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Preventing Opioid Overdose | Overdose Prevention | CDC

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href="/overdose-prevention/manage-treat-pain/index.html" tabindex="0"> Management and Treatment of Pain </a> <a class="view-all" href="/overdose-prevention/site.html"> View All </a> </div> </div> </header> <main class="container cdc-main" role="main" aria-label="Main Content Area"> <section class="cdc-page-title-bar cdc-page-offset noindex"> <time class="cdc-page-title-bar__item cdc-page-title-bar__item--date" datetime="2024-05-08 04:00:00"> May 8, 2024 </time> </section> <div class="cdc-page-feature cdc-page-feature--ssi"></div> <div class="cdc-page-title cdc-page-offset syndicate"> <h1>Preventing Opioid Overdose</h1> </div> <div id="content" class="cdc-page-content cdc-page-offset syndicate container"> <div class="cdc-dfe-body "> <div class="cdc-dfe-body__top "> <div class="dfe-section dfe-section--page-summary summary-list" data-section="cdc_prevention_page_summary"> <div class="dfe-section__header"> <h2>What to know</h2> </div> <div class="dfe-section__content"> <ul class="nested-list"> <li class="level-1">Overdoses are the leading injury-related cause of death in the United States.<ul> </ul> </li> <li class="level-1">Opioids, mainly illegally made fentanyl, are involved in the highest percentage of overdose deaths.<ul> </ul> </li> <li class="level-1">Ways to prevent opioid overdose are to improve opioid prescribing, reduce exposure to opioids, prevent illegal opioid use and prescription opioid misuse, and treat opioid use disorder.<ul> </ul> </li> </ul> </div> <div id="nav-buttons"> </div> </div> </div> <div class="cdc-dfe-body__center "> <div class="dfe-section" data-section="cdc_prevention_overview"> <a class="onThisPageAnchor" id="cdc_prevention_overview-opioid-use-disorder-and-overdoses-are-preventable" name="Opioid%20use%20disorder%20and%20overdoses%20are%20preventable" title="Opioid use disorder and overdoses are preventable"><!-- --></a><h2>Opioid use disorder and overdoses are preventable</h2> <p><strong>When we act early, we can prevent illegal substance use, including illegal opioids, and misuse of prescription medications, like opioids, that can lead to substance use disorders.</strong></p> <p>Substance use disorders, like opioid use disorder (OUD), impact communities across America. Prevention activities help educate and support individuals, families, and communities and are critical for maintaining both individual and community health.</p> <p><strong><a href="https://www.cdc.gov/overdose-prevention/prevention/preventing-opioid-use-disorder.html">Opioid Use Disorder (OUD)</a></strong>, sometimes referred to as "opioid dependence" or "opioid addiction," is a problematic pattern of opioid use that causes significant impairment or distress. OUD is a medical condition that can affect anyone &ndash; regardless of race, gender, income level, or social class. Like many other medical conditions, evidence-based treatments are available for OUD, but seeking treatment remains stigmatized. Stigma can be a major barrier to how well prevention and treatment programs work amid the opioid crisis.</p> <div class="dfe-block dfe-callout dfe-callout--standard"><div class="dfe-callout__icon" role="presentation"></div> <h3>Keep in mind&lrm;</h3> <div class="dfe-callout__body"><div class="callout-desc"><strong>Stigma</strong> or the fear of stigma may stop someone from sharing their health condition with partners or family members. Stigma may come from a specific person, including a loved one or clinician, or from the larger community. People seeking treatment for OUD may find that some clinicians have stigmatizing attitudes about OUD. Stigmatizing attitudes toward people with OUD among clinicians can create barriers for those seeking the health services they need.<span class="cdc-references-cite"><a class="cdc-references-cite__link" href="#cdcreference_1" aria-label="Reference link 1">1</a></span> People who experience health-related stigma may also experience less access to treatment or reduced adherence to treatments.<span class="cdc-references-cite"><a class="cdc-references-cite__link" href="#cdcreference_2" aria-label="Reference link 2">2</a></span> Learn more about what you can do to <a href="/stop-overdose/stigma-reduction/index.html" class="ce-selection">reduce stigma</a>.</div> </div></div> <p>OUD significantly contributes to overdose deaths among people who use illegal opioids or misuse prescription opioids. Opioids&mdash;mainly synthetic opioids like illegally made fentanyl--are currently the most represented in overdose deaths.</p> <p>A recent <a href="/mmwr/volumes/72/wr/mm7235a3.htm">study</a> among 29 states and the District of Columbia showed the percentage of overdose deaths involving counterfeit pills <strong>more than doubled</strong> from July 2019 to December 2021, and <strong>more than tripled</strong> in the Western United States. These pills are dangerous because they typically appear as pharmaceutical pills but often contain illegally made fentanyl and illegal benzodiazepines or other drugs, with or without people's knowledge.</p> <p>For every overdose that results in death, there are many more nonfatal overdoses, each one with its own emotional and economic toll.<span class="cdc-references-cite"><a class="cdc-references-cite__link" href="#cdcreference_3" aria-label="Reference link 3">3</a></span> OUD and overdose deaths continue to be a major public health concern in the United States, but they are preventable.</p> <p>People can help reduce the risk of counterfeit pill overdose by:</p> <ul class="nested-list"> <li class="level-1">Only taking pills prescribed to them<ul> </ul> </li> <li class="level-1">Being aware that pills bought illegally might contain highly potent <a href="/stop-overdose/caring/fentanyl-facts.html">drugs</a><ul> </ul> </li> <li class="level-1">Using <a href="/stop-overdose/safety/index.html" class="">fentanyl test strips (FTS)</a>, small strips of paper that can detect the presence of fentanyl in all different kinds of drugs (cocaine, methamphetamine, heroin, etc.) and drug forms (pills, powder, and injectables)<ul> </ul> </li> </ul> <h3>Get the facts</h3> <ul class="nested-list"> <li class="level-1"><strong></strong><strong>Overdoses are the leading injury-related cause of death</strong> in the United States and appear to have accelerated during the COVID-19 pandemic.<span class="cdc-references-cite"><a class="cdc-references-cite__link" href="#cdcreference_4" aria-label="Reference link 4">4</a></span><ul> </ul> </li> <li class="level-1">In 2022, <strong>107,941</strong> people died from drug overdoses, which equates to <strong>296 overdoses each day</strong>.<span class="cdc-references-cite"><a class="cdc-references-cite__link" href="#cdcreference_5" aria-label="Reference link 5">5</a></span><ul> </ul> </li> <li class="level-1">Among the 2022 overdose deaths, nearly <strong>76% involved an opioid</strong>.<span class="cdc-references-cite"><a class="cdc-references-cite__link" href="#cdcreference_5" aria-label="Reference link 5">5</a></span><ul> </ul> </li> <li class="level-1">Research shows that people who have had at least one overdose are more likely to have another.<span class="cdc-references-cite"><a class="cdc-references-cite__link" href="#cdcreference_6" aria-label="Reference link 6">6</a></span><ul> </ul> </li> <li class="level-1">In 2022, an <strong>estimated 54.6 million Americans </strong>needed substance use disorder treatment, but <strong>only 13.1 million people</strong> with a substance use disorder in the past year received treatment.<span class="cdc-references-cite"><a class="cdc-references-cite__link" href="#cdcreference_7" aria-label="Reference link 7">7</a></span><ul> </ul> </li> </ul> <div class="dfe-block dfe-callout dfe-callout--standard"><div class="dfe-callout__icon" role="presentation"></div> <h3>International Overdose Awareness Day&lrm;</h3> <div class="dfe-callout__body"><div class="callout-desc">On August 31 of each year, International Overdose Awareness Day (IOAD) is recognized globally as a day to remember and grieve those that we've lost, take action to encourage support and recovery, and help end overdose by spreading awareness about drug overdose prevention. Join us as an IOAD partner by using your voice and platforms to spread messages about ending overdose.</div> </div></div> <figure class="dfe-image dfe-image__small"><div class="image-container calculated-ratio-16-9 aspect-ratio-16-9"><img src="/overdose-prevention/media/images/awareness/ioad-2023/23_IOAD_General_end1_1200x675.png" alt='"End overdose. August 31. International Overdose Awareness Day"'></div> <div class="dfe-image-caption-container"><figcaption class="dfe-image-caption" id="caption-1477">International Overdose Awareness Day is a day to remember those lost to overdose, acknowledge the grief of loved ones left behind, and work to end overdose injury and death.</figcaption><div class="see-more-container"><a href="javascript:void(0)" data-toggle-content="caption-1477" class="see-more">Show More</a></div></div></figure> </div> <div class="dfe-section" data-section="cdc_prevention_pre"> <a class="onThisPageAnchor" id="cdc_prevention_pre-promising-prevention-strategies" name="Promising%20prevention%20strategies" title="Promising prevention strategies"><!-- --></a><h2>Promising prevention strategies</h2> <p>Ways to prevent opioid overdose are to improve opioid prescribing, reduce exposure to opioids, prevent illegal opioid use and prescription opioid misuse, and treat opioid use disorder. There are strategies that can help prevent overdose and support the health and well-being of communities.</p> <ul class="nested-list"> <li class="level-1"><strong>Promote and support the use of the</strong> <a href="/overdose-prevention/hcp/clinical-guidance/index.html" class="">CDC Clinical Practice Guideline for Prescribing Opioids for Pain</a>.<ul> </ul> </li> <li class="level-1"><b>Utilize</b> <a href="/overdose-prevention/php/interventions/prescription-drug-monitoring-programs.html" class="">prescription drug monitoring programs</a>, which are state-run databases that track prescriptions for controlled substances and can help improve opioid prescribing, inform clinical practice, and protect those at risk.<ul> </ul> </li> <li class="level-1"><strong></strong><a href="https://www.cdc.gov/overdose-prevention/about/prescription-opioids.html"><strong>Learn </strong>about the risks of prescription opioids</a> and about the help and resources that are available for someone who may be experiencing opioid use disorder. See CDC's <a href="/rx-awareness/index.html" class="ce-selection"><em>Rx Awareness</em></a> Campaign for shareable resources and information on improving awareness.<ul> </ul> </li> <li class="level-1"><strong>Learn</strong> more about the dangers of <a href="https://www.cdc.gov/stop-overdose/caring/fentanyl-facts.html">illegally made fentanyl</a> and ways to protect yourself and others, like using <a href="https://www.cdc.gov/stop-overdose/safety/index.html">fentanyl test strips</a>.<ul> </ul> </li> <li class="level-1"><strong>Treat opioid use disorder </strong>by increasing access to substance use disorder treatment services, including Medications for Opioid Use Disorder (MOUD). <a href="/rx-awareness/treatment/index.html" class="">Recovery is possible</a>.<ul> </ul> </li> <li class="level-1"><strong>Reverse overdose </strong>by expanding access to <a href="/overdose-prevention/reversing-overdose/index.html" class="">naloxone</a>, a drug used to reverse an opioid overdose, for community members (family members and neighbors) and service providers (i.e., first responders).<ul> </ul> </li> <li class="level-1"><strong>Help</strong> communities put effective practices to work by using <a href="/overdose-prevention/media/pdfs/2018-evidence-based-strategies.pdf" class="" target="_blank">evidence-based strategies [PDF]<span aria-label=" pdf icon" role="img" class="sr-only"></span><span class="cdc-link-icon cdc-link-icon--pdf" aria-hidden="true"></span></a><ul> </ul> </li> </ul> <div class="dfe-block dfe-callout dfe-callout--standard"><div class="dfe-callout__icon" role="presentation"></div> <h3>How to recognize an overdose&lrm;</h3> <div class="dfe-callout__body"><div class="callout-desc"><p>Recognizing an opioid overdose can be difficult. If you aren't sure, it is best to treat the situation like an overdose&mdash;you could save a life. Administer naloxone or another opioid overdose reversal medication (if available) and then call 911. Try to keep the person awake and breathing and lay the person on their side to prevent choking. Do not leave the person alone. </p><p><br></p><p><br></p><p>Signs of an overdose may include:<br>- Unconsciousness or inability to awaken<br>- Slow or shallow breathing or difficulty breathing such as choking sounds or gurgling/snoring noise from a person who cannot be awakened<br>- Discolored skin (especially in nails or lips)<br>- Small, constricted "pinpoint pupils" that don't react to light<br></p></div> </div></div> <h3>Find treatment for substance use disorder, including opioid use disorder</h3> <p>If you or someone close to you needs help for a substance use disorder, talk to your doctor or call SAMHSA's National Helpline at 1-800-662-HELP or go to <a href="http://findtreatment.samhsa.gov/" class="tp-link-policy" data-domain-ext="gov">SAMHSA's Behavioral Health Treatment Services Locator<span class="visually-hidden sr-only" aria-label=" external icon" role="img"></span><span class="cdc-icon-external cdc-link-icon" aria-hidden="true" alt="external icon"></span></a></p> <p><strong>Additional resources:</strong></p> <ul class="nested-list"> <li class="level-1">Find <a href="http://bphc.hrsa.gov/index.html" class="tp-link-policy" data-domain-ext="gov">Local Health Centers<span class="visually-hidden sr-only" aria-label=" external icon" role="img"></span><span class="cdc-icon-external cdc-link-icon" aria-hidden="true" alt="external icon"></span></a><ul> </ul> </li> <li class="level-1"><a href="http://www.samhsa.gov/medication-assisted-treatment/physician-program-data/treatment-physician-locator" class="tp-link-policy" data-domain-ext="gov">Buprenorphine Treatment Practitioner Locator<span class="visually-hidden sr-only" aria-label=" external icon" role="img"></span><span class="cdc-icon-external cdc-link-icon" aria-hidden="true" alt="external icon"></span></a><ul> </ul> </li> <li class="level-1"><a href="http://dpt2.samhsa.gov/treatment/directory.aspx" class="tp-link-policy" data-domain-ext="gov">Opioid Treatment Program Directory<span class="visually-hidden sr-only" aria-label=" external icon" role="img"></span><span class="cdc-icon-external cdc-link-icon" aria-hidden="true" alt="external icon"></span></a><ul> </ul> </li> </ul> </div> <div class="dfe-section" data-section="cdc_prevention_res"> <a class="onThisPageAnchor" id="cdc_prevention_res-resources" name="Resources" title="Resources"><!-- --></a><h2>Resources</h2> <ul class="nested-list"> <li class="level-1"><a href="/overdose-prevention/index.html">Overdose Prevention</a><ul> </ul> </li> <li class="level-1"><a href="/overdose-prevention/php/od2a/index.html" class="">Overdose Data to Action</a><ul> </ul> </li> <li class="level-1"><a href="/overdose-prevention/php/drug-free-communities/index.html" class="">Drug Free Communities</a><ul> </ul> </li> <li class="level-1"><a href="/rx-awareness/index.html" class="">Rx Awareness</a><ul> </ul> </li> <li class="level-1"><a href="https://www.hhs.gov/opioids/prevention/prevention-programs-tools/index.html" class="tp-link-policy" data-domain-ext="gov">HHS Opioid Prevention Programs<span class="visually-hidden sr-only" aria-label=" external icon" role="img"></span><span class="cdc-icon-external cdc-link-icon" aria-hidden="true" alt="external icon"></span></a><ul> </ul> </li> <li class="level-1"><a href="https://www.hhs.gov/opioids/" class="tp-link-policy" data-domain-ext="gov">HHS Opioids Portal<span class="visually-hidden sr-only" aria-label=" external icon" role="img"></span><span class="cdc-icon-external cdc-link-icon" aria-hidden="true" alt="external icon"></span></a><ul> </ul> </li> </ul> </div> </div> <div class="cdc-dfe-body__right page-right-rail"> <aside class="page-right-rail__static noindex" role="complementary"> <div class="on-this-page " data-sid=""> <h2 class="on-this-page__heading"> On This Page </h2> <div class="card-body"> <ul> <li><a href="#cdc_prevention_overview-opioid-use-disorder-and-overdoses-are-preventable">Opioid use disorder and overdoses are preventable</a></li> <li><a href="#cdc_prevention_pre-promising-prevention-strategies">Promising prevention strategies</a></li> <li><a href="#cdc_prevention_res-resources">Resources</a></li> </ul> </div> </div> </aside> <aside class="page-right-rail__dynamic noindex" role="complementary"> <div data-related-nav></div> </aside> </div> </div> <div data-journey-next></div> <section class="container page-mobile-bar"> <time class="page-mobile-bar__item page-mobile-bar__item--date" datetime="2024-05-08 00:00:00"> May 8, 2024 </time> </section> <div class="page-content-sources noindex"> <div class="page-content-sources__header"> <a data-action="summary" class="collapsed" href="#content-sources" role="button" data-bs-toggle="collapse" aria-expanded="false" aria-controls="content-sources" data-cs-toggle="">Sources</a> <a data-action="print" href="#print" class="d-none d-md-block" aria-label="print this page" onclick="window.print()">Print</a> <a data-action="share" href="#share" data-bs-toggle="dropdown" 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accordion-collapse collapse"> <div class="callout callout-content-source" role="status"> <div class="callout-heading">Content Source:</div> <a class="cdc-block-link" href="/injury/">National Center for Injury Prevention and Control</a> </div> <div class="page-content-sources__section page-content-sources__section--references"><label for="page_references">References</label><ol id="page_references"><li id="cdcreference_1">Elizabeth M. Stone, Alene Kennedy-Hendricks, Colleen L. Barry, Marcus A. Bachhuber, Emma E. McGinty, The role of stigma in U.S. primary care physicians’ treatment of opioid use disorder, Drug and Alcohol Dependence, Volume 221, 2021, 108627, ISSN 0376-8716, <a href="https://doi.org/10.1016/j.drugalcdep.2021.108627">https://doi.org/10.1016/j.drugalcdep.2021.108627</a>.</li> <li id="cdcreference_2">Hadland, S. E., Park, T. W., &amp; Bagley, S. M. (2018). Stigma associated with medication treatment for young adults with opioid use disorder: a case series. Addiction science &amp; clinical practice, 13(1), 15. <a href="https://doi.org/10.1186/s13722-018-0116-2">https://doi.org/10.1186/s13722-018-0116-2</a></li> <li id="cdcreference_3">Casillas SM, Pickens CM, Tanz LJ, et alEstimating the ratio of fatal to non-fatal overdoses involving all drugs, all opioids, synthetic opioids, heroin or stimulants, USA, 2010–2020Injury Prevention 2024;30:114-124.</li> <li id="cdcreference_4">National Center for Injury Prevention and Control. WISQARS—Web-based Injury Statistics Query and Reporting System. 2023. Available from: <a href="https://www.cdc.gov/injury/wisqars/index.html">https://www.cdc.gov/injury/wisqars/index.html</a></li> <li id="cdcreference_5">Spencer MR, Garnett MF, Miniño AM. Drug overdose deaths in the United States, 2002–2022. NCHS Data Brief, no 491. Hyattsville, MD: National Center for Health Statistics. 2024. DOI: <a href="https://dx.doi.org/10.15620/cdc:135849">https://dx.doi.org/10.15620/cdc:135849</a></li> <li id="cdcreference_6">Olfson, M., Wall, M., Wang, S., Crystal, S., &amp; Blanco, C. (2018). Risks of fatal opioid overdose during the first year following nonfatal overdose. Drug and alcohol dependence, 190, 112–119. <a href="https://doi.org/10.1016/j.drugalcdep.2018.06.004" target="_blank">https://doi.org/10.1016/j.drugalcdep.2018.06.004</a></li> <li id="cdcreference_7">Substance Abuse and Mental Health Services Administration. (2023). Key substance use and mental health indicators in the United States: Results from the 2022 National Survey on Drug Use and Health (HHS Publication No. PEP23-07-01-006, NSDUH Series H-58). Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration. <a href="https://www.samhsa.gov/data/report/2022-nsduh-annual-national-report">https://www.samhsa.gov/data/report/2022-nsduh-annual-national-report</a></li></ol></div> </div> </div> <section class="container related-pages related-pages__mobile"> <div data-related-nav-mobile></div> </section> </div> </main> <section class="site-footer container noindex"> <div class="row cdc-footer__inner"> <div class="col-lg-3 site-footer__heading"> <h2> <a href="/overdose-prevention/index.html"> <i class="cdc-icon cdc-fa-solid cdc-fa-house"></i> <span class="cdc-footer__super-title" aria-label="Overdose Prevention"> <a href="/overdose-prevention/index.html"> Overdose Prevention </a> <i class="cdc-icon cdc-fa-light cdc-fa-angle-right"></i> </span> </a> </h2> <p>Overdose prevention is a CDC priority that impacts families and communities. Drug overdose is a leading cause of preventable death in the U.S.</p> <a href="/overdose-prevention/site.html" class="btn-outline__half btn btn-outline-white btn-arrow"> View All </a> </div> <div class="col-lg-8 offset-lg-1"> <div class="row site-footer__links"> <div class="col-md-6"> <!-- If Group Site is Enabled, Need at Least 2 Links --> <h3 class="site-footer__links__header"> <a class="cdc-footer__super-link" href="/overdose-prevention/index.html#gen"> <span>For Everyone</span> <span class="cdc-icon cdc-fa-light cdc-fa-angle-right"></span> </a> </h3> <ul> <li> <a data-post-id="828" href="/overdose-prevention/about/index.html"> About </a> </li> <li> <a data-post-id="856" href="/overdose-prevention/prevention/index.html"> Prevention </a> </li> <li> <a data-post-id="859" href="/overdose-prevention/treatment/index.html"> Managing Substance Use Disorders </a> </li> <li> <a data-post-id="538" href="/overdose-prevention/health-equity/index.html"> Health Equity </a> </li> <li> <a 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