93045023/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Phantom_sensations_following_acute_pain.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93045023/s0304-3959_2898_2900102-x20221025-1-11q34lf-libre.pdf?1666723069=\u0026response-content-disposition=attachment%3B+filename%3DPhantom_sensations_following_acute_pain.pdf\u0026Expires=1732413355\u0026Signature=Uvt8tyduBxtb-HQZ3KlZ6gQE0ZTYeYA1AbUpfAAYLxtywObSJmpemwEyblnGbTfmhe0-N14EsqXHizFaLGeFoNXMHs2m1jq6kMcGj4tZkj0LbKm1PYItJ0szz1dJ9JEMfc4L1YHVtvFtNk9e8oShxirXFKQCwb2QKfeDKzlyHP1WXVUbg8BFIrP6P2p1IbUhcq6vPikA8r08HqsGfjdtRCDQQCE5kRszdbKnDBwa-OAOFoKYxr1Qm3s3eQgBLm0rLuAQYEvE1v-VFwPEQ~aWihOVU1eAit8UQnsoo0ggOII9SroebhHuM-XHOKmGYUWxt6chSpnGxAp0940AFxJALA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":2380,"name":"Plasticity","url":"https://www.academia.edu/Documents/in/Plasticity"},{"id":2898,"name":"Pain","url":"https://www.academia.edu/Documents/in/Pain"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":75075,"name":"Phantom limb","url":"https://www.academia.edu/Documents/in/Phantom_limb"},{"id":82660,"name":"Sensation","url":"https://www.academia.edu/Documents/in/Sensation"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male"},{"id":132020,"name":"Neuronal Plasticity","url":"https://www.academia.edu/Documents/in/Neuronal_Plasticity"},{"id":138306,"name":"Phantom Pain","url":"https://www.academia.edu/Documents/in/Phantom_Pain"},{"id":277717,"name":"Somatosensory Cortex","url":"https://www.academia.edu/Documents/in/Somatosensory_Cortex"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":541937,"name":"Stimulation","url":"https://www.academia.edu/Documents/in/Stimulation"},{"id":1142759,"name":"Healthy Subjects","url":"https://www.academia.edu/Documents/in/Healthy_Subjects"},{"id":2471455,"name":"Acute Disease","url":"https://www.academia.edu/Documents/in/Acute_Disease"},{"id":2922956,"name":"Psychology and Cognitive Sciences","url":"https://www.academia.edu/Documents/in/Psychology_and_Cognitive_Sciences"},{"id":3763225,"name":"Medical and Health Sciences","url":"https://www.academia.edu/Documents/in/Medical_and_Health_Sciences"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="89204512"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/89204512/A_Study_of_Brain_Networks_Associated_with_Swallowing_Using_Graph_Theoretical_Approaches"><img alt="Research paper thumbnail of A Study of Brain Networks Associated with Swallowing Using Graph-Theoretical Approaches" class="work-thumbnail" src="https://attachments.academia-assets.com/93045001/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89204512/A_Study_of_Brain_Networks_Associated_with_Swallowing_Using_Graph_Theoretical_Approaches">A Study of Brain Networks Associated with Swallowing Using Graph-Theoretical Approaches</a></div><div class="wp-workCard_item"><span>PLoS ONE</span><span>, 2013</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="cea575a6408b0df66dd2930260d045d3" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:93045001,&quot;asset_id&quot;:89204512,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/93045001/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="89204512"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="89204512"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 89204512; 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Understanding these complex interactions is of great interest from both a scientific and a clinical perspective. In this study, functional magnetic resonance imaging (fMRI) was utilized to study brain functional networks during voluntary saliva swallowing in twenty-two adult healthy subjects (all females, 23:1+1:52 years of age). To construct these functional connections, we computed mean partial correlation matrices over ninety brain regions for each participant. Two regions were determined to be functionally connected if their correlation was above a certain threshold. These correlation matrices were then analyzed using graphtheoretical approaches. In particular, we considered several network measures for the whole brain and for swallowingrelated brain regions. The results have shown that significant pairwise functional connections were, mostly, either local and intra-hemispheric or symmetrically inter-hemispheric. Furthermore, we showed that all human brain functional network, although varying in some degree, had typical small-world properties as compared to regular networks and random networks. These properties allow information transfer within the network at a relatively high efficiency. Swallowing-related brain regions also had higher values for some of the network measures in comparison to when these measures were calculated for the whole brain. The current results warrant further investigation of graph-theoretical approaches as a potential tool for understanding the neural basis of dysphagia.","publication_date":{"day":null,"month":null,"year":2013,"errors":{}},"publication_name":"PLoS ONE","grobid_abstract_attachment_id":93045001},"translated_abstract":null,"internal_url":"https://www.academia.edu/89204512/A_Study_of_Brain_Networks_Associated_with_Swallowing_Using_Graph_Theoretical_Approaches","translated_internal_url":"","created_at":"2022-10-25T10:40:27.317-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":109814020,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":93045001,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93045001/thumbnails/1.jpg","file_name":"5a812d80bec3f11e0fcb5528de0140941e11.pdf","download_url":"https://www.academia.edu/attachments/93045001/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"A_Study_of_Brain_Networks_Associated_wit.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93045001/5a812d80bec3f11e0fcb5528de0140941e11-libre.pdf?1666723075=\u0026response-content-disposition=attachment%3B+filename%3DA_Study_of_Brain_Networks_Associated_wit.pdf\u0026Expires=1732413355\u0026Signature=RsNmvI2g55LrQroQhbqNjCey4cUsTonbEuJJ07MhTqYgNi5PLD4JuulbXY4HQuCyq5-VuefYPeM9JM9LrNyPoUR35FOSc8RZJQY3VArfbKbujJ0wKTNnGga5c7RUiIwuTZKVs8Mey6gcLnvjVUv1hIFmMpfY7oX7MZsNF~0CbSTe~Lg6SueDg6Ixxo2jPDsaDPzGWEMTyHj5TCgd3YFP01PpahJ~IK4YC~b6axiYyqhBN4XC6DRCDVeZCl81nc~97s-KV7QyCTAFMS1Bh-fEfLxr7zrxru0HzAXYOxXNdUaWc3bBFffOZXcGid9ol9f4WjwfxGGImdWpySLT1A7nMg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"A_Study_of_Brain_Networks_Associated_with_Swallowing_Using_Graph_Theoretical_Approaches","translated_slug":"","page_count":11,"language":"en","content_type":"Work","owner":{"id":109814020,"first_name":"Peter","middle_initials":null,"last_name":"Sörös","page_name":"PeterSörös","domain_name":"uni-oldenburg","created_at":"2019-04-20T13:40:00.221-07:00","display_name":"Peter Sörös","url":"https://uni-oldenburg.academia.edu/PeterS%C3%B6r%C3%B6s"},"attachments":[{"id":93045001,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93045001/thumbnails/1.jpg","file_name":"5a812d80bec3f11e0fcb5528de0140941e11.pdf","download_url":"https://www.academia.edu/attachments/93045001/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"A_Study_of_Brain_Networks_Associated_wit.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93045001/5a812d80bec3f11e0fcb5528de0140941e11-libre.pdf?1666723075=\u0026response-content-disposition=attachment%3B+filename%3DA_Study_of_Brain_Networks_Associated_wit.pdf\u0026Expires=1732413355\u0026Signature=RsNmvI2g55LrQroQhbqNjCey4cUsTonbEuJJ07MhTqYgNi5PLD4JuulbXY4HQuCyq5-VuefYPeM9JM9LrNyPoUR35FOSc8RZJQY3VArfbKbujJ0wKTNnGga5c7RUiIwuTZKVs8Mey6gcLnvjVUv1hIFmMpfY7oX7MZsNF~0CbSTe~Lg6SueDg6Ixxo2jPDsaDPzGWEMTyHj5TCgd3YFP01PpahJ~IK4YC~b6axiYyqhBN4XC6DRCDVeZCl81nc~97s-KV7QyCTAFMS1Bh-fEfLxr7zrxru0HzAXYOxXNdUaWc3bBFffOZXcGid9ol9f4WjwfxGGImdWpySLT1A7nMg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":422,"name":"Computer Science","url":"https://www.academia.edu/Documents/in/Computer_Science"},{"id":428,"name":"Algorithms","url":"https://www.academia.edu/Documents/in/Algorithms"},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging"},{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":28235,"name":"Multidisciplinary","url":"https://www.academia.edu/Documents/in/Multidisciplinary"},{"id":52176,"name":"Brain Mapping","url":"https://www.academia.edu/Documents/in/Brain_Mapping"},{"id":61474,"name":"Brain","url":"https://www.academia.edu/Documents/in/Brain"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":82955,"name":"Swallowing","url":"https://www.academia.edu/Documents/in/Swallowing"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult"},{"id":220780,"name":"PLoS one","url":"https://www.academia.edu/Documents/in/PLoS_one"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":2444775,"name":"Psychomotor Performance","url":"https://www.academia.edu/Documents/in/Psychomotor_Performance"},{"id":3275398,"name":"Deglutition","url":"https://www.academia.edu/Documents/in/Deglutition"}],"urls":[{"id":25141406,"url":"http://dx.plos.org/10.1371/journal.pone.0073577"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="89204510"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/89204510/Current_source_density_distribution_of_sleep_spindles_in_humans_as_found_by_synthetic_aperture_magnetometry"><img alt="Research paper thumbnail of Current source density distribution of sleep spindles in humans as found by synthetic aperture magnetometry" class="work-thumbnail" src="https://attachments.academia-assets.com/93045015/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89204510/Current_source_density_distribution_of_sleep_spindles_in_humans_as_found_by_synthetic_aperture_magnetometry">Current source density distribution of sleep spindles in humans as found by synthetic aperture magnetometry</a></div><div class="wp-workCard_item"><span>Neuroscience Letters</span><span>, 2003</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="3a7df9152c69f4cec43924d22ad16244" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:93045015,&quot;asset_id&quot;:89204510,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/93045015/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="89204510"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="89204510"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 89204510; 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dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "3a7df9152c69f4cec43924d22ad16244" } } $('.js-work-strip[data-work-id=89204510]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":89204510,"title":"Current source density distribution of sleep spindles in humans as found by synthetic aperture magnetometry","translated_title":"","metadata":{"publisher":"Elsevier BV","grobid_abstract":"Previous magnetoencephalography (MEG) studies of sleep spindles have identified a complex and widespread distribution in parietal and frontal cortices by fitting a dipolar model to the data. In this study, we used a whole-head 151-channel MEG system with simultaneous electroencephalography (EEG) recording in eight normal subjects. All subjects fell asleep during stage 2 and 3; EEG spindles have been observed in all cases. The current source density distribution of sleep spindles in the 10-15 Hz frequency band was localized by means of synthetic aperture magnetometry, and statistically tested using a permutation analysis. Source locations of the sleep spindles were found primarily in the frontal cortex, including dorsolateral and medial prefrontal areas, as well as the parietal cortex, including the vicinity of the primary sensorimotor areas. These results suggest that sleep spindles are similar in frequency content and spatial location to mu rhythm, and that these two oscillatory activities might also have a common neural basis and physiological meaning.","publication_date":{"day":null,"month":null,"year":2003,"errors":{}},"publication_name":"Neuroscience 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href="https://www.academia.edu/89204505/Altered_Habituation_in_the_Auditory_Cortex_in_a_Subgroup_of_Depressed_Patients_by_Functional_Magnetic_Resonance_Imaging"><img alt="Research paper thumbnail of Altered Habituation in the Auditory Cortex in a Subgroup of Depressed Patients by Functional Magnetic Resonance Imaging" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89204505/Altered_Habituation_in_the_Auditory_Cortex_in_a_Subgroup_of_Depressed_Patients_by_Functional_Magnetic_Resonance_Imaging">Altered Habituation in the Auditory Cortex in a Subgroup of Depressed Patients by Functional Magnetic Resonance Imaging</a></div><div class="wp-workCard_item"><span>Neuropsychobiology</span><span>, 2004</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The aim of this study was to measure and quantify habituation effects to auditory stimulation wit...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The aim of this study was to measure and quantify habituation effects to auditory stimulation within the auditory cortex of 11 depressed patients with major depressive disorder compared to 11 healthy subjects. Habituation was visualized by functional magnetic resonance imaging (fMRI) employing a block design (repeated stimulation with sine tones). A subgroup of patients (n = 5) presented the following abnormal habituation fMRI pattern: significantly lower activation after the first stimulation block (p = 0.05), missing characteristic signal decay to repeated acoustic stimulation and a marked undershoot after each stimulation block. This abnormal pattern may indicate functional deficits in auditory processing occurring with depression, but our results need be confirmed in a larger, more homogeneous patient group. This paradigm may be a useful tool for assessing cortical dysfunction in mood disorders.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="89204505"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="89204505"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 89204505; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=89204505]").text(description); $(".js-view-count[data-work-id=89204505]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 89204505; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='89204505']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 89204505, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=89204505]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":89204505,"title":"Altered Habituation in the Auditory Cortex in a Subgroup of Depressed Patients by Functional Magnetic Resonance Imaging","translated_title":"","metadata":{"abstract":"The aim of this study was to measure and quantify habituation effects to auditory stimulation within the auditory cortex of 11 depressed patients with major depressive disorder compared to 11 healthy subjects. Habituation was visualized by functional magnetic resonance imaging (fMRI) employing a block design (repeated stimulation with sine tones). A subgroup of patients (n = 5) presented the following abnormal habituation fMRI pattern: significantly lower activation after the first stimulation block (p = 0.05), missing characteristic signal decay to repeated acoustic stimulation and a marked undershoot after each stimulation block. This abnormal pattern may indicate functional deficits in auditory processing occurring with depression, but our results need be confirmed in a larger, more homogeneous patient group. This paradigm may be a useful tool for assessing cortical dysfunction in mood disorders.","publisher":"S. Karger AG","publication_date":{"day":null,"month":null,"year":2004,"errors":{}},"publication_name":"Neuropsychobiology"},"translated_abstract":"The aim of this study was to measure and quantify habituation effects to auditory stimulation within the auditory cortex of 11 depressed patients with major depressive disorder compared to 11 healthy subjects. Habituation was visualized by functional magnetic resonance imaging (fMRI) employing a block design (repeated stimulation with sine tones). A subgroup of patients (n = 5) presented the following abnormal habituation fMRI pattern: significantly lower activation after the first stimulation block (p = 0.05), missing characteristic signal decay to repeated acoustic stimulation and a marked undershoot after each stimulation block. This abnormal pattern may indicate functional deficits in auditory processing occurring with depression, but our results need be confirmed in a larger, more homogeneous patient group. This paradigm may be a useful tool for assessing cortical dysfunction in mood disorders.","internal_url":"https://www.academia.edu/89204505/Altered_Habituation_in_the_Auditory_Cortex_in_a_Subgroup_of_Depressed_Patients_by_Functional_Magnetic_Resonance_Imaging","translated_internal_url":"","created_at":"2022-10-25T10:40:26.261-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":109814020,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Altered_Habituation_in_the_Auditory_Cortex_in_a_Subgroup_of_Depressed_Patients_by_Functional_Magnetic_Resonance_Imaging","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":109814020,"first_name":"Peter","middle_initials":null,"last_name":"Sörös","page_name":"PeterSörös","domain_name":"uni-oldenburg","created_at":"2019-04-20T13:40:00.221-07:00","display_name":"Peter Sörös","url":"https://uni-oldenburg.academia.edu/PeterS%C3%B6r%C3%B6s"},"attachments":[],"research_interests":[{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science"},{"id":3217,"name":"Depression","url":"https://www.academia.edu/Documents/in/Depression"},{"id":4139,"name":"Audiology","url":"https://www.academia.edu/Documents/in/Audiology"},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging"},{"id":52176,"name":"Brain Mapping","url":"https://www.academia.edu/Documents/in/Brain_Mapping"},{"id":58520,"name":"Habituation","url":"https://www.academia.edu/Documents/in/Habituation"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":84318,"name":"Auditory Processing","url":"https://www.academia.edu/Documents/in/Auditory_Processing"},{"id":97765,"name":"Functional Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Functional_Magnetic_Resonance_Imaging"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":100946,"name":"Functional Imaging","url":"https://www.academia.edu/Documents/in/Functional_Imaging"},{"id":157943,"name":"Depressive Disorder","url":"https://www.academia.edu/Documents/in/Depressive_Disorder"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":723371,"name":"Auditory Cortex","url":"https://www.academia.edu/Documents/in/Auditory_Cortex"},{"id":1142759,"name":"Healthy Subjects","url":"https://www.academia.edu/Documents/in/Healthy_Subjects"},{"id":1236957,"name":"Block Design","url":"https://www.academia.edu/Documents/in/Block_Design"},{"id":1355489,"name":"Affective Disorder","url":"https://www.academia.edu/Documents/in/Affective_Disorder"},{"id":1819399,"name":"Case Control Studies","url":"https://www.academia.edu/Documents/in/Case_Control_Studies"},{"id":2428413,"name":"Acoustic Stimulation","url":"https://www.academia.edu/Documents/in/Acoustic_Stimulation"}],"urls":[{"id":25141402,"url":"https://www.karger.com/Article/Pdf/75331"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="89204502"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/89204502/Naming_actions_and_objects_cortical_dynamics_in_healthy_adults_and_in_an_anomic_patient_with_a_dissociation_in_action_object_naming"><img alt="Research paper thumbnail of Naming actions and objects: cortical dynamics in healthy adults and in an anomic patient with a dissociation in action/object naming" class="work-thumbnail" src="https://attachments.academia-assets.com/93045059/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89204502/Naming_actions_and_objects_cortical_dynamics_in_healthy_adults_and_in_an_anomic_patient_with_a_dissociation_in_action_object_naming">Naming actions and objects: cortical dynamics in healthy adults and in an anomic patient with a dissociation in action/object naming</a></div><div class="wp-workCard_item"><span>NeuroImage</span><span>, 2003</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="86012d3fa6c51624a7c72cc9110f7c4f" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:93045059,&quot;asset_id&quot;:89204502,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/93045059/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="89204502"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="89204502"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 89204502; 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These reports have been taken as evidence for separate representations of nouns and verbs in the human brain. We used whole-head magnetoencephalography to record cortical dynamics of action and object naming in 10 healthy adults and in 1 anomic patient with superior naming of verbs compared with nouns due to a left posterior parietal lesion. A single set of 100 line drawings was used for both action and object naming. In normal subjects, the activation sequences in action and object naming were essentially identical, advancing from the occipital to posterior temporoparietal and further to the left frontal cortex, without consistent involvement of the classical left inferior frontal (Broca) and temporal (Wernicke) language areas. In the anomic patient, pronounced differences between action and object naming emerged in the left hemisphere. The activation sequence was disrupted at the level of the damaged parietal cortex and did not reach the left frontal cortex even in the relatively easier action naming. The more severely impaired object naming was associated with exceptionally strong and early activation of the left inferior frontal cortex (Broca) and subsequent pronounced activation of the left middle temporal cortex, silent in action naming. Verb and noun retrieval thus utilized a spatiotemporally similar neuronal network in healthy individuals. A clear dissociation in cortical correlates of verb and noun retrieval only became evident in our anomic patient, in whom damage to the language network has resulted in disproportionately worse performance in object than action naming.","publication_date":{"day":null,"month":null,"year":2003,"errors":{}},"publication_name":"NeuroImage","grobid_abstract_attachment_id":93045059},"translated_abstract":null,"internal_url":"https://www.academia.edu/89204502/Naming_actions_and_objects_cortical_dynamics_in_healthy_adults_and_in_an_anomic_patient_with_a_dissociation_in_action_object_naming","translated_internal_url":"","created_at":"2022-10-25T10:40:25.952-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":109814020,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":93045059,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93045059/thumbnails/1.jpg","file_name":"s1053-8119_2803_2900217-920221025-1-1bkcm7r.pdf","download_url":"https://www.academia.edu/attachments/93045059/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Naming_actions_and_objects_cortical_dyna.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93045059/s1053-8119_2803_2900217-920221025-1-1bkcm7r-libre.pdf?1666723068=\u0026response-content-disposition=attachment%3B+filename%3DNaming_actions_and_objects_cortical_dyna.pdf\u0026Expires=1732413355\u0026Signature=QY3EPphFnIUJ1VgCNimGSqfsjXUN6QiqPYjpen1E8TqjItzaFnslGE18rNbBoWhdDhTHQTuw9jIqQqEk3Mt-Kjt-Z4Y0nuAlUBNcykqqFjAWKTJT7EF3GpE-kihRyjdYylmvuVnluvEzf7Nl1oqR-8a~LyJlKlG-HTmNwleIcwNVppNuMKrW0qfa4xWBEr3b44MnJNXEubPYecQ3axEz40fAxArtuRnNMbd9rX-6kav16~rlOFV7ne1xl7q3ESCD0VMqQqRxDh5z~lhDU6VklR22N3FWUj3TNSHsbz~tRuGrTtVvaB3Gv4S3TlMrS28eL5NZ2fcVUhDYz01276sMYA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Naming_actions_and_objects_cortical_dynamics_in_healthy_adults_and_in_an_anomic_patient_with_a_dissociation_in_action_object_naming","translated_slug":"","page_count":15,"language":"en","content_type":"Work","owner":{"id":109814020,"first_name":"Peter","middle_initials":null,"last_name":"Sörös","page_name":"PeterSörös","domain_name":"uni-oldenburg","created_at":"2019-04-20T13:40:00.221-07:00","display_name":"Peter 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src="https://attachments.academia-assets.com/93044998/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89204500/Time_course_of_focal_pathological_activity_in_TIA_and_TGA_investigated_by_magnetoencephalography">Time course of focal pathological activity in TIA and TGA investigated by magnetoencephalography</a></div><div class="wp-workCard_item"><span>NeuroImage</span><span>, 2000</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="f5fa857c1e31938e774ff78a46e76f1c" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" 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neuroanatomy of overt speech production" class="work-thumbnail" src="https://attachments.academia-assets.com/93045086/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89204498/Age_related_changes_in_the_functional_neuroanatomy_of_overt_speech_production">Age-related changes in the functional neuroanatomy of overt speech production</a></div><div class="wp-workCard_item"><span>Neurobiology of Aging</span><span>, 2011</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="d00b021543e8155192047132482cf8a5" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" 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healthy aging, resulting in behavioral deficits and changes in brain activity, have been described for cognitive, motor, and sensory functions. To investigate age-related changes in the neural circuitry underlying overt non-lexical speech production, functional MRI was performed in 14 healthy younger (21-32 years) and 14 healthy older individuals (62-84 years). The experimental task involved the acoustically cued overt production of the vowel /a/ and the polysyllabic utterance /pataka/. In younger and older individuals, overt speech production was associated with the activation of a widespread articulo-phonological network, including the primary motor cortex, the supplementary motor area, the cingulate motor areas, and the posterior superior temporal cortex, similar in the /a/ and /pataka/ condition. An analysis of variance with the factors age and condition revealed a significant main effect of age. Irrespective of the experimental condition, significantly greater activation was found in the bilateral posterior superior temporal cortex, the posterior temporal plane, and the transverse temporal gyri in younger compared to older individuals. Significantly greater activation was found in the bilateral middle temporal gyri, medial frontal gyri, middle frontal gyri, and inferior frontal gyri in older vs. younger individuals. The analysis of variance did not reveal a significant main effect of condition and no significant interaction of age and condition. These results suggest a complex reorganization of neural networks dedicated to the production of speech during healthy aging.","publication_date":{"day":null,"month":null,"year":2011,"errors":{}},"publication_name":"Neurobiology of Aging","grobid_abstract_attachment_id":93045086},"translated_abstract":null,"internal_url":"https://www.academia.edu/89204498/Age_related_changes_in_the_functional_neuroanatomy_of_overt_speech_production","translated_internal_url":"","created_at":"2022-10-25T10:40:25.210-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":109814020,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":93045086,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93045086/thumbnails/1.jpg","file_name":"sorosnba2009.pdf","download_url":"https://www.academia.edu/attachments/93045086/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Age_related_changes_in_the_functional_ne.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93045086/sorosnba2009-libre.pdf?1666723063=\u0026response-content-disposition=attachment%3B+filename%3DAge_related_changes_in_the_functional_ne.pdf\u0026Expires=1732413355\u0026Signature=XMJGkb78d-oQlmHJNTe4AsGzsDT7Vk3RANnCanqIDfnhB~XX7h5qoeRxJpJ6n3C-JQVW31dx8qFUmdXSdOQovw92o4gEmI1taj31KsVtxZmIW7eQO8DNN3FgV82fEieyZB7OgFKoxdx9S246Nmv7HY~NQzrRSFaT1ka5vc2x2LsHs~zgk5ly2Rjogn5~iXI6fi8dWyqbSIqUHAPMciaZAMP-u399RBN8pvjy2EGDXsK2la0Fl5mcIrkVLfTiwUSC-vukhH54K-OwBhdR1bMQHGQJTdyUCSjcMUIDqOgawAQVP48WoJh61g-GThDgGE51RloMqy7HCZe~4dgrzREz0g__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Age_related_changes_in_the_functional_neuroanatomy_of_overt_speech_production","translated_slug":"","page_count":9,"language":"en","content_type":"Work","owner":{"id":109814020,"first_name":"Peter","middle_initials":null,"last_name":"Sörös","page_name":"PeterSörös","domain_name":"uni-oldenburg","created_at":"2019-04-20T13:40:00.221-07:00","display_name":"Peter Sörös","url":"https://uni-oldenburg.academia.edu/PeterS%C3%B6r%C3%B6s"},"attachments":[{"id":93045086,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93045086/thumbnails/1.jpg","file_name":"sorosnba2009.pdf","download_url":"https://www.academia.edu/attachments/93045086/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Age_related_changes_in_the_functional_ne.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93045086/sorosnba2009-libre.pdf?1666723063=\u0026response-content-disposition=attachment%3B+filename%3DAge_related_changes_in_the_functional_ne.pdf\u0026Expires=1732413355\u0026Signature=XMJGkb78d-oQlmHJNTe4AsGzsDT7Vk3RANnCanqIDfnhB~XX7h5qoeRxJpJ6n3C-JQVW31dx8qFUmdXSdOQovw92o4gEmI1taj31KsVtxZmIW7eQO8DNN3FgV82fEieyZB7OgFKoxdx9S246Nmv7HY~NQzrRSFaT1ka5vc2x2LsHs~zgk5ly2Rjogn5~iXI6fi8dWyqbSIqUHAPMciaZAMP-u399RBN8pvjy2EGDXsK2la0Fl5mcIrkVLfTiwUSC-vukhH54K-OwBhdR1bMQHGQJTdyUCSjcMUIDqOgawAQVP48WoJh61g-GThDgGE51RloMqy7HCZe~4dgrzREz0g__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":4139,"name":"Audiology","url":"https://www.academia.edu/Documents/in/Audiology"},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging"},{"id":6791,"name":"Aging","url":"https://www.academia.edu/Documents/in/Aging"},{"id":9224,"name":"Functional MRI","url":"https://www.academia.edu/Documents/in/Functional_MRI"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":29917,"name":"FMRI","url":"https://www.academia.edu/Documents/in/FMRI"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":78467,"name":"Cerebral Cortex","url":"https://www.academia.edu/Documents/in/Cerebral_Cortex"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":295155,"name":"Middle Aged","url":"https://www.academia.edu/Documents/in/Middle_Aged"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":413194,"name":"Analysis of Variance","url":"https://www.academia.edu/Documents/in/Analysis_of_Variance"}],"urls":[{"id":25141398,"url":"https://api.elsevier.com/content/article/PII:S0197458009002942?httpAccept=text/xml"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> </div><div class="profile--tab_content_container js-tab-pane tab-pane" data-section-id="9100329" id="papers"><div class="js-work-strip profile--work_container" data-work-id="104382968"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/104382968/Diffusion_tensor_imaging_of_white_matter_microstructure_in_chronic_pain_a_tract_based_spatial_statistics_study_and_a_systematic_review"><img alt="Research paper thumbnail of Diffusion tensor imaging of white matter microstructure in chronic pain: a tract-based spatial statistics study and a systematic review" class="work-thumbnail" src="https://attachments.academia-assets.com/104128402/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/104382968/Diffusion_tensor_imaging_of_white_matter_microstructure_in_chronic_pain_a_tract_based_spatial_statistics_study_and_a_systematic_review">Diffusion tensor imaging of white matter microstructure in chronic pain: a tract-based spatial statistics study and a systematic review</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The pathophysiology of many chronic pain disorders is far from evident. MR imaging studies provid...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The pathophysiology of many chronic pain disorders is far from evident. MR imaging studies provided initial data indicating chronic pain might lead to changes in brain structure and function. These changes may contribute to cognitive and emotional impairment and maybe even to the chronification of pain. However, the evidence for pain-related changes in gray and white matter is inconclusive so far. Hence we investigated potential changes of white matter microstructure in 34 adults with chronic noncancer pain (&amp;gt; 1 year) and 34 sex- and age-matched healthy individuals using diffusion tensor imaging (DTI). Whole-brain tract-based spatial statistics (TBSS) analyses of fractional anisotropy, mode of diffusivity, mean diffusivity, axial diffusivity, and radial diffusivity did not show significant differences after correction for multiple comparisons. The volumes of subdivisons of the corpus callosum were not significantly different either. We also performed a systematic review of the ex...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="eb56a01c28a1e84d85fad68262e999e2" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:104128402,&quot;asset_id&quot;:104382968,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/104128402/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&st=MTczMjQwOTc1NCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="104382968"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="104382968"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 104382968; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=104382968]").text(description); $(".js-view-count[data-work-id=104382968]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 104382968; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='104382968']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 104382968, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "eb56a01c28a1e84d85fad68262e999e2" } } $('.js-work-strip[data-work-id=104382968]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":104382968,"title":"Diffusion tensor imaging of white matter microstructure in chronic pain: a tract-based spatial statistics study and a systematic review","translated_title":"","metadata":{"abstract":"The pathophysiology of many chronic pain disorders is far from evident. MR imaging studies provided initial data indicating chronic pain might lead to changes in brain structure and function. These changes may contribute to cognitive and emotional impairment and maybe even to the chronification of pain. However, the evidence for pain-related changes in gray and white matter is inconclusive so far. Hence we investigated potential changes of white matter microstructure in 34 adults with chronic noncancer pain (\u0026gt; 1 year) and 34 sex- and age-matched healthy individuals using diffusion tensor imaging (DTI). Whole-brain tract-based spatial statistics (TBSS) analyses of fractional anisotropy, mode of diffusivity, mean diffusivity, axial diffusivity, and radial diffusivity did not show significant differences after correction for multiple comparisons. The volumes of subdivisons of the corpus callosum were not significantly different either. We also performed a systematic review of the ex...","publisher":"Cold Spring Harbor Laboratory","publication_date":{"day":null,"month":null,"year":2020,"errors":{}}},"translated_abstract":"The pathophysiology of many chronic pain disorders is far from evident. MR imaging studies provided initial data indicating chronic pain might lead to changes in brain structure and function. These changes may contribute to cognitive and emotional impairment and maybe even to the chronification of pain. However, the evidence for pain-related changes in gray and white matter is inconclusive so far. Hence we investigated potential changes of white matter microstructure in 34 adults with chronic noncancer pain (\u0026gt; 1 year) and 34 sex- and age-matched healthy individuals using diffusion tensor imaging (DTI). Whole-brain tract-based spatial statistics (TBSS) analyses of fractional anisotropy, mode of diffusivity, mean diffusivity, axial diffusivity, and radial diffusivity did not show significant differences after correction for multiple comparisons. The volumes of subdivisons of the corpus callosum were not significantly different either. 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The aims of the present study were twofold: using task-based functional MRI in a group of 17 healthy young participants, we studied (1) potential differences in the cerebral control of frontal, horizontal, and vertical tongue movements and (2) potential inter-individual differences in tongue motor control. To investigate differences between different tongue movements, we performed voxel-wise multiple linear regressions. To investigate inter-individual differences, we applied a novel approach, spatio-temporal filtering of independent components. For this approach, individual functional data sets were decomposed into spatially independent components and corresponding time courses using ICA. A temporal filter (correlation with the expected brain response) was used to identify independent components time-locked to the tongue motor task. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="89204522"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/89204522/Hyperactivity_restlessness_is_associated_with_increased_functional_connectivity_in_adults_with_ADHD_a_dimensional_analysis_of_resting_state_fMRI"><img alt="Research paper thumbnail of Hyperactivity/restlessness is associated with increased functional connectivity in adults with ADHD: a dimensional analysis of resting state fMRI" class="work-thumbnail" src="https://attachments.academia-assets.com/93044967/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89204522/Hyperactivity_restlessness_is_associated_with_increased_functional_connectivity_in_adults_with_ADHD_a_dimensional_analysis_of_resting_state_fMRI">Hyperactivity/restlessness is associated with increased functional connectivity in adults with ADHD: a dimensional analysis of resting state fMRI</a></div><div class="wp-workCard_item"><span>BMC Psychiatry</span><span>, 2019</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="c074b12645d01361673ac1223c98fdae" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:93044967,&quot;asset_id&quot;:89204522,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/93044967/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="89204522"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="89204522"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 89204522; 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Several lines of evidence support the idea that ADHD is, in its core, a disorder of dysfunctional brain connectivity within and between several neurofunctional networks. The primary aim of this study was to investigate associations between the functional connectivity within resting state brain networks and the individual severity of core ADHD symptoms (inattention, hyperactivity, and impulsivity). Methods: Resting state functional magnetic resonance imaging (rs-fMRI) data of 38 methylphenidate-naïve adults with childhood-onset ADHD (20 women, mean age 40.5 years) were analyzed using independent component analysis (FSL's MELODIC) and FSL's dual regression technique. For motion correction, standard volume-realignment followed by independent component analysis-based automatic removal of motion artifacts (FSL's ICA-AROMA) were employed. To identify well-established brain networks, the independent components found in the ADHD group were correlated with brain networks previously found in healthy participants (Smith et al. PNAS 2009;106:13040-5). To investigate associations between functional connectivity and individual symptom severity, sex, and age, linear regressions were performed. Results: Decomposition of resting state brain activity of adults with ADHD resulted in similar resting state networks as previously described for healthy adults. No significant differences in functional connectivity were seen between women and men. Advanced age was associated with decreased functional connectivity in parts of the bilateral cingulate and paracingulate cortex within the executive control network. More severe hyperactivity was associated with increased functional connectivity in the left putamen, right caudate nucleus, right central operculum and a portion of the right postcentral gyrus within the auditory/sensorimotor network. Conclusions: The present study supports and extends our knowledge on the involvement of the striatum in the pathophysiology of ADHD, in particular, in the pathogenesis of hyperactivity. Our results emphasize the usefulness of dimensional analyses in the study of ADHD, a highly heterogeneous disorder. Trial registration: ISRCTN12722296 (","publication_date":{"day":null,"month":null,"year":2019,"errors":{}},"publication_name":"BMC 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disorder","url":"https://www.academia.edu/Documents/in/Attention_deficit_hyperactivity_disorder-1"}],"urls":[{"id":25141409,"url":"http://link.springer.com/content/pdf/10.1186/s12888-019-2031-9.pdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="89204521"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/89204521/The_Senses_of_Agency_and_Ownership_A_Review"><img alt="Research paper thumbnail of The Senses of Agency and Ownership: A Review" class="work-thumbnail" src="https://attachments.academia-assets.com/93044999/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89204521/The_Senses_of_Agency_and_Ownership_A_Review">The Senses of Agency and Ownership: A Review</a></div><div class="wp-workCard_item"><span>Frontiers in psychology</span><span>, 2018</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Usually, we do not question that we possess a body and act upon the world. This pre-reflective aw...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Usually, we do not question that we possess a body and act upon the world. This pre-reflective awareness of being a bodily and agentive self can, however, be disrupted by different clinical conditions. Whereas sense of ownership (SoO) describes the feeling of mineness toward one&amp;#39;s own body parts, feelings or thoughts, sense of agency (SoA) refers to the experience of initiating and controlling an action. Although SoA and SoO naturally coincide, both experiences can also be made in isolation. By using many different experimental paradigms, both experiences have been extensively studied over the last years. This review introduces both concepts, with a special focus also onto their interplay. First, current experimental paradigms, results and neurocognitive theories about both concepts will be presented and then their clinical and therapeutic relevance is discussed.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="c5935c469a87a84107792be907df1078" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:93044999,&quot;asset_id&quot;:89204521,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/93044999/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="89204521"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="89204521"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 89204521; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=89204521]").text(description); $(".js-view-count[data-work-id=89204521]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 89204521; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='89204521']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 89204521, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "c5935c469a87a84107792be907df1078" } } $('.js-work-strip[data-work-id=89204521]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":89204521,"title":"The Senses of Agency and Ownership: A Review","translated_title":"","metadata":{"abstract":"Usually, we do not question that we possess a body and act upon the world. This pre-reflective awareness of being a bodily and agentive self can, however, be disrupted by different clinical conditions. Whereas sense of ownership (SoO) describes the feeling of mineness toward one\u0026#39;s own body parts, feelings or thoughts, sense of agency (SoA) refers to the experience of initiating and controlling an action. Although SoA and SoO naturally coincide, both experiences can also be made in isolation. By using many different experimental paradigms, both experiences have been extensively studied over the last years. This review introduces both concepts, with a special focus also onto their interplay. First, current experimental paradigms, results and neurocognitive theories about both concepts will be presented and then their clinical and therapeutic relevance is discussed.","publication_date":{"day":null,"month":null,"year":2018,"errors":{}},"publication_name":"Frontiers in psychology"},"translated_abstract":"Usually, we do not question that we possess a body and act upon the world. This pre-reflective awareness of being a bodily and agentive self can, however, be disrupted by different clinical conditions. Whereas sense of ownership (SoO) describes the feeling of mineness toward one\u0026#39;s own body parts, feelings or thoughts, sense of agency (SoA) refers to the experience of initiating and controlling an action. Although SoA and SoO naturally coincide, both experiences can also be made in isolation. By using many different experimental paradigms, both experiences have been extensively studied over the last years. This review introduces both concepts, with a special focus also onto their interplay. First, current experimental paradigms, results and neurocognitive theories about both concepts will be presented and then their clinical and therapeutic relevance is discussed.","internal_url":"https://www.academia.edu/89204521/The_Senses_of_Agency_and_Ownership_A_Review","translated_internal_url":"","created_at":"2022-10-25T10:40:30.287-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":109814020,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":93044999,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93044999/thumbnails/1.jpg","file_name":"aa4cd9dae8d0daa687391242bcc0328c1a93.pdf","download_url":"https://www.academia.edu/attachments/93044999/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"The_Senses_of_Agency_and_Ownership_A_Rev.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93044999/aa4cd9dae8d0daa687391242bcc0328c1a93-libre.pdf?1666723076=\u0026response-content-disposition=attachment%3B+filename%3DThe_Senses_of_Agency_and_Ownership_A_Rev.pdf\u0026Expires=1732413355\u0026Signature=K3TFrOhHychq9-3RpPAUXZgt9sz2BrTcPb-rKxTgdLd-j8yIa-IEiORWbY0hO9V~--HxsG9bjw1NF7ZlRfz9RAEBsmtURNhN1DtgPlEE2h6zTzluafrlbGpe04AmXypIkUNAtm-2N3XqAsH1GiZe5d3h2s66ntnUhHAlS-GRIfkeZHJM9GMaGYXBOsJUMbAYeGYgWH-WCOM38MP8iabLXlmqh6M-sY-oOSnjcJLPtGN5391aUATJDcAwPq5c7ivM8WgFr9LXf8XbGeiurtDl8N5yc6v4CZs0rupce6pE5v5G7ZgjwwSOpONZnv2LgQ01hL1K7oFoP7X3tVFrvCwVLw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"The_Senses_of_Agency_and_Ownership_A_Review","translated_slug":"","page_count":17,"language":"en","content_type":"Work","owner":{"id":109814020,"first_name":"Peter","middle_initials":null,"last_name":"Sörös","page_name":"PeterSörös","domain_name":"uni-oldenburg","created_at":"2019-04-20T13:40:00.221-07:00","display_name":"Peter Sörös","url":"https://uni-oldenburg.academia.edu/PeterS%C3%B6r%C3%B6s"},"attachments":[{"id":93044999,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93044999/thumbnails/1.jpg","file_name":"aa4cd9dae8d0daa687391242bcc0328c1a93.pdf","download_url":"https://www.academia.edu/attachments/93044999/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"The_Senses_of_Agency_and_Ownership_A_Rev.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93044999/aa4cd9dae8d0daa687391242bcc0328c1a93-libre.pdf?1666723076=\u0026response-content-disposition=attachment%3B+filename%3DThe_Senses_of_Agency_and_Ownership_A_Rev.pdf\u0026Expires=1732413355\u0026Signature=K3TFrOhHychq9-3RpPAUXZgt9sz2BrTcPb-rKxTgdLd-j8yIa-IEiORWbY0hO9V~--HxsG9bjw1NF7ZlRfz9RAEBsmtURNhN1DtgPlEE2h6zTzluafrlbGpe04AmXypIkUNAtm-2N3XqAsH1GiZe5d3h2s66ntnUhHAlS-GRIfkeZHJM9GMaGYXBOsJUMbAYeGYgWH-WCOM38MP8iabLXlmqh6M-sY-oOSnjcJLPtGN5391aUATJDcAwPq5c7ivM8WgFr9LXf8XbGeiurtDl8N5yc6v4CZs0rupce6pE5v5G7ZgjwwSOpONZnv2LgQ01hL1K7oFoP7X3tVFrvCwVLw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology"},{"id":817,"name":"Philosophy of Agency","url":"https://www.academia.edu/Documents/in/Philosophy_of_Agency"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":38781,"name":"Sense of agency","url":"https://www.academia.edu/Documents/in/Sense_of_agency"},{"id":51861,"name":"Neurocognitive","url":"https://www.academia.edu/Documents/in/Neurocognitive"},{"id":180133,"name":"Feeling","url":"https://www.academia.edu/Documents/in/Feeling"},{"id":2498386,"name":"Frontiers in Psychology","url":"https://www.academia.edu/Documents/in/Frontiers_in_Psychology"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="89204520"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/89204520/Synthetic_Cannabinoid_Use_in_a_Psychiatric_Patient_Population_A_Pilot_Study"><img alt="Research paper thumbnail of Synthetic Cannabinoid Use in a Psychiatric Patient Population: A Pilot Study" class="work-thumbnail" src="https://attachments.academia-assets.com/93045032/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89204520/Synthetic_Cannabinoid_Use_in_a_Psychiatric_Patient_Population_A_Pilot_Study">Synthetic Cannabinoid Use in a Psychiatric Patient Population: A Pilot Study</a></div><div class="wp-workCard_item"><span>European Addiction Research</span><span>, 2017</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background: Consumption of natural cannabis (NC) and synthetic cannabinoids (SCs) has been associ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background: Consumption of natural cannabis (NC) and synthetic cannabinoids (SCs) has been associated with psychotic disorders. We compared the prevalence of use, consumer profiles, and psychosis-inducing potential of NC and SCs in a specific high-risk population. Methods: This prospective pilot study included 332 patients (18-64 years, mean 36.83, SD 13.33). Patients&amp;#39; sociodemographics and medical histories as well as illicit substance use and psychiatric symptom histories were collected using a drug consumption survey that assessed the use of new psychoactive substances and the Psychotic Symptoms Interview. Results: In total, 7.2% of all patients, 10.6% of psychotic patients, and 4.5% of nonpsychotic patients reported SC consumption. Compared with SCs, NC was consumed much more frequently by its users (mean 222.73, SD 498.27). NC and SC use induced persistent psychosis. Psychotic symptoms were first experienced by patients with a history of NC or SC use during intoxication and...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="5dd295f3be7a560b94be8c79252ca077" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:93045032,&quot;asset_id&quot;:89204520,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/93045032/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="89204520"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="89204520"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 89204520; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=89204520]").text(description); $(".js-view-count[data-work-id=89204520]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 89204520; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='89204520']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 89204520, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "5dd295f3be7a560b94be8c79252ca077" } } $('.js-work-strip[data-work-id=89204520]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":89204520,"title":"Synthetic Cannabinoid Use in a Psychiatric Patient Population: A Pilot Study","translated_title":"","metadata":{"abstract":"Background: Consumption of natural cannabis (NC) and synthetic cannabinoids (SCs) has been associated with psychotic disorders. We compared the prevalence of use, consumer profiles, and psychosis-inducing potential of NC and SCs in a specific high-risk population. Methods: This prospective pilot study included 332 patients (18-64 years, mean 36.83, SD 13.33). Patients\u0026#39; sociodemographics and medical histories as well as illicit substance use and psychiatric symptom histories were collected using a drug consumption survey that assessed the use of new psychoactive substances and the Psychotic Symptoms Interview. Results: In total, 7.2% of all patients, 10.6% of psychotic patients, and 4.5% of nonpsychotic patients reported SC consumption. Compared with SCs, NC was consumed much more frequently by its users (mean 222.73, SD 498.27). NC and SC use induced persistent psychosis. Psychotic symptoms were first experienced by patients with a history of NC or SC use during intoxication and...","publisher":"S. Karger AG","publication_date":{"day":null,"month":null,"year":2017,"errors":{}},"publication_name":"European Addiction Research"},"translated_abstract":"Background: Consumption of natural cannabis (NC) and synthetic cannabinoids (SCs) has been associated with psychotic disorders. We compared the prevalence of use, consumer profiles, and psychosis-inducing potential of NC and SCs in a specific high-risk population. Methods: This prospective pilot study included 332 patients (18-64 years, mean 36.83, SD 13.33). Patients\u0026#39; sociodemographics and medical histories as well as illicit substance use and psychiatric symptom histories were collected using a drug consumption survey that assessed the use of new psychoactive substances and the Psychotic Symptoms Interview. Results: In total, 7.2% of all patients, 10.6% of psychotic patients, and 4.5% of nonpsychotic patients reported SC consumption. Compared with SCs, NC was consumed much more frequently by its users (mean 222.73, SD 498.27). NC and SC use induced persistent psychosis. Psychotic symptoms were first experienced by patients with a history of NC or SC use during intoxication and...","internal_url":"https://www.academia.edu/89204520/Synthetic_Cannabinoid_Use_in_a_Psychiatric_Patient_Population_A_Pilot_Study","translated_internal_url":"","created_at":"2022-10-25T10:40:29.980-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":109814020,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":93045032,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93045032/thumbnails/1.jpg","file_name":"EAR479554.pdf","download_url":"https://www.academia.edu/attachments/93045032/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Synthetic_Cannabinoid_Use_in_a_Psychiatr.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93045032/EAR479554-libre.pdf?1666723070=\u0026response-content-disposition=attachment%3B+filename%3DSynthetic_Cannabinoid_Use_in_a_Psychiatr.pdf\u0026Expires=1732413355\u0026Signature=UyKlgfKOXtjFxydxRha9vKsEKfCx-Gm-b~~XqrTvdmiOH7xoliro~DDvuXERq~QziX5r9ykft5EdkViwWa4NqzChMqt6-AUXxwxMyw2AtBeJ26j9hRuuW2TOz0Zz79uaay2HykKYB6LZuMWWfj23Nbf5VxSYigSPxKqgWx9ybhp-yN1Z641jzvtNDbCGH-q9zBICQSJ2fcPBeiSMsfV7zlur8PuXDZ3nCN2ctHuumoo-NJZNpv8g~jBKWb6QULzO~ghTuNxKgt9EFAulNokSN0DOAnPEnE1XoqdcDnh62jTzyA4GuXf3BwMLBe98zimLJ11qcW69-Zv1JhTaU63m2A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Synthetic_Cannabinoid_Use_in_a_Psychiatric_Patient_Population_A_Pilot_Study","translated_slug":"","page_count":12,"language":"en","content_type":"Work","owner":{"id":109814020,"first_name":"Peter","middle_initials":null,"last_name":"Sörös","page_name":"PeterSörös","domain_name":"uni-oldenburg","created_at":"2019-04-20T13:40:00.221-07:00","display_name":"Peter Sörös","url":"https://uni-oldenburg.academia.edu/PeterS%C3%B6r%C3%B6s"},"attachments":[{"id":93045032,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93045032/thumbnails/1.jpg","file_name":"EAR479554.pdf","download_url":"https://www.academia.edu/attachments/93045032/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Synthetic_Cannabinoid_Use_in_a_Psychiatr.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93045032/EAR479554-libre.pdf?1666723070=\u0026response-content-disposition=attachment%3B+filename%3DSynthetic_Cannabinoid_Use_in_a_Psychiatr.pdf\u0026Expires=1732413355\u0026Signature=UyKlgfKOXtjFxydxRha9vKsEKfCx-Gm-b~~XqrTvdmiOH7xoliro~DDvuXERq~QziX5r9ykft5EdkViwWa4NqzChMqt6-AUXxwxMyw2AtBeJ26j9hRuuW2TOz0Zz79uaay2HykKYB6LZuMWWfj23Nbf5VxSYigSPxKqgWx9ybhp-yN1Z641jzvtNDbCGH-q9zBICQSJ2fcPBeiSMsfV7zlur8PuXDZ3nCN2ctHuumoo-NJZNpv8g~jBKWb6QULzO~ghTuNxKgt9EFAulNokSN0DOAnPEnE1XoqdcDnh62jTzyA4GuXf3BwMLBe98zimLJ11qcW69-Zv1JhTaU63m2A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology"},{"id":635,"name":"Psychiatry","url":"https://www.academia.edu/Documents/in/Psychiatry"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":41788,"name":"Cannabinoids","url":"https://www.academia.edu/Documents/in/Cannabinoids"},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male"},{"id":238724,"name":"Cannabis","url":"https://www.academia.edu/Documents/in/Cannabis"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1"},{"id":562842,"name":"Psychiatric Hospitals","url":"https://www.academia.edu/Documents/in/Psychiatric_Hospitals"},{"id":612870,"name":"Psychotic Disorders","url":"https://www.academia.edu/Documents/in/Psychotic_Disorders"},{"id":945595,"name":"Pilot Projects","url":"https://www.academia.edu/Documents/in/Pilot_Projects"},{"id":1423077,"name":"Substance-Related Disorders","url":"https://www.academia.edu/Documents/in/Substance-Related_Disorders"},{"id":1907321,"name":"Marijuana abuse","url":"https://www.academia.edu/Documents/in/Marijuana_abuse"},{"id":2922956,"name":"Psychology and Cognitive Sciences","url":"https://www.academia.edu/Documents/in/Psychology_and_Cognitive_Sciences"},{"id":3763225,"name":"Medical and Health Sciences","url":"https://www.academia.edu/Documents/in/Medical_and_Health_Sciences"}],"urls":[{"id":25141408,"url":"https://www.karger.com/Article/Pdf/479554"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="89204519"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/89204519/Inattention_Predicts_Increased_Thickness_of_Left_Occipital_Cortex_in_Men_with_Attention_Deficit_Hyperactivity_Disorder"><img alt="Research paper thumbnail of Inattention Predicts Increased Thickness of Left Occipital Cortex in Men with Attention-Deficit/Hyperactivity Disorder" class="work-thumbnail" src="https://attachments.academia-assets.com/93045022/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89204519/Inattention_Predicts_Increased_Thickness_of_Left_Occipital_Cortex_in_Men_with_Attention_Deficit_Hyperactivity_Disorder">Inattention Predicts Increased Thickness of Left Occipital Cortex in Men with Attention-Deficit/Hyperactivity Disorder</a></div><div class="wp-workCard_item"><span>Frontiers in Psychiatry</span><span>, 2017</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="36ce105d275db48f5200483d5bb606de" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:93045022,&quot;asset_id&quot;:89204519,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/93045022/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="89204519"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="89204519"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 89204519; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=89204519]").text(description); $(".js-view-count[data-work-id=89204519]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 89204519; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='89204519']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 89204519, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "36ce105d275db48f5200483d5bb606de" } } $('.js-work-strip[data-work-id=89204519]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":89204519,"title":"Inattention Predicts Increased Thickness of Left Occipital Cortex in Men with Attention-Deficit/Hyperactivity Disorder","translated_title":"","metadata":{"publisher":"Frontiers Media SA","grobid_abstract":"Background: Attention-deficit/hyperactivity disorder (ADHD) in adulthood is a serious and frequent psychiatric disorder with the core symptoms inattention, impulsivity, and hyperactivity. The principal aim of this study was to investigate associations between brain morphology, i.e., cortical thickness and volumes of subcortical gray matter, and individual symptom severity in adult ADHD. Methods: Surface-based brain morphometry was performed in 35 women and 29 men with ADHD using FreeSurfer. Linear regressions were calculated between cortical thickness and the volumes of subcortical gray matter and the inattention, hyperactivity, and impulsivity subscales of the Conners Adult ADHD Rating Scales (CAARS). Two separate analyses were performed. For the first analysis, age was included as additional regressor. For the second analysis, both age and severity of depression were included as additional regressors. Study participants were recruited between June 2012 and January 2014. results: Linear regression identified an area in the left occipital cortex of men, covering parts of the middle occipital sulcus and gyrus, in which the score on the CAARS inattention subscale predicted increased mean cortical thickness [F(1,27) = 26.27, p \u003c 0.001, adjusted R 2 = 0.4744]. No significant associations were found between cortical thickness and the scores on CAARS subscales in women. No significant associations were found between the volumes of subcortical gray matter and the scores on CAARS subscales, neither in men nor in women. These results remained stable when severity of depression was included as additional regressor, together with age. conclusion: Increased cortical thickness in the left occipital cortex may represent a mechanism to compensate for dysfunctional attentional networks in male adult ADHD patients.","publication_date":{"day":null,"month":null,"year":2017,"errors":{}},"publication_name":"Frontiers in Psychiatry","grobid_abstract_attachment_id":93045022},"translated_abstract":null,"internal_url":"https://www.academia.edu/89204519/Inattention_Predicts_Increased_Thickness_of_Left_Occipital_Cortex_in_Men_with_Attention_Deficit_Hyperactivity_Disorder","translated_internal_url":"","created_at":"2022-10-25T10:40:29.213-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":109814020,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":93045022,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93045022/thumbnails/1.jpg","file_name":"85ebc0bace6123dcae8dac1ab6636acb788b.pdf","download_url":"https://www.academia.edu/attachments/93045022/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Inattention_Predicts_Increased_Thickness.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93045022/85ebc0bace6123dcae8dac1ab6636acb788b-libre.pdf?1666723075=\u0026response-content-disposition=attachment%3B+filename%3DInattention_Predicts_Increased_Thickness.pdf\u0026Expires=1732413355\u0026Signature=T7YOLT2Qto4MWOLoYFSgdDRWkSjgD6q1uOb22iPrhJcdfuxqpVl6V2HyxnPKTMg00GU8m-egd0jnK46i5wXYteiBh8OdyCLaBs6HaBSOJ6Yn21OpVQ~zEcA92M56PTmleb2oD-FT65ybnPhC5cIJH21ozx1ZfHWRSiEwWKvDKmCd3p7ruHbxfbog8nPHL2bpHCaygfHzGf6WTuo-91re9MF0Wn9hIY3bSfSsWdp7nCAByDNRJlcgcjZLqnPM8HhkYDhj2BZsCNm3oKXfD482LZpjTqtt~D8NmdXOEHccY84qTyjeiFdwHLmXqP38PVITWkcLZRtmOYDyy9dBf9w1aw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Inattention_Predicts_Increased_Thickness_of_Left_Occipital_Cortex_in_Men_with_Attention_Deficit_Hyperactivity_Disorder","translated_slug":"","page_count":11,"language":"en","content_type":"Work","owner":{"id":109814020,"first_name":"Peter","middle_initials":null,"last_name":"Sörös","page_name":"PeterSörös","domain_name":"uni-oldenburg","created_at":"2019-04-20T13:40:00.221-07:00","display_name":"Peter Sörös","url":"https://uni-oldenburg.academia.edu/PeterS%C3%B6r%C3%B6s"},"attachments":[{"id":93045022,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93045022/thumbnails/1.jpg","file_name":"85ebc0bace6123dcae8dac1ab6636acb788b.pdf","download_url":"https://www.academia.edu/attachments/93045022/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Inattention_Predicts_Increased_Thickness.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93045022/85ebc0bace6123dcae8dac1ab6636acb788b-libre.pdf?1666723075=\u0026response-content-disposition=attachment%3B+filename%3DInattention_Predicts_Increased_Thickness.pdf\u0026Expires=1732413355\u0026Signature=T7YOLT2Qto4MWOLoYFSgdDRWkSjgD6q1uOb22iPrhJcdfuxqpVl6V2HyxnPKTMg00GU8m-egd0jnK46i5wXYteiBh8OdyCLaBs6HaBSOJ6Yn21OpVQ~zEcA92M56PTmleb2oD-FT65ybnPhC5cIJH21ozx1ZfHWRSiEwWKvDKmCd3p7ruHbxfbog8nPHL2bpHCaygfHzGf6WTuo-91re9MF0Wn9hIY3bSfSsWdp7nCAByDNRJlcgcjZLqnPM8HhkYDhj2BZsCNm3oKXfD482LZpjTqtt~D8NmdXOEHccY84qTyjeiFdwHLmXqP38PVITWkcLZRtmOYDyy9dBf9w1aw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology"},{"id":8928,"name":"MRI","url":"https://www.academia.edu/Documents/in/MRI"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":2754641,"name":"Attention deficit hyperactivity disorder","url":"https://www.academia.edu/Documents/in/Attention_deficit_hyperactivity_disorder-1"}],"urls":[{"id":25141407,"url":"http://journal.frontiersin.org/article/10.3389/fpsyt.2017.00170/full"}]}, dispatcherData: dispatcherData }); 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Slow (2-6Hz) and beta (14-3OHz) activity were monitored up to 10 weeks. Results were compared with normative data, and changes over time were statistically analyzed. MEG detected pathological activity that persisted clinical symptoms. Focal slow activity originating from sensorimotor (TIA) and mesiotemporal (TGA) cortices exceeded normal values up to 14 times during the first hours after the attack and recovered to normal within 11 days. Focal beta activity was not useful to monitor the tinne course of TIA or 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$a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="89204516"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/89204516/The_neurochemical_basis_of_human_cortical_auditory_processing_combining_proton_magnetic_resonance_spectroscopy_and_magnetoencephalography"><img alt="Research paper thumbnail of The neurochemical basis of human cortical auditory processing: combining proton magnetic resonance spectroscopy and magnetoencephalography" class="work-thumbnail" src="https://attachments.academia-assets.com/93045061/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89204516/The_neurochemical_basis_of_human_cortical_auditory_processing_combining_proton_magnetic_resonance_spectroscopy_and_magnetoencephalography">The neurochemical basis of human cortical auditory processing: combining proton magnetic resonance spectroscopy and magnetoencephalography</a></div><div class="wp-workCard_item"><span>Bmc Biology</span><span>, 2006</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="f1373a5b7d992f249c720b4256382ca4" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:93045061,&quot;asset_id&quot;:89204516,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/93045061/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa 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})(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "f1373a5b7d992f249c720b4256382ca4" } } $('.js-work-strip[data-work-id=89204516]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":89204516,"title":"The neurochemical basis of human cortical auditory processing: combining proton magnetic resonance spectroscopy and magnetoencephalography","translated_title":"","metadata":{"grobid_abstract":"Background: A combination of magnetoencephalography and proton magnetic resonance spectroscopy was used to correlate the electrophysiology of rapid auditory processing and the neurochemistry of the auditory cortex in 15 healthy adults. To assess rapid auditory processing in the left auditory cortex, the amplitude and decrement of the N1m peak, the major component of the late auditory evoked response, were measured during rapidly successive presentation of acoustic stimuli. We tested the hypothesis that: (i) the amplitude of the N1m response and (ii) its decrement during rapid stimulation are associated with the cortical neurochemistry as determined by proton magnetic resonance spectroscopy. Results: Our results demonstrated a significant association between the concentrations of Nacetylaspartate, a marker of neuronal integrity, and the amplitudes of individual N1m responses. In addition, the concentrations of choline-containing compounds, representing the functional integrity of membranes, were significantly associated with N1m amplitudes. No significant association was found between the concentrations of the glutamate/glutamine pool and the amplitudes of the first N1m. No significant associations were seen between the decrement of the N1m (the relative amplitude of the second N1m peak) and the concentrations of N-acetylaspartate, cholinecontaining compounds, or the glutamate/glutamine pool. However, there was a trend for higher glutamate/glutamine concentrations in individuals with higher relative N1m amplitude. Conclusion: These results suggest that neuronal and membrane functions are important for rapid auditory processing. This investigation provides a first link between the electrophysiology, as recorded by magnetoencephalography, and the neurochemistry, as assessed by proton magnetic resonance spectroscopy, of the auditory cortex. Background Hearing is one of the fundamental and most important abilities of the vertebrate nervous system. The neurophysiology of the auditory system is increasingly well under","publication_date":{"day":null,"month":null,"year":2006,"errors":{}},"publication_name":"Bmc Biology","grobid_abstract_attachment_id":93045061},"translated_abstract":null,"internal_url":"https://www.academia.edu/89204516/The_neurochemical_basis_of_human_cortical_auditory_processing_combining_proton_magnetic_resonance_spectroscopy_and_magnetoencephalography","translated_internal_url":"","created_at":"2022-10-25T10:40:28.525-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":109814020,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":93045061,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93045061/thumbnails/1.jpg","file_name":"1741-7007-4-25.pdf","download_url":"https://www.academia.edu/attachments/93045061/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"The_neurochemical_basis_of_human_cortica.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93045061/1741-7007-4-25-libre.pdf?1666723066=\u0026response-content-disposition=attachment%3B+filename%3DThe_neurochemical_basis_of_human_cortica.pdf\u0026Expires=1732413355\u0026Signature=g2rw1mwHas5ZxbS6cVh13z3YISmSS6a55c6lrOntenmWLdVLsu59kqUUJMz~3gCeK-Wk-F2KvqBJBBeC48vIhigwcf0WS8mGqulKXOFfhYBM3CjtEwEeuYMVfvpOnNFCz8uSn-XiFigJXftMEQZqX9xZP9MrrtttSh7K9Fr2SCAlo52GfeVd9sAomkwx-GbZQiW~9nL~pIfw3wVCAJzjHfFDc-gEZPvlYyG3-egE~UBHwVwKDU~3QzKf3otkZ7bvCmTzhqx404WfHCZEHxt~HHdDY2Nh8O7EwoOXheyoXW0Olp6CtobV0IwZnwqyUjFhKGtlAjq6AvTeqRdd96~zwA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"The_neurochemical_basis_of_human_cortical_auditory_processing_combining_proton_magnetic_resonance_spectroscopy_and_magnetoencephalography","translated_slug":"","page_count":13,"language":"en","content_type":"Work","owner":{"id":109814020,"first_name":"Peter","middle_initials":null,"last_name":"Sörös","page_name":"PeterSörös","domain_name":"uni-oldenburg","created_at":"2019-04-20T13:40:00.221-07:00","display_name":"Peter 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Neuroscience","url":"https://www.academia.edu/Documents/in/Auditory_Neuroscience"},{"id":21732,"name":"Magnetic Resonance Spectroscopy","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Spectroscopy"},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent"},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":67688,"name":"Auditory temporal processing","url":"https://www.academia.edu/Documents/in/Auditory_temporal_processing"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":382341,"name":"Glutamine","url":"https://www.academia.edu/Documents/in/Glutamine"},{"id":546419,"name":"Age Factors","url":"https://www.academia.edu/Documents/in/Age_Factors"},{"id":723371,"name":"Auditory Cortex","url":"https://www.academia.edu/Documents/in/Auditory_Cortex"},{"id":990296,"name":"Choline","url":"https://www.academia.edu/Documents/in/Choline"},{"id":1292998,"name":"Glutamic Acid","url":"https://www.academia.edu/Documents/in/Glutamic_Acid"},{"id":2012816,"name":"Glutamate 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wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89204515/fMRI_compatible_registration_of_jaw_movements_using_a_fiber_optic_bend_sensor">fMRI-compatible registration of jaw movements using a fiber-optic bend sensor</a></div><div class="wp-workCard_item"><span>Frontiers in Human Neuroscience</span><span>, 2010</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="e254798058100ca71b11276afdd55a00" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:93045007,&quot;asset_id&quot;:89204515,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/93045007/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa 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})(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "e254798058100ca71b11276afdd55a00" } } $('.js-work-strip[data-work-id=89204515]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":89204515,"title":"fMRI-compatible registration of jaw movements using a fiber-optic bend sensor","translated_title":"","metadata":{"grobid_abstract":"To study speech-related movements outside MRI systems, surface electromyography (EMG) is widely used (Smith, 1992). In positron emission tomography (Murphy et al., 1997) and magnetoencephalography (Sörös et al., 2003), EMG has also been used frequently and successfully to monitor muscle function associated with overt speech production. The use of EMG in fMRI studies, however, is challenging (for a recent review on the recording of electrophysiological data during fMRI, see Laufs et al., 2008). Time-varying radiofrequency pulses and magnetic fi eld gradients may induce artifacts in EMG recordings and, conversely, movements of EMG electrodes and leads inside the magnetic fi eld may cause artifacts in fMRI data (Ganesh et al., 2007; MacIntosh et al., 2007). In addition, the use of EMG in an fMRI study is limited by the need of an fMRI-compatible EMG system (e.g., BrainAmp, Brain Products, Gilching, Germany 1), specialized EMG data postprocessing (van Duinen et al., 2005; MacIntosh et al., 2007), and by time constraints. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="89204513"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/89204513/Phantom_sensations_following_acute_pain"><img alt="Research paper thumbnail of Phantom sensations following acute pain" class="work-thumbnail" src="https://attachments.academia-assets.com/93045023/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89204513/Phantom_sensations_following_acute_pain">Phantom sensations following acute pain</a></div><div class="wp-workCard_item"><span>Pain</span><span>, 1998</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="2ea14000e206b08d3547f613ca0fcb0b" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:93045023,&quot;asset_id&quot;:89204513,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/93045023/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="89204513"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="89204513"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 89204513; 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A similar phenomenon was incidentally encountered in healthy subjects. For reasons unrelated to the question of mislocalization, we performed a study involving the application of experimental acute pain to the hand followed by non-noxious tactile stimulation of the ipsilateral lip. During lip stimulation, two out of six subjects spontaneously reported perceiving an additional phantom-like sensation in the hand synchronously to the non-noxious lip stimulation. Similar, although more diffuse, phantom sensations were observed in two out of seven additional subjects who were then tested specifically for this effect. The observation is compatible with a pain-induced hyperresponsiveness of the cortical hand area to somatotopically adjacent inputs from the lip. This suggests that, even in the absence of deafferentation, pain can lead to a representational reorganization.","publication_date":{"day":null,"month":null,"year":1998,"errors":{}},"publication_name":"Pain","grobid_abstract_attachment_id":93045023},"translated_abstract":null,"internal_url":"https://www.academia.edu/89204513/Phantom_sensations_following_acute_pain","translated_internal_url":"","created_at":"2022-10-25T10:40:27.807-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":109814020,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":93045023,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93045023/thumbnails/1.jpg","file_name":"s0304-3959_2898_2900102-x20221025-1-11q34lf.pdf","download_url":"https://www.academia.edu/attachments/93045023/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Phantom_sensations_following_acute_pain.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93045023/s0304-3959_2898_2900102-x20221025-1-11q34lf-libre.pdf?1666723069=\u0026response-content-disposition=attachment%3B+filename%3DPhantom_sensations_following_acute_pain.pdf\u0026Expires=1732413355\u0026Signature=Uvt8tyduBxtb-HQZ3KlZ6gQE0ZTYeYA1AbUpfAAYLxtywObSJmpemwEyblnGbTfmhe0-N14EsqXHizFaLGeFoNXMHs2m1jq6kMcGj4tZkj0LbKm1PYItJ0szz1dJ9JEMfc4L1YHVtvFtNk9e8oShxirXFKQCwb2QKfeDKzlyHP1WXVUbg8BFIrP6P2p1IbUhcq6vPikA8r08HqsGfjdtRCDQQCE5kRszdbKnDBwa-OAOFoKYxr1Qm3s3eQgBLm0rLuAQYEvE1v-VFwPEQ~aWihOVU1eAit8UQnsoo0ggOII9SroebhHuM-XHOKmGYUWxt6chSpnGxAp0940AFxJALA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Phantom_sensations_following_acute_pain","translated_slug":"","page_count":5,"language":"en","content_type":"Work","owner":{"id":109814020,"first_name":"Peter","middle_initials":null,"last_name":"Sörös","page_name":"PeterSörös","domain_name":"uni-oldenburg","created_at":"2019-04-20T13:40:00.221-07:00","display_name":"Peter Sörös","url":"https://uni-oldenburg.academia.edu/PeterS%C3%B6r%C3%B6s"},"attachments":[{"id":93045023,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93045023/thumbnails/1.jpg","file_name":"s0304-3959_2898_2900102-x20221025-1-11q34lf.pdf","download_url":"https://www.academia.edu/attachments/93045023/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Phantom_sensations_following_acute_pain.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93045023/s0304-3959_2898_2900102-x20221025-1-11q34lf-libre.pdf?1666723069=\u0026response-content-disposition=attachment%3B+filename%3DPhantom_sensations_following_acute_pain.pdf\u0026Expires=1732413355\u0026Signature=Uvt8tyduBxtb-HQZ3KlZ6gQE0ZTYeYA1AbUpfAAYLxtywObSJmpemwEyblnGbTfmhe0-N14EsqXHizFaLGeFoNXMHs2m1jq6kMcGj4tZkj0LbKm1PYItJ0szz1dJ9JEMfc4L1YHVtvFtNk9e8oShxirXFKQCwb2QKfeDKzlyHP1WXVUbg8BFIrP6P2p1IbUhcq6vPikA8r08HqsGfjdtRCDQQCE5kRszdbKnDBwa-OAOFoKYxr1Qm3s3eQgBLm0rLuAQYEvE1v-VFwPEQ~aWihOVU1eAit8UQnsoo0ggOII9SroebhHuM-XHOKmGYUWxt6chSpnGxAp0940AFxJALA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":2380,"name":"Plasticity","url":"https://www.academia.edu/Documents/in/Plasticity"},{"id":2898,"name":"Pain","url":"https://www.academia.edu/Documents/in/Pain"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":75075,"name":"Phantom limb","url":"https://www.academia.edu/Documents/in/Phantom_limb"},{"id":82660,"name":"Sensation","url":"https://www.academia.edu/Documents/in/Sensation"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male"},{"id":132020,"name":"Neuronal Plasticity","url":"https://www.academia.edu/Documents/in/Neuronal_Plasticity"},{"id":138306,"name":"Phantom Pain","url":"https://www.academia.edu/Documents/in/Phantom_Pain"},{"id":277717,"name":"Somatosensory Cortex","url":"https://www.academia.edu/Documents/in/Somatosensory_Cortex"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":541937,"name":"Stimulation","url":"https://www.academia.edu/Documents/in/Stimulation"},{"id":1142759,"name":"Healthy Subjects","url":"https://www.academia.edu/Documents/in/Healthy_Subjects"},{"id":2471455,"name":"Acute Disease","url":"https://www.academia.edu/Documents/in/Acute_Disease"},{"id":2922956,"name":"Psychology and Cognitive Sciences","url":"https://www.academia.edu/Documents/in/Psychology_and_Cognitive_Sciences"},{"id":3763225,"name":"Medical and Health Sciences","url":"https://www.academia.edu/Documents/in/Medical_and_Health_Sciences"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="89204512"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/89204512/A_Study_of_Brain_Networks_Associated_with_Swallowing_Using_Graph_Theoretical_Approaches"><img alt="Research paper thumbnail of A Study of Brain Networks Associated with Swallowing Using Graph-Theoretical Approaches" class="work-thumbnail" src="https://attachments.academia-assets.com/93045001/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89204512/A_Study_of_Brain_Networks_Associated_with_Swallowing_Using_Graph_Theoretical_Approaches">A Study of Brain Networks Associated with Swallowing Using Graph-Theoretical Approaches</a></div><div class="wp-workCard_item"><span>PLoS ONE</span><span>, 2013</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="cea575a6408b0df66dd2930260d045d3" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:93045001,&quot;asset_id&quot;:89204512,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/93045001/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="89204512"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="89204512"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 89204512; 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Understanding these complex interactions is of great interest from both a scientific and a clinical perspective. In this study, functional magnetic resonance imaging (fMRI) was utilized to study brain functional networks during voluntary saliva swallowing in twenty-two adult healthy subjects (all females, 23:1+1:52 years of age). To construct these functional connections, we computed mean partial correlation matrices over ninety brain regions for each participant. Two regions were determined to be functionally connected if their correlation was above a certain threshold. These correlation matrices were then analyzed using graphtheoretical approaches. In particular, we considered several network measures for the whole brain and for swallowingrelated brain regions. The results have shown that significant pairwise functional connections were, mostly, either local and intra-hemispheric or symmetrically inter-hemispheric. Furthermore, we showed that all human brain functional network, although varying in some degree, had typical small-world properties as compared to regular networks and random networks. These properties allow information transfer within the network at a relatively high efficiency. Swallowing-related brain regions also had higher values for some of the network measures in comparison to when these measures were calculated for the whole brain. The current results warrant further investigation of graph-theoretical approaches as a potential tool for understanding the neural basis of dysphagia.","publication_date":{"day":null,"month":null,"year":2013,"errors":{}},"publication_name":"PLoS ONE","grobid_abstract_attachment_id":93045001},"translated_abstract":null,"internal_url":"https://www.academia.edu/89204512/A_Study_of_Brain_Networks_Associated_with_Swallowing_Using_Graph_Theoretical_Approaches","translated_internal_url":"","created_at":"2022-10-25T10:40:27.317-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":109814020,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":93045001,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93045001/thumbnails/1.jpg","file_name":"5a812d80bec3f11e0fcb5528de0140941e11.pdf","download_url":"https://www.academia.edu/attachments/93045001/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"A_Study_of_Brain_Networks_Associated_wit.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93045001/5a812d80bec3f11e0fcb5528de0140941e11-libre.pdf?1666723075=\u0026response-content-disposition=attachment%3B+filename%3DA_Study_of_Brain_Networks_Associated_wit.pdf\u0026Expires=1732413355\u0026Signature=RsNmvI2g55LrQroQhbqNjCey4cUsTonbEuJJ07MhTqYgNi5PLD4JuulbXY4HQuCyq5-VuefYPeM9JM9LrNyPoUR35FOSc8RZJQY3VArfbKbujJ0wKTNnGga5c7RUiIwuTZKVs8Mey6gcLnvjVUv1hIFmMpfY7oX7MZsNF~0CbSTe~Lg6SueDg6Ixxo2jPDsaDPzGWEMTyHj5TCgd3YFP01PpahJ~IK4YC~b6axiYyqhBN4XC6DRCDVeZCl81nc~97s-KV7QyCTAFMS1Bh-fEfLxr7zrxru0HzAXYOxXNdUaWc3bBFffOZXcGid9ol9f4WjwfxGGImdWpySLT1A7nMg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"A_Study_of_Brain_Networks_Associated_with_Swallowing_Using_Graph_Theoretical_Approaches","translated_slug":"","page_count":11,"language":"en","content_type":"Work","owner":{"id":109814020,"first_name":"Peter","middle_initials":null,"last_name":"Sörös","page_name":"PeterSörös","domain_name":"uni-oldenburg","created_at":"2019-04-20T13:40:00.221-07:00","display_name":"Peter Sörös","url":"https://uni-oldenburg.academia.edu/PeterS%C3%B6r%C3%B6s"},"attachments":[{"id":93045001,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93045001/thumbnails/1.jpg","file_name":"5a812d80bec3f11e0fcb5528de0140941e11.pdf","download_url":"https://www.academia.edu/attachments/93045001/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"A_Study_of_Brain_Networks_Associated_wit.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93045001/5a812d80bec3f11e0fcb5528de0140941e11-libre.pdf?1666723075=\u0026response-content-disposition=attachment%3B+filename%3DA_Study_of_Brain_Networks_Associated_wit.pdf\u0026Expires=1732413355\u0026Signature=RsNmvI2g55LrQroQhbqNjCey4cUsTonbEuJJ07MhTqYgNi5PLD4JuulbXY4HQuCyq5-VuefYPeM9JM9LrNyPoUR35FOSc8RZJQY3VArfbKbujJ0wKTNnGga5c7RUiIwuTZKVs8Mey6gcLnvjVUv1hIFmMpfY7oX7MZsNF~0CbSTe~Lg6SueDg6Ixxo2jPDsaDPzGWEMTyHj5TCgd3YFP01PpahJ~IK4YC~b6axiYyqhBN4XC6DRCDVeZCl81nc~97s-KV7QyCTAFMS1Bh-fEfLxr7zrxru0HzAXYOxXNdUaWc3bBFffOZXcGid9ol9f4WjwfxGGImdWpySLT1A7nMg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":422,"name":"Computer Science","url":"https://www.academia.edu/Documents/in/Computer_Science"},{"id":428,"name":"Algorithms","url":"https://www.academia.edu/Documents/in/Algorithms"},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging"},{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":28235,"name":"Multidisciplinary","url":"https://www.academia.edu/Documents/in/Multidisciplinary"},{"id":52176,"name":"Brain Mapping","url":"https://www.academia.edu/Documents/in/Brain_Mapping"},{"id":61474,"name":"Brain","url":"https://www.academia.edu/Documents/in/Brain"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":82955,"name":"Swallowing","url":"https://www.academia.edu/Documents/in/Swallowing"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult"},{"id":220780,"name":"PLoS one","url":"https://www.academia.edu/Documents/in/PLoS_one"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":2444775,"name":"Psychomotor Performance","url":"https://www.academia.edu/Documents/in/Psychomotor_Performance"},{"id":3275398,"name":"Deglutition","url":"https://www.academia.edu/Documents/in/Deglutition"}],"urls":[{"id":25141406,"url":"http://dx.plos.org/10.1371/journal.pone.0073577"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="89204510"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/89204510/Current_source_density_distribution_of_sleep_spindles_in_humans_as_found_by_synthetic_aperture_magnetometry"><img alt="Research paper thumbnail of Current source density distribution of sleep spindles in humans as found by synthetic aperture magnetometry" class="work-thumbnail" src="https://attachments.academia-assets.com/93045015/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89204510/Current_source_density_distribution_of_sleep_spindles_in_humans_as_found_by_synthetic_aperture_magnetometry">Current source density distribution of sleep spindles in humans as found by synthetic aperture magnetometry</a></div><div class="wp-workCard_item"><span>Neuroscience Letters</span><span>, 2003</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="3a7df9152c69f4cec43924d22ad16244" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:93045015,&quot;asset_id&quot;:89204510,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/93045015/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="89204510"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="89204510"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 89204510; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=89204510]").text(description); $(".js-view-count[data-work-id=89204510]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 89204510; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='89204510']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 89204510, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "3a7df9152c69f4cec43924d22ad16244" } } $('.js-work-strip[data-work-id=89204510]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":89204510,"title":"Current source density distribution of sleep spindles in humans as found by synthetic aperture magnetometry","translated_title":"","metadata":{"publisher":"Elsevier BV","grobid_abstract":"Previous magnetoencephalography (MEG) studies of sleep spindles have identified a complex and widespread distribution in parietal and frontal cortices by fitting a dipolar model to the data. In this study, we used a whole-head 151-channel MEG system with simultaneous electroencephalography (EEG) recording in eight normal subjects. All subjects fell asleep during stage 2 and 3; EEG spindles have been observed in all cases. The current source density distribution of sleep spindles in the 10-15 Hz frequency band was localized by means of synthetic aperture magnetometry, and statistically tested using a permutation analysis. Source locations of the sleep spindles were found primarily in the frontal cortex, including dorsolateral and medial prefrontal areas, as well as the parietal cortex, including the vicinity of the primary sensorimotor areas. These results suggest that sleep spindles are similar in frequency content and spatial location to mu rhythm, and that these two oscillatory activities might also have a common neural basis and physiological meaning.","publication_date":{"day":null,"month":null,"year":2003,"errors":{}},"publication_name":"Neuroscience 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href="https://www.academia.edu/89204505/Altered_Habituation_in_the_Auditory_Cortex_in_a_Subgroup_of_Depressed_Patients_by_Functional_Magnetic_Resonance_Imaging"><img alt="Research paper thumbnail of Altered Habituation in the Auditory Cortex in a Subgroup of Depressed Patients by Functional Magnetic Resonance Imaging" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89204505/Altered_Habituation_in_the_Auditory_Cortex_in_a_Subgroup_of_Depressed_Patients_by_Functional_Magnetic_Resonance_Imaging">Altered Habituation in the Auditory Cortex in a Subgroup of Depressed Patients by Functional Magnetic Resonance Imaging</a></div><div class="wp-workCard_item"><span>Neuropsychobiology</span><span>, 2004</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The aim of this study was to measure and quantify habituation effects to auditory stimulation wit...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The aim of this study was to measure and quantify habituation effects to auditory stimulation within the auditory cortex of 11 depressed patients with major depressive disorder compared to 11 healthy subjects. Habituation was visualized by functional magnetic resonance imaging (fMRI) employing a block design (repeated stimulation with sine tones). A subgroup of patients (n = 5) presented the following abnormal habituation fMRI pattern: significantly lower activation after the first stimulation block (p = 0.05), missing characteristic signal decay to repeated acoustic stimulation and a marked undershoot after each stimulation block. This abnormal pattern may indicate functional deficits in auditory processing occurring with depression, but our results need be confirmed in a larger, more homogeneous patient group. This paradigm may be a useful tool for assessing cortical dysfunction in mood disorders.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="89204505"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="89204505"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 89204505; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=89204505]").text(description); $(".js-view-count[data-work-id=89204505]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 89204505; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='89204505']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 89204505, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=89204505]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":89204505,"title":"Altered Habituation in the Auditory Cortex in a Subgroup of Depressed Patients by Functional Magnetic Resonance Imaging","translated_title":"","metadata":{"abstract":"The aim of this study was to measure and quantify habituation effects to auditory stimulation within the auditory cortex of 11 depressed patients with major depressive disorder compared to 11 healthy subjects. Habituation was visualized by functional magnetic resonance imaging (fMRI) employing a block design (repeated stimulation with sine tones). A subgroup of patients (n = 5) presented the following abnormal habituation fMRI pattern: significantly lower activation after the first stimulation block (p = 0.05), missing characteristic signal decay to repeated acoustic stimulation and a marked undershoot after each stimulation block. This abnormal pattern may indicate functional deficits in auditory processing occurring with depression, but our results need be confirmed in a larger, more homogeneous patient group. This paradigm may be a useful tool for assessing cortical dysfunction in mood disorders.","publisher":"S. Karger AG","publication_date":{"day":null,"month":null,"year":2004,"errors":{}},"publication_name":"Neuropsychobiology"},"translated_abstract":"The aim of this study was to measure and quantify habituation effects to auditory stimulation within the auditory cortex of 11 depressed patients with major depressive disorder compared to 11 healthy subjects. Habituation was visualized by functional magnetic resonance imaging (fMRI) employing a block design (repeated stimulation with sine tones). A subgroup of patients (n = 5) presented the following abnormal habituation fMRI pattern: significantly lower activation after the first stimulation block (p = 0.05), missing characteristic signal decay to repeated acoustic stimulation and a marked undershoot after each stimulation block. This abnormal pattern may indicate functional deficits in auditory processing occurring with depression, but our results need be confirmed in a larger, more homogeneous patient group. This paradigm may be a useful tool for assessing cortical dysfunction in mood disorders.","internal_url":"https://www.academia.edu/89204505/Altered_Habituation_in_the_Auditory_Cortex_in_a_Subgroup_of_Depressed_Patients_by_Functional_Magnetic_Resonance_Imaging","translated_internal_url":"","created_at":"2022-10-25T10:40:26.261-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":109814020,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Altered_Habituation_in_the_Auditory_Cortex_in_a_Subgroup_of_Depressed_Patients_by_Functional_Magnetic_Resonance_Imaging","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":109814020,"first_name":"Peter","middle_initials":null,"last_name":"Sörös","page_name":"PeterSörös","domain_name":"uni-oldenburg","created_at":"2019-04-20T13:40:00.221-07:00","display_name":"Peter Sörös","url":"https://uni-oldenburg.academia.edu/PeterS%C3%B6r%C3%B6s"},"attachments":[],"research_interests":[{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science"},{"id":3217,"name":"Depression","url":"https://www.academia.edu/Documents/in/Depression"},{"id":4139,"name":"Audiology","url":"https://www.academia.edu/Documents/in/Audiology"},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging"},{"id":52176,"name":"Brain Mapping","url":"https://www.academia.edu/Documents/in/Brain_Mapping"},{"id":58520,"name":"Habituation","url":"https://www.academia.edu/Documents/in/Habituation"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":84318,"name":"Auditory Processing","url":"https://www.academia.edu/Documents/in/Auditory_Processing"},{"id":97765,"name":"Functional Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Functional_Magnetic_Resonance_Imaging"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":100946,"name":"Functional Imaging","url":"https://www.academia.edu/Documents/in/Functional_Imaging"},{"id":157943,"name":"Depressive Disorder","url":"https://www.academia.edu/Documents/in/Depressive_Disorder"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":723371,"name":"Auditory Cortex","url":"https://www.academia.edu/Documents/in/Auditory_Cortex"},{"id":1142759,"name":"Healthy Subjects","url":"https://www.academia.edu/Documents/in/Healthy_Subjects"},{"id":1236957,"name":"Block Design","url":"https://www.academia.edu/Documents/in/Block_Design"},{"id":1355489,"name":"Affective Disorder","url":"https://www.academia.edu/Documents/in/Affective_Disorder"},{"id":1819399,"name":"Case Control Studies","url":"https://www.academia.edu/Documents/in/Case_Control_Studies"},{"id":2428413,"name":"Acoustic Stimulation","url":"https://www.academia.edu/Documents/in/Acoustic_Stimulation"}],"urls":[{"id":25141402,"url":"https://www.karger.com/Article/Pdf/75331"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="89204502"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/89204502/Naming_actions_and_objects_cortical_dynamics_in_healthy_adults_and_in_an_anomic_patient_with_a_dissociation_in_action_object_naming"><img alt="Research paper thumbnail of Naming actions and objects: cortical dynamics in healthy adults and in an anomic patient with a dissociation in action/object naming" class="work-thumbnail" src="https://attachments.academia-assets.com/93045059/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89204502/Naming_actions_and_objects_cortical_dynamics_in_healthy_adults_and_in_an_anomic_patient_with_a_dissociation_in_action_object_naming">Naming actions and objects: cortical dynamics in healthy adults and in an anomic patient with a dissociation in action/object naming</a></div><div class="wp-workCard_item"><span>NeuroImage</span><span>, 2003</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="86012d3fa6c51624a7c72cc9110f7c4f" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:93045059,&quot;asset_id&quot;:89204502,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/93045059/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="89204502"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="89204502"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 89204502; 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These reports have been taken as evidence for separate representations of nouns and verbs in the human brain. We used whole-head magnetoencephalography to record cortical dynamics of action and object naming in 10 healthy adults and in 1 anomic patient with superior naming of verbs compared with nouns due to a left posterior parietal lesion. A single set of 100 line drawings was used for both action and object naming. In normal subjects, the activation sequences in action and object naming were essentially identical, advancing from the occipital to posterior temporoparietal and further to the left frontal cortex, without consistent involvement of the classical left inferior frontal (Broca) and temporal (Wernicke) language areas. In the anomic patient, pronounced differences between action and object naming emerged in the left hemisphere. The activation sequence was disrupted at the level of the damaged parietal cortex and did not reach the left frontal cortex even in the relatively easier action naming. The more severely impaired object naming was associated with exceptionally strong and early activation of the left inferior frontal cortex (Broca) and subsequent pronounced activation of the left middle temporal cortex, silent in action naming. Verb and noun retrieval thus utilized a spatiotemporally similar neuronal network in healthy individuals. A clear dissociation in cortical correlates of verb and noun retrieval only became evident in our anomic patient, in whom damage to the language network has resulted in disproportionately worse performance in object than action naming.","publication_date":{"day":null,"month":null,"year":2003,"errors":{}},"publication_name":"NeuroImage","grobid_abstract_attachment_id":93045059},"translated_abstract":null,"internal_url":"https://www.academia.edu/89204502/Naming_actions_and_objects_cortical_dynamics_in_healthy_adults_and_in_an_anomic_patient_with_a_dissociation_in_action_object_naming","translated_internal_url":"","created_at":"2022-10-25T10:40:25.952-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":109814020,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":93045059,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93045059/thumbnails/1.jpg","file_name":"s1053-8119_2803_2900217-920221025-1-1bkcm7r.pdf","download_url":"https://www.academia.edu/attachments/93045059/download_file?st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&st=MTczMjQwOTc1NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Naming_actions_and_objects_cortical_dyna.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93045059/s1053-8119_2803_2900217-920221025-1-1bkcm7r-libre.pdf?1666723068=\u0026response-content-disposition=attachment%3B+filename%3DNaming_actions_and_objects_cortical_dyna.pdf\u0026Expires=1732413355\u0026Signature=QY3EPphFnIUJ1VgCNimGSqfsjXUN6QiqPYjpen1E8TqjItzaFnslGE18rNbBoWhdDhTHQTuw9jIqQqEk3Mt-Kjt-Z4Y0nuAlUBNcykqqFjAWKTJT7EF3GpE-kihRyjdYylmvuVnluvEzf7Nl1oqR-8a~LyJlKlG-HTmNwleIcwNVppNuMKrW0qfa4xWBEr3b44MnJNXEubPYecQ3axEz40fAxArtuRnNMbd9rX-6kav16~rlOFV7ne1xl7q3ESCD0VMqQqRxDh5z~lhDU6VklR22N3FWUj3TNSHsbz~tRuGrTtVvaB3Gv4S3TlMrS28eL5NZ2fcVUhDYz01276sMYA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Naming_actions_and_objects_cortical_dynamics_in_healthy_adults_and_in_an_anomic_patient_with_a_dissociation_in_action_object_naming","translated_slug":"","page_count":15,"language":"en","content_type":"Work","owner":{"id":109814020,"first_name":"Peter","middle_initials":null,"last_name":"Sörös","page_name":"PeterSörös","domain_name":"uni-oldenburg","created_at":"2019-04-20T13:40:00.221-07:00","display_name":"Peter 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and Health Sciences","url":"https://www.academia.edu/Documents/in/Medical_and_Health_Sciences"},{"id":3981850,"name":"Language tests","url":"https://www.academia.edu/Documents/in/Language_tests"}],"urls":[{"id":25141399,"url":"https://api.elsevier.com/content/article/PII:S1053811903002179?httpAccept=text/xml"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="89204500"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/89204500/Time_course_of_focal_pathological_activity_in_TIA_and_TGA_investigated_by_magnetoencephalography"><img alt="Research paper thumbnail of Time course of focal pathological activity in TIA and TGA investigated by magnetoencephalography" class="work-thumbnail" src="https://attachments.academia-assets.com/93044998/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89204500/Time_course_of_focal_pathological_activity_in_TIA_and_TGA_investigated_by_magnetoencephalography">Time course of focal pathological activity in TIA and TGA investigated by magnetoencephalography</a></div><div class="wp-workCard_item"><span>NeuroImage</span><span>, 2000</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="f5fa857c1e31938e774ff78a46e76f1c" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" 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neuroanatomy of overt speech production" class="work-thumbnail" src="https://attachments.academia-assets.com/93045086/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89204498/Age_related_changes_in_the_functional_neuroanatomy_of_overt_speech_production">Age-related changes in the functional neuroanatomy of overt speech production</a></div><div class="wp-workCard_item"><span>Neurobiology of Aging</span><span>, 2011</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="d00b021543e8155192047132482cf8a5" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" 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healthy aging, resulting in behavioral deficits and changes in brain activity, have been described for cognitive, motor, and sensory functions. To investigate age-related changes in the neural circuitry underlying overt non-lexical speech production, functional MRI was performed in 14 healthy younger (21-32 years) and 14 healthy older individuals (62-84 years). The experimental task involved the acoustically cued overt production of the vowel /a/ and the polysyllabic utterance /pataka/. In younger and older individuals, overt speech production was associated with the activation of a widespread articulo-phonological network, including the primary motor cortex, the supplementary motor area, the cingulate motor areas, and the posterior superior temporal cortex, similar in the /a/ and /pataka/ condition. An analysis of variance with the factors age and condition revealed a significant main effect of age. Irrespective of the experimental condition, significantly greater activation was found in the bilateral posterior superior temporal cortex, the posterior temporal plane, and the transverse temporal gyri in younger compared to older individuals. Significantly greater activation was found in the bilateral middle temporal gyri, medial frontal gyri, middle frontal gyri, and inferior frontal gyri in older vs. younger individuals. The analysis of variance did not reveal a significant main effect of condition and no significant interaction of age and condition. 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